Page last updated: 2024-10-27

gentamicin and Liver Dysfunction

gentamicin has been researched along with Liver Dysfunction in 21 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Research Excerpts

ExcerptRelevanceReference
"MS extract can protect the kidney against toxic effects of gentamicin, and thus, the degree of harmful effects of nephrotoxicity on remote organs including the liver will be decreased."5.51Amelioration of renal and hepatic function, oxidative stress, inflammation and histopathologic damages by Malva sylvestris extract in gentamicin induced renal toxicity. ( Jassemi, SV; Madani, SH; Modarresi, M; Mohamadi Yarijani, Z; Najafi, H; Shackebaei, D, 2019)
" The results indicated that long-term VI-28 treatment invariably protected against oxidative tissue damage in the rat models of cerebral/myocardial ischemia-reperfusion injury, CCl4 hepatotoxicity, and gentamicin nephrotoxicity."3.74Long-term treatment with a Yang-invigorating Chinese herbal formula produces generalized tissue protection against oxidative damage in rats. ( Chen, N; Chiu, PY; Ko, KM; Leung, HY; Poon, MK; Siu, AH, 2008)
" Similar findings were obtained in rats with CCl4 liver damage or gentamicin nephrotoxicity, except that those rats hardly exhibited anemia because of a simultaneous occurrence of hemoconcentration."3.67The influence of single or repeated phlebotomy on the physiological condition of normal and diseased rats. ( Furuhama, K; Igarashi, K; Kato, M; Onodera, T; Suzuki, N, 1987)
"MS extract can protect the kidney against toxic effects of gentamicin, and thus, the degree of harmful effects of nephrotoxicity on remote organs including the liver will be decreased."1.51Amelioration of renal and hepatic function, oxidative stress, inflammation and histopathologic damages by Malva sylvestris extract in gentamicin induced renal toxicity. ( Jassemi, SV; Madani, SH; Modarresi, M; Mohamadi Yarijani, Z; Najafi, H; Shackebaei, D, 2019)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-199010 (47.62)18.7374
1990's2 (9.52)18.2507
2000's2 (9.52)29.6817
2010's7 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yang, Q1
Wu, Z1
Liu, F1
Wang, J1
Ma, W1
Hu, H1
Li, F1
Pan, Q1
Mohamadi Yarijani, Z1
Najafi, H1
Shackebaei, D1
Madani, SH1
Modarresi, M1
Jassemi, SV1
Buchanan, R1
Stoesser, N1
Crook, D1
Bowler, IC1
Li, YT1
Wang, L1
Chen, Y1
Chen, YB1
Wang, HY1
Wu, ZW1
Li, LJ1
Günşar, C1
Vatansever, S1
Var, A1
Aygören, R1
Yilmaz, O1
Türköz, E1
Sencan, A1
Mir, E1
Tan, L1
Narayan, SB1
Chen, J1
Meyers, GD1
Bennett, MJ1
Khan, MR1
Badar, I1
Siddiquah, A1
Ackerman, Z1
Karmeli, F1
Pizov, G1
Ben-Dov, I1
Pappo, O1
Chiu, PY1
Leung, HY1
Siu, AH1
Chen, N1
Poon, MK1
Ko, KM1
Baer, DM1
Jones, RN1
Mullooly, JP1
Horner, W1
Abidin, Z1
Iyngkaran, N1
Puthucheary, SD1
Whiting, PH1
Simpson, JG1
Davidson, RJ1
Thomson, AW1
Noone, P1
Abeysundere, RL1
Bradley, JM1
de Lemos, E1
Pariat, C1
Piriou, A1
Fauconneau, B1
Courtois, P1
Lichtman, SN1
Keku, J1
Schwab, JH1
Sartor, RB1
Kassirer, JP1
Kopelman, RI1
Furuhama, K1
Kato, M1
Suzuki, N1
Igarashi, K1
Onodera, T1
Stillman, AE1
Earnest, DL1
Woolfenden, JM1
Ventura, E1
Zeneroli, ML1
von Oldershausen, HF1
Held, H1
Menz, HP1
Schmidinger, H1
Truchot, MR1

Other Studies

21 other studies available for gentamicin and Liver Dysfunction

ArticleYear
Effective Treatment of Chronic Proliferative Cholangitis by Local Gentamicin Infusion in Rabbits.
    BioMed research international, 2018, Volume: 2018

    Topics: Animals; Anti-Bacterial Agents; Asia, Eastern; Bile Ducts; Bile Ducts, Intrahepatic; Cholangitis; Di

2018
Amelioration of renal and hepatic function, oxidative stress, inflammation and histopathologic damages by Malva sylvestris extract in gentamicin induced renal toxicity.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 112

    Topics: Animals; Dose-Response Relationship, Drug; Gentamicins; Inflammation; Kidney; Kidney Diseases; Kidne

2019
Multidrug-resistant Escherichia coli soft tissue infection investigated with bacterial whole genome sequencing.
    BMJ case reports, 2014, Oct-19, Volume: 2014

    Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; beta-Lactams; Ciprofloxacin; D

2014
Effects of gut microflora on hepatic damage after acute liver injury in rats.
    The Journal of trauma, 2010, Volume: 68, Issue:1

    Topics: Animals; Bacterial Translocation; Chemical and Drug Induced Liver Injury; Cytokines; Endotoxins; Esc

2010
Antibiotic treatment is superior to ursodeoxycholic acid on total parenteral nutrition associated hepatic dysfunction.
    Pediatric surgery international, 2010, Volume: 26, Issue:5

    Topics: Analysis of Variance; Animals; Apoptosis; bcl-2-Associated X Protein; Bilirubin; Caspase 3; Fas Liga

2010
PTC124 improves readthrough and increases enzymatic activity of the CPT1A R160X nonsense mutation.
    Journal of inherited metabolic disease, 2011, Volume: 34, Issue:2

    Topics: Carnitine O-Palmitoyltransferase; Child, Preschool; Codon; Codon, Nonsense; Fatty Acids; Female; Fib

2011
Prevention of hepatorenal toxicity with Sonchus asper in gentamicin treated rats.
    BMC complementary and alternative medicine, 2011, Nov-15, Volume: 11

    Topics: Animals; Anti-Bacterial Agents; Gentamicins; Humans; Kidney; Kidney Diseases; Liver; Liver Diseases;

2011
Renal effects of gentamicin in chronic bile duct ligated rats.
    Digestive diseases and sciences, 2006, Volume: 51, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Bile Ducts; Cholestasis; Dinoprostone; Disease Models, Animal; Dose-

2006
Long-term treatment with a Yang-invigorating Chinese herbal formula produces generalized tissue protection against oxidative damage in rats.
    Rejuvenation research, 2008, Volume: 11, Issue:1

    Topics: Animals; Carbon Tetrachloride; Carnosine; Chemical and Drug Induced Liver Injury; Cholecalciferol; C

2008
Protocol for the study of drug interferences in laboratory tests: cefotaxime interference in 24 clinical tests.
    Clinical chemistry, 1983, Volume: 29, Issue:10

    Topics: Blood Chemical Analysis; Cefotaxime; False Positive Reactions; Female; Gentamicins; Heart Diseases;

1983
Fulminant hepatic failure and shigella bacteremia.
    The Medical journal of Malaysia, 1983, Volume: 38, Issue:2

    Topics: Child, Preschool; Dysentery, Bacillary; Gentamicins; Humans; Liver Diseases; Male; Sepsis; Shigella

1983
The toxic effects of combined administration of cyclosporin A and gentamicin.
    British journal of experimental pathology, 1982, Volume: 63, Issue:5

    Topics: Acetylglucosaminidase; Animals; Aspartate Aminotransferases; Blood Proteins; Bone Marrow; Chemical a

1982
Bacteraemia.
    The Journal of antimicrobial chemotherapy, 1978, Volume: 4 Suppl C

    Topics: Adult; Anti-Bacterial Agents; Digestive System Surgical Procedures; Female; Gentamicins; Humans; Liv

1978
[Circadian variations in the nephrotoxicity of the vancomycin-gentamicin combination in rats].
    Pathologie-biologie, 1991, Volume: 39, Issue:1

    Topics: Acetylglucosaminidase; Aminopeptidases; Animals; CD13 Antigens; Chemical and Drug Induced Liver Inju

1991
Hepatic injury associated with small bowel bacterial overgrowth in rats is prevented by metronidazole and tetracycline.
    Gastroenterology, 1991, Volume: 100, Issue:2

    Topics: Animals; Bacteria; Bacterial Infections; Colony Count, Microbial; Female; Gentamicins; Hepatomegaly;

1991
A picture is worth a thousand words.
    Hospital practice (Office ed.), 1986, Jul-15, Volume: 21, Issue:7

    Topics: Gentamicins; Humans; Hypotension; Kidney Diseases; Liver Diseases; Male; Middle Aged; Physical Exami

1986
The influence of single or repeated phlebotomy on the physiological condition of normal and diseased rats.
    The Journal of toxicological sciences, 1987, Volume: 12, Issue:1

    Topics: Anemia; Animals; Blood Cell Count; Blood Pressure; Bloodletting; Carbon Tetrachloride; Chemical and

1987
Hepatobiliary scintigraphy for cholestasis in congenital hepatic fibrosis. Diagnosis and treatment.
    American journal of diseases of children (1960), 1985, Volume: 139, Issue:1

    Topics: Bile Ducts, Intrahepatic; Child; Cholangitis; Cholestasis; Dehydrocholic Acid; Gentamicins; Humans;

1985
[Gentamicin and hepatobiliary infections].
    Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1973, Apr-17, Volume: 62, Issue:16

    Topics: Aged; Bacterial Infections; Cholangitis; Female; Gallbladder Diseases; Gentamicins; Humans; Liver Di

1973
[Antimicrobial chemotherapy in liver and kidney lesions].
    Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1971, Volume: 77

    Topics: Aminosalicylic Acids; Anti-Infective Agents; Creatinine; Gentamicins; Humans; Kidney Failure, Chroni

1971
[Injectable gentamicin in hepato-biliary and digestive pathology].
    Journal de medecine de Lyon, 1968, Mar-20, Volume: 49, Issue:139

    Topics: Biliary Tract Diseases; Colitis; Diverticulitis, Colonic; Gentamicins; Humans; Liver Diseases

1968