geranylgeraniol has been researched along with Cell Transformation, Neoplastic in 3 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Brenner, DA; Cox, AD; Der, CJ; Garcia, AM; Kowalczyk, JJ; Lewis, MD; Westwick, JK | 1 |
Hamilton, AD; McGuire, TF; Qian, Y; Sebti, SM; Vogt, A | 1 |
Buss, JE; Cox, AD; Der, CJ; Hisaka, MM | 1 |
3 other study(ies) available for geranylgeraniol and Cell Transformation, Neoplastic
Article | Year |
---|---|
The CAAX peptidomimetic compound B581 specifically blocks farnesylated, but not geranylgeranylated or myristylated, oncogenic ras signaling and transformation.
Topics: 3T3 Cells; Animals; Cell Transformation, Neoplastic; Diterpenes; DNA-Binding Proteins; ets-Domain Protein Elk-1; Farnesol; Mice; Myristic Acid; Myristic Acids; Oligopeptides; Oncogene Protein p21(ras); Protein Prenylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-jun; Retroviridae Proteins, Oncogenic; Signal Transduction; Transcription Factors; Transcription, Genetic | 1994 |
Protein geranylgeranylation, not farnesylation, is required for the G1 to S phase transition in mouse fibroblasts.
Topics: Actins; Alkyl and Aryl Transferases; Animals; Benzamides; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Cytoskeleton; Diterpenes; DNA; Enzyme Inhibitors; Farnesol; Fibroblasts; G1 Phase; Genes, ras; GTP-Binding Proteins; Lovastatin; Methionine; Mevalonic Acid; Mice; Protein Prenylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; rap GTP-Binding Proteins; ras Proteins; Resting Phase, Cell Cycle; S Phase; Transferases | 1996 |
Specific isoprenoid modification is required for function of normal, but not oncogenic, Ras protein.
Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cell Division; Cell Membrane; Cell Transformation, Neoplastic; Cysteine; Diterpenes; Farnesol; GTP-Binding Proteins; Mice; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Proto-Oncogene Proteins pp60(c-src); rap GTP-Binding Proteins; Structure-Activity Relationship | 1992 |