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gentamicin and Leukocytopenia

gentamicin has been researched along with Leukocytopenia in 23 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Research Excerpts

ExcerptRelevanceReference
"An experimental Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats was used to study the impact of the duration of infection on the bactericidal activity of ceftazidime, gentamicin and ciprofloxacin."7.68Impact of the duration of infection on the activity of ceftazidime, gentamicin and ciprofloxacin in Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats. ( Bakker-Woudenberg, IA; Michel, MF; Roosendaal, R; van den Berghe-van Raffe, M; Vink-van den Berg, JC, 1991)
"The impact of the dosage schedule on the therapeutic efficacy of antibiotics was investigated in experimental Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats."5.28Impact of the dosage schedule on the efficacy of ceftazidime, gentamicin and ciprofloxacin in Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats. ( Bakker-Woudenberg, IA; Michel, BM; Roosendaal, R; van den Berghe-van Raffe, M; Vink-van den Berg, JC, 1989)
"To determine: (1) whether a lumbar puncture (LP) is indicated in asymptomatic full-term newborns delivered by mothers at risk of intrapartum sepsis; and (2) whether gentamicin improves bacterial coverage for such newborns when used with ampicillin."3.69Term newborns who are at risk for sepsis: are lumbar punctures necessary? ( Johnson, CE; Pethe, K; Saxena, K; Super, DM; Whitwell, JK, 1997)
"An experimental Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats was used to study the impact of the duration of infection on the bactericidal activity of ceftazidime, gentamicin and ciprofloxacin."3.68Impact of the duration of infection on the activity of ceftazidime, gentamicin and ciprofloxacin in Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats. ( Bakker-Woudenberg, IA; Michel, MF; Roosendaal, R; van den Berghe-van Raffe, M; Vink-van den Berg, JC, 1991)
"Leukopenia was found in 51% of children and anaemia in 24%."1.30Brucellosis in children in south Jordan. ( Issa, H; Jamal, M, 1999)
"Treatment of disseminated Pseudomonas aeruginosa infection in leukopenic mice was evaluated using cefpirome alone and in combination with gentamicin and/or rifampin."1.28Comparative therapy with cefpirome alone and in combination with rifampin and/or gentamicin against a disseminated Pseudomonas aeruginosa infection in leukopenic mice. ( Baltch, AL; Franke, M; Michelsen, P; Ritz, WJ; Singh, J; Smith, RP; Valdes, JM; Williams, S, 1990)
"The impact of the dosage schedule on the therapeutic efficacy of antibiotics was investigated in experimental Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats."1.28Impact of the dosage schedule on the efficacy of ceftazidime, gentamicin and ciprofloxacin in Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats. ( Bakker-Woudenberg, IA; Michel, BM; Roosendaal, R; van den Berghe-van Raffe, M; Vink-van den Berg, JC, 1989)
"Gentamicin alone was not significantly better than no specific therapy."1.26Experimental Pseudomonas pneumonia in leukopenic dogs: comparison of therapy with antibiotics and granulocyte transfusions. ( Dale, DC; Elin, RJ; Herzig, GP; Pennington, JE; Reynolds, HY, 1976)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-199016 (69.57)18.7374
1990's4 (17.39)18.2507
2000's3 (13.04)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Günther, I1
Bohnenstengel, C1
Kaben, U1
Konrad, H1
Jäger, E1
Anders, O1
Angehrn, P1
Cryz, SJ1
Fürer, E1
Germanier, R1
Gerber, AU2
Vastola, AP1
Brandel, J1
Craig, WA2
Johnson, CE1
Whitwell, JK1
Pethe, K1
Saxena, K1
Super, DM1
Sachs, B1
Erdmann, S1
Borchardt, I1
Drüke, P1
Merk, HF1
Issa, H1
Jamal, M1
Alter, P1
Schaefer, JR1
Maisch, B1
Schiffelers, RM1
Storm, G1
ten Kate, MT1
Bakker-Woudenberg, IA3
Kazmierowski, JA1
Reynolds, HY3
Kauffman, JC1
Durbin, WA1
Graw, RG2
Devlin, HB1
Lau, WK1
Young, LS1
Black, RE1
Winston, DJ1
Linne, SR1
Weinstein, RJ1
Hewitt, WL1
Dale, DC2
Pennington, JE2
Elin, RJ2
Herzig, GP1
Gleckman, R1
Roosendaal, R2
van den Berghe-van Raffe, M2
Vink-van den Berg, JC2
Michel, MF1
Valdes, JM1
Baltch, AL1
Smith, RP1
Franke, M1
Ritz, WJ1
Williams, S1
Michelsen, P1
Singh, J1
Michel, BM1
Hansen, SW1
Friis, H1
Ernst, P1
Vejlsgaard, R1
Hansen, HH1
Arai, S1
Pitts, TW1
Corrigan, JJ1
Bell, BM1
VanOmmen, RA1
Klastersky, J1
Daneau, D1
Henri, A1
Cappel, R1
Hensgens, C1

Trials

2 trials available for gentamicin and Leukocytopenia

ArticleYear
Comparative efficacy and toxicity of amikacin/carbenicillin versus gentamicin/carbenicillin in leukopenic patients: a randomized prospective trail.
    The American journal of medicine, 1977, Volume: 62, Issue:6

    Topics: Adult; Amikacin; Bacterial Infections; Carbenicillin; Drug Synergism; Gentamicins; Hearing Disorders

1977
Latamoxef versus carbenicillin plus gentamicin or carbenicillin plus mecillinam in leukopenic, febrile patients with solid tumors.
    Acta medica Scandinavica, 1986, Volume: 220, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Carbenicillin; Cisplatin; Clinical Trials as Topic; Female; Feve

1986

Other Studies

21 other studies available for gentamicin and Leukocytopenia

ArticleYear
[Results of prevention of infection with selective decontamination of the digestive tract in the treatment of leukemia].
    Folia haematologica (Leipzig, Germany : 1928), 1984, Volume: 111, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Aged; Ampicillin; Bacterial Infections; Cephalothin; Digestive Sys

1984
In vitro and in vivo synergy between ceftriaxone and aminoglycosides against Pseudomonas aeruginosa.
    European journal of clinical microbiology, 1983, Volume: 2, Issue:5

    Topics: Amikacin; Animals; Cefotaxime; Ceftriaxone; Dose-Response Relationship, Drug; Drug Synergism; Drug T

1983
Passive protection against Pseudomonas aeruginosa infection in an experimental leukopenic mouse model.
    Infection and immunity, 1983, Volume: 40, Issue:2

    Topics: Animals; Antibodies, Bacterial; Antibody Specificity; Bacterial Toxins; Disease Models, Animal; Gent

1983
Selection of aminoglycoside-resistant variants of Pseudomonas aeruginosa in an in vivo model.
    The Journal of infectious diseases, 1982, Volume: 146, Issue:5

    Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Drug Synergism; Female; Gentamicins; Kinetics; Leuk

1982
Aminoglycoside-selected subpopulations of Pseudomonas aeruginosa: characterization and virulence in normal and leukopenic mice.
    The Journal of laboratory and clinical medicine, 1982, Volume: 100, Issue:5

    Topics: Agranulocytosis; Aminoglycosides; Animals; Anti-Bacterial Agents; Drug Resistance, Microbial; Female

1982
Term newborns who are at risk for sepsis: are lumbar punctures necessary?
    Pediatrics, 1997, Volume: 99, Issue:4

    Topics: Ampicillin; Bacteremia; Drug Therapy, Combination; Gentamicins; Humans; Infant, Newborn; Leukocyte C

1997
Drug-induced allergic cytopenia: in vitro confirmation by the lymphocyte transformation test.
    Archives of internal medicine, 2000, Jul-24, Volume: 160, Issue:14

    Topics: Adult; Ampicillin; Diagnosis, Differential; Drug Hypersensitivity; Drug Therapy, Combination; Endoca

2000
Brucellosis in children in south Jordan.
    Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit, 1999, Volume: 5, Issue:5

    Topics: Adolescent; Anemia; Animals; Anti-Bacterial Agents; Arthralgia; Brucellosis; Child; Child, Preschool

1999
[Impediment of cellular immune response under treatment with ticlopidine in a patient with Staphylococcus aureus endocarditis].
    Zeitschrift fur Kardiologie, 2000, Volume: 89, Issue:8

    Topics: Agranulocytosis; Angioplasty, Balloon, Coronary; Anti-Bacterial Agents; Clarithromycin; Coronary Dis

2000
Therapeutic efficacy of liposome-encapsulated gentamicin in rat Klebsiella pneumoniae pneumonia in relation to impaired host defense and low bacterial susceptibility to gentamicin.
    Antimicrobial agents and chemotherapy, 2001, Volume: 45, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Colony Count, Microbial; Drug Carriers; Female; Gentamicins; Klebsie

2001
Experimental pneumonia due to Pseudomonas aeruginosa in leukopenic dogs: prolongation of survival by combined treatment with passive antibody to Pseudomonas and granulocyte transfusions.
    The Journal of infectious diseases, 1977, Volume: 135, Issue:3

    Topics: Animals; Antibodies, Bacterial; Blood Transfusion; Disease Models, Animal; Dogs; Gentamicins; Granul

1977
Experimental Pseudomonas pneumonia in leukopenic dogs: comparison of therapy with antibiotics and granulocyte transfusions.
    Blood, 1976, Volume: 47, Issue:5

    Topics: Animals; Blood Transfusion; Carbenicillin; Dogs; Gentamicins; Granulocytes; Leukocytes; Leukopenia;

1976
Amikacin.
    American family physician, 1976, Volume: 14, Issue:6

    Topics: Amikacin; Bacterial Infections; Drug Resistance, Microbial; Gentamicins; Gram-Negative Aerobic Bacte

1976
Impact of the duration of infection on the activity of ceftazidime, gentamicin and ciprofloxacin in Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1991, Volume: 10, Issue:12

    Topics: Animals; Bacteremia; Ceftazidime; Ciprofloxacin; Disease Models, Animal; Drug Administration Schedul

1991
Comparative therapy with cefpirome alone and in combination with rifampin and/or gentamicin against a disseminated Pseudomonas aeruginosa infection in leukopenic mice.
    The Journal of infectious diseases, 1990, Volume: 162, Issue:5

    Topics: Animals; Cefpirome; Cephalosporins; Drug Therapy, Combination; Gentamicins; Kidney; Leukopenia; Live

1990
Impact of the dosage schedule on the efficacy of ceftazidime, gentamicin and ciprofloxacin in Klebsiella pneumoniae pneumonia and septicemia in leukopenic rats.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1989, Volume: 8, Issue:10

    Topics: Animals; Anti-Bacterial Agents; Ceftazidime; Ciprofloxacin; Drug Administration Schedule; Female; Ge

1989
[Improved detection of significant pathogens in blood culture].
    Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases, 1985, Volume: 59, Issue:3

    Topics: Bacteriological Techniques; Blood; Child; Drug Resistance, Microbial; Escherichia coli; Gentamicins;

1985
Granulocyte transfusion therapy of experimental Pseudomonas pneumonia.
    The Journal of clinical investigation, 1974, Volume: 54, Issue:3

    Topics: Animals; Blood Platelets; Blood Transfusion; Disease Models, Animal; Dogs; Gentamicins; Leukocyte Co

1974
Comparison between the polymyxins and gentamicin in preventing endotoxin-induced intravascular coagulation and leukopenia.
    Infection and immunity, 1971, Volume: 4, Issue:5

    Topics: Animals; Colistin; Disseminated Intravascular Coagulation; Endotoxins; Escherichia coli; Gentamicins

1971
Untoward effects of antimicrobial agents on major organ systems.
    The Medical clinics of North America, 1974, Volume: 58, Issue:3

    Topics: Agranulocytosis; Amphotericin B; Anemia, Aplastic; Anemia, Hemolytic; Anti-Bacterial Agents; Ataxia;

1974
Antibiotic combinations of gram-negative infections in patients with cancer.
    European journal of cancer, 1973, Volume: 9, Issue:6

    Topics: Ampicillin; Bacteria; Bacterial Infections; Carbenicillin; Cephalothin; Drug Therapy, Combination; E

1973