gentamicin has been researched along with Patency of the Ductus Arteriosus in 18 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Birth weight, the 10-minute Apgar score and gentamicin were particularly associated with acute kidney injuries in our cohort." | 7.91 | Birth weight, Apgar scores and gentamicin were associated with acute kidney injuries in VLBW neonates requiring treatment for patent ductus arteriosus. ( Aygün, A; Ebrahimi-Fakhari, D; Gortner, L; Meyer, S; Poryo, M; Wagenpfeil, G; Wissing, A; Zemlin, M, 2019) |
| "Birth weight, the 10-minute Apgar score and gentamicin were particularly associated with acute kidney injuries in our cohort." | 3.91 | Birth weight, Apgar scores and gentamicin were associated with acute kidney injuries in VLBW neonates requiring treatment for patent ductus arteriosus. ( Aygün, A; Ebrahimi-Fakhari, D; Gortner, L; Meyer, S; Poryo, M; Wagenpfeil, G; Wissing, A; Zemlin, M, 2019) |
| "To evaluate the risk of nonsteroidal anti-inflammatory drug (NSAID) therapy-associated acute kidney injury (AKI) among neonates diagnosed with patent ductus arteriosus (PDA) who are treated with gentamicin." | 3.85 | Risk of nonsteroidal anti-inflammatory drug-associated renal dysfunction among neonates diagnosed with patent ductus arteriosus and treated with gentamicin. ( Balch, A; Constance, JE; Korgenski, EK; Reith, D; Sherwin, CMT; Stockmann, C; Thorell, EA; Ward, RM, 2017) |
| "Term neonates with unrepaired CHD who received gentamicin for empiric treatment of sepsis were identified over a 3-year period." | 3.78 | Use of 4-mg/kg/24-hour empiric aminoglycoside dosing in preoperative neonates with congenital heart disease. ( Moffett, BS; Rossano, JW, 2012) |
| "Gentamicin clearance was decreased in the patent ductus arteriosus group vs." | 2.68 | Gentamicin pharmacokinetics in neonates with patent ductus arteriosus. ( Carlos, RQ; Gal, P; Ransom, JL; Schall, SA; Smith, M; Williams, BS, 1997) |
| "Gentamicin was given to more infants with hsPDA than to those without hsPDA (89." | 1.72 | Relationship between Gentamicin Administration and Ductal Patency in Very Low Birth Weight Infants. ( Cakir, U; Tayman, C, 2022) |
| "Rates of patent ductus arteriosus (PDA) and infection are high in preterm infants." | 1.56 | Standard-dose gentamicin does not increase risk of patent ductus arteriosus. ( Akaike, T; Kishibuchi, A; Minamisawa, S, 2020) |
| "Here is a case of a female with patent ductus arteriosus, who was apparently in quite good state of health and gave birth to six offsprings without herself having any problem." | 1.48 | Patent Ductus Arteriosus with Infective Vegetations in Grandmultipara. ( Siddiqa, A; Sohail, N, 2018) |
| "All VLBW infants examined for hearing impairment were included and data were retrieved retrospectively and analyzed for neonatal risk factors using logistic regression." | 1.46 | Prevalence and independent risk factors for hearing impairment among very low birth weight infants. ( Chiang, MC; Chu, SM; Fu, RH; Hsu, JF; Lien, R; Wang, CH; Yang, CY, 2017) |
| "However, the presence of a patent ductus arteriosus, concomitant non-steroidal anti-inflammatory drug use, ≥1 positive blood cultures, low birth weight and higher severity of illness and risk of mortality scores were associated with an increased risk of nephrotoxicity." | 1.43 | A propensity-matched cohort study of vancomycin-associated nephrotoxicity in neonates. ( Balch, AH; Constance, JE; Korgenski, EK; Linakis, MW; Roberts, JK; Sherwin, CM; Spigarelli, MG; Stockmann, C; Ward, RM, 2016) |
| "Pretreatment with indomethacin and N-(G)-nitro-L-arginine methyl ester did not prevent gentamicin-induced DA relaxation." | 1.40 | Aminoglycoside-mediated relaxation of the ductus arteriosus in sepsis-associated PDA. ( Brown, N; Clark, RH; Cotton, RB; Ehinger, NJ; Goettel, JA; Paria, BC; Poole, SD; Reese, J; Rojas, MA; Shelton, EL; Slaughter, JC; Vucovich, MM; Wynn, JL, 2014) |
| " A 10-percent difference of gentamicin pharmacokinetic parameters between PDA and CDA has been reported; but its implications are unclear." | 1.31 | Gentamicin pharmacokinetics in preterm infants with a patent and a closed ductus arteriosus. ( Lafeber, HN; Proost, JH; Stevens, R; Touw, DJ; van Weissenbruch, MM, 2001) |
| "We developed a simplified gentamicin dosing protocol for all neonates using a loading dose and once-daily dosing that would have an equal or lower incidence of toxicity and an equal or improved effectiveness compared with a regimen with no loading dose that included use of divided daily dosing." | 1.30 | Once-daily gentamicin dosing in newborn infants. ( Cohen, RS; Glasscock, GF; Kim, EH; Lundergan, FS, 1999) |
| "The effect of patent ductus arteriosus (PDA) and its therapy on the pharmacokinetic disposition of gentamicin in very low birth weight neonates was studied." | 1.27 | Effect of patent ductus arteriosus on gentamicin pharmacokinetics in very low birth weight (less than 1,500 g) babies. ( Aldrich, M; Angelus, P; Johnson, JD; Kelly, HW; Watterberg, KL, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.11) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 1 (5.56) | 29.6817 |
| 2010's | 10 (55.56) | 24.3611 |
| 2020's | 2 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Cakir, U | 1 |
| Tayman, C | 1 |
| Constance, JE | 2 |
| Reith, D | 1 |
| Ward, RM | 2 |
| Balch, A | 1 |
| Stockmann, C | 2 |
| Korgenski, EK | 2 |
| Thorell, EA | 1 |
| Sherwin, CMT | 1 |
| Siddiqa, A | 1 |
| Sohail, N | 1 |
| Aygün, A | 1 |
| Poryo, M | 1 |
| Wagenpfeil, G | 1 |
| Wissing, A | 1 |
| Ebrahimi-Fakhari, D | 1 |
| Zemlin, M | 1 |
| Gortner, L | 1 |
| Meyer, S | 1 |
| Kishibuchi, A | 1 |
| Akaike, T | 1 |
| Minamisawa, S | 1 |
| Vucovich, MM | 1 |
| Cotton, RB | 2 |
| Shelton, EL | 1 |
| Goettel, JA | 1 |
| Ehinger, NJ | 1 |
| Poole, SD | 1 |
| Brown, N | 1 |
| Wynn, JL | 1 |
| Paria, BC | 1 |
| Slaughter, JC | 1 |
| Clark, RH | 1 |
| Rojas, MA | 1 |
| Reese, J | 2 |
| Balch, AH | 1 |
| Linakis, MW | 1 |
| Roberts, JK | 1 |
| Sherwin, CM | 1 |
| Spigarelli, MG | 1 |
| Wang, CH | 1 |
| Yang, CY | 1 |
| Lien, R | 1 |
| Chu, SM | 1 |
| Hsu, JF | 1 |
| Fu, RH | 1 |
| Chiang, MC | 1 |
| Veldman, A | 1 |
| Shah, L | 1 |
| Vucovich, M | 1 |
| Mittal, SR | 1 |
| Maheshwari, M | 1 |
| Kent, AL | 1 |
| Brown, L | 1 |
| Broom, M | 1 |
| Broomfield, A | 1 |
| Dahlstrom, JE | 1 |
| Moffett, BS | 1 |
| Rossano, JW | 1 |
| Williams, BS | 1 |
| Ransom, JL | 1 |
| Gal, P | 1 |
| Carlos, RQ | 1 |
| Smith, M | 1 |
| Schall, SA | 1 |
| van den Anker, JN | 1 |
| Kearns, GL | 1 |
| Lundergan, FS | 1 |
| Glasscock, GF | 1 |
| Kim, EH | 1 |
| Cohen, RS | 1 |
| Touw, DJ | 1 |
| Proost, JH | 1 |
| Stevens, R | 1 |
| Lafeber, HN | 1 |
| van Weissenbruch, MM | 1 |
| Watterberg, KL | 1 |
| Kelly, HW | 1 |
| Johnson, JD | 1 |
| Aldrich, M | 1 |
| Angelus, P | 1 |
| Zarfin, Y | 1 |
| Koren, G | 1 |
| Maresky, D | 1 |
| Perlman, M | 1 |
| MacLeod, S | 1 |
1 review available for gentamicin and Patency of the Ductus Arteriosus
| Article | Year |
|---|---|
Inadvertent relaxation of the ductus arteriosus by pharmacologic agents that are commonly used in the neonatal period.
Topics: Animals; Cimetidine; Ductus Arteriosus; Ductus Arteriosus, Patent; Gentamicins; Heparin; Histamine H | 2010 |
1 trial available for gentamicin and Patency of the Ductus Arteriosus
| Article | Year |
|---|---|
Gentamicin pharmacokinetics in neonates with patent ductus arteriosus.
Topics: Anti-Bacterial Agents; Cohort Studies; Ductus Arteriosus, Patent; Gentamicins; Gestational Age; Huma | 1997 |
16 other studies available for gentamicin and Patency of the Ductus Arteriosus
| Article | Year |
|---|---|
Relationship between Gentamicin Administration and Ductal Patency in Very Low Birth Weight Infants.
Topics: Ductus Arteriosus, Patent; Gentamicins; Humans; Infant; Infant, Newborn; Infant, Premature; Infant, | 2022 |
Risk of nonsteroidal anti-inflammatory drug-associated renal dysfunction among neonates diagnosed with patent ductus arteriosus and treated with gentamicin.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Case-Control St | 2017 |
Patent Ductus Arteriosus with Infective Vegetations in Grandmultipara.
Topics: Adult; Aspirin; Ductus Arteriosus, Patent; Echocardiography; Endocarditis, Bacterial; Female; Fever; | 2018 |
Birth weight, Apgar scores and gentamicin were associated with acute kidney injuries in VLBW neonates requiring treatment for patent ductus arteriosus.
Topics: Acute Kidney Injury; Apgar Score; Birth Weight; Ductus Arteriosus, Patent; Female; Gentamicins; Huma | 2019 |
Standard-dose gentamicin does not increase risk of patent ductus arteriosus.
Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Ductus Arteriosus, Patent; Gentamicins; Rats; Rats | 2020 |
Aminoglycoside-mediated relaxation of the ductus arteriosus in sepsis-associated PDA.
Topics: Animals; Chemokine CXCL12; Ductus Arteriosus; Ductus Arteriosus, Patent; Gentamicins; Humans; In Vit | 2014 |
A propensity-matched cohort study of vancomycin-associated nephrotoxicity in neonates.
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Bacteremia; Coh | 2016 |
Prevalence and independent risk factors for hearing impairment among very low birth weight infants.
Topics: Anti-Bacterial Agents; Craniofacial Abnormalities; Diuretics; Ductus Arteriosus, Patent; Evoked Pote | 2017 |
Patent ductus arteriosus with infective endarteritis.
Topics: Adult; Ductus Arteriosus, Patent; Echocardiography, Doppler; Endarteritis; Enterococcus faecalis; Fe | 2010 |
Increased urinary podocytes following indomethacin suggests drug-induced glomerular injury.
Topics: Anti-Bacterial Agents; Cardiovascular Agents; Drug Therapy, Combination; Ductus Arteriosus, Patent; | 2012 |
Use of 4-mg/kg/24-hour empiric aminoglycoside dosing in preoperative neonates with congenital heart disease.
Topics: Alprostadil; Anti-Bacterial Agents; Critical Illness; Drug Administration Schedule; Ductus Arteriosu | 2012 |
Gentamicin pharmacokinetics in neonates with patent ductus arteriosus.
Topics: Anti-Bacterial Agents; Ductus Arteriosus, Patent; Gentamicins; Humans; Infant, Newborn | 1997 |
Once-daily gentamicin dosing in newborn infants.
Topics: Bacterial Infections; Clinical Protocols; Cohort Studies; Drug Administration Schedule; Ductus Arter | 1999 |
Gentamicin pharmacokinetics in preterm infants with a patent and a closed ductus arteriosus.
Topics: Anti-Bacterial Agents; Chi-Square Distribution; Ductus Arteriosus; Ductus Arteriosus, Patent; Female | 2001 |
Effect of patent ductus arteriosus on gentamicin pharmacokinetics in very low birth weight (less than 1,500 g) babies.
Topics: Ductus Arteriosus, Patent; Gentamicins; Half-Life; Humans; Infant, Low Birth Weight; Infant, Newborn | 1987 |
Possible indomethacin-aminoglycoside interaction in preterm infants.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Creatinine; Diuresis; Drug Interactions; Ductus Ar | 1985 |