gentamicin has been researched along with Potassium Deficiency in 3 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Potassium Deficiency: A condition due to decreased dietary intake of potassium, as in starvation or failure to administer in intravenous solutions, or to gastrointestinal loss in diarrhea, chronic laxative abuse, vomiting, gastric suction, or bowel diversion. Severe potassium deficiency may produce muscular weakness and lead to paralysis and respiratory failure. Muscular malfunction may result in hypoventilation, paralytic ileus, hypotension, muscle twitches, tetany, and rhabomyolysis. Nephropathy from potassium deficit impairs the concentrating mechanism, producing POLYURIA and decreased maximal urinary concentrating ability with secondary POLYDIPSIA. (Merck Manual, 16th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with indomethacin significantly improved CIn and CPAH, and potassium repletion abolished this effect entirely." | 1.27 | Captopril enhances aminoglycoside nephrotoxicity in potassium-depleted rats. ( Baker, JD; Boatman, JE; Klotman, PE; Volpp, BD; Yarger, WE, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brinker, KR | 1 |
| Bulger, RE | 1 |
| Dobyan, DC | 1 |
| Stacey, TR | 1 |
| Southern, PM | 1 |
| Henrich, WL | 1 |
| Cronin, RE | 1 |
| Klotman, PE | 1 |
| Boatman, JE | 1 |
| Volpp, BD | 1 |
| Baker, JD | 1 |
| Yarger, WE | 1 |
| Young, GP | 1 |
| Sullivan, J | 1 |
| Hurley, T | 1 |
3 other studies available for gentamicin and Potassium Deficiency
| Article | Year |
|---|---|
Effect of potassium depletion on gentamicin nephrotoxicity.
Topics: Animals; Calcium; Creatinine; Dogs; Gentamicins; Glycosuria; Kidney; Magnesium; Phosphorus; Potassiu | 1981 |
Captopril enhances aminoglycoside nephrotoxicity in potassium-depleted rats.
Topics: Aminoglycosides; Angiotensin-Converting Enzyme Inhibitors; Animals; Aprotinin; Captopril; Gentamicin | 1985 |
Letter: Hypokalaemia due to gentamicin-cephalexin in leukaemia.
Topics: Antibiotics, Antineoplastic; Cephalexin; Drug Therapy, Combination; Gentamicins; Humans; Hypokalemia | 1973 |