Page last updated: 2024-10-27

gentamicin and Wounds, Gunshot

gentamicin has been researched along with Wounds, Gunshot in 17 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Wounds, Gunshot: Disruption of structural continuity of the body as a result of the discharge of firearms.

Research Excerpts

ExcerptRelevanceReference
"Management to prevent cervical osteomyelitis in transpharyngeal gunshot wounds which involve the cervical spine consists of triple endoscopy to identify the pharyngeal injury, anteroposterior and lateral view roentgenograms to localize the injury to the cervical spine, administration of penicillin and gentamicin intravenously, exploration of the neck and repair of pharyngeal wounds, debridement of the cervical spine and external immobilization of the spine for six weeks."3.66The management of transpharyngeal gunshot wounds to the cervical spine. ( Bucholz, RW; Carder, HM; Jones, RE; Schaefer, SD, 1981)
"Aztreonam was administered at a dosage of 2 g every 8 hours and gentamicin at 5 mg/kg for the first 24 hours and then adjusted by serum monitoring to a peak of 6 to 8 micrograms/mL and a trough of less than 2 micrograms/mL; all patients received 900 mg of clindamycin every 8 hours."2.67Superiority of aztreonam/clindamycin compared with gentamicin/clindamycin in patients with penetrating abdominal trauma. ( Boucher, BA; Charland, SL; Croce, MA; Fabian, TC; Hess, MM; Rodman, JH; Wilson, RS; Wilson, SE, 1994)
"In 41% of all patients operative treatment for osteomyelitis was necessary (37% sequesterectomies, 44% stabilisations with fixateur externe)."1.28[Treatment of osteomyelitis and reconstructive measures in patients with war injuries]. ( Bartsch, C; Peters, KM; Zilkens, KW, 1992)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19908 (47.06)18.7374
1990's8 (47.06)18.2507
2000's1 (5.88)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balseris, S1
Einoriene, D1
Martinkenas, JL1
Tolocka, R1
Asche, G1
Mandal, AK3
Thadepalli, H3
Matory, E1
Lou, MA2
O'Donnell, VA1
Schaefer, SD1
Bucholz, RW1
Jones, RE1
Carder, HM1
Lin, SS1
Vaccaro, AR1
Reisch, S1
Devine, M1
Cotler, JM1
Reich, SM1
Fabian, TC1
Hess, MM1
Croce, MA1
Wilson, RS1
Wilson, SE1
Charland, SL1
Rodman, JH1
Boucher, BA1
Knapp, TP1
Patzakis, MJ2
Lee, J1
Seipel, PR1
Abdollahi, K1
Reisch, RB1
O'Donnell, V1
Lou, SM1
Wilson, TH1
Lucas, JW1
Georgen, GJ1
Monaco, F1
Dorr, LD1
Ivler, D1
Moore, TM1
Harvey, JP1
Peters, KM1
Zilkens, KW1
Bartsch, C1
Kolodziejczyk, D1
Hirsch, WD1
Shaposhnikov, IuG1
Kaveshnikov, AI1
Kroĭtor, GM1
Okropiridze, GG1
Lipkin, SI1
Cziffer, E1
Farkas, J1
Turchányi, B1
Prabhala, RH1
Saad, AF1
Farrar, WE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Operative and Non-operative Treatment of Traumatic Arthrotomies: A Prospective Observational Study[NCT02841644]180 participants (Actual)Observational2015-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Complications

Complications were defined as septic arthritis, return to the OR, rehospitalization, and osteomyelitis of the injured joint. (NCT02841644)
Timeframe: 12 months

InterventionParticipants (Count of Participants)
Traumatic Arthrotomy- Treated Nonoperatively4
Traumatic Arthrotomy- Treated Operatively18

Cost of Treatments

To compare the cost of medical care in patients with traumatic arthrotomies treated with surgical irrigation and debridement versus non-operative treatment with local wound care. To estimate cost associated with TAs, total charge data was acquired for all patients treated at the lead site. (NCT02841644)
Timeframe: 12 months

InterventionUSD (Median)
Traumatic Arthrotomy- Treated Nonoperatively1089
Traumatic Arthrotomy- Treated Operatively11,973

Comparing 3-Month Change in Veterans RAND 12-Item Health Survey (VR-12) by Treatment Method

The veteran rand 12-tem health survey is used to determine change in health related quality of life to estimate disease burden. It is summarized into two scores, a physical component scores (PCS) (range 0-100) and mental component scores (range- 0-100). Higher score indicate better outcomes. (NCT02841644)
Timeframe: baseline, 3 months

,
Interventionscore on a scale (Mean)
VR-12 Physical Health: BaselineVR-12 Mental Health: BaselineVR-12 Physical Health: 3 monthVR-12 Mental Health: 3 MonthVR-12 Physical Health: DifferenceVR-12 Mental Health: Difference
Traumatic Arthrotomy- Treated Nonoperatively4950.736.941.9-12.2-8.8
Traumatic Arthrotomy- Treated Operatively48.151.832.146.8-16.0-5.1

Reviews

2 reviews available for gentamicin and Wounds, Gunshot

ArticleYear
Low-velocity gunshot wounds to the spine with an associated transperitoneal injury.
    Journal of spinal disorders, 1995, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Antifungal Agents; Cefoxitin; Child; Colon; Discitis; Drug Therapy, Combination;

1995
Comparison of intravenous and oral antibiotic therapy in the treatment of fractures caused by low-velocity gunshots. A prospective, randomized study of infection rates.
    The Journal of bone and joint surgery. American volume, 1996, Volume: 78, Issue:8

    Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Cephalosporin

1996

Trials

2 trials available for gentamicin and Wounds, Gunshot

ArticleYear
Superiority of aztreonam/clindamycin compared with gentamicin/clindamycin in patients with penetrating abdominal trauma.
    American journal of surgery, 1994, Volume: 167, Issue:3

    Topics: Abdominal Injuries; Adult; Aztreonam; Bacterial Infections; Blood Transfusion; Clindamycin; Colon; D

1994
Comparison of intravenous and oral antibiotic therapy in the treatment of fractures caused by low-velocity gunshots. A prospective, randomized study of infection rates.
    The Journal of bone and joint surgery. American volume, 1996, Volume: 78, Issue:8

    Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Cephalosporin

1996

Other Studies

14 other studies available for gentamicin and Wounds, Gunshot

ArticleYear
Sinoorbital gunshot injuries. Endoscopic diagnostics and management.
    Medicina (Kaunas, Lithuania), 2008, Volume: 44, Issue:4

    Topics: Anti-Bacterial Agents; Debridement; Endoscopy; Foreign Bodies; Gentamicins; Humans; Image Processing

2008
[Treatment and treatment results of infections of the hand with gentamicin PMMA minichains].
    Zentralblatt fur Chirurgie, 1983, Volume: 108, Issue:11

    Topics: Adult; Female; Fracture Fixation, Internal; Fractures, Bone; Gentamicins; Hand Injuries; Humans; Mal

1983
Evaluation of antibiotic therapy and surgical techniques in cases of homicidal wounds of the colon.
    The American surgeon, 1984, Volume: 50, Issue:5

    Topics: Anti-Bacterial Agents; Bacterial Infections; Carbenicillin; Cephalothin; Clindamycin; Colon; Colosto

1984
The management of transpharyngeal gunshot wounds to the cervical spine.
    Surgery, gynecology & obstetrics, 1981, Volume: 152, Issue:1

    Topics: Cervical Vertebrae; Endoscopy; Gentamicins; Humans; Male; Osteomyelitis; Penicillins; Pharynx; Radio

1981
Evaluation of carbenicillin and a comparison of clindamycin and gentamicin combined therapy in penetrating abdominal trauma.
    Surgery, gynecology & obstetrics, 1978, Volume: 147, Issue:4

    Topics: Abdominal Injuries; Adolescent; Adult; Aerobiosis; Aminoglycosides; Anaerobiosis; Bacterial Infectio

1978
Penetrating trauma of colon, cava, and cord.
    The Journal of trauma, 1976, Volume: 16, Issue:5

    Topics: Abdominal Injuries; Adult; Ampicillin; Chloramphenicol; Colon; Escherichia coli Infections; Gentamic

1976
Management of shotgun wound of the symphysis.
    Journal of oral surgery (American Dental Association : 1965), 1975, Volume: 33, Issue:8

    Topics: Bone Plates; Chromium Alloys; Dental Implantation; Gentamicins; Humans; Ilium; Male; Mandible; Mandi

1975
The early management of open joint injuries. A prospective study of one hundred and forty patients.
    The Journal of bone and joint surgery. American volume, 1975, Volume: 57, Issue:8

    Topics: Adult; Aged; Ankle Injuries; Drainage; Female; Femoral Fractures; Fractures, Bone; Gentamicins; Huma

1975
[Treatment of osteomyelitis and reconstructive measures in patients with war injuries].
    Aktuelle Traumatologie, 1992, Volume: 22, Issue:2

    Topics: Adult; Amputation, Surgical; Blast Injuries; Bone Transplantation; Foreign Bodies; Fracture Fixation

1992
[Epidural "sulmycin implant" coverage for local prevention of infection in surgical management of open craniocerebral injuries].
    Aktuelle Traumatologie, 1992, Volume: 22, Issue:6

    Topics: Adolescent; Adult; Aged; Brain Injuries; Child; Child, Preschool; Craniotomy; Drug Implants; Female;

1992
[Experimental substantiation of using gentacycol for prevention of wound infection in gunshot bone fractures of the extremities].
    Ortopediia travmatologiia i protezirovanie, 1991, Issue:6

    Topics: Animals; Arm Injuries; Bacterial Infections; Disease Models, Animal; Dogs; Drug Evaluation, Preclini

1991
Management of potentially infected complex hand injuries.
    The Journal of hand surgery, 1991, Volume: 16, Issue:5

    Topics: Adult; Bone Transplantation; External Fixators; Finger Injuries; Gentamicins; Hand Injuries; Humans;

1991
Human intestinal tissue antibiotic concentrations. Clindamycin, gentamicin, and mezlocillin.
    The American surgeon, 1990, Volume: 56, Issue:11

    Topics: Adult; Ascitic Fluid; Bacterial Infections; Clindamycin; Drug Administration Schedule; Drug Evaluati

1990
Intracisternal and intrathecal injections of gentamicin in enterobacter meningitis.
    Archives of internal medicine, 1974, Volume: 134, Issue:4

    Topics: Adult; Cisterna Magna; Enterobacteriaceae Infections; Gentamicins; Humans; Injections; Injections, I

1974