Page last updated: 2024-09-03

ginsenoside rh2 and Liver Neoplasms

ginsenoside rh2 has been researched along with Liver Neoplasms in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (9.52)18.2507
2000's3 (14.29)29.6817
2010's8 (38.10)24.3611
2020's8 (38.10)2.80

Authors

AuthorsStudies
Chen, C; Jin, YH; Li, Y; Wang, YS; Zhang, SY1
Chen, F; Deng, ZY; Hu, QR; Li, J; Luo, T; Wei, WC; Wu, HC; Wu, HJ; Xu, QY; Zheng, LF1
Chen, C; Jin, YH; Li, GA; Li, Y; Liu, WY; Wang, YS; Zhang, ET1
Feng, X; Liu, W; Wang, S; Yang, Q; Yu, B; Yu, X1
Guan, W; Qi, W1
Chen, F; Deng, ZY; Hong, H; Hu, QR; Huang, QX; Li, J; Luo, T; Pan, Y1
Han, W; Huang, W; Ma, Y; Sun, L; Wang, B; Wang, L; Yao, D1
Jing, L; Long, CD; Mei, QH; Qiang, FZ; Qiang, SQ; Qin, GC1
Jin, YH; Li, H; Li, Y; Lin, Y; Song, Z; Wang, YS1
Chen, WW; Hu, ZB; Huang, YF; Liu, DB; Liu, YM; Xiao, HX; Zhuang, YZ1
Guo, Q; Guo, XX; Jin, YH; Lee, SK; Li, Y; Wei, XN1
Chen, D; Feng, Z; Li, D; Li, J; Luo, L; Shi, Q; Xia, J; You, Z; Zhao, L; Zuo, G1
Chen, W; Qiu, Y1
Liu, H; Yang, Z; Zhang, L; Zhao, T1
Chen, DL; Chen, Y; Guo, P; Li, H; Li, J; Shi, Q; Shi, X; Wang, F; Xiong, W; Zuo, G1
Kang, HS; Kim, JS; Kim, SJ; Park, HM1
Tu, ZG; Zeng, XL3
Chung, E; Kim, SI; Lee, KY; Lee, SK; Lee, YH; Park, JA1
Kim, KW; Kim, SI; Lee, SK; Park, JA1

Reviews

1 review(s) available for ginsenoside rh2 and Liver Neoplasms

ArticleYear
Ginsenoside Rh2: A shining and potential natural product in the treatment of human nonmalignant and malignant diseases in the near future.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 118

    Topics: Animals; Carcinoma, Hepatocellular; China; Ginsenosides; Humans; Liver Neoplasms; Panax

2023

Other Studies

20 other study(ies) available for ginsenoside rh2 and Liver Neoplasms

ArticleYear
(20S) Ginsenoside Rh2 Inhibits STAT3/VEGF Signaling by Targeting Annexin A2.
    International journal of molecular sciences, 2021, Aug-27, Volume: 22, Issue:17

    Topics: Annexin A2; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Ginsenosides; Humans; Liver Neoplasms; STAT3 Transcription Factor; Tumor Cells, Cultured; Vascular Endothelial Growth Factor A

2021
The immunomodulatory effects of ginsenoside derivative Rh2-O on splenic lymphocytes in H22 tumor-bearing mice is partially mediated by TLR4.
    International immunopharmacology, 2021, Volume: 101, Issue:Pt B

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Ginsenosides; Liver Neoplasms; Lymphocytes; Mice; Spleen; Toll-Like Receptor 4

2021
(20S) Ginsenoside Rh2 Exerts Its Anti-Tumor Effect by Disrupting the HSP90A-Cdc37 System in Human Liver Cancer Cells.
    International journal of molecular sciences, 2021, Dec-06, Volume: 22, Issue:23

    Topics: Apoptosis; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Cycle; Cell Cycle Proteins; Cell Proliferation; Chaperonins; Gene Expression Regulation, Neoplastic; Ginsenosides; HSP90 Heat-Shock Proteins; Humans; Liver Neoplasms; Tumor Cells, Cultured

2021
20(s)-ginsenoside Rh2 promotes TRAIL-induced apoptosis by upregulating DR5 in human hepatocellular carcinoma cells.
    Medical oncology (Northwood, London, England), 2022, May-15, Volume: 39, Issue:5

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Ginsenosides; Humans; Liver Neoplasms; Mice; Receptors, TNF-Related Apoptosis-Inducing Ligand; TNF-Related Apoptosis-Inducing Ligand; Up-Regulation

2022
Ginsenoside Rh2 and its octyl ester derivative inhibited invasion and metastasis of hepatocellular carcinoma via the c-Jun/COX2/PGE2 pathway.
    Phytomedicine : international journal of phytotherapy and phytopharmacology, 2023, Volume: 121

    Topics: Animals; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclooxygenase 2; Dinoprostone; Esters; Ginsenosides; Liver Neoplasms; Mice

2023
Ginsenosides, potent inhibitors of sialyltransferase.
    Zeitschrift fur Naturforschung. C, Journal of biosciences, 2020, Jan-28, Volume: 75, Issue:1-2

    Topics: Gene Expression Regulation, Neoplastic; Ginsenosides; Hep G2 Cells; Humans; Liver Neoplasms; Molecular Docking Simulation; Sialic Acids; Sialyltransferases

2020
Anticancer Effect of Rh2, a Histone Deacetylase Inhibitor, in HepG2 Cells and HepG2 Cell-Derived Xenograft Tumors Occurs via the Inhibition of HDACs and Activation of the MAPK Signaling Pathway.
    Asian Pacific journal of cancer prevention : APJCP, 2021, Aug-01, Volume: 22, Issue:8

    Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; Ginsenosides; Histone Deacetylase Inhibitors; Histone Deacetylases; Humans; Liver Neoplasms; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Mice, Nude; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2021
The identification of molecular target of (20S) ginsenoside Rh2 for its anti-cancer activity.
    Scientific reports, 2017, 09-29, Volume: 7, Issue:1

    Topics: Annexin A2; Antineoplastic Agents; Apoptosis; Carcinoma, Hepatocellular; Ginsenosides; HEK293 Cells; Hep G2 Cells; Humans; Liver Neoplasms; NF-kappa B p50 Subunit

2017
Microarray analysis of altered long non-coding RNA expression profile in liver cancer cells treated by ginsenoside Rh2.
    Journal of Asian natural products research, 2019, Volume: 21, Issue:8

    Topics: Carcinoma, Hepatocellular; Gene Ontology; Ginsenosides; Hep G2 Cells; Humans; Liver Neoplasms; Microarray Analysis; Real-Time Polymerase Chain Reaction; RNA, Long Noncoding; Signal Transduction

2019
Ginsenoside Rh2 induces human hepatoma cell apoptosisvia bax/bak triggered cytochrome C release and caspase-9/caspase-8 activation.
    International journal of molecular sciences, 2012, Nov-22, Volume: 13, Issue:12

    Topics: Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Carcinoma, Hepatocellular; Caspase 8; Caspase 9; Cell Line, Tumor; Cytochromes c; Enzyme Activation; Ginsenosides; Humans; Liver Neoplasms

2012
Effect of ginsenoside Rh2 on the migratory ability of HepG2 liver carcinoma cells: recruiting histone deacetylase and inhibiting activator protein 1 transcription factors.
    Molecular medicine reports, 2014, Volume: 10, Issue:4

    Topics: Cell Movement; Down-Regulation; Ginsenosides; Hep G2 Cells; Histone Deacetylases; Humans; Liver Neoplasms; Matrix Metalloproteinase 3; Repressor Proteins; RNA, Messenger; Tetradecanoylphorbol Acetate; Transcription Factor AP-1

2014
Ginsenoside Rh2 Targets EGFR by Up-Regulation of miR-491 to Enhance Anti-tumor Activity in Hepatitis B Virus-Related Hepatocellular Carcinoma.
    Cell biochemistry and biophysics, 2015, Volume: 72, Issue:2

    Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; ErbB Receptors; Ginsenosides; Hep G2 Cells; Hepatitis B virus; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred NOD; Mice, SCID; MicroRNAs; Signal Transduction; Up-Regulation

2015
Ginsenoside Rh2 inhibits hepatocellular carcinoma through β-catenin and autophagy.
    Scientific reports, 2016, Jan-19, Volume: 6

    Topics: Animals; Antineoplastic Agents, Phytogenic; Autophagy; beta Catenin; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gene Expression; Ginsenosides; Humans; Liver Neoplasms; Mice; Neoplastic Stem Cells; Xenograft Model Antitumor Assays

2016
Anticancer effect of 20(S)-ginsenoside Rh2 on HepG2 liver carcinoma cells: Activating GSK-3β and degrading β-catenin.
    Oncology reports, 2016, Volume: 36, Issue:4

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Proliferation; Chromatin Immunoprecipitation; Cyclin D1; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Ginsenosides; Glycogen Synthase Kinase 3 beta; Hep G2 Cells; Humans; Immunohistochemistry; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Polymerase Chain Reaction; Xenograft Model Antitumor Assays

2016
Reactive oxygen species mediated ginsenoside Rg3- and Rh2-induced apoptosis in hepatoma cells through mitochondrial signaling pathways.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2012, Volume: 50, Issue:8

    Topics: Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Ginsenosides; Humans; Liver Neoplasms; Mitochondria, Liver; Reactive Oxygen Species; Signal Transduction

2012
[Induction of differentiation by ginsenoside Rh2 in hepatocarcinoma cell SMMC-7721].
    Ai zheng = Aizheng = Chinese journal of cancer, 2004, Volume: 23, Issue:8

    Topics: Albumins; Alkaline Phosphatase; alpha-Fetoproteins; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; gamma-Glutamyltransferase; Ginsenosides; Humans; Liver Neoplasms; Panax; Time Factors

2004
[Effects of ginsenoside Rh2 on signal transduction in hepatocarcinoma SMMC-7721 cells].
    Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology, 2004, Volume: 12, Issue:9

    Topics: Carcinoma, Hepatocellular; Cell Transformation, Neoplastic; Ginsenosides; Humans; Liver Neoplasms; Signal Transduction

2004
[Effect of telomerase on ginsenoside Rh2-induced differentiation of hepatocarcinoma cell line SMMC-7721].
    Ai zheng = Aizheng = Chinese journal of cancer, 2004, Volume: 23, Issue:12

    Topics: Carcinoma, Hepatocellular; Cell Cycle; Cell Cycle Proteins; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p21; DNA-Binding Proteins; Drugs, Chinese Herbal; Ginsenosides; Humans; Liver Neoplasms; Panax; Plants, Medicinal; RNA, Messenger; Telomerase

2004
Ginsenoside-Rh2 blocks the cell cycle of SK-HEP-1 cells at the G1/S boundary by selectively inducing the protein expression of p27kip1.
    Cancer letters, 1996, Dec-20, Volume: 110, Issue:1-2

    Topics: Animals; Cell Cycle Proteins; COS Cells; Cyclin-Dependent Kinase Inhibitor p27; Cyclin-Dependent Kinases; DNA, Neoplasm; Down-Regulation; G1 Phase; Ginsenosides; HeLa Cells; Humans; Liver Neoplasms; Microtubule-Associated Proteins; Rats; Saponins; Tumor Cells, Cultured; Tumor Suppressor Proteins

1996
Caspase 3 specifically cleaves p21WAF1/CIP1 in the earlier stage of apoptosis in SK-HEP-1 human hepatoma cells.
    European journal of biochemistry, 1998, Oct-01, Volume: 257, Issue:1

    Topics: Amino Acid Sequence; Apoptosis; Base Sequence; Carcinoma, Hepatocellular; Caspase 3; Caspases; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinases; Cyclins; DNA Primers; Enzyme Activation; Enzyme Inhibitors; Ginsenosides; Humans; Hydrolysis; Liver Neoplasms; Molecular Sequence Data; Saponins; Sequence Homology, Amino Acid; Staurosporine; Tumor Cells, Cultured

1998