gentamicin has been researched along with Muscular Dystrophies, Limb-Girdle in 1 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Muscular Dystrophies, Limb-Girdle: A heterogenous group of inherited muscular dystrophy that can be autosomal dominant or autosomal recessive. There are many forms (called LGMDs) involving genes encoding muscle membrane proteins such as the sarcoglycan (SARCOGLYCANS) complex that interacts with DYSTROPHIN. The disease is characterized by progressing wasting and weakness of the proximal muscles of arms and legs around the HIPS and SHOULDERS (the pelvic and shoulder girdles).
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this case report of a woman in her 30s with EBS-MD, before gentamicin treatment, the patient had mucocutaneous involvement, skeletal and respiratory muscle weakness, and myalgia that negatively affected her quality of life." | 8.12 | Evaluation of Systemic Gentamicin as Translational Readthrough Therapy for a Patient With Epidermolysis Bullosa Simplex With Muscular Dystrophy Owing to PLEC1 Pathogenic Nonsense Variants. ( de Arriba, MDC; de Lucas, R; Del Río, M; Duarte, B; Escámez, MJ; Esteban-Rodríguez, I; García, M; Guerrero-Aspizúa, S; Hernández-Fernández, CP; Illera, N; Larcher, F; Martínez-Santamaría, L; Mascías, J; Maseda, R; Membrilla, JA; Quintana, L; Sigüenza, AI; Woodley, DT, 2022) |
| "In this case report of a woman in her 30s with EBS-MD, before gentamicin treatment, the patient had mucocutaneous involvement, skeletal and respiratory muscle weakness, and myalgia that negatively affected her quality of life." | 4.12 | Evaluation of Systemic Gentamicin as Translational Readthrough Therapy for a Patient With Epidermolysis Bullosa Simplex With Muscular Dystrophy Owing to PLEC1 Pathogenic Nonsense Variants. ( de Arriba, MDC; de Lucas, R; Del Río, M; Duarte, B; Escámez, MJ; Esteban-Rodríguez, I; García, M; Guerrero-Aspizúa, S; Hernández-Fernández, CP; Illera, N; Larcher, F; Martínez-Santamaría, L; Mascías, J; Maseda, R; Membrilla, JA; Quintana, L; Sigüenza, AI; Woodley, DT, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Martínez-Santamaría, L | 1 |
| Maseda, R | 1 |
| de Arriba, MDC | 1 |
| Membrilla, JA | 1 |
| Sigüenza, AI | 1 |
| Mascías, J | 1 |
| García, M | 1 |
| Quintana, L | 1 |
| Esteban-Rodríguez, I | 1 |
| Hernández-Fernández, CP | 1 |
| Illera, N | 1 |
| Duarte, B | 1 |
| Guerrero-Aspizúa, S | 1 |
| Woodley, DT | 1 |
| Del Río, M | 1 |
| de Lucas, R | 1 |
| Larcher, F | 1 |
| Escámez, MJ | 1 |
1 other study available for gentamicin and Muscular Dystrophies, Limb-Girdle
| Article | Year |
|---|---|
Evaluation of Systemic Gentamicin as Translational Readthrough Therapy for a Patient With Epidermolysis Bullosa Simplex With Muscular Dystrophy Owing to PLEC1 Pathogenic Nonsense Variants.
Topics: Epidermolysis Bullosa Simplex; Female; Gentamicins; Humans; Muscular Dystrophies; Muscular Dystrophi | 2022 |