gentamicin-sulfate has been researched along with Carcinoma-256--Walker* in 2 studies
2 other study(ies) available for gentamicin-sulfate and Carcinoma-256--Walker
| Article | Year |
|---|---|
Synthesis of (1,4)-naphthoquinono-[3,2-c]-1H-pyrazoles and their (1,4)-naphthohydroquinone derivatives as antifungal, antibacterial, and anticancer agents.
A series of (1,4)-naphthoquinono [3,2-c]-1H-pyrazoles and their (1,4)-naphthohydroquinone derivatives 2-7 were synthesized and evaluated for antifungal, antibacterial, and anticancer activities. The structure-activity relationship of these compounds was studied and the results show that the compound 2b exhibited in vitro antifungal activity against Candida albicans and Cryptococcus neoformans, and also possessed antibacterial profile against Klebsiella pneumoniae and Escherichia coli whereas 1c showed anticancer activity against Walker 256 Carcinosarcoma in rats. Topics: Animals; Anti-Bacterial Agents; Antifungal Agents; Antineoplastic Agents; Candida albicans; Carcinoma 256, Walker; Cryptococcus neoformans; Escherichia coli; Klebsiella pneumoniae; Microbial Sensitivity Tests; Naphthoquinones; Pyrazoles; Rats; Structure-Activity Relationship | 2005 |
Design, synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antifungal and anticancer agents.
A series of 1,4-naphthoquinone derivatives were synthesized and tested for antifungal and antitumor activity against a number of fungal disease causative species and Walker 256 carcinoma cell lines. The results show that the compounds 8a,e and 11b possess pronounced antifungal profile where as 7b and f were found to be active against Walker 256 carcinoma cell lines. Moreover 7c and 11a showed inhibitory effect against reverse transcriptase enzyme from Rauscher Murine Leukemia Virus. Topics: Animals; Antifungal Agents; Antineoplastic Agents; Carcinoma 256, Walker; Drug Design; Drug Evaluation, Preclinical; Microbial Sensitivity Tests; Naphthoquinones | 2004 |