glafenine has been researched along with Cholestasis, Intrahepatic in 1 studies
Glafenine: An anthranilic acid derivative with analgesic properties used for the relief of all types of pain.
glafenine : A carboxylic ester that is 2,3-dihydroxypropyl anthranilate in which the amino group is substituted by a 7-chloroquinolin-4-yl group. A non-steroidal anti-inflammatory drug, glafenine and its hydrochloride salt were used for the relief of all types of pain, but high incidence of anaphylactic reactions resulted in their withdrawal from the market.
Cholestasis, Intrahepatic: Impairment of bile flow due to injury to the HEPATOCYTES; BILE CANALICULI; or the intrahepatic bile ducts (BILE DUCTS, INTRAHEPATIC).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glafenine was associated with hepatic injury in 38 cases." | 1.27 | Glafenine-associated hepatic injury. Analysis of 38 cases and review of the literature. ( Blok, AP; Bronkhorst, FB; Stricker, BH, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stricker, BH | 1 |
| Blok, AP | 1 |
| Bronkhorst, FB | 1 |
1 other study available for glafenine and Cholestasis, Intrahepatic
| Article | Year |
|---|---|
Glafenine-associated hepatic injury. Analysis of 38 cases and review of the literature.
Topics: Adult; Aged; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Female; Glafenine; H | 1986 |