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glafenine and Hepatic Encephalopathy

glafenine has been researched along with Hepatic Encephalopathy in 2 studies

Glafenine: An anthranilic acid derivative with analgesic properties used for the relief of all types of pain.
glafenine : A carboxylic ester that is 2,3-dihydroxypropyl anthranilate in which the amino group is substituted by a 7-chloroquinolin-4-yl group. A non-steroidal anti-inflammatory drug, glafenine and its hydrochloride salt were used for the relief of all types of pain, but high incidence of anaphylactic reactions resulted in their withdrawal from the market.

Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brandt, KH1
Meinders, AE1
van Leusen, R1
Bronkhorst, FB1
Sangster, BS1
Koek, GH1
Stricker, BH1
Veldhuizen, RW1
de Graaf, P1

Other Studies

2 other studies available for glafenine and Hepatic Encephalopathy

ArticleYear
[Serious to fatal liver damage following taking of glaphenine].
    Nederlands tijdschrift voor geneeskunde, 1979, Oct-13, Volume: 123, Issue:41

    Topics: Aged; Chemical and Drug Induced Liver Injury; Female; Glafenine; Hepatic Encephalopathy; Humans; Mal

1979
[Fatal liver cell necrosis following administration of glafenine].
    Nederlands tijdschrift voor geneeskunde, 1991, Jun-15, Volume: 135, Issue:24

    Topics: Aged; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Glafenine; Hepatic Encephalopat

1991