ginkgolide b has been researched along with Disease Models, Animal in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (14.89) | 18.7374 |
| 1990's | 13 (27.66) | 18.2507 |
| 2000's | 6 (12.77) | 29.6817 |
| 2010's | 16 (34.04) | 24.3611 |
| 2020's | 5 (10.64) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
| Chang, C; Gao, Y; Li, S; Yang, G; Yu, D; Zhang, J; Zhang, Y; Zhao, Y | 1 |
| Cao, F; Fang, X; Jiang, Y; Wu, T; Xu, J; Zhao, L | 1 |
| Chen, J; Lv, Z; Shan, X; Tu, Q; Wang, J; Yang, Y | 1 |
| Hao, Y; Huang, P; Lin, D; Luo, T; Shen, W; Shi, R; Wei, C; Wu, A | 1 |
| Cai, N; Fan, M; Hong, H; Jin, F; Liu, S; Sun, C; Wu, L; Yang, X; Zhao, Y; Zheng, T; Zhou, X; Zhu, L | 1 |
| Jang, CG; Jeong, JH; Kim, HC; Lee, YJ; Nabeshima, T; Nah, SY; Park, SJ; Shin, EJ; Tran, HQ; Tran, TV | 1 |
| Han, D; Hu, B; Li, J; Luo, Q; Shen, C; Xu, L; Zhang, D; Zhang, R | 1 |
| Guo, C; Lv, F; Si, A; Zhang, J; Zhang, P; Zhang, Z; Zhao, G; Zhao, L | 1 |
| Chen, K; Xia, SH; Xiang, XH; Xu, W | 1 |
| Jiang, CM; Li, D; Quan, WQ; Wan, HY; Wang, X; Wu, JL; Wu, KY | 1 |
| Huang, HM; Huang, JF; Wang, ZJ; Yang, YF; Yao, Y; Zhao, HP | 1 |
| Allan, KC; Bellizzi, MJ; Geathers, JS; Gelbard, HA | 1 |
| Ding, JH; Du, RH; Hu, G; Li, HQ; Lu, M; Shan, H; Shu, XD; Shu, ZM; Sun, XY; Sun, Y; Xiao, M | 1 |
| Cao, XC; Li, BS; Zhang, G; Zheng, JL; Zhuo, WK | 1 |
| Bai, L; Deng, Y; Fang, F; Fang, W; Li, Y; Lv, P; Mao, L; Qi, Y; Shang, E; Yan, F | 1 |
| Li, FJ; Liu, YG; Wang, J; Wang, XD | 1 |
| Fang, W; Geng, X; Li, Y; Lv, P; Sha, L; Yang, Q | 1 |
| Dong, XQ; Hu, YY; Huang, M; Xu, QP; Yu, WH; Zhang, ZY | 1 |
| Gao, J; Li, W; Li, X; Xia, Y; Yang, B; Zhou, H; Zhou, L | 1 |
| Ge, JB; Gu, JH; Li, M; Qin, ZH; Wu, F; Zhang, W | 1 |
| Hua, Y; Karabiyikoglu, M; Keep, R; Xi, G | 1 |
| Basayiannis, AC; Demopoulos, CA; Grypioti, AD; Mykoniatis, MG; Papadopoulou-Daifoti, Z; Theocharis, SE | 1 |
| Sun, M; Wang, LJ | 1 |
| Demopoulos, CA; Grypioti, AD; Kostopanagiotou, G; Mykoniatis, M; Roussos, A | 1 |
| Chin, TK; Hofmann, PA; Leary, PJ; Morrison, RR; Rajasekaran, S; Tuomanen, EI | 1 |
| Chyczewski, L; Dabrowski, A; Gabryelewicz, A | 1 |
| Denizot, Y; Nathan, N | 1 |
| Brunet, F; Dhainaut, JF; Mira, JP | 1 |
| Christopherson, TJ; Hofer, RE; Lanier, WL; Milde, JH; Scheithauer, BW | 1 |
| Alsina, J; Bordalba, JR; Carrera, M; Griño, JM; Martinez-Castelao, A; Moliner, R; Seron, D; Torras, J; Valles, J | 1 |
| Becker, K; Förster, W; Grupe, R; Lueddeckens, G | 1 |
| Endo, S; Hirashima, Y; Karasawa, K; Nojima, S; Otsuji, T; Takaku, A | 1 |
| Figueiredo, JF; Garcia, WE; Gontijo, JA; Homsi, E; Oliveira Dias, EP | 1 |
| Chyczewski, L; Debek, W; Makarewicz, M | 1 |
| Li, S; Meng, Q; Zhang, L | 1 |
| Bozza, MT; Bozza, PT; Caiado, LF; Castro-Faria-Neto, HC; de Assis, EF; Marathe, GK; McIntyre, TM; Prescott, SM; Silva, AR; Zimmerman, GA | 1 |
| Doly, M; Droy-Lefaix, MT; Jung, H; Munz, K; Remé, C; Wei, Q | 1 |
| Baskin, DG; Beck, JC; Braquet, P; Glidden, D; Goodner, CJ; Lernmark, A; Wilson, C; Wilson, D | 1 |
| Bernabeu, F; Braquet, P; Gómez-Garre, D; López-Farré, A; López-Novoa, JM; Perez-Rodrigo, P; Ramón y Cajal, S | 1 |
| Bigaud, M; Parratt, JR; Wainwright, CL | 1 |
| Braquet, P; Bricio, T; Cobo, ME; Egido, J; González, E; Hernando, L; Mampaso, FM; Martínez-Montero, JC; Pirotzky, E | 1 |
| Bienvenu, P; Braquet, M; Ducousso, R; Gerasimo, P; Kergonou, JF; Lavaud, P; Mathieu, J | 1 |
| Braquet, P; De Giaccobi, G; Jancar, S; Mariano, M; Mencia-Huerta, JM; Sirois, P | 1 |
| Wallace, JL | 1 |
| Lagente, V; Steel, G; Vargaftig, B; Wallace, JL; Whittle, BJ | 1 |
| Csatò, M; Czarnetzki, BM | 1 |
1 review(s) available for ginkgolide b and Disease Models, Animal
| Article | Year |
|---|---|
Platelet-activating factor antagonists as therapeutic strategy in sepsis.
Topics: Animals; Clinical Trials as Topic; Disease Models, Animal; Diterpenes; Endotoxins; Ginkgolides; Hemodynamics; Humans; Lactones; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Sepsis; Shock, Septic | 1994 |
46 other study(ies) available for ginkgolide b and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Ginkgolide B inhibits NLRP3 inflammasome activation and promotes microglial M2 polarization in Aβ
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Disease Models, Animal; Ginkgolides; Humans; Inflammasomes; Lactones; Mice; Microglia; Neuroinflammatory Diseases; NLR Family, Pyrin Domain-Containing 3 Protein; Peptide Fragments | 2021 |
Synergistic Effects of Ginkgolide B and Protocatechuic Acid on the Treatment of Parkinson's Disease.
Topics: Animals; Apoptosis; Biomarkers; Cell Survival; Disease Models, Animal; Drug Synergism; Gene Expression; Ginkgolides; Hydroxybenzoates; Lactones; Mice; Mitochondria; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; PC12 Cells; Rats; Signal Transduction | 2020 |
Ginkgolide B treatment regulated intestinal flora to improve high-fat diet induced atherosclerosis in ApoE
Topics: Animals; Atherosclerosis; Bacteroides; Diet, High-Fat; Disease Models, Animal; Fibrinolytic Agents; Gastrointestinal Microbiome; Ginkgolides; Humans; Hypoglycemia; Inflammation; Lactones; Lipid Metabolism; Male; Methylamines; Mice; Mice, Inbred C57BL; Mice, Knockout, ApoE; Oxygenases; Phthalic Anhydrides; Plaque, Atherosclerotic; RNA, Ribosomal, 16S | 2021 |
Ginkgolide B‑mediated therapeutic effects on perioperative neurocognitive dysfunction are associated with the inhibition of iNOS‑mediated production of NO.
Topics: Animals; Apoptosis; Cognitive Dysfunction; Disease Models, Animal; Ginkgolides; Hippocampus; Lactones; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Neurocognitive Disorders; Nitric Oxide; Nitric Oxide Synthase Type II; Superoxide Dismutase; Therapeutics; Up-Regulation | 2021 |
Neuroprotective effects of Ginkgo biloba extract and Ginkgolide B against oxygen-glucose deprivation/reoxygenation and glucose injury in a new in vitro multicellular network model.
Topics: Animals; Apoptosis; Brain Ischemia; Cell Survival; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Ginkgo biloba; Ginkgolides; Glucose; Lactones; Neurons; Neuroprotective Agents; Oxygen; Plant Extracts; Rats; Stroke | 2018 |
Blockade of platelet-activating factor receptor attenuates abnormal behaviors induced by phencyclidine in mice through down-regulation of NF-κB.
Topics: Animals; Antipsychotic Agents; Disease Models, Animal; Down-Regulation; Ginkgolides; Hippocampus; Lactones; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Phencyclidine; Platelet Membrane Glycoproteins; Prefrontal Cortex; Psychoses, Substance-Induced; Pyrrolidines; Receptors, G-Protein-Coupled; RNA, Messenger; Thiocarbamates | 2018 |
Cardioprotection of Ginkgolide B on Myocardial Ischemia/Reperfusion-Induced Inflammatory Injury via Regulation of A20-NF-κB Pathway.
Topics: Animals; Cardiotonic Agents; Disease Models, Animal; DNA-Binding Proteins; Ginkgolides; Lactones; Male; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Signal Transduction; Transcription Factor RelA; Tumor Necrosis Factor alpha-Induced Protein 3 | 2018 |
Ginkgolide B ameliorates myocardial ischemia reperfusion injury in rats via inhibiting endoplasmic reticulum stress.
Topics: Animals; Disease Models, Animal; Endoplasmic Reticulum Stress; Fibrinolytic Agents; Ginkgolides; Lactones; Male; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley | 2019 |
Roles of BN52021 in platelet-activating factor pathway in inflammatory MS1 cells.
Topics: Adenylyl Cyclases; Animals; Cell Line; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Fibrinolytic Agents; G-Protein-Coupled Receptor Kinases; Ginkgolides; Inflammation; Islets of Langerhans; Lactones; Lipopolysaccharides; Mice; p38 Mitogen-Activated Protein Kinases; Phospholipase C beta; Phospholipases A2; Platelet Activating Factor; Protein-Tyrosine Kinases; Signal Transduction | 2013 |
Neuroprotection against permanent focal cerebral ischemia by ginkgolides A and B is associated with obstruction of the mitochondrial apoptotic pathway via inhibition of c-Jun N-terminal kinase in rats.
Topics: Animals; Apoptosis; Blotting, Western; Brain Ischemia; Disease Models, Animal; Ginkgolides; Immunohistochemistry; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Lactones; Male; Mitochondria; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species | 2014 |
Protective effect of high concentration of BN52021 on retinal contusion in cat eyes.
Topics: Animals; Cats; Contusions; Disease Models, Animal; Electroretinography; Eye Injuries; Female; Fibrinolytic Agents; Ginkgolides; Intraocular Pressure; Lactones; Male; Nerve Fibers; Platelet Activating Factor; Retina; Retinal Diseases; Retinal Ganglion Cells; Tomography, Optical Coherence; Tonometry, Ocular | 2015 |
Platelet-Activating Factor Receptors Mediate Excitatory Postsynaptic Hippocampal Injury in Experimental Autoimmune Encephalomyelitis.
Topics: Animals; Calcium-Binding Proteins; Cell Line, Tumor; Chromosome Pairing; Coculture Techniques; Disease Models, Animal; Disks Large Homolog 4 Protein; Encephalomyelitis, Autoimmune, Experimental; Female; Fibrinolytic Agents; Ginkgolides; Gray Matter; Guanylate Kinases; Hippocampus; Lactones; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microglia; Myelin-Oligodendrocyte Glycoprotein; Peptide Fragments; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Vesicular Glutamate Transport Protein 1 | 2016 |
Ginkgolide B Protects Against Ischemic Stroke Via Modulating Microglia Polarization in Mice.
Topics: Animals; Brain Edema; Cell Hypoxia; Cell Polarity; Cells, Cultured; Cerebral Cortex; Culture Media, Conditioned; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Gene Expression Regulation; Ginkgolides; Glucose; Infarction, Middle Cerebral Artery; Lactones; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Microglia; Motor Activity; Nerve Tissue Proteins | 2016 |
Alleviation of spinal cord injury by Ginkgolide B via the inhibition of STAT1 expression.
Topics: Animals; Apoptosis; Disease Models, Animal; Ginkgolides; Lactones; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Recovery of Function; Spinal Cord Injuries; STAT1 Transcription Factor | 2016 |
Blood brain barrier permeability and therapeutic time window of Ginkgolide B in ischemia-reperfusion injury.
Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Cells, Cultured; Disease Models, Animal; Dithionite; Endothelial Cells; Ginkgolides; Infarction, Middle Cerebral Artery; Lactones; Male; Permeability; Rats; Rats, Wistar; Reperfusion Injury; Time Factors; Tissue Distribution | 2010 |
[Effects of Ginkgolide B on inflammation induced by cerebral ischemia-reperfusion in rats].
Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Disease Models, Animal; E-Selectin; Ginkgo biloba; Ginkgolides; Infarction, Middle Cerebral Artery; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Lactones; Male; Neuroprotective Agents; Plant Leaves; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha | 2010 |
Therapeutic neuroprotective effects of ginkgolide B on cortex and basal ganglia in a rat model of transient focal ischemia.
Topics: Animals; Basal Ganglia; Blood-Brain Barrier; Cerebral Cortex; Data Interpretation, Statistical; Disease Models, Animal; Ginkgolides; Ischemic Attack, Transient; Lactones; Male; Neuroprotective Agents; Rats; Rats, Sprague-Dawley | 2011 |
Ginkgolide B reduces neuronal cell apoptosis in the hemorrhagic rat brain: possible involvement of Toll-like receptor 4/nuclear factor-kappa B pathway.
Topics: Animals; Apoptosis; Brain; Cerebral Hemorrhage; Disease Models, Animal; Dose-Response Relationship, Drug; Ginkgo biloba; Ginkgolides; Inflammation Mediators; Injections, Intraperitoneal; Interleukin-1beta; Interleukin-6; Lactones; Male; Neurons; Neuroprotective Agents; NF-kappa B; Plants, Medicinal; Rats; Rats, Wistar; Signal Transduction; Time Factors; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2011 |
Ginkgolide B inhibits renal cyst development in in vitro and in vivo cyst models.
Topics: Animals; Apoptosis; Cell Line; Cell Proliferation; Cell Survival; Colforsin; Cyclic AMP; Cystic Fibrosis Transmembrane Conductance Regulator; Disease Models, Animal; Dogs; Female; Ginkgolides; In Vitro Techniques; Kidney; Lactones; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mice, Transgenic; Plant Extracts; Polycystic Kidney, Autosomal Dominant; Pregnancy; Protein Kinase C | 2012 |
Inhibition of NF-κB activation is associated with anti-inflammatory and anti-apoptotic effects of Ginkgolide B in a mouse model of cerebral ischemia/reperfusion injury.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Brain; Brain Ischemia; Disease Models, Animal; Gene Expression Regulation; Ginkgolides; Infarction, Middle Cerebral Artery; Inflammation; Lactones; Male; Mice; Mice, Inbred ICR; Microglia; Neuroprotective Agents; NF-kappa B; Reperfusion Injury; Signal Transduction | 2012 |
Acute subdural hematoma: new model delineation and effects of coagulation inhibitors.
Topics: Animals; Anticoagulants; Arginine; Behavior, Animal; Disease Models, Animal; Diterpenes; Extremities; Fibrinolytic Agents; Ginkgolides; Hematoma, Subdural, Acute; Lactones; Male; Movement; Pipecolic Acids; Psychomotor Performance; Rats; Reproducibility of Results; Sulfonamides; Time Factors | 2005 |
Effect of platelet-activating factor (PAF) receptor antagonist (BN52021) on acetaminophen-induced acute liver injury and regeneration in rats.
Topics: 1-Alkyl-2-acetylglycerophosphocholine Esterase; Acetaminophen; Analysis of Variance; Animals; Apoptosis; Biomarkers; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Ginkgolides; Lactones; Liver Function Tests; Liver Regeneration; Male; Platelet Membrane Glycoproteins; Probability; Random Allocation; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reference Values; Sensitivity and Specificity; Severity of Illness Index | 2006 |
[Effect of platelet activating factor receptor antagonist on the tight junction associated protein between the epithelial cells of intestinal mucosa during endotoxemia in young rats].
Topics: Animals; beta Catenin; Disease Models, Animal; Endotoxemia; Epithelial Cells; Female; Ginkgolides; Intestinal Mucosa; Lactones; Male; Platelet Membrane Glycoproteins; Random Allocation; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; RNA, Messenger; Tight Junctions | 2007 |
Platelet activating factor (PAF) antagonism with ginkgolide B protects the liver against acute injury. importance of controlling the receptor of PAF.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Fibrinolytic Agents; Ginkgolides; Lactones; Liver Diseases; Liver Regeneration; Male; Platelet Membrane Glycoproteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled | 2008 |
A cardioprotective role for platelet-activating factor through NOS-dependent S-nitrosylation.
Topics: Animals; Calcium; Calcium Signaling; Cell Shape; Cyclic GMP; Disease Models, Animal; Enzyme Inhibitors; Female; Ginkgolides; Lactones; Male; Mice; Mice, Inbred C57BL; Muscle Proteins; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Platelet Activating Factor; Rats; Rats, Wistar; Time Factors; Ventricular Function, Left | 2008 |
The effect of platelet activating factor antagonist (BN 52021) on acute experimental pancreatitis with reference to multiorgan oxidative stress.
Topics: Acute Disease; Amylases; Animals; Disease Models, Animal; Diterpenes; Ginkgolides; Lactones; Liver; Lung; Male; Malondialdehyde; Organ Specificity; Oxidative Stress; Pancreas; Pancreatitis; Platelet Activating Factor; Rats; Rats, Wistar; Sulfhydryl Compounds | 1995 |
Platelet-activating factor antagonist and cardiopulmonary bypass.
Topics: Animals; Atrial Function, Left; Blood Pressure; Cardiopulmonary Bypass; Disease Models, Animal; Diterpenes; Fibrinolytic Agents; Ginkgolides; Humans; Lactones; Lung; Platelet Activating Factor; Pulmonary Artery; Swine; Vascular Resistance | 1995 |
The effect of a platelet activating factor antagonist (BN 52021) on neurologic outcome and histopathology in a canine model of complete cerebral ischemia.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Diterpenes; Dogs; Ginkgolides; Hemodynamics; Injections, Intravenous; Lactones; Platelet Activating Factor | 1993 |
Protective effect of the PAF antagonist BN 52021 in an experimental renal warm ischemia model.
Topics: Animals; Creatinine; Disease Models, Animal; Diterpenes; Ginkgolides; Hypertonic Solutions; Infusions, Intravenous; Infusions, Parenteral; Kidney Diseases; Kidney Function Tests; Lactones; Male; Nephrectomy; Plant Extracts; Platelet Activating Factor; Rats; Rats, Wistar; Reperfusion Injury; Sodium | 1993 |
PAF-induced death in NMRI mice--a suitable shock model for testing new PAF receptor antagonists. Correlation with eicosanoid related substances.
Topics: 4,5-Dihydro-1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; Animals; Azepines; Disease Models, Animal; Diterpenes; Eicosanoids; Female; Ginkgolides; Lactones; Masoprocol; Mice; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Shock; Species Specificity; Triazoles | 1993 |
Platelet-activating factor and cerebral vasospasm following subarachnoid hemorrhage.
Topics: Animals; Disease Models, Animal; Diterpenes; Female; Ginkgolides; Immunoglobulin G; Ischemic Attack, Transient; Lactones; Platelet Activating Factor; Pyridinium Compounds; Rabbits; Subarachnoid Hemorrhage | 1993 |
Effects of nifedipine and platelet activating factor antagonist (BN 52021) in glycerol-induced acute renal failure in rats.
Topics: Acute Kidney Injury; Administration, Oral; Analysis of Variance; Animals; Creatinine; Disease Models, Animal; Diterpenes; Fibrinolytic Agents; Ginkgolides; Injections, Intraperitoneal; Kidney Function Tests; Lactones; Male; Nifedipine; Rats; Rats, Wistar; Vasodilator Agents | 1996 |
Platelet-activating factor receptor-antagonist (BN 52021) stabilizes the oxidative-antioxidative balance and attenuates the morphological changes in the gastrointestinal tract in experimental hemorrhagic shock.
Topics: Animals; Digestive System; Disease Models, Animal; Diterpenes; Female; Fibrinolytic Agents; Free Radicals; Ginkgolides; Lactones; Lipid Peroxidation; Malondialdehyde; Oxidation-Reduction; Rats; Rats, Wistar; Shock, Hemorrhagic | 1998 |
Experimental therapy of a platelet-activating factor antagonist (ginkgolide B) on photochemically induced thrombotic cerebral ischaemia in tree shrews.
Topics: Animals; Brain Edema; Brain Ischemia; Disease Models, Animal; Diterpenes; Female; Ginkgolides; Intracranial Thrombosis; Lactones; Male; Neuroprotective Agents; Platelet Activating Factor; Tupaiidae | 1999 |
Monocyte chemoattractant protein-1 and 5-lipoxygenase products recruit leukocytes in response to platelet-activating factor-like lipids in oxidized low-density lipoprotein.
Topics: Animals; Arachidonate 5-Lipoxygenase; Cell Movement; Chemokine CCL2; Chemokines; Disease Models, Animal; Diterpenes; Eosinophils; Ginkgolides; Humans; Inflammation; Lactones; Leukocytes; Lipoproteins, LDL; Mice; Neutrophils; Phospholipids; Platelet Activating Factor; Pleural Effusion; Pleurisy; RNA, Messenger | 2002 |
Light and lithium effects in the rat retina: modification by the PAF antagonist BN 52021.
Topics: Analysis of Variance; Animals; Disease Models, Animal; Diterpenes; Ginkgolides; Image Processing, Computer-Assisted; Lactones; Light; Lithium; Male; Phagosomes; Platelet Activating Factor; Rats; Retina; Retinal Diseases; Rod Cell Outer Segment | 1992 |
Effects of ginkgolide B, a platelet-activating factor inhibitor on insulitis in the spontaneously diabetic BB rat.
Topics: Animals; Diabetes Mellitus, Type 1; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Eosinophils; Female; Ginkgolides; Immunohistochemistry; Islets of Langerhans; Lactones; Male; Pancreatitis; Platelet Activating Factor; Rats; Rats, Inbred BB | 1991 |
Platelet-activating factor mediates glycerol-induced acute renal failure in rats.
Topics: Acute Kidney Injury; Alprazolam; Animals; Disease Models, Animal; Diterpenes; Ginkgolides; Glomerular Filtration Rate; Glycerol; Kidney; Kidney Failure, Chronic; Lactones; Male; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1990 |
The effects of PAF antagonists on arrhythmias and platelets during acute myocardial ischaemia and reperfusion.
Topics: Acute Disease; Animals; Blood Gas Analysis; Cardiac Complexes, Premature; Coronary Disease; Disease Models, Animal; Diterpenes; Dogs; Drug Evaluation, Preclinical; Electrocardiography; Ginkgolides; Hemodynamics; Hydrogen-Ion Concentration; Lactones; Myocardial Reperfusion; Oxygen; Platelet Activating Factor; Platelet Count; Quinolinium Compounds; Random Allocation; Tachycardia; Time Factors; Ventricular Fibrillation | 1989 |
Interstitial mononuclear cell infiltrates in experimental nephrosis: effect of PAF antagonist.
Topics: Acetates; Animals; Antibodies, Monoclonal; Disease Models, Animal; Diterpenes; Doxorubicin; Ginkgolides; Immunoenzyme Techniques; In Vitro Techniques; Kidney; Kidney Glomerulus; Lactones; Male; Nephritis, Interstitial; Nephrotic Syndrome; Platelet Activating Factor; Proteinuria; Puromycin; Rats; Rats, Inbred Strains | 1989 |
Modulation of leucocyte activation in the early phase of the rabbit burn injury.
Topics: Animals; Burns; Calcimycin; Disease Models, Animal; Diterpenes; Free Radicals; Ginkgolides; Lactones; Leukotriene B4; Male; Neutrophils; Platelet Activating Factor; Rabbits; Superoxides | 1988 |
Immune complex induced pancreatitis: effect of BN 52021, a selective antagonist of platelet-activating factor.
Topics: Animals; Capillary Permeability; Disease Models, Animal; Diterpenes; Ginkgolides; Immune Complex Diseases; Lactones; Male; Pancreatitis; Platelet Activating Factor; Rats; Rats, Inbred Strains | 1988 |
Release of platelet-activating factor (PAF) and accelerated healing induced by a PAF antagonist in an animal model of chronic colitis.
Topics: Animals; Colitis; Disease Models, Animal; Diterpenes; Ginkgolides; Lactones; Male; Platelet Activating Factor; Rabbits; Rats; Rats, Inbred Strains; Trinitrobenzenesulfonic Acid | 1988 |
Evidence for platelet-activating factor as a mediator of endotoxin-induced gastrointestinal damage in the rat. Effects of three platelet-activating factor antagonists.
Topics: Animals; Blood Pressure; Disease Models, Animal; Diterpenes; Escherichia coli Infections; Ethanol; Ginkgolides; Glyceryl Ethers; Intestine, Small; Lactones; Lipopolysaccharides; Male; Peptic Ulcer; Peptic Ulcer Hemorrhage; Phospholipid Ethers; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains; Shock, Septic; Stomach; Thiazoles | 1987 |
Effect of BN 52021, a platelet activating factor antagonist, on experimental murine contact dermatitis.
Topics: Animals; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; Diterpenes; Female; Ginkgolides; Lactones; Mice; Mice, Inbred BALB C; Platelet Activating Factor; Skin | 1988 |