gentamicin has been researched along with Muscle Contraction in 40 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Neostigmine and calcium antagonized the neuromuscular blockade caused by gentamicin, but augmented that caused by clindamycin." | 3.74 | Calcium and neostigmine antagonize gentamicin, but augment clindamycin-induced tetanic fade in rat phrenic nerve-hemidiaphragm preparations. ( Lee, JH; Lee, JM; Lee, SC; Lee, SI, 2008) |
| "5 mM), gentamicin (4 mM), and hypoxia; altered inotropic reactivity to these interventions followed similar temporal development as the postendotoxin changes in basal contractile parameters." | 3.67 | Development of myocardial dysfunction in endotoxin shock. ( Adams, HR; Parker, JL, 1985) |
| "Succinylcholine (1 mg/kg) was administered after induction of anesthesia and the magnitude and duration of neuromuscular block monitored." | 2.65 | Neuromuscular blocking effects of tobramycin, gentamicin, and cefazolin. ( Au, E; Lee, C; Lippmann, M; Yang, E, 1982) |
| "Gentamicin is an aminoglycoside antibiotic that is very effective in treating different gram negative infections, however, one of its main side effects is nephrotoxicity." | 1.33 | Resveratrol inhibits gentamicin-induced mesangial cell contraction. ( López-Novoa, JM; Mayoral, P; Morales, AI; Pérez-Barriocanal, F; Rodríguez-Barbero, A; Vicente-Sánchez, C, 2006) |
| " Cumulative drug dose-response curves were obtained for three different muscles in 24 rabbits." | 1.31 | Neuromuscular blocking effects of the aminoglycoside antibiotics arbekacin, astromicin, isepamicin and netilmicin on the diaphragm and limb muscles in the rabbit. ( Hashimoto, Y; Kato, M; Liu, M, 2001) |
| "Gentamicin did not cause a decrease in initial muscular strength, nor did it impair the muscles' ability to sustain strength." | 1.30 | Effects of high-dose gentamicin sulfate on neuromuscular blockade in halothane-anesthetized horses. ( Hague, BA; Hartsfield, SM; Martinez, EA, 1997) |
| "Atracurium was again given by infusion to maintain 40% twitch for a second hour, then 2 mg gentamycin/kg bwt were given i." | 1.29 | Interaction of gentamycin and atracurium in anaesthetised horses. ( Hildebrand, SV; Hill, T, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (60.00) | 18.7374 |
| 1990's | 10 (25.00) | 18.2507 |
| 2000's | 4 (10.00) | 29.6817 |
| 2010's | 2 (5.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zagorchev, P | 1 |
| Petkov, GV | 1 |
| Gagov, HS | 1 |
| Lee, SI | 1 |
| Lee, JH | 2 |
| Lee, SC | 1 |
| Lee, JM | 1 |
| Singh, D | 1 |
| Singh, MR | 1 |
| Stoleru, S | 1 |
| Fulga, C | 1 |
| Zugravu, A | 1 |
| Taranu, B | 1 |
| Fulga, I | 1 |
| Morales, AI | 1 |
| Rodríguez-Barbero, A | 1 |
| Vicente-Sánchez, C | 1 |
| Mayoral, P | 1 |
| López-Novoa, JM | 1 |
| Pérez-Barriocanal, F | 1 |
| Papaioannidou, PG | 2 |
| Karakiulakis, G | 2 |
| Salpigides, G | 1 |
| Triantaphyllidis, C | 3 |
| Zachariades, B | 1 |
| Paradelis, AG | 3 |
| Scriabine, A | 1 |
| Anderson, CL | 1 |
| Janis, RA | 1 |
| Kojima, K | 1 |
| Rasmussen, H | 1 |
| Lee, S | 1 |
| Michal, U | 1 |
| Dolgova, GV | 4 |
| Berezhinskaia, VV | 2 |
| Lippmann, M | 1 |
| Yang, E | 1 |
| Au, E | 1 |
| Lee, C | 1 |
| Giardina, WJ | 1 |
| Wismer, CT | 1 |
| Dehpour, AR | 1 |
| Samadian, T | 1 |
| Rassaee, N | 1 |
| Lennon, GM | 1 |
| Ryan, PC | 1 |
| Fitzpatrick, JM | 1 |
| Hildebrand, SV | 1 |
| Hill, T | 1 |
| Henson, OW | 1 |
| Xie, DH | 1 |
| Keating, AW | 1 |
| Henson, MM | 1 |
| Singh, YN | 1 |
| Johnson, A | 1 |
| Lulf, LA | 1 |
| Singh, BN | 1 |
| Matsukawa, S | 1 |
| Suh, JH | 1 |
| Hashimoto, Y | 2 |
| Kato, M | 2 |
| Satoh, D | 1 |
| Saito, S | 1 |
| Endo, K | 1 |
| Saishu, T | 1 |
| Hague, BA | 1 |
| Martinez, EA | 1 |
| Hartsfield, SM | 1 |
| Barton-Davis, ER | 1 |
| Cordier, L | 1 |
| Shoturma, DI | 1 |
| Leland, SE | 1 |
| Sweeney, HL | 1 |
| Liu, M | 1 |
| Bykova, MA | 1 |
| Solv'ev, VN | 1 |
| Egorenko, GG | 1 |
| Solov'ev, VN | 2 |
| de Rosayro, M | 1 |
| Healy, TE | 1 |
| Brunder, DG | 1 |
| Györke, S | 1 |
| Dettbarn, C | 1 |
| Palade, P | 1 |
| Lüllmann, H | 1 |
| Ziegler, A | 1 |
| Hashimoto, H | 1 |
| Yanagisawa, T | 2 |
| Taira, N | 2 |
| Foldes, FF | 1 |
| Bikhazi, GB | 1 |
| Jedeikin, R | 1 |
| Dolgunski, E | 1 |
| Kaplan, R | 1 |
| Hoffman, S | 1 |
| Gotanda, K | 1 |
| Satoh, K | 1 |
| Parker, JL | 1 |
| Adams, HR | 2 |
| Tolliver, JM | 1 |
| Warnick, JE | 1 |
| Barnett, A | 1 |
| Ackermann, E | 1 |
| Dretchen, KL | 1 |
| Gergis, SD | 1 |
| Sokoll, MD | 1 |
| Long, JP | 1 |
| Fidani, V | 1 |
| Logaras, G | 1 |
| Nielsen, AB | 1 |
| Elb, S | 1 |
| Benzi, G | 2 |
| Arrigoni, E | 2 |
| Panceri, P | 2 |
| Bertè, F | 1 |
| Panzarasa, R | 1 |
| Berte', F | 1 |
| Crema, A | 1 |
| Murav'eva, SA | 1 |
| Vital Brazil, O | 1 |
| Prado-Franceschi, J | 1 |
1 trial available for gentamicin and Muscle Contraction
| Article | Year |
|---|---|
Neuromuscular blocking effects of tobramycin, gentamicin, and cefazolin.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cefazolin; Drug Interactions; Electric Stimulation; | 1982 |
39 other studies available for gentamicin and Muscle Contraction
| Article | Year |
|---|---|
Bitter Taste Receptors as Regulators of Abdominal Muscles Contraction.
Topics: Abdominal Muscles; Animals; Gentamicins; Male; Muscle Contraction; Organ Culture Techniques; Rats; R | 2019 |
Calcium and neostigmine antagonize gentamicin, but augment clindamycin-induced tetanic fade in rat phrenic nerve-hemidiaphragm preparations.
Topics: Animals; Anti-Bacterial Agents; Calcium; Clindamycin; Diaphragm; Electric Stimulation; Gentamicins; | 2008 |
Development of antibiotic and debriding enzyme-loaded PLGA microspheres entrapped in PVA-gelatin hydrogel for complete wound management.
Topics: Animals; Biocompatible Materials; Debridement; Drug Combinations; Gelatin; Gentamicins; Guided Tissu | 2012 |
Effect of kanamycin and gentamicin on frog n. sciatic--m. gastrocnemian preparation.
Topics: Animals; Anti-Bacterial Agents; Anura; Dose-Response Relationship, Drug; Electric Stimulation; Genta | 2003 |
Resveratrol inhibits gentamicin-induced mesangial cell contraction.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Cell Size; Cells, Cultured; Enzyme Inhibitors; Gentami | 2006 |
Inhibition of vas deferens contractility caused by aminoglycoside antibiotics.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Gentamicins; Guinea Pigs; Male; Models, Animal; Mus | 1989 |
Some recent pharmacological findings with nitrendipine.
Topics: Acute Kidney Injury; Adrenal Glands; Aldosterone; Angiotensin II; Animals; Calcium; Calcium Channel | 1984 |
[Effect of sisomicin i on elements of the peripheral nervous system].
Topics: Animals; Cats; Dose-Response Relationship, Drug; Gentamicins; Hemodynamics; In Vitro Techniques; Iso | 1983 |
The rat-pull test procedure: a method for assessing the strength of rats.
Topics: Acrylamide; Acrylamides; Animals; Diazepam; Ergometry; Evaluation Studies as Topic; Gentamicins; Mal | 1995 |
Diabetic rats show more resistance to neuromuscular blockade induced by aminoglycoside antibiotics.
Topics: Animals; Anti-Bacterial Agents; Diabetes Mellitus, Experimental; Drug Resistance; Female; Gentamicin | 1993 |
The ureter in vitro: normal motility and response to urinary pathogens.
Topics: Animals; Bacterial Infections; Dinoprost; Dogs; Endotoxins; Escherichia coli Infections; Gentamicins | 1993 |
Interaction of gentamycin and atracurium in anaesthetised horses.
Topics: Anesthetics, Inhalation; Animals; Anti-Bacterial Agents; Atracurium; Drug Interactions; Drug Synergi | 1994 |
The effect of contralateral stimulation on cochlear resonance and damping in the mustached bat: the role of the medial efferent system.
Topics: Acoustic Stimulation; Animals; Anti-Bacterial Agents; Chiroptera; Cochlea; Cochlear Microphonic Pote | 1995 |
Study of in vitro and in vitro effects of isradipine in skeletal muscles and interaction with some drugs.
Topics: Animals; Anti-Bacterial Agents; Calcium Channel Blockers; Clindamycin; Diaphragm; Dose-Response Rela | 1996 |
Neuromuscular blocking actions of the aminoglycoside antibiotics sisomicin and micronomicin in the rabbit.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Calcium; Dose-Response Relationship, Drug; Gentamic | 1997 |
Effects of high-dose gentamicin sulfate on neuromuscular blockade in halothane-anesthetized horses.
Topics: Analysis of Variance; Anesthesia, Inhalation; Anesthetics, Inhalation; Animals; Anti-Bacterial Agent | 1997 |
Aminoglycoside antibiotics restore dystrophin function to skeletal muscles of mdx mice.
Topics: Animals; Anti-Bacterial Agents; Cell Membrane; Cells, Cultured; Codon, Terminator; Dose-Response Rel | 1999 |
Neuromuscular blocking effects of the aminoglycoside antibiotics arbekacin, astromicin, isepamicin and netilmicin on the diaphragm and limb muscles in the rabbit.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Diaphragm; Dibekacin; Dose-Response Relationship, D | 2001 |
[Pharmacology of gentamicin sulfate].
Topics: Animals; Bile; Blood; Blood Cells; Cats; Gentamicins; Growth; Guinea Pigs; Hearing; Kidney; Lethal D | 1976 |
[Mechanism of the peripheral myorelatant action of aminocyclitol antibiotics].
Topics: Acetylcholine; Aminoglycosides; Animals; Anti-Bacterial Agents; Axons; Calcium; Dose-Response Relati | 1976 |
Tobramycin and neuromuscular transmission in the rat isolated phrenic nerve-diaphragm preparation.
Topics: Animals; Anti-Bacterial Agents; Gentamicins; In Vitro Techniques; Male; Muscle Contraction; Neomycin | 1978 |
Involvement of sarcoplasmic reticulum 'Ca2+ release channels' in excitation-contraction coupling in vertebrate skeletal muscle.
Topics: Animals; Caffeine; Calcium; Calcium Channels; Computer Simulation; Electric Stimulation; Electrophys | 1992 |
Critical remarks on the Ca-flux determinations in smooth and cardiac muscle.
Topics: Animals; Biological Transport, Active; Calcium; Cell Membrane; Gentamicins; Guinea Pigs; In Vitro Te | 1987 |
Differential antagonism of the negative inotropic effect of gentamicin by calcium ions, Bay K 8644 and isoprenaline in canine ventricular muscle: comparison with cobalt ions.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1989 |
The influence of temperature and calcium concentration on the myoneural effect of antibiotics.
Topics: Acetylcholinesterase; Animals; Anti-Bacterial Agents; Body Temperature; Calcium; Gentamicins; Male; | 1989 |
Prolongation of neuromuscular blocking effect of vecuronium by antibiotics.
Topics: Clindamycin; Drug Synergism; Female; Gentamicins; Humans; Middle Aged; Muscle Contraction; Neuromusc | 1987 |
Are the cardiovascular effects of gentamicin similar to those of calcium antagonists?
Topics: Animals; Atrioventricular Node; Calcium Channel Blockers; Coronary Circulation; Dogs; Electric Stimu | 1988 |
A study of the mechanism of action of aminoglycoside antibiotics on the guinea pig vas deferens.
Topics: Animals; Anti-Bacterial Agents; Calcium; Gentamicins; Guinea Pigs; In Vitro Techniques; Male; Muscle | 1988 |
Development of myocardial dysfunction in endotoxin shock.
Topics: Animals; Calcium; Gentamicins; Guinea Pigs; Heart; Hypoxia; Male; Muscle Contraction; Myocardial Con | 1985 |
Aminoglycoside-induced biphasic hindlimb paralysis in the rat: a histological and electrophysiological assessment.
Topics: Action Potentials; Aminoglycosides; Animals; Anti-Bacterial Agents; Female; Gentamicins; Hindlimb; M | 1985 |
Neuromuscular blocking effect of aminoglycoside antibiotics in nonhuman primates.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Calcium Chloride; Dihydrostreptomycin Sulfate; Gent | 1973 |
Neuromuscular blocking activity of gentamicin in cats and mice.
Topics: Animals; Blood Pressure; Cats; Curare; Drug Antagonism; Drug Synergism; Female; Gentamicins; Kanamyc | 1969 |
Effect of various antibiotics on neuromuscular transmission.
Topics: Acetylcholine; Animals; Anti-Bacterial Agents; Anura; Depression, Chemical; Electric Stimulation; Ge | 1972 |
The action of the aminoglycosidic antibiotic gentamicin of the isolated rat diaphragm. Potentiation of the neuromuscular blocking activity of gentamicin during combined application with muscle relaxant agents and magnesium.
Topics: Animals; Calcium; Diaphragm; Drug Synergism; Electric Stimulation; Gentamicins; In Vitro Techniques; | 1974 |
The use of gentamicin intravenously.
Topics: Adolescent; Adult; Aged; Child; Creatinine; Depression, Chemical; Female; Gentamicins; Hearing Disor | 1973 |
Action of gentamicin, aminosidin, and ampicillin on uterine tone and motility.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Depression, Chemical; Dogs; Female; Gentamicins; Guinea | 1972 |
Effect of antibiotics on the ureter motor activity.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Chloramphenicol; Cloxacillin; Dicloxacillin; Dogs; Femal | 1973 |
[The nature of the antagonism between aminocycletol antibiotics and acetylcholine].
Topics: Acetylcholine; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Gentamicins; Mathem | 1974 |
The nature of neuromuscular block produced by neomycin and gentamicin.
Topics: Acetylcholine; Animals; Atropine; Blood Pressure; Calcium; Depression, Chemical; Diaphragm; Gentamic | 1969 |