gentamicin has been researched along with Uremia in 29 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Before applying PD, temporary aggravation of uremia was induced by administration of gentamicin (10 mg/kg i." | 4.12 | A Uremic Pig Model for Peritoneal Dialysis. ( Ahmed, S; de Kort, GAP; de Vries, JC; Gerritsen, KGF; Hazenbrink, DHM; Joles, JA; Monninkhof, AS; Nguyen, TQ; Vaessen, KRD; van Gelder, MK; Verhaar, MC; Vonken, EPA, 2022) |
| "Sera of dogs with gentamicin-induced uremia were analyzed by high performance liquid chromatography system with strongly basic macroreticular anion exchange resin." | 3.68 | Detection of uremic peaks in dogs by anion exchange high performance liquid chromatography. ( Kawamura, M; Murakami, F; Nishimura, R; Ohashi, F; Sasaki, N; Takai, N; Takeuchi, A, 1992) |
| "Continuous infusions of gentamicin, amikacin or sisomicin combined with carbenicillin were compared in a randomized study in the treatment of 572 febrile episodes in 281 patients with cancer." | 2.65 | A randomized comparative trial of three aminoglycosides--comparison of continuous infusions of gentamicin, amikacin and sisomicin combined with carbenicillin in the treatment of infections in neutropenic patients with malignancies. ( Bodey, GP; Keating, MJ; Rodriguez, V; Valdivieso, M, 1979) |
| "Gentamicin-treated rats showed marked elevation of blood urea nitrogen, extensive tubular necrosis in the kidney and haemosiderin deposition in the spleen." | 1.28 | Effect of recombinant human erythropoietin on new anaemic model rats induced by gentamicin. ( Arai, H; Koumegawa, J; Kusaka, M; Nagano, N; Wada, M, 1990) |
| "Gentamicin was significantly removed by peritoneal dialysis with a clearance value of 9." | 1.28 | Dosing regimen of gentamicin during intermittent peritoneal dialysis. ( Arkaravichien, W; Indraprasit, S; Kaojarern, S; Pummangura, C, 1989) |
| "Gentamicin was administered subcutaneously to sexually immature (1400 to 1800 gm) or sexually mature (3800 to 4600 gm) New Zealand White rabbits in a dose of 15 mg/kg twice a day." | 1.27 | Effect of gentamicin on isolated glomeruli and proximal tubules of the rabbit. ( Chonko, A; Cuppage, F; Hodges, G; Karniski, L; Savin, V, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (79.31) | 18.7374 |
| 1990's | 4 (13.79) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (3.45) | 24.3611 |
| 2020's | 1 (3.45) | 2.80 |
| Authors | Studies |
|---|---|
| de Vries, JC | 1 |
| van Gelder, MK | 1 |
| Monninkhof, AS | 1 |
| Ahmed, S | 1 |
| Hazenbrink, DHM | 1 |
| Nguyen, TQ | 1 |
| de Kort, GAP | 1 |
| Vonken, EPA | 1 |
| Vaessen, KRD | 1 |
| Joles, JA | 1 |
| Verhaar, MC | 1 |
| Gerritsen, KGF | 1 |
| Nagib, EM | 1 |
| El-Sayed, MH | 1 |
| Ahmed, MA | 1 |
| Youssef, MH | 1 |
| Mates, A | 1 |
| Wolkoff, D | 1 |
| Nagy, A | 1 |
| Vécsei, B | 1 |
| Horpácsy, G | 1 |
| Baradnay, G | 1 |
| Kahn, T | 1 |
| Bosch, J | 1 |
| Wiener, P | 1 |
| Dikman, S | 1 |
| Mealey, KL | 1 |
| Boothe, DM | 1 |
| Johnson, JH | 1 |
| Wolf, AM | 1 |
| Johnson, TL | 1 |
| Jensen, JM | 1 |
| Shanson, DC | 1 |
| Kensit, J | 1 |
| Hince, C | 1 |
| Broughall, JM | 1 |
| Pugsley, DJ | 1 |
| Reeves, DS | 1 |
| Stessman, J | 2 |
| Michel, J | 2 |
| Sacke, T | 1 |
| Keating, MJ | 1 |
| Bodey, GP | 2 |
| Valdivieso, M | 1 |
| Rodriguez, V | 2 |
| Myers, DR | 1 |
| DeFehr, J | 1 |
| Bennet, WM | 1 |
| Porter, GA | 1 |
| Olsen, GD | 1 |
| Sacks, T | 1 |
| Leroy, A | 1 |
| Humbert, G | 1 |
| Oksenhendler, G | 1 |
| Fillastre, JP | 2 |
| Kawamura, M | 1 |
| Ohashi, F | 1 |
| Murakami, F | 1 |
| Takai, N | 1 |
| Nishimura, R | 1 |
| Sasaki, N | 1 |
| Takeuchi, A | 1 |
| Nagano, N | 1 |
| Koumegawa, J | 1 |
| Arai, H | 1 |
| Wada, M | 1 |
| Kusaka, M | 1 |
| Kaojarern, S | 2 |
| Arkaravichien, W | 1 |
| Indraprasit, S | 2 |
| Pummangura, C | 2 |
| Zager, RA | 1 |
| Prior, RB | 1 |
| Ukaravichien, V | 1 |
| Golper, TA | 1 |
| Saad, AM | 1 |
| Savin, V | 1 |
| Karniski, L | 1 |
| Cuppage, F | 1 |
| Hodges, G | 1 |
| Chonko, A | 1 |
| Helm, E | 1 |
| Stille, W | 1 |
| Dubois, D | 1 |
| Robert, M | 1 |
| Federspil, P | 1 |
| Schöndorf, T | 1 |
| Hey, D | 1 |
| Meyers, RM | 1 |
| Lange, G | 1 |
| Chisholm, GD | 1 |
1 trial available for gentamicin and Uremia
| Article | Year |
|---|---|
A randomized comparative trial of three aminoglycosides--comparison of continuous infusions of gentamicin, amikacin and sisomicin combined with carbenicillin in the treatment of infections in neutropenic patients with malignancies.
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Carbenicillin; Drug Therapy, Combination; F | 1979 |
28 other studies available for gentamicin and Uremia
| Article | Year |
|---|---|
A Uremic Pig Model for Peritoneal Dialysis.
Topics: Animals; Creatinine; Dialysis Solutions; Gentamicins; Peritoneal Dialysis; Phosphates; Swine; Urea; | 2022 |
Intestinal motility in acute uremia and effects of erythropoietin.
Topics: Acute Disease; Animals; Colon; Creatinine; Disease Models, Animal; Duodenum; Erythropoietin; Female; | 2012 |
A simple method for determining gentamicin blood levels.
Topics: Anti-Bacterial Agents; Biological Assay; Gentamicins; Humans; Microbial Sensitivity Tests; Staphyloc | 1983 |
[Changes in kidney function in patients with colon tumors treated with nephrotoxic antibiotics].
Topics: Antibiotics, Antineoplastic; Colonic Neoplasms; Gentamicins; Humans; Kidney; Kidney Function Tests; | 1981 |
Course of gentamicin nephrotoxicity.
Topics: Animals; Blood Urea Nitrogen; Body Weight; Creatinine; Electrolytes; Gentamicins; Hematocrit; Kidney | 1980 |
Nephrotoxicosis associated with topical administration of gentamicin in a cat.
Topics: Abscess; Administration, Topical; Animals; Cat Diseases; Cats; Debridement; Drug Overdose; Female; G | 1994 |
Gentamicin toxicosis in a North American cougar.
Topics: Alopecia; Animals; Anorexia; Bites and Stings; Carnivora; Drug Overdose; Gentamicins; Kidney; Male; | 1993 |
Letter: Uraemia, gram-negative sepsis, and gentamicin assays.
Topics: Biological Assay; Culture Media; Evaluation Studies as Topic; Gentamicins; Humans; Sepsis; Urea; Ure | 1975 |
Letter: Potential pitfall in bioassay of serum-gentamicin.
Topics: Biological Assay; Diagnostic Errors; Gentamicins; Humans; Uremia | 1975 |
Letter: Potential pitfalls in bioassay of serum-gentamicin.
Topics: Biological Assay; Gentamicins; Humans; Uremia | 1976 |
Gentamicin binding to serum and plasma proteins.
Topics: Blood Proteins; Calcium; Gentamicins; Heparin; Humans; In Vitro Techniques; Magnesium; Plasma; Prote | 1978 |
Error in recovery rate of aminoglycosides from uraemic sera.
Topics: Aminoglycosides; Biological Assay; Gentamicins; Humans; Kanamycin; Streptomycin; Tobramycin; Uremia | 1977 |
Comparative pharmacokinetics of lividomycin, amikacin and sisomicin in normal subjects and in uraemic patients.
Topics: Adult; Amikacin; Biological Assay; Gentamicins; Half-Life; Humans; Kanamycin; Kinetics; Middle Aged; | 1976 |
Detection of uremic peaks in dogs by anion exchange high performance liquid chromatography.
Topics: Animals; Anion Exchange Resins; Chromatography, High Pressure Liquid; Dog Diseases; Dogs; Female; Ge | 1992 |
Effect of recombinant human erythropoietin on new anaemic model rats induced by gentamicin.
Topics: Anemia; Animals; Blood Volume; Erythropoietin; Gentamicins; Hematocrit; Kidney Tubular Necrosis, Acu | 1990 |
Dosing regimen of gentamicin during intermittent peritoneal dialysis.
Topics: Gentamicins; Humans; Peritoneal Dialysis; Uremia | 1989 |
Gentamicin and gram-negative bacteremia. A synergism for the development of experimental nephrotoxic acute renal failure.
Topics: Acute Kidney Injury; Animals; Blood Pressure; Drug Synergism; Endotoxins; Escherichia coli; Female; | 1986 |
Gentamicin removal during intermittent peritoneal dialysis.
Topics: Creatinine; Gentamicins; Humans; Kinetics; Peritoneal Dialysis; Peritoneum; Urea; Uremia | 1986 |
Gentamicin and phenytoin sieving through hollow-fiber polysulfone hemofilters.
Topics: Blood; Blood Flow Velocity; Blood Proteins; Gentamicins; Humans; Mathematics; Phenytoin; Polymers; P | 1986 |
Effect of gentamicin on isolated glomeruli and proximal tubules of the rabbit.
Topics: Aging; Animals; Creatinine; Female; Gentamicins; Glomerular Filtration Rate; Kidney Cortex; Kidney G | 1985 |
[Clinical and therapeutic features of pseudomonas aeruginosa septicaemia].
Topics: Adult; Aged; Agranulocytosis; Bacteria; Carbenicillin; Catheterization; Colistin; Diabetes Complicat | 1972 |
Advances in the management of Pseudomonas aeruginosa infections in cancer patients.
Topics: Carbenicillin; Colistin; Ecthyma; Gentamicins; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Menin | 1973 |
[Renal tolerance of gentamicin].
Topics: Animals; Cats; Dogs; Drug Tolerance; Gentamicins; Humans; Kidney Diseases; Necrosis; Rats; Uremia | 1974 |
[Experimental studies on the ototoxicity of uremia].
Topics: Animals; Anti-Bacterial Agents; Cochlea; Diuretics; Gentamicins; Guinea Pigs; Hearing Disorders; Ure | 1973 |
[Pathogenesis of bleeding diathesis in Weil's disease].
Topics: Adult; Antigens; Bilirubin; Cephalothin; Complement Fixation Tests; Disseminated Intravascular Coagu | 1974 |
Ototoxic effects of gentamicin.
Topics: Audiometry; Calorimetry; Cochlea; Gentamicins; Hearing Disorders; Humans; Pyelonephritis; Uremia; Ve | 1970 |
[Gentamycin induced lesions of the vestibular organ in guinea pigs(cytovestibulogram calorization) and after its therapeutic administration].
Topics: Adult; Animals; Calorimetry; Female; Gentamicins; Glomerulonephritis; Guinea Pigs; Humans; Labyrinth | 1970 |
Distribution and dosage of antibacterial agents in patients with normal and impaired renal function.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Diffusion; Gentamicins; Humans; Kidney; Kidne | 1970 |