Page last updated: 2024-10-27

gentamicin and Tularemia

gentamicin has been researched along with Tularemia in 40 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Tularemia: A plague-like disease of rodents, transmissible to man. It is caused by FRANCISELLA TULARENSIS and is characterized by fever, chills, headache, backache, and weakness.

Research Excerpts

ExcerptRelevanceReference
"Because of the recent lack of availability of streptomycin--currently considered the drug of choice for the treatment of tularemia--we reviewed the literature on alternative drugs that have been used for this purpose."8.79Streptomycin and alternative agents for the treatment of tularemia: review of the literature. ( Cross, JT; Enderlin, G; Jacobs, RF; Morales, L, 1994)
"An alternative to streptomycin for treatment of possible tularemia would be useful on occasions when a patient develops a perplexing pneumonia that does not respond to initial treatment."7.66Treatment of tularemia, including pulmonary tularemia, with gentamicin. ( Bates, JH; Eigelsbach, HT; Little, SF; Mason, WL, 1980)
"A first-line therapy for treating tularemia is aminoglycosides (streptomycin or, more commonly, gentamicin), and treatment duration is typically 7 to 10 days, with longer courses for more severe cases."6.76Treatment failure of gentamicin in pediatric patients with oropharyngeal tularemia. ( Cevit, Ö; Engin, A; Gültürk, A; Güven, AS; İçağasıoğlu, FD; Kaya, A; Uysal, IÖ, 2011)
"We describe a patient with ulceroglandular tularemia who initially responded to therapy with gentamicin but then clinically relapsed."4.79Relapse of tularemia after aminoglycoside therapy: case report and discussion of therapeutic options. ( Pombo, DJ; Risi, GF, 1995)
"Because of the recent lack of availability of streptomycin--currently considered the drug of choice for the treatment of tularemia--we reviewed the literature on alternative drugs that have been used for this purpose."4.79Streptomycin and alternative agents for the treatment of tularemia: review of the literature. ( Cross, JT; Enderlin, G; Jacobs, RF; Morales, L, 1994)
"An alternative to streptomycin for treatment of possible tularemia would be useful on occasions when a patient develops a perplexing pneumonia that does not respond to initial treatment."3.66Treatment of tularemia, including pulmonary tularemia, with gentamicin. ( Bates, JH; Eigelsbach, HT; Little, SF; Mason, WL, 1980)
"A first-line therapy for treating tularemia is aminoglycosides (streptomycin or, more commonly, gentamicin), and treatment duration is typically 7 to 10 days, with longer courses for more severe cases."2.76Treatment failure of gentamicin in pediatric patients with oropharyngeal tularemia. ( Cevit, Ö; Engin, A; Gültürk, A; Güven, AS; İçağasıoğlu, FD; Kaya, A; Uysal, IÖ, 2011)
"Why tularemia is prevalent on Martha's Vineyard and why it commonly presents as a pneumonic disease there remain undescribed."2.44Pneumonic tularemia on Martha's Vineyard: clinical, epidemiologic, and ecological characteristics. ( Matyas, BT; Nieder, HS; Telford, SR, 2007)
"Of the 230 patients treated for tularemia, 36 (16%) were children with a median age of 9."1.72Tularemia in children during the last outbreak in Kosovo. ( Hyseni, S; Namani, S; Ndrejaj Berisha, V; Ponosheci Biçaku, A; Sadiku, I, 2022)
"Given the limited antibiotics for treating tularemia and the possible use of antibiotic-resistant strains as a biowarfare agent, new antibacterial agents are needed."1.43Needle-Free Delivery of Acetalated Dextran-Encapsulated AR-12 Protects Mice from Francisella tularensis Lethal Challenge. ( Ainslie, KM; Bachelder, EM; Borteh, H; Collier, MA; Curry, H; Gunn, JS; Hoang, KV; Schlesinger, LS, 2016)
"Tularemia is a bacterial zoonotic disease that is caused by Francisella tularensis and among the infectious reasons that cause fever of unknown origin (FUO) in children."1.39Unusual presentatıon of oropharyngeal tularemıa: a case report. ( Kara, SS; Polat, M; Tapısız, A; Tezer, H, 2013)
"Tularemia is a zoonotic disease of the northern hemisphere."1.39A case of oculoglandular tularemia resistant to medical treatment. ( Akcakaya, N; Akil, F; Camcioglu, Y; Cokugras, H; Kilic, O; Kosker, M; Ozturk, O; Sener, D; Yilmaz, M, 2013)
"treatment with gentamicin and IL-12 therapeutically at 8 and 24 h after challenge markedly enhanced the rate of survival (70 to 100%) against pulmonary infection compared to the rates of survival for animals treated with antibiotic alone (17%) or IL-12 alone (0%)."1.32Intranasal interleukin-12 treatment promotes antimicrobial clearance and survival in pulmonary Francisella tularensis subsp. novicida infection. ( Arulanandam, BP; Budhavarapu, VN; Klose, KE; Pammit, MA; Raulie, EK; Teale, JM, 2004)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-19904 (10.00)18.7374
1990's9 (22.50)18.2507
2000's7 (17.50)29.6817
2010's18 (45.00)24.3611
2020's2 (5.00)2.80

Authors

AuthorsStudies
Sadiku, I1
Namani, S1
Ndrejaj Berisha, V1
Ponosheci Biçaku, A1
Hyseni, S1
Nemmour, A1
Bakri, A1
Fischer, CA1
Brand, Y1
Stringham, S1
Green Hines, A1
Attebery, J1
Darwin, L1
Wachholtz, A1
Deschamp, A1
Choudhry, O1
Neemann, K1
Calin, R1
Caumes, E1
Reibel, F1
Ali Mohamed, A1
Brossier, F1
Foltz, V1
Boussouar, S1
Fautrel, B1
Maurin, M1
Katlama, C1
Pourcher, V1
Anand, N1
Deochand, O1
Murphy, R1
Drago, F1
Javor, S1
Parodi, A1
Polat, M1
Kara, SS1
Tapısız, A1
Tezer, H1
Bloch, C1
Friedl, A1
Zucol, F1
Widmer, A1
Khanna, N1
Kosker, M1
Sener, D1
Kilic, O1
Akil, F1
Yilmaz, M1
Ozturk, O1
Cokugras, H1
Camcioglu, Y1
Akcakaya, N1
Harik, NS1
Yilmaz, GR1
Guven, T1
Guner, R1
Kilic, S1
Gulen, TA1
Eser, FC1
Tasyaran, MA1
Saadah, H1
Uzun, MÖ1
Yanik, K1
Erdem, M1
Kostakoglu, U1
Yilmaz, G1
Tanriverdi Çayci, Y1
Lindgren, H1
Sjöstedt, A1
Hoang, KV1
Curry, H1
Collier, MA1
Borteh, H1
Bachelder, EM1
Schlesinger, LS1
Gunn, JS1
Ainslie, KM1
Snowden, J1
Stovall, S1
Kaya, A1
Uysal, IÖ1
Güven, AS1
Engin, A1
Gültürk, A1
İçağasıoğlu, FD1
Cevit, Ö1
Faucon, AL1
Zamfir, O1
Dupouët, L1
Pruna, A1
Sutherland, MD1
Goodyear, AW1
Troyer, RM1
Chandler, JC1
Dow, SW1
Belisle, JT1
Jackson, J1
McGregor, A1
Cooley, L1
Ng, J1
Brown, M1
Ong, CW1
Darcy, C1
Sintchenko, V1
Eppes, SC1
Pammit, MA1
Budhavarapu, VN1
Raulie, EK1
Klose, KE1
Teale, JM1
Arulanandam, BP1
Hassoun, A1
Spera, R1
Dunkel, J1
Mitchell, LA1
Bradsher, RW2
Paden, TC1
Malak, SF1
Warmack, TS1
Nazarian, SM1
Fitzgerald, RT1
Bansal, D1
Carrouth, DA1
Khan, MA1
Shah, SV1
Karabay, O1
Yilmaz, F1
Gurcan, S1
Goksugur, N1
Matyas, BT1
Nieder, HS1
Telford, SR1
Charles, P1
Stumpf, P1
Buffet, P1
Hot, A1
Lecuit, M1
Dupont, B1
Lortholary, O1
Consigny, PH1
Evans, ME1
McGee, ZA1
Hunter, PT1
Schaffner, W1
Mason, WL1
Eigelsbach, HT1
Little, SF1
Bates, JH1
Risi, GF1
Pombo, DJ1
Cross, JT2
Schutze, GE2
Jacobs, RF3
Garver, MK1
St Geme, JW1
Siegel, MJ1
Enderlin, G1
Morales, L1
Scheel, O1
Hoel, T1
Sandvik, T1
Berdal, BP1
Capellan, J1
Fong, IW1
Rodgers, BL1
Duffield, RP1
Taylor, T1
Steinemann, TL1
Sheikholeslami, MR1
Brown, HH1
Jackson, RT1
Lester, JP1
Marcus, DM1
Frederick, AR1
Hodges, T1
Allan, JD1
Albert, DM1
Alford, RH1
John, JT1
Bryant, RE1

Reviews

6 reviews available for gentamicin and Tularemia

ArticleYear
Tularemia: epidemiology, diagnosis, and treatment.
    Pediatric annals, 2013, Volume: 42, Issue:7

    Topics: Anti-Bacterial Agents; Diagnosis, Differential; Gentamicins; Humans; Prognosis; Streptomycin; Syndro

2013
Tularemia: retrospective review of 10 years' experience in Arkansas.
    Clinical pediatrics, 2011, Volume: 50, Issue:1

    Topics: Adolescent; Anti-Bacterial Agents; Arkansas; Child; Child, Preschool; Diagnosis, Differential; Femal

2011
Pneumonic tularemia on Martha's Vineyard: clinical, epidemiologic, and ecological characteristics.
    Annals of the New York Academy of Sciences, 2007, Volume: 1105

    Topics: Animals; Anti-Bacterial Agents; Disease Reservoirs; Disease Vectors; Ecology; Francisella tularensis

2007
Relapse of tularemia after aminoglycoside therapy: case report and discussion of therapeutic options.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1995, Volume: 20, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Ciprofloxacin; Female; Gentamicins; Humans; Recurrence; Tularemia

1995
Streptomycin and alternative agents for the treatment of tularemia: review of the literature.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 19, Issue:1

    Topics: Francisella tularensis; Gentamicins; Humans; Microbial Sensitivity Tests; Streptomycin; Tetracycline

1994
Tularemia from a cat bite: case report and review of feline-associated tularemia.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1993, Volume: 16, Issue:4

    Topics: Animals; Bites and Stings; Cat Diseases; Cats; Clindamycin; Gentamicins; Humans; Male; Middle Aged;

1993

Trials

1 trial available for gentamicin and Tularemia

ArticleYear
Treatment failure of gentamicin in pediatric patients with oropharyngeal tularemia.
    Medical science monitor : international medical journal of experimental and clinical research, 2011, Volume: 17, Issue:7

    Topics: Adolescent; Child; Female; Gentamicins; Humans; Lymph Nodes; Male; Retrospective Studies; Streptomyc

2011

Other Studies

33 other studies available for gentamicin and Tularemia

ArticleYear
Tularemia in children during the last outbreak in Kosovo.
    Journal of infection in developing countries, 2022, 08-30, Volume: 16, Issue:8

    Topics: Adolescent; Adult; Child; Child, Preschool; Disease Outbreaks; Fever; Gentamicins; Humans; Kosovo; R

2022
Paediatric oropharyngeal tularaemia requiring surgical intervention.
    BMJ case reports, 2019, Sep-06, Volume: 12, Issue:9

    Topics: Abscess; Anti-Bacterial Agents; Child, Preschool; Drainage; Fever; Francisella tularensis; Gentamici

2019
Disseminated Tularemia: Finding the Needle in the Haystack.
    Journal of the Pediatric Infectious Diseases Society, 2021, Apr-03, Volume: 10, Issue:3

    Topics: Cytomegalovirus; Cytomegalovirus Infections; Gentamicins; Humans; Infant; Male; Tularemia

2021
Severe glandular tularemia in a patient treated with anti-tumour necrosis factor for psoriatic arthritis.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2017, Volume: 60

    Topics: Adalimumab; Adult; Animals; Anti-Bacterial Agents; Antibodies, Monoclonal; Antirheumatic Agents; Art

2017
Imaging Findings of Ulceroglandular Tularemia.
    Journal of radiology case reports, 2017, Volume: 11, Issue:1

    Topics: Anti-Bacterial Agents; Child; Combined Modality Therapy; Diagnosis, Differential; Gentamicins; Human

2017
Case Report: Atypical Cutaneous Manifestations of Tularemia after Horsefly Bite.
    The American journal of tropical medicine and hygiene, 2018, Volume: 98, Issue:6

    Topics: Amoxicillin-Potassium Clavulanate Combination; Animals; Anti-Bacterial Agents; Antibodies, Bacterial

2018
Unusual presentatıon of oropharyngeal tularemıa: a case report.
    Vector borne and zoonotic diseases (Larchmont, N.Y.), 2013, Volume: 13, Issue:5

    Topics: Administration, Intravenous; Animals; Anti-Bacterial Agents; Diagnosis, Differential; Fever; Francis

2013
[Fever and lymphadenopathy. Report of 4 cases of tularemia].
    Der Internist, 2013, Volume: 54, Issue:4

    Topics: Aged; Anti-Infective Agents; Child; Ciprofloxacin; Female; Fever; Gentamicins; Humans; Lymphatic Dis

2013
A case of oculoglandular tularemia resistant to medical treatment.
    Scandinavian journal of infectious diseases, 2013, Volume: 45, Issue:9

    Topics: Adolescent; Anti-Bacterial Agents; Eye Infections, Bacterial; Gentamicins; Humans; Lymph Nodes; Lymp

2013
Tularemia during pregnancy: three cases.
    Vector borne and zoonotic diseases (Larchmont, N.Y.), 2014, Volume: 14, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Female; Gentamicins; Humans; Infant; Live Birth; Pregnancy; Pregnancy

2014
Pilot error.
    The Journal of the Oklahoma State Medical Association, 2014, Volume: 107, Issue:11

    Topics: Anti-Bacterial Agents; Diagnosis, Differential; Gentamicins; Humans; Infectious Disease Medicine; Ok

2014
Epidemiological and clinical characteristics and management of oropharyngeal tularemia outbreak.
    Turkish journal of medical sciences, 2015, Volume: 45, Issue:4

    Topics: Adolescent; Adult; Animals; Anti-Bacterial Agents; Disease Management; Disease Outbreaks; Disease Ve

2015
Gallium Potentiates the Antibacterial Effect of Gentamicin against Francisella tularensis.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Bacterial Load; Biological Assay; Drug Synergism; Female; Ferrozine;

2016
Needle-Free Delivery of Acetalated Dextran-Encapsulated AR-12 Protects Mice from Francisella tularensis Lethal Challenge.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:4

    Topics: Acetals; Administration, Intranasal; Animals; Anti-Bacterial Agents; Bacterial Load; Dextrans; Drug

2016
[Streptococcus pneumonia infection and positive blood culture with Francisella tularensis, in a renal transplant recipient].
    Presse medicale (Paris, France : 1983), 2011, Volume: 40, Issue:12 Pt 1

    Topics: Aged; Anti-Bacterial Agents; Bacteriological Techniques; Blood; Ceftriaxone; Ciprofloxacin; Drug The

2011
Post-exposure immunization against Francisella tularensis membrane proteins augments protective efficacy of gentamicin in a mouse model of pneumonic tularemia.
    Vaccine, 2012, Jul-13, Volume: 30, Issue:33

    Topics: Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Load; Bacterial Vaccines; Disease

2012
Francisella tularensis subspecies holarctica, Tasmania, Australia, 2011.
    Emerging infectious diseases, 2012, Volume: 18, Issue:9

    Topics: Adult; Animals; Anti-Bacterial Agents; Australia; Bites and Stings; Female; Francisella tularensis;

2012
Tularemia in Delaware: forgotten but not gone.
    Delaware medical journal, 2003, Volume: 75, Issue:4

    Topics: Adolescent; Anti-Bacterial Agents; Delaware; Gentamicins; Humans; Male; Oxacillin; Penicillins; Tula

2003
Intranasal interleukin-12 treatment promotes antimicrobial clearance and survival in pulmonary Francisella tularensis subsp. novicida infection.
    Antimicrobial agents and chemotherapy, 2004, Volume: 48, Issue:12

    Topics: Adjuvants, Immunologic; Administration, Intranasal; Animals; Anti-Bacterial Agents; Female; Francise

2004
Tularemia and once-daily gentamicin.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Drug Administration Schedule; Gentamicins; Humans; Male; Tularemia

2006
Tularemia induced bilateral optic neuritis.
    The Journal of the Arkansas Medical Society, 2006, Volume: 102, Issue:9

    Topics: Adult; Doxycycline; Francisella tularensis; Gentamicins; Humans; Male; Optic Neuritis; Tularemia

2006
Medical image. Tularaemic cervical lymphadenopathy.
    The New Zealand medical journal, 2007, Jan-26, Volume: 120, Issue:1248

    Topics: Adult; Anti-Bacterial Agents; Gentamicins; Humans; Lymphatic Diseases; Male; Neck; Tularemia

2007
Two unusual glandular presentations of tick-borne tularemia.
    Medecine et maladies infectieuses, 2008, Volume: 38, Issue:3

    Topics: Animals; Bites and Stings; Ciprofloxacin; Combined Modality Therapy; Contraindications; Doxycycline;

2008
Tularemia and the tomcat.
    JAMA, 1981, Sep-18, Volume: 246, Issue:12

    Topics: Adult; Animals; Bites and Stings; Cat Diseases; Cats; Female; Gentamicins; Humans; Male; Pregnancy;

1981
Treatment of tularemia, including pulmonary tularemia, with gentamicin.
    The American review of respiratory disease, 1980, Volume: 121, Issue:1

    Topics: Aged; Animals; Evaluation Studies as Topic; Francisella tularensis; Gentamicins; Humans; Kanamycin;

1980
Treatment of tularemia with gentamicin in pediatric patients.
    The Pediatric infectious disease journal, 1995, Volume: 14, Issue:2

    Topics: Adolescent; Arkansas; Child; Child, Preschool; Female; Gentamicins; Humans; Infant; Male; Rural Popu

1995
Tularemia presenting with splenic nodules.
    The Pediatric infectious disease journal, 1994, Volume: 13, Issue:9

    Topics: Child, Preschool; Diagnosis, Differential; Gentamicins; Hematologic Tests; Humans; Male; Splenomegal

1994
Susceptibility pattern of Scandinavian Francisella tularensis isolates with regard to oral and parenteral antimicrobial agents.
    APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 1993, Volume: 101, Issue:1

    Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Chloramphenicol; Doxycycline; Francisella tula

1993
Tularemic meningitis.
    The Pediatric infectious disease journal, 1998, Volume: 17, Issue:5

    Topics: Anti-Bacterial Agents; Antibodies, Bacterial; Child, Preschool; Doxycycline; Female; Francisella tul

1998
Oculoglandular tularemia.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1999, Volume: 117, Issue:1

    Topics: Aged; Aged, 80 and over; Anterior Chamber; Antibodies, Bacterial; Biopsy; Conjunctiva; Conjunctiviti

1999
Case report. Tularemia presenting as unresponsive pneumonia: diagnosis and therapy with gentamicin.
    Journal of the Tennessee Medical Association, 1978, Volume: 71, Issue:3

    Topics: Diagnosis, Differential; Gentamicins; Humans; Male; Middle Aged; Pneumonia; Tularemia

1978
Typhoidal tularemia.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1990, Volume: 108, Issue:1

    Topics: Adult; Eye Infections, Bacterial; Fluorescein Angiography; Fundus Oculi; Gentamicins; Humans; Male;

1990
Tularemia treated successfully with gentamicin.
    The American review of respiratory disease, 1972, Volume: 106, Issue:2

    Topics: Aged; Gentamicins; Hemagglutination Tests; Humans; Male; Radiography; Tularemia

1972