gentamicin has been researched along with Osteoarthritis of Knee in 8 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Excerpt | Relevance | Reference |
---|---|---|
"Reduction of postoperative pain was associated with a decrease in C-reactive protein level and earlier achievement of straight leg raise." | 2.78 | Local infusion analgesia using intra-articular double lumen catheter after total knee arthroplasty: a double blinded randomized control study. ( Fukunaga, K; Ikeuchi, M; Izumi, M; Kamimoto, Y; Sugimura, N; Takemura, M; Tani, T; Yokoyama, M, 2013) |
"The timing of the diagnosis of the infection after knee arthroplasty was of the prosthesis averaged 11." | 1.30 | [One-stage reimplantation for the salvage of total knee arthroplasty complicated by infection]. ( Kou, B; Lin, J; Lu, H, 1997) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (12.50) | 18.2507 |
2000's | 1 (12.50) | 29.6817 |
2010's | 6 (75.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Wittmann, D | 1 |
Summer, B | 1 |
Thomas, B | 1 |
Halder, A | 1 |
Thomas, P | 1 |
Xu, H | 1 |
Wang, C | 1 |
Zhang, H | 1 |
Wang, Y | 1 |
Yuan, N | 1 |
Liu, Y | 1 |
Li, X | 1 |
Zhang, L | 1 |
Hou, M | 1 |
Li, Y | 1 |
Li, Z | 1 |
Ahmad, SS | 1 |
Huber, K | 1 |
Evangelopoulos, DS | 1 |
Kleer, B | 1 |
Kohlhof, H | 1 |
Schär, M | 1 |
Eggli, S | 1 |
Kohl, S | 1 |
Molt, M | 1 |
Toksvig-Larsen, S | 1 |
Ikeuchi, M | 2 |
Kamimoto, Y | 2 |
Izumi, M | 2 |
Sugimura, N | 2 |
Takemura, M | 1 |
Fukunaga, K | 2 |
Yokoyama, M | 2 |
Tani, T | 2 |
Aso, K | 1 |
van Raaij, TM | 1 |
Visser, LE | 1 |
Vulto, AG | 1 |
Verhaar, JA | 1 |
Lu, H | 1 |
Kou, B | 1 |
Lin, J | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
In Vivo Stability of an Uncemented Total Knee Arthroplasty With Medially Stabilized Design[NCT04017533] | 30 participants (Anticipated) | Interventional | 2021-09-04 | Recruiting | |||
Evaluation of Triathlon - a New Total Knee Prosthesis System. Prospective, Comparative, Randomised, Roentgen Stereophotogrammetric Analysis (RSA) Series[NCT00436982] | 60 participants (Actual) | Interventional | 2006-02-28 | Completed | |||
Pre-emptive Scalp Infiltration With Dexamethasone Plus Ropivacaine for Post-Craniotomy Pain in Children[NCT04051723] | Phase 4 | 80 participants (Actual) | Interventional | 2019-09-02 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
(NCT00436982)
Timeframe: preoperative to discharge
Intervention | days (Mean) |
---|---|
Triathlon | 4.9 |
Duracon | 4.76 |
Skin to skin operative time (NCT00436982)
Timeframe: intra-operative
Intervention | minutes (Mean) |
---|---|
Triathlon | 66.47 |
Duracon | 63.7 |
To compare the maximum total point motion (MTPM) of the Triathlon and Duracon tibial components at two years assessed by means of RSA. (NCT00436982)
Timeframe: 2 years
Intervention | mm (Mean) |
---|---|
Triathlon | 0.65 |
Duracon | 0.81 |
"The EQ-5D is a subject-completed questionnaire designed to assess subject health state values. The EQ-5D consists of 2 areas; the EQ visual analogue scale (EQ VAS) and EQ-5D descriptive system. The EQ VAS collects health state values using a 20 cm visual analogue scale with the endpoints labeled best imaginable health state at the top and worst imaginable health state at the bottom, having numeric values of 100 to 0 respectively. The EQ-5D Time Trade-off (TTO) descriptive system comprises the following five dimensions: mobility, self-care, usual activities, pain/comfort and anxiety/depression. Each dimension has three levels: no problems, some problems and extreme problems, where an overall score of 1 represents full health.~NOTE: While the protocol includes pre-operative, 3 months, and 1 year, this data was not collected." (NCT00436982)
Timeframe: pre-operative, 3 months, 1, 2, 5, 7 and 10 years
Intervention | units on a scale (Mean) | |||
---|---|---|---|---|
EQ-5D 2 years | EQ-5D 5 years | EQ-5D 7 years | EQ-5D 10 years | |
Duracon Total Knee System | 0.79 | 0.76 | 0.86 | 0.78 |
Triathlon Total Knee System | 0.80 | 0.78 | 0.73 | 0.75 |
"KOOS consists of 5 subscales; Pain, other Symptoms, Activities of Daily Living (ADL), Sport and Recreation Function (Sport/Rec) and knee-related Quality of Life (QOL). The previous week is the time period considered when answering the questions. Standardized answer options are given (5 Likert boxes) and each question is assigned a score from 0 to 4. A normalized score (100 indicating no symptoms and 0 indicating extreme symptoms) is calculated for each subscale.~[taken from User Guide] http://www.koos.nu/" (NCT00436982)
Timeframe: pre-operative, 3 months, 1, 2, 5, 7 and 10 years
Intervention | units on a scale (Mean) | ||||||||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
QOL pre-operative | QOL 3 months | QOL 1 year | QOL 2 years | QOL 5 years | QOL 7 years | QOL 10 years | Symptoms preoperative | Symptoms 3 months | Symptoms 1 year | Symptoms 2 years | Symptoms 5 years | Symptoms 7 years | Symptoms 10 years | Pain preoperative | Pain 3 months | Pain 1 year | Pain 2 years | Pain 5 years | Pain 7 years | Pain 10 years | ADL preoperative | ADL 3 months | ADL 1 year | ADL 2 years | ADL 5 years | ADL 7 years | ADL 10 years | Sport/Rec preOP | Sport/Rec 3 months | Sport/Rec 1 year | Sport/Rec 2 years | Sport/Rec 5 years | Sport/Rec 7 years | Sport/Rec 10 years | |
Cemented Triathlon Total Knee System | 23.75 | 51.79 | 58.48 | 62.73 | 69.87 | 68.75 | 65.83 | 51.25 | 66.84 | 75.51 | 78.17 | 81.81 | 82.14 | 81.62 | 42.11 | 70.57 | 73.64 | 79.94 | 81.31 | 80.56 | 80.74 | 47.27 | 73.22 | 74.28 | 76.74 | 78.07 | 75.25 | 73.21 | 6.5 | 20.19 | 30.46 | 28.65 | 36.14 | 22.5 | 25.33 |
Duracon Total Knee System | 24.38 | 54.09 | 65.51 | 71.35 | 80.06 | 86.33 | 73.53 | 53.65 | 65.87 | 77.51 | 81.87 | 83.16 | 92.63 | 88.45 | 43.61 | 70.21 | 82.77 | 84.82 | 85.45 | 91.15 | 84.31 | 50.14 | 73.35 | 84.42 | 84.90 | 83.05 | 89.34 | 80.02 | 10 | 29.55 | 38.65 | 46.17 | 38.33 | 44.06 | 50.15 |
"The Knee Society Clinical Rating System is comprised of two distinct sub-scores: one for pain, ROM and joint stability, and one for functional parameters. Sub-scores range from a potential minimum score of 0 to a maximum score of 100 points. Although the specific scores are not distinguished as excellent, good, fair, or poor, a higher value represents a better outcome." (NCT00436982)
Timeframe: [Time Frame: pre-operative, 3 months, 1, 2, 5, 7 and 10 years]
Intervention | units on a scale (Mean) | |||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
KSS Pain/Motion pre-operative | KSS Pain/Motion 3 months | KSS Pain/Motion 1 year | KSS Pain/Motion 2 years | KSS Pain/Motion 5 years | KSS Pain/Motion 7 years | KSS Pain/Motion 10 years | KSS Function pre-operative | KSS Function 3 months | KSS Function 1 year | KSS Function 2 years | KSS Function 5 years | KSS Function 7 years | KSS Function 10 years | |
Duracon | 18.3 | 86.55 | 95.43 | 94.79 | 94.24 | 95.13 | 96.79 | 53.67 | 72.76 | 84.42 | 88.57 | 81.67 | 92.5 | 84.38 |
Triathlon | 17.3 | 86.09 | 93.51 | 94.96 | 93.14 | 90.06 | 93.6 | 51.17 | 70 | 80 | 86.67 | 81.82 | 76.11 | 78.33 |
To compare the maximum total point motion (MTPM) of the Triathlon and Duracon tibial components by means of RSA. (NCT00436982)
Timeframe: 3 months, 1, 5, 7 and 10 years
Intervention | mm (Mean) | ||||
---|---|---|---|---|---|
MTPM 3 months | MTPM 1 year | MTPM 5 years | MTPM 7 years | MTPM 10 years | |
Cemented Triathlon Total Knee System | 0.45 | 0.6 | 0.65 | 0.67 | 0.75 |
Duracon Total Knee System | 0.44 | 0.64 | 1.1 | 0.65 | 0.6 |
3 trials available for gentamicin and Osteoarthritis of Knee
Article | Year |
---|---|
Similar early migration when comparing CR and PS in Triathlon™ TKA: A prospective randomised RSA trial.
Topics: Aged; Arthroplasty, Replacement, Knee; Cementation; Female; Follow-Up Studies; Gentamicins; Humans; | 2014 |
Similar early migration when comparing CR and PS in Triathlon™ TKA: A prospective randomised RSA trial.
Topics: Aged; Arthroplasty, Replacement, Knee; Cementation; Female; Follow-Up Studies; Gentamicins; Humans; | 2014 |
Similar early migration when comparing CR and PS in Triathlon™ TKA: A prospective randomised RSA trial.
Topics: Aged; Arthroplasty, Replacement, Knee; Cementation; Female; Follow-Up Studies; Gentamicins; Humans; | 2014 |
Similar early migration when comparing CR and PS in Triathlon™ TKA: A prospective randomised RSA trial.
Topics: Aged; Arthroplasty, Replacement, Knee; Cementation; Female; Follow-Up Studies; Gentamicins; Humans; | 2014 |
Local infusion analgesia using intra-articular double lumen catheter after total knee arthroplasty: a double blinded randomized control study.
Topics: Aged; Amides; Analgesics; Anesthetics, Local; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee | 2013 |
Effects of dexamethasone on local infiltration analgesia in total knee arthroplasty: a randomized controlled trial.
Topics: Aged; Amides; Anesthetics, Local; Anti-Bacterial Agents; Anti-Inflammatory Agents; Arthroplasty, Rep | 2014 |
5 other studies available for gentamicin and Osteoarthritis of Knee
Article | Year |
---|---|
Gentamicin allergy as an unexpected 'hidden' cause of complications in knee arthroplasty.
Topics: Aged; Arthroplasty, Replacement, Knee; Bone Cements; Dermatitis, Allergic Contact; Drug Hypersensiti | 2018 |
Topics: Arthroplasty, Replacement, Knee; Bone Cements; Calcium Sulfate; Chitosan; Compressive Strength; Foll | 2017 |
The cement prosthesis-like spacer: an intermediate halt on the road to healing.
Topics: Arthritis, Infectious; Arthroplasty, Replacement, Knee; Bone Cements; Debridement; Enterococcus; Gen | 2013 |
Acute renal failure after local gentamicin treatment in an infected total knee arthroplasty.
Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee | 2002 |
[One-stage reimplantation for the salvage of total knee arthroplasty complicated by infection].
Topics: Adult; Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Female; Follow-Up Studies; Gent | 1997 |