gentamicin has been researched along with Muscular Atrophy, Spinal in 2 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Muscular Atrophy, Spinal: A group of disorders marked by progressive degeneration of motor neurons in the spinal cord resulting in weakness and muscular atrophy, usually without evidence of injury to the corticospinal tracts. Diseases in this category include Werdnig-Hoffmann disease and later onset SPINAL MUSCULAR ATROPHIES OF CHILDHOOD, most of which are hereditary. (Adams et al., Principles of Neurology, 6th ed, p1089)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Many have neonatal phenotypes." | 1.42 | ECG in neonate mice with spinal muscular atrophy allows assessment of drug efficacy. ( DiDonato, CJ; Heier, CR, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Heier, CR | 2 |
| DiDonato, CJ | 2 |
2 other studies available for gentamicin and Muscular Atrophy, Spinal
| Article | Year |
|---|---|
ECG in neonate mice with spinal muscular atrophy allows assessment of drug efficacy.
Topics: Animals; Animals, Newborn; Biomarkers; Bradycardia; Disease Models, Animal; Drug Evaluation, Preclin | 2015 |
Translational readthrough by the aminoglycoside geneticin (G418) modulates SMN stability in vitro and improves motor function in SMA mice in vivo.
Topics: Aminoglycosides; Animals; Base Sequence; Cell Line; Codon, Terminator; Exons; Fibroblasts; Gentamici | 2009 |