Page last updated: 2024-10-27

gentamicin and Retinal Diseases

gentamicin has been researched along with Retinal Diseases in 17 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Retinal Diseases: Diseases involving the RETINA.

Research Excerpts

ExcerptRelevanceReference
"We encountered two cases of macular infarction that occurred after vitrectomy performed for mild endophthalmitis, which, on culture, yielded Staphylococcus epidermidis."5.27Macular infarction after endophthalmitis treated with vitrectomy and intravitreal gentamicin. ( Campochiaro, PA; Conway, BP, 1986)
"Light and electron microscopy of gentamicin-treated eyes showed inner-retinal edema and disruption of the nerve-fiber and ganglion-cell layers within the more dependent retina vs sparing of the less dependent half of the retina."3.69The role of gravity in gentamicin-induced toxic effects in a rabbit model. ( Anderson, CT; Buggage, RR; Grossniklaus, HE; Hutchinson, A; Lim, JI, 1994)
" It emphasizes that less toxic subconjuctival antibiotics may be considered for sutureless surgery, since if aminoglycoside toxicity occurs, the patient's vision may be permanently affected."1.39Gentamicin-induced macular toxicity in 25-gauge sutureless vitrectomy. ( Brouzas, D; Davou, S; Georgalas, I; Koutsandrea, C; Moschos, MM, 2013)
"Ocular pigmentation partially protects the rabbit retina from the toxic action of gentamicin."1.29Ocular pigmentation protects the rabbit retina from gentamicin-induced toxicity. ( Lazar, M; Lei, B; Loewenstein, A; Perlman, I; Zemel, E, 1995)
" A survey of retinal specialists has suggested that amikacin or low-dose gentamicin can also cause macular toxic side effects."1.29Aminoglycoside toxicity in the treatment of endophthalmitis. The Aminoglycoside Toxicity Study Group. ( Campochiaro, PA; Lim, JI, 1994)
"To study the toxic effect of aminoglycoside antibiotics in the primate retina, gentamicin sulfate was injected into the center of the vitreous cavity of Cebus navrigatus monkeys."1.28Gentamicin toxicity in the primate retina. ( Campochiaro, PA; Conway, BP; D'Amico, DJ; Hanninen, LA; Kenyon, KR; Tabatabay, CA, 1989)
"We encountered two cases of macular infarction that occurred after vitrectomy performed for mild endophthalmitis, which, on culture, yielded Staphylococcus epidermidis."1.27Macular infarction after endophthalmitis treated with vitrectomy and intravitreal gentamicin. ( Campochiaro, PA; Conway, BP, 1986)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19904 (23.53)18.7374
1990's9 (52.94)18.2507
2000's1 (5.88)29.6817
2010's3 (17.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Behera, UC1
Singh, A1
Jain, L1
Desai, A1
Heath Jeffery, RC1
Bowden, FJ1
Essex, RW1
Brouzas, D1
Moschos, MM1
Koutsandrea, C1
Davou, S1
Georgalas, I1
Holak, H1
Becker, R1
Holak, S1
D'Amico, DJ2
Libert, J1
Kenyon, KR2
Hanninen, LA2
Caspers-Velu, L1
Kanter, ED1
Brucker, AJ1
Daily, MJ1
Kachmaryk, MM1
Foody, RJ1
Zemel, E1
Loewenstein, A1
Lei, B1
Lazar, M1
Perlman, I1
Grizzard, WS1
Lim, JI2
Anderson, CT1
Hutchinson, A1
Buggage, RR1
Grossniklaus, HE1
De Maio, R1
Oliver, GL1
Chu, TG1
Ferreira, M1
Ober, RR1
Campochiaro, PA3
Rosenbaum, JD1
Krumholz, DM1
Metz, DM1
Conway, BP2
Tabatabay, CA1
Schatz, H1
McDonald, HR1

Other Studies

17 other studies available for gentamicin and Retinal Diseases

ArticleYear
Serial Swept-Source Optical Coherence Tomography Features of Gentamicin Macular Toxicity: A Glimpse Into the Injury Cascade.
    Ophthalmic surgery, lasers & imaging retina, 2018, 06-01, Volume: 49, Issue:6

    Topics: Adult; Anti-Bacterial Agents; Gentamicins; Humans; Injections, Intraocular; Ischemia; Macula Lutea;

2018
Subconjunctival gentamicin-induced macular toxicity following sutureless 25-gauge vitrectomy.
    Clinical & experimental ophthalmology, 2017, Volume: 45, Issue:3

    Topics: Aged; Anti-Bacterial Agents; Conjunctiva; Cryotherapy; Endotamponade; Eye Infections, Bacterial; Gen

2017
Gentamicin-induced macular toxicity in 25-gauge sutureless vitrectomy.
    Cutaneous and ocular toxicology, 2013, Volume: 32, Issue:3

    Topics: Anti-Bacterial Agents; Gentamicins; Humans; Injections; Male; Middle Aged; Retinal Diseases; Vitrect

2013
[Long-term follow-up of bilateral endogenous Klebsiella endophthalmitis].
    Klinische Monatsblatter fur Augenheilkunde, 2003, Volume: 220, Issue:5

    Topics: Abscess; Aged; Cefotaxime; Cefuroxime; Drug Therapy, Combination; Endophthalmitis; Follow-Up Studies

2003
Retinal toxicity of intravitreal gentamicin. An electron microscopic study.
    Investigative ophthalmology & visual science, 1984, Volume: 25, Issue:5

    Topics: Animals; Gentamicins; Lysosomes; Microscopy, Electron; Necrosis; Pigment Epithelium of Eye; Rabbits;

1984
Aminoglycoside macular infarction in association with gentamicin-soaked collagen corneal shield.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1995, Volume: 113, Issue:11

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Collagen; Drug Delivery Systems; Fluorescein Angiogr

1995
Successful prevention of visual loss with emergency management following inadvertent intracameral injection of gentamicin.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1995, Volume: 113, Issue:7

    Topics: Anterior Chamber; Cataract Extraction; Female; Fluorescein Angiography; Fundus Oculi; Gentamicins; H

1995
Ocular pigmentation protects the rabbit retina from gentamicin-induced toxicity.
    Investigative ophthalmology & visual science, 1995, Volume: 36, Issue:9

    Topics: Albinism; Animals; Electroretinography; Gentamicins; Injections; Melanins; Pigmentation; Rabbits; Re

1995
Aminoglycoside toxicity in the treatment of endophthalmitis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1995, Volume: 113, Issue:3

    Topics: Amikacin; Endophthalmitis; Gentamicins; Humans; Ischemia; Ophthalmic Solutions; Retinal Diseases; Re

1995
The role of gravity in gentamicin-induced toxic effects in a rabbit model.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1994, Volume: 112, Issue:10

    Topics: Animals; Edema; Gentamicins; Gravitation; Injections; Nerve Fibers; Rabbits; Retina; Retinal Disease

1994
Recovery of useful vision after presumed retinal and choroidal toxic effects from gentamicin administration.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1994, Volume: 112, Issue:6

    Topics: Aged; Cataract Extraction; Choroid Diseases; Female; Gentamicins; Humans; Lenses, Intraocular; Retin

1994
Immediate pars plana vitrectomy in the management of inadvertent intracameral injection of gentamicin. A rabbit experimental model.
    Retina (Philadelphia, Pa.), 1994, Volume: 14, Issue:1

    Topics: Animals; Anterior Chamber; Cataract Extraction; Disease Models, Animal; Gentamicins; Injections; Len

1994
Aminoglycoside toxicity in the treatment of endophthalmitis. The Aminoglycoside Toxicity Study Group.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1994, Volume: 112, Issue:1

    Topics: Aged; Amikacin; Bacteria; Endophthalmitis; Eye Infections, Bacterial; Female; Gentamicins; Humans; I

1994
Gentamicin retinal toxicity after cataract surgery in an eye that underwent vitrectomy.
    Ophthalmic surgery and lasers, 1997, Volume: 28, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Cataract; Eye Injuries; Fluorescein Angiography; Follow-Up Studies; Fu

1997
Gentamicin toxicity in the primate retina.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1989, Volume: 107, Issue:1

    Topics: Animals; Cebus; Gentamicins; Radiography; Retina; Retinal Diseases

1989
Macular infarction after endophthalmitis treated with vitrectomy and intravitreal gentamicin.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1986, Volume: 104, Issue:3

    Topics: Adult; Endophthalmitis; Eye Injuries; Female; Fluorescein Angiography; Gentamicins; Humans; Infarcti

1986
Acute ischemic retinopathy due to gentamicin injection.
    JAMA, 1986, Oct-03, Volume: 256, Issue:13

    Topics: Acute Disease; Gentamicins; Humans; Ischemia; Medication Errors; Necrosis; Retinal Diseases

1986