gentamicin has been researched along with Meniere Disease in 335 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Meniere Disease: A disease of the inner ear (LABYRINTH) that is characterized by fluctuating SENSORINEURAL HEARING LOSS; TINNITUS; episodic VERTIGO; and aural fullness. It is the most common form of endolymphatic hydrops.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intra tympanic gentamicin is more effective in controlling tinnitus as compared to dexamethasone and placebo and there was no marked difference in control of tinnitus between placebo and steroids." | 9.24 | Short Term Results of Intra Tympanic Gentamicin and Dexamethasone on Hearing and Tinnitus in Meniere's disease: A Case Control Study. ( Shamas, IU, 2017) |
| "Intratympanic application of gentamicin is a relatively safe and efficient treatment for the reduction of complaints of vertigo attacks associated with Menière's disease." | 9.13 | Intratympanic gentamicin therapy for control of vertigo in unilateral Menire's disease: a prospective, double-blind, randomized, placebo-controlled trial. ( Albers, FW; Kingma, CM; Postema, RJ; Van Der Laan, BF; Wit, HP, 2008) |
| " Intratympanic gentamicin (ITG) was superior to intratympanic steroid (ITS) in reducing the number of vertigo attacks (odds ratio (OR) 3." | 9.12 | What is the efficacy of gentamicin on the incidence of vertigo attacks and hearing in patients with Meniere's disease compared with steroids? A meta-analysis. ( Jiang, M; Zhang, Z; Zhao, C, 2021) |
| "We investigated the effect of intratympanic gentamicin and dexamethasone treatments on the control of vertigo and hearing loss in patients with Meniere's disease." | 9.12 | [Intratympanic treatment in Meniere's disease: the effect of gentamicin and dexamethasone on vertigo control and hearing]. ( Akkuzu, B; Ozgirgin, N; Ozlüoğlu, LN, 2006) |
| "To determine if a protocol of weekly intratympanic gentamicin injections administered until development of signs of unilateral vestibular hypofunction can alleviate vertigo while preserving hearing in patients with intractable vertigo caused by unilateral Meniere's disease." | 9.09 | Intratympanic gentamicin for control of vertigo in Meniere's disease: vestibular signs that specify completion of therapy. ( Minor, LB, 1999) |
| "The objective of this study was to examine the effect of intratympanically applied gentamicin (GM) (30 mg/mL) on hearing and tinnitus in patients with intractable Meniere's disease." | 9.09 | Effect of intratympanic gentamicin on hearing and tinnitus in Meniere's disease. ( Aalto, H; Eklund, S; Ishizaki, H; Pyykkö, I; Vasama, JP, 1999) |
| "To assess the effectiveness of intratympanic gentamicin in the treatment of vertigo in Ménière's disease." | 8.87 | Intratympanic gentamicin for Ménière's disease or syndrome. ( Pullens, B; van Benthem, PP, 2011) |
| "Titration therapy with intratympanic gentamicin offers class A or B control of vertigo in 87% (range, 75%-100%) of patients with unilateral Ménière's disease." | 8.82 | Intratympanic gentamicin for the treatment of Meniere's disease and other forms of peripheral vertigo. ( Carey, J, 2004) |
| "To describe the long-term clinical vertigo control along with measured lateral canal vestibular function in patients with unilateral refractory Menière's disease (MD) treated with gentamicin transtympanic injections (TTI)." | 7.91 | Long-term Vertigo Control and Vestibular Function After Low-dose On-demand Transtympanic Gentamicin for Refractory Menière's Disease. ( Deguine, O; Fraysse, B; Fraysse, ME; Kmeid, M; Mansour, C; Marx, M; Nicolas, S, 2019) |
| "Perilymph gentamicin concentrations and correlation with endolymphatic hydrops in an animal model were assessed." | 7.88 | Gentamicin delivery to the inner ear: Does endolymphatic hydrops matter? ( Duan, M; Marques, P; Perez-Fernandez, N; Spratley, J, 2018) |
| "To verify the hypothesis that intratympanic (IT) gentamicin (Gent) treatment in Ménière's disease (MD) is capable of reducing endolymphatic hydrops (EH), as evaluated by 3-dimensional fluid-attenuated inversion recovery (3D-FLAIR) sequence in a 3-Tesla magnetic resonance imaging (MRI) unit, after IT gadolinium administration." | 7.78 | Magnetic resonance imaging fails to show evidence of reduced endolymphatic hydrops in gentamicin treatment of Ménière's disease. ( Barbieri, F; Beltramello, A; Fiorino, F; Pizzini, FB, 2012) |
| "To compare the cochlear distribution of low-dose fluorescent gentamicin after intra-tympanic administration in guinea pig (GPs) with clinical data of low dose intra-tympanic gentamicin in patients with intractable vertigo." | 7.76 | Evidence-based modification of intratympanic gentamicin injections in patients with intractable vertigo. ( Dai, CF; Liu, JP; Steyger, PS; Wang, Q; Zhai, F, 2010) |
| "To compare proportions of the combined outcome of vertigo control and hearing preservation between intratympanic gentamicin injections and endolymphatic sac shunt surgery for intractable vertigo in Ménière's disease patients." | 7.76 | Outcomes of endolymphatic shunt surgery for Ménière's disease: comparison with intratympanic gentamicin on vertigo control and hearing loss. ( Berliner, K; Chung, J; Derebery, MJ; Fisher, LM; Green, K, 2010) |
| "The aim of this study was to correlate long-term vertigo control with reduction in vestibular function after intratympanic (IT) gentamicin therapy for unilateral Ménière's disease." | 7.75 | Vestibular function and vertigo control after intratympanic gentamicin for Ménière's disease. ( Carey, JP; Della Santina, CC; Minor, LB; Nguyen, KD, 2009) |
| "This retrospective study reports the overall efficacy and comparative results of intratympanic gentamicin injections for disabling vertigo episodes." | 7.74 | Gentamicin injections for Ménière disease: comparison of subjective and objective end points. ( Cronin, GW; Hardin, RB; Steenerson, RL, 2008) |
| "To assess long-term vertigo symptom control in patients after intratympanic gentamicin instillation for incapacitating unilateral Ménière's disease." | 7.74 | Long-term vertigo control in patients after intratympanic gentamicin instillation for Ménière's disease. ( Alexander, A; Bodmer, D; Chen, JM; Morong, S; Nedzelski, JM; Stewart, C, 2007) |
| "The objective of our study was to determine whether angular vestibulo-ocular reflex (aVOR) gains correlated with vertigo control after intratympanic gentamicin treatment for Meniere's disease." | 7.73 | Angular vestibulo-ocular reflex gains correlate with vertigo control after intratympanic gentamicin treatment for Meniere's disease. ( Carey, JP; Haslwanter, T; Lin, FR; Migliaccio, AA; Minor, LB, 2005) |
| "To look for factors relating to the vertigo control and hearing changes after intratympanic injections of gentamicin (GM)." | 7.73 | Factors relating to the vertigo control and hearing changes following intratympanic gentamicin for intractable Ménière's disease. ( Fukushima, M; Horii, A; Kitahara, T; Kizawa, K; Kubo, T; Masumura, C; Mitani, K; Nakagawa, A; Nishiike, S; Nishimura, M; Saika, T; Sasaki, T; Uno, A, 2006) |
| "To determine the incidence, extent, and time course of hearing loss following instillation of intratympanic gentamicin using a predetermined fixed protocol for incapacitating unilateral Meniere's disease and to determine whether such loss is associated with any identifiable risk factors." | 7.71 | Hearing loss following intratympanic instillation of gentamicin for the treatment of unilateral Meniere's disease. ( Al-Abidi, A; Chen, JM; Kaplan, DM; Nedzelski, JM; Shipp, DB, 2002) |
| "Intratympanic gentamicin is used to control dizziness of Ménière's disease, with a low rate of morbidity and a high success rate." | 7.70 | Low-dose intratympanic gentamicin treatment for dizziness in Ménière's disease. ( Longridge, NS; Mallinson, AI, 2000) |
| "We have examined the effect of intratympanic gentamicin on hearing and tinnitus in 69 patients with intractable Menière's disease." | 7.69 | Effect of intratympanically administered gentamicin on hearing and tinnitus in Menière's disease. ( Aalto, H; Ishizaki, H; Kaasinen, S; Pyykkö, I, 1995) |
| "Vertigo attacks in most cases of Meniere's disease (MD) are successfully treated with lifestyle changes and medication." | 5.40 | Intratympanic gentamicin as a treatment for drop attacks in patients with Meniere's disease. ( Bahmad, F; Rauch, SD; Viana, LM, 2014) |
| "Treatment of drop attacks is still a matter of discussion; most cases have a benign course with spontaneous remission and no treatment is necessary." | 5.33 | Drop attacks and vertical vertigo after transtympanic gentamicin: diagnosis and management. ( Bignami, M; Bruschini, L; Casani, AP; Dallan, I; Nacci, A, 2005) |
| "Of these, 68 patients had Meniere's disease; 4 patients had recurrent vertigo after endolymphatic sac surgery and were followed for at least 1 year." | 5.31 | Intratympanic gentamicin therapy for persistent vertigo after endolymphatic sac surgery. ( Leonetti, JP; Marzo, SJ, 2002) |
| "Tinnitus is a very serious problem in otolaryngology." | 5.28 | [Treatment of tinnitus with gentamicin]. ( Kucera, P; Novotný, M, 1990) |
| "Intra tympanic gentamicin is more effective in controlling tinnitus as compared to dexamethasone and placebo and there was no marked difference in control of tinnitus between placebo and steroids." | 5.24 | Short Term Results of Intra Tympanic Gentamicin and Dexamethasone on Hearing and Tinnitus in Meniere's disease: A Case Control Study. ( Shamas, IU, 2017) |
| " We concluded that intratympanic gentamicin may improve the control of vertigo, and result in little or no difference to tinnitus, but the certainty of the evidence is low." | 5.22 | Intratympanic gentamicin compared with placebo for Ménière's disease. ( de Amesti, F; Santander, MJ; Winter, M, 2022) |
| "Background The intratympanic application of the ototoxic aminoglycoside gentamicin has shown promising results as an ablative treatment for vertigo associated with Ménière's disease." | 5.22 | The effect of intratympanic gentamicin for treatment of Ménière's disease on lower frequency hearing. ( Becker, M; Chung, DW; Sam, G; van der Hoeven, R; Verweij, S, 2016) |
| "Intratympanic application of gentamicin is a relatively safe and efficient treatment for the reduction of complaints of vertigo attacks associated with Menière's disease." | 5.13 | Intratympanic gentamicin therapy for control of vertigo in unilateral Menire's disease: a prospective, double-blind, randomized, placebo-controlled trial. ( Albers, FW; Kingma, CM; Postema, RJ; Van Der Laan, BF; Wit, HP, 2008) |
| " Intratympanic gentamicin (ITG) was superior to intratympanic steroid (ITS) in reducing the number of vertigo attacks (odds ratio (OR) 3." | 5.12 | What is the efficacy of gentamicin on the incidence of vertigo attacks and hearing in patients with Meniere's disease compared with steroids? A meta-analysis. ( Jiang, M; Zhang, Z; Zhao, C, 2021) |
| "We investigated the effect of intratympanic gentamicin and dexamethasone treatments on the control of vertigo and hearing loss in patients with Meniere's disease." | 5.12 | [Intratympanic treatment in Meniere's disease: the effect of gentamicin and dexamethasone on vertigo control and hearing]. ( Akkuzu, B; Ozgirgin, N; Ozlüoğlu, LN, 2006) |
| "To determine if a protocol of weekly intratympanic gentamicin injections administered until development of signs of unilateral vestibular hypofunction can alleviate vertigo while preserving hearing in patients with intractable vertigo caused by unilateral Meniere's disease." | 5.09 | Intratympanic gentamicin for control of vertigo in Meniere's disease: vestibular signs that specify completion of therapy. ( Minor, LB, 1999) |
| "The objective of this study was to examine the effect of intratympanically applied gentamicin (GM) (30 mg/mL) on hearing and tinnitus in patients with intractable Meniere's disease." | 5.09 | Effect of intratympanic gentamicin on hearing and tinnitus in Meniere's disease. ( Aalto, H; Eklund, S; Ishizaki, H; Pyykkö, I; Vasama, JP, 1999) |
| "We evaluated the hypothesis that topical intratympanic gentamicin can relieve the vertigo of disabling Menière's disease, reduce or ablate vestibular caloric excitability, and preserve hearing." | 5.07 | Treatment of Menière's disease with topical gentamicin: a preliminary report. ( Bryce, GE; Nedzelski, JM; Pfleiderer, AG, 1992) |
| "To assess the effectiveness of intratympanic gentamicin in the treatment of vertigo in Ménière's disease." | 4.87 | Intratympanic gentamicin for Ménière's disease or syndrome. ( Pullens, B; van Benthem, PP, 2011) |
| "To assess and summarize the best available evidence for the use of intratympanic gentamicin in patients with Meniere's disease with respect to improvement of vertigo, tinnitus, and change in hearing." | 4.82 | Systematic review of intratympanic gentamicin in Meniere's disease. ( Diamond, C; Hornig, JD; Liu, R; O'Connell, DA, 2003) |
| "Inclusion criteria to select articles for meta-analysis were clear description of gentamicin delivery technique, clearly reported vertigo control results, and report of hearing loss posttreatment." | 4.82 | Intratympanic gentamicin therapy for Ménière's disease: a meta-analysis. ( Anderson, JP; Chia, SH; Gamst, AC; Harris, JP, 2004) |
| "The use of gentamicin perfusion in the management of Meniere disease with intractable vertigo has been demonstrated to have a very high rate of success, and is much less invasive than alternative surgical procedures such as vestibular nerve section or labyrinthectomy." | 4.82 | Transtympanic perfusion: indications and limitations. ( Light, JP; Silverstein, H, 2004) |
| "Titration therapy with intratympanic gentamicin offers class A or B control of vertigo in 87% (range, 75%-100%) of patients with unilateral Ménière's disease." | 4.82 | Intratympanic gentamicin for the treatment of Meniere's disease and other forms of peripheral vertigo. ( Carey, J, 2004) |
| "At least 11 articles have been published that indicate that intratympanic gentamicin treatments control vertigo well and provide acceptable rates of hearing loss." | 4.79 | Clinical forum: a review of intratympanic therapy. ( Blakley, BW, 1997) |
| "Ménière's disease (MD), characterized by episodic vertigo attacks and fluctuating progressive hearing loss, is treated by low-dose intratympanic gentamicin (ITG) injections." | 4.02 | Intratympanic gentamicin injection for refractory ménière's disease (MD) has potential effect in preventing contralateral MD occurrence. ( Dai, C; Song, Z; Wang, J; Wu, Y; Yu, J; Zhou, Y, 2021) |
| " Special attention should be paid to the role of dietary restrictions for glucose in patients with Meniere's disease, as there is a strong evidence about the presence of insulin receptors in the saccule, the main structure affected by pathological changes due to endolymphatic hydrops; to the possible use of endogenous antisecretory factor administered in specially processed cereals; and to the effects of low-dose intratympanic gentamicin, especially in patients with intractable Meniere's disease." | 3.96 | Letter to Editor concerning the "Therapeutic strategies in the treatment of Meniere's disease: the Italian Experience". ( Cassandro, C; Cassandro, E; De Luca, P; Gioacchini, FM; Ralli, M; Savignano, L; Scarpa, A, 2020) |
| "The aims of the present study are to investigate the variations in clinical features, including medical history, hearing function, vestibular function, and degree of endolymphatic hydrops (EH), in Meniere's disease (MD) patients with and without drop attacks (DAs), and to examine the efficacy of intratympanic gentamicin (ITG) treatment in alleviating DAs." | 3.91 | Clinical features and management of Meniere's disease patients with drop attacks. ( Dai, C; Li, X; Sha, Y; Wu, Q, 2019) |
| "To describe the long-term clinical vertigo control along with measured lateral canal vestibular function in patients with unilateral refractory Menière's disease (MD) treated with gentamicin transtympanic injections (TTI)." | 3.91 | Long-term Vertigo Control and Vestibular Function After Low-dose On-demand Transtympanic Gentamicin for Refractory Menière's Disease. ( Deguine, O; Fraysse, B; Fraysse, ME; Kmeid, M; Mansour, C; Marx, M; Nicolas, S, 2019) |
| "To determine whether long term (>48 months) symptomatic vertigo control is sustained in patients with Menière's disease from a previous comparative trial of intratympanic methylprednisolone versus gentamicin, and if the two treatments remain nonsignificantly different at long-term follow-up." | 3.91 | Long-Term Follow-Up of Intratympanic Methylprednisolone Versus Gentamicin in Patients With Unilateral Menière's Disease. ( Agarwal, K; Bronstein, AM; Golding, JF; Harcourt, JP; Lambert, A; Patel, M; Wong, PY, 2019) |
| "In the last 4 years the authors observed a trend that correcting vitamin D deficiency in newly diagnosed cases of Meniere's disease decreased the necessity of the ablative therapy with intratympanic gentamicin." | 3.88 | Vitamin D supplementation may improve symptoms in Meniere's disease. ( Büki, B; Jünger, H; Lundberg, YW, 2018) |
| "Perilymph gentamicin concentrations and correlation with endolymphatic hydrops in an animal model were assessed." | 3.88 | Gentamicin delivery to the inner ear: Does endolymphatic hydrops matter? ( Duan, M; Marques, P; Perez-Fernandez, N; Spratley, J, 2018) |
| "To compare the efficacy of intratympanic gentamicin injection (ITG) on vertigo control, drop attacks, and functional level in Menière's disease patients with and without a history of migraine." | 3.85 | Efficacy of Intratympanic Gentamicin in Menière's Disease With and Without Migraine. ( Liu, YF; Rauch, SD; Renk, E; Xu, HX, 2017) |
| " Further repeated ITD courses or intratympanic gentamicin (ITG) were given if the vertigo was not satisfactorily controlled." | 3.83 | Intratympanic steroids injection is effective for the treatment of drop attacks with Ménière's disease and delayed endolymphatic hydrops: A retrospective study. ( Kong, WJ; Leng, Y; Liu, B; Liu, D; Liu, J; Zhang, SL; Zhou, R, 2016) |
| "1) To evaluate the efficacy of, and problems with, intratympanic gentamicin injection (ITG) in medically intractable definite Ménière's disease (MD) and secondary endolymphatic hydrops (EH); and 2) to review the vestibular status and treatment options of intractable vertigo even after ITG." | 3.81 | Management of intractable Ménière's disease after intratympanic injection of gentamicin. ( Choi, BY; Han, JJ; Koo, JW; Park, J; Rah, YC, 2015) |
| "In recent years, several titration or on-demand protocols using low-dose repeated intratympanic (IT) gentamicin injections have been adopted for the vertigo control in unilateral medical refractory Menière's disease (MD)." | 3.80 | Intratympanic gentamicin treatment 'as needed' for Meniere's disease. Long-term analysis using the Kaplan-Meier method. ( Benazzo, M; Gatti, O; Manfrin, M; Mira, E; Quaglieri, S; Rebecchi, E; Tinelli, C, 2014) |
| "Round window hyaluronic acid pledget technique used as a sustained delivery vehicle for intratympanic gentamicin treatment for Ménière's disease produces similar rates of vertigo control compared with other techniques but a greater risk of hearing loss." | 3.80 | Middle ear gentamicin-soaked pledgets in the treatment of Ménière's disease. ( Bottrill, ID; MacKeith, SA; Mawby, T; Whiteside, OJ, 2014) |
| "To verify the hypothesis that intratympanic (IT) gentamicin (Gent) treatment in Ménière's disease (MD) is capable of reducing endolymphatic hydrops (EH), as evaluated by 3-dimensional fluid-attenuated inversion recovery (3D-FLAIR) sequence in a 3-Tesla magnetic resonance imaging (MRI) unit, after IT gadolinium administration." | 3.78 | Magnetic resonance imaging fails to show evidence of reduced endolymphatic hydrops in gentamicin treatment of Ménière's disease. ( Barbieri, F; Beltramello, A; Fiorino, F; Pizzini, FB, 2012) |
| "Patients with stage 1 Ménière's disease appear to have similar vertigo control with better hearing preservation than patients with advanced disease when treated with low-dose intratympanic gentamicin (10 mg/mL)." | 3.76 | Intratympanic gentamicin treatment of patients with Ménière's disease with normal hearing. ( Alameda, YA; Daugherty, J; Silverstein, H; Van Ess, MJ; Wazen, J, 2010) |
| "To compare the cochlear distribution of low-dose fluorescent gentamicin after intra-tympanic administration in guinea pig (GPs) with clinical data of low dose intra-tympanic gentamicin in patients with intractable vertigo." | 3.76 | Evidence-based modification of intratympanic gentamicin injections in patients with intractable vertigo. ( Dai, CF; Liu, JP; Steyger, PS; Wang, Q; Zhai, F, 2010) |
| "To compare proportions of the combined outcome of vertigo control and hearing preservation between intratympanic gentamicin injections and endolymphatic sac shunt surgery for intractable vertigo in Ménière's disease patients." | 3.76 | Outcomes of endolymphatic shunt surgery for Ménière's disease: comparison with intratympanic gentamicin on vertigo control and hearing loss. ( Berliner, K; Chung, J; Derebery, MJ; Fisher, LM; Green, K, 2010) |
| "Transtympanic gentamicin therapy via the Silverstein MicroWick results in good vertigo control." | 3.75 | Transtympanic gentamicin treatment using Silverstein MicroWick in Ménière's disease patients: long term outcome. ( O'Sullivan, G; Srinivasan, VR; Suryanarayanan, R, 2009) |
| "Intratympanic gentamicin perfusion provides effective control of vertigo in patients with Ménière's disease." | 3.75 | Hearing results following intratympanic gentamicin perfusion for Ménière's disease. ( Aidonis, I; Kyrodimos, E; Sismanis, A, 2009) |
| "In Ménière's disease (MD), when patients have incapacitating vertigo that is resistant to drug treatment, an intratympanic gentamicin application (ITG) is often proposed." | 3.75 | Tenotomy of the tensor tympani and stapedius tendons in Ménière's disease. ( De Valck, CF; Van de Heyning, PH; Van Rompaey, V; Wuyts, EL, 2009) |
| "Administration of high-dose gentamicin for intractable Meniere's disease appears to be effective in achieving long-term control of vertigo." | 3.75 | High-dose intratympanic gentamicin instillations for treatment of Meniere's disease: long-term results. ( Hsieh, LC; Ko, YC; Lin, HC; Lin, LH; Shu, MT; Tsai, HT, 2009) |
| "The aim of this study was to correlate long-term vertigo control with reduction in vestibular function after intratympanic (IT) gentamicin therapy for unilateral Ménière's disease." | 3.75 | Vestibular function and vertigo control after intratympanic gentamicin for Ménière's disease. ( Carey, JP; Della Santina, CC; Minor, LB; Nguyen, KD, 2009) |
| "This retrospective study reports the overall efficacy and comparative results of intratympanic gentamicin injections for disabling vertigo episodes." | 3.74 | Gentamicin injections for Ménière disease: comparison of subjective and objective end points. ( Cronin, GW; Hardin, RB; Steenerson, RL, 2008) |
| "To describe the histopathology and morphometry of the vestibular end organs from a 59-year-old Meniere's patient who underwent transmastoid labyrinthectomy for recurrent vertigo after failed intratympanic gentamicin." | 3.74 | Histopathology of the vestibular end organs after intratympanic gentamicin failure for Meniere's disease. ( Baloh, RW; Ishiyama, A; Ishiyama, G; Lopez, I, 2007) |
| "To assess long-term vertigo symptom control in patients after intratympanic gentamicin instillation for incapacitating unilateral Ménière's disease." | 3.74 | Long-term vertigo control in patients after intratympanic gentamicin instillation for Ménière's disease. ( Alexander, A; Bodmer, D; Chen, JM; Morong, S; Nedzelski, JM; Stewart, C, 2007) |
| "The aim of this study was to verify the efficacy of a modified Odkvist titration protocol of intratympanic gentamicin application in the control of vertigo attacks and the effects on the auditory and vestibular function in a group of 71 patients affected by monolateral MD resistant to medical therapy." | 3.73 | Intratympanic gentamicin in monolateral Meniere's disease: our experience. ( Bertino, G; Casati, L; Durso, D; Manfrin, M; Mira, E, 2006) |
| "To determine the long-term hearing and vestibular outcomes in patients with intractable vertigo caused by unilateral Meniere's disease, who were treated with transtympanic injection of gentamicin." | 3.73 | [Long-term results of transtympanic gentamicin treatment in Meniere's disease]. ( Bartoszewicz, R; Kowalska, M; Krzeska-Malinowska, I; Niemczyk, K; Pierchała, K, 2005) |
| "The objective of our study was to determine whether angular vestibulo-ocular reflex (aVOR) gains correlated with vertigo control after intratympanic gentamicin treatment for Meniere's disease." | 3.73 | Angular vestibulo-ocular reflex gains correlate with vertigo control after intratympanic gentamicin treatment for Meniere's disease. ( Carey, JP; Haslwanter, T; Lin, FR; Migliaccio, AA; Minor, LB, 2005) |
| "Interval treatment with up to three intratympanic gentamicin injections once weekly effectively controlled vertigo while preserving hearing in patients with Ménière's disease and recurrent or resistant vertigo after saccotomy." | 3.73 | Intratympanic gentamicin treatment after endolymphatic sac surgery. ( Gouveris, H; Lange, G; Mann, WJ, 2005) |
| "To look for factors relating to the vertigo control and hearing changes after intratympanic injections of gentamicin (GM)." | 3.73 | Factors relating to the vertigo control and hearing changes following intratympanic gentamicin for intractable Ménière's disease. ( Fukushima, M; Horii, A; Kitahara, T; Kizawa, K; Kubo, T; Masumura, C; Mitani, K; Nakagawa, A; Nishiike, S; Nishimura, M; Saika, T; Sasaki, T; Uno, A, 2006) |
| "Intratympanic gentamicin treatment ought to be offered to Ménière's patients suffering from disabling vertigo, with the proviso that they be made aware of the possibility of hearing deterioration." | 3.73 | Intratympanic gentamicin treatment in Meniere's disease: patients' experiences and outcomes. ( Prinsley, PR; Sandooram, D; Smith, WK, 2006) |
| "Gentamicin solution at concentrations of either 30 or 3 mg/mL was infused daily into the left middle ear of adult cats until overt ataxia occurred." | 3.72 | Gentamicin tympanoclysis: effects on the labyrinthine sensory cells. ( Pender, DJ, 2003) |
| "To determine the long-term hearing outcome in patients with intractable vertigo caused by unilateral Ménière's disease who were treated with intratympanic injection of gentamicin." | 3.72 | Long-term hearing outcome in patients receiving intratympanic gentamicin for Ménière's disease. ( Minor, LB; Wu, IC, 2003) |
| "Intratympanic gentamicin is an accepted mode of treatment for patients with Meniere's disease who suffer from recurrent vertigo attacks in spite of conservative medical treatment." | 3.72 | [Intratympanic gentamicin treatment for intractable Menière's disease]. ( Gilony, D; Kronenberg, J; Wolf, M, 2004) |
| "Vestibular nerve section and transtympanic gentamicin administration are procedures with proven efficacy in the treatment of vertigo associated with Meniere's disease refractory to medical management." | 3.72 | Vestibular nerve section versus intratympanic gentamicin for Meniere's disease. ( Arriaga, MA; Chen, DA; Hillman, TA, 2004) |
| "To investigate the effect and toxicity of intratympanic gentamicin injection therapy for intractable vertigo of Menière's disease." | 3.72 | [Intratympanic gentamicin in Menière's disease]. ( Gao, B; Huang, W; Xu, H, 2004) |
| "Intratympanic or round window application of gentamicin is often used to alleviate disabling vertigo arising from unilateral Meniere's disease; however, treatment is often accompanied by hearing loss because the drug initially enters the cochlea before diffusing to the vestibular system." | 3.72 | Vestibular destruction by slow infusion of gentamicin into semicircular canals. ( Ding, D; Lii, M; Salvi, R; Zheng, XY, 2004) |
| "It was concluded that increasing the gentamicin concentration to 40 mg/ml probably produces similar rates of vertigo control as those of the lower dose, at least initially, but requires fewer injections." | 3.71 | Efficacy of increased gentamicin concentration for intratympanic injection therapy in Ménière's disease. ( Abou-Halawa, AS; Poe, DS, 2002) |
| "It appears that a single transtympanic gentamicin injection is effective in controlling the vertigo of Ménière's syndrome." | 3.71 | Long-term follow-up of transtympanic gentamicin for Ménière's syndrome. ( Beatty, CW; Driscoll, CL; Facer, GW; Harner, SG; McDonald, TJ, 2001) |
| " There was no difference in general quality of life, present hearing loss, or tinnitus between the three treatment groups, but the gentamicin-treated patients had less vertigo than did the other groups." | 3.71 | Patients' subjective evaluations of quality of life related to disease-specific symptoms, sense of coherence, and treatment in Ménière's disease. ( Bagger-Sjöbäck, D; Bergenius, J; Langius, A; Söderman, AC; Tjell, C, 2001) |
| "On the basis of an average 10-month follow-up period, of the methods currently available to treat Meniere's patients with gentamicin, low-flow CGT seems to provide an excellent combination of vertigo control and tinnitus and pressure improvement, with a relatively low risk to hearing and vestibular function." | 3.71 | Continuous gentamicin therapy using an IntraEAR microcatheter for Meniere's disease: a retrospective study. ( Seidman, M, 2002) |
| "To determine the incidence, extent, and time course of hearing loss following instillation of intratympanic gentamicin using a predetermined fixed protocol for incapacitating unilateral Meniere's disease and to determine whether such loss is associated with any identifiable risk factors." | 3.71 | Hearing loss following intratympanic instillation of gentamicin for the treatment of unilateral Meniere's disease. ( Al-Abidi, A; Chen, JM; Kaplan, DM; Nedzelski, JM; Shipp, DB, 2002) |
| "Intratympanic injections of a prepared gentamicin concentration of approximately 30 mg/ml were given weekly until the patient reported cessation of vertigo attacks." | 3.70 | Intratympanic gentamicin injection for the treatment of Meniere's disease. ( Poe, DS; Youssef, TF, 1998) |
| "The subjective visual horizontal (SVH) was measured by means of a small, rotatable, luminous line in darkness in the upright head and body position and at 10, 20 and 30 degrees of tilt to the right and left before, and repeatedly during a follow-up period of 1 year after intratympanic gentamicin instillations in 12 patients with recurrent vertigo attacks." | 3.70 | Subjective visual horizontal during follow-up after unilateral vestibular deafferentation with gentamicin. ( Bergenius, J; Brantberg, K; Tribukait, A, 1998) |
| "Vertigo frequency, hearing status, personal disability ratings, tinnitus level, and caloric responses before and after gentamicin therapy were measured." | 3.70 | Intratympanic gentamicin titration therapy for intractable Meniere's disease. ( Atlas, JT; Parnes, LS, 1999) |
| "Intratympanic gentamicin is used to control dizziness of Ménière's disease, with a low rate of morbidity and a high success rate." | 3.70 | Low-dose intratympanic gentamicin treatment for dizziness in Ménière's disease. ( Longridge, NS; Mallinson, AI, 2000) |
| "The vestibulotoxic effect of gentamicin is well documented; however, there is no general agreement on the gentamicin dose needed to control vertigo attacks without affecting the hearing." | 3.70 | Round window gentamicin mu-catheter--a new therapeutic tool in Ménière's disease. ( Charabi, S; Thomsen, J; Tos, M, 2000) |
| "We have examined the effect of intratympanic gentamicin on hearing and tinnitus in 69 patients with intractable Menière's disease." | 3.69 | Effect of intratympanically administered gentamicin on hearing and tinnitus in Menière's disease. ( Aalto, H; Ishizaki, H; Kaasinen, S; Pyykkö, I, 1995) |
| "Adhering to the American Academy of Otolaryngology--Head and Neck Surgery 1985 criteria for reporting treatment results in Meniere's disease, the hearing status, control of vertigo, and disability scores using intratympanic gentamicin therapy were reported and compared with historical controls." | 3.69 | Intratympanic gentamicin therapy for Ménière's disease. ( Hirsch, BE; Kamerer, DB, 1997) |
| "To define better the benefits and risks of intratympanic gentamicin injection treatment of intractable vertigo or drop attacks due to Ménière's disease, we reviewed the charts of 18 patients whom we have now observed for > 1 year after having completed this mode of therapy." | 3.69 | Intratympanic gentamicin in Ménière's disease: results of therapy. ( Halmagyi, GM; Murofushi, T; Yavor, RA, 1997) |
| "Gentamicin given as local therapy for severe Menière's disease is of considerable value in the control of vertigo." | 3.69 | When and how to use gentamicin in the treatment of Menière's disease. ( Bergenius, J; Möller, C; Odkvist, LM, 1997) |
| "Intratympanic gentamicin therapy for vertigo in Meniere's disease was shown to be an effective treatment choice, as shown by our results." | 3.69 | Treatment of intractable Menière's disease with intratympanic gentamicin: review of the University of Ottawa experience. ( Corsten, M; Marsan, J; Robichaud, J; Schramm, D, 1997) |
| "To control attacks of vertigo while preserving both hearing and labyrinthine function, low doses of gentamicin were instilled intratympanically in nine patients with intractable unilateral Meniere's disease." | 3.69 | Low-dose intratympanic gentamicin treatment of Menière's disease. ( Inoue, H; Nogami, K; Uchi, Y; Uemura, T, 1994) |
| "Five patients with Menière's disease and disabling vertigo were treated with two intratympanic instillations of gentamicin given at an interval of about 12 h." | 3.68 | Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy. ( Magnusson, M; Padoan, S, 1991) |
| "For the medically refractory Meniere's disease patient, treatment options include intratympanic steroid injection, endolymphatic sac decompression, medical or surgical labyrinthectomy, and vestibular nerve section." | 3.01 | Recent surgical advances and continued controversies in medically refractory Meniere's disease. ( Hong, RS; Lucas, JC, 2023) |
| "Diagnosis criteria of Meniere's disease are classified into Meniere's disease with typical cochlear and vestibular symptoms, and atypical Meniere's disease with either cochlear symptoms or vestibular symptoms." | 2.72 | Diagnostic and therapeutic strategies for Meniere's disease of the Japan Society for Equilibrium Research. ( Iwasaki, S; Kitahara, T; Murofushi, T; Origasa, H; Seo, T; Shojaku, H; Suzuki, M; Takeda, N; Watanabe, Y, 2021) |
| "Seventy-one patients with unilateral Meniere's disease according to 1995 American Academy of Otolaryngology-Head and Neck Surgery 1995 guidelines who had been unresponsive to medical therapy for at least 1 year were studied." | 2.71 | Intratympanic gentamicin for intractable Meniere's disease. ( García-Tapia, R; Martín, E; Perez, N, 2003) |
| "Patients with Meniere's disease that remains refractory to conservative treatment have traditionally been subjected to ablative surgery." | 2.71 | Intratympanic gentamicin for unilateral Meniere's disease: results of therapy. ( Bottrill, I; Mitchell, AL; Wills, AD, 2003) |
| "To achieve both hearing preservation and vertigo control, the best treatment option among the pharmacologic interventions compared may be IT steroid plus high-dose betahistine, considering that IT gentamicin may have good performance to control vertigo but may be detrimental to hearing preservation with high cumulative dosage and short interval between injections." | 2.66 | Pharmacologic and surgical therapies for patients with Meniere's disease: A systematic review and network meta-analysis. ( Ahmadzai, N; Bonaparte, J; Cheng, W; Esmaeilisaraji, L; Fitzpatrick, E; Hutton, B; Kilty, S; Lin, V; Schramm, D; Skidmore, B; Wolfe, D, 2020) |
| "This article reviews 3 aspects of Meniere's disease (MD), which have been recently revisited: namely, the pathologic mechanism causing the attacks of vertigo, the clinical diagnosis, and the medical and surgical treatments." | 2.61 | Meniere's Disease. ( Gibson, WPR, 2019) |
| "Meniere's disease is an inner ear disease, characterized by recurrent rotatory vertigo, sensorineural hearing loss and tinnitus." | 2.58 | Evidence of surgical treatments for intractable Meniere's disease. ( Kitahara, T, 2018) |
| " Stabilizing matrices placed on the round window membrane for sustained passive delivery of compounds offer more controlled dosing profiles than transtympanic injections." | 2.44 | State-of-the-art mechanisms of intracochlear drug delivery. ( Borkholder, DA, 2008) |
| "To establish safe dosing protocols for the treatment of patients with Meniere's disease with intratympanic gentamicin." | 2.44 | Dependence of hearing changes on the dose of intratympanically applied gentamicin: a meta-analysis using mathematical simulations of clinical drug delivery protocols. ( Gill, RM; Plontke, SK; Salt, AN, 2008) |
| "Clinically, Meniere's syndrome includes the following features: recurrent, spontaneous episodic vertigo; hearing loss; aural fullness; and tinnitus." | 2.41 | Transtympanic gentamicin perfusion for the treatment of Meniere's disease. ( Schwaber, MK, 2002) |
| "Vertigo control rates for Meniere's disease have been excellent--rivaling other prominent surgical treatments--allowing intratympanic therapy to become the most prominent first-line treatment for Meniere's disease." | 2.41 | Chemical perfusion of the inner ear. ( Jackson, LE; Silverstein, H, 2002) |
| "Medical management of Meniere's disease is successful in approximately 70% of patients." | 2.40 | Role of chemical labyrinthectomy in the treatment of Meniere's disease. ( Hirsch, BE; Kamerer, DB, 1997) |
| "At two years post-treatment, the vertigo cure rate was 91." | 2.40 | [Chemical labyrinthectomy: results and applications]. ( Biboulet, R; Makeieff, M; Marlier, F; Mondain, M; Mouchet, F; Uziel, A, 1998) |
| "Vertigo control, Meniere's Disease Functional Level Scale (MDFLS), Dizziness Handicap Inventory (DHI), and pure tone audiometry pre and posttreatment." | 1.56 | On-Demand and Low Dose Intratympanic Gentamicin for Meniere's Disease: A Customized Approach. ( Alarid-Coronel, JM; Burgos-Paez, A; Castro-Bórquez, KM; Celis-Aguilar, E; Escobar-Aispuro, L; León-Leyva, IC; López-Favela, LM; Martínez-Román, L; Obeso-Pereda, A; Trejo-González, CF; Verdiales-Lugo, S, 2020) |
| "To investigate the effects of an intratympanic injection of dexamethasone combined with gentamicin on the expression level of serum P0 protein antibodies in patients with Meniere's disease (MD)." | 1.56 | Effects of an Intratympanic Injection of Dexamethasone Combined with Gentamicin on the Expression Level of Serum P0 Protein Antibodies in Patients with Meniere's Disease. ( Cao, W; Feng, T; Geng, Y; Wu, F; Xu, H, 2020) |
| "Gentamicin was administered every 2 weeks, up to three injections, until vertigo control was achieved." | 1.51 | Intratympanic Therapies in Ménière Disease: Evaluation of Outcomes and Early Vertigo Control. ( Brant, JA; Eliades, SJ; Henry, L; Naples, JG; Ruckenstein, MJ, 2019) |
| "A high success rates of treating vertigo attacks with low concentration ITG in refractory unilateral MD patients is herein reported, while a significant difference was not observed in the hearing threshold compared with the healthy contralateral ear." | 1.48 | Low Concentration Intra-Tympanic Gentamicin Treatment for Menière's Disease: A Long-Term Follow Up. ( Ephraim, E; Gavriel, H; Lasry, R; Marom, T; Nathan, S, 2018) |
| "Twenty five patients who had definite Meniere's disease and had either selective window application or weekly IT gentamicin were included into the study." | 1.46 | Selective Window Application of Gentamicin+ Dexamethasone in Meniere's Disease. ( Ardıç, FN; Aykal, K; Çabuk, B; Tümkaya, F, 2017) |
| "Gentamicin concentration was typically highest in samples originating from the vestibule and was lower in samples originating from scala tympani." | 1.43 | Perilymph pharmacokinetics of locally-applied gentamicin in the guinea pig. ( Gill, RM; Hartsock, JJ; King, E; Kraus, FB; Plontke, SK; Salt, AN, 2016) |
| "Gentamicin was detected in every cochlear cell type, but with spatiotemporal variability." | 1.42 | Cell-specific accumulation patterns of gentamicin in the guinea pig cochlea. ( Heinrich, UR; Helling, K; Schmidtmann, I; Strieth, S, 2015) |
| "Vertigo attacks in most cases of Meniere's disease (MD) are successfully treated with lifestyle changes and medication." | 1.40 | Intratympanic gentamicin as a treatment for drop attacks in patients with Meniere's disease. ( Bahmad, F; Rauch, SD; Viana, LM, 2014) |
| "To assess the utility of imaging in planning intratympanic (IT) gentamicin (Gent) treatment in Ménière's disease (MD), we compared the dosage and outcomes of ITGent with the severity and extent of endolymphatic hydrops (EH), as evaluated by three-dimensional fluid-attenuated inversion recovery (3D-FLAIR) sequence in a 3-T magnetic resonance imaging (MRI) unit, after IT gadolinium administration." | 1.38 | Variability in the perilymphatic diffusion of gadolinium does not predict the outcome of intratympanic gentamicin in patients with Ménière's disease. ( Barbieri, F; Beltramello, A; Fiorino, F; Pizzini, FB, 2012) |
| "The skew deviation and diplopia resolved spontaneously and completely within 6 to 8 weeks without therapy." | 1.37 | Skew deviation after intratympanic gentamicin therapy. ( Fouladvand, M; Lalwani, AK; Ng, D, 2011) |
| "Gentamicin was applied to the ear of mice either through ITGI or in the hydrogel system." | 1.36 | A controlled and sustained local gentamicin delivery system for inner ear applications. ( Bigelow, D; Heldrich, J; Li, A; Li, D; Miyamoto, S; O'Malley, B; Ruckenstein, M; Uboh, CE; Wang, H; Xu, L; Yamashita, T; You, Y, 2010) |
| "Twelve patients with unilateral Meniere's disease were evaluated with pure tone audiometry (PTA), bithermal caloric tests, and VEMP tests." | 1.35 | Reliability of the vestibular evoked myogenic potential test in assessing intratympanic gentamicin therapy in Meniere's disease. ( Akkuzu, G; Ozgirgin, N; Ozluoglu, LN; Tarhan, E, 2008) |
| "Twenty-six patients with severe Meniere's disease treated with intratympanically applied gentamicin of the affected ear were examined." | 1.35 | Oculomotor findings mimicking a cerebellar disorder and postural control in severe Meniere's disease. ( Heikki, A; Ilmari, P; Isotalo, E, 2009) |
| "Nineteen patients with Meniere's disease were treated with intratympanic gentamicin injection." | 1.34 | [The effects of small dose of intratympanic gentamicin injection on intractable Meniere's disease]. ( Chi, F; Dai, C; Liu, J; Wang, Z; Zhang, G; Zhang, R, 2007) |
| "However, the risk of sensorineural hearing loss was much lower for a single injection than for multiple injections." | 1.34 | Effects of a single intratympanic gentamicin injection on Meniere's disease. ( Cho, YS; Chung, KW; Chung, WH; Hong, SH; Kim, JH, 2007) |
| "The intratympanic application of a low dosage of gentamicin is increasingly favored as treatment for Ménière's disease." | 1.34 | Treatment of Ménière's disease by low-dosage intratympanic gentamicin application: effect on otolith function. ( Clarke, AH; Helling, K; Schönfeld, U, 2007) |
| "Surgical management of Meniere's disease is a safe and viable option for patients with medically refractory disease." | 1.33 | Surgical management of Meniere's disease in the era of gentamicin. ( Gardner, EK; Jackson, CG; Kaylie, DM, 2005) |
| "Treatment of drop attacks is still a matter of discussion; most cases have a benign course with spontaneous remission and no treatment is necessary." | 1.33 | Drop attacks and vertical vertigo after transtympanic gentamicin: diagnosis and management. ( Bignami, M; Bruschini, L; Casani, AP; Dallan, I; Nacci, A, 2005) |
| "Relief of vertigo was assessed by chart review and telephone interviews." | 1.33 | Long-term follow-up after gentamicin application via the Silverstein MicroWick in the treatment of Ménière's disease. ( Digges, EN; Hill, SL; Silverstein, H, 2006) |
| "If there was a recurrence of the episodes of vertigo, an additional course of injections was performed." | 1.32 | Hearing loss after intratympanic gentamicin therapy for unilateral Ménière's Disease. ( Martin, E; Perez, N, 2003) |
| "Vertigo was controlled in 95 per cent, whilst preserving hearing in 77 per cent." | 1.32 | Long-term results of gentamicin inner ear perfusion in Ménière's disease. ( Cook, JA; Suryanarayanan, R, 2004) |
| " The authors discuss the results obtained with a low dosage transtympanic administration of gentamicin in a series of 29 patients followed up for two years." | 1.31 | [Transtympanic gentamicin in Ménière's disease: evaluation of the quality of life]. ( Chiappetta, A; Comacchio, F; Fernandez, S; Martinez-Monche, G; Staffieri, A, 2001) |
| "Gentamicin was delivered either transtympanically (preoperative) or through a facial recess approach (intraoperative)." | 1.31 | Round window gentamicin absorption: an in vivo human model. ( Becvarovski, Z; Bojrab, DI; Kartush, JM; LaRouere, MJ; Michaelides, EM; Zappia, JJ, 2002) |
| "Understanding the pathogenesis of Meniere's disease can result from studying its natural history; however, a marvelous opportunity for this understanding exists in surgical revisions of endolymphatic sac enhancement." | 1.31 | Revision of endolymphatic sac surgery for recurrent Meniere's disease. ( Paparella, MM, 2002) |
| "The ablation treatment of Meniere's disease by intratympanic streptomycin applications was first reported by Schuknecht in 1957." | 1.31 | [Use of intratympanic gentamycin for the treatment of Meniere's disease]. ( Held-Ziółkowska, M; Kowalska, M; Krzeska-Malinowska, I; Niemczyk, K; Pierchała, K, 2001) |
| "25 mg gentamycin on the 3rd and 7th day after insertion of the new microcatheter at the niche of the round window membrane, while a second group of 7 patients was treated by a gentamycin dosage of 1 microliter/h continuously applied by a minipump over a period of 10 days." | 1.31 | [Round window microcatheter administered microdose of gentamycin: an alternative in the treatment of tinnitus in patients with Menière's disease]. ( Arenberg, IK; Hoffer, ME; Marks, S, 2000) |
| "Gentamicin (26." | 1.31 | Intratympanic gentamicin for the treatment of unilateral Meniere's disease. ( Chen, JM; Kaplan, DM; Nedzelski, JM; Shipp, DB, 2000) |
| "Gentamicin was applied by a high-precision insulin pump with a flow rate of 40 mg per day directly in front of the round window." | 1.31 | Continuous intratympanic infusion of gentamicin via a microcatheter in Menière's disease. ( Michel, O; Neugebauer, P; Schoendorf, J, 2001) |
| "Patients with confirmed Meniere's disease underwent placement of the Round Window Microcatheter, which was filled with 10 mg/mL gentamicin, after placement into the round window niche was confirmed." | 1.31 | Use of the round window microcatheter in the treatment of Meniere's disease. ( Allen, K; Balaban, C; Gottshall, K; Hoffer, ME; Kopke, RD; Weisskopf, P; Wester, D, 2001) |
| "Of these, 68 patients had Meniere's disease; 4 patients had recurrent vertigo after endolymphatic sac surgery and were followed for at least 1 year." | 1.31 | Intratympanic gentamicin therapy for persistent vertigo after endolymphatic sac surgery. ( Leonetti, JP; Marzo, SJ, 2002) |
| "In 2 patients with severe Meniere's disease (MD), there was histologic evidence of occlusion of the vein of the vestibular aqueduct (VVA)." | 1.31 | Vascular occlusion in the endolymphatic sac in Meniere's disease. ( Friberg, U; Rask-Andersen, H, 2002) |
| "Tinnitus was attenuated in 3 patients, while 1 patient suffered from posttherapeutic onset of tinnitus." | 1.31 | [Follow-up assessment of intratympanic gentamicin therapy and Saccotomia in Menière's Disease]. ( Issing, WJ; Jäger, L; Tauber, S, 2002) |
| " Herein we report our results of intratympanic gentamicin therapy in 21 patients using two different dosing protocols, twice weekly and twice daily (b." | 1.30 | Intratympanic gentamicin for treatment of intractable Meniere's disease: a preliminary report. ( Oas, JG; Rauch, SD, 1997) |
| "Clinically significant sensorineural hearing loss occurred in 5 (20%) of 25 ears." | 1.30 | Intratympanic gentamicin treatment for Meniere's disease. ( Antonelli, PJ; McFeely, WJ; Rodriguez, FJ; Singleton, GT, 1998) |
| "Two years after the treatment, rotatory vertigo was abolished in 81% of subjects, Tumarkin attacks were cured in 60%, and work capacity was severely reduced in 10% and moderately reduced in 17% of subjects." | 1.30 | Intratympanic gentamicin in Meniere's disease. ( Aalto, H; Ishizaki, H; Kaasinen, S; Pyykkö, I, 1998) |
| "Ten chinchillas underwent left middle ear instillation of one of three agents using variable dosing schedules: gentamicin (n = 6), streptomycin (n = 2), and saline (n = 2) as control." | 1.30 | Middle ear instillation of gentamicin and streptomycin in chinchillas: morphologic appraisal of selective ototoxicity. ( Chen, JM; Harrison, RV; Hirakawa, H; Kakigi, A; Mount, RJ, 1999) |
| "Twelve patients with unilateral Meniere's disease were treated and prospectively studied." | 1.29 | Irritative spontaneous nystagmus following intratympanic gentamicin for Menière's disease. ( Parnes, LS; Riddell, D, 1993) |
| " We propose individual dosage depending on hearing threshold and intensity of symptoms." | 1.29 | [27 years experiences with transtympanic aminoglycoside treatment of Menière's disease]. ( Lange, G, 1995) |
| "A major risk of the treatment is sensorineural hearing loss." | 1.29 | Intratympanic gentamicin therapy for Menière's disease: preliminary comparison of two regimens. ( Parnes, LS; Toth, AA, 1995) |
| "Seven patients with intractable Meniere's disease underwent elective transtympanic gentamycin labyrinthectomy." | 1.29 | Ocular torsion monitoring in chemical labyrinthectomy. ( Garber, LZ; Ireland, DJ; Robertson, DD, 1996) |
| "Streptomycin was injected subcutaneously into guinea pigs (n = 12) with unilateral endolymphatic hydrops." | 1.28 | Effects of systemic and lateral semicircular canal administration of aminoglycosides on normal and hydropic inner ears. ( Kimura, RS; Lee, KS; Nye, CL; Trehey, JA, 1991) |
| "Tinnitus is a very serious problem in otolaryngology." | 1.28 | [Treatment of tinnitus with gentamicin]. ( Kucera, P; Novotný, M, 1990) |
| " Dosage was titrated up to the initial symptoms of vestibular or cochlear intoxication." | 1.28 | [Long-term results of gentamycin therapy of Menière's disease]. ( Blessing, RE; Schlenter, WW, 1989) |
| "Fifteen patients with disabling Meniere's disease were treated with local intratympanic administration of gentamicin once daily." | 1.27 | Vestibular and audiologic functions in gentamicin-treated Menière's disease. ( Hydén, D; Larsby, B; Möller, C; Odkvist, LM; Thell, J, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 22 (6.57) | 18.7374 |
| 1990's | 58 (17.31) | 18.2507 |
| 2000's | 140 (41.79) | 29.6817 |
| 2010's | 83 (24.78) | 24.3611 |
| 2020's | 32 (9.55) | 2.80 |
| Authors | Studies |
|---|---|
| van Esch, BF | 1 |
| van der Zaag-Loonen, H | 1 |
| Bruintjes, T | 1 |
| Kuijpers, T | 1 |
| van Benthem, PPG | 1 |
| de Amesti, F | 1 |
| Santander, MJ | 1 |
| Winter, M | 1 |
| Hilton, A | 1 |
| McClelland, A | 1 |
| McCallum, R | 1 |
| Kontorinis, G | 1 |
| Li, S | 2 |
| Pyykkö, I | 8 |
| Zhang, Q | 2 |
| Yang, J | 3 |
| Duan, M | 4 |
| Ilmari, P | 2 |
| Spiegel, JL | 1 |
| Stoycheva, I | 1 |
| Weiss, BG | 1 |
| Bertlich, M | 1 |
| Rader, T | 1 |
| Canis, M | 1 |
| Ihler, F | 1 |
| Webster, KE | 1 |
| Galbraith, K | 1 |
| Lee, A | 1 |
| Harrington-Benton, NA | 1 |
| Judd, O | 1 |
| Kaski, D | 1 |
| Maarsingh, OR | 1 |
| MacKeith, S | 1 |
| Ray, J | 1 |
| Van Vugt, VA | 1 |
| Burton, MJ | 1 |
| Phillips, J | 1 |
| Mikulec, AA | 1 |
| Robinson, JM | 1 |
| Skarinsky, D | 1 |
| Anderson, JJ | 1 |
| Lucas, JC | 1 |
| Hong, RS | 1 |
| Yaz, F | 2 |
| Ziylan, F | 2 |
| Smeeing, DPJ | 2 |
| Thomeer, HGXM | 2 |
| Gibson, AW | 1 |
| Moon, IJ | 1 |
| Golub, JS | 1 |
| Rubinstein, JT | 1 |
| Lee, JY | 1 |
| Kim, MB | 1 |
| Scarpa, A | 3 |
| Ralli, M | 3 |
| De Luca, P | 3 |
| Savignano, L | 1 |
| Gioacchini, FM | 2 |
| Cassandro, E | 3 |
| Cassandro, C | 3 |
| Sacks, C | 1 |
| Saadi, R | 1 |
| Isildak, H | 1 |
| Celis-Aguilar, E | 1 |
| Castro-Bórquez, KM | 1 |
| Obeso-Pereda, A | 1 |
| Escobar-Aispuro, L | 1 |
| Burgos-Paez, A | 1 |
| Alarid-Coronel, JM | 1 |
| Verdiales-Lugo, S | 1 |
| León-Leyva, IC | 1 |
| Trejo-González, CF | 1 |
| López-Favela, LM | 1 |
| Martínez-Román, L | 1 |
| Quaranta, N | 4 |
| Picciotti, P | 2 |
| Molnár, A | 2 |
| Maihoub, S | 2 |
| Gáborján, A | 2 |
| Tamás, L | 2 |
| Szirmai, Á | 2 |
| Basura, GJ | 2 |
| Adams, ME | 1 |
| Monfared, A | 1 |
| Schwartz, SR | 1 |
| Antonelli, PJ | 2 |
| Burkard, R | 1 |
| Bush, ML | 1 |
| Bykowski, J | 1 |
| Colandrea, M | 1 |
| Derebery, J | 1 |
| Kelly, EA | 1 |
| Kerber, KA | 1 |
| Koopman, CF | 1 |
| Kuch, AA | 1 |
| Marcolini, E | 1 |
| McKinnon, BJ | 1 |
| Ruckenstein, MJ | 2 |
| Valenzuela, CV | 1 |
| Vosooney, A | 1 |
| Walsh, SA | 1 |
| Nnacheta, LC | 1 |
| Dhepyasuwan, N | 1 |
| Buchanan, EM | 1 |
| Viola, P | 1 |
| Greco, A | 1 |
| de Vincentiis, M | 1 |
| Espinosa-Sanchez, JM | 1 |
| Lopez-Escamez, JA | 1 |
| Liu, Y | 1 |
| Jiang, M | 1 |
| Zhang, Z | 1 |
| Zhao, C | 1 |
| Bergmark, RW | 1 |
| Semco, RS | 1 |
| Abdul-Aziz, D | 1 |
| Rauch, SD | 4 |
| Ahmadzai, N | 1 |
| Cheng, W | 1 |
| Kilty, S | 1 |
| Esmaeilisaraji, L | 1 |
| Wolfe, D | 1 |
| Bonaparte, J | 1 |
| Schramm, D | 2 |
| Fitzpatrick, E | 1 |
| Lin, V | 1 |
| Skidmore, B | 1 |
| Hutton, B | 1 |
| Iwasaki, S | 2 |
| Shojaku, H | 1 |
| Murofushi, T | 3 |
| Seo, T | 1 |
| Kitahara, T | 4 |
| Origasa, H | 1 |
| Watanabe, Y | 1 |
| Suzuki, M | 1 |
| Takeda, N | 1 |
| Cavaliere, M | 1 |
| Gill, C | 1 |
| Muzaffar, J | 1 |
| Kumar, R | 1 |
| Irving, R | 1 |
| Geng, Y | 1 |
| Cao, W | 1 |
| Xu, H | 2 |
| Wu, F | 1 |
| Feng, T | 1 |
| Hao, W | 1 |
| Yu, H | 1 |
| Li, H | 1 |
| Wu, Y | 1 |
| Zhou, Y | 1 |
| Yu, J | 1 |
| Song, Z | 1 |
| Dai, C | 6 |
| Wang, J | 1 |
| Volkenstein, S | 1 |
| Dazert, S | 1 |
| Liu, YF | 1 |
| Renk, E | 1 |
| Xu, HX | 1 |
| Pullen, RL | 1 |
| Ardıç, FN | 1 |
| Tümkaya, F | 1 |
| Aykal, K | 1 |
| Çabuk, B | 1 |
| Shamas, IU | 1 |
| Marques, PS | 1 |
| Dias, CC | 1 |
| Perez-Fernandez, N | 7 |
| Spratley, J | 2 |
| Wu, Q | 3 |
| Zhang, Y | 4 |
| Kong, Y | 1 |
| Pan, L | 1 |
| Wang, XY | 1 |
| Zhuang, HY | 1 |
| Xiong, GX | 1 |
| Wu, X | 1 |
| Chen, XH | 1 |
| Büki, B | 4 |
| Jünger, H | 4 |
| Lundberg, YW | 1 |
| Nathan, S | 1 |
| Lasry, R | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effectiveness of Transtympanic Steroids in Unilateral Ménière's Disease: a Randomised Controlled Double-Blind Trial[NCT00802529] | Phase 2/Phase 3 | 60 participants (Actual) | Interventional | 2009-04-30 | Completed | ||
| Gentamicin Treatment Prior to Vestibular Schwannoma Surgery in Patients With Definite Remaining Vestibular Function[NCT02379754] | Phase 4 | 0 participants (Actual) | Interventional | 2015-01-31 | Withdrawn | ||
| Gentamicin Treatment Prior to Vestibular Schwannoma Surgery in Patients With no Measurable Remaining Vestibular Function[NCT02415257] | Phase 4 | 0 participants (Actual) | Interventional | 2015-04-30 | Withdrawn | ||
| Comparing Topical Tetracaine Drops to Topical Focal Phenol for Local Anesthesia During Intratympanic Steroid Injection[NCT04794842] | Early Phase 1 | 80 participants (Actual) | Interventional | 2021-08-01 | Active, not recruiting | ||
| Reduction of Plasma Vasopressin Level in Patients With Meniere's Disease[NCT01099046] | 200 participants (Anticipated) | Interventional | 2009-01-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Hearing was measured as ipsilesional pure-tone threshold at Baseline, 1month, 2months, 6months, 12month, 18months and 24 months follow-up. Hearing level was taken as the average threshold across 0.5, 1, 2 and 3KHz. (NCT00802529)
Timeframe: Baseline, 1,2,6,12,18 and 24months after initial treatment
| Intervention | dB (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Baseline | 1month | 2months | 6months | 12months | 18months | 24months | |
| Gentamicin | 51.5 | 52.18 | 48.99 | 45.48 | 47.34 | 44.82 | 49.1 |
| Steroid (Methylprednisolone) | 53.25 | 49.29 | 49.83 | 46.67 | 47.02 | 48.44 | 46.9 |
"Speech discrimination was measured at Baseline, 1month, 2months, 6months, 12month and 24 months follow-up.~Speech discrimination was assessed by means of ipsilesional suprathreshold word recognition (%). Arthur Boothroyd's isophonemic word lists (AB wordlists, Guymark, Southampton) comprising sets of 10 words were played to the ipsilesional ear at the low-frequency pure-tone threshold of 0·5, 1 and 2 kHz +30dB with masking sound in the contralesional ear if necessary. The formula for masking level was: low-frequency pure-tone threshold in ipsilesional ear - bone conduction mean threshold (0·5, 1 and 2KHz) in contralesional ear - 40dB. Speech loudness and masking were rounded to the nearest 5dB. Step increments and decrements of 10dB for speech loudness and masking were used to attain the maximum speech discrimination score." (NCT00802529)
Timeframe: Baseline, 1,2,6,12 and 24months after initial treatment
| Intervention | Percentage correct (Mean) | |||||
|---|---|---|---|---|---|---|
| Baseline | 1month | 2months | 6months | 12months | 24months | |
| Gentamicin | 72.10 | 69.43 | 74.31 | 76.35 | 71.58 | 64.99 |
| Steroid (Methylprednisolone) | 64.97 | 71.78 | 76.10 | 75.63 | 73.43 | 76.32 |
The number of vertigo attacks between 18-24months follow-up were taken retrospectively during a face-to-face appointment at 24 months follow-up and compared to 6 month pre-enrollment baseline (as per Committee on Hearing and Equilibrium guidelines). (NCT00802529)
Timeframe: 6month pre-enrollment baseline, 18-24 months after initial treatment
| Intervention | Vertigo Attacks (Mean) | |
|---|---|---|
| Baseline | 18-24months | |
| Gentamicin | 19.93 | 2.5 |
| Steroid (Methylprednisolone) | 16.4 | 1.6 |
50 reviews available for gentamicin and Meniere Disease
| Article | Year |
|---|---|
Interventions for Menière's disease: an umbrella systematic review.
Topics: Gentamicins; Humans; Meniere Disease; Steroids | 2022 |
Intratympanic gentamicin compared with placebo for Ménière's disease.
Topics: Gentamicins; Humans; Meniere Disease; Systematic Reviews as Topic; Tinnitus; Vertigo | 2022 |
Consensus on intratympanic drug delivery for Menière's disease.
Topics: Anti-Bacterial Agents; Consensus; Gentamicins; Humans; Injection, Intratympanic; Meniere Disease; Tr | 2022 |
Intratympanic gentamicin for Ménière's disease.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Gentamicins; Humans; Meniere Disease; Tinnitus; Verti | 2023 |
Recent surgical advances and continued controversies in medically refractory Meniere's disease.
Topics: Deafness; Ear, Inner; Gentamicins; Hearing Loss; Humans; Meniere Disease; Vertigo | 2023 |
Intratympanic Treatment in Menière's Disease, Efficacy of Aminoglycosides Versus Corticosteroids in Comparison Studies: A Systematic Review.
Topics: Adrenal Cortex Hormones; Aminoglycosides; Anti-Inflammatory Agents; Dexamethasone; Female; Gentamici | 2020 |
The pharmacological management of vertigo in Meniere disease.
Topics: Adrenal Cortex Hormones; Betahistine; Clinical Trials as Topic; Diuretics; Female; Gentamicins; Huma | 2020 |
Current status on researches of Meniere's disease: a review.
Topics: Adrenal Cortex Hormones; Betahistine; Endolymphatic Hydrops; Endolymphatic Sac; Gentamicins; Humans; | 2020 |
What is the efficacy of gentamicin on the incidence of vertigo attacks and hearing in patients with Meniere's disease compared with steroids? A meta-analysis.
Topics: Anti-Bacterial Agents; Gentamicins; Hearing; Humans; Incidence; Meniere Disease; Steroids; Treatment | 2021 |
Pharmacologic and surgical therapies for patients with Meniere's disease: A systematic review and network meta-analysis.
Topics: Anti-Bacterial Agents; Betahistine; Gentamicins; Hearing; Humans; Meniere Disease; Steroids; Treatme | 2020 |
Diagnostic and therapeutic strategies for Meniere's disease of the Japan Society for Equilibrium Research.
Topics: Anti-Bacterial Agents; Audiometry; Endolymphatic Hydrops; Endolymphatic Sac; Gentamicins; Healthy Li | 2021 |
Effects of intratympanic gentamicin and intratympanic glucocorticoids in Ménière's disease: a network meta-analysis.
Topics: Anti-Bacterial Agents; Audiometry, Pure-Tone; Gentamicins; Glucocorticoids; Humans; Meniere Disease; | 2022 |
[Recent surgical options for vestibular vertigo].
Topics: Cochlear Implantation; Decompression, Surgical; Denervation; Evidence-Based Medicine; Gentamicins; H | 2017 |
Evidence of surgical treatments for intractable Meniere's disease.
Topics: Ablation Techniques; Denervation; Endolymphatic Sac; Endolymphatic Shunt; Evidence-Based Medicine; G | 2018 |
Instrumental head impulse test changes after intratympanic gentamicin for unilateral definite Ménière's disease: A systematic review and meta-analysis.
Topics: Gentamicins; Head Impulse Test; Humans; Injection, Intratympanic; Meniere Disease; Protein Synthesis | 2018 |
European Position Statement on Diagnosis, and Treatment of Meniere's Disease.
Topics: Anti-Bacterial Agents; Betahistine; Consensus; Conservative Treatment; Denervation; Diuretics; Endol | 2018 |
The Clinical Outcomes After Intratympanic Gentamicin Injection to Treat Menière's Disease: A Meta-analysis.
Topics: Gentamicins; Humans; Injection, Intratympanic; Meniere Disease; Protein Synthesis Inhibitors; Treatm | 2019 |
Meniere's Disease.
Topics: Anti-Bacterial Agents; Diagnosis, Differential; Gentamicins; Humans; Meniere Disease; Otologic Surgi | 2019 |
Different medications for the treatment of Ménière's disease by intratympanic injection: A systematic review and network meta-analysis.
Topics: Dexamethasone; Ganciclovir; Gentamicins; Humans; Injection, Intratympanic; Latanoprost; Meniere Dise | 2019 |
Is gentamycin delivery via sustained-release vehicles a safe and effective treatment for refractory Meniere's disease? A critical analysis of published interventional studies.
Topics: Anti-Bacterial Agents; Catheters; Delayed-Action Preparations; Gentamicins; Humans; Meniere Disease; | 2017 |
State-of-the-art mechanisms of intracochlear drug delivery.
Topics: Adrenal Cortex Hormones; Animals; Cochlea; Dose-Response Relationship, Drug; Drug Administration Sch | 2008 |
Dependence of hearing changes on the dose of intratympanically applied gentamicin: a meta-analysis using mathematical simulations of clinical drug delivery protocols.
Topics: Cochlea; Computer Simulation; Ear, Inner; Ear, Middle; Gentamicins; Hearing; Humans; Injections; Men | 2008 |
Intratympanic gentamicin for Ménière's disease or syndrome.
Topics: Anti-Bacterial Agents; Ear, Middle; Gentamicins; Humans; Meniere Disease; Randomized Controlled Tria | 2011 |
Meniere's disease: an evidence based approach to assessment and management.
Topics: Antiemetics; Audiometry; Betahistine; Biomarkers; Catheter Ablation; Central Nervous System Agents; | 2012 |
Outcomes of intratympanic gentamicin injection to treat Ménière's disease.
Topics: Anti-Bacterial Agents; Gentamicins; Humans; Meniere Disease; Treatment Outcome; Tympanic Membrane | 2012 |
Transtympanic gentamicin perfusion for the treatment of Meniere's disease.
Topics: Administration, Topical; Anti-Bacterial Agents; Gentamicins; Humans; Meniere Disease; Otologic Surgi | 2002 |
Chemical perfusion of the inner ear.
Topics: Adrenal Cortex Hormones; Anesthesia, General; Anti-Bacterial Agents; Catheterization; Contraindicati | 2002 |
Chemical and physical labyrinthectomy for Meniere's disease.
Topics: Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Ear, Inner; Ear, Middle; Electrony | 2002 |
Treatment of Ménière's disease by intratympanic gentamicin application.
Topics: Absorption; Administration, Topical; Anti-Bacterial Agents; Gentamicins; Humans; Meniere Disease; Tr | 2003 |
Systematic review of intratympanic gentamicin in Meniere's disease.
Topics: Administration, Topical; Anti-Bacterial Agents; Ear, Inner; Gentamicins; Hearing; Humans; Meniere Di | 2003 |
Ménière's disease.
Topics: Combined Modality Therapy; Diet, Sodium-Restricted; Diuretics; Ear, Middle; Electronystagmography; E | 2004 |
Intratympanic gentamicin therapy for Ménière's disease: a meta-analysis.
Topics: Anti-Bacterial Agents; Catheter Ablation; Gentamicins; Hearing Loss; Humans; Meniere Disease; Treatm | 2004 |
Transtympanic perfusion: indications and limitations.
Topics: Adult; Audiometry; Child; Child, Preschool; Dexamethasone; Ear, Middle; Female; Follow-Up Studies; G | 2004 |
Sustained-release devices in inner ear medical therapy.
Topics: Administration, Topical; Anti-Bacterial Agents; Delayed-Action Preparations; Drug Delivery Systems; | 2004 |
Intratympanic gentamicin for the treatment of Meniere's disease and other forms of peripheral vertigo.
Topics: Administration, Topical; Anti-Bacterial Agents; Gentamicins; Humans; Meniere Disease; Round Window, | 2004 |
Intratympanic gentamicin for Menière's disease: a meta-analysis.
Topics: Audiometry; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Fem | 2004 |
Surgical treatment of Meniere's disease.
Topics: Animals; Anti-Bacterial Agents; Gentamicins; Humans; Meniere Disease; Treatment Outcome | 2005 |
Meta-analysis of intratympanic gentamicin.
Topics: Anti-Bacterial Agents; Gentamicins; Humans; Meniere Disease; Tympanic Membrane; Vertigo | 2005 |
Menière's disease: myths and realities.
Topics: Anti-Bacterial Agents; Gentamicins; Humans; Meniere Disease; Mental Disorders; Patient Education as | 2005 |
An update on the surgical treatment of Ménière's diseases.
Topics: Anti-Bacterial Agents; Ear, Inner; Endolymphatic Sac; Gentamicins; Hearing Loss; Humans; Meniere Dis | 2006 |
Delivery of drugs to the inner ear.
Topics: Drug Delivery Systems; Ear, Inner; Gentamicins; Glucocorticoids; Hearing Loss, Sudden; Humans; Menie | 2006 |
Intratympanic gentamicin instillation as treatment of unilateral Menière's disease: update of an ongoing study.
Topics: Adult; Aged; Audiometry, Pure-Tone; Female; Gentamicins; Hearing; Humans; Male; Meniere Disease; Tym | 1993 |
Clinical forum: a review of intratympanic therapy.
Topics: Anti-Bacterial Agents; Gentamicins; Hearing Disorders; Humans; Meniere Disease; Streptomycin; Termin | 1997 |
Role of chemical labyrinthectomy in the treatment of Meniere's disease.
Topics: Ear, Inner; Gentamicins; Hearing Loss, Sensorineural; Humans; Meniere Disease | 1997 |
[Chemical labyrinthectomy: results and applications].
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ear, Inner; Female; Gentamicins; Humans; Male | 1998 |
Use of a new device, the MicroWick, to deliver medication to the inner ear.
Topics: Anti-Bacterial Agents; Autoimmune Diseases; Dexamethasone; Drug Delivery Systems; Ear Diseases; Ear, | 1999 |
Update on intratympanic gentamicin for Meniere's disease.
Topics: Gentamicins; Humans; Injections, Intralesional; Meniere Disease; Tympanic Membrane | 2000 |
[Meniere's disease: diagnosis and new treatment perspectives].
Topics: Diagnosis, Differential; Ear, Inner; Endolymphatic Shunt; Follow-Up Studies; Gentamicins; Humans; Me | 2000 |
[Menière's disease. Current status].
Topics: Aged; Anti-Bacterial Agents; Betahistine; Ear, Inner; Endolymphatic Sac; Endoscopy; Gentamicins; His | 2001 |
[Pathophysiology, clinical aspects and conservative therapy of Menière disease].
Topics: Animals; Combined Modality Therapy; Diagnosis, Differential; Endolymph; Endolymphatic Duct; Endolymp | 1985 |
29 trials available for gentamicin and Meniere Disease
| Article | Year |
|---|---|
Efficacy of Intratympanic OTO-104 for the Treatment of Ménière's Disease: The Outcome of Three Randomized, Double-Blind, Placebo-Controlled Studies.
Topics: Double-Blind Method; Gentamicins; Humans; Injection, Intratympanic; Injections; Meniere Disease; Tre | 2023 |
Author's reply to the Letter to the Editor "Therapeutic strategies in the treatment of Menière's disease: the Italian experience".
Topics: Anti-Bacterial Agents; Gentamicins; Humans; Italy; Meniere Disease; Treatment Outcome; Vertigo | 2020 |
Short Term Results of Intra Tympanic Gentamicin and Dexamethasone on Hearing and Tinnitus in Meniere's disease: A Case Control Study.
Topics: Audiometry, Pure-Tone; Case-Control Studies; Dexamethasone; Gentamicins; Glucocorticoids; Hearing; H | 2017 |
Topics: Double-Blind Method; Female; Gentamicins; Humans; Injections; Male; Meniere Disease; Methylprednisol | 2017 |
Intratympanic gentamicin treatment for Ménière's disease: a randomized, double-blind, placebo-controlled trial on dose efficacy - results of a prematurely ended study.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Dose-Response Relationship, Drug; Double- | 2014 |
The effect of intratympanic gentamicin for treatment of Ménière's disease on lower frequency hearing.
Topics: Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Female; Gentamicins; Hearing; Humans; Injection, | 2016 |
Intratympanic methylprednisolone versus gentamicin in patients with unilateral Ménière's disease: a randomised, double-blind, comparative effectiveness trial.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Double-Blind Method; Female; Gentamicins; Hearing L | 2016 |
Intratympanic gentamicin therapy for control of vertigo in unilateral Menire's disease: a prospective, double-blind, randomized, placebo-controlled trial.
Topics: Anti-Bacterial Agents; Double-Blind Method; Drug Administration Schedule; Ear, Middle; Female; Follo | 2008 |
Intratympanic gentamicin in Ménière's disease: our experience.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug Administration Schedule; Epidemiologic M | 2011 |
Intratympanic treatment of intractable unilateral Meniere disease: gentamicin or dexamethasone? A randomized controlled trial.
Topics: Adult; Aged; Chronic Disease; Dexamethasone; Dose-Response Relationship, Drug; Drug Administration S | 2012 |
Pain assessment of the intratympanic injections: a prospective comparative study.
Topics: Adolescent; Adult; Aged; Anesthetics, Local; Anti-Bacterial Agents; Anti-Inflammatory Agents; Female | 2012 |
Intratympanic gentamicin in Menière's disease: the impact on tinnitus.
Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Bacterial Agents; Female; Gentamicins; Humans | 2002 |
Intratympanic gentamicin injections for Meniere disease: vestibular hair cell impairment and regeneration.
Topics: Adult; Aged; Anti-Bacterial Agents; Caloric Tests; Evoked Potentials, Auditory; Female; Gentamicins; | 2002 |
Intratympanic gentamicin for intractable Meniere's disease.
Topics: Adult; Anti-Bacterial Agents; Audiometry, Pure-Tone; Auditory Threshold; Female; Follow-Up Studies; | 2003 |
Intratympanic gentamicin for unilateral Meniere's disease: results of therapy.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Female; Gentamicins; Humans; Injections; Male | 2003 |
Menière's disease and gentamicin: preliminary results using the minimum effective dose and integrated therapy.
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Endol | 2003 |
Selective vestibular ablation by intratympanic gentamicin in patients with unilateral active Ménière's disease: a prospective, double-blind, placebo-controlled, randomized clinical trial.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Auditory Threshold; Double-Blind Method; | 2004 |
Vestibular function at the end of intratympanic gentamicin treatment of patients with Ménière's disease.
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Audiometry; Caloric Tests; Electrooculo | 2005 |
Transtympanic gentamicin and fibrin tissue adhesive for treatment of unilateral Menière's disease: effects on vestibular function.
Topics: Adult; Aged; Aged, 80 and over; Drug Therapy, Combination; Ear, Middle; Female; Fibrin Tissue Adhesi | 2005 |
Recovery of subjective visual horizontal after unilateral vestibular deafferentation by intratympanic instillation of gentamicin.
Topics: Adult; Aged; Caloric Tests; Drug Administration Routes; Ear, Middle; Electronystagmography; Female; | 2006 |
[Intratympanic treatment in Meniere's disease: the effect of gentamicin and dexamethasone on vertigo control and hearing].
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Dexamethasone; Drug Therapy, Combination; Female; G | 2006 |
Intratympanic gentamicin for control of vertigo in Meniere's disease: vestibular signs that specify completion of therapy.
Topics: Adult; Aged; Caloric Tests; Clinical Protocols; Ear, Inner; Female; Gentamicins; Hearing Disorders; | 1999 |
Direct round window membrane application of gentamicin in the treatment of Meniere's disease.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry; Caloric Tests; Clinical Protocols | 1999 |
Effect of intratympanic gentamicin on hearing and tinnitus in Meniere's disease.
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Deafness; Decomp | 1999 |
Does intratympanic gentamicin treatment for Meniere's disease cause complete vestibular ablation?
Topics: Adult; Caloric Tests; Electronystagmography; Female; Gentamicins; Humans; Injections; Male; Meniere | 2000 |
Electrocochleography and gentamicin therapy for Ménière's disease: a preliminary report.
Topics: Acoustic Impedance Tests; Analysis of Variance; Anti-Bacterial Agents; Audiometry; Audiometry, Evoke | 2000 |
Pressure treatment versus gentamicin for Meniere's disease.
Topics: Adult; Audiometry, Pure-Tone; Caloric Tests; Female; Gentamicins; Humans; Hydrostatic Pressure; Male | 2001 |
Treatment of Menière's disease with topical gentamicin: a preliminary report.
Topics: Administration, Topical; Caloric Tests; Catheterization; Contraindications; Ear, Middle; Follow-Up S | 1992 |
Intratympanic gentamicin therapy for Menière's disease placed by a tubal catheter with systematic isosorbide.
Topics: Adult; Aged; Catheterization; Drug Therapy, Combination; Ear, Middle; Eustachian Tube; Female; Follo | 1991 |
256 other studies available for gentamicin and Meniere Disease
| Article | Year |
|---|---|
Duration of symptom control following intratympanic dexamethasone injections in Meniere's disease.
Topics: Anti-Bacterial Agents; Autoimmune Diseases; Dexamethasone; Gentamicins; Humans; Meniere Disease; Ret | 2022 |
[Consensus on intratympanic drug delivery for Menière's disease].
Topics: Anti-Bacterial Agents; Consensus; Gentamicins; Humans; Meniere Disease; Vertigo | 2022 |
Vestibular and audiometric results after endolymphatic mastoid shunt surgery in patients with Menière's disease.
Topics: Endolymphatic Shunt; Gentamicins; Humans; Mastoid; Meniere Disease; Retrospective Studies; Vertigo; | 2023 |
A comparison of endolymphatic shunt surgery and intratympanic gentamicin for meniere's disease.
Topics: Audiometry, Pure-Tone; Endolymphatic Shunt; Female; Gentamicins; Humans; Male; Meniere Disease; Midd | 2020 |
Change of VOR gain and pure-tone threshold after single low-dose intratympanic gentamicin injection in Meniere's disease.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry, Pure-Tone; Auditory Threshold; Ge | 2020 |
Letter to Editor concerning the "Therapeutic strategies in the treatment of Meniere's disease: the Italian Experience".
Topics: Endolymphatic Hydrops; Gentamicins; Humans; Italy; Meniere Disease; Saccule and Utricle | 2020 |
The Effect of Patient Volume and Experience on Management of Menière's Disease.
Topics: Endolymphatic Sac; Gentamicins; Humans; Meniere Disease; Otolaryngology; Otologic Surgical Procedure | 2020 |
On-Demand and Low Dose Intratympanic Gentamicin for Meniere's Disease: A Customized Approach.
Topics: Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Female; Gentamicins; Humans; Male; Meniere Disea | 2020 |
Intratympanic gentamycine for Ménière's disease: is there a selective vestibulotoxic effect?
Topics: Anti-Bacterial Agents; Audiometry, Pure-Tone; Gentamicins; Hearing Loss; Humans; Meniere Disease; Tr | 2020 |
Clinical Practice Guideline: Ménière's Disease.
Topics: Audiometry; Counseling; Diagnosis, Differential; Diuretics; Ear, Inner; Gentamicins; Glucocorticoids | 2020 |
Letter to the Editor: Intratympanic gentamicin for Ménière's disease: is there a selective vestibulotoxic effect?
Topics: Audiometry, Pure-Tone; Gentamicins; Humans; Meniere Disease; Vertigo | 2020 |
The author's reply regarding "Intratympanic gentamycine for Ménière's disease: is there a selective vestibulotoxic effect?"
Topics: Audiometry, Pure-Tone; Gentamicins; Humans; Meniere Disease | 2020 |
Transmastoid Labyrinthectomy for Menière's Disease: Experience and Outcomes.
Topics: Endolymphatic Sac; Gentamicins; Humans; Meniere Disease; Otologic Surgical Procedures; Retrospective | 2020 |
Effectiveness of Intratympanic Administration of Gentamicin in Unilateral MeniÈre's Disease.
Topics: Adrenal Cortex Hormones; Aminoglycosides; Anti-Bacterial Agents; Gentamicins; Humans; Meniere Diseas | 2020 |
Response to Letter to the Editor: "Effectiveness of Intratympanic Administration of Gentamicin in Unilateral meniÈre's Disease".
Topics: Adrenal Cortex Hormones; Aminoglycosides; Anti-Bacterial Agents; Gentamicins; Humans; Meniere Diseas | 2020 |
Triple Canal Occlusion for the Treatment of Intractable Menière's Disease.
Topics: Endolymphatic Sac; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Aged; Otologic Surgica | 2021 |
Effects of an Intratympanic Injection of Dexamethasone Combined with Gentamicin on the Expression Level of Serum P0 Protein Antibodies in Patients with Meniere's Disease.
Topics: Anti-Bacterial Agents; Dexamethasone; Gentamicins; Humans; Injection, Intratympanic; Meniere Disease | 2020 |
Intratympanic gentamicin injection for refractory ménière's disease (MD) has potential effect in preventing contralateral MD occurrence.
Topics: Adult; Aged; Caloric Tests; Female; Gentamicins; Hearing Loss; Humans; Injection, Intratympanic; Mal | 2021 |
Efficacy of Intratympanic Gentamicin in Menière's Disease With and Without Migraine.
Topics: Adult; Aged; Anti-Bacterial Agents; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Aged; | 2017 |
Navigating the challenges of Meniere disease.
Topics: Gentamicins; Humans; Injection, Intratympanic; Male; Meniere Disease; Middle Aged; Nursing Assessmen | 2017 |
Selective Window Application of Gentamicin+ Dexamethasone in Meniere's Disease.
Topics: Anti-Bacterial Agents; Audiometry, Pure-Tone; Auditory Threshold; Caloric Tests; Dexamethasone; Drug | 2017 |
The Degeneration of the Vestibular Efferent Neurons After Intratympanic Gentamicin Administration.
Topics: Animals; Anti-Bacterial Agents; Female; Fluorescent Antibody Technique; Gentamicins; Guinea Pigs; Im | 2018 |
[Small doses of gentamicin drum indoor injection treatment of intractableMénière disease clinical observation of the impact of the hearing].
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Audiometry, Speech; Female; Gentamicins; | 2016 |
[Small doses of gentamicin drum indoor injection treatment of intractableMénière disease clinical observation of the impact of the hearing].
Topics: Adolescent; Adult; Anti-Bacterial Agents; Audiometry, Pure-Tone; Bone Conduction; Ear Ossicles; Fema | 2016 |
Vitamin D supplementation may improve symptoms in Meniere's disease.
Topics: Anti-Bacterial Agents; Autoimmunity; Cytokines; Dietary Supplements; Gentamicins; Humans; Inflammati | 2018 |
Low Concentration Intra-Tympanic Gentamicin Treatment for Menière's Disease: A Long-Term Follow Up.
Topics: Anti-Bacterial Agents; Cohort Studies; Female; Follow-Up Studies; Gentamicins; Humans; Injections; M | 2018 |
Cochlear-Internal Canal and Cochlear-Facial Dehiscence: A Novel Entity.
Topics: Anti-Bacterial Agents; Cerebrospinal Fluid Leak; Cochlea; Cochlear Implantation; Ear Canal; Gentamic | 2018 |
Intratympanic Therapies in Ménière Disease: Evaluation of Outcomes and Early Vertigo Control.
Topics: Adult; Audiometry, Pure-Tone; Dexamethasone; Female; Gentamicins; Glucocorticoids; Humans; Injection | 2019 |
Delayed Effect and Gain Restoration After Intratympanic Gentamicin for Menière's Disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Caloric Tests; Female; Gentamicins; Humans; Injection, Intratymp | 2019 |
Tenotomy of the middle ear muscles : An unknown surgical approach in Meniere's disease.
Topics: Adult; Ear, Middle; Female; Gentamicins; Humans; Meniere Disease; Tenotomy; Treatment Outcome; Verti | 2019 |
Gentamicin delivery to the inner ear: Does endolymphatic hydrops matter?
Topics: Animals; Auditory Threshold; Contrast Media; Disease Models, Animal; Ear, Inner; Ear, Middle; Endoly | 2018 |
Clinical features and management of Meniere's disease patients with drop attacks.
Topics: Adult; Case-Control Studies; Endolymphatic Hydrops; Female; Gentamicins; Hearing; Hearing Loss; Hear | 2019 |
Long-term Vertigo Control and Vestibular Function After Low-dose On-demand Transtympanic Gentamicin for Refractory Menière's Disease.
Topics: Adult; Anti-Bacterial Agents; Caloric Tests; Female; Gentamicins; Humans; Injection, Intratympanic; | 2019 |
Long-Term Follow-Up of Intratympanic Methylprednisolone Versus Gentamicin in Patients With Unilateral Menière's Disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Ear, Inner; Female; Follow-Up Studies; Gentamicins; Humans; Inje | 2019 |
CASP9 genotype confers gentamicin susceptibility in intratympanic treatment of intractable vertigo caused by Ménière's disease.
Topics: Adult; Aged; Aged, 80 and over; Caspase 9; Female; Follow-Up Studies; Gentamicins; Humans; Injection | 2019 |
Therapeutic strategies in the treatment of Menière's disease: the Italian experience.
Topics: Betahistine; Cross-Cultural Comparison; Diet, Sodium-Restricted; Gentamicins; Glucocorticoids; Human | 2019 |
Patient Perceptions of Effectiveness in Treatments for Menière's Disease: a National Survey in Italy.
Topics: Absenteeism; Anti-Bacterial Agents; Betahistine; Cross-Sectional Studies; Diet Therapy; Diuretics; F | 2019 |
Intratympanic gentamicin treatment 'as needed' for Meniere's disease. Long-term analysis using the Kaplan-Meier method.
Topics: Adult; Aged; Anti-Bacterial Agents; Drug Administration Schedule; Female; Gentamicins; Humans; Kapla | 2014 |
Comparison of intratympanic methylprednisolone and gentamicin for Meniere's disease may be misleading.
Topics: Anti-Bacterial Agents; Female; Gentamicins; Glucocorticoids; Humans; Male; Meniere Disease; Methylpr | 2013 |
Response to: Comparison of intratympanic methylprednisolone and gentamicin for Meniere's disease may be misleading.
Topics: Anti-Bacterial Agents; Female; Gentamicins; Glucocorticoids; Humans; Male; Meniere Disease; Methylpr | 2013 |
Endolymphatic sac surgery versus intratympanic gentamicin for the treatment of intractable Ménière's disease: a retrospective review with survey.
Topics: Adult; Anti-Bacterial Agents; Endolymphatic Sac; Female; Gentamicins; Hearing Tests; Humans; Male; M | 2013 |
Gentamicin administration on the stapes footplate causes greater hearing loss and vestibulotoxicity than round window administration in guinea pigs.
Topics: Animals; Anti-Bacterial Agents; Cochlea; Evoked Potentials, Auditory, Brain Stem; Female; Gentamicin | 2013 |
Preclinical and clinical studies of unrelieved aural fullness following intratympanic gentamicin injection in patients with intractable Ménière's disease.
Topics: Adult; Animals; Anti-Bacterial Agents; Female; Gentamicins; Guinea Pigs; Humans; Male; Meniere Disea | 2013 |
[What helps better: intratympanic gentamicin or methylprednisolone?].
Topics: Anti-Bacterial Agents; Female; Gentamicins; Glucocorticoids; Humans; Male; Meniere Disease; Methylpr | 2013 |
Middle ear gentamicin-soaked pledgets in the treatment of Ménière's disease.
Topics: Anti-Bacterial Agents; Drug Delivery Systems; Ear, Middle; Female; Gentamicins; Hearing Loss; Humans | 2014 |
Intratympanic gentamicin for Meniere's disease: short- and long-term follow-up of two regimens of treatment.
Topics: Anti-Bacterial Agents; Female; Follow-Up Studies; Gentamicins; Humans; Male; Meniere Disease; Middle | 2014 |
Chemical labyrinthectomy for the worse ear of adult Nigerians with bilateral Meniere's disease: preliminary report of treatment outcomes.
Topics: Anti-Bacterial Agents; Audiometry, Pure-Tone; Ear, Inner; Female; Gentamicins; Humans; Injection, In | 2015 |
Intratympanic gentamicin as a treatment for drop attacks in patients with Meniere's disease.
Topics: Adult; Aged; Aged, 80 and over; Ear, Middle; Female; Gentamicins; Humans; Injections; Male; Meniere | 2014 |
Comparison of second-echelon treatments for Ménière's disease.
Topics: Aged; Anti-Bacterial Agents; Decompression, Surgical; Diet, Sodium-Restricted; Diuretics; Endolympha | 2014 |
Management of intractable Ménière's disease after intratympanic injection of gentamicin.
Topics: Adult; Aged; Cohort Studies; Endolymphatic Hydrops; Female; Follow-Up Studies; Gentamicins; Hearing | 2015 |
Single intratympanic gentamicin injection in Ménière's disease: VOR change and prognostic usefulness.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Female; Follow-Up Studies; Gentamicins; Human | 2015 |
Binocular vertical diplopia following chemical labyrinthectomy with gentamicin: A case report and review of literature.
Topics: Aged; Diplopia; Ear, Inner; Female; Gentamicins; Humans; Meniere Disease; Nucleic Acid Synthesis Inh | 2016 |
Cell-specific accumulation patterns of gentamicin in the guinea pig cochlea.
Topics: Animals; Biological Transport, Active; Cochlea; Gap Junctions; Gentamicins; Guinea Pigs; Humans; Imm | 2015 |
Is low-dose intratympanic gentamicin an effective treatment for Ménière's disease: the Birmingham experience.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry, Pure-Tone; Cohort Studies; Female | 2015 |
Modified titration intratympanic gentamicin injection for unilateral intractable Ménière's disease.
Topics: Adult; Drug Administration Schedule; Ear, Inner; Female; Follow-Up Studies; Gentamicins; Hearing; Hu | 2015 |
Vestibular results after intratympanic gentamicin therapy in disabling Menière's disease.
Topics: Anti-Bacterial Agents; Case-Control Studies; Female; Gentamicins; Humans; Injection, Intratympanic; | 2016 |
Assessment of Vestibulo-oculomotor Reflex in Ménière's Disease: Defining an Instrumental Profile.
Topics: Adult; Aged; Caloric Tests; Female; Gentamicins; Head Impulse Test; Humans; Injection, Intratympanic | 2016 |
End-point indicators of low-dose intra-tympanic gentamicin in management of Ménière's disease.
Topics: Adult; Aged; Female; Gentamicins; Head Impulse Test; Humans; Injection, Intratympanic; Male; Meniere | 2017 |
Perilymph pharmacokinetics of locally-applied gentamicin in the guinea pig.
Topics: Animals; Gentamicins; Guinea Pigs; Humans; Meniere Disease; Models, Biological; Perilymph; Round Win | 2016 |
Intratympanic steroids injection is effective for the treatment of drop attacks with Ménière's disease and delayed endolymphatic hydrops: A retrospective study.
Topics: Adult; Anti-Bacterial Agents; Dexamethasone; Drug Therapy, Combination; Endolymphatic Hydrops; Femal | 2016 |
Intratympanal gentamicin in Meniere's disease: Effects on individual semicircular canals.
Topics: Adult; Female; Gentamicins; Head Impulse Test; Humans; Injection, Intratympanic; Male; Meniere Disea | 2018 |
Transtympanic gentamicin treatment using Silverstein MicroWick in Ménière's disease patients: long term outcome.
Topics: Adult; Aged; Anti-Bacterial Agents; Drug Delivery Systems; Ear, Middle; Female; Gentamicins; Hearing | 2009 |
Gentamicin injections for Ménière disease: comparison of subjective and objective end points.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Female; Gentamicins; Health Status Indicators | 2008 |
Hearing results following intratympanic gentamicin perfusion for Ménière's disease.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry, Pure-Tone; Female; Ge | 2009 |
Contemporary role of endolymphatic mastoid shunt surgery in the era of transtympanic perfusion strategies.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Ear, Inner; Endolymphatic Shunt; Female; Follow-Up S | 2008 |
Time course of repeated intratympanic gentamicin for Ménière's disease.
Topics: Anti-Bacterial Agents; Disease-Free Survival; Drug Administration Schedule; Gentamicins; Humans; Inj | 2009 |
Disability in patients with Menière's disease following the use of two different treatment modalities: betahistine and intratympanic gentamicin.
Topics: Administration, Oral; Administration, Topical; Betahistine; Disability Evaluation; Ear, Middle; Gent | 2008 |
Tenotomy of the tensor tympani and stapedius tendons in Ménière's disease.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Dizziness; Ear, Middle; Female; Gentamicins; Humans; | 2009 |
Middle ear exploration in patients with Ménière's disease who have failed outpatient intratympanic gentamicin therapy.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Care; Anti-Bacterial Agents; Audiometry; Ear, Middle; Fem | 2009 |
High-dose intratympanic gentamicin instillations for treatment of Meniere's disease: long-term results.
Topics: Adult; Aged; Female; Follow-Up Studies; Gentamicins; Hearing Loss; Humans; Male; Meniere Disease; Mi | 2009 |
Vestibular function and vertigo control after intratympanic gentamicin for Ménière's disease.
Topics: Anti-Bacterial Agents; Caloric Tests; Chi-Square Distribution; Databases, Factual; Drug Administrati | 2009 |
Intractable Ménière's disease. Modelling of the treatment by means of statistical analysis.
Topics: Administration, Topical; Adult; Anti-Bacterial Agents; Diagnosis, Differential; Disability Evaluatio | 2010 |
Intratympanic gentamicin treatment of patients with Ménière's disease with normal hearing.
Topics: Adult; Aged; Aged, 80 and over; Audiometry; Audiometry, Pure-Tone; Caloric Tests; Electronystagmogra | 2010 |
Evidence-based modification of intratympanic gentamicin injections in patients with intractable vertigo.
Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Biological Availability; Ear, Middle; Gentamic | 2010 |
Outcomes of endolymphatic shunt surgery for Ménière's disease: comparison with intratympanic gentamicin on vertigo control and hearing loss.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Chi-Square Distribution; Ear, Inner; Endo | 2010 |
Results of electrocochleography in Ménière's disease after successful vertigo control by single intratympanic gentamicin injection.
Topics: Adult; Aged; Aged, 80 and over; Audiometry, Evoked Response; Audiometry, Pure-Tone; Cochlea; Female; | 2011 |
A controlled and sustained local gentamicin delivery system for inner ear applications.
Topics: Absorbable Implants; Animals; Anti-Bacterial Agents; Delayed-Action Preparations; Drug Delivery Syst | 2010 |
Comparison of gentamicin distribution in the inner ear following administration via the endolymphatic sac or round window.
Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Cochlea; Endolymphatic Sac; Evoked Potentia | 2010 |
Intratympanic gentamicin injections for the treatment of Ménière's disease.
Topics: Adult; Aged; Aged, 80 and over; Audiometry, Pure-Tone; Female; Gentamicins; Hearing Disorders; Human | 2010 |
Surgical indication in Menière's disease therapy: clinical and epidemiological aspects.
Topics: Adult; Aged; Female; Gentamicins; Humans; Male; Meniere Disease; Microinjections; Middle Aged; Patie | 2011 |
Treatment of Ménière's disease with "on-demand" intratympanic gentamicin injections.
Topics: Adult; Anti-Bacterial Agents; Drug Administration Schedule; Female; Gentamicins; Humans; Injections; | 2011 |
Skew deviation after intratympanic gentamicin therapy.
Topics: Aged; Anti-Bacterial Agents; Diplopia; Ear, Middle; Female; Gentamicins; Humans; Injections; Male; M | 2011 |
Does intratympanic gadolinium injection predict efficacy of gentamicin partial chemolabyrinthectomy in Menière's disease patients?
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Evoked Response; Contrast Media; Ear, Inner; Ear, Mi | 2012 |
[Air conducted ocular VEMP: II. First clinical investigations].
Topics: Acoustic Stimulation; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Female; Gentamicins; Hu | 2011 |
'PREHAB': Vestibular prehabilitation to ameliorate the effect of a sudden vestibular loss.
Topics: Adult; Aged; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Aged; Preoperative Care; Pro | 2011 |
'PREHAB': Vestibular prehabilitation to ameliorate the effect of a sudden vestibular loss.
Topics: Adult; Aged; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Aged; Preoperative Care; Pro | 2011 |
'PREHAB': Vestibular prehabilitation to ameliorate the effect of a sudden vestibular loss.
Topics: Adult; Aged; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Aged; Preoperative Care; Pro | 2011 |
'PREHAB': Vestibular prehabilitation to ameliorate the effect of a sudden vestibular loss.
Topics: Adult; Aged; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Aged; Preoperative Care; Pro | 2011 |
[Transtympanic gentamicin in Ménière's disease: evaluation of the quality of life].
Topics: Adult; Aged; Female; Follow-Up Studies; Gentamicins; Humans; Male; Meniere Disease; Middle Aged; Qua | 2001 |
Cochlear function in Ménière's disease.
Topics: Adult; Aged; Aged, 80 and over; Audiometry, Evoked Response; Cochlea; Female; Gentamicins; Humans; I | 2012 |
Magnetic resonance imaging fails to show evidence of reduced endolymphatic hydrops in gentamicin treatment of Ménière's disease.
Topics: Adult; Aged; Ear, Inner; Endolymphatic Hydrops; Female; Gentamicins; Humans; Image Processing, Compu | 2012 |
Variability in the perilymphatic diffusion of gadolinium does not predict the outcome of intratympanic gentamicin in patients with Ménière's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Contrast Media; Endolymph; Female; Follow-Up Studies; Gadolinium | 2012 |
Distribution of gentamicin in inner ear after local administration via a chitosan glycerophosphate hydrogel delivery system.
Topics: Animals; Anti-Bacterial Agents; Chitosan; Delayed-Action Preparations; Drug Delivery Systems; Ear, I | 2012 |
Mitochondrial ribosome and Ménière's disease: a pilot study.
Topics: Adult; Aged; DNA-Binding Proteins; Female; Genes, Mitochondrial; Genes, rRNA; Genetic Predisposition | 2012 |
Intratympanic gentamicin treatment for unilateral Ménière's disease: long-term follow up of a proven regime.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Dose-Response Relationship, Drug; Female; | 2013 |
The effect of intratympanic methylprednisolone and gentamicin injection on Ménière's disease.
Topics: Anti-Bacterial Agents; Audiometry, Pure-Tone; Female; Gentamicins; Glucocorticoids; Hearing Loss; Hu | 2013 |
Intentional ablation of vestibular function using commercially available topical gentamicin-betamethasone eardrops in patients with Meniere's disease: further evidence for topical eardrop ototoxicity.
Topics: Administration, Topical; Anti-Bacterial Agents; Betamethasone; Female; Gentamicins; Glucocorticoids; | 2002 |
Benign paroxysmal positional vertigo in patients with Ménière's disease treated with intratympanic gentamycin.
Topics: Adult; Aged; Anti-Bacterial Agents; Female; Follow-Up Studies; Gentamicins; Humans; Male; Meniere Di | 2002 |
Efficacy of increased gentamicin concentration for intratympanic injection therapy in Ménière's disease.
Topics: Caloric Tests; Deafness; Dose-Response Relationship, Drug; Female; Gentamicins; Hearing; Humans; Inj | 2002 |
[Intra-tympanic gentamicin in the treatment of Ménière's disease: preliminary results ].
Topics: Adult; Audiometry, Pure-Tone; Audiometry, Speech; Drug Evaluation; Ear, Middle; Female; Gentamicins; | 2002 |
New treatment for Ménière's disease.
Topics: Adult; Anti-Bacterial Agents; Gentamicins; Humans; Instillation, Drug; Meniere Disease; Otologic Sur | 2002 |
Round window gentamicin absorption: an in vivo human model.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Female; Gentamicins; Humans; Male; Meniere Di | 2002 |
[Intratympanic gentamycin in association with human fibrin glue in the treatment of Meniere's disease: preliminary results].
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug Combinations; F | 2002 |
New treatment for Meniére's disease.
Topics: Anti-Bacterial Agents; Australia; Gentamicins; Humans; Meniere Disease | 2002 |
Changes in the three-dimensional angular vestibulo-ocular reflex following intratympanic gentamicin for Ménière's disease.
Topics: Adult; Aged; Cold Temperature; Female; Gentamicins; Head; Humans; Male; Meniere Disease; Middle Aged | 2002 |
Revision of endolymphatic sac surgery for recurrent Meniere's disease.
Topics: Adult; Anti-Bacterial Agents; Audiometry; Endolymphatic Sac; Follow-Up Studies; Gentamicins; Humans; | 2002 |
[Gentamicin for the transtympanic treatment of Menière's disease].
Topics: Adult; Aged; Female; Follow-Up Studies; Gentamicins; Humans; Injections, Intralesional; Male; Menier | 2001 |
Gentamicin tympanoclysis: effects on the labyrinthine sensory cells.
Topics: Acoustic Maculae; Animals; Anti-Bacterial Agents; Ataxia; Cats; Ear, Middle; Gentamicins; Hair Cells | 2003 |
Gentamicin perfusion vestibular response and hearing loss.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry, Pure-Ton | 2003 |
Changing trends in the surgical treatment of Ménière's disease: results of a 10-year survey.
Topics: Anti-Bacterial Agents; Ear, Inner; Endolymphatic Sac; Gentamicins; Humans; Meniere Disease; Otologic | 2003 |
What is Meniere's disease, and how is it treated?
Topics: Anti-Bacterial Agents; Equipment Design; Gentamicins; Humans; Meniere Disease; Otolaryngology | 2003 |
Long-term hearing outcome in patients receiving intratympanic gentamicin for Ménière's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Female; Follow-Up Studies; Gentamicins; H | 2003 |
Results of vestibular autorotation testing at the end of intratympanic gentamicin treatment for Ménière's disease.
Topics: Anti-Bacterial Agents; Audiometry; Female; Gentamicins; Humans; Injections; Male; Meniere Disease; M | 2003 |
Intratympanic gentamicin for Ménière's disease; a survey of current UK practice.
Topics: Anti-Bacterial Agents; Clinical Protocols; Drug Administration Routes; Gentamicins; Health Care Surv | 2003 |
[Curative effect of transtympanic perfusion of gentamicin on unilateral Ménière's disease].
Topics: Adult; Audiometry, Pure-Tone; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Aged; Tympa | 2003 |
Hearing loss after intratympanic gentamicin therapy for unilateral Ménière's Disease.
Topics: Audiometry; Drug Administration Schedule; Ear, Middle; Female; Follow-Up Studies; Gentamicins; Heari | 2003 |
[Transtympanic administration of gentamicin in Menière diseases--less is more!?].
Topics: Anti-Bacterial Agents; Deafness; Dose-Response Relationship, Drug; Drug Administration Schedule; Ear | 2003 |
[Intratympanic interval therapy of Menière disease with gentamicin with preserving cochlear function].
Topics: Anti-Bacterial Agents; Audiometry, Pure-Tone; Audiometry, Speech; Caloric Tests; Cochlea; Deafness; | 2003 |
Long-term results after interval therapy with intratympanic gentamicin for Menière's disease.
Topics: Anti-Bacterial Agents; Drug Administration Schedule; Female; Follow-Up Studies; Gentamicins; Humans; | 2004 |
[Intratympanic gentamicin treatment for intractable Menière's disease].
Topics: Anti-Bacterial Agents; Female; Follow-Up Studies; Gentamicins; Humans; Injections; Male; Meniere Dis | 2004 |
Vestibular nerve section versus intratympanic gentamicin for Meniere's disease.
Topics: Anti-Bacterial Agents; Audiometry, Pure-Tone; Gentamicins; Humans; Injections; Meniere Disease; Post | 2004 |
The early kinetics of gentamicin uptake into the inner ear.
Topics: Animals; Anti-Bacterial Agents; Chinchilla; Delayed-Action Preparations; Ear, Inner; Gentamicins; Im | 2002 |
Intratympanic gentamicin for intractable Meniere's disease: 5-year follow-up.
Topics: Anti-Bacterial Agents; Caloric Tests; Disability Evaluation; Ear, Middle; Female; Follow-Up Studies; | 2003 |
[Intratympanic gentamicin in Menière's disease].
Topics: Adult; Audiometry, Pure-Tone; Auditory Threshold; Ear, Middle; Female; Follow-Up Studies; Gentamicin | 2004 |
Vestibular destruction by slow infusion of gentamicin into semicircular canals.
Topics: Animals; Anti-Bacterial Agents; Chinchilla; Dose-Response Relationship, Drug; Gentamicins; Hair Cell | 2004 |
Vestibular function and vasopressin.
Topics: Animals; Anti-Bacterial Agents; Cold Temperature; Drainage; Electric Stimulation; Endolymphatic Sac; | 2004 |
The status of the contralateral ear in established unilateral Menière's disease.
Topics: Adult; Anti-Bacterial Agents; Audiometry; Auditory Threshold; Female; Gentamicins; Hearing Loss; Hum | 2004 |
Long-term results of gentamicin inner ear perfusion in Ménière's disease.
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Caloric Tests; Catheters, Indwelling; D | 2004 |
Silverstein MicroWick.
Topics: Administration, Topical; Anti-Bacterial Agents; Dexamethasone; Gentamicins; Glucocorticoids; Hearing | 2004 |
Surgical management of Meniere's disease in the era of gentamicin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Audiometry, Pure-Tone; Dizziness; Female; Gentamicins; H | 2005 |
A national survey amongst UK otolaryngologists regarding the treatment of Ménière's disease.
Topics: Anti-Bacterial Agents; Betahistine; Clinical Protocols; Consultants; Diuretics; Gentamicins; Health | 2005 |
[Use of intratympanic gentamycin for the treatment of Meniere's disease].
Topics: Aged; Anti-Bacterial Agents; Caloric Tests; Female; Gentamicins; Humans; Male; Meniere Disease; Micr | 2001 |
Intratympanic gentamicin in monolateral Meniere's disease: our experience.
Topics: Adult; Aged; Anti-Bacterial Agents; Ear, Middle; Female; Gentamicins; Humans; Injections; Male; Meni | 2006 |
[Long-term results of transtympanic gentamicin treatment in Meniere's disease].
Topics: Adult; Anti-Bacterial Agents; Female; Follow-Up Studies; Gentamicins; Hearing; Humans; Injections; M | 2005 |
Meta-analysis of intratympanic gentamicin.
Topics: Anti-Bacterial Agents; Gentamicins; Humans; Meniere Disease; Meta-Analysis as Topic; Tympanic Membra | 2005 |
VEMPs and dynamic posturography after intratympanic gentamycin in Menière's disease.
Topics: Adult; Aged; Evoked Potentials, Auditory; Female; Gentamicins; Humans; Male; Meniere Disease; Middle | 2005 |
Angular vestibulo-ocular reflex gains correlate with vertigo control after intratympanic gentamicin treatment for Meniere's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Caloric Tests; Gentamicins; Humans; Injections, Intralesional; M | 2005 |
Meniett therapy: rescue treatment in severe drug-resistant Ménière's disease?
Topics: Adult; Drug Resistance, Microbial; Female; Follow-Up Studies; Gentamicins; Humans; Injections, Intra | 2005 |
Intratympanic gentamicin treatment after endolymphatic sac surgery.
Topics: Adult; Aged; Audiometry, Pure-Tone; Auditory Threshold; Ear, Middle; Electronystagmography; Endolymp | 2005 |
[Vertigo attacks -- current therapy].
Topics: Acetazolamide; Adult; Aged; Betahistine; Dexamethasone; Ear, Middle; Gentamicins; Humans; Injections | 2005 |
Outcomes in the use of intra-tympanic gentamicin in the treatment of Ménière's disease.
Topics: Anti-Bacterial Agents; Female; Gelatin Sponge, Absorbable; Gentamicins; Hearing Loss; Humans; Male; | 2006 |
Surgical management of Meniere's disease in the era of gentamicin.
Topics: Administration, Topical; Anti-Bacterial Agents; Ear Canal; Follow-Up Studies; Gentamicins; Humans; M | 2005 |
[Skull vibratory test in partial vestibular lesions--influence of the stimulus frequency on the nystagmus direction].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Caloric Tests; Case-Control Studies; Female; Gentami | 2005 |
[Vestibular neurotomy versus chemical labyrinthectomy for disabling Menière disease].
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Disability Evaluation; Ear, Inner; Female | 2005 |
Intratympanic gentamicin for Ménière's disease: effect on quality of life as assessed by Glasgow benefit inventory.
Topics: Adult; Aged; Anti-Bacterial Agents; Female; Gentamicins; Humans; Injections; Male; Meniere Disease; | 2006 |
Drop attacks and vertical vertigo after transtympanic gentamicin: diagnosis and management.
Topics: Administration, Topical; Aged; Female; Gentamicins; Humans; Meniere Disease; Paralysis; Syncope; Tym | 2005 |
Factors relating to the vertigo control and hearing changes following intratympanic gentamicin for intractable Ménière's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Evoked Response; Female; Gentamicins; Hearing Loss; | 2006 |
Intratympanic gentamicin treatment in Meniere's disease: patients' experiences and outcomes.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry, Pure-Tone; Auditory Threshold; Fe | 2006 |
Transtympanic gentamicin treatment in Meniere's disease: a preliminary report.
Topics: Adult; Aged; Audiometry, Pure-Tone; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Aged; | 2006 |
Long-term follow-up after gentamicin application via the Silverstein MicroWick in the treatment of Ménière's disease.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug Delivery System | 2006 |
Auditory results after vestibular nerve section and intratympanic gentamicin for Ménière's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Female; Gentamicins; Hearing Loss, Sensor | 2007 |
Histopathology of the vestibular end organs after intratympanic gentamicin failure for Meniere's disease.
Topics: Administration, Topical; Anti-Bacterial Agents; Atrophy; Ear, Inner; Gentamicins; Hair Cells, Audito | 2007 |
Low dose transtympanic gentamicin treatment for intractable Meniere's disease: a prospective study.
Topics: Anti-Bacterial Agents; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Aged; Prospective | 2007 |
Current management of Ménière's disease in an only hearing ear.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Decompression, Surgical; Endolymphatic Sac; Feeding | 2007 |
Intratympanic gentamicin therapy for intractable Ménière's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Caloric Tests; Drug Administration Schedu | 2007 |
[The effects of small dose of intratympanic gentamicin injection on intractable Meniere's disease].
Topics: Adolescent; Adult; Aged; Ear, Middle; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Age | 2007 |
Long-term disability of class A patients with Ménière's disease after treatment with intratympanic gentamicin.
Topics: Anti-Bacterial Agents; Audiometry, Pure-Tone; Disability Evaluation; Ear, Middle; Female; Follow-Up | 2007 |
Effects of a single intratympanic gentamicin injection on Meniere's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Caloric Tests; Dose-Response Relationship | 2007 |
Treatment of Ménière's disease by low-dosage intratympanic gentamicin application: effect on otolith function.
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Elect | 2007 |
Long-term vertigo control in patients after intratympanic gentamicin instillation for Ménière's disease.
Topics: Adult; Anti-Bacterial Agents; Caloric Tests; Dizziness; Drug Implants; Ear, Middle; Electronystagmog | 2007 |
Longitudinal results with intratympanic dexamethasone in the treatment of Ménière's disease.
Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents; Audiometry; Dexamethasone; Drug Resistance; Follow- | 2008 |
Comparisons of cochleotoxicity among three gentamicin compounds following intratympanic application.
Topics: Animals; Ear, Middle; Evoked Potentials, Auditory, Brain Stem; Gentamicins; Hair Cells, Auditory, Ou | 2008 |
Reliability of the vestibular evoked myogenic potential test in assessing intratympanic gentamicin therapy in Meniere's disease.
Topics: Adult; Audiometry, Pure-Tone; Dose-Response Relationship, Drug; Evoked Potentials, Somatosensory; Fe | 2008 |
Oculomotor findings mimicking a cerebellar disorder and postural control in severe Meniere's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Case-Control Studies; Gentamicins; Humans; Meniere Disease; Midd | 2009 |
Sac surgery on the only or better hearing ear.
Topics: Adult; Cochlea; Deafness; Ear, Inner; Endolymphatic Sac; Female; Gentamicins; Humans; Iatrogenic Dis | 1983 |
[Treatment of Ménière's disease with intratympanically applied gentamycin sulphate (author's transl)].
Topics: Ear, Middle; Female; Gentamicins; Humans; Male; Meniere Disease; Tinnitus; Vertigo | 1982 |
[The indications for middle ear instillation of gentamicin in Menière's disease (author's transl)].
Topics: Ear, Middle; Gentamicins; Humans; Meniere Disease; Tinnitus; Vertigo | 1981 |
[Treatment of Morbus Menière with intratympanally applied Gentamycin (author's transl)].
Topics: Administration, Topical; Adolescent; Adult; Aged; Child; Ear, Middle; Gentamicins; Humans; Meniere D | 1980 |
Transtympanic gentamycin in the treatment of Ménière's disease.
Topics: Ear, Middle; Gentamicins; Humans; Instillation, Drug; Meniere Disease | 1995 |
Indications and results of gentamycin injection into the middle ear of patients with meniére's disease.
Topics: Adult; Aged; Drainage; Ear, Middle; Endolymphatic Sac; Gentamicins; Humans; Injections; Meniere Dise | 1995 |
Intratympanic gentamicin treatment: preliminary results in two patients with Menière's disease.
Topics: Audiometry, Pure-Tone; Auditory Threshold; Endolymphatic Hydrops; Gentamicins; Hearing Loss, Sensori | 1995 |
[Continuous intratympanic gentamycin infusion in Menière disease].
Topics: Adult; Audiometry, Pure-Tone; Auditory Threshold; Dose-Response Relationship, Drug; Drug Administrat | 1994 |
[Menière's disease].
Topics: Follow-Up Studies; Gentamicins; Humans; Meniere Disease; Remission, Spontaneous | 1994 |
Pharmacologic labyrinthectomy.
Topics: Aminoglycosides; Ear, Inner; Gentamicins; Humans; Meniere Disease; Streptomycin; Vertigo | 1994 |
Intratympanic gentamicin in bilateral Menière's disease.
Topics: Adolescent; Adult; Caloric Tests; Child; Ear, Inner; Electronystagmography; Female; Functional Later | 1994 |
Irritative spontaneous nystagmus following intratympanic gentamicin for Menière's disease.
Topics: Adult; Aged; Ear, Inner; Ear, Middle; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Age | 1993 |
[Subablative gentamycin therapy in Menière's disease].
Topics: Audiometry, Pure-Tone; Auditory Threshold; Caloric Tests; Dose-Response Relationship, Drug; Drug Adm | 1993 |
[27 years experiences with transtympanic aminoglycoside treatment of Menière's disease].
Topics: Administration, Topical; Anti-Bacterial Agents; Auditory Threshold; Dose-Response Relationship, Drug | 1995 |
Intratympanic gentamicin therapy for Menière's disease: preliminary comparison of two regimens.
Topics: Audiometry, Pure-Tone; Caloric Tests; Clinical Protocols; Female; Gentamicins; Hearing Loss, Sensori | 1995 |
Effect of intratympanically administered gentamicin on hearing and tinnitus in Menière's disease.
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Auditory Thresho | 1995 |
Ocular torsion monitoring in chemical labyrinthectomy.
Topics: Adult; Aged; Audiometry, Pure-Tone; Electronystagmography; Fovea Centralis; Gentamicins; Hearing Dis | 1996 |
Topical gentamicin-induced hearing loss: a mitochondrial ribosomal RNA study of genetic susceptibility.
Topics: Adult; Aged; Anti-Bacterial Agents; Base Sequence; Female; Gene Amplification; Gentamicins; Hearing | 1996 |
Intratympanic gentamicin therapy for Ménière's disease.
Topics: Adult; Aged; Audiometry, Pure-Tone; Auditory Threshold; Female; Gentamicins; Hearing Disorders; Huma | 1997 |
Intratympanic gentamicin in Ménière's disease: results of therapy.
Topics: Adult; Aged; Audiometry, Pure-Tone; Caloric Tests; Ear, Inner; Female; Gentamicins; Hearing Disorder | 1997 |
Intratympanic gentamicin for treatment of intractable Meniere's disease: a preliminary report.
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Female; Gentamicins; Humans; Male; Meni | 1997 |
Low-dose intratympanic gentamicin and the treatment of Meniere's disease: preliminary results.
Topics: Absorption; Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Elec | 1997 |
When and how to use gentamicin in the treatment of Menière's disease.
Topics: Anti-Bacterial Agents; Gentamicins; Humans; Meniere Disease; Vertigo | 1997 |
Transtympanic gentamicin in the treatment of Meniére's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Endolymphatic Hydrops; Follow-Up Studies; Gentamicins; Humans; M | 1997 |
Inner ear perfusion and the role of round window patency.
Topics: Aged; Anti-Bacterial Agents; Chemotherapy, Cancer, Regional Perfusion; Endoscopy; Female; Gentamicin | 1997 |
[Intravenous gentamicin therapy in bilateral Menière disease].
Topics: Anti-Bacterial Agents; Auditory Threshold; Caloric Tests; Dose-Response Relationship, Drug; Drug Adm | 1997 |
Treatment of intractable Menière's disease with intratympanic gentamicin: review of the University of Ottawa experience.
Topics: Auditory Threshold; Ear, Middle; Female; Follow-Up Studies; Gentamicins; Humans; Infusions, Parenter | 1997 |
The current role of local intratympanic gentamicin therapy in the management of unilateral Menière's disease.
Topics: Anti-Bacterial Agents; Catheterization; Catheters, Indwelling; Ear, Inner; Ear, Middle; Female; Foll | 1998 |
Intratympanic gentamicin treatment for Meniere's disease.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry, Pure-Ton | 1998 |
Intratympanic gentamicin in Meniere's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry, Pure-Tone; Chi-Square Distribution; Electronystagmog | 1998 |
Intratympanic gentamicin injection for the treatment of Meniere's disease.
Topics: Anti-Bacterial Agents; Caloric Tests; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Age | 1998 |
A head autorotation test for patients with Menière's disease.
Topics: Adult; Aged; Aged, 80 and over; Caloric Tests; Combined Modality Therapy; Ear, Inner; Female; Gentam | 1998 |
Subjective visual horizontal during follow-up after unilateral vestibular deafferentation with gentamicin.
Topics: Afferent Pathways; Anti-Bacterial Agents; Caloric Tests; Electrooculography; Female; Follow-Up Studi | 1998 |
Transtympanic gentamicin for Meniere's syndrome.
Topics: Adult; Aged; Electronystagmography; Female; Gentamicins; Humans; Injections; Male; Meniere Disease; | 1998 |
[Gentamicin injection technique. A simplification of transtympanic therapy of Menière disease].
Topics: Anesthesia, Local; Female; Gentamicins; Humans; Injections; Male; Meniere Disease; Retreatment; Trea | 1998 |
Morphologic changes in the inner ear of Chinchilla laniger after middle ear administration of gentamicin in a sustained-release vehicle.
Topics: Animals; Anti-Bacterial Agents; Chinchilla; Delayed-Action Preparations; Disease Models, Animal; Dru | 1999 |
Postural compensation after intratympanic gentamicin treatment of Menière's disease.
Topics: Adult; Aged; Female; Follow-Up Studies; Gentamicins; Humans; Locomotion; Male; Meniere Disease; Midd | 1999 |
Intratympanic gentamicin titration therapy for intractable Meniere's disease.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Caloric Tests; Dose-Response Relationship, Dr | 1999 |
Middle ear instillation of gentamicin and streptomycin in chinchillas: morphologic appraisal of selective ototoxicity.
Topics: Animals; Anti-Bacterial Agents; Chinchilla; Cochlea; Disease Models, Animal; Drug Administration Rou | 1999 |
Chemical labyrinthectomy and cochlear implantation for Menière's disease--an effective treatment or a last resort?
Topics: Audiometry, Pure-Tone; Cochlear Implantation; Combined Modality Therapy; Ear, Inner; Female; Gentami | 1999 |
Presumed reduction of vestibular function in unilateral Menière's disease with aminoglycoside eardrops.
Topics: Anti-Bacterial Agents; Betamethasone; Drug Combinations; Female; Gentamicins; Glucocorticoids; Human | 1999 |
Low-dose intratympanic gentamicin treatment for dizziness in Ménière's disease.
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Dizziness; Ear, Middle; Female; Follow- | 2000 |
[Bilateral malfunction of peripheral vestibular organs. Observations of 20 cases of Dandy syndrome].
Topics: Anti-Bacterial Agents; Deafness; Dose-Response Relationship, Drug; Female; Functional Laterality; Ge | 2000 |
[Meniere's disease. The clinical effect of gentamicin treatment].
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Drainage; Ear, Middle; Female; Follow-U | 2000 |
Intratympanic therapy for Ménière's disease. High-concentration gentamicin with round-window protection.
Topics: Adult; Anti-Bacterial Agents; Ear, Middle; Female; Follow-Up Studies; Gentamicins; Hearing; Humans; | 1999 |
Round window gentamicin mu-catheter--a new therapeutic tool in Ménière's disease.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Catheterization; Equipment Design; Female; Ge | 2000 |
[Round window microcatheter administered microdose of gentamycin: an alternative in the treatment of tinnitus in patients with Menière's disease].
Topics: Audiometry, Evoked Response; Catheterization; Follow-Up Studies; Gentamicins; Humans; Infusion Pumps | 2000 |
Intratympanic gentamicin for the treatment of unilateral Meniere's disease.
Topics: Adult; Aged; Audiometry, Pure-Tone; Caloric Tests; Female; Gentamicins; Hearing Loss; Humans; Instil | 2000 |
Preliminary results of a new delivery system for gentamicin to the inner ear in patients with Meniere's disease.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Caloric Tests; Drug Administration Routes; Ea | 2000 |
Continuous intratympanic infusion of gentamicin via a microcatheter in Menière's disease.
Topics: Administration, Topical; Anti-Bacterial Agents; Auditory Threshold; Caloric Tests; Catheterization; | 2001 |
Unpredictable hearing loss after intratympanic gentamicin treatment for vertigo. A new theory.
Topics: Adult; Aged; Anti-Bacterial Agents; Deafness; Female; Gentamicins; Humans; Male; Meniere Disease; Ve | 2001 |
[Ablation therapy with gentamycin in the treatment of Meniere's disease].
Topics: Adult; Aged; Anti-Bacterial Agents; Female; Follow-Up Studies; Gentamicins; Humans; Male; Meniere Di | 2000 |
Long-term follow-up of transtympanic gentamicin for Ménière's syndrome.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Audiometry, Pure-Tone; Drug Administration Ro | 2001 |
Intratympanic therapy for Ménière's disease: effect of administration of low concentration of gentamicin.
Topics: Adolescent; Adult; Aged; Dose-Response Relationship, Drug; Drug Administration Schedule; Ear, Middle | 2001 |
Patients' subjective evaluations of quality of life related to disease-specific symptoms, sense of coherence, and treatment in Ménière's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Cross-Sectional Studies; Endolymphatic Sac; Female; Gentamicins; | 2001 |
[Variability of N in Meniere's disease].
Topics: Administration, Topical; Anti-Bacterial Agents; Gentamicins; Humans; Meniere Disease; Tympanic Membr | 2001 |
Ménière's disease in childhood.
Topics: Adolescent; Anti-Bacterial Agents; Child; Deafness; Female; Gentamicins; Hearing Tests; Humans; Meni | 2001 |
Intratympanic dexamethasone, intratympanic gentamicin, and endolymphatic sac surgery for intractable vertigo in Meniere's disease.
Topics: Administration, Topical; Decompression, Surgical; Dexamethasone; Endolymphatic Sac; Gentamicins; Hum | 2001 |
Microdose gentamicin administration via the round window microcatheter: results in patients with Meniere's disease.
Topics: Adult; Aged; Audiometry; Audiometry, Evoked Response; Catheterization; Female; Gentamicins; Humans; | 2001 |
Use of the round window microcatheter in the treatment of Meniere's disease.
Topics: Adult; Anti-Bacterial Agents; Catheters, Indwelling; Drug Delivery Systems; Female; Follow-Up Studie | 2001 |
Intratympanic gentamicin therapy for persistent vertigo after endolymphatic sac surgery.
Topics: Administration, Topical; Adult; Anti-Bacterial Agents; Audiometry, Pure-Tone; Electronystagmography; | 2002 |
Visual vestibular mismatch in patients treated with intratympanic gentamicin for Meniere's disease.
Topics: Anti-Bacterial Agents; Caloric Tests; Ear, Middle; Female; Follow-Up Studies; Gentamicins; Humans; M | 2002 |
Low-dose intratympanic gentamicin treatment of Menière's disease.
Topics: Administration, Topical; Adult; Aged; Anti-Bacterial Agents; Caloric Tests; Drug Administration Sche | 1994 |
Vascular occlusion in the endolymphatic sac in Meniere's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry; Biopsy; Calcinosis; Case-Control Studies; Combined M | 2002 |
Continuous gentamicin therapy using an IntraEAR microcatheter for Meniere's disease: a retrospective study.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Catheterization; Female; Follow-Up Studies; G | 2002 |
Changes in the angular vestibulo-ocular reflex after a single dose of intratympanic gentamicin for Ménière's disease.
Topics: Functional Laterality; Gentamicins; Humans; Injections; Meniere Disease; Reflex, Vestibulo-Ocular; T | 2002 |
[Follow-up assessment of intratympanic gentamicin therapy and Saccotomia in Menière's Disease].
Topics: Aged; Auditory Threshold; Ear, Middle; Female; Follow-Up Studies; Gentamicins; Humans; Magnetic Reso | 2002 |
Hearing loss following intratympanic instillation of gentamicin for the treatment of unilateral Meniere's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Ear, Middle; Female; Gentamicins; Hearing Loss; Humans; Incidenc | 2002 |
Vestibular nerve section in a child with intractable Menière's disease.
Topics: Anti-Bacterial Agents; Child, Preschool; Ear, Middle; Gentamicins; Hearing; Humans; Male; Meniere Di | 2002 |
[The intratympanic treatment of Menière's disease with ototoxic antibiotics. A follow-up study of 55 cases (author's transl)].
Topics: Caloric Tests; Ear, Middle; Gentamicins; Hearing Disorders; Humans; Meniere Disease; Streptomycin; V | 1977 |
10 years of experience with intratympanally applied streptomycin (gentamycin) in the therapy of Morbus Menière.
Topics: Cochlea; Deafness; Epithelium; Gentamicins; Humans; Meniere Disease; Streptomycin; Time Factors | 1978 |
Chemical labyrinthectomy: local application of gentamicin for the treatment of unilateral Menière's disease.
Topics: Adult; Aged; Female; Follow-Up Studies; Gentamicins; Hearing; Humans; Instillation, Drug; Male; Meni | 1992 |
Effects of systemic and lateral semicircular canal administration of aminoglycosides on normal and hydropic inner ears.
Topics: Animals; Gentamicins; Guinea Pigs; Hair Cells, Auditory; Meniere Disease; Semicircular Canals; Strep | 1991 |
Delayed onset of ototoxic effects of gentamicin in patients with Meniére's disease.
Topics: Adult; Audiometry, Pure-Tone; Caloric Tests; Cochlea; Electrooculography; Female; Gentamicins; Human | 1991 |
Postural stability on moving platform oscillating at high frequencies. Effect of vestibular lesion.
Topics: Adult; Gentamicins; Humans; Meniere Disease; Middle Aged; Posture; Rotation; Vestibular Diseases; Ve | 1991 |
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease.
Topics: Adult; Gentamicins; Hearing Disorders; Humans; Meniere Disease; Middle Aged; Nystagmus, Pathologic; | 1991 |
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy.
Topics: Adult; Caloric Tests; Cochlea; Dizziness; Gentamicins; Humans; Instillation, Drug; Meniere Disease; | 1991 |
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy.
Topics: Adult; Caloric Tests; Cochlea; Dizziness; Gentamicins; Humans; Instillation, Drug; Meniere Disease; | 1991 |
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy.
Topics: Adult; Caloric Tests; Cochlea; Dizziness; Gentamicins; Humans; Instillation, Drug; Meniere Disease; | 1991 |
Delayed onset of ototoxic effects of gentamicin in treatment of Menière's disease. Rationale for extremely low dose therapy.
Topics: Adult; Caloric Tests; Cochlea; Dizziness; Gentamicins; Humans; Instillation, Drug; Meniere Disease; | 1991 |
Intratympanic gentamycin in severe Ménière's disease.
Topics: Ear, Middle; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Aged; Middle Ear Ventilation | 1990 |
Inner ear effects of topical gentamicin treatment in patients with Menière's disease.
Topics: Administration, Topical; Aged; Cochlea; Female; Gentamicins; Humans; Meniere Disease; Microscopy, El | 1990 |
[Treatment of tinnitus with gentamicin].
Topics: Female; Gentamicins; Humans; Male; Meniere Disease; Middle Aged; Tinnitus | 1990 |
Gentamicin and other ototoxic antibiotics for the transtympanic treatment of Menière's disease.
Topics: Auditory Threshold; Drug Administration Schedule; Ear, Middle; Follow-Up Studies; Gentamicins; Human | 1989 |
Evaluation of a three-stage management program for Menière's disease.
Topics: Adolescent; Adult; Aged; Child; Chlorthalidone; Combined Modality Therapy; Endolymphatic Sac; Evalua | 1989 |
[Long-term results of gentamycin therapy of Menière's disease].
Topics: Adolescent; Adult; Aged; Audiometry, Pure-Tone; Auditory Threshold; Female; Follow-Up Studies; Genta | 1989 |
Middle ear ototoxic treatment for inner ear disease.
Topics: Adult; Aged; Ear, Middle; Gentamicins; Humans; Meniere Disease; Middle Aged; Time Factors | 1989 |
Intratympanic gentamycin therapy for Menière's disease placed by tubal catheter with systemic isosorbide.
Topics: Adult; Aged; Catheterization; Drug Therapy, Combination; Female; Gentamicins; Humans; Isosorbide; Ma | 1988 |
Vestibular and audiologic functions in gentamicin-treated Menière's disease.
Topics: Administration, Topical; Adult; Aged; Audiometry; Audiometry, Pure-Tone; Ear, Middle; Female; Gentam | 1988 |
Transtympanic administration of aminoglycosides in patients with Menière's disease.
Topics: Drug Administration Routes; Gentamicins; Humans; Meniere Disease; Tympanic Membrane | 1988 |
Drop attacks in Menière's disease.
Topics: Adult; Female; Gentamicins; Humans; Male; Meniere Disease; Middle Aged; Vestibule, Labyrinth | 1988 |
Intratympanic application of gentamicin for treatment of Menière's disease.
Topics: Adolescent; Adult; Aged; Child; Ear, Middle; Gentamicins; Humans; Meniere Disease; Middle Aged | 1986 |
[Effect of aminoglycosides on experimentally induced endolymphatic hydrops].
Topics: Animals; Endolymph; Female; Gentamicins; Guinea Pigs; Kanamycin; Male; Meniere Disease | 1986 |
[Technical difficulties in intratympanic gentamycin therapy in Menière disease].
Topics: Catheterization; Ear, Middle; Gentamicins; Humans; Meniere Disease | 1985 |
[Treatment of Meniere's disease: conservative or operative].
Topics: Betahistine; Diuretics; Ear, Inner; Ear, Middle; Endolymphatic Sac; Gentamicins; Humans; Meniere Dis | 1985 |
The dizzy patient.
Topics: Diazepam; Drainage; Ear; Ear Neoplasms; Ethacrynic Acid; Gentamicins; Hearing Disorders; Humans; Inf | 1972 |
Vertigo and its treatment.
Topics: Air Pressure; Anxiety; Brain Diseases; Cardiovascular Diseases; Cervical Vertebrae; Ear Diseases; Et | 1974 |
Ototoxicity of gentamicin in man: a survey and controlled analysis of clinical experience in the United States.
Topics: Adult; Age Factors; Body Weight; Ear, Inner; Gentamicins; Hearing Disorders; Humans; Kidney Diseases | 1971 |