glafenine has been researched along with Cystic Fibrosis in 1 studies
Glafenine: An anthranilic acid derivative with analgesic properties used for the relief of all types of pain.
glafenine : A carboxylic ester that is 2,3-dihydroxypropyl anthranilate in which the amino group is substituted by a 7-chloroquinolin-4-yl group. A non-steroidal anti-inflammatory drug, glafenine and its hydrochloride salt were used for the relief of all types of pain, but high incidence of anaphylactic reactions resulted in their withdrawal from the market.
Cystic Fibrosis: An autosomal recessive genetic disease of the EXOCRINE GLANDS. It is caused by mutations in the gene encoding the CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR expressed in several organs including the LUNG, the PANCREAS, the BILIARY SYSTEM, and the SWEAT GLANDS. Cystic fibrosis is characterized by epithelial secretory dysfunction associated with ductal obstruction resulting in AIRWAY OBSTRUCTION; chronic RESPIRATORY INFECTIONS; PANCREATIC INSUFFICIENCY; maldigestion; salt depletion; and HEAT PROSTRATION.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (100.00) | 2.80 |
Authors | Studies |
---|---|
Carlile, GW | 1 |
Yang, Q | 1 |
Matthes, E | 1 |
Liao, J | 1 |
Birault, V | 1 |
Sneddon, HF | 1 |
Poole, DL | 1 |
Hall, CJ | 1 |
Hanrahan, JW | 1 |
Thomas, DY | 1 |
1 other study available for glafenine and Cystic Fibrosis
Article | Year |
---|---|
The NSAID glafenine rescues class 2 CFTR mutants via cyclooxygenase 2 inhibition of the arachidonic acid pathway.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arachidonic Acid; Cyclooxygenase 2; Cystic Fibrosis; Cystic | 2022 |