geranylgeraniol has been researched along with Multiple Myeloma in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Berghuis, AM; Gómez Palou, M; Huang, XF; Lacbay, CM; Park, J; Sebag, M; Ta, V; Tsantrizos, YS; Vincent, F; Waller, DD | 1 |
| Iguchi, T; Ikeda, Y; Kizaki, M; Miyakawa, Y; Yamamoto, K | 1 |
| Bloem, AC; Kamphuis, MM; Lokhorst, HM; van de Donk, NW; van Kessel, B | 1 |
| Cho, R; Koizumi, M; Nakaseko, C; Nishimura, M; Ohwada, C; Ozawa, S; Saito, Y; Shimizu, N; Takeuchi, M | 1 |
| Croucher, PI; Helfrich, MH; Rogers, MJ; Russell, RG; Shipman, CM | 1 |
5 other study(ies) available for geranylgeraniol and Multiple Myeloma
| Article | Year |
|---|---|
Unraveling the Prenylation-Cancer Paradox in Multiple Myeloma with Novel Geranylgeranyl Pyrophosphate Synthase (GGPPS) Inhibitors.
Topics: Apoptosis; Catalytic Domain; Cell Proliferation; Enzyme Inhibitors; Geranylgeranyl-Diphosphate Geranylgeranyltransferase; Humans; Inhibitory Concentration 50; Models, Molecular; Multiple Myeloma; Protein Prenylation; Pyrimidines; rap1 GTP-Binding Proteins | 2018 |
Nitrogen-containing bisphosphonates induce S-phase cell cycle arrest and apoptosis of myeloma cells by activating MAPK pathway and inhibiting mevalonate pathway.
Topics: Apoptosis; Cell Division; Cell Line, Tumor; Checkpoint Kinase 1; Diphosphonates; Diterpenes; Enzyme Inhibitors; Farnesol; Humans; Imidazoles; Interleukin-6; MAP Kinase Signaling System; Mevalonic Acid; Multiple Myeloma; Phosphorylation; Protein Kinases; S Phase; Signal Transduction; Stromal Cells | 2003 |
Inhibition of protein geranylgeranylation induces apoptosis in myeloma plasma cells by reducing Mcl-1 protein levels.
Topics: Alkyl and Aryl Transferases; Apoptosis; Bone Marrow Cells; Cell Line, Tumor; Diterpenes; Down-Regulation; Drug Antagonism; Enzyme Inhibitors; Humans; Lovastatin; Mitochondria; Mitochondrial Proteins; Multiple Myeloma; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasm Proteins; Protein Prenylation; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 2003 |
Zoledronate has an antitumor effect and induces actin rearrangement in dexamethasone-resistant myeloma cells.
Topics: Actins; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Survival; Dexamethasone; Diphosphonates; Diterpenes; Drug Resistance, Neoplasm; Humans; Imidazoles; Multiple Myeloma; Protein Prenylation; rap1 GTP-Binding Proteins; rhoA GTP-Binding Protein; Zoledronic Acid | 2007 |
The bisphosphonate incadronate (YM175) causes apoptosis of human myeloma cells in vitro by inhibiting the mevalonate pathway.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Division; Diphosphonates; Diterpenes; Enzyme Inhibitors; Farnesol; Humans; Lovastatin; Mevalonic Acid; Multiple Myeloma; Protein Prenylation; Tumor Cells, Cultured | 1998 |