Page last updated: 2024-10-27

gentamicin and Niemann-Pick Disease, Type A

gentamicin has been researched along with Niemann-Pick Disease, Type A in 1 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Niemann-Pick Disease, Type A: The classic infantile form of Niemann-Pick Disease, caused by mutation in SPHINGOMYELIN PHOSPHODIESTERASE. It is characterized by accumulation of SPHINGOMYELINS in the cells of the MONONUCLEAR PHAGOCYTE SYSTEM and other cell throughout the body leading to cell death. Clinical signs include JAUNDICE, hepatosplenomegaly, and severe brain damage.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gómez-Grau, M1
Garrido, E1
Cozar, M1
Rodriguez-Sureda, V1
Domínguez, C1
Arenas, C1
Gatti, RA1
Cormand, B1
Grinberg, D1
Vilageliu, L1

Other Studies

1 other study available for gentamicin and Niemann-Pick Disease, Type A

ArticleYear
Evaluation of Aminoglycoside and Non-Aminoglycoside Compounds for Stop-Codon Readthrough Therapy in Four Lysosomal Storage Diseases.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: Animals; Cell Line; Chlorocebus aethiops; Codon, Nonsense; Codon, Terminator; COS Cells; Fibroblasts

2015