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gentamicin and Wounds, Penetrating

gentamicin has been researched along with Wounds, Penetrating in 28 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Wounds, Penetrating: Wounds caused by objects penetrating the skin.

Research Excerpts

ExcerptRelevanceReference
"The effectiveness of an intraocular injection of combined gentamicin and clindamycin in the prevention of acute posttraumatic bacterial endophthalmitis following penetrating ocular injuries was evaluated in a prospective, double-masked, randomized pilot study."5.09Prophylaxis of acute posttraumatic bacterial endophthalmitis with or without combined intraocular antibiotics: a prospective, double-masked randomized pilot study. ( Peyman, GA; Rafati, N; Soheilian, M, 2001)
"To determine whether a combination of ciprofloxacin hydrochloride and metronidazole hydrochloride would be as effective or more effective than a combination of gentamicin sulfate and metronidazole hydrochloride for preventing infection in patients with penetrating abdominal trauma, to evaluate the factors associated with increased risk of infection, and to determine the serum peak and trough levels of gentamicin with the dosage regimen of 2."5.08A trial of ciprofloxacin and metronidazole vs gentamicin and metronidazole for penetrating abdominal trauma. ( McCreadie, S; Tyburski, JG; Warsow, KM; Wilson, RF, 1998)
"5 g, every 6 hours) were compared with combined gentamicin (80 mg, every 8 hours) and metronidazole (500 mg every 6 hours) therapy in 246 patients hospitalized for penetrating abdominal injuries."5.07Piperacillin monotherapy compared with metronidazole and gentamicin combination in penetrating abdominal trauma. ( Ganesan, N; Lou, MA; Sims, EH; Thadepalli, H; Williams, SW, 1993)
"Aztreonam was administered at a dosage of 2 g every 8 hours and gentamicin at 5 mg/kg for the first 24 hours and then adjusted by serum monitoring to a peak of 6 to 8 micrograms/mL and a trough of less than 2 micrograms/mL; all patients received 900 mg of clindamycin every 8 hours."2.67Superiority of aztreonam/clindamycin compared with gentamicin/clindamycin in patients with penetrating abdominal trauma. ( Boucher, BA; Charland, SL; Croce, MA; Fabian, TC; Hess, MM; Rodman, JH; Wilson, RS; Wilson, SE, 1994)
"Gentamicin was added to each regimen in phase 2."2.67Empiric monotherapy versus combination therapy of nosocomial pneumonia in trauma patients. ( Croce, MA; Fabian, TC; Kudsk, KA; Minard, G; Pritchard, FE; Stewart, RM; Trenthem, L, 1993)
"This study was done to determine if a single drug, mezlocillin (Mezlo), is as safe and as effective as combined clindamycin (Clind) and gentamicin (Gent) in the treatment of penetrating abdominal wounds."2.66Safety and efficacy of mezlocillin: a single-drug therapy for penetrating abdominal trauma. ( Lou, MA; Mandal, AK; Thadepalli, H, 1988)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199017 (60.71)18.7374
1990's8 (28.57)18.2507
2000's2 (7.14)29.6817
2010's1 (3.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hwang, MR1
Kim, JO1
Lee, JH1
Kim, YI1
Kim, JH1
Chang, SW1
Jin, SG1
Kim, JA1
Lyoo, WS1
Han, SS1
Ku, SK1
Yong, CS1
Choi, HG1
Akhondi, H1
Rahimi, AR1
Soheilian, M1
Rafati, N1
Peyman, GA1
Nichols, RL1
Smith, JW1
Klein, DB1
Trunkey, DD1
Cooper, RH1
Adinolfi, MF1
Mills, J1
Iuzhakov, AM1
O'Day, DM1
Smith, RS1
Gregg, CR1
Turnbull, PC1
Head, WS1
Ives, JA1
Ho, PC1
Miron, D1
Raz, R1
Kaufman, B1
Fridus, B1
Fabian, TC3
Hess, MM1
Croce, MA2
Wilson, RS1
Wilson, SE1
Charland, SL1
Rodman, JH1
Boucher, BA1
Stewart, RM1
Pritchard, FE1
Minard, G1
Trenthem, L1
Kudsk, KA1
Sims, EH2
Lou, MA2
Williams, SW1
Ganesan, N1
Thadepalli, H4
Ganesan, K1
Mandal, AK3
Magee, AA1
Ragle, CA1
Howlett, MR1
Tyburski, JG1
Wilson, RF1
Warsow, KM1
McCreadie, S1
Martinez, OV1
Lester, JL1
Arango, A1
Malinin, TI1
O'Donnell, V1
Lou, SM1
LeFrock, JL1
Joseph, BK1
Klainer, AS1
Gainer, RB1
Prince, RA1
Kolodziejczyk, D1
Hirsch, WD1
Moore, FA1
Moore, EE2
Ammons, LA1
McCroskey, BL1
Moore, DC1
Mao, WX1
Le Saux, N1
Harding, GK1
Bivins, BA2
Crots, L1
Sorensen, VJ2
Obeid, FN2
Horst, HM2
Fifer, T1
Crots, LD1
Posner, MC1
Harris, LA1
Allo, MD1
Novikov, FG1
Kreis, DJ1
Augenstein, D1
Martinez, O1
Echenique, M1
Plasencia, G1
Vopal, JJ1
Byers, P1
Gomez, GA1
Boldreghini, SJ1

Reviews

1 review available for gentamicin and Wounds, Penetrating

ArticleYear
Infections following nail puncture wound of the foot: case reports and review of the literature.
    Israel journal of medical sciences, 1993, Volume: 29, Issue:4

    Topics: Abscess; Adolescent; Cellulitis; Child; Debridement; Emergencies; Female; Foot Injuries; Gentamicins

1993

Trials

14 trials available for gentamicin and Wounds, Penetrating

ArticleYear
Prophylaxis of acute posttraumatic bacterial endophthalmitis with or without combined intraocular antibiotics: a prospective, double-masked randomized pilot study.
    International ophthalmology, 2001, Volume: 24, Issue:6

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Child; Child, Preschool; Clindamycin; Double-Blind Method;

2001
Risk of infection after penetrating abdominal trauma.
    The New England journal of medicine, 1984, Oct-25, Volume: 311, Issue:17

    Topics: Abdominal Injuries; Adult; Age Factors; Bacterial Infections; Blood Transfusion; Cefoxitin; Clindamy

1984
Superiority of aztreonam/clindamycin compared with gentamicin/clindamycin in patients with penetrating abdominal trauma.
    American journal of surgery, 1994, Volume: 167, Issue:3

    Topics: Abdominal Injuries; Adult; Aztreonam; Bacterial Infections; Blood Transfusion; Clindamycin; Colon; D

1994
Empiric monotherapy versus combination therapy of nosocomial pneumonia in trauma patients.
    The Journal of trauma, 1993, Volume: 35, Issue:2

    Topics: Adolescent; Adult; Aged; Cefoperazone; Ceftazidime; Cross Infection; Drug Therapy, Combination; Fema

1993
Piperacillin monotherapy compared with metronidazole and gentamicin combination in penetrating abdominal trauma.
    The Journal of trauma, 1993, Volume: 34, Issue:2

    Topics: Abdominal Injuries; Adolescent; Adult; Aged; Drug Administration Schedule; Drug Therapy, Combination

1993
How many antibiotics are necessary to treat abdominal trauma victims?
    The American surgeon, 1997, Volume: 63, Issue:6

    Topics: Abdominal Injuries; Adolescent; Adult; Antibiotic Prophylaxis; Cefoperazone; Ceftriaxone; Cephalospo

1997
A trial of ciprofloxacin and metronidazole vs gentamicin and metronidazole for penetrating abdominal trauma.
    Archives of surgery (Chicago, Ill. : 1960), 1998, Volume: 133, Issue:12

    Topics: Abdominal Injuries; Adult; Anti-Infective Agents; Ciprofloxacin; Double-Blind Method; Drug Therapy,

1998
Presumptive antibiotics for penetrating abdominal wounds.
    Surgery, gynecology & obstetrics, 1989, Volume: 169, Issue:2

    Topics: Abdominal Injuries; Adult; Anti-Bacterial Agents; Clindamycin; Clinical Trials as Topic; Drug Admini

1989
Safety and efficacy of mezlocillin: a single-drug therapy for penetrating abdominal trauma.
    The Journal of trauma, 1988, Volume: 28, Issue:11

    Topics: Abdominal Injuries; Adult; Ascitic Fluid; Bacterial Infections; Clindamycin; Drug Evaluation; Drug T

1988
Preventative antibiotics for penetrating abdominal trauma--single agent or combination therapy?
    Drugs, 1988, Volume: 35 Suppl 2

    Topics: Abdominal Injuries; Bacterial Infections; Cefotaxime; Cefoxitin; Cephalosporins; Clindamycin; Costs

1988
A prospective randomized comparison of a single antibiotic (moxalactam) versus combination therapy (gentamicin and clindamycin) in penetrating abdominal trauma.
    Henry Ford Hospital medical journal, 1988, Volume: 36, Issue:1

    Topics: Abdominal Injuries; Adolescent; Adult; Aged; Bacterial Infections; Clindamycin; Drug Therapy, Combin

1988
Presumptive antibiotics for penetrating abdominal wounds.
    Surgery, gynecology & obstetrics, 1987, Volume: 165, Issue:1

    Topics: Abdominal Injuries; Adult; Clindamycin; Drug Evaluation; Female; Gentamicins; Humans; Male; Mezlocil

1987
A prospective randomized study of moxalactam versus gentamicin and clindamycin in penetrating abdominal trauma.
    Surgery, gynecology & obstetrics, 1986, Volume: 163, Issue:1

    Topics: Abdominal Injuries; Adolescent; Adult; Clindamycin; Drug Evaluation; Drug Therapy, Combination; Fema

1986
Antibiotics in penetrating abdominal trauma. Comparison of ticarcillin plus clavulanic acid with gentamicin plus clindamycin.
    The American journal of medicine, 1985, Nov-29, Volume: 79, Issue:5B

    Topics: Abdominal Injuries; Adolescent; Adult; Bacterial Infections; Clavulanic Acid; Clavulanic Acids; Clin

1985

Other Studies

13 other studies available for gentamicin and Wounds, Penetrating

ArticleYear
Gentamicin-loaded wound dressing with polyvinyl alcohol/dextran hydrogel: gel characterization and in vivo healing evaluation.
    AAPS PharmSciTech, 2010, Volume: 11, Issue:3

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Bandages; Dextrans; Drug Carriers; Gentamic

2010
Haemophilus aphrophilus endocarditis after tongue piercing.
    Emerging infectious diseases, 2002, Volume: 8, Issue:8

    Topics: Adult; Ampicillin; Anti-Bacterial Agents; Cosmetic Techniques; Endocarditis, Bacterial; Gentamicins;

2002
[Prevention of intraocular bacterial wound infection].
    Oftalmologicheskii zhurnal, 1984, Issue:5

    Topics: Bacterial Infections; Drug Therapy, Combination; Eye Injuries; Gentamicins; Humans; Kanamycin; Sulfa

1984
The problem of bacillus species infection with special emphasis on the virulence of Bacillus cereus.
    Ophthalmology, 1981, Volume: 88, Issue:8

    Topics: Abscess; Animals; Bacillus cereus; Bacterial Infections; Child; Clindamycin; Corneal Diseases; Drug

1981
Use of tenoscopy for management of septic tenosynovitis caused by a penetrating porcupine quill in the synovial sheath surrounding the digital flexor tendons of a horse.
    Journal of the American Veterinary Medical Association, 1997, Jun-15, Volume: 210, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Arthroscopes; Arthroscopy; Debridement; Foreign Bodies; Gentamicins;

1997
Antibiotic prophylaxis in penetrating colorectal injuries: the comparative effectiveness of clindamycin and cephalothin in combination with an aminoglycoside.
    The American surgeon, 1979, Volume: 45, Issue:6

    Topics: Adult; Aminoglycosides; Bacterial Infections; Cephalothin; Clindamycin; Colon; Drug Therapy, Combina

1979
Evaluation of carbenicillin and a comparison of clindamycin and gentamicin combined therapy in penetrating abdominal trauma.
    Surgery, gynecology & obstetrics, 1978, Volume: 147, Issue:4

    Topics: Abdominal Injuries; Adolescent; Adult; Aerobiosis; Aminoglycosides; Anaerobiosis; Bacterial Infectio

1978
Infectious arthritis resulting from Enterobacter cloacae and Enterobacter hafniae.
    Clinical pediatrics, 1977, Volume: 16, Issue:9

    Topics: Arthritis, Infectious; Child; Drug Therapy, Combination; Enterobacteriaceae Infections; Gentamicins;

1977
[Epidural "sulmycin implant" coverage for local prevention of infection in surgical management of open craniocerebral injuries].
    Aktuelle Traumatologie, 1992, Volume: 22, Issue:6

    Topics: Adolescent; Adult; Aged; Brain Injuries; Child; Child, Preschool; Craniotomy; Drug Implants; Female;

1992
Intralenticular abscess.
    Australian and New Zealand journal of ophthalmology, 1989, Volume: 17, Issue:3

    Topics: Abscess; Adult; Cataract Extraction; Cephalosporins; Eye Infections, Bacterial; Eye Injuries; Gentam

1989
[A new method in treating open wounds of the fingers with traditional Chinese medicine and Western medicine. An analysis of 2,000 cases].
    Zhong xi yi jie he za zhi = Chinese journal of modern developments in traditional medicine, 1986, Volume: 6, Issue:7

    Topics: Adolescent; Adult; Child; Female; Finger Injuries; Gentamicins; Humans; Male; Medicine, Chinese Trad

1986
Bacillus cereus endophthalmitis.
    Canadian journal of surgery. Journal canadien de chirurgie, 1987, Volume: 30, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Bacillus cereus; Bacterial Infections; Clindamycin; Endophthalmitis; E

1987
[A new approach in the complex treatment of open injuries].
    Klinicheskaia khirurgiia, 1986, Issue:4

    Topics: Administration, Topical; Adult; Anti-Infective Agents, Local; Bandages; Gentamicins; Humans; Male; P

1986