gentamicin and Osteoarthritis, Knee

gentamicin has been researched along with Osteoarthritis, Knee in 8 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Osteoarthritis, Knee: Noninflammatory degenerative disease of the knee joint consisting of three large categories: conditions that block normal synchronous movement, conditions that produce abnormal pathways of motion, and conditions that cause stress concentration resulting in changes to articular cartilage. (Crenshaw, Campbell's Operative Orthopaedics, 8th ed, p2019)

Research

Studies (8)

Authors

Clinical Trials (3)

Trial Overview

Trial Outcomes

Duration Hospital Stay

(NCT00436982)
Timeframe: preoperative to discharge

Mean Operative Time

Skin to skin operative time (NCT00436982)
Timeframe: intra-operative

Roentgen Stereophotogrammetric Analysis (RSA)

To compare the maximum total point motion (MTPM) of the Triathlon and Duracon tibial components at two years assessed by means of RSA. (NCT00436982)
Timeframe: 2 years

Investigation of Clinical Performance and Patient Outcome With EQ-5D Patient Questionnaire

"The EQ-5D is a subject-completed questionnaire designed to assess subject health state values. The EQ-5D consists of 2 areas; the EQ visual analogue scale (EQ VAS) and EQ-5D descriptive system. The EQ VAS collects health state values using a 20 cm visual analogue scale with the endpoints labeled best imaginable health state at the top and worst imaginable health state at the bottom, having numeric values of 100 to 0 respectively. The EQ-5D Time Trade-off (TTO) descriptive system comprises the following five dimensions: mobility, self-care, usual activities, pain/comfort and anxiety/depression. Each dimension has three levels: no problems, some problems and extreme problems, where an overall score of 1 represents full health.~NOTE: While the protocol includes pre-operative, 3 months, and 1 year, this data was not collected." (NCT00436982)
Timeframe: pre-operative, 3 months, 1, 2, 5, 7 and 10 years

Investigation of Clinical Performance and Patient Outcome With KOOS Patient Questionnaire

"KOOS consists of 5 subscales; Pain, other Symptoms, Activities of Daily Living (ADL), Sport and Recreation Function (Sport/Rec) and knee-related Quality of Life (QOL). The previous week is the time period considered when answering the questions. Standardized answer options are given (5 Likert boxes) and each question is assigned a score from 0 to 4. A normalized score (100 indicating no symptoms and 0 indicating extreme symptoms) is calculated for each subscale.~[taken from User Guide] http://www.koos.nu/" (NCT00436982)
Timeframe: pre-operative, 3 months, 1, 2, 5, 7 and 10 years

Investigation of Clinical Performance and Patient Outcome With KSS (Knee Society Score)

"The Knee Society Clinical Rating System is comprised of two distinct sub-scores: one for pain, ROM and joint stability, and one for functional parameters. Sub-scores range from a potential minimum score of 0 to a maximum score of 100 points. Although the specific scores are not distinguished as excellent, good, fair, or poor, a higher value represents a better outcome." (NCT00436982)
Timeframe: [Time Frame: pre-operative, 3 months, 1, 2, 5, 7 and 10 years]

Roentgen Stereophotogrammetric Analysis (RSA)

To compare the maximum total point motion (MTPM) of the Triathlon and Duracon tibial components by means of RSA. (NCT00436982)
Timeframe: 3 months, 1, 5, 7 and 10 years

Trials

3 trials available for gentamicin and Osteoarthritis, Knee

Other Studies

5 other studies available for gentamicin and Osteoarthritis, Knee