germanium and Hypercholesterolemia

germanium has been researched along with Hypercholesterolemia* in 1 studies

Other Studies

1 other study(ies) available for germanium and Hypercholesterolemia

Article	Year
Effect of germanium-132 on low-density lipoprotein oxidation and atherosclerosis in Kurosawa and Kusanagi hypercholesterolemic rabbits. Bioscience, biotechnology, and biochemistry, 2001, Volume: 65, Issue:8 Germanium-132 (Ge-132) was given at 200 mg/kg of body weight to 8-week-old Kurosawa and Kusanagi hypercholesterolemic (KHC) rabbits. Thirty-six weeks later, the susceptibility of plasma low-density lipoprotein to oxidation and the morphology of atherosclerosis in the aorta and coronary artery were investigated. Treatment with Ge-132 resulted in decreases in the oxidation rate and in the formation rate of thiobarbituric acid-reactive substances following copper-induced oxidation of LDL. Ge-132 is suggested to possess antioxidative properties, but this did not lead to any attenuation of atherosclerotic progression in the KHC rabbits. Topics: Aging; Animals; Anticholesteremic Agents; Aorta, Thoracic; Arteriosclerosis; Female; Germanium; Hypercholesterolemia; Kinetics; Lipoproteins, LDL; Organometallic Compounds; Oxidation-Reduction; Oxidative Stress; Propionates; Rabbits; Thiobarbituric Acid Reactive Substances	2001

Article

Year

Effect of germanium-132 on low-density lipoprotein oxidation and atherosclerosis in Kurosawa and Kusanagi hypercholesterolemic rabbits.

Bioscience, biotechnology, and biochemistry, 2001, Volume: 65, Issue:8

Germanium-132 (Ge-132) was given at 200 mg/kg of body weight to 8-week-old Kurosawa and Kusanagi hypercholesterolemic (KHC) rabbits. Thirty-six weeks later, the susceptibility of plasma low-density lipoprotein to oxidation and the morphology of atherosclerosis in the aorta and coronary artery were investigated. Treatment with Ge-132 resulted in decreases in the oxidation rate and in the formation rate of thiobarbituric acid-reactive substances following copper-induced oxidation of LDL. Ge-132 is suggested to possess antioxidative properties, but this did not lead to any attenuation of atherosclerotic progression in the KHC rabbits.

Topics: Aging; Animals; Anticholesteremic Agents; Aorta, Thoracic; Arteriosclerosis; Female; Germanium; Hypercholesterolemia; Kinetics; Lipoproteins, LDL; Organometallic Compounds; Oxidation-Reduction; Oxidative Stress; Propionates; Rabbits; Thiobarbituric Acid Reactive Substances

2001