gentamicin has been researched along with Neutropenia in 116 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The pharmacokinetics (PK) of isepamicin were studied in 8 febrile neutropenic patients with hematologic malignancy and in 20 young women with acute pelvic inflammatory disease (PID)." | 9.11 | Key pharmacokinetic parameters of isepamicin in febrile neutropenic cancer patients and in women with acute pelvic inflammatory disease. ( Gala, JL; Leal, T; Vandercam, B; Wallemacq, P; Yombi, JC, 2005) |
| " This trial was initiated to assess the efficacy and safety of piperacillin with the beta-lactam inhibitors sulbactam (PSG group) or tazobactam (PTG group) and gentamicin as initial therapy in febrile neutropenia of pediatric patients." | 9.09 | Piperacillin, beta-lactam inhibitor plus gentamicin as empirical therapy of a sequential regimen in febrile neutropenia of pediatric cancer patients. ( Bode, U; Fleischhack, G; Hasan, C; Havers, W; Marklein, G; Schmidt-Niemann, M; Wulff, B, 2001) |
| "The efficacy of aztreonam in combination with vancomycin was compared with that of gentamicin plus piperacillin as empirical antibiotic treatment for fever in 61 neutropenic patients." | 9.07 | Aztreonam plus vancomycin versus gentamicin plus piperacillin as empirical therapy for the treatment of fever in neutropenic patients: a randomised controlled study. ( Kelsey, SM; Newland, AC; Shaw, E, 1992) |
| "Fourty-two febrile episodes of 32 patients with hematologic disease during neutropenia were treated with two randomly assigned antibiotic combinations of either piperacillin plus gentamicin or piperacillin plus aztreonam." | 9.07 | [Aztreonam or gentamicin combined with piperacillin as empiric antibiotic therapy during neutropenia of patients with hematologic diseases]. ( Murase, T, 1992) |
| "We compared the combination of teicoplanin plus ciprofloxacin with gentamicin plus piperacillin for the empirical treatment of fever in 80 neutropenic patients." | 9.06 | A randomized study of teicoplanin plus ciprofloxacin versus gentamicin plus piperacillin for the empirical treatment of fever in neutropenic patients. ( Collins, PW; Delord, C; Kelsey, SM; Newland, AC; Weinhard, B, 1990) |
| " This study compared 3 pharmacokinetic methods for predicting doses and monitoring of gentamicin in adult patients with febrile neutropenia." | 7.77 | Comparing 3 methods of monitoring gentamicin concentrations in patients with febrile neutropenia. ( Avent, ML; Eckert, KA; Kirkpatrick, CM; Lees, J; Teoh, J, 2011) |
| "To evaluate an existing once-daily gentamicin dosing guideline in children with febrile neutropenia resulting from antineoplastic therapy and, if necessary, to develop a new simulated dosing guideline that would achieve pharmacokinetic targets more reliably after the first dose." | 7.76 | Once-daily gentamicin dosing in children with febrile neutropenia resulting from antineoplastic therapy. ( Atenafu, EG; Boodhan, S; Dupuis, LL; Inparajah, M; Naqvi, A; Sibbald, C; Wong, C, 2010) |
| "We completed a study to determine if empiric use of gentamicin 7 mg/kg once daily in pediatric patients admitted with febrile neutropenia provided extrapolated peaks and drug-free intervals consistent with suggested preferred levels." | 7.75 | Assessment of gentamicin 7 mg/kg once daily for pediatric patients with febrile neutropenia: a pilot project. ( Lotocka-Reysner, H; Newby, B; Prevost, D, 2009) |
| "OD gentamicin can be used safely and effectively to treat febrile neutropenia in children with cancer." | 7.70 | Once daily ceftriaxone and gentamicin for the treatment of febrile neutropenia. ( Das, S; Goodbourne, C; Lilleyman, JS; Price, C; Ronghe, M; Saha, V; Tomlinson, RJ, 1999) |
| " Patients receiving gentamicin for febrile neutropenia may be considered pharmacokinetically similar to the general population receiving gentamicin." | 7.70 | Population analysis of once-daily dosing of gentamicin in patients with neutropenia. ( Duffull, SB; Peterson, AK, 1998) |
| "During a 12-month study, 42 adult patients with febrile neutropenia (granulocytes < 1 x 10(9)/l) were treated with once-daily gentamicin (5 mg/kg)." | 7.69 | Audit of once-daily dosing gentamicin therapy in neutropenic fever. ( Cooke, RP; Gover, PA; Grace, RJ, 1997) |
| "To report a case of ticlopidine-induced neutropenia resulting in Pseudomonas bacteremia." | 7.69 | Pseudomonas bacteremia precipitated by ticlopidine-induced neutropenia. ( Geletko, SM; Melbourne, KM; Mikolich, DJ, 1996) |
| "To minimize renal and hematological toxicity during empirical antibiotic therapy for pediatric patients with fever and neutropenia, piperacillin and gentamicin combination therapy was evaluated." | 7.67 | Piperacillin and gentamicin as non toxic empirical therapy in pediatric patients with fever and neutropenia. ( Clavell, LA; González, M, 1987) |
| " The response rate to once-daily gentamicin dosing and azlocillin was three times higher than to multiple-daily gentamicin dosing and azlocillin (P = 0." | 6.69 | Once-daily versus multiple-daily gentamicin in empirical antibiotic therapy of febrile neutropenia following intensive chemotherapy. ( Bakri, FE; Duncombe, AS; Pallett, A; Smith, AG, 2000) |
| "To evaluate the extent of agreement between plasma gentamicin concentrations determined from samples collected by using implantable subcutaneous central venous catheters (ports) with the push-pull method and those collected by finger lancet punctures in children with febrile neutropenia." | 5.15 | A reliable and safe method of collecting blood samples from implantable central venous catheters for determination of plasma gentamicin concentrations. ( Boodhan, S; Brandão, LR; Chang, A; Chen, J; Dupuis, LL; Lavoratore, S; Nanji, M; Sekharan, S; Skolnik, JM, 2011) |
| "The pharmacokinetics (PK) of isepamicin were studied in 8 febrile neutropenic patients with hematologic malignancy and in 20 young women with acute pelvic inflammatory disease (PID)." | 5.11 | Key pharmacokinetic parameters of isepamicin in febrile neutropenic cancer patients and in women with acute pelvic inflammatory disease. ( Gala, JL; Leal, T; Vandercam, B; Wallemacq, P; Yombi, JC, 2005) |
| " If fever persisted, teicoplanin plus gentamicin (group A) or teicoplanin plus ciprofloxacin (group B) were added." | 5.10 | Piperacillin-tazobactam is more effective than ceftriaxone plus gentamicin in febrile neutropenic patients with hematological malignancies: a randomized comparison. ( Fixson, A; Glasmacher, A; Gorschlüter, M; Hahn, C; Horré, R; Marklein, G; Mey, U; Molitor, E; Sauerbruch, T; Schmidt-Wolf, IG; Ziske, C, 2003) |
| " This trial was initiated to assess the efficacy and safety of piperacillin with the beta-lactam inhibitors sulbactam (PSG group) or tazobactam (PTG group) and gentamicin as initial therapy in febrile neutropenia of pediatric patients." | 5.09 | Piperacillin, beta-lactam inhibitor plus gentamicin as empirical therapy of a sequential regimen in febrile neutropenia of pediatric cancer patients. ( Bode, U; Fleischhack, G; Hasan, C; Havers, W; Marklein, G; Schmidt-Niemann, M; Wulff, B, 2001) |
| "The purpose of this study was to test the comparative efficacy and toxicity of empiric gentamicin and ciprofloxacin, in combination with piperacillin, in febrile patients with treatment-induced neutropenia." | 5.08 | Ciprofloxacin plus piperacillin is an equally effective regimen for empiric therapy in febrile neutropenic patients compared with standard therapy. ( Betts, RF; Blair, EA; Flesher, WR; Griggs, JJ; Norton, JR; Rowe, JM, 1998) |
| "Three-hundred and twelve episodes of fever in 234 neutropenic patients with haematological malignancies were treated empirically with either imipenem or a combination of piperacillin and gentamicin." | 5.07 | A comparative study of imipenem versus piperacillin plus gentamicin in the initial management of febrile neutropenic patients with haematological malignancies. ( Bareford, D; Bayston, KF; Bint, AJ; Cefai, C; Cohen, J; Leyland, MJ; Murray, SA; Newland, AC; Warren, R; White, DG, 1992) |
| "Teicoplanin plus ciprofloxacin was compared with gentamicin plus piperacillin for the empirical treatment of fever in 80 neutropenic patients." | 5.07 | Teicoplanin plus ciprofloxacin versus gentamicin plus piperacillin in the treatment of febrile neutropenic patients. ( Collins, PW; Kelsey, SM; Newland, AC; Weinhardt, B, 1992) |
| "Fourty-two febrile episodes of 32 patients with hematologic disease during neutropenia were treated with two randomly assigned antibiotic combinations of either piperacillin plus gentamicin or piperacillin plus aztreonam." | 5.07 | [Aztreonam or gentamicin combined with piperacillin as empiric antibiotic therapy during neutropenia of patients with hematologic diseases]. ( Murase, T, 1992) |
| "The efficacy of aztreonam in combination with vancomycin was compared with that of gentamicin plus piperacillin as empirical antibiotic treatment for fever in 61 neutropenic patients." | 5.07 | Aztreonam plus vancomycin versus gentamicin plus piperacillin as empirical therapy for the treatment of fever in neutropenic patients: a randomised controlled study. ( Kelsey, SM; Newland, AC; Shaw, E, 1992) |
| "To test the value of pefloxacin for the prevention of infections in patients with chemotherapy-induced neutropenia, oral pefloxacin plus vancomycin (PV) (n = 76) or gentamicin, colistin sulphate and vancomycin (GCV) (n = 74) were administered in a randomised double-blind study." | 5.07 | Pefloxacin and vancomycin vs. gentamicin, colistin sulphate and vancomycin for prevention of infections in granulocytopenic patients: a randomised double-blind study. ( Archimbaud, E; Devaux, Y; Fiere, D; Fleurette, J; Guyotat, D; Maupas, J; Nageotte, A; Ploton, C; Thomas, X, 1991) |
| "We compared the combination of teicoplanin plus ciprofloxacin with gentamicin plus piperacillin for the empirical treatment of fever in 80 neutropenic patients." | 5.06 | A randomized study of teicoplanin plus ciprofloxacin versus gentamicin plus piperacillin for the empirical treatment of fever in neutropenic patients. ( Collins, PW; Delord, C; Kelsey, SM; Newland, AC; Weinhard, B, 1990) |
| "To assess the efficacy of single-agent therapy relative to standard combination antibiotic therapy for the initial management of fever and neutropenia in cancer patients, we conducted a randomized trial comparing ceftazidime alone with a combination of cephalothin, gentamicin, and carbenicillin." | 5.06 | A randomized trial comparing ceftazidime alone with combination antibiotic therapy in cancer patients with fever and neutropenia. ( Browne, M; Commers, J; Cotton, D; Gress, J; Hathorn, JW; Hiemenz, J; Longo, D; Marshall, D; McKnight, J; Pizzo, PA, 1986) |
| "Random allocation of 22 patients with benign and malignant diseases with neutrophil counts of up to 1 X 10(9)/l blood and probably infection-caused fever of more than 38 degrees C to intravenous treatment with one of the following antibiotic combinations was performed: carbenicillin (6 g/m(2) ." | 5.05 | [Treatment of severe febrile neutropenia (author's transl)]. ( Heim, ME; Meuret, G; Roux, A; Westerhausen, M, 1980) |
| "Neutropenic cancer patients were given carbenicillin, cephalothin, and gentamicin (CCG) during 51 evaluable episodes of fever of unknown origin." | 5.04 | A study of antibiotic therapy in fever of unknown origin in neutropenic cancer patients. ( Björnsson, S; Henderson, ES; Preisler, H, 1977) |
| " This protocol would have been appropriate in 85% of all neutropenic bacteremia episodes and 89% of episodes in febrile neutropenia patients compared with piperacillin/tazobactam (79%, P = 0." | 3.88 | Empiric antibiotic protocols for cancer patients with neutropenia: a single-center study of treatment efficacy and mortality in patients with bacteremia. ( Cahan, A; Cohen, MJ; Kleinhendler, E; Moses, AE; Paltiel, O; Strahilevitz, J, 2018) |
| "To evaluate an existing once-daily gentamicin dosing guideline in children with febrile neutropenia resulting from antineoplastic therapy and, if necessary, to develop a new simulated dosing guideline that would achieve pharmacokinetic targets more reliably after the first dose." | 3.76 | Once-daily gentamicin dosing in children with febrile neutropenia resulting from antineoplastic therapy. ( Atenafu, EG; Boodhan, S; Dupuis, LL; Inparajah, M; Naqvi, A; Sibbald, C; Wong, C, 2010) |
| "We completed a study to determine if empiric use of gentamicin 7 mg/kg once daily in pediatric patients admitted with febrile neutropenia provided extrapolated peaks and drug-free intervals consistent with suggested preferred levels." | 3.75 | Assessment of gentamicin 7 mg/kg once daily for pediatric patients with febrile neutropenia: a pilot project. ( Lotocka-Reysner, H; Newby, B; Prevost, D, 2009) |
| " We explored the effects of neutropenia on the outcome of doxycycline and gentamicin therapy." | 3.74 | Comparison of 2 antibiotics that inhibit protein synthesis for the treatment of infection with Yersinia pestis delivered by aerosol in a mouse model of pneumonic plague. ( Bassett, J; Drusano, GL; Heine, HS; Kinzig-Schippers, M; Louie, A; Miller, L; Sorgel, F; Sullivan, LJ, 2007) |
| "OD gentamicin can be used safely and effectively to treat febrile neutropenia in children with cancer." | 3.70 | Once daily ceftriaxone and gentamicin for the treatment of febrile neutropenia. ( Das, S; Goodbourne, C; Lilleyman, JS; Price, C; Ronghe, M; Saha, V; Tomlinson, RJ, 1999) |
| "To determine the safety of single daily dose (SDD) gentamicin in recipients of stem cell transplantation (SCT), we evaluated all adult patients at MD Anderson Cancer Center who received SDD gentamicin for treatment of febrile neutropenia." | 3.70 | Toxicity of single daily dose gentamicin in stem cell transplantation. ( Bruton, J; Champlin, R; Ippoliti, C; Van Besien, K; Warkentin, D, 1999) |
| " Patients receiving gentamicin for febrile neutropenia may be considered pharmacokinetically similar to the general population receiving gentamicin." | 3.70 | Population analysis of once-daily dosing of gentamicin in patients with neutropenia. ( Duffull, SB; Peterson, AK, 1998) |
| "During a 12-month study, 42 adult patients with febrile neutropenia (granulocytes < 1 x 10(9)/l) were treated with once-daily gentamicin (5 mg/kg)." | 3.69 | Audit of once-daily dosing gentamicin therapy in neutropenic fever. ( Cooke, RP; Gover, PA; Grace, RJ, 1997) |
| "To report a case of ticlopidine-induced neutropenia resulting in Pseudomonas bacteremia." | 3.69 | Pseudomonas bacteremia precipitated by ticlopidine-induced neutropenia. ( Geletko, SM; Melbourne, KM; Mikolich, DJ, 1996) |
| "To minimize renal and hematological toxicity during empirical antibiotic therapy for pediatric patients with fever and neutropenia, piperacillin and gentamicin combination therapy was evaluated." | 3.67 | Piperacillin and gentamicin as non toxic empirical therapy in pediatric patients with fever and neutropenia. ( Clavell, LA; González, M, 1987) |
| "Patients with myelotoxic agranulocytosis were treated with gentamicin administered intravenously as drop-wise infusions in a dose of 5 mg/kg body weight a day every 8 hours." | 3.66 | [Gentamycin sulfate effectiveness and tolerance in patients with myelotoxic agranulocytosis]. ( Baranov, AE; Bodunkova, LE; Nadezhina, NM; Pozdniakova, VP; Shishkova, TV, 1979) |
| " The response rate to once-daily gentamicin dosing and azlocillin was three times higher than to multiple-daily gentamicin dosing and azlocillin (P = 0." | 2.69 | Once-daily versus multiple-daily gentamicin in empirical antibiotic therapy of febrile neutropenia following intensive chemotherapy. ( Bakri, FE; Duncombe, AS; Pallett, A; Smith, AG, 2000) |
| " Both regimens were combined with netilmicin i." | 2.69 | An open, randomized, multicentre study comparing the use of low-dose ceftazidime or cefotaxime, both in combination with netilmicin, in febrile neutropenic patients. German Multicentre Study Group. ( Fauser, AA; Finke, J; Höffken, G; Pasold, R; Pflüger, KH; Szelenyi, H; Wagner, J, 1999) |
| "Cefepime is an extended-spectrum fourth-generation cephalosporin that has good activity against gram-positive and gram-negative organisms; in addition, it resists degradation by Bush group 1 beta-lactamases." | 2.68 | Clinical experience with single agent and combination regimens in the management of infection in the febrile neutropenic patient. ( Cimino, M; Gucalp, R; Oblon, D; Ramphal, R; Rotstein, C, 1996) |
| "Isepamicin is a new aminoglycoside with in-vitro activity superior to amikacin." | 2.68 | Isepamicin once daily plus ceftriaxone versus amikacin plus ceftriaxone in febrile neutropenic patients. ( Blaise, D; Cordonnier, C; Espinouse, D; Herbrecht, R; Leblond, V; Minozzi, C; Sadoun, A; Sauvage, C, 1995) |
| "Cefepime was demonstrated to be an effective and safe treatment for febrile episodes in neutropenic patients with malignancies, and its lack of nephrotoxicity compared to P+G was noteworthy." | 2.68 | Open randomized study of cefepime versus piperacillin-gentamicin for treatment of febrile neutropenic cancer patients. ( Carlisle, P; Cimino, M; Gucalp, R; Roberts, J; Rotstein, C; Yamamura, D, 1997) |
| "A total of 107 febrile neutropenic cancer patients were randomly assigned to empiric therapy with ticarcillin-clavulanate (4 g ticarcillin + 0." | 2.68 | Randomized comparison between antibiotics alone and antibiotics plus granulocyte-macrophage colony-stimulating factor (Escherichia coli-derived in cancer patients with fever and neutropenia. ( Abi-Said, D; Anaissie, EJ; Bodey, GP; Kantarjian, H; Karl, C; Legrand, C; Vadhan-Raj, S; Vartivarian, S, 1996) |
| "There were five superinfections, all in the gentamicin/azlocillin group." | 2.67 | Randomized multicentre study of ciprofloxacin and azlocillin versus gentamicin and azlocillin in the treatment of febrile neutropenic patients. ( Barker, KF; Kaczmarski, RS; Mufti, GJ; Philpott-Howard, JN; Smedley, JC; Wade, JJ, 1990) |
| " Monotherapy with ceftazidime is as effective as when used in combination with an aminoglycoside in neutropenia." | 2.67 | Ceftazidime monotherapy is as effective as ceftazidime combined with gentamicin in the treatment of febrile neutropenic patients. ( Goldstone, AH; Kinsey, SE; Machin, SJ, 1990) |
| "Continuous infusions of gentamicin, amikacin or sisomicin combined with carbenicillin were compared in a randomized study in the treatment of 572 febrile episodes in 281 patients with cancer." | 2.65 | A randomized comparative trial of three aminoglycosides--comparison of continuous infusions of gentamicin, amikacin and sisomicin combined with carbenicillin in the treatment of infections in neutropenic patients with malignancies. ( Bodey, GP; Keating, MJ; Rodriguez, V; Valdivieso, M, 1979) |
| " Our guidelines include precise indications (severe sepsis, shock, drug resistance), dosing regimens (once-daily 20 mg/kg/day amikacin, 5 mg/kg/day gentamicin), durations of treatment, drug monitoring timing, and target C(max) concentrations (40 mg/l amikacin, 20 mg/l gentamicin)." | 1.38 | Therapeutic drug monitoring of aminoglycosides in acute myeloid leukaemia patients. ( Alfandari, S; Allorge, D; Berthon, C; Blondiaux, N; Cliquennois, E; Gay, J; Herbaux, C; Mareville, J; Pasquier, F, 2012) |
| " The infected animals received sc administrations of G-CSF, antibiotic or a combination of both agents at determined dosing regimens." | 1.31 | Modulation of efficacies and pharmacokinetics of antibiotics by granulocyte colony-stimulating factor in neutropenic mice with multidrug-resistant Enterococcus faecalis infection. ( Bow, L; Nicolau, DP; Nightingale, CH; Onyeji, CO, 2000) |
| "A total of 198 adult patients with cancer were included in the analysis." | 1.30 | Population pharmacokinetic parameters of gentamicin in patients with solid tumors: estimation by one- and two-stage methods. ( Aldaz, A; Brugarolas, A; Giráldez, J; Ortega, A, 1998) |
| " Results of additional analyses using hematologic or solid tumor subpopulations agree with those of a recent larger study which found no significant pharmacokinetic differences between these groups." | 1.29 | Nonparametric approach to population pharmacokinetics in oncology patients receiving aminoglycoside therapy. ( Batra, KK; Inciardi, JF, 1993) |
| " These results support the idea that the major significance of the PAE is in its application to dosing regimens." | 1.28 | In vivo postantibiotic effect of isepamicin and other aminoglycosides in a thigh infection model in neutropenic mice. ( Caminero, MM; Fuentes Martinez, F; Izquierdo Izquierdo, J; Minguez Minguez, F; Prieto Prieto, J, 1992) |
| " No pharmacokinetic differences were seen in half-life, volume of distribution (liter per kilogram; total and ideal body weight), or clearance (milliliter per minute per 1." | 1.28 | Gentamicin pharmacokinetics, nephrotoxicity, and prediction of mortality in febrile neutropenic patients. ( Bertino, JS; Bianco, TM; Dwyer, PN, 1989) |
| " Pharmacokinetic studies in mice showed a linear dose response in serum after the 20 and 50 mg/kg subcutaneous dose and urinary recoveries of administered dose of about 60% in 6 hours." | 1.28 | L-658,310, a new injectable cephalosporin. III. Experimental chemotherapeutics and pharmacokinetics in laboratory animals. ( Abruzzo, GK; Bland, JA; Fromtling, RA; Gadebusch, HH; Gilfillan, EC; Hadley, SK; Pelak, BA; Weissberger, BA, 1989) |
| "Gentamicin was administered to mice 2 h after intrabronchial challenge with 10(6) Pseudomonas to determine whether its effects were additive to immunization." | 1.27 | Pulmonary clearance of Pseudomonas aeruginosa in neutropenic mice. Effects of systemic immunization. ( Dunn, MM; Kamp, DW, 1987) |
| "Cefpiramide and cefoperazone alone and in combination with gentamicin were compared for therapeutic efficacy against pseudomonal infections in normal mice and in mice made neutropenic by administration of cyclophosphamide." | 1.27 | Therapeutic efficacy of cefpiramide and cefoperazone alone and in combination with gentamicin against pseudomonal infections in neutropenic mice. ( Fu, KP; Gregory, FJ; Hetzel, N; Hung, PP, 1986) |
| "Gentamicin in combination with cephalothin (Gent-Ceph) or with chloramphenicol (Gent-Chloro) was utilized in the treatment of 55 infections occurring in 49 cancer patients." | 1.26 | Therapy of infections in neutropenic patients: results with gentamicin in combination with cephalothin or chloramphenicol. ( Bodey, GP; Burgess, MA; Rodriguez, V; Valdivieso, M, 1976) |
| "Gentamicin was at least as effective as carbenicillin regardless of inoculum size or duration of therapy." | 1.26 | Therapy of neutropenic rats infected with Pseudomonas aeruginosa. ( Lumish, RM; Norden, CW, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 46 (39.66) | 18.7374 |
| 1990's | 42 (36.21) | 18.2507 |
| 2000's | 18 (15.52) | 29.6817 |
| 2010's | 10 (8.62) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kleinhendler, E | 1 |
| Cohen, MJ | 1 |
| Moses, AE | 1 |
| Paltiel, O | 1 |
| Strahilevitz, J | 1 |
| Cahan, A | 1 |
| Wuyts, L | 1 |
| Wojciechowski, M | 1 |
| Maes, P | 1 |
| Matthieu, L | 1 |
| Lambert, J | 1 |
| Aerts, O | 1 |
| Jent, P | 1 |
| Thalmann, L | 1 |
| Pabst, T | 1 |
| Droz, S | 1 |
| Sendi, P | 1 |
| Vinker-Shuster, M | 1 |
| Stepensky, P | 1 |
| Temper, V | 1 |
| Shayovitz, V | 1 |
| Masarwa, R | 1 |
| Averbuch, D | 1 |
| Doughty, CB | 1 |
| Cruz, AT | 1 |
| Kaplan, SL | 1 |
| Newby, B | 1 |
| Prevost, D | 1 |
| Lotocka-Reysner, H | 1 |
| Inparajah, M | 1 |
| Wong, C | 1 |
| Sibbald, C | 1 |
| Boodhan, S | 2 |
| Atenafu, EG | 1 |
| Naqvi, A | 1 |
| Dupuis, LL | 2 |
| Jang, HC | 1 |
| Lee, S | 1 |
| Song, KH | 1 |
| Jeon, JH | 1 |
| Park, WB | 1 |
| Park, SW | 1 |
| Kim, HB | 1 |
| Kim, NJ | 1 |
| Kim, EC | 1 |
| Oh, MD | 1 |
| Choe, KW | 1 |
| Zuluaga, AF | 1 |
| Agudelo, M | 1 |
| Cardeño, JJ | 1 |
| Rodriguez, CA | 1 |
| Vesga, O | 1 |
| Avent, ML | 1 |
| Teoh, J | 1 |
| Lees, J | 1 |
| Eckert, KA | 1 |
| Kirkpatrick, CM | 1 |
| Chen, J | 1 |
| Nanji, M | 1 |
| Chang, A | 1 |
| Sekharan, S | 1 |
| Lavoratore, S | 1 |
| Brandão, LR | 1 |
| Skolnik, JM | 1 |
| Mareville, J | 1 |
| Gay, J | 1 |
| Cliquennois, E | 1 |
| Herbaux, C | 1 |
| Pasquier, F | 1 |
| Allorge, D | 1 |
| Blondiaux, N | 1 |
| Berthon, C | 1 |
| Alfandari, S | 1 |
| Gorschlüter, M | 1 |
| Hahn, C | 1 |
| Fixson, A | 1 |
| Mey, U | 1 |
| Ziske, C | 1 |
| Molitor, E | 1 |
| Horré, R | 1 |
| Sauerbruch, T | 1 |
| Marklein, G | 2 |
| Schmidt-Wolf, IG | 1 |
| Glasmacher, A | 1 |
| Braunstein, A | 1 |
| Papo, N | 1 |
| Shai, Y | 1 |
| Yombi, JC | 1 |
| Wallemacq, P | 1 |
| Leal, T | 1 |
| Gala, JL | 1 |
| Vandercam, B | 1 |
| Ritchie, S | 1 |
| Palmer, S | 1 |
| Ellis-Pegler, R | 1 |
| Abbassi, MS | 1 |
| Achour, W | 1 |
| Hassen, AB | 1 |
| Barber, GR | 1 |
| Lauretta, J | 1 |
| Saez, R | 1 |
| Heine, HS | 1 |
| Louie, A | 1 |
| Sorgel, F | 1 |
| Bassett, J | 1 |
| Miller, L | 1 |
| Sullivan, LJ | 1 |
| Kinzig-Schippers, M | 1 |
| Drusano, GL | 1 |
| Laoprasopwattana, K | 1 |
| Pruekprasert, P | 1 |
| Laosombat, V | 1 |
| Wongchanchailert, M | 1 |
| Leahy, MF | 1 |
| Humble, MW | 1 |
| Meuret, G | 1 |
| Roux, A | 1 |
| Heim, ME | 1 |
| Westerhausen, M | 1 |
| Malarme, M | 1 |
| Meunier-Carpentier, F | 1 |
| Klastersky, J | 4 |
| Magliulo, E | 1 |
| Piantieri, G | 1 |
| Cafarelli, A | 1 |
| Cruciani, M | 1 |
| Young, LS | 1 |
| Meyer-Dudnik, PV | 1 |
| Hindler, J | 1 |
| Martin, WJ | 1 |
| Baranov, AE | 2 |
| Petrosian, LN | 1 |
| Nadezhina, NM | 2 |
| Shishkova, TV | 2 |
| Nesterova, VI | 1 |
| MacGowan, AP | 1 |
| Bedford, KA | 1 |
| Blundell, E | 1 |
| Brown, NM | 1 |
| Habib, F | 1 |
| Hows, J | 1 |
| Kirkpatrick, B | 1 |
| Korner, RJ | 1 |
| Slade, RR | 1 |
| White, LO | 1 |
| Au, E | 1 |
| Tow, A | 1 |
| Allen, DM | 1 |
| Ang, PT | 1 |
| Pea, F | 1 |
| Miglioli, PA | 1 |
| Mazzo, M | 1 |
| Berti, T | 1 |
| Inciardi, JF | 1 |
| Batra, KK | 1 |
| Studená, M | 1 |
| Hlavácová, E | 1 |
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4 reviews available for gentamicin and Neutropenia
| Article | Year |
|---|---|
Juvenile ecthyma gangrenosum caused by Pseudomonas aeruginosa revealing an underlying neutropenia: case report and review of the literature.
Topics: Anti-Bacterial Agents; Ecthyma; Female; Gangrene; Gentamicins; Granulocyte Colony-Stimulating Factor | 2019 |
[Cefepim in febrile neutropenic patients].
Topics: Adult; Cefepime; Cephalosporins; Child; Fever; Gentamicins; Humans; Neutropenia; Penicillins; Pipera | 1998 |
The use of synergistic combinations of antibiotics in patients with haematological diseases.
Topics: Agranulocytosis; Ampicillin; Animals; Anti-Bacterial Agents; Bacterial Infections; Blood Bactericida | 1976 |
[Management of infections in neutropenia].
Topics: Agranulocytosis; Bacterial Infections; Carbenicillin; Cross Infection; Gentamicins; Humans; Immunity | 1974 |
42 trials available for gentamicin and Neutropenia
| Article | Year |
|---|---|
Gram-negative Bacteremia in Children With Hematologic Malignancies and Following Hematopoietic Stem Cell Transplantation: Epidemiology, Resistance, and Outcome.
Topics: Adolescent; Allografts; Bacteremia; Child; Child, Preschool; Drug Combinations; Drug Resistance, Bac | 2019 |
A reliable and safe method of collecting blood samples from implantable central venous catheters for determination of plasma gentamicin concentrations.
Topics: Adolescent; Anti-Bacterial Agents; Blood Specimen Collection; Catheterization, Central Venous; Child | 2011 |
Piperacillin-tazobactam is more effective than ceftriaxone plus gentamicin in febrile neutropenic patients with hematological malignancies: a randomized comparison.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ceftriaxone; Cost-Benefit Analysi | 2003 |
Key pharmacokinetic parameters of isepamicin in febrile neutropenic cancer patients and in women with acute pelvic inflammatory disease.
Topics: Acute Disease; Adult; Anti-Bacterial Agents; Area Under Curve; Female; Fever; Gentamicins; Hematolog | 2005 |
Clinical outcome of febrile neutropenia in children with cancer using ceftazidime and aminoglycosides.
Topics: Adolescent; Amikacin; Anti-Bacterial Agents; Bacteremia; Ceftazidime; Child; Child, Preschool; Disea | 2007 |
[Treatment of severe febrile neutropenia (author's transl)].
Topics: Agranulocytosis; Carbenicillin; Drug Evaluation; Drug Therapy, Combination; Fever; Gentamicins; Huma | 1980 |
Vancomycin plus gentamicin and cotrimoxazole for prevention of infections in neutropenic cancer patients (a comparative, placebo-controlled pilot study).
Topics: Adult; Agranulocytosis; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Clinical | 1981 |
Aminoglycosides in the treatment of bacteraemic infections in the immuno-comprised host.
Topics: Agranulocytosis; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Drug Therapy, Combination; Gentam | 1981 |
Randomised study comparing imipenem/cilastatin to ceftriaxone plus gentamicin in cancer chemotherapy-induced neutropenic fever.
Topics: Antineoplastic Agents; Ceftriaxone; Cilastatin; Cilastatin, Imipenem Drug Combination; Costs and Cos | 1994 |
Once-daily pefloxacin + teicoplanin vs netilmicin + teicoplanin in empirical therapy for fever and neutropenia.
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Drug Therapy, Combination; Female; Fever; Genta | 1995 |
Randomized comparison between antibiotics alone and antibiotics plus granulocyte-macrophage colony-stimulating factor (Escherichia coli-derived in cancer patients with fever and neutropenia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; beta-Lactamase Inhibitors; Clavul | 1996 |
Isepamicin once daily plus ceftriaxone versus amikacin plus ceftriaxone in febrile neutropenic patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Bone Marrow Transplanta | 1995 |
Clinical experience with single agent and combination regimens in the management of infection in the febrile neutropenic patient.
Topics: Anti-Bacterial Agents; Cefepime; Ceftazidime; Cephalosporins; Drug Therapy, Combination; Female; Fev | 1996 |
Randomized trial comparing netilmicin plus imipenem-cilastatin versus netilmicin plus ceftazidime as empiric therapy for febrile neutropenic bone marrow transplant recipients.
Topics: Adolescent; Adult; Bacteria; Bacterial Infections; Bone Marrow Transplantation; Ceftazidime; Cephalo | 1997 |
Open randomized study of cefepime versus piperacillin-gentamicin for treatment of febrile neutropenic cancer patients.
Topics: Adult; Bacterial Infections; Cefepime; Cephalosporins; Drug Therapy, Combination; Female; Fever; Gen | 1997 |
Ciprofloxacin plus piperacillin is an equally effective regimen for empiric therapy in febrile neutropenic patients compared with standard therapy.
Topics: Adult; Amphotericin B; Bacterial Infections; Ciprofloxacin; Drug Therapy, Combination; Female; Fever | 1998 |
An open, randomized, multicentre study comparing the use of low-dose ceftazidime or cefotaxime, both in combination with netilmicin, in febrile neutropenic patients. German Multicentre Study Group.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cefotaxime; | 1999 |
Once-daily versus multiple-daily gentamicin in empirical antibiotic therapy of febrile neutropenia following intensive chemotherapy.
Topics: Adult; Aged; Anti-Bacterial Agents; Antineoplastic Agents; Azlocillin; Bacterial Infections; Female; | 2000 |
Piperacillin, beta-lactam inhibitor plus gentamicin as empirical therapy of a sequential regimen in febrile neutropenia of pediatric cancer patients.
Topics: Adolescent; Anti-Bacterial Agents; Bacterial Infections; Child; Drug Therapy, Combination; Enzyme In | 2001 |
Comparison of isepamicin with amikacin for the empirical treatment of febrile neutropenic children with malignancies.
Topics: Amikacin; Anti-Bacterial Agents; Bacterial Infections; Child; Child, Preschool; Drug-Related Side Ef | 2001 |
A randomized monocentric trial in febrile neutropenic patients: ceftriaxone and gentamicin vs cefepime and gentamicin.
Topics: Anti-Bacterial Agents; Cefepime; Ceftriaxone; Cephalosporins; Drug Therapy, Combination; Fever; Gent | 2002 |
A study of antibiotic therapy in fever of unknown origin in neutropenic cancer patients.
Topics: Adult; Aged; Agranulocytosis; Anti-Bacterial Agents; Carbenicillin; Cephalothin; Chloramphenicol; Cl | 1977 |
A randomized comparative trial of three aminoglycosides--comparison of continuous infusions of gentamicin, amikacin and sisomicin combined with carbenicillin in the treatment of infections in neutropenic patients with malignancies.
Topics: Adolescent; Adult; Aged; Amikacin; Bacterial Infections; Carbenicillin; Drug Therapy, Combination; F | 1979 |
Protocol for an international prospective trial of initial therapy regimens in neutropenic patients with malignant disease.
Topics: Agranulocytosis; Bacterial Infections; Blood; Carbenicillin; Cephalothin; Clinical Trials as Topic; | 1975 |
Prospective randomly controlled trial of three antibiotic combinations for empirical therapy of suspected sepsis in neutropenic cancer patients.
Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Cephalothin; Clinical Trials as Topic; | 1975 |
A comparative study of imipenem versus piperacillin plus gentamicin in the initial management of febrile neutropenic patients with haematological malignancies.
Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Fever; Gentamicins; Humans; Imipenem; Leukemia; | 1992 |
Piperacillin/tazobactam plus gentamicin as empirical therapy for febrile neutropenic patients with haematological malignancy.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bacterial Infections; beta-Lactamase Inhibitors; Bon | 1992 |
Teicoplanin plus ciprofloxacin versus gentamicin plus piperacillin in the treatment of febrile neutropenic patients.
Topics: Bacterial Infections; Ciprofloxacin; Drug Therapy, Combination; Fever; Gentamicins; Glycopeptides; H | 1992 |
[Aztreonam or gentamicin combined with piperacillin as empiric antibiotic therapy during neutropenia of patients with hematologic diseases].
Topics: Adolescent; Adult; Aged; Anemia, Aplastic; Aztreonam; Bacterial Infections; Cefamandole; Drug Therap | 1992 |
Imipenem versus gentamicin combined with either cefuroxime or cephalothin as initial therapy for febrile neutropenic patients.
Topics: Adult; Aged; Cefuroxime; Cephalothin; Drug Therapy, Combination; Female; Gentamicins; Humans; Imipen | 1992 |
Aztreonam plus vancomycin versus gentamicin plus piperacillin as empirical therapy for the treatment of fever in neutropenic patients: a randomised controlled study.
Topics: Adult; Aztreonam; Bacteremia; Drug Therapy, Combination; Fever; Gentamicins; Gram-Negative Bacteria; | 1992 |
Aztreonam therapy in children with febrile neutropenia: a randomized trial of aztreonam plus flucloxacillin versus piperacillin plus gentamicin.
Topics: Adolescent; Aztreonam; Bacteremia; Child; Child, Preschool; Drug Therapy, Combination; Female; Fever | 1991 |
Pefloxacin and vancomycin vs. gentamicin, colistin sulphate and vancomycin for prevention of infections in granulocytopenic patients: a randomised double-blind study.
Topics: Adult; Aged; Antineoplastic Agents; Bacterial Infections; Colistin; Double-Blind Method; Drug Therap | 1991 |
Ceftazidime monotherapy is as effective as ceftazidime combined with gentamicin in the treatment of febrile neutropenic patients.
Topics: Agranulocytosis; Anti-Bacterial Agents; Cause of Death; Ceftazidime; Drug Therapy, Combination; Fema | 1990 |
A randomized study of teicoplanin plus ciprofloxacin versus gentamicin plus piperacillin for the empirical treatment of fever in neutropenic patients.
Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bone Marrow Transplantation; Ciprofloxacin; D | 1990 |
Teicoplanin compared to flucloxacillin for antibiotic treatment of neutropenic patients.
Topics: Anti-Bacterial Agents; Bacteria; Bone Marrow Transplantation; Drug Therapy, Combination; Fever; Flox | 1990 |
Randomized multicentre study of ciprofloxacin and azlocillin versus gentamicin and azlocillin in the treatment of febrile neutropenic patients.
Topics: Adolescent; Adult; Azlocillin; Bacterial Infections; Ciprofloxacin; Drug Therapy, Combination; Femal | 1990 |
Gentamicin and low dose piperacillin in febrile neutropenic patients.
Topics: Adult; Agranulocytosis; Bacterial Infections; Fever; Gentamicins; Humans; Injections, Intravenous; L | 1989 |
Ceftazidime with or without vancomycin vs. cephalothin, carbenicillin and gentamicin as the initial therapy of the febrile neutropenic pediatric cancer patient.
Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Carbenicillin; Ceftazidime; Cephalothi | 1988 |
A randomized trial comparing ceftazidime alone with combination antibiotic therapy in cancer patients with fever and neutropenia.
Topics: Adolescent; Adult; Aged; Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Carbenicillin | 1986 |
A randomized trial of oral vancomycin in neutropenic patients.
Topics: Administration, Oral; Adolescent; Adult; Aged; Agranulocytosis; Antineoplastic Agents; Clinical Tria | 1985 |
Review of amikacin usage in the EORTC trials.
Topics: Agranulocytosis; Amikacin; Anti-Bacterial Agents; Bacterial Infections; Clinical Trials as Topic; Dr | 1985 |
70 other studies available for gentamicin and Neutropenia
| Article | Year |
|---|---|
Empiric antibiotic protocols for cancer patients with neutropenia: a single-center study of treatment efficacy and mortality in patients with bacteremia.
Topics: Adult; Anti-Bacterial Agents; Bacteremia; Blood Culture; Carbapenem-Resistant Enterobacteriaceae; Ce | 2018 |
Adjunctive gentamicin did not improve outcome of enterococcal bacteraemia in neutropenic patients: a propensity scored matched study.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteremia; Cross Infection; Drug Resistance, Bacterial; Drug Th | 2019 |
A bullous lesion in a neutropenic adolescent.
Topics: Adolescent; Blister; Clavulanic Acid; Drug Therapy, Combination; Gentamicins; Humans; Immunocompromi | 2009 |
Assessment of gentamicin 7 mg/kg once daily for pediatric patients with febrile neutropenia: a pilot project.
Topics: Adolescent; Anti-Infective Agents; Candidiasis; Child; Child, Preschool; Creatinine; Female; Fever; | 2009 |
Once-daily gentamicin dosing in children with febrile neutropenia resulting from antineoplastic therapy.
Topics: Adolescent; Aging; Anti-Bacterial Agents; Antineoplastic Agents; Body Weight; Child; Child, Preschoo | 2010 |
Clinical features, risk factors and outcomes of bacteremia due to enterococci with high-level gentamicin resistance: comparison with bacteremia due to enterococci without high-level gentamicin resistance.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteremia; Cephalosporins; Cross Infection; Drug Re | 2010 |
Determination of therapeutic equivalence of generic products of gentamicin in the neutropenic mouse thigh infection model.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Disease Models, Animal; Drugs, Generic; Gentam | 2010 |
Comparing 3 methods of monitoring gentamicin concentrations in patients with febrile neutropenia.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Area Under Curve; Dose-Response Relationship, Drug; | 2011 |
Therapeutic drug monitoring of aminoglycosides in acute myeloid leukaemia patients.
Topics: Adult; Aged; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Drug Administra | 2012 |
In vitro activity and potency of an intravenously injected antimicrobial peptide and its DL amino acid analog in mice infected with bacteria.
Topics: Acinetobacter baumannii; Acinetobacter Infections; Amino Acids; Animals; Anti-Bacterial Agents; Bact | 2004 |
High-risk febrile neutropenia in Auckland 2003-2004: the influence of the microbiology laboratory on patient treatment and the use of pathogen-specific therapy.
Topics: Anti-Bacterial Agents; Bacteremia; Bacteria; Bacterial Infections; Catheterization; Cefepime; Cephal | 2007 |
High-level gentamicin-resistant Enterococcus faecium strains isolated from bone marrow transplant patients: accumulation of antibiotic resistance genes, large plasmids and clonal strain dissemination.
Topics: Anti-Bacterial Agents; Bone Marrow Transplantation; DNA, Bacterial; Drug Resistance, Bacterial; Elec | 2007 |
A febrile neutropenic patient with Enterococcus gallinarum sepsis treated with daptomycin and gentamicin.
Topics: Anti-Bacterial Agents; Bacteremia; Catheters, Indwelling; Cross Infection; Daptomycin; Drug Resistan | 2007 |
Comparison of 2 antibiotics that inhibit protein synthesis for the treatment of infection with Yersinia pestis delivered by aerosol in a mouse model of pneumonic plague.
Topics: Aerosols; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Doxycycline; Female; Gen | 2007 |
Outbreak of co-trimoxazole- and gentamicin-resistant Klebsiella aerogenes bacteremia in neutropenic patients receiving oral co-trimoxazole prophylaxis.
Topics: Aged; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Gentamicins; | 1983 |
Therapy of Klebsiella pneumoniae septicaemia in neutropenic rats.
Topics: Agranulocytosis; Amikacin; Animals; Anti-Bacterial Agents; Female; Gentamicins; Klebsiella Infection | 1982 |
[Use of patient isolation, nonabsorbable antibiotics and intravenous administration of gentamycin for prevention of infectious complications in hemoblastoses during cytostatic therapy].
Topics: Acute Disease; Administration, Oral; Adult; Anti-Bacterial Agents; Antineoplastic Agents; Bacterial | 1981 |
The pharmacokinetics of once daily gentamicin in neutropenic adults with haematological malignancy.
Topics: Adolescent; Adult; Aged; Azlocillin; Female; Gentamicins; Humans; Leukemia; Lymphoma; Male; Middle A | 1994 |
Study on the bactericidal activity and synergistic effect of neutropenic rat serum with gentamicin.
Topics: Animals; Blood Bactericidal Activity; Blood Physiological Phenomena; Cyclophosphamide; Escherichia c | 1994 |
Nonparametric approach to population pharmacokinetics in oncology patients receiving aminoglycoside therapy.
Topics: Adult; Aged; Algorithms; Anti-Bacterial Agents; Female; Gentamicins; Humans; Male; Middle Aged; Neop | 1993 |
Single or multiple daily doses of aminoglycosides. Giving gentamicin once daily for neutropenic fever has proved to be simple.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Fever; Gentamicins; Humans; Middl | 1996 |
Pseudomonas bacteremia precipitated by ticlopidine-induced neutropenia.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacteremia; Ceftazidime; Cephalosporins; Filgrastim; | 1996 |
Antibiotic prophylaxis in gastrointestinal endoscopy: a report by a Working Party for the British Society of Gastroenterology Endoscopy Committee.
Topics: Administration, Oral; Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophyla | 1997 |
Audit of once-daily dosing gentamicin therapy in neutropenic fever.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bone Marrow Diseases; Drug Admini | 1997 |
Population pharmacokinetic parameters of gentamicin in patients with solid tumors: estimation by one- and two-stage methods.
Topics: Adult; Aged; Analysis of Variance; Anti-Bacterial Agents; Cohort Studies; Drug Monitoring; Female; F | 1998 |
Ototoxicity induced by once-daily gentamicin.
Topics: Adult; Anti-Bacterial Agents; Drug Administration Schedule; Female; Fever of Unknown Origin; Gentami | 1998 |
Population analysis of once-daily dosing of gentamicin in patients with neutropenia.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Admini | 1998 |
Once daily ceftriaxone and gentamicin for the treatment of febrile neutropenia.
Topics: Adolescent; Ceftriaxone; Child; Child, Preschool; Drug Administration Schedule; Drug Therapy, Combin | 1999 |
Toxicity of single daily dose gentamicin in stem cell transplantation.
Topics: Adult; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gentamicin | 1999 |
Modulation of efficacies and pharmacokinetics of antibiotics by granulocyte colony-stimulating factor in neutropenic mice with multidrug-resistant Enterococcus faecalis infection.
Topics: Animals; Anti-Bacterial Agents; Drug Resistance, Multiple; Drug Therapy, Combination; Enterococcus f | 2000 |
Prediction of gram-negative bacteremia in patients with cancer and febrile neutropenia by means of interleukin-8 levels in serum: targeting empirical monotherapy versus combination therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacteremia; Cefepime; Cephalosporins; Drug Therapy, Comb | 2001 |
Effects of adjunctive treatment with combined cytokines in a neutropenic mouse model of multidrug-resistant Enterococcus faecalis septicemia.
Topics: Animals; Anti-Bacterial Agents; Cytokines; Drug Resistance, Multiple; Drug Therapy, Combination; Ent | 2001 |
Usefulness of bronchoalveolar lavage for the diagnosis and treatment of refractory pneumonia in a patient with Kostmann syndrome, a severe congenital neutropenia.
Topics: Bronchoalveolar Lavage; Child; Female; Gentamicins; Humans; Neutropenia; Pneumonia, Bacterial; Pseud | 2001 |
Neutropenia, fever, and infection in children with acute lymphocytic leukemia.
Topics: Agranulocytosis; Asparaginase; Child; Fever; Gentamicins; Granulocytes; Humans; Infections; Leukemia | 1977 |
Surveillance of nosocomial infections by antibiotic monitoring.
Topics: Anti-Bacterial Agents; Cross Infection; Epidemiologic Methods; Fever of Unknown Origin; Gentamicins; | 1979 |
[Gentamycin sulfate effectiveness and tolerance in patients with myelotoxic agranulocytosis].
Topics: Agranulocytosis; Drug Evaluation; Drug Therapy, Combination; Drug Tolerance; Evaluation Studies as T | 1979 |
Possible high dosage gentamycin therapy in infected neutropenic patients.
Topics: Agranulocytosis; Ampicillin; Drug Therapy, Combination; Gentamicins; Humans; Infections; Neutropenia | 1977 |
Therapy of infections in neutropenic patients: results with gentamicin in combination with cephalothin or chloramphenicol.
Topics: Agranulocytosis; Bacterial Infections; Cephalothin; Chloramphenicol; Drug Therapy, Combination; Ente | 1976 |
Successful treatment of Pseudomonas meningitis and septicemia in a leukemic neutropenic adult.
Topics: Adult; Carbenicillin; Female; Gentamicins; Humans; Injections, Intravenous; Injections, Spinal; Leuk | 1975 |
Therapy of neutropenic rats infected with Pseudomonas aeruginosa.
Topics: Agranulocytosis; Animals; Blood; Carbenicillin; Female; Gentamicins; Microbial Sensitivity Tests; Ne | 1976 |
Synergistic activity of carbenicillin and gentamicin in experimental Pseudomonas bacteremia in neutropenic rats.
Topics: Agranulocytosis; Animals; Carbenicillin; Drug Synergism; Female; Gentamicins; Neutropenia; Pseudomon | 1976 |
Neutropenia and salmonellosis in hospitalized horses.
Topics: Agranulocytosis; Animals; Chloramphenicol; Colitis; Feces; Female; Gentamicins; Horse Diseases; Hors | 1975 |
[Combination effect of KW-2228 and aminoglycoside antibiotics on systemic infection in cyclophosphamide-treated tumor-bearing mice].
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Cyclophosphamide; Drug Therapy, Combination; Gentam | 1992 |
Neutropenic sepsis complicating treatment of solid tumours, lymphoma and myeloma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Cefuroxime; Drug Therapy, Comb | 1992 |
In vivo postantibiotic effect of isepamicin and other aminoglycosides in a thigh infection model in neutropenic mice.
Topics: Animals; Bacterial Infections; Disease Models, Animal; Escherichia coli; Female; Gentamicins; Mice; | 1992 |
Clinical evaluation of ticarcillin, with clavulanic acid, and gentamicin in the treatment of febrile episodes in neutropenic children.
Topics: Child; Child, Preschool; Clavulanic Acids; Drug Resistance, Microbial; Drug Therapy, Combination; Fe | 1991 |
Chemotherapy-induced neutropenia and fever in patients receiving cisplatin-based chemotherapy for ovarian malignancy.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Cisplatin; Drug Therapy | 1991 |
Further characterization of monoclonal antibodies to lipopolysaccharide of Salmonella Minnesota strain R595.
Topics: Animals; Antibodies, Bacterial; Antibodies, Monoclonal; Antibody Specificity; Cross Reactions; Esche | 1990 |
Survival after intramuscular or inhalation administration of gentamicin in neutropenic guinea pigs infected by Klebsiella pneumoniae.
Topics: Administration, Inhalation; Aerosols; Animals; Gentamicins; Guinea Pigs; Injections, Intramuscular; | 1990 |
Effect of ceftazidime and gentamicin on the oropharyngeal and faecal flora of patients with haematological malignancies.
Topics: Ceftazidime; Colistin; Enterobacter; Feces; Gentamicins; Humans; Leukemia, Myeloid, Acute; Lymphoma, | 1990 |
Gentamicin pharmacokinetics, nephrotoxicity, and prediction of mortality in febrile neutropenic patients.
Topics: Agranulocytosis; Creatinine; Female; Fever; Gentamicins; Half-Life; Humans; Kidney Diseases; Male; M | 1989 |
L-658,310, a new injectable cephalosporin. III. Experimental chemotherapeutics and pharmacokinetics in laboratory animals.
Topics: Animals; Bacterial Infections; Ceftazidime; Cephalosporins; Diabetes Mellitus, Experimental; Drug Re | 1989 |
[Empirical antimicrobial therapy of infection and fever episodes in children and adolescents with neutropenia caused by cytotoxic chemotherapy].
Topics: Adolescent; Agranulocytosis; Antineoplastic Agents; Cefamandole; Cefotaxime; Child; Child, Preschool | 1989 |
Synergy of ciprofloxacin and azlocillin in vitro and in a neutropenic mouse model of infection.
Topics: Animals; Azlocillin; Bacteria; Carbenicillin; Ciprofloxacin; Drug Synergism; Drug Therapy, Combinati | 1986 |
Pulmonary clearance of Pseudomonas aeruginosa in neutropenic mice. Effects of systemic immunization.
Topics: Agranulocytosis; Animals; Antibodies, Anti-Idiotypic; Gentamicins; Immunization, Passive; Immunoglob | 1987 |
In vivo and in vitro activity of ciprofloxacin plus azlocillin against 12 streptococcal isolates in a neutropenic site model.
Topics: Amikacin; Animals; Azlocillin; Ciprofloxacin; Disease Models, Animal; Drug Synergism; Drug Therapy, | 1987 |
Bacteremia in neutropenic patients at a major teaching hospital--1981 to 1987.
Topics: Agranulocytosis; Amikacin; Australia; Cefotaxime; Drug Therapy, Combination; Gentamicins; Hospitals, | 1988 |
Comparative efficacy of ciprofloxacin, ceftazidime and gentamicin, given alone or in combination, in a model of experimental septicemia due to Klebsiella pneumoniae in neutropenic mice.
Topics: Agranulocytosis; Animals; Ceftazidime; Ciprofloxacin; Disease Models, Animal; Drug Therapy, Combinat | 1988 |
Comparative efficacy of different beta-lactam antibiotics and gentamicin in Klebsiella pneumoniae septicaemia in neutropenic mice.
Topics: Animals; Anti-Bacterial Agents; beta-Lactamases; beta-Lactams; Gentamicins; Klebsiella Infections; K | 1986 |
Piperacillin and gentamicin as non toxic empirical therapy in pediatric patients with fever and neutropenia.
Topics: Adolescent; Agranulocytosis; Bacterial Infections; Child; Child, Preschool; Drug Administration Sche | 1987 |
Therapeutic efficacy of cefpiramide and cefoperazone alone and in combination with gentamicin against pseudomonal infections in neutropenic mice.
Topics: Animals; Cefoperazone; Cephalosporins; Cyclophosphamide; Drug Combinations; Drug Evaluation, Preclin | 1986 |
Synergistic activity of apalcillin and gentamicin in a combination therapy in experimental Pseudomonas bacteraemia of neutropenic mice.
Topics: Ampicillin; Animals; Drug Synergism; Drug Therapy, Combination; Female; Gentamicins; Mice; Microbial | 1986 |
In vitro models for the study of combination antibiotic therapy in neutropenic patients.
Topics: Agranulocytosis; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Azlocillin; Bacterial Infections; | 1986 |
Forecast of antibiotic susceptibility of translocating strains of enterobacteria and pseudomonas in leukemic neutropenic patients.
Topics: Agranulocytosis; Amikacin; Ampicillin; Anti-Bacterial Agents; Cefotaxime; Enterobacteriaceae; Feces; | 1985 |
Bacteremia due to Pseudomonas aeruginosa complicating neoplastic disease: a progress report.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Bacteriological Techniques; Carbenicillin; Child; Ch | 1974 |
Indications for systemic antibiotic prophylaxis in neutropenic patients.
Topics: Adult; Agranulocytosis; Anti-Bacterial Agents; Biguanides; Blood Cell Count; Carbenicillin; Cephalot | 1974 |
Changing patterns of infection in cancer patients.
Topics: Bacterial Infections; Carbenicillin; Cephalothin; Clindamycin; Drug Therapy, Combination; Escherichi | 1973 |
Letter: Pseudomonas septicaemia following superficial colonization.
Topics: Adolescent; Agranulocytosis; Carbenicillin; Child; Gentamicins; Humans; Male; Neutropenia; Pseudomon | 1974 |
Empirical antibiotic therapy in febrile patients with neutropenia and malignant disease.
Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Carbenicillin; Cephalothin; Clindamyci | 1973 |
Advances in the management of Pseudomonas aeruginosa infections in cancer patients.
Topics: Carbenicillin; Colistin; Ecthyma; Gentamicins; Humans; Leukemia; Leukemia, Lymphoid; Lymphoma; Menin | 1973 |