Page last updated: 2024-10-27

glafenine and Cystic Fibrosis

glafenine has been researched along with Cystic Fibrosis in 1 studies

Glafenine: An anthranilic acid derivative with analgesic properties used for the relief of all types of pain.
glafenine : A carboxylic ester that is 2,3-dihydroxypropyl anthranilate in which the amino group is substituted by a 7-chloroquinolin-4-yl group. A non-steroidal anti-inflammatory drug, glafenine and its hydrochloride salt were used for the relief of all types of pain, but high incidence of anaphylactic reactions resulted in their withdrawal from the market.

Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Carlile, GW1
Yang, Q1
Matthes, E1
Liao, J1
Birault, V1
Sneddon, HF1
Poole, DL1
Hall, CJ1
Hanrahan, JW1
Thomas, DY1

Other Studies

1 other study available for glafenine and Cystic Fibrosis

ArticleYear
The NSAID glafenine rescues class 2 CFTR mutants via cyclooxygenase 2 inhibition of the arachidonic acid pathway.
    Scientific reports, 2022, 03-17, Volume: 12, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclooxygenase 2; Cystic Fibrosis; Cystic

2022