gentamicin has been researched along with Vertigo in 156 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Vertigo: An illusion of movement, either of the external world revolving around the individual or of the individual revolving in space. Vertigo may be associated with disorders of the inner ear (EAR, INNER); VESTIBULAR NERVE; BRAINSTEM; or CEREBRAL CORTEX. Lesions in the TEMPORAL LOBE and PARIETAL LOBE may be associated with FOCAL SEIZURES that may feature vertigo as an ictal manifestation. (From Adams et al., Principles of Neurology, 6th ed, pp300-1)
Excerpt | Relevance | Reference |
---|---|---|
"Intratympanic application of gentamicin is a relatively safe and efficient treatment for the reduction of complaints of vertigo attacks associated with Menière's disease." | 9.13 | Intratympanic gentamicin therapy for control of vertigo in unilateral Menire's disease: a prospective, double-blind, randomized, placebo-controlled trial. ( Albers, FW; Kingma, CM; Postema, RJ; Van Der Laan, BF; Wit, HP, 2008) |
" Intratympanic gentamicin (ITG) was superior to intratympanic steroid (ITS) in reducing the number of vertigo attacks (odds ratio (OR) 3." | 9.12 | What is the efficacy of gentamicin on the incidence of vertigo attacks and hearing in patients with Meniere's disease compared with steroids? A meta-analysis. ( Jiang, M; Zhang, Z; Zhao, C, 2021) |
"We investigated the effect of intratympanic gentamicin and dexamethasone treatments on the control of vertigo and hearing loss in patients with Meniere's disease." | 9.12 | [Intratympanic treatment in Meniere's disease: the effect of gentamicin and dexamethasone on vertigo control and hearing]. ( Akkuzu, B; Ozgirgin, N; Ozlüoğlu, LN, 2006) |
"To determine if a protocol of weekly intratympanic gentamicin injections administered until development of signs of unilateral vestibular hypofunction can alleviate vertigo while preserving hearing in patients with intractable vertigo caused by unilateral Meniere's disease." | 9.09 | Intratympanic gentamicin for control of vertigo in Meniere's disease: vestibular signs that specify completion of therapy. ( Minor, LB, 1999) |
"To assess the effectiveness of intratympanic gentamicin in the treatment of vertigo in Ménière's disease." | 8.87 | Intratympanic gentamicin for Ménière's disease or syndrome. ( Pullens, B; van Benthem, PP, 2011) |
"Titration therapy with intratympanic gentamicin offers class A or B control of vertigo in 87% (range, 75%-100%) of patients with unilateral Ménière's disease." | 8.82 | Intratympanic gentamicin for the treatment of Meniere's disease and other forms of peripheral vertigo. ( Carey, J, 2004) |
"To describe the long-term clinical vertigo control along with measured lateral canal vestibular function in patients with unilateral refractory Menière's disease (MD) treated with gentamicin transtympanic injections (TTI)." | 7.91 | Long-term Vertigo Control and Vestibular Function After Low-dose On-demand Transtympanic Gentamicin for Refractory Menière's Disease. ( Deguine, O; Fraysse, B; Fraysse, ME; Kmeid, M; Mansour, C; Marx, M; Nicolas, S, 2019) |
"To evaluate the objective and subjective effects of intratympanic gentamicin treatment in patients with small vestibular schwannomas who exhibit intractable vertigo." | 7.88 | Intratympanic Gentamicin for Small Vestibular Schwannomas With Intractable Vertigo. ( Huang, M; Jia, H; Li, G; Li, Y; Wang, Z; Wu, H; Yang, J; Zhu, W, 2018) |
"To document the effect of intratympanic gentamicin as treatment of disabling vertigo secondary to a vestibular schwannoma in elderly patients." | 7.79 | The use of intratympanic gentamicin in patients with vestibular schwannoma and disabling vertigo. ( Falcioni, M; Giannuzzi, AL; Merkus, P, 2013) |
"To compare the cochlear distribution of low-dose fluorescent gentamicin after intra-tympanic administration in guinea pig (GPs) with clinical data of low dose intra-tympanic gentamicin in patients with intractable vertigo." | 7.76 | Evidence-based modification of intratympanic gentamicin injections in patients with intractable vertigo. ( Dai, CF; Liu, JP; Steyger, PS; Wang, Q; Zhai, F, 2010) |
"To compare proportions of the combined outcome of vertigo control and hearing preservation between intratympanic gentamicin injections and endolymphatic sac shunt surgery for intractable vertigo in Ménière's disease patients." | 7.76 | Outcomes of endolymphatic shunt surgery for Ménière's disease: comparison with intratympanic gentamicin on vertigo control and hearing loss. ( Berliner, K; Chung, J; Derebery, MJ; Fisher, LM; Green, K, 2010) |
"The aim of this study was to correlate long-term vertigo control with reduction in vestibular function after intratympanic (IT) gentamicin therapy for unilateral Ménière's disease." | 7.75 | Vestibular function and vertigo control after intratympanic gentamicin for Ménière's disease. ( Carey, JP; Della Santina, CC; Minor, LB; Nguyen, KD, 2009) |
"To assess long-term vertigo symptom control in patients after intratympanic gentamicin instillation for incapacitating unilateral Ménière's disease." | 7.74 | Long-term vertigo control in patients after intratympanic gentamicin instillation for Ménière's disease. ( Alexander, A; Bodmer, D; Chen, JM; Morong, S; Nedzelski, JM; Stewart, C, 2007) |
"This retrospective study reports the overall efficacy and comparative results of intratympanic gentamicin injections for disabling vertigo episodes." | 7.74 | Gentamicin injections for Ménière disease: comparison of subjective and objective end points. ( Cronin, GW; Hardin, RB; Steenerson, RL, 2008) |
"To look for factors relating to the vertigo control and hearing changes after intratympanic injections of gentamicin (GM)." | 7.73 | Factors relating to the vertigo control and hearing changes following intratympanic gentamicin for intractable Ménière's disease. ( Fukushima, M; Horii, A; Kitahara, T; Kizawa, K; Kubo, T; Masumura, C; Mitani, K; Nakagawa, A; Nishiike, S; Nishimura, M; Saika, T; Sasaki, T; Uno, A, 2006) |
"The objective of our study was to determine whether angular vestibulo-ocular reflex (aVOR) gains correlated with vertigo control after intratympanic gentamicin treatment for Meniere's disease." | 7.73 | Angular vestibulo-ocular reflex gains correlate with vertigo control after intratympanic gentamicin treatment for Meniere's disease. ( Carey, JP; Haslwanter, T; Lin, FR; Migliaccio, AA; Minor, LB, 2005) |
"Treatment of drop attacks is still a matter of discussion; most cases have a benign course with spontaneous remission and no treatment is necessary." | 5.33 | Drop attacks and vertical vertigo after transtympanic gentamicin: diagnosis and management. ( Bignami, M; Bruschini, L; Casani, AP; Dallan, I; Nacci, A, 2005) |
"Of these, 68 patients had Meniere's disease; 4 patients had recurrent vertigo after endolymphatic sac surgery and were followed for at least 1 year." | 5.31 | Intratympanic gentamicin therapy for persistent vertigo after endolymphatic sac surgery. ( Leonetti, JP; Marzo, SJ, 2002) |
" We concluded that intratympanic gentamicin may improve the control of vertigo, and result in little or no difference to tinnitus, but the certainty of the evidence is low." | 5.22 | Intratympanic gentamicin compared with placebo for Ménière's disease. ( de Amesti, F; Santander, MJ; Winter, M, 2022) |
"Background The intratympanic application of the ototoxic aminoglycoside gentamicin has shown promising results as an ablative treatment for vertigo associated with Ménière's disease." | 5.22 | The effect of intratympanic gentamicin for treatment of Ménière's disease on lower frequency hearing. ( Becker, M; Chung, DW; Sam, G; van der Hoeven, R; Verweij, S, 2016) |
"Intratympanic application of gentamicin is a relatively safe and efficient treatment for the reduction of complaints of vertigo attacks associated with Menière's disease." | 5.13 | Intratympanic gentamicin therapy for control of vertigo in unilateral Menire's disease: a prospective, double-blind, randomized, placebo-controlled trial. ( Albers, FW; Kingma, CM; Postema, RJ; Van Der Laan, BF; Wit, HP, 2008) |
" Intratympanic gentamicin (ITG) was superior to intratympanic steroid (ITS) in reducing the number of vertigo attacks (odds ratio (OR) 3." | 5.12 | What is the efficacy of gentamicin on the incidence of vertigo attacks and hearing in patients with Meniere's disease compared with steroids? A meta-analysis. ( Jiang, M; Zhang, Z; Zhao, C, 2021) |
"We investigated the effect of intratympanic gentamicin and dexamethasone treatments on the control of vertigo and hearing loss in patients with Meniere's disease." | 5.12 | [Intratympanic treatment in Meniere's disease: the effect of gentamicin and dexamethasone on vertigo control and hearing]. ( Akkuzu, B; Ozgirgin, N; Ozlüoğlu, LN, 2006) |
"To determine if a protocol of weekly intratympanic gentamicin injections administered until development of signs of unilateral vestibular hypofunction can alleviate vertigo while preserving hearing in patients with intractable vertigo caused by unilateral Meniere's disease." | 5.09 | Intratympanic gentamicin for control of vertigo in Meniere's disease: vestibular signs that specify completion of therapy. ( Minor, LB, 1999) |
"We evaluated the hypothesis that topical intratympanic gentamicin can relieve the vertigo of disabling Menière's disease, reduce or ablate vestibular caloric excitability, and preserve hearing." | 5.07 | Treatment of Menière's disease with topical gentamicin: a preliminary report. ( Bryce, GE; Nedzelski, JM; Pfleiderer, AG, 1992) |
"To assess the effectiveness of intratympanic gentamicin in the treatment of vertigo in Ménière's disease." | 4.87 | Intratympanic gentamicin for Ménière's disease or syndrome. ( Pullens, B; van Benthem, PP, 2011) |
"To assess and summarize the best available evidence for the use of intratympanic gentamicin in patients with Meniere's disease with respect to improvement of vertigo, tinnitus, and change in hearing." | 4.82 | Systematic review of intratympanic gentamicin in Meniere's disease. ( Diamond, C; Hornig, JD; Liu, R; O'Connell, DA, 2003) |
"Titration therapy with intratympanic gentamicin offers class A or B control of vertigo in 87% (range, 75%-100%) of patients with unilateral Ménière's disease." | 4.82 | Intratympanic gentamicin for the treatment of Meniere's disease and other forms of peripheral vertigo. ( Carey, J, 2004) |
"Inclusion criteria to select articles for meta-analysis were clear description of gentamicin delivery technique, clearly reported vertigo control results, and report of hearing loss posttreatment." | 4.82 | Intratympanic gentamicin therapy for Ménière's disease: a meta-analysis. ( Anderson, JP; Chia, SH; Gamst, AC; Harris, JP, 2004) |
"At least 11 articles have been published that indicate that intratympanic gentamicin treatments control vertigo well and provide acceptable rates of hearing loss." | 4.79 | Clinical forum: a review of intratympanic therapy. ( Blakley, BW, 1997) |
"Ménière's disease (MD), characterized by episodic vertigo attacks and fluctuating progressive hearing loss, is treated by low-dose intratympanic gentamicin (ITG) injections." | 4.02 | Intratympanic gentamicin injection for refractory ménière's disease (MD) has potential effect in preventing contralateral MD occurrence. ( Dai, C; Song, Z; Wang, J; Wu, Y; Yu, J; Zhou, Y, 2021) |
"To describe the long-term clinical vertigo control along with measured lateral canal vestibular function in patients with unilateral refractory Menière's disease (MD) treated with gentamicin transtympanic injections (TTI)." | 3.91 | Long-term Vertigo Control and Vestibular Function After Low-dose On-demand Transtympanic Gentamicin for Refractory Menière's Disease. ( Deguine, O; Fraysse, B; Fraysse, ME; Kmeid, M; Mansour, C; Marx, M; Nicolas, S, 2019) |
"To determine whether long term (>48 months) symptomatic vertigo control is sustained in patients with Menière's disease from a previous comparative trial of intratympanic methylprednisolone versus gentamicin, and if the two treatments remain nonsignificantly different at long-term follow-up." | 3.91 | Long-Term Follow-Up of Intratympanic Methylprednisolone Versus Gentamicin in Patients With Unilateral Menière's Disease. ( Agarwal, K; Bronstein, AM; Golding, JF; Harcourt, JP; Lambert, A; Patel, M; Wong, PY, 2019) |
"In the last 4 years the authors observed a trend that correcting vitamin D deficiency in newly diagnosed cases of Meniere's disease decreased the necessity of the ablative therapy with intratympanic gentamicin." | 3.88 | Vitamin D supplementation may improve symptoms in Meniere's disease. ( Büki, B; Jünger, H; Lundberg, YW, 2018) |
"To evaluate the objective and subjective effects of intratympanic gentamicin treatment in patients with small vestibular schwannomas who exhibit intractable vertigo." | 3.88 | Intratympanic Gentamicin for Small Vestibular Schwannomas With Intractable Vertigo. ( Huang, M; Jia, H; Li, G; Li, Y; Wang, Z; Wu, H; Yang, J; Zhu, W, 2018) |
"To compare the efficacy of intratympanic gentamicin injection (ITG) on vertigo control, drop attacks, and functional level in Menière's disease patients with and without a history of migraine." | 3.85 | Efficacy of Intratympanic Gentamicin in Menière's Disease With and Without Migraine. ( Liu, YF; Rauch, SD; Renk, E; Xu, HX, 2017) |
" Further repeated ITD courses or intratympanic gentamicin (ITG) were given if the vertigo was not satisfactorily controlled." | 3.83 | Intratympanic steroids injection is effective for the treatment of drop attacks with Ménière's disease and delayed endolymphatic hydrops: A retrospective study. ( Kong, WJ; Leng, Y; Liu, B; Liu, D; Liu, J; Zhang, SL; Zhou, R, 2016) |
"1) To evaluate the efficacy of, and problems with, intratympanic gentamicin injection (ITG) in medically intractable definite Ménière's disease (MD) and secondary endolymphatic hydrops (EH); and 2) to review the vestibular status and treatment options of intractable vertigo even after ITG." | 3.81 | Management of intractable Ménière's disease after intratympanic injection of gentamicin. ( Choi, BY; Han, JJ; Koo, JW; Park, J; Rah, YC, 2015) |
" Moreover, intratympanic gentamicin injection (ITG), as a chemical labyrinthectomy, is a simple alternative for controlling vertigo in patients with ipsilateral DEH." | 3.81 | Intratympanic injection in delayed endolymphatic hydrops. ( Kong, W; Leng, Y; Liu, B; Liu, J; Zhang, S; Zhou, R, 2015) |
"In recent years, several titration or on-demand protocols using low-dose repeated intratympanic (IT) gentamicin injections have been adopted for the vertigo control in unilateral medical refractory Menière's disease (MD)." | 3.80 | Intratympanic gentamicin treatment 'as needed' for Meniere's disease. Long-term analysis using the Kaplan-Meier method. ( Benazzo, M; Gatti, O; Manfrin, M; Mira, E; Quaglieri, S; Rebecchi, E; Tinelli, C, 2014) |
"A 79-year-old male, with bilateral loss of vestibular function caused by gentamicin toxicity after surgery for prosthetic valve endocarditis, complained of dizziness, difficulty in walking and an increased risk of falling." | 3.80 | Treatment of vertigo and postural instability using visual illusions. ( De Ru, JA; Mert, A; van Kerckhoven, G, 2014) |
"To document the effect of intratympanic gentamicin as treatment of disabling vertigo secondary to a vestibular schwannoma in elderly patients." | 3.79 | The use of intratympanic gentamicin in patients with vestibular schwannoma and disabling vertigo. ( Falcioni, M; Giannuzzi, AL; Merkus, P, 2013) |
"To compare the cochlear distribution of low-dose fluorescent gentamicin after intra-tympanic administration in guinea pig (GPs) with clinical data of low dose intra-tympanic gentamicin in patients with intractable vertigo." | 3.76 | Evidence-based modification of intratympanic gentamicin injections in patients with intractable vertigo. ( Dai, CF; Liu, JP; Steyger, PS; Wang, Q; Zhai, F, 2010) |
"Patients with stage 1 Ménière's disease appear to have similar vertigo control with better hearing preservation than patients with advanced disease when treated with low-dose intratympanic gentamicin (10 mg/mL)." | 3.76 | Intratympanic gentamicin treatment of patients with Ménière's disease with normal hearing. ( Alameda, YA; Daugherty, J; Silverstein, H; Van Ess, MJ; Wazen, J, 2010) |
"To compare proportions of the combined outcome of vertigo control and hearing preservation between intratympanic gentamicin injections and endolymphatic sac shunt surgery for intractable vertigo in Ménière's disease patients." | 3.76 | Outcomes of endolymphatic shunt surgery for Ménière's disease: comparison with intratympanic gentamicin on vertigo control and hearing loss. ( Berliner, K; Chung, J; Derebery, MJ; Fisher, LM; Green, K, 2010) |
"The aim of this study was to correlate long-term vertigo control with reduction in vestibular function after intratympanic (IT) gentamicin therapy for unilateral Ménière's disease." | 3.75 | Vestibular function and vertigo control after intratympanic gentamicin for Ménière's disease. ( Carey, JP; Della Santina, CC; Minor, LB; Nguyen, KD, 2009) |
"Administration of high-dose gentamicin for intractable Meniere's disease appears to be effective in achieving long-term control of vertigo." | 3.75 | High-dose intratympanic gentamicin instillations for treatment of Meniere's disease: long-term results. ( Hsieh, LC; Ko, YC; Lin, HC; Lin, LH; Shu, MT; Tsai, HT, 2009) |
"In Ménière's disease (MD), when patients have incapacitating vertigo that is resistant to drug treatment, an intratympanic gentamicin application (ITG) is often proposed." | 3.75 | Tenotomy of the tensor tympani and stapedius tendons in Ménière's disease. ( De Valck, CF; Van de Heyning, PH; Van Rompaey, V; Wuyts, EL, 2009) |
"Intratympanic gentamicin perfusion provides effective control of vertigo in patients with Ménière's disease." | 3.75 | Hearing results following intratympanic gentamicin perfusion for Ménière's disease. ( Aidonis, I; Kyrodimos, E; Sismanis, A, 2009) |
"Transtympanic gentamicin therapy via the Silverstein MicroWick results in good vertigo control." | 3.75 | Transtympanic gentamicin treatment using Silverstein MicroWick in Ménière's disease patients: long term outcome. ( O'Sullivan, G; Srinivasan, VR; Suryanarayanan, R, 2009) |
"To assess long-term vertigo symptom control in patients after intratympanic gentamicin instillation for incapacitating unilateral Ménière's disease." | 3.74 | Long-term vertigo control in patients after intratympanic gentamicin instillation for Ménière's disease. ( Alexander, A; Bodmer, D; Chen, JM; Morong, S; Nedzelski, JM; Stewart, C, 2007) |
"To describe the histopathology and morphometry of the vestibular end organs from a 59-year-old Meniere's patient who underwent transmastoid labyrinthectomy for recurrent vertigo after failed intratympanic gentamicin." | 3.74 | Histopathology of the vestibular end organs after intratympanic gentamicin failure for Meniere's disease. ( Baloh, RW; Ishiyama, A; Ishiyama, G; Lopez, I, 2007) |
"This retrospective study reports the overall efficacy and comparative results of intratympanic gentamicin injections for disabling vertigo episodes." | 3.74 | Gentamicin injections for Ménière disease: comparison of subjective and objective end points. ( Cronin, GW; Hardin, RB; Steenerson, RL, 2008) |
"Gentamicin ototoxicity presents with gait imbalance and oscillopsia, but only rarely with hearing loss and vertigo." | 3.73 | Gentamicin ototoxicity: clinical features and the effect on the human vestibulo-ocular reflex. ( Baloh, RW; Ishiyama, A; Ishiyama, G; Kerber, K, 2006) |
"Intratympanic gentamicin treatment ought to be offered to Ménière's patients suffering from disabling vertigo, with the proviso that they be made aware of the possibility of hearing deterioration." | 3.73 | Intratympanic gentamicin treatment in Meniere's disease: patients' experiences and outcomes. ( Prinsley, PR; Sandooram, D; Smith, WK, 2006) |
"The aim of this study was to verify the efficacy of a modified Odkvist titration protocol of intratympanic gentamicin application in the control of vertigo attacks and the effects on the auditory and vestibular function in a group of 71 patients affected by monolateral MD resistant to medical therapy." | 3.73 | Intratympanic gentamicin in monolateral Meniere's disease: our experience. ( Bertino, G; Casati, L; Durso, D; Manfrin, M; Mira, E, 2006) |
"To determine the long-term hearing and vestibular outcomes in patients with intractable vertigo caused by unilateral Meniere's disease, who were treated with transtympanic injection of gentamicin." | 3.73 | [Long-term results of transtympanic gentamicin treatment in Meniere's disease]. ( Bartoszewicz, R; Kowalska, M; Krzeska-Malinowska, I; Niemczyk, K; Pierchała, K, 2005) |
"The objective of our study was to determine whether angular vestibulo-ocular reflex (aVOR) gains correlated with vertigo control after intratympanic gentamicin treatment for Meniere's disease." | 3.73 | Angular vestibulo-ocular reflex gains correlate with vertigo control after intratympanic gentamicin treatment for Meniere's disease. ( Carey, JP; Haslwanter, T; Lin, FR; Migliaccio, AA; Minor, LB, 2005) |
"Interval treatment with up to three intratympanic gentamicin injections once weekly effectively controlled vertigo while preserving hearing in patients with Ménière's disease and recurrent or resistant vertigo after saccotomy." | 3.73 | Intratympanic gentamicin treatment after endolymphatic sac surgery. ( Gouveris, H; Lange, G; Mann, WJ, 2005) |
"To look for factors relating to the vertigo control and hearing changes after intratympanic injections of gentamicin (GM)." | 3.73 | Factors relating to the vertigo control and hearing changes following intratympanic gentamicin for intractable Ménière's disease. ( Fukushima, M; Horii, A; Kitahara, T; Kizawa, K; Kubo, T; Masumura, C; Mitani, K; Nakagawa, A; Nishiike, S; Nishimura, M; Saika, T; Sasaki, T; Uno, A, 2006) |
"To determine the long-term hearing outcome in patients with intractable vertigo caused by unilateral Ménière's disease who were treated with intratympanic injection of gentamicin." | 3.72 | Long-term hearing outcome in patients receiving intratympanic gentamicin for Ménière's disease. ( Minor, LB; Wu, IC, 2003) |
"Intratympanic gentamicin is an accepted mode of treatment for patients with Meniere's disease who suffer from recurrent vertigo attacks in spite of conservative medical treatment." | 3.72 | [Intratympanic gentamicin treatment for intractable Menière's disease]. ( Gilony, D; Kronenberg, J; Wolf, M, 2004) |
"To investigate the effect and toxicity of intratympanic gentamicin injection therapy for intractable vertigo of Menière's disease." | 3.72 | [Intratympanic gentamicin in Menière's disease]. ( Gao, B; Huang, W; Xu, H, 2004) |
"Transtympanic administration of gentamicin is reported to be a useful treatment for vertigo in such conditions as Meniere's disease, and determining appropriate clinical dosage of gentamicin is difficult." | 3.72 | Inner ear changes with intracochlear gentamicin administration in Guinea pigs. ( Okuda, T; Shimogori, H; Sugahara, K; Yamashita, H, 2004) |
"Vestibular nerve section and transtympanic gentamicin administration are procedures with proven efficacy in the treatment of vertigo associated with Meniere's disease refractory to medical management." | 3.72 | Vestibular nerve section versus intratympanic gentamicin for Meniere's disease. ( Arriaga, MA; Chen, DA; Hillman, TA, 2004) |
"It was concluded that increasing the gentamicin concentration to 40 mg/ml probably produces similar rates of vertigo control as those of the lower dose, at least initially, but requires fewer injections." | 3.71 | Efficacy of increased gentamicin concentration for intratympanic injection therapy in Ménière's disease. ( Abou-Halawa, AS; Poe, DS, 2002) |
"It appears that a single transtympanic gentamicin injection is effective in controlling the vertigo of Ménière's syndrome." | 3.71 | Long-term follow-up of transtympanic gentamicin for Ménière's syndrome. ( Beatty, CW; Driscoll, CL; Facer, GW; Harner, SG; McDonald, TJ, 2001) |
" There was no difference in general quality of life, present hearing loss, or tinnitus between the three treatment groups, but the gentamicin-treated patients had less vertigo than did the other groups." | 3.71 | Patients' subjective evaluations of quality of life related to disease-specific symptoms, sense of coherence, and treatment in Ménière's disease. ( Bagger-Sjöbäck, D; Bergenius, J; Langius, A; Söderman, AC; Tjell, C, 2001) |
"On the basis of an average 10-month follow-up period, of the methods currently available to treat Meniere's patients with gentamicin, low-flow CGT seems to provide an excellent combination of vertigo control and tinnitus and pressure improvement, with a relatively low risk to hearing and vestibular function." | 3.71 | Continuous gentamicin therapy using an IntraEAR microcatheter for Meniere's disease: a retrospective study. ( Seidman, M, 2002) |
"The vestibulotoxic effect of gentamicin is well documented; however, there is no general agreement on the gentamicin dose needed to control vertigo attacks without affecting the hearing." | 3.70 | Round window gentamicin mu-catheter--a new therapeutic tool in Ménière's disease. ( Charabi, S; Thomsen, J; Tos, M, 2000) |
"Intratympanic injections of a prepared gentamicin concentration of approximately 30 mg/ml were given weekly until the patient reported cessation of vertigo attacks." | 3.70 | Intratympanic gentamicin injection for the treatment of Meniere's disease. ( Poe, DS; Youssef, TF, 1998) |
"The subjective visual horizontal (SVH) was measured by means of a small, rotatable, luminous line in darkness in the upright head and body position and at 10, 20 and 30 degrees of tilt to the right and left before, and repeatedly during a follow-up period of 1 year after intratympanic gentamicin instillations in 12 patients with recurrent vertigo attacks." | 3.70 | Subjective visual horizontal during follow-up after unilateral vestibular deafferentation with gentamicin. ( Bergenius, J; Brantberg, K; Tribukait, A, 1998) |
"Vertigo frequency, hearing status, personal disability ratings, tinnitus level, and caloric responses before and after gentamicin therapy were measured." | 3.70 | Intratympanic gentamicin titration therapy for intractable Meniere's disease. ( Atlas, JT; Parnes, LS, 1999) |
"Intratympanic gentamicin therapy for vertigo in Meniere's disease was shown to be an effective treatment choice, as shown by our results." | 3.69 | Treatment of intractable Menière's disease with intratympanic gentamicin: review of the University of Ottawa experience. ( Corsten, M; Marsan, J; Robichaud, J; Schramm, D, 1997) |
"Adhering to the American Academy of Otolaryngology--Head and Neck Surgery 1985 criteria for reporting treatment results in Meniere's disease, the hearing status, control of vertigo, and disability scores using intratympanic gentamicin therapy were reported and compared with historical controls." | 3.69 | Intratympanic gentamicin therapy for Ménière's disease. ( Hirsch, BE; Kamerer, DB, 1997) |
"To control attacks of vertigo while preserving both hearing and labyrinthine function, low doses of gentamicin were instilled intratympanically in nine patients with intractable unilateral Meniere's disease." | 3.69 | Low-dose intratympanic gentamicin treatment of Menière's disease. ( Inoue, H; Nogami, K; Uchi, Y; Uemura, T, 1994) |
"To define better the benefits and risks of intratympanic gentamicin injection treatment of intractable vertigo or drop attacks due to Ménière's disease, we reviewed the charts of 18 patients whom we have now observed for > 1 year after having completed this mode of therapy." | 3.69 | Intratympanic gentamicin in Ménière's disease: results of therapy. ( Halmagyi, GM; Murofushi, T; Yavor, RA, 1997) |
"Gentamicin given as local therapy for severe Menière's disease is of considerable value in the control of vertigo." | 3.69 | When and how to use gentamicin in the treatment of Menière's disease. ( Bergenius, J; Möller, C; Odkvist, LM, 1997) |
"Five patients with Menière's disease and disabling vertigo were treated with two intratympanic instillations of gentamicin given at an interval of about 12 h." | 3.68 | Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy. ( Magnusson, M; Padoan, S, 1991) |
"For the medically refractory Meniere's disease patient, treatment options include intratympanic steroid injection, endolymphatic sac decompression, medical or surgical labyrinthectomy, and vestibular nerve section." | 3.01 | Recent surgical advances and continued controversies in medically refractory Meniere's disease. ( Hong, RS; Lucas, JC, 2023) |
"Diagnosis criteria of Meniere's disease are classified into Meniere's disease with typical cochlear and vestibular symptoms, and atypical Meniere's disease with either cochlear symptoms or vestibular symptoms." | 2.72 | Diagnostic and therapeutic strategies for Meniere's disease of the Japan Society for Equilibrium Research. ( Iwasaki, S; Kitahara, T; Murofushi, T; Origasa, H; Seo, T; Shojaku, H; Suzuki, M; Takeda, N; Watanabe, Y, 2021) |
"At two years post-treatment, the vertigo cure rate was 91." | 2.40 | [Chemical labyrinthectomy: results and applications]. ( Biboulet, R; Makeieff, M; Marlier, F; Mondain, M; Mouchet, F; Uziel, A, 1998) |
"Gentamicin has a well-known potential for damaging the peripheral vestibular organs." | 1.72 | Central nystagmus and alterations in vestibular tests due to an inadvertent gentamicin administration into spinal space: A CARE case report. ( Breinbauer, HA; Delano, PH; Eyzaguirre, M; Herrero, D, 2022) |
"Vertigo control, Meniere's Disease Functional Level Scale (MDFLS), Dizziness Handicap Inventory (DHI), and pure tone audiometry pre and posttreatment." | 1.56 | On-Demand and Low Dose Intratympanic Gentamicin for Meniere's Disease: A Customized Approach. ( Alarid-Coronel, JM; Burgos-Paez, A; Castro-Bórquez, KM; Celis-Aguilar, E; Escobar-Aispuro, L; León-Leyva, IC; López-Favela, LM; Martínez-Román, L; Obeso-Pereda, A; Trejo-González, CF; Verdiales-Lugo, S, 2020) |
"A high success rates of treating vertigo attacks with low concentration ITG in refractory unilateral MD patients is herein reported, while a significant difference was not observed in the hearing threshold compared with the healthy contralateral ear." | 1.48 | Low Concentration Intra-Tympanic Gentamicin Treatment for Menière's Disease: A Long-Term Follow Up. ( Ephraim, E; Gavriel, H; Lasry, R; Marom, T; Nathan, S, 2018) |
"However, moderate to flat sensorineural hearing loss was also observed." | 1.46 | Intralabyrinthine Vestibular Schwannoma Responsive to Intratympanic Gentamicin Treatment. ( Barbara, M; Covelli, E; Filippi, C; Marrone, V; Monini, S; Tarantini, S; Volpini, L, 2017) |
"Surgical removal of vestibular schwannoma causes acute vestibular symptoms, including postoperative vertigo and oscillopsia due to nystagmus." | 1.43 | Vertigo Perception and Quality of Life in Patients after Surgical Treatment of Vestibular Schwannoma with Pretreatment Prehabituation by Chemical Vestibular Ablation. ( Balatková, Z; Betka, J; Čada, Z; Čakrt, O; Černý, R; Chovanec, M; Fík, Z; Hrubá, S; Jeřábek, J; Kluh, J; Komarc, M; Profant, O; Zvěřina, E, 2016) |
"Nineteen patients with Meniere's disease were treated with intratympanic gentamicin injection." | 1.34 | [The effects of small dose of intratympanic gentamicin injection on intractable Meniere's disease]. ( Chi, F; Dai, C; Liu, J; Wang, Z; Zhang, G; Zhang, R, 2007) |
"Treatment of drop attacks is still a matter of discussion; most cases have a benign course with spontaneous remission and no treatment is necessary." | 1.33 | Drop attacks and vertical vertigo after transtympanic gentamicin: diagnosis and management. ( Bignami, M; Bruschini, L; Casani, AP; Dallan, I; Nacci, A, 2005) |
"Relief of vertigo was assessed by chart review and telephone interviews." | 1.33 | Long-term follow-up after gentamicin application via the Silverstein MicroWick in the treatment of Ménière's disease. ( Digges, EN; Hill, SL; Silverstein, H, 2006) |
"Vertigo was controlled in 95 per cent, whilst preserving hearing in 77 per cent." | 1.32 | Long-term results of gentamicin inner ear perfusion in Ménière's disease. ( Cook, JA; Suryanarayanan, R, 2004) |
"Gentamicin was applied by a high-precision insulin pump with a flow rate of 40 mg per day directly in front of the round window." | 1.31 | Continuous intratympanic infusion of gentamicin via a microcatheter in Menière's disease. ( Michel, O; Neugebauer, P; Schoendorf, J, 2001) |
"Of these, 68 patients had Meniere's disease; 4 patients had recurrent vertigo after endolymphatic sac surgery and were followed for at least 1 year." | 1.31 | Intratympanic gentamicin therapy for persistent vertigo after endolymphatic sac surgery. ( Leonetti, JP; Marzo, SJ, 2002) |
"Clinically significant sensorineural hearing loss occurred in 5 (20%) of 25 ears." | 1.30 | Intratympanic gentamicin treatment for Meniere's disease. ( Antonelli, PJ; McFeely, WJ; Rodriguez, FJ; Singleton, GT, 1998) |
"Two years after the treatment, rotatory vertigo was abolished in 81% of subjects, Tumarkin attacks were cured in 60%, and work capacity was severely reduced in 10% and moderately reduced in 17% of subjects." | 1.30 | Intratympanic gentamicin in Meniere's disease. ( Aalto, H; Ishizaki, H; Kaasinen, S; Pyykkö, I, 1998) |
"A future policy for surgical treatment of vertigo is discussed." | 1.29 | Surgical treatment of vertigo--the Karolinska Hospital policy. ( Ahlner, K; Bagger-Sjöbäck, D; Bergenius, J; Söderman, AC, 1996) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 14 (8.97) | 18.7374 |
1990's | 28 (17.95) | 18.2507 |
2000's | 56 (35.90) | 29.6817 |
2010's | 38 (24.36) | 24.3611 |
2020's | 20 (12.82) | 2.80 |
Authors | Studies |
---|---|
Breinbauer, HA | 1 |
Eyzaguirre, M | 1 |
Herrero, D | 1 |
Delano, PH | 1 |
de Amesti, F | 1 |
Santander, MJ | 1 |
Winter, M | 1 |
Li, S | 2 |
Pyykkö, I | 3 |
Zhang, Q | 2 |
Yang, J | 3 |
Duan, M | 2 |
Ilmari, P | 1 |
Spiegel, JL | 1 |
Stoycheva, I | 1 |
Weiss, BG | 1 |
Bertlich, M | 1 |
Rader, T | 1 |
Canis, M | 1 |
Ihler, F | 1 |
Webster, KE | 1 |
Galbraith, K | 1 |
Lee, A | 1 |
Harrington-Benton, NA | 1 |
Judd, O | 1 |
Kaski, D | 1 |
Maarsingh, OR | 1 |
MacKeith, S | 1 |
Ray, J | 1 |
Van Vugt, VA | 1 |
Burton, MJ | 1 |
Phillips, J | 1 |
Mikulec, AA | 1 |
Robinson, JM | 1 |
Skarinsky, D | 1 |
Anderson, JJ | 1 |
Lucas, JC | 1 |
Hong, RS | 1 |
Lee, JY | 1 |
Kim, MB | 1 |
Celis-Aguilar, E | 1 |
Castro-Bórquez, KM | 1 |
Obeso-Pereda, A | 1 |
Escobar-Aispuro, L | 1 |
Burgos-Paez, A | 1 |
Alarid-Coronel, JM | 1 |
Verdiales-Lugo, S | 1 |
León-Leyva, IC | 1 |
Trejo-González, CF | 1 |
López-Favela, LM | 1 |
Martínez-Román, L | 1 |
Quaranta, N | 2 |
Picciotti, P | 1 |
Molnár, A | 1 |
Maihoub, S | 1 |
Gáborján, A | 1 |
Tamás, L | 1 |
Szirmai, Á | 1 |
Basura, GJ | 1 |
Adams, ME | 1 |
Monfared, A | 1 |
Schwartz, SR | 1 |
Antonelli, PJ | 2 |
Burkard, R | 1 |
Bush, ML | 1 |
Bykowski, J | 1 |
Colandrea, M | 1 |
Derebery, J | 1 |
Kelly, EA | 1 |
Kerber, KA | 1 |
Koopman, CF | 1 |
Kuch, AA | 1 |
Marcolini, E | 1 |
McKinnon, BJ | 1 |
Ruckenstein, MJ | 1 |
Valenzuela, CV | 1 |
Vosooney, A | 1 |
Walsh, SA | 1 |
Nnacheta, LC | 1 |
Dhepyasuwan, N | 1 |
Buchanan, EM | 1 |
Scarpa, A | 1 |
Cassandro, C | 1 |
De Luca, P | 1 |
Viola, P | 1 |
Greco, A | 1 |
de Vincentiis, M | 1 |
Cassandro, E | 1 |
Ralli, M | 1 |
Espinosa-Sanchez, JM | 1 |
Lopez-Escamez, JA | 1 |
Jiang, M | 1 |
Zhang, Z | 1 |
Zhao, C | 1 |
Iwasaki, S | 2 |
Shojaku, H | 1 |
Murofushi, T | 3 |
Seo, T | 1 |
Kitahara, T | 2 |
Origasa, H | 1 |
Watanabe, Y | 1 |
Suzuki, M | 1 |
Takeda, N | 1 |
Gill, C | 1 |
Muzaffar, J | 1 |
Kumar, R | 1 |
Irving, R | 1 |
Zhang, D | 1 |
Lv, Y | 1 |
Li, X | 1 |
Li, Y | 2 |
Song, Y | 1 |
Fan, Z | 1 |
Wang, H | 1 |
Wu, Y | 1 |
Zhou, Y | 1 |
Yu, J | 1 |
Song, Z | 1 |
Dai, C | 2 |
Wang, J | 2 |
Liu, YF | 1 |
Renk, E | 1 |
Rauch, SD | 1 |
Xu, HX | 1 |
Pullen, RL | 1 |
Covelli, E | 1 |
Volpini, L | 1 |
Filippi, C | 1 |
Tarantini, S | 1 |
Marrone, V | 1 |
Monini, S | 1 |
Barbara, M | 1 |
Lee, MY | 1 |
Hyun, JH | 1 |
Suh, MW | 1 |
Ahn, JC | 1 |
Chung, PS | 1 |
Jung, JY | 1 |
Rhee, CK | 1 |
Wang, XY | 1 |
Büki, B | 4 |
Jünger, H | 4 |
Lundberg, YW | 1 |
Nathan, S | 1 |
Lasry, R | 1 |
Ephraim, E | 1 |
Marom, T | 1 |
Gavriel, H | 1 |
Jia, H | 1 |
Li, G | 1 |
Huang, M | 1 |
Zhu, W | 1 |
Wang, Z | 2 |
Wu, H | 1 |
Reynard, P | 1 |
Karkas, A | 1 |
Gavid, M | 1 |
Lelonge, Y | 1 |
Bertholon, P | 1 |
Reichmayr, C | 1 |
Sterrer, E | 1 |
Bachtiar, A | 1 |
Layr, M | 1 |
Loader, B | 1 |
Zhai, F | 3 |
Shi, F | 1 |
Dai, CF | 3 |
Fan, C | 1 |
Nicolas, S | 1 |
Kmeid, M | 1 |
Mansour, C | 1 |
Fraysse, B | 1 |
Deguine, O | 1 |
Marx, M | 1 |
Fraysse, ME | 1 |
Hertz, J | 1 |
Djurhuus, BD | 1 |
Harcourt, JP | 2 |
Lambert, A | 1 |
Wong, PY | 1 |
Patel, M | 2 |
Agarwal, K | 2 |
Golding, JF | 2 |
Bronstein, AM | 2 |
Huang, CJ | 1 |
Wan, TK | 1 |
Fang, TY | 1 |
Wang, PC | 1 |
Ward, B | 1 |
Wettstein, V | 1 |
Golding, J | 1 |
Corallo, G | 1 |
Nuti, D | 1 |
Trabalzini, F | 1 |
Mandala, M | 1 |
Quaglieri, S | 1 |
Gatti, O | 1 |
Rebecchi, E | 1 |
Manfrin, M | 2 |
Tinelli, C | 1 |
Mira, E | 2 |
Benazzo, M | 1 |
Kumar, E | 1 |
Sharma, H | 1 |
Giannuzzi, AL | 2 |
Zhang, R | 2 |
Zhang, T | 1 |
Steyger, PS | 2 |
Olusesi, AD | 1 |
Hassan, SB | 1 |
Oyeyipo, Y | 1 |
Ukwuije, UC | 1 |
Oyeniran, O | 1 |
van Kerckhoven, G | 1 |
Mert, A | 1 |
De Ru, JA | 1 |
Rah, YC | 1 |
Han, JJ | 1 |
Park, J | 1 |
Choi, BY | 1 |
Koo, JW | 1 |
Liu, B | 3 |
Zhang, S | 1 |
Leng, Y | 2 |
Zhou, R | 2 |
Liu, J | 3 |
Kong, W | 1 |
Leng, YM | 1 |
Shi, H | 1 |
Zhou, RH | 1 |
Liu, JJ | 1 |
Zhang, WJ | 1 |
Zhang, SL | 2 |
Kong, WJ | 2 |
Sam, G | 1 |
Chung, DW | 1 |
van der Hoeven, R | 1 |
Verweij, S | 1 |
Becker, M | 1 |
Arshad, Q | 1 |
Hariri, M | 1 |
Rea, P | 1 |
Seemungal, BM | 1 |
Liu, D | 1 |
Čada, Z | 1 |
Balatková, Z | 1 |
Chovanec, M | 1 |
Čakrt, O | 1 |
Hrubá, S | 1 |
Jeřábek, J | 1 |
Zvěřina, E | 1 |
Profant, O | 1 |
Fík, Z | 1 |
Komarc, M | 1 |
Betka, J | 1 |
Kluh, J | 1 |
Černý, R | 1 |
Suryanarayanan, R | 2 |
Srinivasan, VR | 1 |
O'Sullivan, G | 1 |
Postema, RJ | 1 |
Kingma, CM | 1 |
Wit, HP | 1 |
Albers, FW | 1 |
Van Der Laan, BF | 1 |
Steenerson, RL | 1 |
Hardin, RB | 1 |
Cronin, GW | 1 |
Kyrodimos, E | 1 |
Aidonis, I | 1 |
Sismanis, A | 1 |
Lee, L | 1 |
Pensak, ML | 1 |
De Valck, CF | 1 |
Van Rompaey, V | 1 |
Wuyts, EL | 1 |
Van de Heyning, PH | 1 |
Hsieh, LC | 1 |
Lin, HC | 1 |
Tsai, HT | 1 |
Ko, YC | 1 |
Shu, MT | 1 |
Lin, LH | 1 |
Nguyen, KD | 1 |
Minor, LB | 6 |
Della Santina, CC | 3 |
Carey, JP | 4 |
Silverstein, H | 2 |
Wazen, J | 1 |
Van Ess, MJ | 1 |
Daugherty, J | 1 |
Alameda, YA | 1 |
Liu, JP | 1 |
Wang, Q | 1 |
Derebery, MJ | 1 |
Fisher, LM | 1 |
Berliner, K | 1 |
Chung, J | 1 |
Green, K | 1 |
Platz, M | 1 |
Haslwanter, T | 4 |
Avan, P | 2 |
Katzenell, U | 1 |
Gordon, M | 1 |
Page, M | 1 |
Pullens, B | 1 |
van Benthem, PP | 1 |
Merkus, P | 1 |
Falcioni, M | 1 |
Perez, N | 1 |
Martin, E | 1 |
Zubieta, JL | 1 |
Romero, MD | 1 |
Garcia-Tapia, R | 1 |
Abou-Halawa, AS | 1 |
Poe, DS | 2 |
Marín Garrido, C | 1 |
Fraile Rodrigo, J | 1 |
Naya Gálvez, MJ | 1 |
Samperiz, LC | 1 |
Hernández Montero, E | 1 |
Ortiz García, A | 1 |
Peng, GC | 2 |
Cremer, PD | 2 |
Assimakopoulos, D | 1 |
Patrikakos, G | 1 |
Wu, IC | 1 |
Marzo, SJ | 2 |
Gilony, D | 1 |
Wolf, M | 1 |
Kronenberg, J | 1 |
Hillman, TA | 1 |
Chen, DA | 1 |
Arriaga, MA | 1 |
Diamond, C | 1 |
O'Connell, DA | 1 |
Hornig, JD | 1 |
Liu, R | 1 |
Okuda, T | 1 |
Sugahara, K | 1 |
Shimogori, H | 1 |
Yamashita, H | 1 |
Huang, W | 1 |
Xu, H | 1 |
Gao, B | 1 |
Chia, SH | 1 |
Gamst, AC | 1 |
Anderson, JP | 1 |
Harris, JP | 1 |
Cook, JA | 1 |
Carey, J | 1 |
Longridge, NS | 1 |
Bertino, G | 1 |
Durso, D | 1 |
Casati, L | 1 |
Pierchała, K | 1 |
Krzeska-Malinowska, I | 1 |
Kowalska, M | 1 |
Bartoszewicz, R | 1 |
Niemczyk, K | 1 |
Picciotti, PM | 1 |
Fiorita, A | 1 |
Di Nardo, W | 1 |
Paludetti, G | 1 |
Maurizi, M | 1 |
Lin, FR | 1 |
Migliaccio, AA | 1 |
Gouveris, H | 1 |
Lange, G | 3 |
Mann, WJ | 1 |
Helling, K | 1 |
Scherer, H | 1 |
Flanagan, S | 1 |
Mukherjee, P | 1 |
Tonkin, J | 1 |
Ghossaini, SN | 1 |
Wazen, JJ | 1 |
Dallan, I | 1 |
Bruschini, L | 1 |
Nacci, A | 1 |
Bignami, M | 1 |
Casani, AP | 1 |
Horii, A | 1 |
Saika, T | 1 |
Uno, A | 1 |
Nishiike, S | 1 |
Mitani, K | 1 |
Nishimura, M | 1 |
Fukushima, M | 1 |
Nakagawa, A | 1 |
Masumura, C | 1 |
Sasaki, T | 1 |
Kizawa, K | 1 |
Kubo, T | 1 |
Smith, WK | 1 |
Sandooram, D | 1 |
Prinsley, PR | 1 |
Takai, Y | 1 |
Ushio, M | 1 |
Ishiyama, G | 2 |
Ishiyama, A | 2 |
Kerber, K | 1 |
Baloh, RW | 2 |
Hill, SL | 1 |
Digges, EN | 1 |
Akkuzu, B | 1 |
Ozgirgin, N | 1 |
Ozlüoğlu, LN | 1 |
Lopez, I | 1 |
Kasemsuwan, L | 1 |
Jariengprasert, C | 1 |
Ruencharopen, S | 1 |
Orathai, P | 1 |
Zhang, G | 1 |
Chi, F | 1 |
Magnusson, M | 4 |
Kahlon, B | 1 |
Karlberg, M | 3 |
Lindberg, S | 1 |
Siesjö, P | 1 |
Bodmer, D | 1 |
Morong, S | 1 |
Stewart, C | 1 |
Alexander, A | 1 |
Chen, JM | 1 |
Nedzelski, JM | 4 |
Katzke, D | 1 |
Hellström, S | 1 |
Odkvist, L | 1 |
Chiong, CM | 1 |
Fradet, G | 1 |
Schessel, DA | 2 |
Bryce, GE | 3 |
Pfleiderer, AG | 3 |
Söderman, AC | 2 |
Ahlner, K | 1 |
Bagger-Sjöbäck, D | 2 |
Bergenius, J | 4 |
Hirsch, BE | 1 |
Kamerer, DB | 1 |
Halmagyi, GM | 2 |
Yavor, RA | 1 |
Driscoll, CL | 2 |
Kasperbauer, JL | 1 |
Facer, GW | 2 |
Harner, SG | 2 |
Beatty, CW | 2 |
Odkvist, LM | 1 |
Möller, C | 1 |
Wong, DL | 1 |
Rutka, JA | 2 |
Blakley, BW | 1 |
Sala, T | 1 |
Corsten, M | 1 |
Marsan, J | 1 |
Schramm, D | 1 |
Robichaud, J | 1 |
McFeely, WJ | 1 |
Singleton, GT | 1 |
Rodriguez, FJ | 1 |
Kaasinen, S | 1 |
Ishizaki, H | 2 |
Aalto, H | 2 |
Youssef, TF | 1 |
Waterston, JA | 1 |
Tribukait, A | 1 |
Brantberg, K | 1 |
Mondain, M | 1 |
Mouchet, F | 1 |
Marlier, F | 1 |
Makeieff, M | 1 |
Biboulet, R | 1 |
Uziel, A | 1 |
Eklund, S | 1 |
Atlas, JT | 1 |
Parnes, LS | 1 |
Bath, AP | 1 |
Walsh, RM | 1 |
Bance, ML | 1 |
Quaranta, A | 1 |
Aloisi, A | 1 |
De Benedittis, G | 1 |
Scaringi, A | 1 |
Charabi, S | 1 |
Thomsen, J | 1 |
Tos, M | 1 |
Schoendorf, J | 1 |
Neugebauer, P | 1 |
Michel, O | 1 |
Walsted, A | 1 |
McDonald, TJ | 1 |
Tjell, C | 1 |
Langius, A | 1 |
Akagi, H | 1 |
Yuen, K | 1 |
Maeda, Y | 1 |
Fukushima, K | 1 |
Kariya, S | 1 |
Orita, Y | 1 |
Kataoka, Y | 1 |
Ogawa, T | 1 |
Nishizaki, K | 1 |
Hoffer, ME | 1 |
Kopke, RD | 1 |
Weisskopf, P | 1 |
Gottshall, K | 1 |
Allen, K | 1 |
Wester, D | 1 |
Leonetti, JP | 1 |
Iwashima, Y | 1 |
Misawa, H | 1 |
Katayama, N | 1 |
Mori, S | 1 |
Nakashima, T | 1 |
Inoue, H | 1 |
Uchi, Y | 1 |
Nogami, K | 1 |
Uemura, T | 1 |
Seidman, M | 1 |
Hirvonen, T | 1 |
See, GB | 1 |
Mahmud, MR | 1 |
Zurin, AA | 1 |
Putra, SH | 1 |
Saim, LB | 1 |
Padoan, S | 3 |
Johansson, R | 2 |
Tamai, IY | 1 |
Sayers, JF | 1 |
Mooradian, AD | 1 |
Leliever, WC | 1 |
Debain, JJ | 1 |
Freyss, G | 1 |
Poulain, H | 1 |
Paparella, MM | 1 |
VanOmmen, RA | 1 |
Banck, G | 3 |
Belfrage, S | 3 |
Juhlin, I | 3 |
Nordström, L | 3 |
Tjernström, O | 3 |
Toremalm, NG | 3 |
Roydhouse, N | 1 |
Ewald, U | 1 |
Jernelius, H | 1 |
Meyers, RM | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Effectiveness of Transtympanic Steroids in Unilateral Ménière's Disease: a Randomised Controlled Double-Blind Trial[NCT00802529] | Phase 2/Phase 3 | 60 participants (Actual) | Interventional | 2009-04-30 | Completed | ||
Vertigo Perception and Quality of Life in Patients After Surgical Treatment of Vestibular Schwannoma With Pretreatment Prehabituation by Chemical Vestibular Ablation[NCT02963896] | 20 participants (Actual) | Interventional | 2014-01-31 | Completed | |||
Assessment of Visual Sensitivity, Psychiatric Profile and Quality of Life Following Vestibular Schwannoma Surgery in Patients Prehabituated by Chemical Vestibular Ablation[NCT03638310] | 37 participants (Actual) | Interventional | 2016-01-01 | Completed | |||
Is 3D Optokinetic Stimulation in Virtual Reality Space an Efficient Tool for Improvement of Central Compensation in Patients After Vestibular Schwannoma Surgery?[NCT05578560] | 60 participants (Anticipated) | Interventional | 2020-01-01 | Recruiting | |||
Gentamicin Treatment Prior to Vestibular Schwannoma Surgery in Patients With Definite Remaining Vestibular Function[NCT02379754] | Phase 4 | 0 participants (Actual) | Interventional | 2015-01-31 | Withdrawn | ||
Gentamicin Treatment Prior to Vestibular Schwannoma Surgery in Patients With no Measurable Remaining Vestibular Function[NCT02415257] | Phase 4 | 0 participants (Actual) | Interventional | 2015-04-30 | Withdrawn | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Hearing was measured as ipsilesional pure-tone threshold at Baseline, 1month, 2months, 6months, 12month, 18months and 24 months follow-up. Hearing level was taken as the average threshold across 0.5, 1, 2 and 3KHz. (NCT00802529)
Timeframe: Baseline, 1,2,6,12,18 and 24months after initial treatment
Intervention | dB (Mean) | ||||||
---|---|---|---|---|---|---|---|
Baseline | 1month | 2months | 6months | 12months | 18months | 24months | |
Gentamicin | 51.5 | 52.18 | 48.99 | 45.48 | 47.34 | 44.82 | 49.1 |
Steroid (Methylprednisolone) | 53.25 | 49.29 | 49.83 | 46.67 | 47.02 | 48.44 | 46.9 |
"Speech discrimination was measured at Baseline, 1month, 2months, 6months, 12month and 24 months follow-up.~Speech discrimination was assessed by means of ipsilesional suprathreshold word recognition (%). Arthur Boothroyd's isophonemic word lists (AB wordlists, Guymark, Southampton) comprising sets of 10 words were played to the ipsilesional ear at the low-frequency pure-tone threshold of 0·5, 1 and 2 kHz +30dB with masking sound in the contralesional ear if necessary. The formula for masking level was: low-frequency pure-tone threshold in ipsilesional ear - bone conduction mean threshold (0·5, 1 and 2KHz) in contralesional ear - 40dB. Speech loudness and masking were rounded to the nearest 5dB. Step increments and decrements of 10dB for speech loudness and masking were used to attain the maximum speech discrimination score." (NCT00802529)
Timeframe: Baseline, 1,2,6,12 and 24months after initial treatment
Intervention | Percentage correct (Mean) | |||||
---|---|---|---|---|---|---|
Baseline | 1month | 2months | 6months | 12months | 24months | |
Gentamicin | 72.10 | 69.43 | 74.31 | 76.35 | 71.58 | 64.99 |
Steroid (Methylprednisolone) | 64.97 | 71.78 | 76.10 | 75.63 | 73.43 | 76.32 |
The number of vertigo attacks between 18-24months follow-up were taken retrospectively during a face-to-face appointment at 24 months follow-up and compared to 6 month pre-enrollment baseline (as per Committee on Hearing and Equilibrium guidelines). (NCT00802529)
Timeframe: 6month pre-enrollment baseline, 18-24 months after initial treatment
Intervention | Vertigo Attacks (Mean) | |
---|---|---|
Baseline | 18-24months | |
Gentamicin | 19.93 | 2.5 |
Steroid (Methylprednisolone) | 16.4 | 1.6 |
18 reviews available for gentamicin and Vertigo
Article | Year |
---|---|
Intratympanic gentamicin compared with placebo for Ménière's disease.
Topics: Gentamicins; Humans; Meniere Disease; Systematic Reviews as Topic; Tinnitus; Vertigo | 2022 |
Consensus on intratympanic drug delivery for Menière's disease.
Topics: Anti-Bacterial Agents; Consensus; Gentamicins; Humans; Injection, Intratympanic; Meniere Disease; Tr | 2022 |
Intratympanic gentamicin for Ménière's disease.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Gentamicins; Humans; Meniere Disease; Tinnitus; Verti | 2023 |
Recent surgical advances and continued controversies in medically refractory Meniere's disease.
Topics: Deafness; Ear, Inner; Gentamicins; Hearing Loss; Humans; Meniere Disease; Vertigo | 2023 |
The pharmacological management of vertigo in Meniere disease.
Topics: Adrenal Cortex Hormones; Betahistine; Clinical Trials as Topic; Diuretics; Female; Gentamicins; Huma | 2020 |
What is the efficacy of gentamicin on the incidence of vertigo attacks and hearing in patients with Meniere's disease compared with steroids? A meta-analysis.
Topics: Anti-Bacterial Agents; Gentamicins; Hearing; Humans; Incidence; Meniere Disease; Steroids; Treatment | 2021 |
Diagnostic and therapeutic strategies for Meniere's disease of the Japan Society for Equilibrium Research.
Topics: Anti-Bacterial Agents; Audiometry; Endolymphatic Hydrops; Endolymphatic Sac; Gentamicins; Healthy Li | 2021 |
Intratympanic gentamicin for Ménière's disease or syndrome.
Topics: Anti-Bacterial Agents; Ear, Middle; Gentamicins; Humans; Meniere Disease; Randomized Controlled Tria | 2011 |
Treatment of Ménière's disease by intratympanic gentamicin application.
Topics: Absorption; Administration, Topical; Anti-Bacterial Agents; Gentamicins; Humans; Meniere Disease; Tr | 2003 |
Intratympanic therapies for sensorineural hearing loss and vertigo.
Topics: Anti-Bacterial Agents; Catheterization; Diagnosis, Differential; Gentamicins; Hearing Loss, Sensorin | 2003 |
Systematic review of intratympanic gentamicin in Meniere's disease.
Topics: Administration, Topical; Anti-Bacterial Agents; Ear, Inner; Gentamicins; Hearing; Humans; Meniere Di | 2003 |
Intratympanic gentamicin therapy for Ménière's disease: a meta-analysis.
Topics: Anti-Bacterial Agents; Catheter Ablation; Gentamicins; Hearing Loss; Humans; Meniere Disease; Treatm | 2004 |
Intratympanic gentamicin for the treatment of Meniere's disease and other forms of peripheral vertigo.
Topics: Administration, Topical; Anti-Bacterial Agents; Gentamicins; Humans; Meniere Disease; Round Window, | 2004 |
Meta-analysis of intratympanic gentamicin.
Topics: Anti-Bacterial Agents; Gentamicins; Humans; Meniere Disease; Tympanic Membrane; Vertigo | 2005 |
An update on the surgical treatment of Ménière's diseases.
Topics: Anti-Bacterial Agents; Ear, Inner; Endolymphatic Sac; Gentamicins; Hearing Loss; Humans; Meniere Dis | 2006 |
Intratympanic gentamicin instillation as treatment of unilateral Menière's disease: update of an ongoing study.
Topics: Adult; Aged; Audiometry, Pure-Tone; Female; Gentamicins; Hearing; Humans; Male; Meniere Disease; Tym | 1993 |
Clinical forum: a review of intratympanic therapy.
Topics: Anti-Bacterial Agents; Gentamicins; Hearing Disorders; Humans; Meniere Disease; Streptomycin; Termin | 1997 |
[Chemical labyrinthectomy: results and applications].
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ear, Inner; Female; Gentamicins; Humans; Male | 1998 |
10 trials available for gentamicin and Vertigo
Article | Year |
---|---|
Efficacy of Intratympanic OTO-104 for the Treatment of Ménière's Disease: The Outcome of Three Randomized, Double-Blind, Placebo-Controlled Studies.
Topics: Double-Blind Method; Gentamicins; Humans; Injection, Intratympanic; Injections; Meniere Disease; Tre | 2023 |
Author's reply to the Letter to the Editor "Therapeutic strategies in the treatment of Menière's disease: the Italian experience".
Topics: Anti-Bacterial Agents; Gentamicins; Humans; Italy; Meniere Disease; Treatment Outcome; Vertigo | 2020 |
The effect of intratympanic gentamicin for treatment of Ménière's disease on lower frequency hearing.
Topics: Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Female; Gentamicins; Hearing; Humans; Injection, | 2016 |
Intratympanic methylprednisolone versus gentamicin in patients with unilateral Ménière's disease: a randomised, double-blind, comparative effectiveness trial.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Double-Blind Method; Female; Gentamicins; Hearing L | 2016 |
Intratympanic gentamicin therapy for control of vertigo in unilateral Menire's disease: a prospective, double-blind, randomized, placebo-controlled trial.
Topics: Anti-Bacterial Agents; Double-Blind Method; Drug Administration Schedule; Ear, Middle; Female; Follo | 2008 |
Recovery of subjective visual horizontal after unilateral vestibular deafferentation by intratympanic instillation of gentamicin.
Topics: Adult; Aged; Caloric Tests; Drug Administration Routes; Ear, Middle; Electronystagmography; Female; | 2006 |
[Intratympanic treatment in Meniere's disease: the effect of gentamicin and dexamethasone on vertigo control and hearing].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Dexamethasone; Drug Therapy, Combination; Female; G | 2006 |
Preoperative vestibular ablation with gentamicin and vestibular 'prehab' enhance postoperative recovery after surgery for pontine angle tumours--first report.
Topics: Adult; Aged; Female; Gentamicins; Humans; Male; Middle Aged; Neuroma, Acoustic; Otorhinolaryngologic | 2007 |
Preoperative vestibular ablation with gentamicin and vestibular 'prehab' enhance postoperative recovery after surgery for pontine angle tumours--first report.
Topics: Adult; Aged; Female; Gentamicins; Humans; Male; Middle Aged; Neuroma, Acoustic; Otorhinolaryngologic | 2007 |
Preoperative vestibular ablation with gentamicin and vestibular 'prehab' enhance postoperative recovery after surgery for pontine angle tumours--first report.
Topics: Adult; Aged; Female; Gentamicins; Humans; Male; Middle Aged; Neuroma, Acoustic; Otorhinolaryngologic | 2007 |
Preoperative vestibular ablation with gentamicin and vestibular 'prehab' enhance postoperative recovery after surgery for pontine angle tumours--first report.
Topics: Adult; Aged; Female; Gentamicins; Humans; Male; Middle Aged; Neuroma, Acoustic; Otorhinolaryngologic | 2007 |
Intratympanic gentamicin for control of vertigo in Meniere's disease: vestibular signs that specify completion of therapy.
Topics: Adult; Aged; Caloric Tests; Clinical Protocols; Ear, Inner; Female; Gentamicins; Hearing Disorders; | 1999 |
Treatment of Menière's disease with topical gentamicin: a preliminary report.
Topics: Administration, Topical; Caloric Tests; Catheterization; Contraindications; Ear, Middle; Follow-Up S | 1992 |
128 other studies available for gentamicin and Vertigo
Article | Year |
---|---|
Central nystagmus and alterations in vestibular tests due to an inadvertent gentamicin administration into spinal space: A CARE case report.
Topics: Bilateral Vestibulopathy; Gentamicins; Humans; Male; Middle Aged; Nystagmus, Pathologic; Vertigo; Ve | 2022 |
[Consensus on intratympanic drug delivery for Menière's disease].
Topics: Anti-Bacterial Agents; Consensus; Gentamicins; Humans; Meniere Disease; Vertigo | 2022 |
Vestibular and audiometric results after endolymphatic mastoid shunt surgery in patients with Menière's disease.
Topics: Endolymphatic Shunt; Gentamicins; Humans; Mastoid; Meniere Disease; Retrospective Studies; Vertigo; | 2023 |
Change of VOR gain and pure-tone threshold after single low-dose intratympanic gentamicin injection in Meniere's disease.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry, Pure-Tone; Auditory Threshold; Ge | 2020 |
On-Demand and Low Dose Intratympanic Gentamicin for Meniere's Disease: A Customized Approach.
Topics: Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Female; Gentamicins; Humans; Male; Meniere Disea | 2020 |
Intratympanic gentamycine for Ménière's disease: is there a selective vestibulotoxic effect?
Topics: Anti-Bacterial Agents; Audiometry, Pure-Tone; Gentamicins; Hearing Loss; Humans; Meniere Disease; Tr | 2020 |
Clinical Practice Guideline: Ménière's Disease.
Topics: Audiometry; Counseling; Diagnosis, Differential; Diuretics; Ear, Inner; Gentamicins; Glucocorticoids | 2020 |
Letter to the Editor: Intratympanic gentamicin for Ménière's disease: is there a selective vestibulotoxic effect?
Topics: Audiometry, Pure-Tone; Gentamicins; Humans; Meniere Disease; Vertigo | 2020 |
Triple Canal Occlusion for the Treatment of Intractable Menière's Disease.
Topics: Endolymphatic Sac; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Aged; Otologic Surgica | 2021 |
Long-term efficacy of triple semicircular canal plugging in the treatment of patients with ipsilateral delayed endolymphatic hydrops.
Topics: Anti-Bacterial Agents; Audiometry, Pure-Tone; Complementary Therapies; Endolymphatic Hydrops; Female | 2021 |
Intratympanic gentamicin injection for refractory ménière's disease (MD) has potential effect in preventing contralateral MD occurrence.
Topics: Adult; Aged; Caloric Tests; Female; Gentamicins; Hearing Loss; Humans; Injection, Intratympanic; Mal | 2021 |
Efficacy of Intratympanic Gentamicin in Menière's Disease With and Without Migraine.
Topics: Adult; Aged; Anti-Bacterial Agents; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Aged; | 2017 |
Navigating the challenges of Meniere disease.
Topics: Gentamicins; Humans; Injection, Intratympanic; Male; Meniere Disease; Middle Aged; Nursing Assessmen | 2017 |
Intralabyrinthine Vestibular Schwannoma Responsive to Intratympanic Gentamicin Treatment.
Topics: Adult; Anti-Bacterial Agents; Female; Gentamicins; Hearing Loss, Sensorineural; Humans; Neuroma, Aco | 2017 |
Treatment of peripheral vestibular dysfunction using photobiomodulation.
Topics: Animals; Anti-Bacterial Agents; Cochlea; Ear, Inner; Gentamicins; Low-Level Light Therapy; Male; Rat | 2017 |
[Small doses of gentamicin drum indoor injection treatment of intractableMénière disease clinical observation of the impact of the hearing].
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Audiometry, Speech; Female; Gentamicins; | 2016 |
Vitamin D supplementation may improve symptoms in Meniere's disease.
Topics: Anti-Bacterial Agents; Autoimmunity; Cytokines; Dietary Supplements; Gentamicins; Humans; Inflammati | 2018 |
Low Concentration Intra-Tympanic Gentamicin Treatment for Menière's Disease: A Long-Term Follow Up.
Topics: Anti-Bacterial Agents; Cohort Studies; Female; Follow-Up Studies; Gentamicins; Humans; Injections; M | 2018 |
Intratympanic Gentamicin for Small Vestibular Schwannomas With Intractable Vertigo.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Caloric Tests; Female; Gentamicins; Humans; Injectio | 2018 |
Delayed endolymphatic hydrops. Special emphasis on nystagmus associated with episodes and contribution of chemical labyrinthectomy.
Topics: Adult; Aged; Anti-Bacterial Agents; Caloric Tests; Deafness; Endolymphatic Hydrops; Female; Gentamic | 2018 |
Tenotomy of the middle ear muscles : An unknown surgical approach in Meniere's disease.
Topics: Adult; Ear, Middle; Female; Gentamicins; Humans; Meniere Disease; Tenotomy; Treatment Outcome; Verti | 2019 |
Preliminary study on the mechanism underlying the interaction of balance dysfunction and anxiety disorder.
Topics: Animals; Anti-Bacterial Agents; Anxiety Disorders; Biogenic Amines; Gentamicins; Locus Coeruleus; Po | 2019 |
Long-term Vertigo Control and Vestibular Function After Low-dose On-demand Transtympanic Gentamicin for Refractory Menière's Disease.
Topics: Adult; Anti-Bacterial Agents; Caloric Tests; Female; Gentamicins; Humans; Injection, Intratympanic; | 2019 |
[Bilateral vestibulopathy after intravenous gentamicin therapy].
Topics: Aged; Bilateral Vestibulopathy; Gentamicins; Head Impulse Test; Humans; Male; Reflex, Vestibulo-Ocul | 2019 |
Long-Term Follow-Up of Intratympanic Methylprednisolone Versus Gentamicin in Patients With Unilateral Menière's Disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Ear, Inner; Female; Follow-Up Studies; Gentamicins; Humans; Inje | 2019 |
CASP9 genotype confers gentamicin susceptibility in intratympanic treatment of intractable vertigo caused by Ménière's disease.
Topics: Adult; Aged; Aged, 80 and over; Caspase 9; Female; Follow-Up Studies; Gentamicins; Humans; Injection | 2019 |
Patient Perceptions of Effectiveness in Treatments for Menière's Disease: a National Survey in Italy.
Topics: Absenteeism; Anti-Bacterial Agents; Betahistine; Cross-Sectional Studies; Diet Therapy; Diuretics; F | 2019 |
Intratympanic gentamicin treatment 'as needed' for Meniere's disease. Long-term analysis using the Kaplan-Meier method.
Topics: Adult; Aged; Anti-Bacterial Agents; Drug Administration Schedule; Female; Gentamicins; Humans; Kapla | 2014 |
The disabling vertigo in vestibular schwannoma: is labyrinthine or retrolabyrinthine?
Topics: Anti-Bacterial Agents; Female; Gentamicins; Humans; Neuroma, Acoustic; Tympanic Membrane; Vertigo | 2013 |
The disabling vertigo in vestibular schwannoma: is labyrinthine or retro-labyrinthine?
Topics: Anti-Bacterial Agents; Female; Gentamicins; Humans; Neuroma, Acoustic; Tympanic Membrane; Vertigo | 2013 |
Preclinical and clinical studies of unrelieved aural fullness following intratympanic gentamicin injection in patients with intractable Ménière's disease.
Topics: Adult; Animals; Anti-Bacterial Agents; Female; Gentamicins; Guinea Pigs; Humans; Male; Meniere Disea | 2013 |
Chemical labyrinthectomy for the worse ear of adult Nigerians with bilateral Meniere's disease: preliminary report of treatment outcomes.
Topics: Anti-Bacterial Agents; Audiometry, Pure-Tone; Ear, Inner; Female; Gentamicins; Humans; Injection, In | 2015 |
Treatment of vertigo and postural instability using visual illusions.
Topics: Aged; Dizziness; Gentamicins; Humans; Illusions; Male; Postural Balance; Treatment Outcome; Vertigo; | 2014 |
Management of intractable Ménière's disease after intratympanic injection of gentamicin.
Topics: Adult; Aged; Cohort Studies; Endolymphatic Hydrops; Female; Follow-Up Studies; Gentamicins; Hearing | 2015 |
Intratympanic injection in delayed endolymphatic hydrops.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Audiometry; Dexamethasone; Dose-Response Relationship, Dru | 2015 |
Modified titration intratympanic gentamicin injection for unilateral intractable Ménière's disease.
Topics: Adult; Drug Administration Schedule; Ear, Inner; Female; Follow-Up Studies; Gentamicins; Hearing; Hu | 2015 |
Intratympanic steroids injection is effective for the treatment of drop attacks with Ménière's disease and delayed endolymphatic hydrops: A retrospective study.
Topics: Adult; Anti-Bacterial Agents; Dexamethasone; Drug Therapy, Combination; Endolymphatic Hydrops; Femal | 2016 |
Vertigo Perception and Quality of Life in Patients after Surgical Treatment of Vestibular Schwannoma with Pretreatment Prehabituation by Chemical Vestibular Ablation.
Topics: Adult; Aged; Caloric Tests; Female; Gentamicins; Humans; Male; Middle Aged; Neuroma, Acoustic; Posto | 2016 |
Vertigo Perception and Quality of Life in Patients after Surgical Treatment of Vestibular Schwannoma with Pretreatment Prehabituation by Chemical Vestibular Ablation.
Topics: Adult; Aged; Caloric Tests; Female; Gentamicins; Humans; Male; Middle Aged; Neuroma, Acoustic; Posto | 2016 |
Vertigo Perception and Quality of Life in Patients after Surgical Treatment of Vestibular Schwannoma with Pretreatment Prehabituation by Chemical Vestibular Ablation.
Topics: Adult; Aged; Caloric Tests; Female; Gentamicins; Humans; Male; Middle Aged; Neuroma, Acoustic; Posto | 2016 |
Vertigo Perception and Quality of Life in Patients after Surgical Treatment of Vestibular Schwannoma with Pretreatment Prehabituation by Chemical Vestibular Ablation.
Topics: Adult; Aged; Caloric Tests; Female; Gentamicins; Humans; Male; Middle Aged; Neuroma, Acoustic; Posto | 2016 |
Vertigo Perception and Quality of Life in Patients after Surgical Treatment of Vestibular Schwannoma with Pretreatment Prehabituation by Chemical Vestibular Ablation.
Topics: Adult; Aged; Caloric Tests; Female; Gentamicins; Humans; Male; Middle Aged; Neuroma, Acoustic; Posto | 2016 |
Vertigo Perception and Quality of Life in Patients after Surgical Treatment of Vestibular Schwannoma with Pretreatment Prehabituation by Chemical Vestibular Ablation.
Topics: Adult; Aged; Caloric Tests; Female; Gentamicins; Humans; Male; Middle Aged; Neuroma, Acoustic; Posto | 2016 |
Vertigo Perception and Quality of Life in Patients after Surgical Treatment of Vestibular Schwannoma with Pretreatment Prehabituation by Chemical Vestibular Ablation.
Topics: Adult; Aged; Caloric Tests; Female; Gentamicins; Humans; Male; Middle Aged; Neuroma, Acoustic; Posto | 2016 |
Vertigo Perception and Quality of Life in Patients after Surgical Treatment of Vestibular Schwannoma with Pretreatment Prehabituation by Chemical Vestibular Ablation.
Topics: Adult; Aged; Caloric Tests; Female; Gentamicins; Humans; Male; Middle Aged; Neuroma, Acoustic; Posto | 2016 |
Vertigo Perception and Quality of Life in Patients after Surgical Treatment of Vestibular Schwannoma with Pretreatment Prehabituation by Chemical Vestibular Ablation.
Topics: Adult; Aged; Caloric Tests; Female; Gentamicins; Humans; Male; Middle Aged; Neuroma, Acoustic; Posto | 2016 |
Intratympanal gentamicin in Meniere's disease: Effects on individual semicircular canals.
Topics: Adult; Female; Gentamicins; Head Impulse Test; Humans; Injection, Intratympanic; Male; Meniere Disea | 2018 |
Transtympanic gentamicin treatment using Silverstein MicroWick in Ménière's disease patients: long term outcome.
Topics: Adult; Aged; Anti-Bacterial Agents; Drug Delivery Systems; Ear, Middle; Female; Gentamicins; Hearing | 2009 |
Gentamicin injections for Ménière disease: comparison of subjective and objective end points.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Female; Gentamicins; Health Status Indicators | 2008 |
Hearing results following intratympanic gentamicin perfusion for Ménière's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry, Pure-Tone; Female; Ge | 2009 |
Contemporary role of endolymphatic mastoid shunt surgery in the era of transtympanic perfusion strategies.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Ear, Inner; Endolymphatic Shunt; Female; Follow-Up S | 2008 |
Tenotomy of the tensor tympani and stapedius tendons in Ménière's disease.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Dizziness; Ear, Middle; Female; Gentamicins; Humans; | 2009 |
High-dose intratympanic gentamicin instillations for treatment of Meniere's disease: long-term results.
Topics: Adult; Aged; Female; Follow-Up Studies; Gentamicins; Hearing Loss; Humans; Male; Meniere Disease; Mi | 2009 |
Vestibular function and vertigo control after intratympanic gentamicin for Ménière's disease.
Topics: Anti-Bacterial Agents; Caloric Tests; Chi-Square Distribution; Databases, Factual; Drug Administrati | 2009 |
Intratympanic gentamicin treatment of patients with Ménière's disease with normal hearing.
Topics: Adult; Aged; Aged, 80 and over; Audiometry; Audiometry, Pure-Tone; Caloric Tests; Electronystagmogra | 2010 |
Evidence-based modification of intratympanic gentamicin injections in patients with intractable vertigo.
Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Biological Availability; Ear, Middle; Gentamic | 2010 |
Outcomes of endolymphatic shunt surgery for Ménière's disease: comparison with intratympanic gentamicin on vertigo control and hearing loss.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Chi-Square Distribution; Ear, Inner; Endo | 2010 |
Results of electrocochleography in Ménière's disease after successful vertigo control by single intratympanic gentamicin injection.
Topics: Adult; Aged; Aged, 80 and over; Audiometry, Evoked Response; Audiometry, Pure-Tone; Cochlea; Female; | 2011 |
Intratympanic gentamicin injections for the treatment of Ménière's disease.
Topics: Adult; Aged; Aged, 80 and over; Audiometry, Pure-Tone; Female; Gentamicins; Hearing Disorders; Human | 2010 |
Cochlear function in Ménière's disease.
Topics: Adult; Aged; Aged, 80 and over; Audiometry, Evoked Response; Cochlea; Female; Gentamicins; Humans; I | 2012 |
The use of intratympanic gentamicin in patients with vestibular schwannoma and disabling vertigo.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry, Pure-Tone; Caloric Tests; Female; Gentam | 2013 |
Benign paroxysmal positional vertigo in patients with Ménière's disease treated with intratympanic gentamycin.
Topics: Adult; Aged; Anti-Bacterial Agents; Female; Follow-Up Studies; Gentamicins; Humans; Male; Meniere Di | 2002 |
Efficacy of increased gentamicin concentration for intratympanic injection therapy in Ménière's disease.
Topics: Caloric Tests; Deafness; Dose-Response Relationship, Drug; Female; Gentamicins; Hearing; Humans; Inj | 2002 |
[Intra-tympanic gentamicin in the treatment of Ménière's disease: preliminary results ].
Topics: Adult; Audiometry, Pure-Tone; Audiometry, Speech; Drug Evaluation; Ear, Middle; Female; Gentamicins; | 2002 |
Changes in the three-dimensional angular vestibulo-ocular reflex following intratympanic gentamicin for Ménière's disease.
Topics: Adult; Aged; Cold Temperature; Female; Gentamicins; Head; Humans; Male; Meniere Disease; Middle Aged | 2002 |
Long-term hearing outcome in patients receiving intratympanic gentamicin for Ménière's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Female; Follow-Up Studies; Gentamicins; H | 2003 |
[Intratympanic gentamicin treatment for intractable Menière's disease].
Topics: Anti-Bacterial Agents; Female; Follow-Up Studies; Gentamicins; Humans; Injections; Male; Meniere Dis | 2004 |
Vestibular nerve section versus intratympanic gentamicin for Meniere's disease.
Topics: Anti-Bacterial Agents; Audiometry, Pure-Tone; Gentamicins; Humans; Injections; Meniere Disease; Post | 2004 |
Inner ear changes with intracochlear gentamicin administration in Guinea pigs.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Cochlea; Cytoplasm; Drug Administration Rou | 2004 |
[Intratympanic gentamicin in Menière's disease].
Topics: Adult; Audiometry, Pure-Tone; Auditory Threshold; Ear, Middle; Female; Follow-Up Studies; Gentamicin | 2004 |
Long-term results of gentamicin inner ear perfusion in Ménière's disease.
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Caloric Tests; Catheters, Indwelling; D | 2004 |
Intratympanic gentamicin in monolateral Meniere's disease: our experience.
Topics: Adult; Aged; Anti-Bacterial Agents; Ear, Middle; Female; Gentamicins; Humans; Injections; Male; Meni | 2006 |
[Long-term results of transtympanic gentamicin treatment in Meniere's disease].
Topics: Adult; Anti-Bacterial Agents; Female; Follow-Up Studies; Gentamicins; Hearing; Humans; Injections; M | 2005 |
VEMPs and dynamic posturography after intratympanic gentamycin in Menière's disease.
Topics: Adult; Aged; Evoked Potentials, Auditory; Female; Gentamicins; Humans; Male; Meniere Disease; Middle | 2005 |
Angular vestibulo-ocular reflex gains correlate with vertigo control after intratympanic gentamicin treatment for Meniere's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Caloric Tests; Gentamicins; Humans; Injections, Intralesional; M | 2005 |
Intratympanic gentamicin treatment after endolymphatic sac surgery.
Topics: Adult; Aged; Audiometry, Pure-Tone; Auditory Threshold; Ear, Middle; Electronystagmography; Endolymp | 2005 |
[Vertigo attacks -- current therapy].
Topics: Acetazolamide; Adult; Aged; Betahistine; Dexamethasone; Ear, Middle; Gentamicins; Humans; Injections | 2005 |
Outcomes in the use of intra-tympanic gentamicin in the treatment of Ménière's disease.
Topics: Anti-Bacterial Agents; Female; Gelatin Sponge, Absorbable; Gentamicins; Hearing Loss; Humans; Male; | 2006 |
Drop attacks and vertical vertigo after transtympanic gentamicin: diagnosis and management.
Topics: Administration, Topical; Aged; Female; Gentamicins; Humans; Meniere Disease; Paralysis; Syncope; Tym | 2005 |
Factors relating to the vertigo control and hearing changes following intratympanic gentamicin for intractable Ménière's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Evoked Response; Female; Gentamicins; Hearing Loss; | 2006 |
Intratympanic gentamicin treatment in Meniere's disease: patients' experiences and outcomes.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry, Pure-Tone; Auditory Threshold; Fe | 2006 |
Gentamicin ototoxicity: clinical features and the effect on the human vestibulo-ocular reflex.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Female; Gentamicins; Head Movements; Humans; | 2006 |
Long-term follow-up after gentamicin application via the Silverstein MicroWick in the treatment of Ménière's disease.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug Delivery System | 2006 |
Histopathology of the vestibular end organs after intratympanic gentamicin failure for Meniere's disease.
Topics: Administration, Topical; Anti-Bacterial Agents; Atrophy; Ear, Inner; Gentamicins; Hair Cells, Audito | 2007 |
Low dose transtympanic gentamicin treatment for intractable Meniere's disease: a prospective study.
Topics: Anti-Bacterial Agents; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Aged; Prospective | 2007 |
[The effects of small dose of intratympanic gentamicin injection on intractable Meniere's disease].
Topics: Adolescent; Adult; Aged; Ear, Middle; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Age | 2007 |
Long-term vertigo control in patients after intratympanic gentamicin instillation for Ménière's disease.
Topics: Adult; Anti-Bacterial Agents; Caloric Tests; Dizziness; Drug Implants; Ear, Middle; Electronystagmog | 2007 |
[Treatment of Ménière's disease with intratympanically applied gentamycin sulphate (author's transl)].
Topics: Ear, Middle; Female; Gentamicins; Humans; Male; Meniere Disease; Tinnitus; Vertigo | 1982 |
[The indications for middle ear instillation of gentamicin in Menière's disease (author's transl)].
Topics: Ear, Middle; Gentamicins; Humans; Meniere Disease; Tinnitus; Vertigo | 1981 |
Pharmacologic labyrinthectomy.
Topics: Aminoglycosides; Ear, Inner; Gentamicins; Humans; Meniere Disease; Streptomycin; Vertigo | 1994 |
Surgical treatment of vertigo--the Karolinska Hospital policy.
Topics: Adult; Aged; Anti-Bacterial Agents; Endolymphatic Sac; Female; Follow-Up Studies; Gentamicins; Human | 1996 |
Intratympanic gentamicin therapy for Ménière's disease.
Topics: Adult; Aged; Audiometry, Pure-Tone; Auditory Threshold; Female; Gentamicins; Hearing Disorders; Huma | 1997 |
Intratympanic gentamicin in Ménière's disease: results of therapy.
Topics: Adult; Aged; Audiometry, Pure-Tone; Caloric Tests; Ear, Inner; Female; Gentamicins; Hearing Disorder | 1997 |
Low-dose intratympanic gentamicin and the treatment of Meniere's disease: preliminary results.
Topics: Absorption; Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Elec | 1997 |
When and how to use gentamicin in the treatment of Menière's disease.
Topics: Anti-Bacterial Agents; Gentamicins; Humans; Meniere Disease; Vertigo | 1997 |
Do aminoglycoside otic preparations cause ototoxicity in the presence of tympanic membrane perforations?
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Ear, Inner; Female; Gentamicins; Hearin | 1997 |
Transtympanic gentamicin in the treatment of Meniére's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Endolymphatic Hydrops; Follow-Up Studies; Gentamicins; Humans; M | 1997 |
Treatment of intractable Menière's disease with intratympanic gentamicin: review of the University of Ottawa experience.
Topics: Auditory Threshold; Ear, Middle; Female; Follow-Up Studies; Gentamicins; Humans; Infusions, Parenter | 1997 |
Intratympanic gentamicin treatment for Meniere's disease.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry, Pure-Ton | 1998 |
Intratympanic gentamicin in Meniere's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Chi-Square Distribution; Electronystagmog | 1998 |
Intratympanic gentamicin injection for the treatment of Meniere's disease.
Topics: Anti-Bacterial Agents; Caloric Tests; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Age | 1998 |
Unilateral vestibulotoxicity due to systemic gentamicin therapy.
Topics: Aged; Anti-Bacterial Agents; Caloric Tests; Female; Gentamicins; Humans; Male; Middle Aged; Vertigo; | 1998 |
Subjective visual horizontal during follow-up after unilateral vestibular deafferentation with gentamicin.
Topics: Afferent Pathways; Anti-Bacterial Agents; Caloric Tests; Electrooculography; Female; Follow-Up Studi | 1998 |
Postural compensation after intratympanic gentamicin treatment of Menière's disease.
Topics: Adult; Aged; Female; Follow-Up Studies; Gentamicins; Humans; Locomotion; Male; Meniere Disease; Midd | 1999 |
Intratympanic gentamicin titration therapy for intractable Meniere's disease.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Caloric Tests; Dose-Response Relationship, Dr | 1999 |
Ototoxicity of topical gentamicin preparations.
Topics: Administration, Topical; Adult; Aged; Ear, Inner; Female; Gentamicins; Hearing Disorders; Humans; Ma | 1999 |
Intratympanic therapy for Ménière's disease. High-concentration gentamicin with round-window protection.
Topics: Adult; Anti-Bacterial Agents; Ear, Middle; Female; Follow-Up Studies; Gentamicins; Hearing; Humans; | 1999 |
Round window gentamicin mu-catheter--a new therapeutic tool in Ménière's disease.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Catheterization; Equipment Design; Female; Ge | 2000 |
Continuous intratympanic infusion of gentamicin via a microcatheter in Menière's disease.
Topics: Administration, Topical; Anti-Bacterial Agents; Auditory Threshold; Caloric Tests; Catheterization; | 2001 |
Unpredictable hearing loss after intratympanic gentamicin treatment for vertigo. A new theory.
Topics: Adult; Aged; Anti-Bacterial Agents; Deafness; Female; Gentamicins; Humans; Male; Meniere Disease; Ve | 2001 |
Long-term follow-up of transtympanic gentamicin for Ménière's syndrome.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry, Pure-Tone; Drug Administration Ro | 2001 |
Patients' subjective evaluations of quality of life related to disease-specific symptoms, sense of coherence, and treatment in Ménière's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Cross-Sectional Studies; Endolymphatic Sac; Female; Gentamicins; | 2001 |
Ménière's disease in childhood.
Topics: Adolescent; Anti-Bacterial Agents; Child; Deafness; Female; Gentamicins; Hearing Tests; Humans; Meni | 2001 |
Microdose gentamicin administration via the round window microcatheter: results in patients with Meniere's disease.
Topics: Adult; Aged; Audiometry; Audiometry, Evoked Response; Catheterization; Female; Gentamicins; Humans; | 2001 |
Intratympanic gentamicin therapy for persistent vertigo after endolymphatic sac surgery.
Topics: Administration, Topical; Adult; Anti-Bacterial Agents; Audiometry, Pure-Tone; Electronystagmography; | 2002 |
Vertical eye-movement oscillation with a frequency double that of lateral linear acceleration in patients with long-standing unilateral vestibular loss.
Topics: Adult; Anti-Bacterial Agents; Case-Control Studies; Eye Movements; Female; Gentamicins; Humans; Male | 2002 |
Low-dose intratympanic gentamicin treatment of Menière's disease.
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Caloric Tests; Drug Administration Sche | 1994 |
Continuous gentamicin therapy using an IntraEAR microcatheter for Meniere's disease: a retrospective study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Catheterization; Female; Follow-Up Studies; G | 2002 |
Changes in the angular vestibulo-ocular reflex after a single dose of intratympanic gentamicin for Ménière's disease.
Topics: Functional Laterality; Gentamicins; Humans; Injections; Meniere Disease; Reflex, Vestibulo-Ocular; T | 2002 |
Vestibular nerve section in a child with intractable Menière's disease.
Topics: Anti-Bacterial Agents; Child, Preschool; Ear, Middle; Gentamicins; Hearing; Humans; Male; Meniere Di | 2002 |
[The intratympanic treatment of Menière's disease with ototoxic antibiotics. A follow-up study of 55 cases (author's transl)].
Topics: Caloric Tests; Ear, Middle; Gentamicins; Hearing Disorders; Humans; Meniere Disease; Streptomycin; V | 1977 |
Chemical labyrinthectomy: local application of gentamicin for the treatment of unilateral Menière's disease.
Topics: Adult; Aged; Female; Follow-Up Studies; Gentamicins; Hearing; Humans; Instillation, Drug; Male; Meni | 1992 |
Delayed onset of ototoxic effects of gentamicin in patients with Meniére's disease.
Topics: Adult; Audiometry, Pure-Tone; Caloric Tests; Cochlea; Electrooculography; Female; Gentamicins; Human | 1991 |
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease.
Topics: Adult; Gentamicins; Hearing Disorders; Humans; Meniere Disease; Middle Aged; Nystagmus, Pathologic; | 1991 |
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy.
Topics: Adult; Caloric Tests; Cochlea; Dizziness; Gentamicins; Humans; Instillation, Drug; Meniere Disease; | 1991 |
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy.
Topics: Adult; Caloric Tests; Cochlea; Dizziness; Gentamicins; Humans; Instillation, Drug; Meniere Disease; | 1991 |
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy.
Topics: Adult; Caloric Tests; Cochlea; Dizziness; Gentamicins; Humans; Instillation, Drug; Meniere Disease; | 1991 |
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy.
Topics: Adult; Caloric Tests; Cochlea; Dizziness; Gentamicins; Humans; Instillation, Drug; Meniere Disease; | 1991 |
Aminoglycoside therapy and toxicity in the elderly.
Topics: Aged; Amikacin; Dizziness; Gentamicins; Glomerulonephritis; Hearing Disorders; Humans; Tinnitus; Ver | 1987 |
Topical gentamicin-induced positional vertigo.
Topics: Administration, Topical; Ataxia; Gentamicins; Humans; Male; Middle Aged; Posture; Time Factors; Vert | 1985 |
[Gentamicin and auricular toxicity].
Topics: Adult; Animals; Audiometry; Deafness; Ear Diseases; Ear, Inner; Female; Gentamicins; Guinea Pigs; Hi | 1969 |
The dizzy patient.
Topics: Diazepam; Drainage; Ear; Ear Neoplasms; Ethacrynic Acid; Gentamicins; Hearing Disorders; Humans; Inf | 1972 |
Untoward effects of antimicrobial agents on major organ systems.
Topics: Agranulocytosis; Amphotericin B; Anemia, Aplastic; Anemia, Hemolytic; Anti-Bacterial Agents; Ataxia; | 1974 |
Retrospective study of the ototoxicity of gentamicin.
Topics: Adult; Age Factors; Aged; Creatinine; Dose-Response Relationship, Drug; Electrooculography; Gentamic | 1973 |
Prospective study of the ototoxicity of gentamicin.
Topics: Adult; Age Factors; Aged; Creatinine; Electrooculography; Gentamicins; Hearing Disorders; Humans; Ki | 1973 |
The ototoxicity of gentamicin.
Topics: Age Factors; Aged; Body Temperature; Cochlea; Creatinine; Electrooculography; Female; Gentamicins; H | 1973 |
Vertigo and its treatment.
Topics: Air Pressure; Anxiety; Brain Diseases; Cardiovascular Diseases; Cervical Vertebrae; Ear Diseases; Et | 1974 |
[Kidney insufficiency after treatment with the antibiotic drug combination cephalothin-gentamicin].
Topics: Acute Kidney Injury; Administration, Oral; Aged; Cephalothin; Creatinine; Drug Synergism; Drug Thera | 1974 |
Ototoxic effects of gentamicin.
Topics: Audiometry; Calorimetry; Cochlea; Gentamicins; Hearing Disorders; Humans; Pyelonephritis; Uremia; Ve | 1970 |