Page last updated: 2024-10-27

gentamicin and Middle Ear Inflammation

gentamicin has been researched along with Middle Ear Inflammation in 39 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Research Excerpts

ExcerptRelevanceReference
"A multicentre double-blind randomized study was carried out to compare topical ciprofloxacin and topical gentamicin in the treatment of simple non-cholesteatomatous purulent chronic otitis media."9.08[Multicenter study comparing the efficacy and tolerance of topical ciprofloxacin (0.3%) versus topical gentamicin (0.3%) in the treatment of simple, non-cholesteatomaous chronic otitis media in the suppurative phase]. ( Abelló, P; Dicenta, M; Jiménez, R; Lorente, J; Maristany, M; Menem, J; Quesada, P; Sabater, F; Traserra, J; Viñas, J, 1995)
"Clinical and bacteriological efficacy of topical ciprofloxacin hydrochloride was compared with that of intramuscular gentamicin sulfate in two groups composed of 30 patients each, all of whom were affected by chronic otitis media in the acute stage."9.07Topical ciprofloxacin vs intramuscular gentamicin for chronic otitis media. ( D'Errico, G; Esposito, S; Montanaro, C; Noviello, S, 1992)
"A prospective study was performed on patients with active mucosal chronic otitis media who were being treated with the gentamicin-containing preparation Gentisone HC."7.70Systemic absorption of gentamicin in the management of active mucosal chronic otitis media. ( Hart, CA; Lancaster, JL; McCormick, M; Mortimore, S, 1999)
"Primary: to compare one-off administration of boric acid powder with courses of 1% acetic acid and ciprofloxacin eardrops in treating active chronic otitis media."5.16A randomised controlled trial of active chronic otitis media comparing courses of eardrops versus one-off topical treatments suitable for primary, secondary and tertiary healthcare settings. ( Loock, JW, 2012)
"A multicentre double-blind randomized study was carried out to compare topical ciprofloxacin and topical gentamicin in the treatment of simple non-cholesteatomatous purulent chronic otitis media."5.08[Multicenter study comparing the efficacy and tolerance of topical ciprofloxacin (0.3%) versus topical gentamicin (0.3%) in the treatment of simple, non-cholesteatomaous chronic otitis media in the suppurative phase]. ( Abelló, P; Dicenta, M; Jiménez, R; Lorente, J; Maristany, M; Menem, J; Quesada, P; Sabater, F; Traserra, J; Viñas, J, 1995)
"Clinical and bacteriological efficacy of topical ciprofloxacin hydrochloride was compared with that of intramuscular gentamicin sulfate in two groups composed of 30 patients each, all of whom were affected by chronic otitis media in the acute stage."5.07Topical ciprofloxacin vs intramuscular gentamicin for chronic otitis media. ( D'Errico, G; Esposito, S; Montanaro, C; Noviello, S, 1992)
"The aim of this study was to evaluate whether, in the treatment of active non-cholesteatomatous chronic otitis media, the effectiveness of gentamicin with hydrocortisone ear-drops is due solely to the contained steroid or to the combination of antibiotic and steroid."5.07Medical treatment of chronic otitis media: steroid or antibiotic with steroid ear-drops? ( Crowther, JA; Simpson, D, 1991)
"Brainstem auditory evoked responses in dogs treated with aqueous solutions of marbofloxacin or gentamicin remained unchanged or improved after therapy of otitis media but were impaired in dogs treated with ticarcillin or tobramycin."3.88Brainstem auditory evoked responses in 37 dogs with otitis media before and after topical therapy. ( Paterson, S, 2018)
"Gentamicin solution at concentrations of either 30 or 3 mg/mL was infused daily into the left middle ear of adult cats until overt ataxia occurred."3.72Gentamicin tympanoclysis: effects on the labyrinthine sensory cells. ( Pender, DJ, 2003)
"A prospective study was performed on patients with active mucosal chronic otitis media who were being treated with the gentamicin-containing preparation Gentisone HC."3.70Systemic absorption of gentamicin in the management of active mucosal chronic otitis media. ( Hart, CA; Lancaster, JL; McCormick, M; Mortimore, S, 1999)
"Lemierre syndrome is a disease that every pediatrician must know."1.35[Lemierre syndrome: a complication of an oropharyngeal infection]. ( Bailly, C; Berlioz, M; Boutté, P; Passalidou, P, 2008)
"Gentamicin was found to be released more slowly from the fibrin-gelatin mixture than from the fibrin mixture in this experiment."1.30Sustained release of antibiotic from a fibrin-gelatin-antibiotic mixture. ( Kim, YB; Park, MS, 1997)
"Insertion of tympanostomy tubes for the treatment of otitis media is the most frequently performed otologic operation, and postoperative otorrhea is its most common complication."1.30Prophylactic treatment after ventilation tube insertion: comparison of various methods. ( Ghersin, T; Gilbert, LM; Golz, A; Joachims, HZ; Netzer, A; Westerman, ST, 1998)
" The prophylactic effect upon ototoxicity of the administration of dimercaptopropanol or of dividing up the daily dosage was examined."1.26[Ototoxicity of the aminoglycoside antibiotics (author's transl)]. ( Federspil, P, 1976)

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-199021 (53.85)18.7374
1990's9 (23.08)18.2507
2000's4 (10.26)29.6817
2010's4 (10.26)24.3611
2020's1 (2.56)2.80

Authors

AuthorsStudies
Chai, Y1
He, W1
Yang, W1
Hetrick, AP1
Gonzalez, JG1
Sargsyan, L1
Wu, H1
Jung, TTK1
Li, H1
Paterson, S1
Korkmaz, S1
Ceylan, ME1
Ceylan, G1
Dalgıç, A1
İnan, S1
Olgun, L1
Özüer, MZ1
Woo, JI1
Oh, S1
Webster, P1
Lee, YJ1
Lim, DJ1
Moon, SK1
Hernandez, M1
Leichtle, A1
Pak, K1
Ebmeyer, J1
Euteneuer, S1
Obonyo, M1
Guiney, DG1
Webster, NJ1
Broide, DH1
Ryan, AF1
Wasserman, SI1
Passalidou, P1
Berlioz, M1
Bailly, C1
Boutté, P1
Loock, JW1
Pender, DJ1
Drobbin, MT1
Phelan, ST1
Antonelli, PJ1
Coker, AO1
Ijaduola, GT1
Odugbemi, TO1
Gydé, MC2
Norris, D1
Kavalec, EC1
Brook, I2
Lorente, J1
Sabater, F1
Maristany, M1
Jiménez, R1
Menem, J1
Viñas, J1
Quesada, P1
Traserra, J1
Dicenta, M1
Abelló, P1
Cotter, CS1
Avidano, MA1
Stringer, SP1
Schultz, GS1
Wong, DL1
Rutka, JA1
Park, MS1
Kim, YB1
Golz, A1
Ghersin, T1
Joachims, HZ1
Westerman, ST1
Gilbert, LM1
Netzer, A1
Reiss, M1
Lancaster, JL1
Mortimore, S1
McCormick, M1
Hart, CA1
Meyerhoff, WL1
Gates, GA1
Montalbo, PJ1
Badré, R1
Guillerm, R1
Mouel, C1
Poiret, F1
Wagner, WH1
Federspil, P1
Lin, RG1
Arcala, AE1
Esposito, S1
Noviello, S1
D'Errico, G1
Montanaro, C1
Crowther, JA1
Simpson, D1
Baker, RS1
Chole, RA1
Browning, GG1
Gatehouse, S1
Calder, IT1
Sambe, B1
Murakami, H1
Kobayasi, K1
Jo, K1
Inafuku, S1
von Graevenitz, A1
Carrington, GO1
Riff, LJ1
McCracken, GH1
Eichenwald, HF1
Washington, JA1
Weichselbaumer, W1
Majkus, V2
Horáková, Z1
Výmola, F1
Stol, M1
Vacek, V1
Stafová, J1
Sýkorová, L1

Reviews

2 reviews available for gentamicin and Middle Ear Inflammation

ArticleYear
Chemotherapy in ear disease.
    Otolaryngologic clinics of North America, 1972, Volume: 5, Issue:1

    Topics: Acute Disease; Child; Child, Preschool; Chlorpheniramine; Chronic Disease; Ear, Middle; Enterobacter

1972
Antimicrobiol therapy: therapeutic recommendations and a review of newer drugs. Part I. Therapy of infectious conditions.
    The Journal of pediatrics, 1974, Volume: 85, Issue:3

    Topics: Adolescent; Ampicillin; Anti-Bacterial Agents; Arthritis, Infectious; Bacteroides Infections; Brain

1974

Trials

7 trials available for gentamicin and Middle Ear Inflammation

ArticleYear
A randomised controlled trial of active chronic otitis media comparing courses of eardrops versus one-off topical treatments suitable for primary, secondary and tertiary healthcare settings.
    Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery, 2012, Volume: 37, Issue:4

    Topics: Acetic Acid; Administration, Topical; Adult; Analysis of Variance; Anti-Infective Agents; Audiometry

2012
The weeping ear: clinical re-evaluation of treatment.
    The Journal of international medical research, 1982, Volume: 10, Issue:5

    Topics: Adult; Bacterial Infections; Chronic Disease; Clinical Trials as Topic; Colistin; Double-Blind Metho

1982
[Multicenter study comparing the efficacy and tolerance of topical ciprofloxacin (0.3%) versus topical gentamicin (0.3%) in the treatment of simple, non-cholesteatomaous chronic otitis media in the suppurative phase].
    Anales otorrinolaringologicos ibero-americanos, 1995, Volume: 22, Issue:5

    Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Bacterial Agents; Aspergillus; Candida albica

1995
Topical ciprofloxacin vs intramuscular gentamicin for chronic otitis media.
    Archives of otolaryngology--head & neck surgery, 1992, Volume: 118, Issue:8

    Topics: Administration, Topical; Adult; Chronic Disease; Ciprofloxacin; Female; Gentamicins; Humans; Injecti

1992
Medical treatment of chronic otitis media: steroid or antibiotic with steroid ear-drops?
    Clinical otolaryngology and allied sciences, 1991, Volume: 16, Issue:2

    Topics: Betamethasone; Chronic Disease; Drug Combinations; Evaluation Studies as Topic; Female; Gentamicins;

1991
A randomized clinical trial of topical gentamicin after tympanostomy tube placement.
    Archives of otolaryngology--head & neck surgery, 1988, Volume: 114, Issue:7

    Topics: Administration, Topical; Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Clinical Tri

1988
Medical management of active chronic otitis media: a controlled study.
    The Journal of laryngology and otology, 1988, Volume: 102, Issue:6

    Topics: Administration, Oral; Administration, Topical; Adult; Aged; Chronic Disease; Clinical Trials as Topi

1988

Other Studies

30 other studies available for gentamicin and Middle Ear Inflammation

ArticleYear
Intratympanic Lipopolysaccharide Elevates Systemic Fluorescent Gentamicin Uptake in the Cochlea.
    The Laryngoscope, 2021, Volume: 131, Issue:9

    Topics: Animals; Cochlea; Cytokines; Disease Models, Animal; Gentamicins; Injection, Intratympanic; Lipopoly

2021
Brainstem auditory evoked responses in 37 dogs with otitis media before and after topical therapy.
    The Journal of small animal practice, 2018, Volume: 59, Issue:1

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Dogs; Ear, Middle; Evoked Potentials, Audit

2018
Auditory and Histopathological Effects of Topical Mercurochrome Treatment in Rats with Tympanic Membrane Perforation.
    The journal of international advanced otology, 2019, Volume: 15, Issue:1

    Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Cochlea; Female; Gentamicins; Hearing; Merb

2019
NOD2/RICK-dependent β-defensin 2 regulation is protective for nontypeable Haemophilus influenzae-induced middle ear infection.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; beta-Defensins; Cell Line; Cytoplasm; Ear, Middle; Endocytosis; Gene Expression Regulation;

2014
Myeloid differentiation primary response gene 88 is required for the resolution of otitis media.
    The Journal of infectious diseases, 2008, Dec-15, Volume: 198, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Ear, Middle; Gene Expression Regulation; Gentamicins; Haemophilus In

2008
[Lemierre syndrome: a complication of an oropharyngeal infection].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2008, Volume: 15, Issue:12

    Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; Cefotax

2008
Gentamicin tympanoclysis: effects on the labyrinthine sensory cells.
    The Laryngoscope, 2003, Volume: 113, Issue:2

    Topics: Acoustic Maculae; Animals; Anti-Bacterial Agents; Ataxia; Cats; Ear, Middle; Gentamicins; Hair Cells

2003
Dexamethasone does not alter in vitro antibacterial efficacy of gentamicin.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 2007, Volume: 136, Issue:5

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Dexamethasone; Drug Administration Schedule; Gentam

2007
Bacterial isolates from chronic discharging ears in Nigerian children.
    East African medical journal, 1983, Volume: 60, Issue:7

    Topics: Adolescent; Child; Child, Preschool; Chronic Disease; Drug Resistance, Microbial; Female; Gentamicin

1983
Clindamycin in treatment of chronic recurrent suppurative otitis media in children.
    The Journal of laryngology and otology, 1980, Volume: 94, Issue:6

    Topics: Bacteria; Child; Child, Preschool; Chronic Disease; Clindamycin; Drug Administration Schedule; Femal

1980
Inhibition of proteases in Pseudomonas otitis media in chinchillas.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1996, Volume: 115, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Chinchilla; Dipeptides; Disease Models, Animal; Gentamicins; Otitis

1996
Do aminoglycoside otic preparations cause ototoxicity in the presence of tympanic membrane perforations?
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1997, Volume: 116, Issue:3

    Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Ear, Inner; Female; Gentamicins; Hearin

1997
Sustained release of antibiotic from a fibrin-gelatin-antibiotic mixture.
    The Laryngoscope, 1997, Volume: 107, Issue:10

    Topics: Administration, Topical; Ampicillin; Anti-Bacterial Agents; Bacillus subtilis; Delayed-Action Prepar

1997
Prophylactic treatment after ventilation tube insertion: comparison of various methods.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1998, Volume: 119, Issue:1

    Topics: Administration, Oral; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Age

1998
[When do ear drops help, when are they harmful?].
    Fortschritte der Medizin, 1999, Apr-30, Volume: 117, Issue:12

    Topics: Administration, Topical; Chloramphenicol; Contraindications; Drug-Related Side Effects and Adverse R

1999
Systemic absorption of gentamicin in the management of active mucosal chronic otitis media.
    Clinical otolaryngology and allied sciences, 1999, Volume: 24, Issue:5

    Topics: Absorption; Adult; Anti-Bacterial Agents; Chronic Disease; Female; Gentamicins; Humans; Male; Otitis

1999
Anaerobic isolates in chronic recurrent suppurative otitis media. Treatment with carbenicillin alone and in combination with gentamicin.
    Infection, 1979, Volume: 7, Issue:5

    Topics: Adolescent; Anaerobiosis; Bacteria; Bacteroides fragilis; Carbenicillin; Child; Child, Preschool; Dr

1979
Pseudomonas mastoiditis.
    The Laryngoscope, 1977, Volume: 87, Issue:4 Pt 1

    Topics: Adult; Aged; Carbenicillin; Colistin; Diabetes Mellitus; Female; Gentamicins; Humans; Infant; Male;

1977
[Experimental results and use of the manosonic aerosoliser (U.D.V.) for the treatment of middle-ear and affections (author's transl)].
    Laryngologie, Rhinologie, Otologie, 1978, Volume: 57, Issue:7

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Evaluation Studies as Topic; Female; Gentamicins;

1978
[Special problems in the chemotherapy of bacterial infections in otolaryngology (author's transl)].
    HNO, 1977, Volume: 25, Issue:11

    Topics: Aminoglycosides; Bacterial Infections; Ear; Gentamicins; Humans; Kanamycin; Neomycin; Otitis Media;

1977
When the weeping stopped: an otologist views otorrhea and gentamicin.
    Archives of otolaryngology (Chicago, Ill. : 1960), 1976, Volume: 102, Issue:9

    Topics: Administration, Topical; Chronic Disease; Gentamicins; Hearing; Myringoplasty; Otitis Externa; Otiti

1976
[Ototoxicity of the aminoglycoside antibiotics (author's transl)].
    Infection, 1976, Volume: 4, Issue:4

    Topics: Acid Phosphatase; Alkaline Phosphatase; Amikacin; Animals; Anti-Bacterial Agents; Child; Ear, Inner;

1976
Fusobacterium septicemia with otitis media and mastoiditis.
    Postgraduate medicine, 1975, Volume: 57, Issue:4

    Topics: Bacterial Infections; Drainage; Female; Fusobacterium; Gentamicins; Humans; Infant; Mastoid; Mastoid

1975
[Treatment of otorhinolaryngological infections with BB-K8 (author's transl)].
    The Japanese journal of antibiotics, 1974, Volume: 27, Issue:3

    Topics: Acute Disease; Adult; Child; Child, Preschool; Female; Gentamicins; Humans; Infant; Kanamycin; Male;

1974
Halophilic vibrios from extraintestinal lesions in man.
    Infection, 1973, Volume: 1, Issue:1

    Topics: Accidents, Aviation; Adult; Aged; Cephalothin; Erythromycin; Female; Gallbladder Diseases; Gangrene;

1973
Aeromonas hydrophila in clinical bacteriologic specimens.
    Annals of internal medicine, 1972, Volume: 76, Issue:4

    Topics: Aeromonas; Bacterial Infections; Blood; Gentamicins; Humans; Otitis Media; Postoperative Complicatio

1972
[Surgical therapy of Pseudomonas aeruginosa infections in chronic otitis media].
    Monatsschrift fur Ohrenheilkunde und Laryngo-Rhinologie, 1971, Volume: 105, Issue:3

    Topics: Adult; Female; Gentamicins; Humans; Male; Middle Aged; Otitis Media; Preoperative Care; Pseudomonas

1971
Employment of hydron polymer antibiotic vehicle in otolaryngology.
    Journal of biomedical materials research, 1969, Volume: 3, Issue:3

    Topics: Acrylates; Animals; Anti-Bacterial Agents; Bacitracin; Biological Assay; Chloramphenicol; Colistin;

1969
[Clinical experience with gentamicin in resistant gramnegative infections].
    Casopis lekaru ceskych, 1970, Apr-17, Volume: 109, Issue:17

    Topics: Adolescent; Adult; Female; Gentamicins; Humans; Infant; Infections; Male; Middle Aged; Otitis Media;

1970
[The use of glycolmetacrylate-gel saturated with antibiotics in tympanoplasty].
    HNO, 1970, Volume: 18, Issue:2

    Topics: Acrylates; Anti-Bacterial Agents; Bacitracin; Chloramphenicol; Chronic Disease; Colistin; Gels; Gent

1970