Page last updated: 2024-10-27

gentamicin and Sinus Infections

gentamicin has been researched along with Sinus Infections in 18 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Research Excerpts

ExcerptRelevanceReference
"To compare efficacy and outcome of daily saline irrigation versus saline/gentamicin for treating chronic rhinosinusitis (CRS)."5.15Safety and efficacy of once-daily nasal irrigation for the treatment of pediatric chronic rhinosinusitis. ( He, J; Johnson, P; Mayo, MS; Sykes, KJ; Wei, JL, 2011)
"Eighteen mild-to-moderate asthmatics with CRS were subjected to antral sinoscopy and endosinusal treatment with 2 mg of dexamethasone and 40 mg of gentamicin per maxillary sinus for 7 days."3.72Effect of endosinusal treatment on cellular markers in mild and moderate asthmatics. ( Baudoin, T; Kalogjera, L; Vagić, D, 2003)
" Although the use of steroids as adjunctive therapy for bacterial meningitis has been found to be beneficial, the dosage of dexamethasone administered in our cases may not be enough to suppress the synthesis and release of the cytokines."1.29[Two cases of severe bacterial meningitis with paranasal sinusitis followed by cerebrovascular disease--pathophysiology and treatment of cerebrovascular disease]. ( Matsukura, S; Miyazato, M; Nagata, N; Ohi, T; Sugimoto, S, 1996)
"The acute frontal sinusitis is the most frequent cause."1.29[Intracranial and cranial complications of paranasal sinusitis. Report of 4 cases at the Lomé University Hospital Center]. ( Kpemissi, E; Mathias, A; Sossou, K, 1995)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19909 (50.00)18.7374
1990's3 (16.67)18.2507
2000's2 (11.11)29.6817
2010's3 (16.67)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Kisiel, M1
Sjölander, I1
Klar, A1
Asplund Stenkvist, M1
Laurell, G1
Moghadam, SJ1
Navarro, L1
Leclerc, L1
Hodin, S1
Pourchez, J1
Thomas, J1
Fayad, M1
Tong, D1
Richards, BF1
Wong, KK1
Marglani, O1
Westerberg, BD1
Javer, AR1
Wei, JL1
Sykes, KJ1
Johnson, P1
He, J1
Mayo, MS1
Kalogjera, L1
Vagić, D1
Baudoin, T1
Miyazato, M1
Ohi, T1
Sugimoto, S1
Nagata, N1
Matsukura, S1
Poliakova, TS1
Luchikhin, LA1
Goncharova, MV1
Shubin, MN1
Kpemissi, E1
Mathias, A1
Sossou, K1
Schindler, K1
Cikrit, W1
Steigenberger, H1
Badré, R1
Guillerm, R1
Mouel, C1
Poiret, F1
Wagner, WH1
Knöringer, P1
Sambe, B1
Murakami, H1
Kobayasi, K1
Jo, K1
Inafuku, S1
McCracken, GH1
Eichenwald, HF1
Crozier, DN1
Fior, R1
Gregorius, FK1
Rich, JR1
Itabashi, HH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison of Post op Outcomes in Endoscopic Sinus Surgery Using Varying Nasal Sinus Irrigations. Saline vs. Saline and Budesonide vs Saline, Budesonide, and Culture Directed Topical Antibiotics[NCT03303677]Phase 30 participants (Actual)Interventional2018-04-01Withdrawn (stopped due to Withdrawn by sponsor)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for gentamicin and Sinus Infections

ArticleYear
Antimicrobiol therapy: therapeutic recommendations and a review of newer drugs. Part I. Therapy of infectious conditions.
    The Journal of pediatrics, 1974, Volume: 85, Issue:3

    Topics: Adolescent; Ampicillin; Anti-Bacterial Agents; Arthritis, Infectious; Bacteroides Infections; Brain

1974
Cystic fibrosis: a not-so-fatal disease.
    Pediatric clinics of North America, 1974, Volume: 21, Issue:4

    Topics: Adolescent; Adult; Child; Child, Preschool; Cystic Fibrosis; Diet Therapy; Dietary Fats; Drug Therap

1974

Trials

1 trial available for gentamicin and Sinus Infections

ArticleYear
Safety and efficacy of once-daily nasal irrigation for the treatment of pediatric chronic rhinosinusitis.
    The Laryngoscope, 2011, Volume: 121, Issue:9

    Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Chronic Disease; Double-Blind Method; Fe

2011

Other Studies

15 other studies available for gentamicin and Sinus Infections

ArticleYear
Development of bacterial resistance during treatment with topical gentamicin for chronic rhinosinusitis in patients with cystic fibrosis and primary ciliary dyskinesis. Retrospective case series.
    Otolaryngologia polska = The Polish otolaryngology, 2020, Jan-28, Volume: 74, Issue:3

    Topics: Adult; Aged; Anti-Bacterial Agents; Ciliary Motility Disorders; Cystic Fibrosis; Drug Resistance, Mi

2020
Toward smart Nebulization: Engineering acoustic airflow to penetrate maxillary sinuses in chronic rhinosinusitis.
    International journal of pharmaceutics, 2018, Jul-30, Volume: 546, Issue:1-2

    Topics: Acoustics; Administration, Intranasal; Anti-Bacterial Agents; Chronic Disease; Gentamicins; Humans;

2018
Use of ventriculostomy in the treatment of septic cavernous sinus thrombosis (SCST).
    BMJ case reports, 2019, Apr-23, Volume: 12, Issue:4

    Topics: Administration, Intravenous; Aftercare; Aged; Angiography; Anti-Bacterial Agents; Cavernous Sinus; C

2019
Systemic absorption of topical gentamicin sinus irrigation.
    Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale, 2008, Volume: 37, Issue:3

    Topics: Absorption; Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Chronic

2008
Effect of endosinusal treatment on cellular markers in mild and moderate asthmatics.
    Acta oto-laryngologica, 2003, Volume: 123, Issue:2

    Topics: Administration, Topical; Adolescent; Adult; Asthma; Blood Proteins; Dexamethasone; Eosinophil Granul

2003
[Two cases of severe bacterial meningitis with paranasal sinusitis followed by cerebrovascular disease--pathophysiology and treatment of cerebrovascular disease].
    Rinsho shinkeigaku = Clinical neurology, 1996, Volume: 36, Issue:9

    Topics: Adult; Ampicillin; Anti-Bacterial Agents; Cerebrovascular Disorders; Dexamethasone; Drug Therapy, Co

1996
[Ligenten treatment of sinusitis].
    Vestnik otorinolaringologii, 1997, Issue:2

    Topics: Administration, Topical; Adult; Anti-Infective Agents; Drug Combinations; Female; Gels; Gentamicins;

1997
[Intracranial and cranial complications of paranasal sinusitis. Report of 4 cases at the Lomé University Hospital Center].
    Dakar medical, 1995, Volume: 40, Issue:2

    Topics: Abscess; Adolescent; Ampicillin; Child; Combined Modality Therapy; Cutaneous Fistula; Drainage; Drug

1995
[The effect of various antibiotics on the mixed flora of the maxillary sinus in sinusitis(author's transl)].
    Laryngologie, Rhinologie, Otologie, 1975, Volume: 54, Issue:1

    Topics: Administration, Topical; Ampicillin; Anti-Bacterial Agents; Bacteria; Doxycycline; Gentamicins; Huma

1975
[Experimental results and use of the manosonic aerosoliser (U.D.V.) for the treatment of middle-ear and affections (author's transl)].
    Laryngologie, Rhinologie, Otologie, 1978, Volume: 57, Issue:7

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Evaluation Studies as Topic; Female; Gentamicins;

1978
[Special problems in the chemotherapy of bacterial infections in otolaryngology (author's transl)].
    HNO, 1977, Volume: 25, Issue:11

    Topics: Aminoglycosides; Bacterial Infections; Ear; Gentamicins; Humans; Kanamycin; Neomycin; Otitis Media;

1977
[Treatment of bone infection in the area of the skull].
    Unfallchirurgie, 1986, Volume: 12, Issue:2

    Topics: Brain Abscess; Combined Modality Therapy; Debridement; Follow-Up Studies; Fractures, Spontaneous; Ge

1986
[Treatment of otorhinolaryngological infections with BB-K8 (author's transl)].
    The Japanese journal of antibiotics, 1974, Volume: 27, Issue:3

    Topics: Acute Disease; Adult; Child; Child, Preschool; Female; Gentamicins; Humans; Infant; Kanamycin; Male;

1974
[Aerosol therapy of mucopurulent rhinosinusitis with gentamicin. Clinical observations on 131 cases].
    La Clinica terapeutica, 1972, Jun-30, Volume: 61, Issue:6

    Topics: Adolescent; Aerosols; Child; Child, Preschool; Ethmoid Sinus; Gentamicins; Humans; Maxillary Sinus;

1972
Subdural empyema. Recent experience in diagnosis and treatment.
    Bulletin of the Los Angeles neurological societies, 1974, Volume: 39, Issue:3

    Topics: Adolescent; Autopsy; Brain Diseases; Cerebral Cortex; Cerebral Hemorrhage; Cerebral Ventricles; Dexa

1974