gentamicin has been researched along with Marfan Syndrome in 2 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Marfan Syndrome: An autosomal dominant disorder of CONNECTIVE TISSUE with abnormal features in the heart, the eye, and the skeleton. Cardiovascular manifestations include MITRAL VALVE PROLAPSE, dilation of the AORTA, and aortic dissection. Other features include lens displacement (ectopia lentis), disproportioned long limbs and enlarged DURA MATER (dural ectasia). Marfan syndrome (type 1) is associated with mutations in the gene encoding FIBRILLIN-1 (FBN1), a major element of extracellular microfibrils of connective tissue. Mutations in the gene encoding TYPE II TGF-BETA RECEPTOR (TGFBR2) are associated with Marfan syndrome type 2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Standard treatment of bacterial endocarditis with penicillin and gentamicin was effective in both patients." | 1.33 | Infective endocarditis due to Abiotrophia defectiva: a report of two cases. ( Gasparac, I; Lainscak, M; Lejko-Zupanc, T; Mueller-Premru, M; Pirs, M; Strumbelj, I, 2005) |
| "The Marfan syndrome is a heritable disease with an autosomal dominant inheritance." | 1.29 | [Infectious endocarditis. A form of the presentation of Marfan's syndrome--a clinical case]. ( Capucho, R; Fernando, PM; Ferreira, A; Macedo, F, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lainscak, M | 1 |
| Lejko-Zupanc, T | 1 |
| Strumbelj, I | 1 |
| Gasparac, I | 1 |
| Mueller-Premru, M | 1 |
| Pirs, M | 1 |
| Ferreira, A | 1 |
| Fernando, PM | 1 |
| Macedo, F | 1 |
| Capucho, R | 1 |
2 other studies available for gentamicin and Marfan Syndrome
| Article | Year |
|---|---|
Infective endocarditis due to Abiotrophia defectiva: a report of two cases.
Topics: Adult; Anti-Bacterial Agents; Aortic Valve; Ceftriaxone; Drug Therapy, Combination; Endocarditis, Ba | 2005 |
[Infectious endocarditis. A form of the presentation of Marfan's syndrome--a clinical case].
Topics: Adult; Aortic Valve; Combined Modality Therapy; Drug Therapy, Combination; Endocarditis, Bacterial; | 1993 |