gingerol has been researched along with Hyperlipidemias* in 2 studies
2 other study(ies) available for gingerol and Hyperlipidemias
| Article | Year |
|---|---|
Molecular factors involved in the hypolipidemic- and insulin-sensitizing effects of a ginger (Zingiber officinale Roscoe) extract in rats fed a high-fat diet.
Hypolipidemic and hypoglycemic properties of ginger in animal models have been reported. However, information related to the mechanisms and factors involved in the metabolic effects of ginger at a hepatic level are limited. The aim of the present study was to investigate molecular factors involved in the hypoglycemic and hypolipidemic effects of a hydroethanolic ginger extract (GE) in the liver of rats fed a high-fat diet (HFD). The study was conducted in male Wistar rats divided into the following 3 groups: (i) Rats fed a standard diet (3.5% fat), the control group; (ii) rats fed an HFD (33.5% fat); and (iii) rats fed an HFD treated with GE (250 mg·kg Topics: Adiponectin; Animals; Catechols; Diabetes Mellitus, Type 2; Diet, High-Fat; Fatty Alcohols; Glucose Transporter Type 2; Hyperlipidemias; Hypoglycemic Agents; Hypolipidemic Agents; Insulin Resistance; Liver; Male; Overweight; Plant Extracts; Plant Roots; PPAR alpha; PPAR gamma; Rats, Wistar; Up-Regulation; Zingiber officinale | 2017 |
Beneficial effects of Zingiber officinale Roscoe on fructose induced hyperlipidemia and hyperinsulinemia in rats.
Fructose supplementation produced cardinal features of Syndrome-X including significant elevations in seum cholesterol, triglyceride, glucose and insulin and also in body weight. While treatment with methanolic extract of dried rhizomes of Zingiber officinale produced a significant reduction in fructose induced elevation in lipid levels, bodyweight, hyperglycemia and hyperinsulinemia, treatment with ethyl acetate extract of Z officinale did not poduce any significant change in either of the last two parameters. However, it produced a significant reduction in elevated lipid levels and body weight The concentration of 6-gingerol was found to be higher in methanolic extract and less in ethyl acetate extract. The results suggest that the methanolic extract of Z officinale produces better effects as compared to ethyl acetate extract in fructose induced hyperlipidemia associated with insulin resistance. The extent of activity appears to be dependent on the concentration of 6-gingerol present in the extracts. Topics: Animals; Body Weight; Catechols; Diabetes Mellitus, Experimental; Fatty Alcohols; Fructose; Hyperinsulinism; Hyperlipidemias; Metabolic Syndrome; Plant Extracts; Rats; Rhizome; Zingiber officinale | 2005 |