Page last updated: 2024-10-27

gentamicin and Soft Tissue Infections

gentamicin has been researched along with Soft Tissue Infections in 16 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Soft Tissue Infections: Infections of non-skeletal tissue, i.e., exclusive of bone, ligaments, cartilage, and fibrous tissue. The concept is usually referred to as skin and soft tissue infections and usually subcutaneous and muscle tissue are involved. The predisposing factors in anaerobic infections are trauma, ischemia, and surgery. The organisms often derive from the fecal or oral flora, particularly in wounds associated with intestinal surgery, decubitus ulcer, and human bites. (From Cecil Textbook of Medicine, 19th ed, p1688)

Research Excerpts

ExcerptRelevanceReference
" The aim of this study was to evaluate the bactericidal activity of AP-CECT7121, alone and with gentamicin, against multi-resistant bacteria isolated from human and animals with soft tissue infections."3.85Bactericidal Activity and Synergy Studies of Peptide AP-CECT7121 Against Multi-resistant Bacteria Isolated from Human and Animal Soft Tissue Infections. ( Bistoletti, M; Bruni, SS; Ceci, M; Delpech, G; Lissarrague, S; Sparo, M, 2017)
"To report a case of progressive necrotizing fasciitis of the face following acute dacryocystitis."1.32Facial necrotizing fasciitis following acute dacryocystitis. ( Lin, HC; Lin, PW, 2003)
"Only two relapse were seen, which had to be re-opened."1.30[Is primary would closure in septic pediatric surgery contraindicated?]. ( Beiler, HA; Benz, G; Daum, R; Schäfer, K, 1997)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (43.75)18.2507
2000's3 (18.75)29.6817
2010's6 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Delpech, G1
Bistoletti, M1
Ceci, M1
Lissarrague, S1
Bruni, SS1
Sparo, M1
Chen, PL1
Wu, CJ1
Chen, CS1
Tsai, PJ1
Tang, HJ1
Ko, WC1
Benito-González, F1
Benito, J1
Sánchez, LA1
Estevez Alonso, S1
Muñoz Herrera, A1
Batuecas-Caletrio, A1
Buchanan, R1
Stoesser, N1
Crook, D1
Bowler, IC1
Price, BL1
Lovering, AM1
Bowling, FL1
Dobson, CB1
Cavanaugh, DL1
Berry, J1
Yarboro, SR1
Dahners, LE1
Lin, PW1
Lin, HC1
Kilani, B1
Ammari, L1
Benaïssa, HT1
Ben Chaabane, T1
Fendri, C1
Grayson, LS1
Hansbrough, JF1
Zapata-Sirvent, R1
Roehrborn, AJ1
Kim, T1
Kim, S1
Mladenović, D1
Jovevski, S1
Schmidt, J1
Hackenbroch, MH1
Kumm, D1
Taravati, V1
Stemberger, A1
Grimm, H1
Bader, F1
Rahn, HD1
Ascherl, R1
Harving, S1
Hougaard, K1
Gottrup, F1
Kolmos, HJ1
Schäfer, K1
Beiler, HA1
Benz, G1
Daum, R1
Swanston, WH1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Randomized Control Trial of Vancomycin Powder Following Posterior Instrumented Spinal Surgery for Trauma[NCT01977989]Phase 4140 participants (Anticipated)Interventional2013-10-31Enrolling by invitation
Comparative Effectiveness and Cost-Benefit Analysis of Vancomycin Powder in High Risk Spine Surgery Patients[NCT01566422]0 participants (Actual)Interventional2012-06-30Withdrawn (stopped due to unable to enroll any participants)
Use of Collatamp G Antibiotic Impregnated Sponges in the Treatment of Peri-prosthetic Total Joint Infections[NCT01667874]Phase 317 participants (Actual)Interventional2013-01-31Terminated (stopped due to Difficulty in recruiting patients for the study)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for gentamicin and Soft Tissue Infections

ArticleYear
Is instillation drainage for the treatment of infected joints, bones and soft tissues still up to date?
    Archives of orthopaedic and trauma surgery, 1996, Volume: 115, Issue:3-4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthritis, Infectious; Child; Chi

1996
Local treatment of bone and soft tissue infections with the collagen-gentamicin sponge.
    The European journal of surgery. Supplement. : = Acta chirurgica. Supplement, 1997, Issue:578

    Topics: Animals; Anti-Bacterial Agents; Collagen; Controlled Clinical Trials as Topic; Disease Models, Anima

1997
[Gentacoll. A combined collagen-gentamicin preparation].
    Ugeskrift for laeger, 1997, Jul-07, Volume: 159, Issue:28

    Topics: Collagen; Drug Combinations; Drug Implants; Gentamicins; Humans; Osteomyelitis; Soft Tissue Infectio

1997

Other Studies

13 other studies available for gentamicin and Soft Tissue Infections

ArticleYear
Bactericidal Activity and Synergy Studies of Peptide AP-CECT7121 Against Multi-resistant Bacteria Isolated from Human and Animal Soft Tissue Infections.
    Probiotics and antimicrobial proteins, 2017, Volume: 9, Issue:3

    Topics: Adult; Animals; Anti-Bacterial Agents; Argentina; Cattle; Drug Resistance, Multiple, Bacterial; Drug

2017
Methicillin resistant Staphylococcus aureus (MRSA) in India: prevalence & susceptibility pattern.
    The Indian journal of medical research, 2013, Volume: 137, Issue:2

    Topics: Ciprofloxacin; Cross Infection; Erythromycin; Gentamicins; Humans; India; Methicillin; Methicillin-R

2013
A comparative study of clinical Aeromonas dhakensis and Aeromonas hydrophila isolates in southern Taiwan: A. dhakensis is more predominant and virulent.
    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases, 2014, Volume: 20, Issue:7

    Topics: Adult; Aeromonas; Aged; Animals; Anti-Bacterial Agents; Biofilms; Caenorhabditis elegans; Ceftriaxon

2014
Use of a gentamicin-impregnated collagen sheet (Collatamp(®)) in the management of major soft tissue complications in pediatric cochlear implants.
    Cochlear implants international, 2014, Volume: 15, Issue:5

    Topics: Anti-Bacterial Agents; Child, Preschool; Cochlear Implantation; Cochlear Implants; Collagen; Female;

2014
Multidrug-resistant Escherichia coli soft tissue infection investigated with bacterial whole genome sequencing.
    BMJ case reports, 2014, Oct-19, Volume: 2014

    Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; D

2014
Development of a Novel Collagen Wound Model To Simulate the Activity and Distribution of Antimicrobials in Soft Tissue during Diabetic Foot Infection.
    Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:11

    Topics: Anti-Bacterial Agents; Biofilms; Calcium Sulfate; Collagen; Diabetic Foot; Drug Resistance, Multiple

2016
Better prophylaxis against surgical site infection with local as well as systemic antibiotics. An in vivo study.
    The Journal of bone and joint surgery. American volume, 2009, Volume: 91, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Antibiotic Prophylaxis; Cefazolin; Dis

2009
Better prophylaxis against surgical site infection with local as well as systemic antibiotics. An in vivo study.
    The Journal of bone and joint surgery. American volume, 2009, Volume: 91, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Antibiotic Prophylaxis; Cefazolin; Dis

2009
Better prophylaxis against surgical site infection with local as well as systemic antibiotics. An in vivo study.
    The Journal of bone and joint surgery. American volume, 2009, Volume: 91, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Antibiotic Prophylaxis; Cefazolin; Dis

2009
Better prophylaxis against surgical site infection with local as well as systemic antibiotics. An in vivo study.
    The Journal of bone and joint surgery. American volume, 2009, Volume: 91, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Antibiotic Prophylaxis; Cefazolin; Dis

2009
Facial necrotizing fasciitis following acute dacryocystitis.
    American journal of ophthalmology, 2003, Volume: 136, Issue:1

    Topics: Abscess; Acute Disease; Combined Modality Therapy; Dacryocystitis; Debridement; Drug Therapy, Combin

2003
Escherichia vulneris as a cause of bacteremia in a patient with chronic lymphocytic leukemia.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2008, Volume: 12, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Bacteremia; Ciprofloxacin; Drug Therapy, Combination; Enterobacteriacea

2008
Soft tissue infection prophylaxis with gentamicin encapsulated in multivesicular liposomes: results from a prospective, randomized trial.
    Critical care medicine, 1995, Volume: 23, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Drug Carriers; Female; Gentamicins; Lipid Bilayers; Lipos

1995
[Gentamycin-polymethylmethacrylate in the treatment of osteoarticular panaritium].
    Acta chirurgica Iugoslavica, 1991, Volume: 38, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Female; Finger Joint; Gentamicins; Humans; Male; Methylmethacrylate; M

1991
[Is primary would closure in septic pediatric surgery contraindicated?].
    Langenbecks Archiv fur Chirurgie. Supplement. Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress, 1997, Volume: 114

    Topics: Abscess; Bacterial Infections; Child; Child, Preschool; Combined Modality Therapy; Contraindications

1997
Methicillin resistant Staphylococcus aureus.
    The West Indian medical journal, 1999, Volume: 48, Issue:1

    Topics: Anti-Bacterial Agents; Cause of Death; Cross Infection; Drug Resistance, Microbial; Drug Therapy, Co

1999