gentamicin has been researched along with Renal Insufficiency, Chronic in 12 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
| Excerpt | Relevance | Reference |
|---|---|---|
| " Likewise, de-indexation of eGFR to body surface area (BSA) has been recommended by regulatory guidance for drug dosing in renal impairment." | 1.91 | Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles. ( Abdelnabi, M; Pai, MP; Sitaruno, S, 2023) |
| "Symmetric dimethylarginine (SDMA) is an excretory renal function biomarker shown to correlate well with glomerular filtration rate in dogs, cats, humans, and rats." | 1.72 | Evaluation of Renal Biomarkers, Including Symmetric Dimethylarginine, following Gentamicin-Induced Proximal Tubular Injury in the Rat. ( Coyne, MJ; Cross, J; Drake, C; Hamlin, DM; Leissinger, MK; Mack, R; McCrann, DJ; Murphy, RE; Schultze, AE; Strong-Townsend, M; Yerramilli, M, 2022) |
| "Aminoglycoside clearance depends on kidney function, but the Australian Therapeutic Guidelines for antibiotics (version 14, 2010) recommend initial dosing based on weight without consideration of kidney function." | 1.42 | Assessment of aminoglycoside dosing and estimated glomerular filtration rate in determining gentamicin and tobramycin area under the curve and clearance. ( Larmour, I; Lim, AK; Mathanasenarajah, G, 2015) |
| "Moxifloxacin was added as an anti-chlamydial agent, but neurologic symptoms returned." | 1.42 | [Infective endocarditis caused by Chlamydia pneumoniae after liver transplantation. Case report]. ( Balla, J; Fehérvári, I; Kertész, A; Nemes, B; P Szabó, R; Szerafin, T; Zsom, L, 2015) |
| "Gentamicin clearance was calculated from plasma concentrations using a one-compartment model." | 1.39 | The performances of the Cockcroft-Gault, modification of diet in renal disease study and chronic kidney disease epidemiology collaboration equations in predicting gentamicin clearance. ( Begg, EJ; Chin, PK; Florkowski, CM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 5 (41.67) | 2.80 |
| Authors | Studies |
|---|---|
| Hamlin, DM | 1 |
| Schultze, AE | 1 |
| Coyne, MJ | 1 |
| McCrann, DJ | 1 |
| Mack, R | 1 |
| Drake, C | 1 |
| Murphy, RE | 1 |
| Cross, J | 1 |
| Strong-Townsend, M | 1 |
| Yerramilli, M | 1 |
| Leissinger, MK | 1 |
| Alharbi, KS | 1 |
| Ali, T | 1 |
| Singh, Y | 1 |
| Ali Al-Ghamdi, AS | 1 |
| Kazmi, I | 1 |
| Al-Abbasi, FA | 1 |
| Alzarea, SI | 1 |
| Afzal, O | 1 |
| Alfawaz Altamimi, AS | 1 |
| Singh, SK | 1 |
| Chellappan, DK | 1 |
| Dua, K | 1 |
| Gupta, G | 1 |
| Pai, MP | 3 |
| Sitaruno, S | 3 |
| Abdelnabi, M | 3 |
| Good, PI | 1 |
| Li, L | 1 |
| Hurst, HA | 1 |
| Serrano Herrera, I | 1 |
| Xu, K | 1 |
| Rao, M | 1 |
| Bateman, DA | 1 |
| Al-Awqati, Q | 1 |
| D'Agati, VD | 1 |
| Costantini, F | 1 |
| Lin, F | 1 |
| Dagneaux, L | 1 |
| Limberg, AK | 1 |
| Osmon, DR | 1 |
| Leung, N | 1 |
| Berry, DJ | 1 |
| Abdel, MP | 1 |
| Goh, TL | 1 |
| Wei, J | 1 |
| Semple, D | 1 |
| Collins, J | 1 |
| Ramírez Hidalgo, M | 1 |
| Jover-Sáenz, A | 1 |
| García-González, M | 1 |
| Barcenilla-Gaite, F | 1 |
| Chin, PK | 2 |
| Florkowski, CM | 2 |
| Begg, EJ | 2 |
| Bosomworth, MP | 1 |
| Sandoe, JA | 1 |
| Chew-Harris, JS | 1 |
| Lim, AK | 1 |
| Mathanasenarajah, G | 1 |
| Larmour, I | 1 |
| P Szabó, R | 1 |
| Kertész, A | 1 |
| Szerafin, T | 1 |
| Fehérvári, I | 1 |
| Zsom, L | 1 |
| Balla, J | 1 |
| Nemes, B | 1 |
1 review available for gentamicin and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Biochemical interaction of pyrvinium in gentamicin-induced acute kidney injury by modulating calcium dyshomeostasis and mitochondrial dysfunction.
Topics: Acute Kidney Injury; beta Catenin; Calcium; Gentamicins; Humans; Mitochondria; Pyrvinium Compounds; | 2022 |
11 other studies available for gentamicin and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Evaluation of Renal Biomarkers, Including Symmetric Dimethylarginine, following Gentamicin-Induced Proximal Tubular Injury in the Rat.
Topics: Animals; Arginine; Biomarkers; Dog Diseases; Dogs; Gentamicins; Kidney; Rats; Renal Insufficiency, C | 2022 |
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula | 2023 |
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula | 2023 |
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula | 2023 |
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula | 2023 |
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula | 2023 |
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula | 2023 |
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula | 2023 |
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula | 2023 |
Removing race and body surface area indexation for estimated kidney function based drug dosing: Aminoglycosides as justification of these principles.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Body Surface Area; Creatinine; Gentamicins; Glomerula | 2023 |
Low nephron endowment increases susceptibility to renal stress and chronic kidney disease.
Topics: Acute Kidney Injury; Animals; Female; Gentamicins; Humans; Hypertrophy; Infant, Premature; Kidney; M | 2023 |
Acute Kidney Injury When Treating Periprosthetic Joint Infections After Total Knee Arthroplasties with Antibiotic-Loaded Spacers: Incidence, Risks, and Outcomes.
Topics: Acute Kidney Injury; Administration, Oral; Adult; Aged; Aged, 80 and over; Amphotericin B; Anti-Bact | 2021 |
The incidence and costs of bacteremia due to lack of gentamicin lock solutions for dialysis catheters.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Catheter-Related Infections; Catheters, Indwelling; | 2017 |
Dalbavancin treatment of prosthetic knee infection due to oxacillin-resistant Staphylococcus epidermidis.
Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Device Removal; Drug Resistance, Multiple, B | 2018 |
The performances of the Cockcroft-Gault, modification of diet in renal disease study and chronic kidney disease epidemiology collaboration equations in predicting gentamicin clearance.
Topics: Adolescent; Adult; Aged; Cooperative Behavior; Creatinine; Diet; Female; Gentamicins; Humans; Male; | 2013 |
Drug dosing and estimates of kidney function.
Topics: Cooperative Behavior; Diet; Female; Gentamicins; Humans; Male; Models, Biological; Renal Insufficien | 2013 |
The performance of contemporary cystatin C-based GFR equations in predicting gentamicin clearance.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Body Mass Index; Creatinine; Cyst | 2015 |
Assessment of aminoglycoside dosing and estimated glomerular filtration rate in determining gentamicin and tobramycin area under the curve and clearance.
Topics: Adolescent; Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Area Under Curve; Dose-Response Rel | 2015 |
[Infective endocarditis caused by Chlamydia pneumoniae after liver transplantation. Case report].
Topics: Anti-Bacterial Agents; Antibodies, Bacterial; Aortic Valve; Aphasia; Brain; Calcineurin; Ceftriaxone | 2015 |