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ginkgolide b and Brain Ischemia

ginkgolide b has been researched along with Brain Ischemia in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19903 (11.54)18.7374
1990's5 (19.23)18.2507
2000's5 (19.23)29.6817
2010's8 (30.77)24.3611
2020's5 (19.23)2.80

Authors

AuthorsStudies
Cai, D; Chen, J; Gan, H; Huang, M; Li, S; Liu, X; Luo, Z; Ma, R; Su, J; Wang, Z; Wu, J; Zhong, G1
Chen, J; Han, Y; Hu, J; Jin, Z; Kong, L; Luo, J; Yang, L; Yu, P; Zhang, C; Zhao, C; Zhu, J1
Liu, Y; Lv, X; Pan, K; Wei, X; Yang, B; Yang, M; Zhou, Z1
Chen, J; Hu, Y; Lv, Z; Shan, X; Wang, J; Wu, Q; Yang, Y; Zhou, H1
Fang, W; Fei, Y; Li, Y; Zhao, B; Zhu, J1
Cai, N; Fan, M; Hong, H; Jin, F; Liu, S; Sun, C; Wu, L; Yang, X; Zhao, Y; Zheng, T; Zhou, X; Zhu, L1
Cao, L; Cao, ZY; Luo, YP; Wang, ZZ; Xiao, W; Zhang, H; Zhang, XZ1
Ge, JB; Lu, XJ; Qin, HD; Qin, XF; Xu, F; Xu, HZ1
Jiang, CM; Li, D; Quan, WQ; Wan, HY; Wang, X; Wu, JL; Wu, KY1
Chen, L; Gu, X; Ma, B; Su, J; Wu, X; Zhu, L1
Li, FJ; Liu, YG; Wang, J; Wang, XD1
Feng, W; Li, J; Li, SX; Wang, H; Yang, ZZ1
Ge, JB; Gu, JH; Li, M; Qin, ZH; Wu, F; Zhang, W1
Ahlemeyer, B; Krieglstein, J1
Tao, YX; Xu, Y1
Li, F; Li, SQ; Wang, SR; Zhang, JG1
Li, SQ; Yang, LJ; Zhang, Y1
Domańska-Janik, K; Zabøocka, B1
Christopherson, TJ; Hofer, RE; Lanier, WL; Milde, JH; Scheithauer, BW1
Chen, X1
Li, S; Meng, Q; Zhang, L1
Bastianetto, S; Quirion, R; Zheng, WH1
Krieglstein, J; Mennel, HD; Oberpichler, H; Rossberg, C; Sauer, D1
Bazan, NG; Braquet, P; Marcheselli, VL; Panetta, T; Spinnewyn, B1
Bazan, NG; Birkle, DL; Braquet, P; Kurian, P1
Bazan, N; Blavet, N; Braquet, P; Clostre, F; Spinnewyn, B1

Reviews

2 review(s) available for ginkgolide b and Brain Ischemia

ArticleYear
Pharmacological studies supporting the therapeutic use of Ginkgo biloba extract for Alzheimer's disease.
    Pharmacopsychiatry, 2003, Volume: 36 Suppl 1

    Topics: Alzheimer Disease; Animals; Apoptosis; Brain Ischemia; Cells, Cultured; Cyclopentanes; Diterpenes; Dose-Response Relationship, Drug; Drug Interactions; Flavones; Flavonoids; Furans; Ginkgo biloba; Ginkgolides; Glutamic Acid; Humans; Hypoxia; Lactones; Neurons; Neuroprotective Agents; Plant Extracts; Time Factors

2003
[Progress of pharmacological research on cardiovascular and cerebrovascular effects of Gingko biloba extracts and its enlightenment].
    Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine, 1996, Volume: 16, Issue:7

    Topics: Animals; Blood Circulation; Brain Ischemia; Cerebrovascular Circulation; Diterpenes; Drugs, Chinese Herbal; Free Radical Scavengers; Ginkgolides; Humans; Lactones; Myocardial Reperfusion Injury

1996

Other Studies

24 other study(ies) available for ginkgolide b and Brain Ischemia

ArticleYear
Exposure-Response Analysis and Mechanism of Ginkgolide B's Neuroprotective Effect in Acute Cerebral Ischemia/Reperfusion Stage in Rat.
    Biological & pharmaceutical bulletin, 2022, Volume: 45, Issue:4

    Topics: Animals; Brain Ischemia; Ginkgolides; Lactones; Mammals; Neuroprotective Agents; Rats; Reperfusion; Reperfusion Injury

2022
Ginkgolide B targets and inhibits creatine kinase B to regulate the CCT/TRiC-SK1 axis and exerts pro-angiogenic activity in middle cerebral artery occlusion mice.
    Pharmacological research, 2022, Volume: 180

    Topics: Animals; Brain Ischemia; Creatine Kinase; Endothelial Cells; Ginkgolides; Infarction, Middle Cerebral Artery; Ischemic Stroke; Lactones; Mice; Neovascularization, Pathologic; Neovascularization, Physiologic; Stroke

2022
Brain-targeted ginkgolide B-modified carbonized polymer dots for alleviating cerebral ischemia reperfusion injury.
    Biomaterials science, 2023, May-30, Volume: 11, Issue:11

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Ginkgolides; Rats; Reperfusion Injury

2023
Ginkgolide B attenuates cerebral ischemia-reperfusion injury via inhibition of ferroptosis through disrupting NCOA4-FTH1 interaction.
    Journal of ethnopharmacology, 2024, Jan-10, Volume: 318, Issue:Pt B

    Topics: Animals; Brain Ischemia; Ferroptosis; Infarction, Middle Cerebral Artery; Male; Molecular Docking Simulation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Transcription Factors

2024
XQ-1H promotes cerebral angiogenesis via activating PI3K/Akt/GSK3β/β-catenin/VEGF signal in mice exposed to cerebral ischemic injury.
    Life sciences, 2021, May-01, Volume: 272

    Topics: Animals; beta Catenin; Brain; Brain Ischemia; Cerebrovascular Circulation; China; Ginkgolides; Glycogen Synthase Kinase 3 beta; Infarction, Middle Cerebral Artery; Lactones; Male; Mice; Mice, Inbred C57BL; Microvessels; Neovascularization, Physiologic; Phosphatidylinositol 3-Kinases; Proto-Oncogene Proteins c-akt; Recovery of Function; Signal Transduction; Stroke; Vascular Endothelial Growth Factor A

2021
Neuroprotective effects of Ginkgo biloba extract and Ginkgolide B against oxygen-glucose deprivation/reoxygenation and glucose injury in a new in vitro multicellular network model.
    Frontiers of medicine, 2018, Volume: 12, Issue:3

    Topics: Animals; Apoptosis; Brain Ischemia; Cell Survival; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Ginkgo biloba; Ginkgolides; Glucose; Lactones; Neurons; Neuroprotective Agents; Oxygen; Plant Extracts; Rats; Stroke

2018
[Effect of compatibility of ginkgolide A, ginkgolide B and ginkgolide K].
    Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2018, Volume: 43, Issue:7

    Topics: Animals; Brain Ischemia; Ginkgolides; Lactones; Platelet Activating Factor; Platelet Aggregation; Rats; Reperfusion Injury

2018
Ginkgolide B prevents cathepsin-mediated cell death following cerebral ischemia/reperfusion injury.
    Neuroreport, 2014, Mar-05, Volume: 25, Issue:4

    Topics: Animals; Apoptosis; Brain Ischemia; Cathepsin B; Cathepsin L; Cathepsins; Cell Death; Cerebral Cortex; Down-Regulation; Ginkgolides; Lactones; Male; Mice; Mice, Inbred ICR; Motor Activity; Necrosis; Neuroprotective Agents; Reperfusion Injury; Severity of Illness Index

2014
Neuroprotection against permanent focal cerebral ischemia by ginkgolides A and B is associated with obstruction of the mitochondrial apoptotic pathway via inhibition of c-Jun N-terminal kinase in rats.
    Journal of neuroscience research, 2014, Volume: 92, Issue:2

    Topics: Animals; Apoptosis; Blotting, Western; Brain Ischemia; Disease Models, Animal; Ginkgolides; Immunohistochemistry; In Situ Nick-End Labeling; JNK Mitogen-Activated Protein Kinases; Lactones; Male; Mitochondria; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species

2014
Ginkgolide B Protects Neurons from Ischemic Injury by Inhibiting the Expression of RTP801.
    Cellular and molecular neurobiology, 2015, Volume: 35, Issue:7

    Topics: Adaptor Proteins, Signal Transducing; Animals; Brain Ischemia; Cell Survival; DNA-Binding Proteins; Gene Expression Regulation; Ginkgolides; Lactones; Mice; Neurons; Neuroprotective Agents; Plant Extracts; Transcription Factors

2015
[Effects of Ginkgolide B on inflammation induced by cerebral ischemia-reperfusion in rats].
    Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2010, Volume: 33, Issue:4

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Ischemia; Disease Models, Animal; E-Selectin; Ginkgo biloba; Ginkgolides; Infarction, Middle Cerebral Artery; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Lactones; Male; Neuroprotective Agents; Plant Leaves; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Tumor Necrosis Factor-alpha

2010
Effect of ginkgolide B on striatal extracellular amino acids in middle cerebral artery occluded rats.
    Journal of ethnopharmacology, 2011, Jun-14, Volume: 136, Issue:1

    Topics: Amino Acids; Animals; Aspartic Acid; Brain Ischemia; Corpus Striatum; gamma-Aminobutyric Acid; Ginkgo biloba; Ginkgolides; Glutamic Acid; Glycine; Infarction, Middle Cerebral Artery; Lactones; Male; Phytotherapy; Plant Extracts; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2011
Inhibition of NF-κB activation is associated with anti-inflammatory and anti-apoptotic effects of Ginkgolide B in a mouse model of cerebral ischemia/reperfusion injury.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, Nov-20, Volume: 47, Issue:4

    Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Brain; Brain Ischemia; Disease Models, Animal; Gene Expression Regulation; Ginkgolides; Infarction, Middle Cerebral Artery; Inflammation; Lactones; Male; Mice; Mice, Inbred ICR; Microglia; Neuroprotective Agents; NF-kappa B; Reperfusion Injury; Signal Transduction

2012
Involvement of the NMDA receptor/nitric oxide signal pathway in platelet-activating factor-induced neurotoxicity.
    Neuroreport, 2004, Feb-09, Volume: 15, Issue:2

    Topics: Animals; Brain Ischemia; Cell Death; Cells, Cultured; Diterpenes; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epilepsy; Excitatory Amino Acid Antagonists; Ginkgolides; Lactones; Mice; Nerve Degeneration; Neurons; Neurotoxins; Nitric Oxide; Nitric Oxide Synthase; Platelet Activating Factor; Receptors, N-Methyl-D-Aspartate; Signal Transduction

2004
[The effect of ginkgolide B on astrocyte GFAP expression after the focal cerebral ischemia].
    Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2007, Volume: 38, Issue:2

    Topics: Animals; Astrocytes; Brain Ischemia; Female; Gene Expression Regulation; Ginkgolides; Glial Fibrillary Acidic Protein; Injections; Lactones; Male; Time Factors; Tupaiidae

2007
Improving effect of Ginkgolide B on mitochondrial respiration of ischemic neuron after cerebral thrombosis in tree shrewa.
    Chinese medical journal, 2007, Sep-05, Volume: 120, Issue:17

    Topics: Animals; Brain Ischemia; Female; Ginkgolides; Lactones; Male; Mitochondria; Neuroprotective Agents; Oxygen Consumption; Platelet Activating Factor; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Tupaiidae

2007
PAF antagonist, BN52021, inhibits [3H]D-aspartate release after ischaemia in vitro.
    Neuroreport, 1994, Dec-30, Volume: 6, Issue:1

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Aspartic Acid; Brain Ischemia; Diterpenes; Enzyme Activation; Ginkgolides; Hippocampus; In Vitro Techniques; Isoquinolines; Lactones; Phorbol 12,13-Dibutyrate; Piperazines; Platelet Activating Factor; Potassium; Protein Kinase C; Rats; Rats, Wistar; Tritium

1994
The effect of a platelet activating factor antagonist (BN 52021) on neurologic outcome and histopathology in a canine model of complete cerebral ischemia.
    Anesthesiology, 1993, Volume: 79, Issue:2

    Topics: Animals; Brain Ischemia; Disease Models, Animal; Diterpenes; Dogs; Ginkgolides; Hemodynamics; Injections, Intravenous; Lactones; Platelet Activating Factor

1993
Experimental therapy of a platelet-activating factor antagonist (ginkgolide B) on photochemically induced thrombotic cerebral ischaemia in tree shrews.
    Clinical and experimental pharmacology & physiology, 1999, Volume: 26, Issue:10

    Topics: Animals; Brain Edema; Brain Ischemia; Disease Models, Animal; Diterpenes; Female; Ginkgolides; Intracranial Thrombosis; Lactones; Male; Neuroprotective Agents; Platelet Activating Factor; Tupaiidae

1999
The Ginkgo biloba extract (EGb 761) protects and rescues hippocampal cells against nitric oxide-induced toxicity: involvement of its flavonoid constituents and protein kinase C.
    Journal of neurochemistry, 2000, Volume: 74, Issue:6

    Topics: Alkaloids; Alzheimer Disease; Animals; Antioxidants; Azoles; Benzophenanthridines; Brain Ischemia; Calcium Channel Blockers; Calcium Channels, L-Type; Cells, Cultured; Diterpenes; Enzyme Inhibitors; Estrenes; Flavonoids; Free Radical Scavengers; Ginkgo biloba; Ginkgolides; Hippocampus; Isoindoles; Lactones; Molsidomine; Neurons; Neuroprotective Agents; Nitrendipine; Nitric Oxide; Nitric Oxide Donors; Nitroprusside; Organoselenium Compounds; Oxidative Stress; Phenanthridines; Phosphodiesterase Inhibitors; Plant Extracts; Plants, Medicinal; Protein Kinase C; Pyrrolidinones; Rats; Rats, Sprague-Dawley; Signal Transduction; Vasodilator Agents

2000
PAF antagonist ginkgolide B reduces postischemic neuronal damage in rat brain hippocampus.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1990, Volume: 10, Issue:1

    Topics: Animals; Brain Ischemia; Cell Survival; Diterpenes; Ginkgolides; Hippocampus; Lactones; Male; Necrosis; Neurons; Plant Extracts; Platelet Activating Factor; Rats; Rats, Inbred Strains

1990
Effects of a platelet activating factor antagonist (BN 52021) on free fatty acids, diacylglycerols, polyphosphoinositides and blood flow in the gerbil brain: inhibition of ischemia-reperfusion induced cerebral injury.
    Biochemical and biophysical research communications, 1987, Dec-16, Volume: 149, Issue:2

    Topics: Animals; Blood Pressure; Brain Chemistry; Brain Ischemia; Cerebrovascular Circulation; Diglycerides; Diterpenes; Fatty Acids, Nonesterified; Gerbillinae; Ginkgolides; Lactones; Phosphatidylinositol Phosphates; Phosphatidylinositols; Plant Extracts; Platelet Activating Factor

1987
Platelet-activating factor antagonist BN52021 decreases accumulation of free polyunsaturated fatty acid in mouse brain during ischemia and electroconvulsive shock.
    Journal of neurochemistry, 1988, Volume: 51, Issue:6

    Topics: Animals; Brain; Brain Ischemia; Chromatography; Diglycerides; Dimethyl Sulfoxide; Diterpenes; Electroshock; Fatty Acids, Nonesterified; Ginkgolides; Lactones; Male; Mice; Mice, Inbred BALB C; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositols; Plant Extracts; Platelet Activating Factor

1988
Involvement of platelet-activating factor (PAF) in cerebral post-ischemic phase in Mongolian gerbils.
    Prostaglandins, 1987, Volume: 34, Issue:3

    Topics: Animals; Brain; Brain Ischemia; Carotid Arteries; Diterpenes; Gerbillinae; Ginkgolides; Lactones; Male; Mitochondria; Oxygen Consumption; Plant Extracts; Platelet Activating Factor; Structure-Activity Relationship

1987