gentamicin has been researched along with Middle Ear Inflammation in 39 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A multicentre double-blind randomized study was carried out to compare topical ciprofloxacin and topical gentamicin in the treatment of simple non-cholesteatomatous purulent chronic otitis media." | 9.08 | [Multicenter study comparing the efficacy and tolerance of topical ciprofloxacin (0.3%) versus topical gentamicin (0.3%) in the treatment of simple, non-cholesteatomaous chronic otitis media in the suppurative phase]. ( Abelló, P; Dicenta, M; Jiménez, R; Lorente, J; Maristany, M; Menem, J; Quesada, P; Sabater, F; Traserra, J; Viñas, J, 1995) |
| "Clinical and bacteriological efficacy of topical ciprofloxacin hydrochloride was compared with that of intramuscular gentamicin sulfate in two groups composed of 30 patients each, all of whom were affected by chronic otitis media in the acute stage." | 9.07 | Topical ciprofloxacin vs intramuscular gentamicin for chronic otitis media. ( D'Errico, G; Esposito, S; Montanaro, C; Noviello, S, 1992) |
| "A prospective study was performed on patients with active mucosal chronic otitis media who were being treated with the gentamicin-containing preparation Gentisone HC." | 7.70 | Systemic absorption of gentamicin in the management of active mucosal chronic otitis media. ( Hart, CA; Lancaster, JL; McCormick, M; Mortimore, S, 1999) |
| "Primary: to compare one-off administration of boric acid powder with courses of 1% acetic acid and ciprofloxacin eardrops in treating active chronic otitis media." | 5.16 | A randomised controlled trial of active chronic otitis media comparing courses of eardrops versus one-off topical treatments suitable for primary, secondary and tertiary healthcare settings. ( Loock, JW, 2012) |
| "A multicentre double-blind randomized study was carried out to compare topical ciprofloxacin and topical gentamicin in the treatment of simple non-cholesteatomatous purulent chronic otitis media." | 5.08 | [Multicenter study comparing the efficacy and tolerance of topical ciprofloxacin (0.3%) versus topical gentamicin (0.3%) in the treatment of simple, non-cholesteatomaous chronic otitis media in the suppurative phase]. ( Abelló, P; Dicenta, M; Jiménez, R; Lorente, J; Maristany, M; Menem, J; Quesada, P; Sabater, F; Traserra, J; Viñas, J, 1995) |
| "Clinical and bacteriological efficacy of topical ciprofloxacin hydrochloride was compared with that of intramuscular gentamicin sulfate in two groups composed of 30 patients each, all of whom were affected by chronic otitis media in the acute stage." | 5.07 | Topical ciprofloxacin vs intramuscular gentamicin for chronic otitis media. ( D'Errico, G; Esposito, S; Montanaro, C; Noviello, S, 1992) |
| "The aim of this study was to evaluate whether, in the treatment of active non-cholesteatomatous chronic otitis media, the effectiveness of gentamicin with hydrocortisone ear-drops is due solely to the contained steroid or to the combination of antibiotic and steroid." | 5.07 | Medical treatment of chronic otitis media: steroid or antibiotic with steroid ear-drops? ( Crowther, JA; Simpson, D, 1991) |
| "Brainstem auditory evoked responses in dogs treated with aqueous solutions of marbofloxacin or gentamicin remained unchanged or improved after therapy of otitis media but were impaired in dogs treated with ticarcillin or tobramycin." | 3.88 | Brainstem auditory evoked responses in 37 dogs with otitis media before and after topical therapy. ( Paterson, S, 2018) |
| "Gentamicin solution at concentrations of either 30 or 3 mg/mL was infused daily into the left middle ear of adult cats until overt ataxia occurred." | 3.72 | Gentamicin tympanoclysis: effects on the labyrinthine sensory cells. ( Pender, DJ, 2003) |
| "A prospective study was performed on patients with active mucosal chronic otitis media who were being treated with the gentamicin-containing preparation Gentisone HC." | 3.70 | Systemic absorption of gentamicin in the management of active mucosal chronic otitis media. ( Hart, CA; Lancaster, JL; McCormick, M; Mortimore, S, 1999) |
| "Lemierre syndrome is a disease that every pediatrician must know." | 1.35 | [Lemierre syndrome: a complication of an oropharyngeal infection]. ( Bailly, C; Berlioz, M; Boutté, P; Passalidou, P, 2008) |
| "Gentamicin was found to be released more slowly from the fibrin-gelatin mixture than from the fibrin mixture in this experiment." | 1.30 | Sustained release of antibiotic from a fibrin-gelatin-antibiotic mixture. ( Kim, YB; Park, MS, 1997) |
| "Insertion of tympanostomy tubes for the treatment of otitis media is the most frequently performed otologic operation, and postoperative otorrhea is its most common complication." | 1.30 | Prophylactic treatment after ventilation tube insertion: comparison of various methods. ( Ghersin, T; Gilbert, LM; Golz, A; Joachims, HZ; Netzer, A; Westerman, ST, 1998) |
| " The prophylactic effect upon ototoxicity of the administration of dimercaptopropanol or of dividing up the daily dosage was examined." | 1.26 | [Ototoxicity of the aminoglycoside antibiotics (author's transl)]. ( Federspil, P, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (53.85) | 18.7374 |
| 1990's | 9 (23.08) | 18.2507 |
| 2000's | 4 (10.26) | 29.6817 |
| 2010's | 4 (10.26) | 24.3611 |
| 2020's | 1 (2.56) | 2.80 |
| Authors | Studies |
|---|---|
| Chai, Y | 1 |
| He, W | 1 |
| Yang, W | 1 |
| Hetrick, AP | 1 |
| Gonzalez, JG | 1 |
| Sargsyan, L | 1 |
| Wu, H | 1 |
| Jung, TTK | 1 |
| Li, H | 1 |
| Paterson, S | 1 |
| Korkmaz, S | 1 |
| Ceylan, ME | 1 |
| Ceylan, G | 1 |
| Dalgıç, A | 1 |
| İnan, S | 1 |
| Olgun, L | 1 |
| Özüer, MZ | 1 |
| Woo, JI | 1 |
| Oh, S | 1 |
| Webster, P | 1 |
| Lee, YJ | 1 |
| Lim, DJ | 1 |
| Moon, SK | 1 |
| Hernandez, M | 1 |
| Leichtle, A | 1 |
| Pak, K | 1 |
| Ebmeyer, J | 1 |
| Euteneuer, S | 1 |
| Obonyo, M | 1 |
| Guiney, DG | 1 |
| Webster, NJ | 1 |
| Broide, DH | 1 |
| Ryan, AF | 1 |
| Wasserman, SI | 1 |
| Passalidou, P | 1 |
| Berlioz, M | 1 |
| Bailly, C | 1 |
| Boutté, P | 1 |
| Loock, JW | 1 |
| Pender, DJ | 1 |
| Drobbin, MT | 1 |
| Phelan, ST | 1 |
| Antonelli, PJ | 1 |
| Coker, AO | 1 |
| Ijaduola, GT | 1 |
| Odugbemi, TO | 1 |
| Gydé, MC | 2 |
| Norris, D | 1 |
| Kavalec, EC | 1 |
| Brook, I | 2 |
| Lorente, J | 1 |
| Sabater, F | 1 |
| Maristany, M | 1 |
| Jiménez, R | 1 |
| Menem, J | 1 |
| Viñas, J | 1 |
| Quesada, P | 1 |
| Traserra, J | 1 |
| Dicenta, M | 1 |
| Abelló, P | 1 |
| Cotter, CS | 1 |
| Avidano, MA | 1 |
| Stringer, SP | 1 |
| Schultz, GS | 1 |
| Wong, DL | 1 |
| Rutka, JA | 1 |
| Park, MS | 1 |
| Kim, YB | 1 |
| Golz, A | 1 |
| Ghersin, T | 1 |
| Joachims, HZ | 1 |
| Westerman, ST | 1 |
| Gilbert, LM | 1 |
| Netzer, A | 1 |
| Reiss, M | 1 |
| Lancaster, JL | 1 |
| Mortimore, S | 1 |
| McCormick, M | 1 |
| Hart, CA | 1 |
| Meyerhoff, WL | 1 |
| Gates, GA | 1 |
| Montalbo, PJ | 1 |
| Badré, R | 1 |
| Guillerm, R | 1 |
| Mouel, C | 1 |
| Poiret, F | 1 |
| Wagner, WH | 1 |
| Federspil, P | 1 |
| Lin, RG | 1 |
| Arcala, AE | 1 |
| Esposito, S | 1 |
| Noviello, S | 1 |
| D'Errico, G | 1 |
| Montanaro, C | 1 |
| Crowther, JA | 1 |
| Simpson, D | 1 |
| Baker, RS | 1 |
| Chole, RA | 1 |
| Browning, GG | 1 |
| Gatehouse, S | 1 |
| Calder, IT | 1 |
| Sambe, B | 1 |
| Murakami, H | 1 |
| Kobayasi, K | 1 |
| Jo, K | 1 |
| Inafuku, S | 1 |
| von Graevenitz, A | 1 |
| Carrington, GO | 1 |
| Riff, LJ | 1 |
| McCracken, GH | 1 |
| Eichenwald, HF | 1 |
| Washington, JA | 1 |
| Weichselbaumer, W | 1 |
| Majkus, V | 2 |
| Horáková, Z | 1 |
| Výmola, F | 1 |
| Stol, M | 1 |
| Vacek, V | 1 |
| Stafová, J | 1 |
| Sýkorová, L | 1 |
2 reviews available for gentamicin and Middle Ear Inflammation
| Article | Year |
|---|---|
Chemotherapy in ear disease.
Topics: Acute Disease; Child; Child, Preschool; Chlorpheniramine; Chronic Disease; Ear, Middle; Enterobacter | 1972 |
Antimicrobiol therapy: therapeutic recommendations and a review of newer drugs. Part I. Therapy of infectious conditions.
Topics: Adolescent; Ampicillin; Anti-Bacterial Agents; Arthritis, Infectious; Bacteroides Infections; Brain | 1974 |
7 trials available for gentamicin and Middle Ear Inflammation
| Article | Year |
|---|---|
A randomised controlled trial of active chronic otitis media comparing courses of eardrops versus one-off topical treatments suitable for primary, secondary and tertiary healthcare settings.
Topics: Acetic Acid; Administration, Topical; Adult; Analysis of Variance; Anti-Infective Agents; Audiometry | 2012 |
The weeping ear: clinical re-evaluation of treatment.
Topics: Adult; Bacterial Infections; Chronic Disease; Clinical Trials as Topic; Colistin; Double-Blind Metho | 1982 |
[Multicenter study comparing the efficacy and tolerance of topical ciprofloxacin (0.3%) versus topical gentamicin (0.3%) in the treatment of simple, non-cholesteatomaous chronic otitis media in the suppurative phase].
Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Bacterial Agents; Aspergillus; Candida albica | 1995 |
Topical ciprofloxacin vs intramuscular gentamicin for chronic otitis media.
Topics: Administration, Topical; Adult; Chronic Disease; Ciprofloxacin; Female; Gentamicins; Humans; Injecti | 1992 |
Medical treatment of chronic otitis media: steroid or antibiotic with steroid ear-drops?
Topics: Betamethasone; Chronic Disease; Drug Combinations; Evaluation Studies as Topic; Female; Gentamicins; | 1991 |
A randomized clinical trial of topical gentamicin after tympanostomy tube placement.
Topics: Administration, Topical; Adolescent; Adult; Age Factors; Aged; Child; Child, Preschool; Clinical Tri | 1988 |
Medical management of active chronic otitis media: a controlled study.
Topics: Administration, Oral; Administration, Topical; Adult; Aged; Chronic Disease; Clinical Trials as Topi | 1988 |
30 other studies available for gentamicin and Middle Ear Inflammation
| Article | Year |
|---|---|
Intratympanic Lipopolysaccharide Elevates Systemic Fluorescent Gentamicin Uptake in the Cochlea.
Topics: Animals; Cochlea; Cytokines; Disease Models, Animal; Gentamicins; Injection, Intratympanic; Lipopoly | 2021 |
Brainstem auditory evoked responses in 37 dogs with otitis media before and after topical therapy.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Dogs; Ear, Middle; Evoked Potentials, Audit | 2018 |
Auditory and Histopathological Effects of Topical Mercurochrome Treatment in Rats with Tympanic Membrane Perforation.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Cochlea; Female; Gentamicins; Hearing; Merb | 2019 |
NOD2/RICK-dependent β-defensin 2 regulation is protective for nontypeable Haemophilus influenzae-induced middle ear infection.
Topics: Animals; beta-Defensins; Cell Line; Cytoplasm; Ear, Middle; Endocytosis; Gene Expression Regulation; | 2014 |
Myeloid differentiation primary response gene 88 is required for the resolution of otitis media.
Topics: Animals; Anti-Bacterial Agents; Ear, Middle; Gene Expression Regulation; Gentamicins; Haemophilus In | 2008 |
[Lemierre syndrome: a complication of an oropharyngeal infection].
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; Cefotax | 2008 |
Gentamicin tympanoclysis: effects on the labyrinthine sensory cells.
Topics: Acoustic Maculae; Animals; Anti-Bacterial Agents; Ataxia; Cats; Ear, Middle; Gentamicins; Hair Cells | 2003 |
Dexamethasone does not alter in vitro antibacterial efficacy of gentamicin.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Dexamethasone; Drug Administration Schedule; Gentam | 2007 |
Bacterial isolates from chronic discharging ears in Nigerian children.
Topics: Adolescent; Child; Child, Preschool; Chronic Disease; Drug Resistance, Microbial; Female; Gentamicin | 1983 |
Clindamycin in treatment of chronic recurrent suppurative otitis media in children.
Topics: Bacteria; Child; Child, Preschool; Chronic Disease; Clindamycin; Drug Administration Schedule; Femal | 1980 |
Inhibition of proteases in Pseudomonas otitis media in chinchillas.
Topics: Animals; Anti-Bacterial Agents; Chinchilla; Dipeptides; Disease Models, Animal; Gentamicins; Otitis | 1996 |
Do aminoglycoside otic preparations cause ototoxicity in the presence of tympanic membrane perforations?
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Ear, Inner; Female; Gentamicins; Hearin | 1997 |
Sustained release of antibiotic from a fibrin-gelatin-antibiotic mixture.
Topics: Administration, Topical; Ampicillin; Anti-Bacterial Agents; Bacillus subtilis; Delayed-Action Prepar | 1997 |
Prophylactic treatment after ventilation tube insertion: comparison of various methods.
Topics: Administration, Oral; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Age | 1998 |
[When do ear drops help, when are they harmful?].
Topics: Administration, Topical; Chloramphenicol; Contraindications; Drug-Related Side Effects and Adverse R | 1999 |
Systemic absorption of gentamicin in the management of active mucosal chronic otitis media.
Topics: Absorption; Adult; Anti-Bacterial Agents; Chronic Disease; Female; Gentamicins; Humans; Male; Otitis | 1999 |
Anaerobic isolates in chronic recurrent suppurative otitis media. Treatment with carbenicillin alone and in combination with gentamicin.
Topics: Adolescent; Anaerobiosis; Bacteria; Bacteroides fragilis; Carbenicillin; Child; Child, Preschool; Dr | 1979 |
Pseudomonas mastoiditis.
Topics: Adult; Aged; Carbenicillin; Colistin; Diabetes Mellitus; Female; Gentamicins; Humans; Infant; Male; | 1977 |
[Experimental results and use of the manosonic aerosoliser (U.D.V.) for the treatment of middle-ear and affections (author's transl)].
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Evaluation Studies as Topic; Female; Gentamicins; | 1978 |
[Special problems in the chemotherapy of bacterial infections in otolaryngology (author's transl)].
Topics: Aminoglycosides; Bacterial Infections; Ear; Gentamicins; Humans; Kanamycin; Neomycin; Otitis Media; | 1977 |
When the weeping stopped: an otologist views otorrhea and gentamicin.
Topics: Administration, Topical; Chronic Disease; Gentamicins; Hearing; Myringoplasty; Otitis Externa; Otiti | 1976 |
[Ototoxicity of the aminoglycoside antibiotics (author's transl)].
Topics: Acid Phosphatase; Alkaline Phosphatase; Amikacin; Animals; Anti-Bacterial Agents; Child; Ear, Inner; | 1976 |
Fusobacterium septicemia with otitis media and mastoiditis.
Topics: Bacterial Infections; Drainage; Female; Fusobacterium; Gentamicins; Humans; Infant; Mastoid; Mastoid | 1975 |
[Treatment of otorhinolaryngological infections with BB-K8 (author's transl)].
Topics: Acute Disease; Adult; Child; Child, Preschool; Female; Gentamicins; Humans; Infant; Kanamycin; Male; | 1974 |
Halophilic vibrios from extraintestinal lesions in man.
Topics: Accidents, Aviation; Adult; Aged; Cephalothin; Erythromycin; Female; Gallbladder Diseases; Gangrene; | 1973 |
Aeromonas hydrophila in clinical bacteriologic specimens.
Topics: Aeromonas; Bacterial Infections; Blood; Gentamicins; Humans; Otitis Media; Postoperative Complicatio | 1972 |
[Surgical therapy of Pseudomonas aeruginosa infections in chronic otitis media].
Topics: Adult; Female; Gentamicins; Humans; Male; Middle Aged; Otitis Media; Preoperative Care; Pseudomonas | 1971 |
Employment of hydron polymer antibiotic vehicle in otolaryngology.
Topics: Acrylates; Animals; Anti-Bacterial Agents; Bacitracin; Biological Assay; Chloramphenicol; Colistin; | 1969 |
[Clinical experience with gentamicin in resistant gramnegative infections].
Topics: Adolescent; Adult; Female; Gentamicins; Humans; Infant; Infections; Male; Middle Aged; Otitis Media; | 1970 |
[The use of glycolmetacrylate-gel saturated with antibiotics in tympanoplasty].
Topics: Acrylates; Anti-Bacterial Agents; Bacitracin; Chloramphenicol; Chronic Disease; Colistin; Gels; Gent | 1970 |