gentamicin has been researched along with Wounds, Gunshot in 17 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Wounds, Gunshot: Disruption of structural continuity of the body as a result of the discharge of firearms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Management to prevent cervical osteomyelitis in transpharyngeal gunshot wounds which involve the cervical spine consists of triple endoscopy to identify the pharyngeal injury, anteroposterior and lateral view roentgenograms to localize the injury to the cervical spine, administration of penicillin and gentamicin intravenously, exploration of the neck and repair of pharyngeal wounds, debridement of the cervical spine and external immobilization of the spine for six weeks." | 3.66 | The management of transpharyngeal gunshot wounds to the cervical spine. ( Bucholz, RW; Carder, HM; Jones, RE; Schaefer, SD, 1981) |
| "Aztreonam was administered at a dosage of 2 g every 8 hours and gentamicin at 5 mg/kg for the first 24 hours and then adjusted by serum monitoring to a peak of 6 to 8 micrograms/mL and a trough of less than 2 micrograms/mL; all patients received 900 mg of clindamycin every 8 hours." | 2.67 | Superiority of aztreonam/clindamycin compared with gentamicin/clindamycin in patients with penetrating abdominal trauma. ( Boucher, BA; Charland, SL; Croce, MA; Fabian, TC; Hess, MM; Rodman, JH; Wilson, RS; Wilson, SE, 1994) |
| "In 41% of all patients operative treatment for osteomyelitis was necessary (37% sequesterectomies, 44% stabilisations with fixateur externe)." | 1.28 | [Treatment of osteomyelitis and reconstructive measures in patients with war injuries]. ( Bartsch, C; Peters, KM; Zilkens, KW, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (47.06) | 18.7374 |
| 1990's | 8 (47.06) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Balseris, S | 1 |
| Einoriene, D | 1 |
| Martinkenas, JL | 1 |
| Tolocka, R | 1 |
| Asche, G | 1 |
| Mandal, AK | 3 |
| Thadepalli, H | 3 |
| Matory, E | 1 |
| Lou, MA | 2 |
| O'Donnell, VA | 1 |
| Schaefer, SD | 1 |
| Bucholz, RW | 1 |
| Jones, RE | 1 |
| Carder, HM | 1 |
| Lin, SS | 1 |
| Vaccaro, AR | 1 |
| Reisch, S | 1 |
| Devine, M | 1 |
| Cotler, JM | 1 |
| Reich, SM | 1 |
| Fabian, TC | 1 |
| Hess, MM | 1 |
| Croce, MA | 1 |
| Wilson, RS | 1 |
| Wilson, SE | 1 |
| Charland, SL | 1 |
| Rodman, JH | 1 |
| Boucher, BA | 1 |
| Knapp, TP | 1 |
| Patzakis, MJ | 2 |
| Lee, J | 1 |
| Seipel, PR | 1 |
| Abdollahi, K | 1 |
| Reisch, RB | 1 |
| O'Donnell, V | 1 |
| Lou, SM | 1 |
| Wilson, TH | 1 |
| Lucas, JW | 1 |
| Georgen, GJ | 1 |
| Monaco, F | 1 |
| Dorr, LD | 1 |
| Ivler, D | 1 |
| Moore, TM | 1 |
| Harvey, JP | 1 |
| Peters, KM | 1 |
| Zilkens, KW | 1 |
| Bartsch, C | 1 |
| Kolodziejczyk, D | 1 |
| Hirsch, WD | 1 |
| Shaposhnikov, IuG | 1 |
| Kaveshnikov, AI | 1 |
| Kroĭtor, GM | 1 |
| Okropiridze, GG | 1 |
| Lipkin, SI | 1 |
| Cziffer, E | 1 |
| Farkas, J | 1 |
| Turchányi, B | 1 |
| Prabhala, RH | 1 |
| Saad, AF | 1 |
| Farrar, WE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Operative and Non-operative Treatment of Traumatic Arthrotomies: A Prospective Observational Study[NCT02841644] | 180 participants (Actual) | Observational | 2015-04-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Complications were defined as septic arthritis, return to the OR, rehospitalization, and osteomyelitis of the injured joint. (NCT02841644)
Timeframe: 12 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Traumatic Arthrotomy- Treated Nonoperatively | 4 |
| Traumatic Arthrotomy- Treated Operatively | 18 |
To compare the cost of medical care in patients with traumatic arthrotomies treated with surgical irrigation and debridement versus non-operative treatment with local wound care. To estimate cost associated with TAs, total charge data was acquired for all patients treated at the lead site. (NCT02841644)
Timeframe: 12 months
| Intervention | USD (Median) |
|---|---|
| Traumatic Arthrotomy- Treated Nonoperatively | 1089 |
| Traumatic Arthrotomy- Treated Operatively | 11,973 |
The veteran rand 12-tem health survey is used to determine change in health related quality of life to estimate disease burden. It is summarized into two scores, a physical component scores (PCS) (range 0-100) and mental component scores (range- 0-100). Higher score indicate better outcomes. (NCT02841644)
Timeframe: baseline, 3 months
| Intervention | score on a scale (Mean) | |||||
|---|---|---|---|---|---|---|
| VR-12 Physical Health: Baseline | VR-12 Mental Health: Baseline | VR-12 Physical Health: 3 month | VR-12 Mental Health: 3 Month | VR-12 Physical Health: Difference | VR-12 Mental Health: Difference | |
| Traumatic Arthrotomy- Treated Nonoperatively | 49 | 50.7 | 36.9 | 41.9 | -12.2 | -8.8 |
| Traumatic Arthrotomy- Treated Operatively | 48.1 | 51.8 | 32.1 | 46.8 | -16.0 | -5.1 |
2 reviews available for gentamicin and Wounds, Gunshot
| Article | Year |
|---|---|
Low-velocity gunshot wounds to the spine with an associated transperitoneal injury.
Topics: Adolescent; Adult; Antifungal Agents; Cefoxitin; Child; Colon; Discitis; Drug Therapy, Combination; | 1995 |
Comparison of intravenous and oral antibiotic therapy in the treatment of fractures caused by low-velocity gunshots. A prospective, randomized study of infection rates.
Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Cephalosporin | 1996 |
2 trials available for gentamicin and Wounds, Gunshot
| Article | Year |
|---|---|
Superiority of aztreonam/clindamycin compared with gentamicin/clindamycin in patients with penetrating abdominal trauma.
Topics: Abdominal Injuries; Adult; Aztreonam; Bacterial Infections; Blood Transfusion; Clindamycin; Colon; D | 1994 |
Comparison of intravenous and oral antibiotic therapy in the treatment of fractures caused by low-velocity gunshots. A prospective, randomized study of infection rates.
Topics: Administration, Oral; Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Cephalosporin | 1996 |
14 other studies available for gentamicin and Wounds, Gunshot
| Article | Year |
|---|---|
Sinoorbital gunshot injuries. Endoscopic diagnostics and management.
Topics: Anti-Bacterial Agents; Debridement; Endoscopy; Foreign Bodies; Gentamicins; Humans; Image Processing | 2008 |
[Treatment and treatment results of infections of the hand with gentamicin PMMA minichains].
Topics: Adult; Female; Fracture Fixation, Internal; Fractures, Bone; Gentamicins; Hand Injuries; Humans; Mal | 1983 |
Evaluation of antibiotic therapy and surgical techniques in cases of homicidal wounds of the colon.
Topics: Anti-Bacterial Agents; Bacterial Infections; Carbenicillin; Cephalothin; Clindamycin; Colon; Colosto | 1984 |
The management of transpharyngeal gunshot wounds to the cervical spine.
Topics: Cervical Vertebrae; Endoscopy; Gentamicins; Humans; Male; Osteomyelitis; Penicillins; Pharynx; Radio | 1981 |
Evaluation of carbenicillin and a comparison of clindamycin and gentamicin combined therapy in penetrating abdominal trauma.
Topics: Abdominal Injuries; Adolescent; Adult; Aerobiosis; Aminoglycosides; Anaerobiosis; Bacterial Infectio | 1978 |
Penetrating trauma of colon, cava, and cord.
Topics: Abdominal Injuries; Adult; Ampicillin; Chloramphenicol; Colon; Escherichia coli Infections; Gentamic | 1976 |
Management of shotgun wound of the symphysis.
Topics: Bone Plates; Chromium Alloys; Dental Implantation; Gentamicins; Humans; Ilium; Male; Mandible; Mandi | 1975 |
The early management of open joint injuries. A prospective study of one hundred and forty patients.
Topics: Adult; Aged; Ankle Injuries; Drainage; Female; Femoral Fractures; Fractures, Bone; Gentamicins; Huma | 1975 |
[Treatment of osteomyelitis and reconstructive measures in patients with war injuries].
Topics: Adult; Amputation, Surgical; Blast Injuries; Bone Transplantation; Foreign Bodies; Fracture Fixation | 1992 |
[Epidural "sulmycin implant" coverage for local prevention of infection in surgical management of open craniocerebral injuries].
Topics: Adolescent; Adult; Aged; Brain Injuries; Child; Child, Preschool; Craniotomy; Drug Implants; Female; | 1992 |
[Experimental substantiation of using gentacycol for prevention of wound infection in gunshot bone fractures of the extremities].
Topics: Animals; Arm Injuries; Bacterial Infections; Disease Models, Animal; Dogs; Drug Evaluation, Preclini | 1991 |
Management of potentially infected complex hand injuries.
Topics: Adult; Bone Transplantation; External Fixators; Finger Injuries; Gentamicins; Hand Injuries; Humans; | 1991 |
Human intestinal tissue antibiotic concentrations. Clindamycin, gentamicin, and mezlocillin.
Topics: Adult; Ascitic Fluid; Bacterial Infections; Clindamycin; Drug Administration Schedule; Drug Evaluati | 1990 |
Intracisternal and intrathecal injections of gentamicin in enterobacter meningitis.
Topics: Adult; Cisterna Magna; Enterobacteriaceae Infections; Gentamicins; Humans; Injections; Injections, I | 1974 |