ginsenoside-rh1 has been researched along with Carcinoma--Non-Small-Cell-Lung* in 1 studies
1 other study(ies) available for ginsenoside-rh1 and Carcinoma--Non-Small-Cell-Lung
| Article | Year |
|---|---|
Preparation of Polyethylene Glycol-Ginsenoside Rh1 and Rh2 Conjugates and Their Efficacy against Lung Cancer and Inflammation.
Low solubility and tumor-targeted delivery of ginsenosides to avoid off-target cytotoxicity are challenges for clinical trials. In the present study, we report on a methodology for the synthesis of polyethylene glycol (PEG)-ginsenoside conjugates through a hydrolysable ester bond using the hydrophilic polymer polyethylene glycol with the hydrophobic ginsenosides Rh1 and Rh2 to enhance water solubility and passive targeted delivery. The resulting conjugates were characterized by Topics: A549 Cells; Animals; Antineoplastic Agents, Phytogenic; Carcinoma, Non-Small-Cell Lung; Drug Delivery Systems; Ginsenosides; Humans; Inflammation; Lung Neoplasms; Macrophages; Mice; Polyethylene Glycols; RAW 264.7 Cells | 2019 |