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glafenine and Allergy, Drug

glafenine has been researched along with Allergy, Drug in 13 studies

Glafenine: An anthranilic acid derivative with analgesic properties used for the relief of all types of pain.
glafenine : A carboxylic ester that is 2,3-dihydroxypropyl anthranilate in which the amino group is substituted by a 7-chloroquinolin-4-yl group. A non-steroidal anti-inflammatory drug, glafenine and its hydrochloride salt were used for the relief of all types of pain, but high incidence of anaphylactic reactions resulted in their withdrawal from the market.

Research Excerpts

ExcerptRelevanceReference
" Thirty-four patients (17 with asthma and 17 with urticaria), whose case history suggested such intolerance, were challenged orally with increasing doses of seven compounds: acetylsalicylic acid, glafenine, sodium benzoate, sulfur dioxide, potassium sorbate, sodium glutamate, and tartrazine."7.67Value of oral provocation tests to aspirin and food additives in the routine investigation of asthma and chronic urticaria. ( Frei, PC; Genton, C; Pécoud, A, 1985)
"The authors report the case of a 38 year old man who experienced at two month' interval, hypersensitivity reactions to the ingestion of 200 mg tablets of glafenine, complicated on the first occasion by a transmural anterior wall myocardial infarction as the first manifestation of coronary artery disease and on the second occasion by Prinzmetal angina due to posterior wall ischaemia."7.67[Transmural myocardial infarction and Prinzmetal's syndrome in an allergic reaction to glafenine. Physiopathological discussion. Apropos of a case]. ( Bellorini, M; Besse, F; Desaint, MM; Ertel, M; Godard, S; Hooreman, H; Lainée, R; Le Tessier, G; Lévy, M; Sablon, P, 1985)
" Thirty-four patients (17 with asthma and 17 with urticaria), whose case history suggested such intolerance, were challenged orally with increasing doses of seven compounds: acetylsalicylic acid, glafenine, sodium benzoate, sulfur dioxide, potassium sorbate, sodium glutamate, and tartrazine."3.67Value of oral provocation tests to aspirin and food additives in the routine investigation of asthma and chronic urticaria. ( Frei, PC; Genton, C; Pécoud, A, 1985)
"The authors report the case of a 38 year old man who experienced at two month' interval, hypersensitivity reactions to the ingestion of 200 mg tablets of glafenine, complicated on the first occasion by a transmural anterior wall myocardial infarction as the first manifestation of coronary artery disease and on the second occasion by Prinzmetal angina due to posterior wall ischaemia."3.67[Transmural myocardial infarction and Prinzmetal's syndrome in an allergic reaction to glafenine. Physiopathological discussion. Apropos of a case]. ( Bellorini, M; Besse, F; Desaint, MM; Ertel, M; Godard, S; Hooreman, H; Lainée, R; Le Tessier, G; Lévy, M; Sablon, P, 1985)
"The authors report 5 cases of shock type anaphylactic reactions after the ingestion of glafenine."3.65[Anaphylactic accidents due to glaphenine. 5 cases]. ( Barral, C; Faivre, M, 1975)
"Anthranilic acid derivatives are a group of nonsteroidal antiinflammatory drugs that include glafenine and fenamates."1.29Hypersensitivity reactions to anthranilic acid derivatives. ( Cuevas, M; Davila, I; de la Hoz, B; Fernandez-Rivas, M; Losada, E; Quirce, S, 1993)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199012 (92.31)18.7374
1990's1 (7.69)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Weber, S1
Genevray, B1
Pasquier, G1
Chapsal, J1
Bonnin, A1
Degeorges, M1
Fernandez-Rivas, M1
de la Hoz, B1
Cuevas, M1
Davila, I1
Quirce, S1
Losada, E1
Barral, C1
Faivre, M1
Michaud, JL1
Doublet, L1
Kleinknecht, D2
Kanfer, A1
Morel-Maroger, L1
Méry, JP1
Saurat, JH1
Galloppin, L1
Ponvert, C1
Paupe, J1
Leguy, P1
Youinou, P1
Garré, M1
Burtin, C1
Homberg, JC1
Sabbah, A1
Drouet, M1
Bonneau, JC1
Heulin, M1
Le Sellin, J1
Genton, C1
Frei, PC1
Pécoud, A1
Lainée, R1
Desaint, MM1
Godard, S1
Le Tessier, G1
Ertel, M1
Hooreman, H1
Sablon, P1
Bellorini, M1
Lévy, M1
Besse, F1
Habibi, B1
Pastorello, E1
Qualizza, RM1
Luraghi, MT1
Ispano, M1
Villa, AM1
Ortolani, C1
Zanussi, C1
Landais, P1
Goldfarb, B1

Reviews

1 review available for glafenine and Allergy, Drug

ArticleYear
Immunologically mediated drug-induced acute renal failure.
    Contributions to nephrology, 1978, Volume: 10

    Topics: Acute Kidney Injury; Antigens; Basement Membrane; Drug Hypersensitivity; Glafenine; Glomerulonephrit

1978

Other Studies

12 other studies available for glafenine and Allergy, Drug

ArticleYear
Severe coronary spasm during drug-induced immediate hypersensitivity reaction.
    Lancet (London, England), 1982, Oct-09, Volume: 2, Issue:8302

    Topics: Adult; Angioedema; Coronary Vasospasm; Drug Hypersensitivity; Glafenine; Humans; Male; Myocardial In

1982
Hypersensitivity reactions to anthranilic acid derivatives.
    Annals of allergy, 1993, Volume: 71, Issue:6

    Topics: Drug Hypersensitivity; Female; Glafenine; Humans; Meclofenamic Acid; Middle Aged; ortho-Aminobenzoat

1993
[Anaphylactic accidents due to glaphenine. 5 cases].
    La Nouvelle presse medicale, 1975, Nov-15, Volume: 4, Issue:39

    Topics: Adult; Anaphylaxis; Chemical Phenomena; Chemistry; Drug Hypersensitivity; Edema; Female; Glafenine;

1975
[Letter: Glaphenine-induced shock. 6 recent cases].
    La Nouvelle presse medicale, 1976, Mar-13, Volume: 5, Issue:11

    Topics: Drug Hypersensitivity; Glafenine; Humans; ortho-Aminobenzoates; Skin Manifestations

1976
Leucocyte migration test and hypersensitivity to glafenin.
    Allergy, 1978, Volume: 33, Issue:3

    Topics: Adult; Aged; Cell Migration Inhibition; Cell Movement; Drug Hypersensitivity; Female; Glafenine; Hum

1978
[Glafenin intolerance without any evidence of immunologic mechanism, a case report (author's transl)].
    La Presse medicale, 1979, Dec-10, Volume: 8, Issue:48

    Topics: Drug Hypersensitivity; Fever; Glafenine; Humans; Male; Middle Aged; ortho-Aminobenzoates; Prostaglan

1979
[Interpretation of reactions to acetylsalicylic acid and glaphenine].
    Allergie et immunologie, 1986, Volume: 18, Issue:3

    Topics: Adult; Anaphylaxis; Angioedema; Aspirin; Drug Hypersensitivity; Glafenine; Histamine Release; Humans

1986
Value of oral provocation tests to aspirin and food additives in the routine investigation of asthma and chronic urticaria.
    The Journal of allergy and clinical immunology, 1985, Volume: 76, Issue:1

    Topics: Adult; Angioedema; Aspirin; Asthma; Drug Hypersensitivity; Food Additives; Glafenine; Humans; Middle

1985
[Transmural myocardial infarction and Prinzmetal's syndrome in an allergic reaction to glafenine. Physiopathological discussion. Apropos of a case].
    Archives des maladies du coeur et des vaisseaux, 1985, Volume: 78, Issue:6

    Topics: Adult; Angina Pectoris, Variant; Drug Hypersensitivity; Glafenine; Humans; Male; Myocardial Infarcti

1985
Drug induced red blood cell autoantibodies co-developed with drug specific antibodies causing haemolytic anaemias.
    British journal of haematology, 1985, Volume: 61, Issue:1

    Topics: Aged; Anemia, Hemolytic, Autoimmune; Antibodies; Antibody Specificity; Autoantibodies; Drug Hypersen

1985
[Occurrence of drug reactions].
    Bollettino dell'Istituto sieroterapico milanese, 1986, Volume: 65, Issue:1

    Topics: Acetaminophen; Adult; Anaphylaxis; Angioedema; Aspirin; Asthma; Drug Hypersensitivity; Emergencies;

1986
[Acute renal failure associated with drugs or iodinated contrast media. Results of a cooperative multicentric study by the Nephrology Society].
    Nephrologie, 1986, Volume: 7, Issue:2

    Topics: Acute Kidney Injury; Adult; Aged; Anemia, Hemolytic; Anti-Bacterial Agents; Contrast Media; Drug Hyp

1986