Page last updated: 2024-10-27

gentamicin and Lipidoses

gentamicin has been researched along with Lipidoses in 9 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Lipidoses: Conditions characterized by abnormal lipid deposition due to disturbance in lipid metabolism, such as hereditary diseases involving lysosomal enzymes required for lipid breakdown. They are classified either by the enzyme defect or by the type of lipid involved.

Research Excerpts

ExcerptRelevanceReference
"Rats treated with gentamicin also had increased urinary levels of several phosphatidylinositol (PI), phosphatidylcholine (PC), and phosphatidylethanolamine (PE) species."1.34Biomarkers to monitor drug-induced phospholipidosis. ( Alden, C; Baronas, ET; Hsieh, FY; Lee, JW, 2007)
"In addition to the phospholipidosis in utero, drug exposure results in toxicity to the offspring; newborn rats die within 48 h of birth."1.27Newborn response to cationic amphiphilic drugs. ( Kacew, S; Reasor, MJ, 1985)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19906 (66.67)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baronas, ET1
Lee, JW1
Alden, C1
Hsieh, FY1
D'Amico, DJ2
Kenyon, KR2
Feldman, S1
Wang, MY1
Kaloyanides, GJ1
Samadian, T1
Dehpour, AR1
Amini, S1
Nouhnejad, P1
Guo, Y1
Jiang, S1
Yang, W1
Kacew, S3
Reasor, MJ1
Tabatabay, CA1
Hanninen, LA1

Other Studies

9 other studies available for gentamicin and Lipidoses

ArticleYear
Biomarkers to monitor drug-induced phospholipidosis.
    Toxicology and applied pharmacology, 2007, Jan-01, Volume: 218, Issue:1

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Azithromycin; Biomarkers; Chroma

2007
Drug-induced lipidoses of the cornea and conjunctiva.
    International ophthalmology, 1981, Volume: 4, Issue:1-2

    Topics: Amiodarone; Amodiaquine; Chloroquine; Conjunctival Diseases; Corneal Diseases; Fabry Disease; Female

1981
Aminoglycosides induce a phospholipidosis in the renal cortex of the rat: an early manifestation of nephrotoxicity.
    The Journal of pharmacology and experimental therapeutics, 1982, Volume: 220, Issue:3

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Gentamicins; Kidney Cortex; Kidney Diseases; Lipido

1982
Inhibition of gentamicin-induced nephrotoxicity by lithium in rat.
    Histology and histopathology, 1993, Volume: 8, Issue:1

    Topics: Animals; Gentamicins; Kidney; Kidney Diseases; Kidney Tubules; Lipidoses; Lithium; Lysosomes; Male;

1993
[Experimental observation of antagonism of polyaspartic acid against gentamicin-induced phospholipidosis in cochlea of guinea pig].
    Zhonghua yi xue za zhi, 2001, Aug-10, Volume: 81, Issue:15

    Topics: Animals; Aspartic Acid; Chromatography, High Pressure Liquid; Cochlea; Cochlear Diseases; Gentamicin

2001
Newborn response to cationic amphiphilic drugs.
    Federation proceedings, 1985, Volume: 44, Issue:7

    Topics: Animals; Animals, Newborn; Chlorphentermine; Dexamethasone; Drug Interactions; Female; Fetus; Gentam

1985
Cationic amphiphilic drug-induced renal cortical lysosomal phospholipidosis: an in vivo comparative study with gentamicin and chlorphentermine.
    Toxicology and applied pharmacology, 1987, Volume: 91, Issue:3

    Topics: Animals; Chlorphentermine; Gentamicins; Kidney Cortex; Lipidoses; Lysosomes; Male; Phentermine; Phos

1987
Experimental drusen formation induced by intravitreal aminoglycoside injection.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1987, Volume: 105, Issue:6

    Topics: Amikacin; Aminoglycosides; Animals; Fluorescein Angiography; Gentamicins; Lipidoses; Microscopy, Ele

1987
Gentamicin or chlorphentermine induction of phospholipidosis in the developing organism: role of tissue and species in manifestation of toxicity.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 232, Issue:1

    Topics: Animals; Animals, Newborn; Chlorphentermine; Female; Gentamicins; Kidney; Lipidoses; Liver; Lung; Ph

1985