gentamicin has been researched along with Rupture, Spontaneous in 17 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Rupture, Spontaneous: Tear or break of an organ, vessel or other soft part of the body, occurring in the absence of external force.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This prospective, randomized, double-blind study compares the efficacy, safety and cost-effectiveness of ampicillin, gentamicin and clindamycin (AGC) or cefotaxime and clindamycin (CC) for the treatment of children with complicated appendicitis." | 9.07 | A randomized clinical trial of ampicillin, gentamicin and clindamycin versus cefotaxime and clindamycin in children with ruptured appendicitis. ( Golladay, ES; Kaplan, S; King, DR; Mason, EO; Mollitt, DL; Pokorny, W; Schropp, KP; Wise, WE, 1991) |
| "A randomized, double-blinded, controlled clinical study of 84 patients with surgically treated gangrenous or perforated appendicitis was done to compare the efficacy of the combination of aztreonam, the first monobactam antibiotic, with gentamicin when either was combined with clindamycin." | 9.06 | Surgically treated gangrenous or perforated appendicitis. A comparison of aztreonam and clindamycin versus gentamicin and clindamycin. ( Appleman, MD; Berne, TV; Chenella, FC; Gill, MA; Heseltine, PN; Yellin, AE, 1987) |
| "A matched case-control study of the efficacy of gentamicin dosage adjustment through the use of pharmacokinetic analysis of serum drug concentrations in patients treated by appendectomy for perforated or gangrenous appendicitis was performed." | 7.67 | Matched case-control study of adjusted versus nonadjusted gentamicin dosing in perforated and gangrenous appendicitis. ( Appleman, MD; Berne, TV; Cheetham, TC; Chenella, FC; Gill, MA; Heseltine, PN; Yellin, AE, 1986) |
| "This prospective, randomized, double-blind study compares the efficacy, safety and cost-effectiveness of ampicillin, gentamicin and clindamycin (AGC) or cefotaxime and clindamycin (CC) for the treatment of children with complicated appendicitis." | 5.07 | A randomized clinical trial of ampicillin, gentamicin and clindamycin versus cefotaxime and clindamycin in children with ruptured appendicitis. ( Golladay, ES; Kaplan, S; King, DR; Mason, EO; Mollitt, DL; Pokorny, W; Schropp, KP; Wise, WE, 1991) |
| "A randomized, double-blinded, controlled clinical study of 84 patients with surgically treated gangrenous or perforated appendicitis was done to compare the efficacy of the combination of aztreonam, the first monobactam antibiotic, with gentamicin when either was combined with clindamycin." | 5.06 | Surgically treated gangrenous or perforated appendicitis. A comparison of aztreonam and clindamycin versus gentamicin and clindamycin. ( Appleman, MD; Berne, TV; Chenella, FC; Gill, MA; Heseltine, PN; Yellin, AE, 1987) |
| "A matched case-control study of the efficacy of gentamicin dosage adjustment through the use of pharmacokinetic analysis of serum drug concentrations in patients treated by appendectomy for perforated or gangrenous appendicitis was performed." | 3.67 | Matched case-control study of adjusted versus nonadjusted gentamicin dosing in perforated and gangrenous appendicitis. ( Appleman, MD; Berne, TV; Cheetham, TC; Chenella, FC; Gill, MA; Heseltine, PN; Yellin, AE, 1986) |
| "The relationships between resistant pathogens, serum levels of gentamicin, and the outcomes of gangrenous or perforated appendicitis were analyzed in 147 patients." | 3.66 | Perforated and gangrenous appendicitis: an analysis of antibiotic failures. ( Appleman, MD; Berne, TV; Chenella, FC; Gill, MA; Heseltine, PN; Kern, JW; Yellin, AE, 1983) |
| "Surgical wound infections were significantly reduced by the collagen-gentamicin implant." | 2.69 | Effectiveness of collagen-gentamicin implant for treatment of "dirty" abdominal wounds. ( Delgado, FJ; Guerrero, TS; Guzmán Valdivia Gomez, G; Lluck, MC, 1999) |
| "Cefepime is a new extended-spectrum cephalosporin with gram-positive and gram-negative coverage including Staphylococcus aureus and Pseudomonas aeruginosa." | 2.67 | Analysis of cefepime tissue penetration into human appendix. ( Appleman, MD; Berne, TV; Chin, A; Gill, MA; Heseltine, PN; Knupp, CA; Okamoto, MP; Sclar, DA; Yellin, AE, 1991) |
| "The mortality of patients with brain abscesses has decreased significantly from 38% in the 1950s to 25% in the 1980s (P = 0." | 2.39 | Intraventricular rupture of a purulent brain abscess: case report. ( Geisler, FH; Olivi, A; Zeidman, SM, 1995) |
| "Rupture of a mycotic aneurysm often occurs before the diagnosis of bacterial endocarditis is made or whilst the patient is being treated with antibiotics." | 1.27 | Late rupture of a mycotic aneurysm after "cure" of bacterial endocarditis. ( Bamford, J; Hodges, J; Warlow, C, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (52.94) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Velez, MC | 1 |
| Athale, UH | 1 |
| Loe, W | 1 |
| Warrier, RP | 1 |
| Nubile, M | 1 |
| Carpineto, P | 1 |
| Lanzini, M | 1 |
| Ciancaglini, M | 1 |
| Zuppardi, E | 1 |
| Mastropasqua, L | 1 |
| Heseltine, PN | 8 |
| Yellin, AE | 8 |
| Appleman, MD | 8 |
| Gill, MA | 7 |
| Chenella, FC | 6 |
| Kern, JW | 1 |
| Berne, TV | 8 |
| Abdel-Lah, BA | 1 |
| Fernández Alvarez, D | 1 |
| Lozano Sánchez, F | 1 |
| Alvarez Aparicio, E | 1 |
| Gómez Alonso, A | 1 |
| Salazar A-Villalobos, V | 1 |
| Philben, V | 1 |
| Krantz, BE | 1 |
| Zeidman, SM | 1 |
| Geisler, FH | 1 |
| Olivi, A | 1 |
| Gill, M | 1 |
| Chin, A | 2 |
| Baker, FJ | 1 |
| Guzmán Valdivia Gomez, G | 1 |
| Guerrero, TS | 1 |
| Lluck, MC | 1 |
| Delgado, FJ | 1 |
| Rice, HE | 1 |
| Brown, RL | 1 |
| Gollin, G | 1 |
| Caty, MG | 1 |
| Gilbert, J | 1 |
| Skinner, MA | 1 |
| Glick, PL | 1 |
| Azizkhan, RG | 1 |
| Okamoto, MP | 1 |
| Knupp, CA | 1 |
| Sclar, DA | 1 |
| Schropp, KP | 1 |
| Kaplan, S | 1 |
| Golladay, ES | 1 |
| King, DR | 1 |
| Pokorny, W | 1 |
| Mollitt, DL | 1 |
| Wise, WE | 1 |
| Mason, EO | 1 |
| Riggio, CE | 1 |
| Leedom, JM | 1 |
| Bamford, J | 1 |
| Hodges, J | 1 |
| Warlow, C | 1 |
| Cheetham, TC | 1 |
| Feldman, MJ | 1 |
| Sharon, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Collagen-Gentamicin Implant in the Treatment of Contaminated Surgical Abdominal Wounds - A Randomized Controlled Trial[NCT00977405] | Phase 2 | 70 participants (Anticipated) | Interventional | 2009-09-30 | Terminated | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for gentamicin and Rupture, Spontaneous
| Article | Year |
|---|---|
Intraventricular rupture of a purulent brain abscess: case report.
Topics: Brain Abscess; Cerebral Ventricles; Combined Modality Therapy; Craniotomy; Gentamicins; Humans; Male | 1995 |
9 trials available for gentamicin and Rupture, Spontaneous
| Article | Year |
|---|---|
[Logical use of prophylactic antibacterial agents in infectious post-appendectomy complications. A controlled clinical trial].
Topics: Appendectomy; Appendicitis; Bacterial Infections; Child; Clindamycin; Clinical Trials as Topic; Fema | 1982 |
Prospective randomized study of two different doses of clindamycin admixed with gentamicin in the management of perforated appendicitis.
Topics: Adult; Appendicitis; Bacterial Infections; Clindamycin; Drug Administration Schedule; Drug Therapy, | 1993 |
Effectiveness of collagen-gentamicin implant for treatment of "dirty" abdominal wounds.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local; | 1999 |
Results of a pilot trial comparing prolonged intravenous antibiotics with sequential intravenous/oral antibiotics for children with perforated appendicitis.
Topics: Administration, Oral; Adolescent; Ampicillin; Appendicitis; Child; Child, Preschool; Clavulanic Acid | 2001 |
Analysis of cefepime tissue penetration into human appendix.
Topics: Adolescent; Adult; Appendectomy; Appendicitis; Appendix; Ascitic Fluid; Cefepime; Cephalosporins; Cl | 1991 |
A randomized clinical trial of ampicillin, gentamicin and clindamycin versus cefotaxime and clindamycin in children with ruptured appendicitis.
Topics: Adolescent; Ampicillin; Appendicitis; Cefotaxime; Child; Child, Preschool; Clindamycin; Combined Mod | 1991 |
The role of Pseudomonas species in patients treated with ampicillin and Sulbactam for gangrenous and perforated appendicitis.
Topics: Adult; Ampicillin; Appendicitis; Clindamycin; Double-Blind Method; Drug Therapy, Combination; Female | 1985 |
Surgically treated gangrenous or perforated appendicitis. A comparison of aztreonam and clindamycin versus gentamicin and clindamycin.
Topics: Adult; Appendicitis; Aztreonam; Clindamycin; Clinical Trials as Topic; Double-Blind Method; Drug The | 1987 |
Cost analysis of antibiotics in the management of perforated or gangrenous appendicitis.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Appendicitis; Cefamandole; Cefoperazone; Clindamycin; Cost | 1986 |
7 other studies available for gentamicin and Rupture, Spontaneous
| Article | Year |
|---|---|
Acute perforative appendicitis during preoperative chemotherapy for Wilms tumor.
Topics: Abdominal Pain; Acute Disease; Antineoplastic Combined Chemotherapy Protocols; Appendicitis; Ceftazi | 2003 |
Multilayer amniotic membrane transplantation for bacterial keratitis with corneal perforation after hyperopic photorefractive keratectomy: case report and literature review.
Topics: Amnion; Anti-Bacterial Agents; Combined Modality Therapy; Corneal Ulcer; Eye Infections, Bacterial; | 2007 |
Perforated and gangrenous appendicitis: an analysis of antibiotic failures.
Topics: Anti-Bacterial Agents; Appendicitis; Bacteroides fragilis; Bacteroides Infections; Cefamandole; Cefo | 1983 |
Nontraumatic perforation of the common bile duct.
Topics: Adult; Aged; Bile Duct Diseases; Cholangitis; Cystic Duct; Gentamicins; Humans; Rupture, Spontaneous | 1981 |
Imipenem therapy for perforated and gangrenous appendicitis.
Topics: Adult; Aged; Appendectomy; Appendicitis; Ascitic Fluid; Cilastatin; Clindamycin; Cyclopropanes; Drug | 1986 |
Late rupture of a mycotic aneurysm after "cure" of bacterial endocarditis.
Topics: Aneurysm, Infected; Cerebral Angiography; Cerebral Hemorrhage; Drug Therapy, Combination; Endocardit | 1986 |
Matched case-control study of adjusted versus nonadjusted gentamicin dosing in perforated and gangrenous appendicitis.
Topics: Adult; Appendicitis; Dose-Response Relationship, Drug; Female; Gangrene; Gentamicins; Humans; Intest | 1986 |