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gentamicin and Ophthalmia Neonatorum

gentamicin has been researched along with Ophthalmia Neonatorum in 9 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Ophthalmia Neonatorum: Acute conjunctival inflammation in the newborn, usually caused by maternal gonococcal infection. The causative agent is NEISSERIA GONORRHOEAE. The baby's eyes are contaminated during passage through the birth canal.

Research Excerpts

ExcerptRelevanceReference
"Crede's method was evaluated using norfloxacin (NFLX) and gentamicin (GM) to show the clinical significance of chemoprophylaxis against ophthalmia neonatorum occurring through vertical infections."7.68[Chemoprophylaxis of ophthalmia neonatorum through vertical infection. Evaluation of Crede's method using norfloxacin and gentamicin]. ( Seiga, K; Shoji, T, 1993)
"Crede's method was evaluated using of ofloxacin (OFLX) and gentamicin (GM) to show the clinical significance of chemoprophylaxis against ophthalmia neonatorum occurring through vertical infection."7.68[Chemoprophylaxis of ophthalmia neonatorum through vertical infection. Evaluation of Crede's method using ofloxacin and gentamicin]. ( Seiga, K; Shoji, T; Sugiyama, Y, 1990)
"We conducted a randomized clinical trial comparing a single intramuscular dose of 125 mg of ceftriaxone with a single intramuscular dose of 75 mg of kanamycin followed by topical gentamicin for seven days, and with a single intramuscular dose of 75 mg of kanamycin followed by topical tetracycline for seven days, in the treatment of gonococcal ophthalmia neonatorum in Nairobi, Kenya."5.06Single-dose therapy of gonococcal ophthalmia neonatorum with ceftriaxone. ( Brunham, RC; D'Costa, LJ; Kunimoto, D; Laga, M; Naamara, W; Ndinya-Achola, JO; Nsanze, H; Piot, P; Ronald, AR; Slaney, L, 1986)
"117 infants with gonococcal ophthalmia neonatorum, including 27 with infections due to penicillinase-producing Neisseria gonorrhoeae, were treated as outpatients with five different regimens of single-dose intramuscular kanamycin (75 mg or 150 mg) with saline eye washes, gentamicin eye ointment, or chloramphenicol eye drops."5.05Single-dose kanamycin therapy of gonococcal ophthalmia neonatorum. ( Brunham, RC; D'Costa, L; Fransen, L; Nsanze, H; Piot, P; Ronald, AR, 1984)
" 25% of the routine applicants are using substances (Gentamicin, Neomycin or Chloramphenicol) for which no evidence based efficacy for prophylaxis of Ophthalmia neonatorum has been demonstrated through clinical trials."3.71Prophylaxis of ophthalmia neonatorum--a nationwide survey of the current practice in Austria. ( Aspöck, C; Assadian, A; Assadian, O; Hahn, D; Koller, W, 2002)
"Crede's method was evaluated using norfloxacin (NFLX) and gentamicin (GM) to show the clinical significance of chemoprophylaxis against ophthalmia neonatorum occurring through vertical infections."3.68[Chemoprophylaxis of ophthalmia neonatorum through vertical infection. Evaluation of Crede's method using norfloxacin and gentamicin]. ( Seiga, K; Shoji, T, 1993)
"Crede's method was evaluated using of ofloxacin (OFLX) and gentamicin (GM) to show the clinical significance of chemoprophylaxis against ophthalmia neonatorum occurring through vertical infection."3.68[Chemoprophylaxis of ophthalmia neonatorum through vertical infection. Evaluation of Crede's method using ofloxacin and gentamicin]. ( Seiga, K; Shoji, T; Sugiyama, Y, 1990)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19903 (33.33)18.7374
1990's3 (33.33)18.2507
2000's1 (11.11)29.6817
2010's2 (22.22)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wexelblatt, SL1
Greenberg, JM1
Nathan, AT1
Nathawad, R1
Mendez, H1
Ahmad, A1
Laungani, S1
Hoa, BT1
Garlick, J1
Hammerschlag, MR1
Assadian, O1
Assadian, A1
Aspöck, C1
Hahn, D1
Koller, W1
Fransen, L1
Nsanze, H3
D'Costa, L1
Brunham, RC2
Ronald, AR2
Piot, P2
Romanet, P1
Bouron, Y1
Glemain, P1
Seiga, K2
Shoji, T2
Dawodu, A1
Usmani, A1
Sabarinathan, K1
Varady, E1
Sugiyama, Y1
Laga, M1
Naamara, W1
D'Costa, LJ1
Kunimoto, D1
Ndinya-Achola, JO1
Slaney, L1

Trials

2 trials available for gentamicin and Ophthalmia Neonatorum

ArticleYear
Single-dose kanamycin therapy of gonococcal ophthalmia neonatorum.
    Lancet (London, England), 1984, Dec-01, Volume: 2, Issue:8414

    Topics: Administration, Topical; Chloramphenicol; Clinical Trials as Topic; Drug Therapy, Combination; Femal

1984
Single-dose therapy of gonococcal ophthalmia neonatorum with ceftriaxone.
    The New England journal of medicine, 1986, Nov-27, Volume: 315, Issue:22

    Topics: Ceftriaxone; Clinical Trials as Topic; Drug Resistance, Microbial; Follow-Up Studies; Gentamicins; H

1986

Other Studies

7 other studies available for gentamicin and Ophthalmia Neonatorum

ArticleYear
Regional care model enables rapid response to adverse drug events.
    Journal of perinatology : official journal of the California Perinatal Association, 2010, Volume: 30, Issue:4

    Topics: Administration, Topical; Adverse Drug Reaction Reporting Systems; Anti-Bacterial Agents; Drug Erupti

2010
Severe ocular reactions after neonatal ocular prophylaxis with gentamicin ophthalmic ointment.
    The Pediatric infectious disease journal, 2011, Volume: 30, Issue:2

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Gentamicins; Humans; Infant, Newborn; Ointments; Opht

2011
Prophylaxis of ophthalmia neonatorum--a nationwide survey of the current practice in Austria.
    Wiener klinische Wochenschrift, 2002, Mar-28, Volume: 114, Issue:5-6

    Topics: Anti-Infective Agents, Local; Austria; Conjunctivitis; Critical Pathways; Erythromycin; Female; Gent

2002
[Neonatal gonococcal ophthalmia].
    Archives francaises de pediatrie, 1982, Volume: 39, Issue:9

    Topics: Ampicillin; Drug Therapy, Combination; Gentamicins; Humans; Infant, Newborn; Male; Ophthalmia Neonat

1982
[Chemoprophylaxis of ophthalmia neonatorum through vertical infection. Evaluation of Crede's method using norfloxacin and gentamicin].
    The Japanese journal of antibiotics, 1993, Volume: 46, Issue:4

    Topics: Adult; Female; Gentamicins; Humans; Infant, Newborn; Norfloxacin; Ophthalmia Neonatorum; Pregnancy

1993
Ophthalmia neonatorum in the United Arab Emirates.
    Annals of tropical paediatrics, 1996, Volume: 16, Issue:1

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Ceftriaxone; Cephalosporins; Conjunctiva; Eye Infecti

1996
[Chemoprophylaxis of ophthalmia neonatorum through vertical infection. Evaluation of Crede's method using ofloxacin and gentamicin].
    The Japanese journal of antibiotics, 1990, Volume: 43, Issue:1

    Topics: Drug Resistance, Microbial; Escherichia coli; Female; Gentamicins; Humans; Infant, Newborn; Male; Of

1990