glafenine has been researched along with Hepatic Encephalopathy in 2 studies
Glafenine: An anthranilic acid derivative with analgesic properties used for the relief of all types of pain.
glafenine : A carboxylic ester that is 2,3-dihydroxypropyl anthranilate in which the amino group is substituted by a 7-chloroquinolin-4-yl group. A non-steroidal anti-inflammatory drug, glafenine and its hydrochloride salt were used for the relief of all types of pain, but high incidence of anaphylactic reactions resulted in their withdrawal from the market.
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 1 (50.00) | 18.7374 |
1990's | 1 (50.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Brandt, KH | 1 |
Meinders, AE | 1 |
van Leusen, R | 1 |
Bronkhorst, FB | 1 |
Sangster, BS | 1 |
Koek, GH | 1 |
Stricker, BH | 1 |
Veldhuizen, RW | 1 |
de Graaf, P | 1 |
2 other studies available for glafenine and Hepatic Encephalopathy
Article | Year |
---|---|
[Serious to fatal liver damage following taking of glaphenine].
Topics: Aged; Chemical and Drug Induced Liver Injury; Female; Glafenine; Hepatic Encephalopathy; Humans; Mal | 1979 |
[Fatal liver cell necrosis following administration of glafenine].
Topics: Aged; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Glafenine; Hepatic Encephalopat | 1991 |