gentamicin has been researched along with Kidney Diseases in 643 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A multicenter comparative study was carried out to evaluate the efficacy of aztreonam and gentamicin in 186 patients with symptomatic renal or urinary tract infections." | 9.06 | Multicenter comparative study of aztreonam and gentamicin in the treatment of renal and urinary tract infections. ( Albertazzi, A; Bonadio, M; Fusaroli, M; Lotti, T; Miano, L; Salvia, G; Sasdelli, M; Ventriglia, L; Villa, G; Zucchelli, P, 1989) |
| " This paper reports the results of studies concerning carnosine's role in kidney diseases, particularly in ischemia/reperfusion induced acute renal failure, diabetic nephropathy, gentamicin-induced nephrotoxicity and also in blood pressure regulation." | 8.88 | [Carnosine, carnosinase and kidney diseases]. ( Kiliś-Pstrusińska, K, 2012) |
| "Gentamicin is widely used in the treatment of suspected or proven neonatal sepsis." | 8.83 | One dose per day compared to multiple doses per day of gentamicin for treatment of suspected or proven sepsis in neonates. ( Ahmed, M; Hagan, R; Rao, SC, 2006) |
| " This study was aimed at evaluating the effect of rutin on oxidative stress, inflammation, apoptosis, and autophagy in gentamicin-induced nephrotoxicity in rats." | 7.81 | Rutin attenuates gentamicin-induced renal damage by reducing oxidative stress, inflammation, apoptosis, and autophagy in rats. ( Aktas, E; Benzer, F; Hanedan, B; Kandemir, FM; Kilic, K; Kirbas, A; Ozkaraca, M; Yildirim, BA, 2015) |
| "This study investigates the possible renoprotective effect of GSE against oxidative stress, renal impairment, and hypercholesterolemia (HC) induced by gentamicin (GM) and cholesterol-enriched diet." | 7.77 | Renoprotective effect of grape seed extract against oxidative stress induced by gentamicin and hypercholesterolemia in rats. ( Salem, EA; Salem, NA, 2011) |
| "Of 163 patients with intertrochanteric hip fractures 87 received 2 g dicloxacillin and 240 mg of gentamicin preoperatively, and 76 patients had no antibiotic prophylaxis." | 7.70 | Nephrotoxicity by dicloxacillin and gentamicin in 163 patients with intertrochanteric hip fractures. ( Due Olsen, S; Mafi, M; Solgaard, L; Toftgaard Jensen, T; Tuxoe, JI, 2000) |
| "29 patients with serious renal or urinary tract infections were treated with netilmicin (initial dose 1." | 7.66 | Netilmicin therapy of serious renal and urinary tract infections in patients with normal and impaired renal function. ( Denneberg, T; Haeger, K; Juhlin, I, 1980) |
| "Gentamicin is an aminoglycoside antibiotic commonly administrated to patients with Gram-negative infections." | 5.56 | Toll-like receptor-2 mediates systemic inflammation in gentamicin-induced rat nephrotoxicity. ( Janfeshan, S; Karimi, Z; Pakfetrat, Z; Roozbeh, J, 2020) |
| "MS extract can protect the kidney against toxic effects of gentamicin, and thus, the degree of harmful effects of nephrotoxicity on remote organs including the liver will be decreased." | 5.51 | Amelioration of renal and hepatic function, oxidative stress, inflammation and histopathologic damages by Malva sylvestris extract in gentamicin induced renal toxicity. ( Jassemi, SV; Madani, SH; Modarresi, M; Mohamadi Yarijani, Z; Najafi, H; Shackebaei, D, 2019) |
| "Tobramycin is a new aminoglycoside antibiotic with pharmacological similarities to gentamicin." | 5.26 | Tobramycin in the treatment of severe and complicated urinary tract infections. ( Bailey, RR; Peddie, B, 1976) |
| "Extensive necrosis was evident in the proximal tubes in each fish injected with gentamicin at every time period, regardless of route of administration." | 5.08 | Evaluation of gentamicin-induced nephrotoxicosis in toadfish. ( Chamie, SJ; Kinnel, M; Reimschuessel, R, 1996) |
| "A multicenter comparative study was carried out to evaluate the efficacy of aztreonam and gentamicin in 186 patients with symptomatic renal or urinary tract infections." | 5.06 | Multicenter comparative study of aztreonam and gentamicin in the treatment of renal and urinary tract infections. ( Albertazzi, A; Bonadio, M; Fusaroli, M; Lotti, T; Miano, L; Salvia, G; Sasdelli, M; Ventriglia, L; Villa, G; Zucchelli, P, 1989) |
| "During a 7 month trial for therapy of polymicrobial surgical sepsis, intravenous antibiotic treatment was randomized between gentamicin (1 mg/kg every 8 hours) plus clindamycin (8 mg/kg every 6 hours), and the cephalosporin, ceftriaxone (1 g every 12 hours) in 197 patients, of whom 99 were being treated for peritonitis, 93 for soft tissue sepsis, and 5 for other forms of infection." | 5.05 | Ceftriaxone versus combined gentamicin and clindamycin for polymicrobial surgical sepsis. ( Bourneuf, AA; Geheber, CE; Mullins, RJ; Stone, HH; Strom, PR, 1984) |
| "The efficacy and tolerance of netilmicin was studied in 28 elderly male patients with varying degrees of renal function impairment who suffered from complicated urinary tract infections." | 5.04 | Netilmicin treatment of complicated urinary tract infection in patients with renal function impairment. ( Frimodt-Möller, N; Madsen, PO; Maigaard, S, 1979) |
| " This paper reports the results of studies concerning carnosine's role in kidney diseases, particularly in ischemia/reperfusion induced acute renal failure, diabetic nephropathy, gentamicin-induced nephrotoxicity and also in blood pressure regulation." | 4.88 | [Carnosine, carnosinase and kidney diseases]. ( Kiliś-Pstrusińska, K, 2012) |
| "Gentamicin is widely used in the treatment of suspected or proven neonatal sepsis." | 4.83 | One dose per day compared to multiple doses per day of gentamicin for treatment of suspected or proven sepsis in neonates. ( Ahmed, M; Hagan, R; Rao, SC, 2006) |
| " Potassium dichromate and gentamicin nephrotoxicity assessed in terms of body weight, kidney weight, creatinine, urea, uric acid, BUN, albumin and total protein." | 3.88 | Potential action of Rumex vesicarius (L.) against potassium dichromate and gentamicin induced nephrotoxicity in experimental rats. ( Bag, A; Chandiran, S; Manavalan, G; Shaik, S; Subramaniyan, V, 2018) |
| " This study was aimed at evaluating the effect of rutin on oxidative stress, inflammation, apoptosis, and autophagy in gentamicin-induced nephrotoxicity in rats." | 3.81 | Rutin attenuates gentamicin-induced renal damage by reducing oxidative stress, inflammation, apoptosis, and autophagy in rats. ( Aktas, E; Benzer, F; Hanedan, B; Kandemir, FM; Kilic, K; Kirbas, A; Ozkaraca, M; Yildirim, BA, 2015) |
| "Assessing the vulnerability of the SK with urinary tract infections (UTI) to gentamicin by means of urinary biomarkers (N-acetyl-beta-D-glucosaminidase (NAG) and urinary alpha-1-microglobulin), as well as glomerular filtration rate (GFR)." | 3.80 | Urinary biomarkers in assessing the nephrotoxic potential of gentamicin in solitary kidney patients after 7 days of therapy. ( Bob, F; Bozdog, G; Gadalean, F; Gluhovschi, C; Gluhovschi, G; Kaycsa, A; Petrica, L; Velciov, S, 2014) |
| "Gentamicin significantly increased serum creatinine, malondialdehyde, and tubular necrosis, and decreased creatinine clearance, volume density of the proximal convoluted tubules, renal glutathione, glutathione peroxidase, catalase, and superoxide dismutase compared with the control group." | 3.78 | Inhibitory effect of olive leaf extract on gentamicin-induced nephrotoxicity in rats. ( Ahmadvand, H; Tavafi, M; Toolabi, P, 2012) |
| " The aim of this study was to determine effects of inhibiting hydrogen sulphide biosynthesis by DL-propargyl glycine (an irreversible inhibitor of cystathionine gamma-lyase) on inflammation, necrosis and renal function, following treatment with gentamicin in rats." | 3.78 | Inhibition of cystathionine gamma-lyase and the biosynthesis of endogenous hydrogen sulphide ameliorates gentamicin-induced nephrotoxicity. ( Dam, VP; Kinobe, RT; Ross, A; Scott, JL, 2012) |
| " Overall, the proportion of patients reporting any adverse event was comparable between the isepamicin (13%) and amikacin (11%) groups." | 3.78 | An overview of the safety of isepamicin in adults. ( Blum, D, 1995) |
| "This study investigates the possible renoprotective effect of GSE against oxidative stress, renal impairment, and hypercholesterolemia (HC) induced by gentamicin (GM) and cholesterol-enriched diet." | 3.77 | Renoprotective effect of grape seed extract against oxidative stress induced by gentamicin and hypercholesterolemia in rats. ( Salem, EA; Salem, NA, 2011) |
| " We investigated whether paricalcitol ameliorates tubular dysfunction and fibrosis in gentamicin (GM)-induced renal injury." | 3.76 | Renoprotective effects of paricalcitol on gentamicin-induced kidney injury in rats. ( Bae, EH; Choi, C; Kim, IJ; Kim, SW; Lee, J; Ma, SK; Park, JW, 2010) |
| " The results indicated that long-term VI-28 treatment invariably protected against oxidative tissue damage in the rat models of cerebral/myocardial ischemia-reperfusion injury, CCl4 hepatotoxicity, and gentamicin nephrotoxicity." | 3.74 | Long-term treatment with a Yang-invigorating Chinese herbal formula produces generalized tissue protection against oxidative damage in rats. ( Chen, N; Chiu, PY; Ko, KM; Leung, HY; Poon, MK; Siu, AH, 2008) |
| " In rats treated with gentamicin (70 mg/Kg body weight, subcutaneously, every 12 h, for 4 days), renal oxidative stress was made evident by the increase in protein carbonyl content and 4-hydroxy-2-nonenal, and the nitrosative stress was made evident by the increase in 3-nitrotyrosine." | 3.72 | S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentamicin-induced oxidative and nitrosative stress and renal damage in vivo. ( Barrera, D; Castro, L; Chirino, YI; Hernández-Pando, R; Macías-Ruvalcaba, NA; Maldonado, PD; Medina-Campos, ON; Pedraza-Chaverrí, J; Salcedo, MI, 2004) |
| " Gentamicin (GE) acts mainly in proximal tubular cells, where it is uptake via organic anion transport system and it induces a high incidence of nephrotoxicity, which is characterized by tubular necrosis [5] leading to acute renal failure in 10 to 50% of patients." | 3.71 | Effects of gentamicin, lipopolysaccharide, and contrast media on immortalized proximal tubular cells. ( Cunha, MA; Schor, N, 2002) |
| "To determine the safety of single daily dose (SDD) gentamicin in recipients of stem cell transplantation (SCT), we evaluated all adult patients at MD Anderson Cancer Center who received SDD gentamicin for treatment of febrile neutropenia." | 3.70 | Toxicity of single daily dose gentamicin in stem cell transplantation. ( Bruton, J; Champlin, R; Ippoliti, C; Van Besien, K; Warkentin, D, 1999) |
| "Of 163 patients with intertrochanteric hip fractures 87 received 2 g dicloxacillin and 240 mg of gentamicin preoperatively, and 76 patients had no antibiotic prophylaxis." | 3.70 | Nephrotoxicity by dicloxacillin and gentamicin in 163 patients with intertrochanteric hip fractures. ( Due Olsen, S; Mafi, M; Solgaard, L; Toftgaard Jensen, T; Tuxoe, JI, 2000) |
| " Gentamicin (80 mg/kg/day intramuscularly for 6 days) produced the typical pattern of nephrotoxicity as shown by increases in serum creatinine and urea concentrations, and urinary N-acetyl-beta-D-glucosaminidase (NAG) activity and proximal renal tubular necrosis." | 3.69 | Effect of fish oil treatment on gentamicin nephrotoxicity in rats. ( Ali, BH; Bashir, AA, 1994) |
| "Clinicopathologic and renal histopathologic changes induced by gentamicin (10 mg/kg of body weight, IM, q 8 h, for 8 days) were compared in dogs fed an n-3 fatty acid-supplemented diet containing a fatty acid ratio of 5." | 3.69 | Effects of dietary n-3 fatty acid supplementation versus thromboxane synthetase inhibition on gentamicin-induced nephrotoxicosis in healthy male dogs. ( Behrend, EN; Fettman, MJ; Getzy, DM; Grauer, GF; Greco, DS; Mani, I; Reinhart, GA, 1996) |
| "The nephrotoxicity of gentamicin and amikacin was compared during presumed sepsis in 107 premature neonates." | 3.67 | Aminoglycoside-related nephrotoxicity in the premature newborn. ( Good, F; Harding, E; Klein, J; MacLeod, S; Perlman, M; Prober, CG; Rajchgot, P; Soldin, S, 1984) |
| " Six patients had acute tubular necrosis, due to rhabdomyolysis in 5 and to prolonged gentamicin therapy for bacterial endocarditis in 1." | 3.67 | [Renal disease associated with heroin abuse]. ( Beaufils, H; Chauveau, P; Mougenot, B; Pourriat, JL; Rondeau, E; Uzan, M; Viron, B; Volochine, L, 1988) |
| " Similar findings were obtained in rats with CCl4 liver damage or gentamicin nephrotoxicity, except that those rats hardly exhibited anemia because of a simultaneous occurrence of hemoconcentration." | 3.67 | The influence of single or repeated phlebotomy on the physiological condition of normal and diseased rats. ( Furuhama, K; Igarashi, K; Kato, M; Onodera, T; Suzuki, N, 1987) |
| "The effect of aging on the total body clearance, volume of distribution, and half-life of gentamicin was examined in 99 febrile patients with various degrees of renal function." | 3.67 | Gentamicin disposition in young and elderly patients with various degrees of renal function. ( Halstenson, CE; Jameson, JJ; Matzke, GR, 1987) |
| "29 patients with serious renal or urinary tract infections were treated with netilmicin (initial dose 1." | 3.66 | Netilmicin therapy of serious renal and urinary tract infections in patients with normal and impaired renal function. ( Denneberg, T; Haeger, K; Juhlin, I, 1980) |
| "The purpose of this study was to examine the pharmacokinetics of gentamicin renal uptake in dogs and assess the role of chronic renal ischemia." | 3.66 | Renal handling of gentamicin by normal and ischemic canine kidneys. ( Adelman, MH; Harrison, NJ; Schentag, JJ; Wels, PB, 1982) |
| " coli-pyelonephritis facilitated by oestradiolundecylate, aminonucleoside nephrosis, aminoglycoside induced renal lesions and pyelonephritic animals treated with therapeutic and toxic doses of tobramycin." | 3.65 | The diagnostic value of enzymuria, cell excretion, and proteinuria in experimental renal diseases. ( Sack, K; Wilhelm, J, 1975) |
| "Calcium dobesilate is an antioxidant drug and this study is aimed to investigate the effects of calcium dobesilate on gentamicin-induced nephrotoxicity." | 2.79 | Calcium dobesilate for prevention of gentamicin-induced nephrotoxicity in rats. ( Changizi Ashtiyani, S; Jafarey, M; Najafi, H, 2014) |
| " Single daily dosing with GM, regardless of the total daily dose, produced less nephrotoxicity than multiple dosing." | 2.74 | A prospective comparative study of gentamicin- and amikacin-induced nephrotoxicity in patients with normal baseline renal function. ( Sweileh, WM, 2009) |
| " A control group (saline, group 1, n = 5) was compared with dogs that were administrated gentamicin by intramuscular injection, at dosage of 20 mg/kg, once daily for 9 days (groups 2-5, n = 5 per group)." | 2.73 | Effect of silymarin and vitamin E on gentamicin-induced nephrotoxicity in dogs. ( Avizeh, R; Esmailzadeh, S; Givi, ME; Morovvati, H; Shahriari, A; Varzi, HN, 2007) |
| "To evaluate whether individualized pharmacokinetic dosing of aminoglycosides can reduce nephrotoxicity and improve the outcome of patients with gram-negative sepsis." | 2.71 | Pharmacokinetic dosing of aminoglycosides: a controlled trial. ( Alkan, M; Almog, Y; Bartal, C; Danon, A; Reisenberg, K; Schlaeffer, F; Sidi, A; Smoliakov, R, 2003) |
| "To examine the safety and efficacy of once-daily (OD) gentamicin treatment compared with conventional 8-hourly dosing (TDS) for urinary tract infection (UTI)." | 2.71 | Treatment of urinary tract infection with gentamicin once or three times daily. ( Balakrishnan, A; Chao, SM; Chong, CY; Ng, W; Tan, AS; Tan-Kendrick, A, 2003) |
| "Intravenous bolus administration was safe in pediatric patients and was associated with lower costs." | 2.70 | Safety of intravenous bolus administration of gentamicin in pediatric patients. ( Nahata, MC; Robinson, RF, 2001) |
| " Once daily dosage can achieve the equivalent efficacy compared to a twice-daily dosage regimen." | 2.70 | Gentamicin in neonatal infection: once versus twice daily dosage. ( Ayudhya, DP; Chotigeat, U; Narongsanti, A, 2001) |
| "There is no established dosing schedule for once-daily aminoglycoside dosing regimens, and accepted guidelines for monitoring therapy are lacking." | 2.68 | Validation and nephrotoxicity of a simplified once-daily aminoglycoside dosing schedule and guidelines for monitoring therapy. ( de Blok, K; Prins, JM; Speelman, P; van Ketel, RJ; Weverling, GJ, 1996) |
| " (with dosage reduction in case of renal dysfunction)." | 2.67 | Once-daily gentamicin versus once-daily netilmicin in patients with serious infections--a randomized clinical trial. ( Büller, HR; Kuijper, EJ; Prins, JM; Speelman, P; Tange, RA, 1994) |
| " This was the first investigation of a once-daily dosing regimen conducted in seriously ill patients with systemic infections." | 2.67 | Does administration of an aminoglycoside in a single daily dose affect its efficacy and toxicity? ( Cronberg, S; Nordström, L; Ringberg, H; Tjernström, O; Walder, M, 1990) |
| "Netilmicin or tobramycin was administered to 197 patients in a prospective randomized double-blind trial." | 2.65 | Prospective randomized double-blind comparison of nephrotoxicity and auditory toxicity of tobramycin and netilmicin. ( Araujo, V; Bohe, M; Bonet, M; Ferrer, M; Gatell, JM; Jimenez de Anta, MT; Maña, J; SanMiguel, JG; Zamora, L, 1984) |
| " There was no statistical difference between the nephrotoxic and auditory toxic groups in patient age, total dose of aminoglycoside, initial creatinine level, duration of therapy, or concurrent use of furosemide or cephalothin." | 2.65 | Relationship between aminoglycoside-induced nephrotoxicity and auditory toxicity. ( Lietman, PS; Lipsky, JJ; Smith, CR, 1979) |
| "In patients with impaired renal function, careful adjustment of gentamicin dosage is required to achieve therapeutic yet nontoxic concentrations." | 2.64 | Prospective comparative study of variable dosage and variable frequency regimens for administration of gentamicin. ( Goodman, EL; Holmes, R; Hull, AR; Sanford, JP; Van Gelder, J, 1975) |
| "Gentamicin blood levels were monitored in 86 patients." | 2.64 | Gentamicin blood levels: a guide to nephrotoxicity. ( Anderson, ET; Dahlgren, JG; Hewitt, WL, 1975) |
| " As the use of aminoglycosides became more widespread, the toxic effects of these agents, most notably ototoxicity and nephrotoxicity, became more apparent." | 2.50 | Aminoglycoside-induced nephrotoxicity. ( Edwards, JD; Wargo, KA, 2014) |
| " The purpose of this review is to critically assess the published literature regarding the toxic mechanisms of action of aminoglycosides on renal glomeruli and mesangial cells." | 2.44 | Glomerular nephrotoxicity of aminoglycosides. ( López-Hernández, FJ; López-Novoa, JM; Martínez-Salgado, C, 2007) |
| "Renal involvement in patients with multiple myeloma complicates their treatment and shortens their life-span." | 2.44 | Renoprotection by pituitary adenylate cyclase-activating polypeptide in multiple myeloma and other kidney diseases. ( Arimura, A; Batuman, V; Lertora, JJ; Li, M; Maderdrut, JL, 2008) |
| "Sisomicin is a naturally occurring aminoglycoside antibiotic produced by Micromonospora inyoensis, while dibekacin and netilmicin are both semisynthetic aminoglycosides." | 2.37 | Sisomicin, netilmicin and dibekacin. A review of their antibacterial activity and therapeutic use. ( Noone, P, 1984) |
| " The advantages and disadvantages of arbitrary, predictive, and pharmacokinetic methods of dosing determination are summarized." | 2.37 | Clinical pharmacokinetics, toxicity and cost effectiveness analysis of aminoglycosides and aminoglycoside dosing services. ( Bailie, GR; Mathews, A, 1987) |
| " Despite the use of dosing nomograms, nephrotoxicity still occurs in some patients and the decline in renal function may only become apparent after completion of the antibiotic course." | 2.36 | Aminoglycoside nephrotoxicity: pathogenesis and prevention. ( Cronin, RE, 1979) |
| "Gentamicin is an essential aminoglycoside antibiotic, but it is only used to treat severe bacterial infections due to its high nephrotoxicity in patients." | 1.91 | Diosmin prophylaxis reduces gentamicin-induced kidney damage in rats. ( Geshnigani, SSH; Goudarzi, M; Kalantar, H; Kalantar, M; Khorsandi, L; Mahdavinia, M, 2023) |
| "Gentamicin (GM) is an aminoglycoside antibiotic which is commonly used against Gram-negative bacterial infection; however, serious complications including nephrotoxicity could limit its clinical use." | 1.72 | Curcumin protects rats against gentamicin-induced nephrotoxicity by amelioration of oxidative stress, endoplasmic reticulum stress and apoptosis. ( Arjinajarn, P; Cherngwelling, R; Laorodphun, P; Panya, A, 2022) |
| "Gentamicin (GM) is a commonly prescribed antimicrobial drug used for treatment of infections but associated hepatic and renal complications restrict its efficacy." | 1.62 | The potential antioxidant bioactivity of date palm fruit against gentamicin-mediated hepato-renal injury in male albino rats. ( Abdeen, A; Abdelkader, A; Abdullah, O; Aboubaker, M; Alsanie, WF; Baioumy, B; Elkomy, A; Elnoury, HA; Gaber, A; Habotta, OA; Ibrahim, SF; Samir, A, 2021) |
| "Gentamicin (GM) is a low-cost, low-resistance antibiotic commonly used to treat gram-negative bacterial diseases." | 1.62 | Assessment of gentamicin and cisplatin-induced kidney damage mediated via necrotic and apoptosis genes in albino rats. ( Abouzed, TK; Aldhahrani, A; Barakat, MES; Dorghamm, DA; Eldomany, E; Khailo, K; Nasr, NE; Sadek, KM; Sherif, EAE, 2021) |
| "To determine the rate of and predictors for guideline-discordant preoperative gentamicin dosing in urologic surgery and to assess the risk of nephrotoxicity in patients who receive the recommended high-dose prophylaxis." | 1.62 | Guideline-Discordant Preoperative Gentamicin Dosing and the Risk of Gentamicin Associated Nephrotoxicity in Urologic Surgery. ( Aaron, JG; Anderson, CB; Barone, JC; Kubin, CJ; Kurtzman, JT; Li, G; Margolin, EJ, 2021) |
| "Gentamicin is an aminoglycoside antibiotic commonly administrated to patients with Gram-negative infections." | 1.56 | Toll-like receptor-2 mediates systemic inflammation in gentamicin-induced rat nephrotoxicity. ( Janfeshan, S; Karimi, Z; Pakfetrat, Z; Roozbeh, J, 2020) |
| " This finding could be of great importance for the wider use of aminoglycosides, with therapy that would reduce the occurrence of serious adverse effects, such as nephrotoxicity and acute renal failure." | 1.51 | Pioglitazone attenuates kidney injury in an experimental model of gentamicin-induced nephrotoxicity in rats. ( Divac, N; Jovanović, GB; Kekić, D; Medić, B; Prostran, M; Radenković, M; Rovčanin, B; Škodrić, SR; Stojanović, M; Stojanović, R; Vujović, KS, 2019) |
| "MS extract can protect the kidney against toxic effects of gentamicin, and thus, the degree of harmful effects of nephrotoxicity on remote organs including the liver will be decreased." | 1.51 | Amelioration of renal and hepatic function, oxidative stress, inflammation and histopathologic damages by Malva sylvestris extract in gentamicin induced renal toxicity. ( Jassemi, SV; Madani, SH; Modarresi, M; Mohamadi Yarijani, Z; Najafi, H; Shackebaei, D, 2019) |
| " Before employing this dietary model to humans, further investigation is necessitated to observe safety in long-term administration of such products." | 1.51 | Nephroprotective effects of red beetroot-based beverages against gentamicin-induced renal stress. ( Butt, MS; Randhawa, MA; Shahid, M, 2019) |
| "The major side effect of gentamicin (GEN) is nephrotoxicity which in turn restricts the clinical use of this drug." | 1.48 | Ameliorative effects of gallic acid on gentamicin-induced nephrotoxicity in rats. ( Fatemi, I; Ghaznavi, H; Gholamine, B; Goudarzi, M; Hosseini Tabatabaei, SMT; Kalantar, M; Kalantari, H; Mehrabani, M; Mehrzadi, S, 2018) |
| "Nephrotoxicity is a serious adverse effect frequently encountered with aminoglycosides administration." | 1.48 | Nephroprotective effect of saxagliptin against gentamicin-induced nephrotoxicity, emphasis on anti-oxidant, anti-inflammatory and anti-apoptic effects. ( Helal, MG; Said, E; Zaki, MMAF, 2018) |
| "Gentamicin is an aminoglycoside antibiotic widely used for the treatment of life-threatening infections caused by Gram-negative bacteria." | 1.48 | Protective effect of Rotula aquatica Lour against gentamicin induced oxidative stress and nephrotoxicity in Wistar rats. ( A, V; Jyothis, M; Kuriakose, J; Latha, MS; Midhun, SJ; S, A, 2018) |
| " The known oto- and nephrotoxicity associated with aminoglycosides preclude long-term use as readthrough agents." | 1.48 | The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential. ( Babu, S; Baiazitov, R; Branstrom, A; Colacino, JM; Elfring, G; Friesen, WJ; Hedrick, J; Johnson, B; Mollin, A; Moon, YC; Morrill, C; Peltz, SW; Ren, H; Sheedy, J; Sierra, J; Tomizawa, Y; Vazirani, P; Weetall, M; Welch, EM; Xue, X; Zhuo, J, 2018) |
| "Gentamicin is a potent aminoglycoside antibiotic, but the risk of nephrotoxicity limits its prolonged use." | 1.46 | Kiwi fruit (Actinidia deliciosa) ameliorates gentamicin-induced nephrotoxicity in albino mice via the activation of Nrf2 and the inhibition of NF-κB (Kiwi & gentamicin-induced nephrotoxicity). ( Mahmoud, YI, 2017) |
| "Gentamicin is an aminoglycoside antibiotic widely used in the treatment of infections caused by Gram-negative bacteria." | 1.46 | Renoprotective effect of erythropoietin in zebrafish after administration of gentamicin: an immunohistochemical study for β-catenin and c-kit expression. ( Buemi, A; Buemi, M; Cernaro, V; Costantino, G; Lacquaniti, A; Macrì, F; Maricchiolo, G; Ricciardi, CA; Rifici, C; Santoro, D; Sfacteria, A, 2017) |
| "Gentamicin led to increase in plasma BUN and creatinine, fractional excretion of sodium and potassium and decrease in creatinine clearance and urine flow rate." | 1.46 | Protective effects of hydroxytyrosol on gentamicin induced nephrotoxicity in mice. ( Chashmi, NA; Emadi, S; Khastar, H, 2017) |
| "Treatment with gentamicin induced a dose-dependent increase in kidney tubular cell degeneration/necrosis, ranging from minimal to mild severity at 10mg/kg/day, moderate at 25mg/kg/day, and to severe at 50mg/kg/day." | 1.43 | Evaluation of novel biomarkers of nephrotoxicity in Cynomolgus monkeys treated with gentamicin. ( Boitier, E; Detilleux, P; Filali-Ansary, A; Gautier, JC; Guizon, I; Gury, T; Joos, T; Léonard, JF; Li, B; Palazzi, X; Poetz, O; Qu, Z; Slaoui, M; van den Berg, BHJ; Veeranagouda, Y; Wang, J; Yang, Y; Zhang, T; Zhou, X, 2016) |
| "Ellagic acid treatment significantly reduced plasma creatinine and urea levels, which were initially increased due to GEN administration." | 1.43 | Ellagic acid confers protection against gentamicin-induced oxidative damage, mitochondrial dysfunction and apoptosis-related nephrotoxicity. ( Aghsami, M; Ghahremani, MH; Keshavarz-Bahaghighat, H; Rajabi, J; Razavi-Azarkhiavi, K; Sepand, MR; Soodi, M, 2016) |
| " End points included the numbers (%) achieving the target peak concentration [predicted maximum gentamicin concentration (C(max))] >10 mg/L, the target trough concentration at 24 hours [predicted minimum gentamicin concentration (C(min24)] <0." | 1.42 | Gentamicin and renal function: lessons from 15 years' experience of a pharmacokinetic service for extended interval dosing of gentamicin. ( Begg, EJ; Buffery, PJ; Chin, PK; Plajer, SM; Vella-Brincat, JW, 2015) |
| "(1) Gentamicin release was sustained over 7 days with the higher-dose formulation release profile similar to release from high-dose antimicrobial-loaded bone cement." | 1.42 | Local gentamicin delivery from resorbable viscous hydrogels is therapeutically effective. ( Calara, F; McLaren, A; McLemore, R; Overstreet, D; Vernon, B, 2015) |
| " However, it is not yet resolved if such drug-induced adverse effects are independent or interdependent phenomena." | 1.42 | Gentamicin-induced ototoxicity and nephrotoxicity vary with circadian time of treatment and entail separate mechanisms. ( Blunston, MA; Smolensky, MH; Woodahl, EL; Yonovitz, A, 2015) |
| "Aliskiren treatment attenuated the decreased creatinine clearance, increased fractional sodium excretion, glomerulosclerosis and tubulointerstitial fibrosis and counteracted the increased ED-1 expression in gentamicin-treated rats." | 1.40 | Renoprotective effects of the direct renin inhibitor aliskiren on gentamicin-induced nephrotoxicity in rats. ( Bae, EH; Choi, JS; Joo, SY; Kim, CS; Kim, EY; Kim, IJ; Kim, SW; Lee, J; Ma, SK, 2014) |
| "Coenzyme Q10 is a natural antioxidant and scavenger of free radicals." | 1.40 | Serum paraoxonase 1 status and its association with atherogenic indexes in gentamicin-induced nephrotoxicity in rats treated with coenzyme Q10. ( Ahmadvand, H; Bagheri, S; Cheraghi, RA; Dehghani, A; Ghasemi Dehnoo, M, 2014) |
| "Differences were examined between male and female Sprague-Dawley rats in the response of 16 urinary biomarkers (measured using several assay platforms) to renal injury produced by gentamicin administered subcutaneously for 10 days at a dosage of 75 mg/kg." | 1.40 | Comparison between male and female Sprague-Dawley rats in the response of urinary biomarkers to injury induced by gentamicin. ( Gautier, JC; Guffroy, M; Gury, T; Harpur, E; Hoffman, D; Khan-Malek, R; Masson, R; Pettit, S, 2014) |
| " The inability of BSS to protect against gentamicin nephrotoxicity was likely due to the relatively low bioavailability of BSS in rat kidneys." | 1.40 | β-sitosterol protects against carbon tetrachloride hepatotoxicity but not gentamicin nephrotoxicity in rats via the induction of mitochondrial glutathione redox cycling. ( Chan, WM; Chen, JH; Ko, KM; Leong, PK; Leung, HY; Wong, HS, 2014) |
| "Gentamicin was injected intraperitoneally (100 mg/kg body weight) once daily for 8 days to induce nephrotoxicity." | 1.39 | Histone deacetylase inhibitor, sodium butyrate, attenuates gentamicin-induced nephrotoxicity by increasing prohibitin protein expression in rats. ( Hong, X; Kong, X; Sun, X; Zhang, B; Zhang, X, 2013) |
| "Gentamicin and vitamin C have been proposed as nephrotoxic and antioxidant, respectively." | 1.38 | A biochemical and histopathologic study showing protection and treatment of gentamicin-induced nephrotoxicity in rabbits using vitamin C. ( Abid, R; Akash, MS; Azhar, S; Khan, SA; Murtaza, G; Rehman, K; Sherazi, TA; Waseem, A, 2012) |
| "Relationship between vestibulotoxicity and gentamicin dose or dosing profile; indications for prescribing gentamicin." | 1.38 | Gentamicin ototoxicity: a 23-year selected case series of 103 patients. ( Ahmed, RM; Chan, RC; Halmagyi, GM; Hannigan, IP; MacDougall, HG, 2012) |
| "Uranium is a radioactive heavy metal with a predominantly chemical toxicity, affecting especially the kidneys and more particularly the proximal tubular structure." | 1.37 | Effect of nephrotoxic treatment with gentamicin on rats chronically exposed to uranium. ( Baudelin, C; Dublineau, I; Grandcolas, L; Grison, S; Gueguen, Y; Pallardy, M; Rouas, C; Stefani, J, 2011) |
| " In conclusion, NS acts in the kidney as a potent scavenger of free radicals to prevent the toxic effects of GS both in the biochemical and histopathological parameters." | 1.36 | Protective effects of nigella sativa against gentamicin-induced nephrotoxicity in rats. ( Balikci, E; Yaman, I, 2010) |
| "Oleanolic acid is a molecule of current therapeutic interest." | 1.36 | Protective effect of oleanolic acid on gentamicin induced nephrotoxicity in rats. ( Jadhav, RB; Mundada, S; Patil, CR; Patil, PR; Singh, PK, 2010) |
| "The gentamicin-treated group showed a marked increase in SCr compared to the normal control group." | 1.36 | The modifier protein of glyceraldehyde-3-phosphate dehydrogenase reduces free radical-mediated renal damage in a rat model of acute kidney injury. ( Fan, QL; Li, ZL; Liang, ZF; Ma, JF; Ren, Q; Sun, YH; Wang, J; Wang, LN, 2010) |
| "Gentamicin (G) is a highly nephrotoxic aminoglucoside." | 1.36 | Attenuation of gentamicin-induced nephrotoxicity: trimetazidine versus N-acetyl cysteine. ( Araujo, CR; De la Cruz Rodríguez, LC; Posleman, SE; Rey, MR, 2010) |
| "Metformin treatment fully blocked gentamicin-mediated acute renal failure." | 1.36 | Metformin prevents experimental gentamicin-induced nephropathy by a mitochondria-dependent pathway. ( Arévalo, M; Briones, E; Detaille, D; El-Mir, MY; Leverve, X; López-Novoa, JM; Morales, AI; Prieto, M; Puente, A, 2010) |
| " To date, the use of these formulas in determining drug dosage and estimating drug elimination has not been thoroughly investigated." | 1.35 | Modification of Diet in Renal Disease and modified Cockcroft-Gault formulas in predicting aminoglycoside elimination. ( Bookstaver, PB; Johnson, JW; McCoy, TP; Stewart, D; Williamson, JC, 2008) |
| "Gentamicin (GM) is an antibiotic widely used in treating severe gram-negative infections." | 1.35 | Protective effect of quercetin against gentamicin-induced nephrotoxicity in rats. ( Abdel-Ghany, AA; Abdel-Raheem, IT; Mohamed, GA, 2009) |
| "The treatment of L-carnitine also lessened gentamicin-induced renal tubular cell apoptosis in mice." | 1.35 | Peroxisome proliferator-activated receptor alpha plays a crucial role in L-carnitine anti-apoptosis effect in renal tubular cells. ( Chen, CH; Chen, HH; Chen, TH; Chen, TW; Cheng, CY; Hou, CC; Hsu, YH; Lin, SL; Sue, YM; Tsai, WL, 2009) |
| " The specificity of acute kidney injury (AKI) biomarkers, iNOS, and nitrotyrosine was evaluated by dosing rats with valproic acid (VPA)." | 1.35 | Differences in immunolocalization of Kim-1, RPA-1, and RPA-2 in kidneys of gentamicin-, cisplatin-, and valproic acid-treated rats: potential role of iNOS and nitrotyrosine. ( Bonventre, JV; Brown, RP; Espandiari, P; Goering, PL; Hanig, JP; Keenan, J; Kilty, CG; Sadrieh, N; Shaw, M; Vaidya, VS; Zhang, J, 2009) |
| " Male Sprague-Dawley rats were dosed daily for 1, 3 or 5 days to the known nephrotoxicants gentamicin, bacitracin, vancomycin and cisplatin, or the known hepatotoxicants ketoconazole, 1-naphthyl isothiocyanate and 4,4-diaminodiphenylmethane." | 1.35 | Validation of putative genomic biomarkers of nephrotoxicity in rats. ( Fielden, MR; Gu, YZ; Smith, RJ; Snyder, RD; Wang, EJ, 2008) |
| "Gentamicin (GM) is an antibiotic whose clinical use is limited by its nephrotoxicity." | 1.34 | Effect of carnosine on gentamicin-induced nephrotoxicity. ( Abdul-Hamid, M; Othman, AI; Soliman, KM, 2007) |
| "Corticosterone was assayed to quantify the stress of the animals." | 1.34 | Dietary protein level alters gentamicin-induced nephrotoxicity in rats. ( Beauchamp, D; Labrecque, G; Selmaoui, B; Thibault, L; Zeeni, N, 2007) |
| "Gentamicin (GM) is an effective antibiotic against severe gram-negative infections." | 1.33 | Effects of co-supplementation of vitamins E and C on gentamicin-induced nephrotoxicity in rat. ( Faghihi, M; Ghaznavi, R; Kadkhodaee, M; Khastar, H; Zahmatkesh, M, 2005) |
| " The introduction of a gentamicin monitoring form was prompted by unsatisfactory initial dosing and subsequent monitoring and adjustment of gentamicin doses." | 1.33 | Improved compliance with a gentamicin prescribing policy after introduction of a monitoring form. ( Boxall, EM; Chadwick, PR; Cullen, MM; Rogers, MS, 2005) |
| "Gentamicin is an antibiotic that is widely used against serious and life-threatening gram-negative infections." | 1.33 | Protective effect of ebselen, a selenoorganic drug, against gentamicin-induced renal damage in rats. ( Abraham, P; Dhanarajan, R; Isaac, B, 2006) |
| "Although fitting orders to renal function avoids overdosage and therefore iatrogenic risk, dosage adjustment is rarely made." | 1.32 | Assessing residents' prescribing behavior in renal impairment. ( Brücker, G; Deray, G; Launay-Vacher, V; Levu, S; Ravaud, P; Salomon, L, 2003) |
| "Gentamicin (GM) is an antibiotic whose clinical use is limited by its nephrotoxicity." | 1.32 | Aged garlic extract attenuates gentamicin induced renal damage and oxidative stress in rats. ( Barrera, D; Hernández-Pando, R; Ibarra-Rubio, ME; Maldonado, PD; Medina-Campos, ON; Pedraza-Chaverrí, J, 2003) |
| " indicus) was relatively safe up to 7 g/kg bodyweight dose." | 1.32 | Renoprotective effect of Hemidesmus indicus, a herbal drug used in gentamicin-induced renal toxicity. ( Kotnis, MS; Menon, SN; Patel, P; Sane, RT, 2004) |
| "Treatment with verapamil induced a dose-dependent potentiation in the biochemical parameters of nephrotoxicity that was significant only at the highest dose used (7 mg/kg)." | 1.31 | The effect of calcium load and the calcium channel blocker verapamil on gentamicin nephrotoxicity in rats. ( Al-Qarawi, AA; Ali, BH; Mousa, HM, 2002) |
| "Gentamicin treatment at 1300 or 0100 h resulted in a decrease in the 24-h food intake." | 1.31 | Temporal modulation of nephrotoxicity, feeding, and drinking in gentamicin-treated rats. ( Beauchamp, D; Julien, N; Karzazi, M; Labrecque, G; Thibault, L, 2000) |
| "To evaluate traditional nomogram (TN) versus individualized pharmacokinetic gentamicin dosing practices in neonatal intensive care units, focusing on achieving target therapeutic concentrations (peak > 8 microg/ml, trough < 2 microg/ml), number of dosing changes, number of concentrations obtained, and evidence of nephrotoxicity." | 1.31 | A multicenter evaluation of gentamicin therapy in the neonatal intensive care unit. ( Cole, E; Cuthrell, C; Gal, P; Glover, ML; Potter, D; Ransom, JL; Rubino, CM; Schoening, S; Shaffer, CL, 2001) |
| "To examine the impact of individualized pharmacokinetic monitoring (IPM) on the development of aminoglycoside-associated nephrotoxicity (AAN)." | 1.31 | Individualized pharmacokinetic monitoring results in less aminoglycoside-associated nephrotoxicity and fewer associated costs. ( Bertino, AS; Destache, CJ; Nafziger, AN; Streetman, DS, 2001) |
| "Gentamicin treatment produced significant elevation in serum total cholesterol, which was greater in animals fed with CSD." | 1.31 | Effect of high dietary cholesterol on gentamicin-induced nephrotoxicity in rabbits. ( Abdel-Gayoum, AA; Abu-Spetan, KA, 2001) |
| "There remain concerns about the safety of once-daily dosing of aminoglycosides (AGs) in the elderly." | 1.31 | Risk factors for nephrotoxicity in elderly patients receiving once-daily aminoglycosides. ( Hite, Y; Kopyt, M; Raveh, D; Rudensky, B; Sonnenblick, M; Yinnon, AM, 2002) |
| "The effect of timing of gentamicin dosing relative to food access periods was evaluated in experimental animals." | 1.30 | Time-restricted feeding schedules modify temporal variation of gentamicin experimental nephrotoxicity. ( Beauchamp, D; Bergeron, MG; Gourde, P; Grenier, L; Guimont, C; Labrecque, G; LeBrun, M; Tardif, D; Thibault, L, 1997) |
| "In gentamicin-treated rats with tubular dysfunction, up to 30% of the pentosidine load was recovered as intact pentosidine in the urine." | 1.30 | Renal catabolism of advanced glycation end products: the fate of pentosidine. ( Horie, K; Kurokawa, K; Miyata, T; Nangaku, M; Tanaka, S; Ueda, Y; van Ypersele de Strihou, C, 1998) |
| "A serious undesired action of the large group of cytostatics and aminoglycoside antibiotics is their side effect on the kidney." | 1.30 | Enzymes in urine as markers of nephrotoxicity of cytostatic agents and aminoglycoside antibiotics. ( Długosz, A; Marchewka, Z, 1998) |
| "Gentamicin treatment causes tubular necrosis at day 3, followed by tubular regenerative changes and interstitial fibrosis, which was most prominent at day 14." | 1.30 | Expression of the heat shock protein 47 in gentamicin-treated rat kidneys. ( Cheng, M; Nazneen, A; Razzaque, MS; Taguchi, T, 1998) |
| "Postoperative renal dysfunction in rats is induced by ketorolac dosed concurrently with gentamicin." | 1.30 | Renal dysfunction associated with the perioperative use of diclofenac. ( Cousins, MJ; Eckstein, RP; Jordan, V; Kim, H; Lin, Y; Mather, LE; Power, I; Xu, M, 1999) |
| " The measurement of gamma-glutamyl transpeptidase activity in urine can be applied as a useful parameter on determination of nephrotoxicity, especially for indicating the dimensions of this toxic effect." | 1.29 | Study on the role of urine gamma-glutamyl transpeptidase activity during investigation of nephrotoxicity. ( Başdemir, G; Berkan, T; Karan, A; Kocaoğlu, S, 1994) |
| "Once-daily administration of aminoglycosides may be a safe and effective therapeutic regimen, on the basis of the microbiologic and pharmacokinetic characteristics of these antibiotics." | 1.29 | Pharmacokinetics, nephrotoxicosis, and in vitro antibacterial activity associated with single versus multiple (three times) daily gentamicin treatments in horses. ( Derksen, FJ; Godber, LM; Hauptman, JG; Stein, GE; Walker, RD, 1995) |
| "Verapamil was given as a sustained release preparation of 180 mg twice daily starting 2 days before the aminoglycoside, and continued for 4 days post-gentamicin therapy." | 1.29 | The effect of verapamil on the nephrotoxic potential of gentamicin as measured by urinary enzyme excretion in healthy volunteers. ( Goldfarb, AL; Kazierad, DJ; Nix, DE; Schentag, JJ; Wojcik, GJ, 1995) |
| "The allopurinol only treatment group demonstrated no noticeable histological or functional changes considered to be indicative of nephrotoxicity." | 1.29 | Allopurinol fails to protect against gentamicin-induced renal damage in normotensive and spontaneously hypertensive rats. ( Davis, WG; Smyth, BJ, 1994) |
| "Methimazole did not inhibit GM renal uptake but may protect against GM-induced nephrotoxicity by acting as an antioxidant within the kidneys." | 1.29 | Methimazole protection of rats against gentamicin-induced nephrotoxicity. ( Cooley, AJ; Duescher, RJ; Elfarra, AA; O'Hara, TM; Sausen, PJ, 1994) |
| "2." | 1.29 | Plasma lipid profile in rats with gentamicin-induced nephrotoxicity. ( Abdel-Gayoum, AA; Ali, BH; Bashir, AA; Ghawarsha, K, 1993) |
| " After the conditioning period, gentamicin was administered at a dosage of 10 mg/kg of body weight, IM, every 8 hours for 8 days, and the respective diet was continued." | 1.29 | Effects of dietary protein conditioning on gentamicin-induced nephrotoxicosis in healthy male dogs. ( Allen, TA; Behrend, EN; Fettman, MJ; Grauer, GF; Greco, DS; Jaenke, RS, 1994) |
| " We conclude that as far as the vestibular system is concerned there is no safe gentamicin dose and no safe serum gentamicin level, and there is an increased risk of vestibulotoxicity in patients in whom nephrotoxicity develops." | 1.29 | Gentamicin vestibulotoxicity. ( Curthoys, IS; Fattore, CM; Halmagyi, GM; Wade, S, 1994) |
| " We administered three fourth of LD50 of each agent to male Fischer 344 rats, intra-peritoneally." | 1.29 | [Study on gamma-GTP activity in urine and renal tissue of drug-induced nephrotoxicity in rats]. ( Furuta, N; Nakada, J, 1993) |
| "We studied the use of aminoglycosides at King Abdulaziz University Hospital (KAUH), Jeddah, Saudi Arabia, including prescriptions, dosage, serum levels, toxic factors and treatment outcome." | 1.29 | Aminoglycoside prescription, therapeutic monitoring and nephrotoxicity at a university hospital in Saudi Arabia. ( Bahnassy, AA; Eltahawy, AT, 1996) |
| "In verapamil-treated rats (5 mg/kg/day), no histological or biochemical evidence of renal injury was detected." | 1.28 | Verapamil increases the nephrotoxic potential of gentamicin in rats. ( Fadali, GA; Farag, MM; Kandil, M, 1992) |
| "01) compared with rats dosed with GT alone." | 1.28 | Epidermal growth factor accelerates renal tissue repair in a model of gentamicin nephrotoxicity in rats. ( Beauchamp, D; Bergeron, MG; Heuson-Stiennon, JA; Laurent, G; Morin, NJ; Nonclercq, D; Toubeau, G, 1992) |
| " A stepwise reduction in nephroprotection occurred as the dosage interval was prolonged." | 1.28 | Duration of the protective effect of polyaspartic acid on experimental gentamicin nephrotoxicity. ( Bennett, WM; Gilbert, DN; Kohlhepp, SJ; Kohnen, PW; Leggett, JE; Swan, SK, 1992) |
| "Some pharmacokinetic and pharmacodynamic interactions between digoxin and gentamicin were studied in experiments on rabbits, guinea-pigs and cats." | 1.28 | Some pharmacokinetic and pharmacodynamic interactions between digoxin and gentamicin. ( Kristeva, E; Prodanova, K; Staneva-Stoytcheva, D, 1991) |
| " During the next three years, of 912 patients given two to three days gentamicin, 29 patients were shown to have potentially toxic serum levels and oliguria." | 1.28 | Aminoglycoside toxicity following antibiotic prophylaxis in cardiac surgery. ( Sturridge, MF; Treasure, T; Wilson, AP, 1990) |
| " Toxic doses of lipopolysaccharide (5 mg/kg) and HgCl2 (3." | 1.28 | Extracellular DNA in blood and urine as a potential marker for cytotoxicity and nephrotoxicity in the mouse. ( Bret, L; Fournié, GJ; Lulé, J; Pourrat, JP, 1990) |
| "Gentamicin treatment alone induced typical renal lesions which were scored as moderate and a slight but significant decrease in ACE blood levels." | 1.28 | Modulation of gentamicin nephrotoxicity by chronic inhibition of angiotensin-I-converting enzyme in rat. ( Borghi, H; Fillastre, JP; Morin, JP; Thomas, N; Toutain, H, 1989) |
| "The effect of age and renal function on gentamicin pharmacokinetic parameters were studied in 125 patients with various degrees of renal function." | 1.28 | Effect of age and renal function on gentamicin pharmacokinetic parameters. ( el-Sayed, YM; Islam, SI, 1989) |
| " Ribostamycin caused slightly less nephrotoxicity in rats than kanamycin and far less than dibekacin at an equal dosage of 40 mg/kg per day for 14 days." | 1.28 | Comparative nephrotoxicity of ribostamycin and gentamicin in rats evaluated by urinalysis. ( Inouye, S; Kitasato, I; Niizato, T, 1989) |
| " No pharmacokinetic differences were seen in half-life, volume of distribution (liter per kilogram; total and ideal body weight), or clearance (milliliter per minute per 1." | 1.28 | Gentamicin pharmacokinetics, nephrotoxicity, and prediction of mortality in febrile neutropenic patients. ( Bertino, JS; Bianco, TM; Dwyer, PN, 1989) |
| " Bile duct ligated and gentamicin injected rats elicited a decline in renal function and tubular cell necrosis after 8 days of treatment whereas equal dosage regimen in sham operated rats exhibited no evidence of renal dysfunction." | 1.28 | Enhanced gentamicin nephrotoxicity after experimental biliary obstruction in rats. ( Andrade, RJ; Gonzalez-Correa, JA; Ibañez, J; Lucena, MI; Sanchez de la Cuesta, F; Torres, D, 1989) |
| "A population pharmacokinetic study was conducted on a total of 70 patients receiving gentamicin therapy." | 1.28 | Population pharmacokinetic study of gentamicin and a Bayesian approach in patients with renal impairment. ( Berrocal, A; Calvo, MV; de la Calle, B; Domínguez-Gil, A; Lanao, JM; Perez, M, 1989) |
| "Renal carbuncles have traditionally been treated with surgical drainage and appropriate antibiotic therapy." | 1.28 | Conservative management of renal carbuncles in children. ( Noe, HN; Whitfield, JD, 1989) |
| " Salt depletion resulted in an enhanced nephrotoxic response with a shift in the dose-response curve to the left." | 1.28 | Role of sodium in the protective effect of ticarcillin on gentamicin nephrotoxicity in rats. ( Branch, KR; Branch, RA; Bryant, TD; Ohnishi, A; Sabra, R, 1989) |
| " Serial pharmacokinetic dosing has been proposed as a method to achieve these goals." | 1.28 | Serial pharmacokinetic dosing of aminoglycosides: a community hospital experience. ( Hoffa, DE, 1989) |
| "We conclude that experimental extrahepatic cholestasis in the rat, in the absence of any other factor, potentiates gentamicin nephrotoxicity." | 1.28 | Gentamicin nephrotoxicity in extrahepatic cholestasis: modulation by dietary calcium. ( Abu-Alfa, A; Mujais, SK; Vakil, N, 1989) |
| "Gentamicin was chosen because it has been widely used, and a large portion of the body of knowledge concerning aminoglycosides involves gentamicin." | 1.27 | Patient selection for serum gentamicin levels. ( Crass, RE; Lampasona, V, 1983) |
| "Gentamicin clearance was measured in 26 patients by a method which requires four blood samples." | 1.27 | Clinical experience with a method for adjusting gentamicin dose from measured drug clearance. ( Davey, PG; Geddes, AM; Gonda, I; Harpur, ES; Scott, DK, 1983) |
| " No significant differences in clearance, volume of distribution or half-life were found due to age within a single drug group (amikacin, gentamicin, or tobramycin) or among the 3 drug groups." | 1.27 | Influence of age on amikacin pharmacokinetics in patients without renal disease. Comparison with gentamicin and tobramycin. ( Bauer, LA; Blouin, RA, 1983) |
| "Gentamicin was administered intramuscularly in a dose of 40 mg/kg/day for 12 days to adult Fischer rats." | 1.27 | Nitrendipine protects against aminoglycoside nephrotoxicity in the rat. ( Lee, SM; Michael, UF; Pattison, ME, 1987) |
| " In conclusion, if it could be necessary to use habekacin and to prefer this aminoglycoside to gentamicin from an antibacterial activity point of view it is necessary to keep in mind that this drug is potentially nephrotoxic and that the dosage had to be strictly respected." | 1.27 | [Habekacin: a new aminoglycoside. Study of nephrotoxicity in rats in comparison with gentamicin, netilmicin and amikacin]. ( Fillastre, JP; Morin, JP; Olier, B; Thomas, N, 1988) |
| "Gentamicin was administered at 40 mg/kg-day to C and C/I and 32 mg/kg-day to DM rats to adjust for base-line CIN." | 1.27 | Experimental gentamicin nephrotoxicity: effect of streptozotocin-induced diabetes. ( Baines-Hunter, J; Bennett, WM; Elliott, WC; Gilbert, DN; Houghton, DC, 1985) |
| "Gentamicin was given to six sheep at a dosage rate of 80 mg/kg/day divided into three daily doses to cause nephrotoxicity." | 1.27 | Comparison of serum and renal gentamicin concentrations with fractional urinary excretion tests as indicators of nephrotoxicity. ( Brown, SA; Garry, FB, 1988) |
| " The rabbits received gentamicin at equivalent therapeutic (5 and 20 mg/kg/j) or toxic (50 mg/kg/j) doses during four days." | 1.27 | [Urinary excretion of N-acetyl-beta-D-glucosaminidase (NAG) and its isoenzyme B as a marker of the nephrotoxicity of gentamicin: re-test from an animal model]. ( Ali-Miraftab, H; Bondiou, MT; Bourbouze, R; Percheron, F, 1988) |
| " Results of the study indicated the need to individualize aminoglycoside dosage regimens on the basis of pharmacokinetic disposition of drug, especially in dogs with preexisting subclinical renal dysfunction." | 1.27 | Gentamicin pharmacokinetics and nephrotoxicity in naturally acquired and experimentally induced disease in dogs. ( Aucoin, DP; Frazier, DL; Riviere, JE, 1988) |
| "When piperacillin was concomitantly administered with gentamicin, the elevations of blood urea nitrogen, serum creatinine, and urinary NAG were significantly lower than when gentamicin was given alone." | 1.27 | Protective effect of piperacillin against nephrotoxicity of cephaloridine and gentamicin in animals. ( Hayashi, T; Katahira, J; Kitayama, R; Kumada, T; Kumano, K; Saikawa, I; Shimizu, K; Watanabe, Y; Yasuda, T, 1988) |
| "Twenty-six subtotally nephrectomized dogs were used as a model for subclinical renal dysfunction to evaluate the nephrotoxic potential of gentamicin administered according to four different dosage regimens." | 1.27 | Gentamicin dosing strategies for dogs with subclinical renal dysfunction. ( Frazier, DL; Riviere, JE, 1987) |
| " Toxic trough levels of tobramycin (the most frequently used aminoglycoside) were seldom detected before the onset of nephrotoxicity, and peak tobramycin levels were frequently suboptimal." | 1.27 | Impact of aminoglycoside serum assays on clinical decisions and renal toxicity. ( Arroyo, JC; Davis, J; Milligan, WL; Mitchell, D, 1986) |
| " In addition, the subtotal Nx rat may thus be a valuable and economical model for assessing the nephrotoxicity of different drug dosage regimens in pre-existing renal disease." | 1.27 | Dose response studies of gentamicin nephrotoxicity in rats with experimental renal dysfunction. III. Effects of dosage adjustment method. ( Hanna, AY; Riviere, JE; Rogers, RA, 1987) |
| " Gentamicin at toxic doses, however, increased CSA nephrotoxicity." | 1.27 | Experimental cyclosporine nephrotoxicity: risk of concomitant chemotherapy. ( Mihatsch, MJ; Müller, AM; Ryffel, B, 1986) |
| "Only two patients developed transient acute renal failure during the first 10 days of treatment." | 1.27 | [Isoenzymes of N-acetyl-beta-D-glucosaminidase (NAG): new method of evaluating the nephrotoxicity of aminosides. Our experience with dibekacin in geriatrics]. ( Becker, M; Dupond, JL; Flausse-Parrot, F; Gibey, R; Guerber, F; Iehl-Robert, M; Mallet, H, 1986) |
| "Gentamicin treatment also caused increased urinary Ca++ excretion in control rats (from 2." | 1.27 | Effect of parathyroid hormone activity on gentamicin nephrotoxicity. ( Elliott, WC; Jones, DB; Patchin, DS, 1987) |
| "Amiloride, 2 mg/kg/day, was given to groups of 8-12 Fischer 344 rats receiving gentamicin, 20 mg/kg b." | 1.27 | Effect of amiloride on experimental gentamicin nephrotoxicity. ( Bennett, WM; Houghton, DC; Porter, GA; Purnell, J, 1985) |
| " This decreased fractional excretion of gentamicin implies that the quantity of drug excreted by the diseased kidney cannot be precisely predicted on the basis of glomerular filtration rate alone when drug dosage regimens are designed for patients with renal disease." | 1.27 | Decreased fractional renal excretion of gentamicin in subtotal nephrectomized dogs. ( Bowman, KF; Riviere, JE; Rogers, RA, 1985) |
| " The present study contrasted the dose-response nephrotoxicity of gentamicin in control rats with that of rats with renal insufficiency secondary to subtotal (2/3) surgical nephrectomy." | 1.27 | Dose-response studies of gentamicin nephrotoxicity in rats with experimental renal dysfunction. I. Subtotal surgical nephrectomy. ( Brown, TT; Carver, MP; Riviere, JE; Rogers, RA; Shy-Modjeska, JS, 1985) |
| "Following the previous report on pharmacokinetics of micronomicin (MCR) in healthy volunteers, pharmacokinetic studies were made again in patients with different degree of renal impairment, and a nomogram was obtained." | 1.27 | [Clinical studies of intravenous drip infusion of micronomicin. 1. Pharmacokinetics (Part 2). Intravenous Micronomicin Research Group]. ( Kawaguchi, Y; Koyama, M; Mitsuhashi, S; Saito, I; Watanabe, M, 1985) |
| "In gentamicin - treated patients LMWP elimination increased, especially LZM which rose markedly during treatment and returned to normal values after its end." | 1.26 | Gentamicin and sisomicin - induced renal tubular damage. ( Charmes, JP; Lachâtre, G; Merle, L; Nicot, G; Valette, JP, 1982) |
| " Under long-term administration of Gentamycin or Dextran the excretion of enzymes already reduced during therapy." | 1.26 | [Drug induced nephropathy and enzymes of renal origin in the urine]. ( Anton, D; Burchardt, U; Müller, G; Patsch, R; Schinköthe, G, 1982) |
| "Indomethacin did not inhibit the antibacterial effect of gentamycin and, administered alone, it increased the renal concentration ability." | 1.26 | Indomethacin and gentamycin treatment in experimental kidney infection. ( Farkas, E; Petheö, G; Sallai, J; Túri, S, 1982) |
| "Gentamicin sulfate was tested for nephrotoxicity in B6D2F1 hybrid mice after s." | 1.26 | [Nephrotoxicity of gentamicin in mice]. ( Walzl, HL, 1982) |
| "A retrospective and a prospective group of 38 and 20 patients respectively were studied with regard to bacterial strains, clinical effect, toxic side effects and serum concentration of gentamicin in severe surgical infections." | 1.26 | Gentamicin treatment in severe surgical infections--serum levels, interactions, toxicity and efficacy. ( Athlin, L; Domellöf, L; Holm, S, 1981) |
| " Clinical and pharmacokinetic data were obtained on 240 of 267 courses (120 courses each of gentamicin and tobramycin)." | 1.26 | Clinical and pharmacokinetic characteristics of aminoglycoside nephrotoxicity in 201 critically ill patients. ( Cerra, FB; Plaut, ME; Schentag, JJ, 1982) |
| " The dosage of gentamicin was carefully monitored by serum concentration assays." | 1.26 | Renal function of neonates during gentamicin treatment. ( Bergmark, J; Hiesche, K; Jagenburg, R; Tessin, I; Trollfors, B, 1982) |
| "Present methods for dosing gentamicin are based on usual doses or desired peak concentrations." | 1.26 | Analog computer monitoring and evaluation of a dosing nomogram for gentamicin based on the C'min-method, part II. ( Banarer, M; Diaz, D; Margary, JB; Otero, JD; Ritschel, WA, 1980) |
| "However, an eighth patient with acute renal failure caused by bacteraemic shock rapidly recovered renal function while being treated with cefuroxime and gentamicin for 15 days after large doses of frusemide intravenously." | 1.26 | The safety of cefuroxime and gentamicin in patients with reduced renal function. ( Bax, RP; Cockram, CS; Richards, P, 1980) |
| " This dosage of cefuroxime was protective when given for only two consecutive days starting on the first to third days of gentamicin treatment, but enhanced gentamicin nephrotoxocity when started on the sixth or subsequent days." | 1.26 | Effect of timing of cefuroxime dosage on its protection of rats against gentamicin nephrotoxicity. ( Atkinson, RM; Capel-Edwards, K; Foord, RD; Harman, IW; Patterson, GG; Pratt, DA; Wheeldon, JM, 1980) |
| " The relative tolerance of the neonatal puppy to the toxic effects of gentamicin was attributed to the distribution of renal blood flow predominantly to juxtamedullar nephrons at birth which spared superficial nephrons from gentamicin accumulation and toxicity until renal blood flow was redistributed to the outer cortex and filtration in superficial nephrons began after the first wk of life." | 1.26 | Pathophysiologic evidence of gentamicin nephrotoxicity in neonatal puppies. ( Arant, BS; Cowan, RH; Jukkola, AF, 1980) |
| " However, Win 42122-2 was markedly less toxic than gentamicin in subacute nephrotoxicity studies in rats, ototoxicity experiments in guinea pigs, and ataxia determinations in cats." | 1.26 | Antibacterial activities, nephrotoxicity, and ototoxicity of a new aminoglycoside, Win 42122-2. ( Came, PE; Dobson, RA; Fabian, RJ; O'Connor, JR; Wagner, RB, 1979) |
| " Pharmacokinetic studies revealed lower renal concentrations of netilmicin after repetitive administration." | 1.26 | [Netilmicin and tobramycin: comparative evaluation of pharmacokinetics, nephrotoxicity, and therapeutic efficacy in animal studies (author's transl)]. ( Abraham, M; Freiesleben, H; Marre, R; Sack, K, 1979) |
| " Differences in methods and dosage of administration depending upon age, status of renal function, and route of administration are discussed." | 1.26 | The pharmacology of newer aminoglycosides, with a consideration of the application to clinical situations. ( Neu, HC, 1977) |
| "Gentamicin was given to paediatric patients with chronic renal disease complicated by infections by Gram-negative organisms, in which renal function varied from normal to severely insufficient." | 1.26 | Dosage schedule of gentamicin for chronic renal insufficiency in children. ( Hattori, S; Matsuda, I; Takimoto, M; Yoshioka, H, 1978) |
| "3 mug/ml; 31 to 47% of the drug was excreted within the 8-h dosage interval." | 1.26 | Clinico-pharmacological studies of sisomicin in ill children. ( Dugal, R; Hammerberg, S; Marks, MI; Vose, A, 1978) |
| "The accuracy of predicting serum gentamicin levels based on a one-compartment open linear pharmacokinetic model was studied." | 1.26 | Prediction of gentamicin serum levels using a one-compartment open linear pharmacokinetic model. ( Bartlett, R; Chow, M; Deglin, J; Harralson, A; Quintiliani, R, 1978) |
| "Gentamicin therapy was reinstituted two days later, at a dosage of 5 mg/kg/day." | 1.26 | Gentamicin-cephalothin drug reaction. ( Gurwich, EL; Hoy, RH; Sula, J, 1978) |
| "Netilmicin, 2 mg/kg, was infused intravenously over 1 h." | 1.26 | Pharmacokinetics of netilmicin in patients with renal impairment and in patients on dialysis. ( Brannon, DR; Costello, RJ; Luft, FC; Maxwell, DR; Sloan, RS; Stropes, LL, 1978) |
| "Treatment with gentamicin prior to enflurane also resulted in reduced urinary osmolality compared to enflurane or gentamicin alone (GE, 742 +/- 57; E, 1709 +/- 66; G, 985 +/- 32 m0sm/kg)." | 1.26 | Enflurane nephrotoxicity and pre-existing renal dysfunction. ( Cousins, MJ; David, W; Fulton, A; Haynes, G; Whitehead, R, 1978) |
| "Tobramycin is a new aminoglycoside antibiotic with pharmacological similarities to gentamicin." | 1.26 | Tobramycin in the treatment of severe and complicated urinary tract infections. ( Bailey, RR; Peddie, B, 1976) |
| " Knowledge of serum levels of gentamicin assists the clinician in regulating drug dosage to obtain an optimal therapeutic effect, and yet avoid toxic serum levels." | 1.26 | Radioimmunoassay as an improved method for measurement of serum levels of gentamicin. ( Atkins, RC; Casley, D; Johnston, CI; Longmore, P, 1976) |
| " The predominant factors in the production of methoxyflurane nephrotoxicity appear to be high methoxyflurane dosage and serum inorganic fluoride concentration." | 1.26 | Methoxyflurane nephropathy. ( Mazze, RI, 1976) |
| " The prophylactic effect upon ototoxicity of the administration of dimercaptopropanol or of dividing up the daily dosage was examined." | 1.26 | [Ototoxicity of the aminoglycoside antibiotics (author's transl)]. ( Federspil, P, 1976) |
| " Gentamicin, at 6 to 50 mg/kg per day, caused pathological changes which were dosage related and affected primarily the proximal tubular cells." | 1.26 | Protective effect of cephalothin against gentamincin-induced nephrotoxicity in rats. ( Barza, M; Dellinger, P; Murphy, T; Pinn, V; Weinstein, L, 1976) |
| "Gentamicin sulphate was administered to male Wistar rats by intramuscular injection at varying dosage and for varying periods." | 1.26 | Renal damage caused by gentamicin: a study of the effects on renal morphology and urinary enzyme excretion. ( Lovell, D; Thompson, AE; Tighe, JR; Wellwood, JM, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 324 (50.39) | 18.7374 |
| 1990's | 94 (14.62) | 18.2507 |
| 2000's | 86 (13.37) | 29.6817 |
| 2010's | 118 (18.35) | 24.3611 |
| 2020's | 21 (3.27) | 2.80 |
| Authors | Studies |
|---|---|
| Laaroussi, H | 1 |
| Bakour, M | 1 |
| Ousaaid, D | 1 |
| Ferreira-Santos, P | 1 |
| Genisheva, Z | 1 |
| El Ghouizi, A | 1 |
| Aboulghazi, A | 1 |
| Teixeira, JA | 1 |
| Lyoussi, B | 1 |
| Becerir, T | 1 |
| Tokgün, O | 1 |
| Yuksel, S | 1 |
| Abdeen, A | 1 |
| Samir, A | 1 |
| Elkomy, A | 1 |
| Aboubaker, M | 1 |
| Habotta, OA | 1 |
| Gaber, A | 1 |
| Alsanie, WF | 1 |
| Abdullah, O | 1 |
| Elnoury, HA | 1 |
| Baioumy, B | 1 |
| Ibrahim, SF | 1 |
| Abdelkader, A | 1 |
| Abouzed, TK | 1 |
| Sherif, EAE | 1 |
| Barakat, MES | 1 |
| Sadek, KM | 1 |
| Aldhahrani, A | 1 |
| Nasr, NE | 1 |
| Eldomany, E | 1 |
| Khailo, K | 1 |
| Dorghamm, DA | 1 |
| Sridharan, K | 1 |
| Al Jufairi, M | 1 |
| Al Segai, O | 1 |
| Al Ansari, E | 1 |
| Hashem Ahmed, H | 1 |
| Husain Shaban, G | 1 |
| Malalla, Z | 1 |
| Al Marzooq, R | 1 |
| Al Madhoob, A | 1 |
| Saeed Tabbara, K | 1 |
| Laorodphun, P | 1 |
| Cherngwelling, R | 1 |
| Panya, A | 1 |
| Arjinajarn, P | 2 |
| Geshnigani, SSH | 1 |
| Mahdavinia, M | 1 |
| Kalantar, M | 2 |
| Goudarzi, M | 2 |
| Khorsandi, L | 1 |
| Kalantar, H | 1 |
| Murugan, R | 1 |
| Rajesh, R | 1 |
| Velayutham, M | 1 |
| Juliet, A | 1 |
| Gopinath, P | 1 |
| Arockiaraj, J | 1 |
| Bolten, JS | 1 |
| Tanner, C | 1 |
| Rodgers, G | 1 |
| Schulz, G | 1 |
| Levano, S | 1 |
| Weitkamp, T | 1 |
| Waldner, S | 1 |
| Puligilla, RD | 1 |
| Bodmer, D | 1 |
| Müller, B | 1 |
| Huwyler, J | 1 |
| Suhett, WG | 1 |
| Gerez, JR | 1 |
| Hohmann, MS | 1 |
| Staurengo-Ferrari, L | 1 |
| Verri, WA | 1 |
| Pinho, FHO | 1 |
| de Barros, LD | 1 |
| Cardim, ST | 1 |
| Flaiban, KMC | 1 |
| Bracarense, APFRL | 1 |
| Wang, J | 4 |
| Cheng, D | 1 |
| Zhu, L | 2 |
| Wang, P | 1 |
| Liu, HW | 1 |
| Chen, M | 1 |
| Yuan, L | 1 |
| Zhang, XB | 1 |
| Medić, B | 1 |
| Stojanović, M | 1 |
| Rovčanin, B | 1 |
| Kekić, D | 1 |
| Škodrić, SR | 1 |
| Jovanović, GB | 1 |
| Vujović, KS | 1 |
| Divac, N | 1 |
| Stojanović, R | 1 |
| Radenković, M | 2 |
| Prostran, M | 1 |
| Vaishnu Devi, D | 1 |
| Viswanathan, P | 1 |
| Abdelrahman, RS | 1 |
| Abdelmageed, ME | 1 |
| Helmy, MM | 1 |
| Mouneir, SM | 1 |
| Dvořáčková, E | 1 |
| Pávek, P | 1 |
| Kováčová, B | 1 |
| Rychlíčková, J | 1 |
| Suchopár, O | 1 |
| Hojný, M | 1 |
| Tebbens, JD | 1 |
| Vlček, J | 1 |
| Mahi-Birjand, M | 1 |
| Yaghoubi, S | 1 |
| Abdollahpour-Alitappeh, M | 1 |
| Keshtkaran, Z | 1 |
| Bagheri, N | 1 |
| Pirouzi, A | 1 |
| Khatami, M | 1 |
| Sineh Sepehr, K | 1 |
| Peymani, P | 1 |
| Karimzadeh, I | 1 |
| Kato, Y | 1 |
| Tonomura, Y | 1 |
| Hanafusa, H | 1 |
| Nishimura, K | 1 |
| Fukushima, T | 1 |
| Ueno, M | 1 |
| Elsakka, EGE | 1 |
| Elsisi, AM | 1 |
| Mansour, OAA | 1 |
| Elsadek, BEM | 1 |
| Abd Elaziz, AI | 1 |
| Salama, SA | 1 |
| Allam, S | 1 |
| Karimi, Z | 1 |
| Pakfetrat, Z | 1 |
| Roozbeh, J | 1 |
| Janfeshan, S | 1 |
| Alam, W | 1 |
| Khan, H | 1 |
| Khan, SA | 3 |
| Ali, N | 1 |
| Sharif, N | 1 |
| Ghafar, R | 1 |
| Daglia, M | 1 |
| Nazir, S | 1 |
| Rawls, KD | 1 |
| Dougherty, BV | 1 |
| Vinnakota, KC | 1 |
| Pannala, VR | 1 |
| Wallqvist, A | 1 |
| Kolling, GL | 1 |
| Papin, JA | 1 |
| Kurtzman, JT | 1 |
| Margolin, EJ | 1 |
| Li, G | 1 |
| Barone, JC | 1 |
| Aaron, JG | 1 |
| Kubin, CJ | 1 |
| Anderson, CB | 1 |
| Sharma, VC | 1 |
| Kaushik, A | 1 |
| Dey, YN | 1 |
| Srivastava, B | 1 |
| Wanjari, M | 1 |
| Pawar, S | 1 |
| Chougule, S | 1 |
| Mahmoud, AM | 1 |
| Abd El-Ghafar, OAM | 1 |
| Alzoghaibi, MA | 1 |
| Hassanein, EHM | 1 |
| Elsisi, AEE | 1 |
| Sokar, SS | 1 |
| Shalaby, MF | 1 |
| Abu-Risha, SE | 1 |
| Khattab, HA | 1 |
| Wazzan, MA | 1 |
| Al-Ahdab, MA | 1 |
| Ehsani, V | 1 |
| Amirteimoury, M | 1 |
| Taghipour, Z | 1 |
| Shamsizadeh, A | 1 |
| Bazmandegan, G | 1 |
| Rahnama, A | 1 |
| Khajehasani, F | 1 |
| Fatemi, I | 2 |
| Al-Asmari, AK | 1 |
| Abbasmanthiri, R | 1 |
| Al-Elawi, AM | 1 |
| Al-Horaib, G | 1 |
| Al-Sadoon, K | 1 |
| Al-Asmari, BA | 1 |
| Mahmoud, YI | 1 |
| Ramasamy, A | 1 |
| Jothivel, N | 1 |
| Das, S | 1 |
| Swapna, A | 1 |
| Albert, AP | 1 |
| Barnwal, P | 1 |
| Babu, D | 1 |
| Ghaznavi, H | 1 |
| Kalantari, H | 1 |
| Hosseini Tabatabaei, SMT | 1 |
| Mehrabani, M | 1 |
| Gholamine, B | 1 |
| Mehrzadi, S | 1 |
| Al Suleimani, YM | 1 |
| Abdelrahman, AM | 1 |
| Karaca, T | 1 |
| Manoj, P | 1 |
| Ashique, M | 1 |
| Nemmar, A | 2 |
| Ali, BH | 15 |
| Alimoradian, A | 1 |
| Changizi-Ashtiyani, S | 2 |
| Ghiasabadi Farahani, A | 1 |
| Kheder, L | 1 |
| Rajabi, R | 1 |
| Sharifi, A | 1 |
| Hajihashemi, S | 1 |
| Jafarian, T | 1 |
| Ahmadi, M | 1 |
| Rahbari, A | 1 |
| Ghanbari, F | 1 |
| Chowdhury, MS | 1 |
| Saha, SK | 1 |
| Eva, EO | 1 |
| Sarker, MM | 1 |
| Subramaniyan, V | 1 |
| Shaik, S | 1 |
| Bag, A | 1 |
| Manavalan, G | 1 |
| Chandiran, S | 1 |
| Helal, MG | 1 |
| Zaki, MMAF | 1 |
| Said, E | 1 |
| A, V | 1 |
| S, A | 2 |
| Kuriakose, J | 1 |
| Midhun, SJ | 1 |
| Jyothis, M | 1 |
| Latha, MS | 1 |
| Martins, ALCL | 1 |
| Watanabe, M | 3 |
| Fernandes, SM | 1 |
| Fonseca, CDD | 1 |
| Vattimo, MFF | 1 |
| Gheith, I | 1 |
| El-Mahmoudy, A | 1 |
| Friesen, WJ | 1 |
| Johnson, B | 1 |
| Sierra, J | 1 |
| Zhuo, J | 1 |
| Vazirani, P | 1 |
| Xue, X | 1 |
| Tomizawa, Y | 1 |
| Baiazitov, R | 1 |
| Morrill, C | 1 |
| Ren, H | 1 |
| Babu, S | 1 |
| Moon, YC | 1 |
| Branstrom, A | 1 |
| Mollin, A | 1 |
| Hedrick, J | 1 |
| Sheedy, J | 1 |
| Elfring, G | 1 |
| Weetall, M | 1 |
| Colacino, JM | 1 |
| Welch, EM | 1 |
| Peltz, SW | 1 |
| Falayi, OO | 1 |
| Oyagbemi, AA | 1 |
| Omobowale, TO | 1 |
| Ayodele, EA | 1 |
| Adedapo, AD | 1 |
| Yakubu, MA | 1 |
| Adedapo, AA | 1 |
| Ahmed, HI | 1 |
| Mohamed, EA | 1 |
| Mohammed, MA | 1 |
| Aboulhoda, BE | 1 |
| Mahmoud, RH | 1 |
| Celik, OY | 1 |
| Irak, K | 1 |
| Cui, J | 1 |
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| Hong, Q | 1 |
| Lin, S | 1 |
| Sun, X | 2 |
| Cai, G | 1 |
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| Mohamadi Yarijani, Z | 1 |
| Najafi, H | 3 |
| Shackebaei, D | 1 |
| Madani, SH | 1 |
| Modarresi, M | 1 |
| Jassemi, SV | 1 |
| Saleem, M | 1 |
| Javed, F | 1 |
| Asif, M | 1 |
| Baig, MK | 1 |
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| Butt, MS | 1 |
| Randhawa, MA | 1 |
| Shahid, M | 1 |
| Bae, EH | 2 |
| Kim, IJ | 2 |
| Joo, SY | 1 |
| Kim, EY | 1 |
| Choi, JS | 1 |
| Kim, CS | 1 |
| Ma, SK | 2 |
| Lee, J | 2 |
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| Li, YC | 2 |
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| Ibrahim, BM | 1 |
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| Hsu, YH | 2 |
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| Wu, MY | 1 |
| Lin, YF | 1 |
| Chen, WL | 1 |
| Cheng, TH | 1 |
| Chen, CH | 2 |
| Ahmadvand, H | 2 |
| Ghasemi Dehnoo, M | 1 |
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| Cheraghi, RA | 1 |
| Jafarey, M | 1 |
| Changizi Ashtiyani, S | 1 |
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| Engidawork, E | 2 |
| Gautier, JC | 3 |
| Gury, T | 2 |
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| Masson, R | 1 |
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| Hoffman, D | 2 |
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| Plajer, SM | 1 |
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| Filali-Ansary, A | 1 |
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| Zhang, T | 1 |
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| Li, B | 1 |
| Sepand, MR | 1 |
| Ghahremani, MH | 1 |
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| Aghsami, M | 1 |
| Rajabi, J | 1 |
| Keshavarz-Bahaghighat, H | 1 |
| Soodi, M | 1 |
| Gai, Z | 1 |
| Visentin, M | 1 |
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| Li, T | 1 |
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| Valipour, P | 2 |
| Heidarian, E | 2 |
| Khoshdel, A | 1 |
| Gholami-Arjenaki, M | 1 |
| Liu, C | 1 |
| Kang, Y | 1 |
| Zhang, H | 1 |
| Yu, H | 1 |
| Han, C | 1 |
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| Behzadfar, F | 1 |
| Jahani, D | 1 |
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| Shaki, F | 1 |
| Seddigh, A | 1 |
| Hossaini, N | 1 |
| Avan, A | 1 |
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| Nedaeinia, R | 1 |
| Pongchaidecha, A | 1 |
| Chueakula, N | 1 |
| Jaikumkao, K | 1 |
| Chatsudthipong, V | 1 |
| Mahatheeranont, S | 1 |
| Norkaew, O | 1 |
| Chattipakorn, N | 1 |
| Lungkaphin, A | 1 |
| Jose, SP | 1 |
| Im, K | 1 |
| M, R | 1 |
| Santhosh, S | 1 |
| S, S | 1 |
| B, GK | 1 |
| C, P | 1 |
| Chashmi, NA | 1 |
| Emadi, S | 1 |
| Khastar, H | 2 |
| Jafari-Dehkordi, E | 1 |
| Ghatreh-Samani, K | 1 |
| Ashrafi-Eshkaftaki, L | 1 |
| Priyamvada, S | 2 |
| Priyadarshini, M | 1 |
| Arivarasu, NA | 1 |
| Farooq, N | 2 |
| Khan, S | 1 |
| Khan, MW | 1 |
| Yusufi, AN | 2 |
| Karadeniz, A | 1 |
| Yildirim, A | 1 |
| Simsek, N | 1 |
| Kalkan, Y | 1 |
| Celebi, F | 1 |
| Nitha, B | 1 |
| Janardhanan, KK | 1 |
| McGlone, A | 1 |
| Cranswick, N | 1 |
| Bookstaver, PB | 1 |
| Johnson, JW | 1 |
| McCoy, TP | 1 |
| Stewart, D | 1 |
| Williamson, JC | 1 |
| Abdel-Raheem, IT | 2 |
| Abdel-Ghany, AA | 1 |
| Mohamed, GA | 1 |
| Nakayama, H | 1 |
| Echizen, H | 1 |
| Gomi, T | 1 |
| Shibuya, Y | 1 |
| Nakamura, Y | 1 |
| Nakano, K | 1 |
| Arashi, H | 1 |
| Itai, T | 1 |
| Ohnishi, S | 1 |
| Tanaka, M | 1 |
| Orii, T | 1 |
| Mohammadi-Karakani, A | 1 |
| Asgharzadeh-Haghighi, S | 1 |
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| Dettli, L | 1 |
| Bartunek, J | 1 |
| Kraft, D | 1 |
| Mayer-Hausner, E | 1 |
| Lumholtz, B | 1 |
| Kampmann, TJ | 1 |
| Siersbaek-Nielsen, K | 1 |
| Hansen, JM | 1 |
| Dubois, D | 1 |
| Robert, M | 1 |
| Hautmann, R | 2 |
| Nielsen, AB | 1 |
| Elb, S | 1 |
| Woodroffe, AJ | 1 |
| Thomson, NM | 1 |
| Meadows, R | 1 |
| Lawrence, JR | 1 |
| Banck, G | 3 |
| Belfrage, S | 3 |
| Toremalm, NG | 3 |
| Lagrue, G | 1 |
| Fournier, A | 1 |
| Hall, DR | 1 |
| McGibbon, DH | 1 |
| Evans, CC | 1 |
| Meadows, GA | 1 |
| Nachbur, B | 1 |
| Lebek, G | 1 |
| Meyer, RP | 1 |
| Neiger, M | 1 |
| Nyffegger, R | 1 |
| Brentano, M | 1 |
| Blumer, R | 1 |
| Stille, W | 2 |
| Klastersky, J | 1 |
| Milner, RD | 1 |
| Ross, J | 1 |
| Froud, DJ | 1 |
| Davis, JA | 1 |
| Jacobsen, S | 1 |
| Wieck, HH | 1 |
| Ulrich, G | 1 |
| Barr, GA | 1 |
| Kosek, JC | 1 |
| Rosaschino, F | 1 |
| Carnelli, V | 1 |
| Bosco, U | 1 |
| Eknoyan, G | 1 |
| Hansten, PD | 1 |
| Morse, FP | 1 |
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| Lockwood, WR | 1 |
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| Kurth, M | 1 |
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| Lutzeyer, W | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pharmacokinetics of Tobramycin Administered at the Beginning of Intermittent Hemodialysis Session[NCT03904836] | Phase 1 | 11 participants (Actual) | Interventional | 2019-01-31 | Completed | ||
| Treatment of Febrile Infectious Disease Among Children in Hadera District Given the Final Diagnosis. Descriptive Study[NCT02313532] | 500 participants (Anticipated) | Observational | 2015-01-31 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
34 reviews available for gentamicin and Kidney Diseases
| Article | Year |
|---|---|
Protective effects of pharmacological agents against aminoglycoside-induced nephrotoxicity: A systematic review.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Gentamicins; Humans; Kidney Diseases; Protective Ag | 2020 |
Aminoglycoside-induced nephrotoxicity.
Topics: Amikacin; Anti-Bacterial Agents; Gentamicins; Humans; Kidney Diseases; Tobramycin | 2014 |
Risk of gentamicin toxicity in neonates treated for possible severe bacterial infection in low- and middle-income countries: Systematic Review.
Topics: Anti-Bacterial Agents; Bacterial Infections; Developing Countries; Ear Diseases; Gentamicins; Humans | 2015 |
Evidence behind the WHO guidelines: Hospital care for children: what is the evidence of safety of gentamicin use in children?
Topics: Anti-Bacterial Agents; Bacterial Infections; Child; Developing Countries; Evidence-Based Medicine; E | 2008 |
Amelioration of aminoglycoside nephrotoxicity requires protection of renal mitochondria.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Cell Death; Gentamicins; Hypoglycemic Agents; Kidne | 2010 |
New insights into the mechanism of aminoglycoside nephrotoxicity: an integrative point of view.
Topics: Aminoglycosides; Anti-Bacterial Agents; Gentamicins; Humans; Kidney Diseases; Kidney Glomerulus; Kid | 2011 |
Experimental gentamicin nephrotoxicity and agents that modify it: a mini-review of recent research.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Apoptosis; Disease Models, Animal; Drug Interactions; | 2011 |
[Carnosine, carnosinase and kidney diseases].
Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Carnosine; Diabetic N | 2012 |
Agents ameliorating or augmenting experimental gentamicin nephrotoxicity: some recent research.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Calcium; Drug Synergism; Gentamicins; Humans; Kidney D | 2003 |
Proteomics and nephrotoxicity.
Topics: Drug-Related Side Effects and Adverse Reactions; Electrophoresis, Gel, Two-Dimensional; Gentamicins; | 2004 |
One dose per day compared to multiple doses per day of gentamicin for treatment of suspected or proven sepsis in neonates.
Topics: Anti-Bacterial Agents; Drug Administration Schedule; Ear Diseases; Gentamicins; Humans; Infant, Newb | 2006 |
Protein biomarkers of nephrotoxicity; a review and findings with cyclosporin A, a signal transduction kinase inhibitor and N-phenylanthranilic acid.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Biom | 2005 |
Glomerular nephrotoxicity of aminoglycosides.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Apoptosis; Gentamicins; Glomerular Filtration Rate; | 2007 |
Renoprotection by pituitary adenylate cyclase-activating polypeptide in multiple myeloma and other kidney diseases.
Topics: Animals; Gentamicins; Humans; Kidney Diseases; Multiple Myeloma; Pituitary Adenylate Cyclase-Activat | 2008 |
Aminoglycoside nephrotoxicity.
Topics: Aminoglycosides; Animals; Biological Transport; Calcium; Drug Resistance; Female; Gentamicins; Half- | 1983 |
Sisomicin, netilmicin and dibekacin. A review of their antibacterial activity and therapeutic use.
Topics: Aging; Animals; Bacterial Infections; Dibekacin; Drug Interactions; Drug Resistance, Microbial; Drug | 1984 |
[Aminoglycoside nephrotoxicity. III. Changes in subcellular elements].
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Gentamicins; Humans; Kidney Diseases; Lysosomes; Mi | 1980 |
Nephrotoxicity of vancomycin and aminoglycoside therapy separately and in combination.
Topics: Aged; Aged, 80 and over; Amikacin; Drug Therapy, Combination; Female; Gentamicins; Humans; Kidney Di | 1993 |
An overview of the safety of isepamicin in adults.
Topics: Adult; Aged; Anti-Bacterial Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III a | 1995 |
[Drug-induced nephrotoxicity].
Topics: Amidinotransferases; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Calcium; Cell | 1996 |
Effectiveness and safety of once-daily aminoglycosides: a meta-analysis.
Topics: Adult; Aged; Amikacin; Anti-Bacterial Agents; Controlled Clinical Trials as Topic; Drug Administrati | 1996 |
Gentamicin in 1978.
Topics: Amikacin; Animals; Bacterial Infections; Drug Synergism; Ear Diseases; Gentamicins; Humans; Kidney; | 1978 |
[Antibiotic-induced diseases. Aminoglycoside-induced renal lesions].
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Bacterial Infections; Drug Synergism; Dru | 1978 |
Aminoglycoside nephrotoxicity: pathogenesis and prevention.
Topics: Acute Kidney Injury; Aminoglycosides; Gentamicins; Glomerular Filtration Rate; Humans; Kidney; Kidne | 1979 |
Aminoglycoside renal cortical kinetics: a clue to mechanisms of nephrotoxicity.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Gentamicins; Humans; Kidney Cortex; Kidney Diseases | 1979 |
Antibiotic nephrotoxicity. A review of pathogenesis and prevention.
Topics: Acute Kidney Injury; Aminoglycosides; Animals; Anti-Bacterial Agents; Antifungal Agents; Cephalospor | 1975 |
Clinical pharmacokinetics, toxicity and cost effectiveness analysis of aminoglycosides and aminoglycoside dosing services.
Topics: Amikacin; Aminoglycosides; Cost-Benefit Analysis; Ear Diseases; Gentamicins; Humans; Kidney Diseases | 1987 |
Cyclosporine nephrotoxicity.
Topics: Animals; Blood Pressure; Cyclosporins; Disease Models, Animal; Gentamicins; Glomerular Filtration Ra | 1986 |
Cyclosporine: toxicity, metabolism, and drug interactions--implications from animal studies.
Topics: Animals; Cyclosporins; Disease Models, Animal; Dogs; Drug Interactions; Gentamicins; Humans; Ketocon | 1985 |
[Side effects of antibiotics-aminoglycosides].
Topics: Age Factors; Aged; Animals; Anti-Bacterial Agents; Deafness; Drug Resistance, Microbial; Ear Disease | 1972 |
Antibiotics and the kidney.
Topics: Amphotericin B; Anti-Bacterial Agents; Cephalosporins; Gentamicins; Humans; Kanamycin; Kidney; Kidne | 1973 |
Adverse effects of antibiotics.
Topics: Aminoglycosides; Ampicillin; Anemia, Hemolytic, Autoimmune; Anti-Bacterial Agents; Carbenicillin; Ce | 1972 |
Cardiocirculatory adaptation to chronic hypoxia. 3. Comparative study of cardiac output, pulmonary and systemic circulation between sea level and high altitude residents.
Topics: Bacterial Infections; Carbenicillin; Drug Stability; Drug Synergism; Escherichia coli; Gentamicins; | 1972 |
[Significant side effects of antibiotics].
Topics: Adolescent; Adult; Aged; Animals; Anti-Bacterial Agents; Cephalosporins; Child; Child, Preschool; Ch | 1971 |
45 trials available for gentamicin and Kidney Diseases
| Article | Year |
|---|---|
Calcium dobesilate for prevention of gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Blood Urea Nitrogen; Calcium Dobesilate; Creatinine; Disease Models, Animal; Ferric Compoun | 2014 |
Intra-articular implantation of gentamicin impregnated collagen sponge causes joint inflammation and impaired renal function in dogs.
Topics: Absorbable Implants; Animals; Anti-Bacterial Agents; Arthritis, Experimental; Cartilage, Articular; | 2016 |
A prospective comparative study of gentamicin- and amikacin-induced nephrotoxicity in patients with normal baseline renal function.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Creatinine; Dose-Respon | 2009 |
Pharmacokinetic dosing of aminoglycosides: a controlled trial.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Creatinine; Dose-Respon | 2003 |
Treatment of urinary tract infection with gentamicin once or three times daily.
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Drug Administration Schedule; Ear Diseas | 2003 |
Effect of silymarin and vitamin E on gentamicin-induced nephrotoxicity in dogs.
Topics: Animals; Anti-Bacterial Agents; Blood Urea Nitrogen; Creatinine; Dog Diseases; Dogs; Drug Therapy, C | 2007 |
Ceftriaxone versus combined gentamicin and clindamycin for polymicrobial surgical sepsis.
Topics: Abdomen; Abscess; Adolescent; Adult; Aged; Bacterial Infections; Cefotaxime; Ceftriaxone; Clindamyci | 1984 |
Third-generation cephalosporins for polymicrobial surgical sepsis.
Topics: Abscess; Adolescent; Adult; Aged; Bacteria; Bacterial Infections; Cefoperazone; Cefotaxime; Cephalos | 1983 |
Efficacy of amdinocillin and lack of nephrotoxicity when combined with a second beta-lactam antibiotic for therapy of serious gram-negative bacillary infections.
Topics: Adult; Aged; Amdinocillin; Anti-Bacterial Agents; Drug Therapy, Combination; Enterobacteriaceae Infe | 1983 |
Risk factors for nephrotoxicity in patients treated with aminoglycosides.
Topics: Aged; Aminoglycosides; Analysis of Variance; Anti-Bacterial Agents; Clinical Trials as Topic; Double | 1984 |
Netilmicin in the treatment of immunocompromised patients.
Topics: Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Clinical Trials as Topic; Drug Therapy | 1984 |
Prospective randomized double-blind comparison of nephrotoxicity and auditory toxicity of tobramycin and netilmicin.
Topics: Adult; Aged; Auditory Threshold; Clinical Trials as Topic; Creatinine; Double-Blind Method; Female; | 1984 |
Comparative cost effectiveness of gentamicin and tobramycin.
Topics: Adult; Bacterial Infections; Clinical Trials as Topic; Cost-Benefit Analysis; Double-Blind Method; G | 1984 |
Evaluation of urinary elimination of N-acetyl-beta-glucosaminidase in healthy volunteers treated with dibekacin or gentamicin.
Topics: Acetylglucosaminidase; Adult; Dibekacin; Gentamicins; Hexosaminidases; Humans; Kanamycin; Kidney Dis | 1982 |
Multicenter comparative evaluation of netilmicin and gentamicin in adult patients. Efficacy and safety.
Topics: Adolescent; Adult; Bacterial Infections; Female; Gentamicins; Hearing Disorders; Humans; Kidney Dise | 1981 |
Comparative toxicity of gentamicin versus tobramycin: a randomized prospective study.
Topics: Anti-Bacterial Agents; Bacterial Infections; Drug Resistance, Microbial; Gentamicins; Hearing Disord | 1981 |
Once-daily gentamicin versus once-daily netilmicin in patients with serious infections--a randomized clinical trial.
Topics: Aged; Bacterial Infections; Creatinine; Female; Gentamicins; Hearing Disorders; Humans; Injections, | 1994 |
Once-daily aminoglycoside dosing.
Topics: Drug Administration Schedule; Ear Diseases; Gentamicins; Humans; Infections; Kidney Diseases; Prospe | 1993 |
An overview of the safety of isepamicin in adults.
Topics: Adult; Aged; Anti-Bacterial Agents; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III a | 1995 |
Validation and nephrotoxicity of a simplified once-daily aminoglycoside dosing schedule and guidelines for monitoring therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Female; Gentamicins; Humans; Kidn | 1996 |
Evaluation of gentamicin-induced nephrotoxicosis in toadfish.
Topics: Animals; Anti-Bacterial Agents; Female; Fish Diseases; Fishes; Gentamicins; Injections, Intramuscula | 1996 |
Effect of aminoglycoside therapy on renal function in full-term infants.
Topics: Amikacin; Anti-Bacterial Agents; Gentamicins; Humans; Infant, Newborn; Kidney Diseases; Kidney Funct | 1996 |
Safety of intravenous bolus administration of gentamicin in pediatric patients.
Topics: Adolescent; Anti-Bacterial Agents; Blood Urea Nitrogen; Child; Child, Preschool; Creatinine; Female; | 2001 |
Gentamicin in neonatal infection: once versus twice daily dosage.
Topics: Age Factors; Anti-Bacterial Agents; Bacterial Infections; Body Weight; Creatinine; Drug Administrati | 2001 |
Nephrotoxicity induced by gentamicin and amikacin.
Topics: Adult; Aged; Amikacin; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Meth | 1978 |
Netilmicin treatment of complicated urinary tract infection in patients with renal function impairment.
Topics: Aged; Blood Urea Nitrogen; Clinical Trials as Topic; Creatinine; Gentamicins; Humans; Kidney Disease | 1979 |
Sisomicin in the treatment of urinary tract infections.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Clinical Trials as Topic; Female; Gentamicins; Humans | 1979 |
Relationship between aminoglycoside-induced nephrotoxicity and auditory toxicity.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Cephalothin; Drug Therapy, Combination; Gentamicin | 1979 |
Prospective comparative evaluation of gentamicin or gentamicin plus cephalothin in the production of nephrotoxicity in man.
Topics: Adult; Aged; Bacterial Infections; Cephalothin; Creatinine; Drug Synergism; Drug Therapy, Combinatio | 1979 |
Comparative efficacy and toxicity of amikacin/carbenicillin versus gentamicin/carbenicillin in leukopenic patients: a randomized prospective trail.
Topics: Adult; Amikacin; Bacterial Infections; Carbenicillin; Drug Synergism; Gentamicins; Hearing Disorders | 1977 |
Prospective comparative study of variable dosage and variable frequency regimens for administration of gentamicin.
Topics: Clinical Trials as Topic; Drug Administration Schedule; Gentamicins; Humans; Injections, Intramuscul | 1975 |
Gentamicin blood levels: a guide to nephrotoxicity.
Topics: Creatinine; Gentamicins; Humans; Kidney Diseases; Methods; Time Factors | 1975 |
Does administration of an aminoglycoside in a single daily dose affect its efficacy and toxicity?
Topics: Audiometry; Bacterial Infections; Creatinine; Edetic Acid; Electronystagmography; Gentamicins; Heari | 1990 |
The absence of nephrotoxicity and differential nephrotoxicity between tobramycin and gentamicin.
Topics: Acetylglucosaminidase; Adult; Aged; beta 2-Microglobulin; Creatine; Double-Blind Method; Drug Admini | 1990 |
Multicenter comparative study of aztreonam and gentamicin in the treatment of renal and urinary tract infections.
Topics: Adult; Aged; Ambulatory Care; Aztreonam; Bacterial Infections; Female; Gentamicins; Humans; Injectio | 1989 |
A controlled study of the nephrotoxicity of mezlocillin and gentamicin plus ampicillin in the neonate.
Topics: Ampicillin; Bacterial Infections; Clinical Trials as Topic; Drug Therapy, Combination; Gentamicins; | 1987 |
Is tobramycin less nephrotoxic than gentamicin?
Topics: Clinical Trials as Topic; Creatinine; Double-Blind Method; Gentamicins; Humans; Kidney Diseases; Ran | 1986 |
[Which factors are increasing the nephrotoxicity of aminoglucoside antibiotics?].
Topics: Anti-Bacterial Agents; Clinical Trials as Topic; Drug Evaluation; Gentamicins; Humans; Kidney; Kidne | 1986 |
Review of amikacin usage in the EORTC trials.
Topics: Agranulocytosis; Amikacin; Anti-Bacterial Agents; Bacterial Infections; Clinical Trials as Topic; Dr | 1985 |
Prospective, randomized comparison of the efficacy and safety of netilmicin-clindamycin and tobramycin-clindamycin in the treatment of serious systemic infections.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Clindamycin; Drug Combinations; Female; Gentamicins; | 1985 |
Gentamicin and kanamycin in the treatment of gram-negative sepsis: a comparative study.
Topics: Bacterial Infections; Body Temperature; Drug Synergism; Gentamicins; Humans; Kanamycin; Kidney Disea | 1971 |
[Clinical study of high doses of gentamicin on oto- and nephrotoxicity in man].
Topics: Adolescent; Adult; Audiometry; Child; Clinical Trials as Topic; Gentamicins; Hearing Disorders; Huma | 1973 |
[Indications and dangers of combined cephalothin-gentamicin therapy].
Topics: Aged; Bacterial Infections; Cephalothin; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Com | 1974 |
[Postoperative gentamycin therapy. Serum levels depending on dosage and temporary kidney dysfunction].
Topics: Adolescent; Adult; Audiometry; Creatinine; Female; Gentamicins; Hearing Disorders; Humans; Kidney Di | 1972 |
Therapy with gentamicin for bacteremic infections: results with 53 patients.
Topics: Bacterial Infections; Drug Synergism; Endocarditis, Bacterial; Female; Gentamicins; Humans; Infectio | 1971 |
565 other studies available for gentamicin and Kidney Diseases
| Article | Year |
|---|---|
Protective Effect of Honey and Propolis against Gentamicin-Induced Oxidative Stress and Hepatorenal Damages.
Topics: Animals; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Gentamicins; Honey; Kidney; | 2021 |
The therapeutic effect of Cilastatin on drug-induced nephrotoxicity: a new perspective.
Topics: Apoptosis; Cell Line; Cell Survival; Cilastatin; Cisplatin; Dose-Response Relationship, Drug; Gentam | 2021 |
The potential antioxidant bioactivity of date palm fruit against gentamicin-mediated hepato-renal injury in male albino rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Chemical and Drug Induced Liver Injury; | 2021 |
Assessment of gentamicin and cisplatin-induced kidney damage mediated via necrotic and apoptosis genes in albino rats.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Biomar | 2021 |
Biomarkers in neonates receiving potential nephrotoxic drugs.
Topics: Acetaminophen; Adult; Amikacin; Biomarkers; Cystatins; Female; Furosemide; Gentamicins; Hepatitis A | 2021 |
Curcumin protects rats against gentamicin-induced nephrotoxicity by amelioration of oxidative stress, endoplasmic reticulum stress and apoptosis.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Apoptosis; Creatinine; Curcumin; Dose-Response Relatio | 2022 |
Diosmin prophylaxis reduces gentamicin-induced kidney damage in rats.
Topics: Animals; Catalase; Creatinine; Diosmin; Gentamicins; Glutathione; Glutathione Peroxidase; Kidney; Ki | 2023 |
Deacetyl epoxyazadiradione protects aminoglycoside antibiotic-induced renal cell apoptosis, in vitro.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Apoptosis; Dogs; Gentamicins; Humans; Kidney; Kidney D | 2023 |
Zebrafish (Danio rerio) larvae as a predictive model to study gentamicin-induced structural alterations of the kidney.
Topics: Animals; Gentamicins; Humans; Kidney; Kidney Diseases; Kidney Glomerulus; Larva; Mammals; Mice; Zebr | 2023 |
Exploring porcine kidney explants as a model for the study of nephrotoxins and the therapeutic potential of phytic acid.
Topics: Animals; Antioxidants; Creatinine; Gentamicins; Kidney; Kidney Diseases; Oxidative Stress; Phytic Ac | 2023 |
Engineering dithiobenzoic acid lactone-decorated Si-rhodamine as a highly selective near-infrared HOCl fluorescent probe for imaging drug-induced acute nephrotoxicity.
Topics: Animals; Cell Line; Drug Design; Fluorescence; Fluorescent Dyes; Gentamicins; Humans; Hypochlorous A | 2019 |
Pioglitazone attenuates kidney injury in an experimental model of gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Anti-Bacterial Agents; Catalase; Creatinine; Gentamicins; Hypoglycemic Agents; Kidney; Kidn | 2019 |
Sulphated polysaccharide from Sargassum myriocystum confers protection against gentamicin-induced nephrotoxicity in adult zebrafish.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antioxidants; Gentamicins; Interleukin-6; | 2019 |
Renoprotective effect of celecoxib against gentamicin-induced nephrotoxicity through suppressing NFκB and caspase-3 signaling pathways in rats.
Topics: Animals; Antioxidants; Apoptosis; Blood Urea Nitrogen; Caspase 3; Celecoxib; Creatinine; Cyclooxygen | 2020 |
Reno-protective effect of linagliptin against gentamycin nephrotoxicity in rats.
Topics: Adamantane; Animals; Dipeptides; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease | 2019 |
Is computer-assisted aminoglycoside dosing managed by a pharmacist a safety tool of pharmacotherapy?
Topics: Aged; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Costs and Cost Analysis; Drug Dosage Calcula | 2019 |
Adult Zebrafish Model for Screening Drug-Induced Kidney Injury.
Topics: Activating Transcription Factor 3; Animals; Cisplatin; Early Growth Response Protein 1; Feasibility | 2020 |
Androgen/androgen receptor affects gentamicin-induced nephrotoxicity through regulation of megalin expression.
Topics: Androgens; Animals; Anti-Bacterial Agents; Flutamide; Gentamicins; Kidney Diseases; Low Density Lipo | 2020 |
Toll-like receptor-2 mediates systemic inflammation in gentamicin-induced rat nephrotoxicity.
Topics: Animals; Cytokines; Disease Models, Animal; Gentamicins; Inflammation; Inflammation Mediators; Kidne | 2020 |
Nephroprotective effects of Datura metel extract in gentamicin induced mice model: biochemical and histological evidences.
Topics: Animals; Blood Urea Nitrogen; Creatinine; Datura metel; Disease Models, Animal; Female; Gentamicins; | 2020 |
Predicting changes in renal metabolism after compound exposure with a genome-scale metabolic model.
Topics: Acetaminophen; Animals; Cells, Cultured; Databases, Genetic; Energy Metabolism; Epithelial Cells; Fe | 2021 |
Guideline-Discordant Preoperative Gentamicin Dosing and the Risk of Gentamicin Associated Nephrotoxicity in Urologic Surgery.
Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Drug Dosage Calculations; Female; Gentamicins; | 2021 |
Nephroprotective potential of Anogeissus latifolia Roxb. (Dhava) against gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Biomarkers; Combretaceae; Gene Expression Regulation; Gentamicins; Inflammation; Interleuki | 2021 |
Agomelatine prevents gentamicin nephrotoxicity by attenuating oxidative stress and TLR-4 signaling, and upregulating PPARγ and SIRT1.
Topics: Acetamides; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Gentamicins; Kidney Diseases; | 2021 |
Nephroprotective effects of febuxostat and/or mirtazapine against gentamicin-induced nephrotoxicity through modulation of ERK 1/2, NF-κB and MCP1.
Topics: Animals; Anti-Bacterial Agents; Antidepressive Agents; Chemokine CCL2; Drug Synergism; Febuxostat; G | 2021 |
Nephroprotective potential of artichoke leaves extract against gentamicin in rats: Antioxidant mechanisms.
Topics: Animals; Antioxidants; Cynara scolymus; Dose-Response Relationship, Drug; Gentamicins; Kidney Diseas | 2016 |
Protective effect of hydroalcoholic extract of Pistacia vera against gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Blood Urea Nitrogen; Creatinine; Gentamicins; Human | 2017 |
Effect of camel milk against renal toxicity in experimental rats.
Topics: Animals; Blood Glucose; Camelus; Creatinine; Gentamicins; Kidney Diseases; Kidney Glomerulus; Kidney | 2017 |
Kiwi fruit (Actinidia deliciosa) ameliorates gentamicin-induced nephrotoxicity in albino mice via the activation of Nrf2 and the inhibition of NF-κB (Kiwi & gentamicin-induced nephrotoxicity).
Topics: Actinidia; Animals; Anti-Bacterial Agents; Fruit and Vegetable Juices; Gentamicins; Kidney; Kidney D | 2017 |
Evaluation of the Protective Role of Glycine max Seed Extract (Soybean Oil) in Drug-Induced Nephrotoxicity in Experimental Rats.
Topics: Animals; Antioxidants; Biomarkers; Gentamicins; Kidney; Kidney Diseases; Kidney Function Tests; Male | 2018 |
Ameliorative effects of gallic acid on gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Blood Urea Nitrogen; Creatinine; Gallic Acid; Gentamicins; Kidney Diseases; Male; Malondial | 2018 |
The effect of the dipeptidyl peptidase-4 inhibitor sitagliptin on gentamicin nephrotoxicity in mice.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Creatinine; Cystatin C; Cytokines; Dipeptidyl- | 2018 |
Protective Effects of Pomegranate Juice on Nephrotoxicity Induced by Captopril and Gentamicin in Rats.
Topics: Animals; Biomarkers; Captopril; Cytoprotection; Disease Models, Animal; Fruit and Vegetable Juices; | 2017 |
Ameliorative Effects of Zataria Multiflora Hydro-Alcoholic extract on Gentamicin Induced Nephrotoxicity in Rats.
Topics: Animals; Blood Urea Nitrogen; Creatinine; Gentamicins; Kidney; Kidney Diseases; Lamiaceae; Lipid Per | 2018 |
A study on the Effect of Captopril on Gentamicin Induced Nephrotoxicity in Rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Bacterial Agents; Bangladesh; Captopril; Cre | 2018 |
Potential action of Rumex vesicarius (L.) against potassium dichromate and gentamicin induced nephrotoxicity in experimental rats.
Topics: Animals; Body Weight; Creatinine; Female; Gentamicins; Kidney; Kidney Diseases; Male; Organ Size; Pl | 2018 |
Nephroprotective effect of saxagliptin against gentamicin-induced nephrotoxicity, emphasis on anti-oxidant, anti-inflammatory and anti-apoptic effects.
Topics: Adamantane; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Dipep | 2018 |
Protective effect of Rotula aquatica Lour against gentamicin induced oxidative stress and nephrotoxicity in Wistar rats.
Topics: Animals; Antioxidants; Biomarkers; Boraginaceae; Cytoprotection; Disease Models, Animal; Enzymes; Fe | 2018 |
Diabetes Mellitus: a risk factor for drug toxicity.
Topics: Animals; Anti-Bacterial Agents; Diabetes Mellitus, Experimental; Gentamicins; Kidney Diseases; Kidne | 2018 |
Novel and classical renal biomarkers as evidence for the nephroprotective effect of
Topics: Animals; Antioxidants; Biomarkers; Carica; Cell Adhesion Molecules; Clusterin; Gentamicins; Humans; | 2018 |
The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential.
Topics: Aminoglycosides; Animals; Antibiotics, Antineoplastic; Cells, Cultured; Codon, Nonsense; Codon, Term | 2018 |
Nephroprotective properties of the methanol stem extract of Abrus precatorius on gentamicin-induced renal damage in rats.
Topics: Abrus; Animals; Creatinine; Gentamicins; Glutathione; Humans; Kidney Diseases; Male; Oxidative Stres | 2018 |
Candesartan and epigallocatechin-3-gallate ameliorate gentamicin-induced renal damage in rats through p38-MAPK and NF-κB pathways.
Topics: Animals; Benzimidazoles; Biphenyl Compounds; Caspase 3; Catechin; Drug Therapy, Combination; Gene Ex | 2019 |
Vitamin D attenuates gentamicin-induced acute renal damage via prevention of oxidative stress and DNA damage.
Topics: Animals; Anti-Bacterial Agents; Creatinine; DNA Damage; Gentamicins; Glutathione Peroxidase; Kidney; | 2019 |
Protective effect of date extract on rat nephrotoxicity induced by gentamicin, clinical, histological and antioxidant evidences.
Topics: Animals; Antioxidants; Gentamicins; Kidney Diseases; Oxidants; Phenols; Phoeniceae; Plant Extracts; | 2018 |
N-Acetylcysteine Ameliorates Gentamicin-Induced Nephrotoxicity by Enhancing Autophagy and Reducing Oxidative Damage in Miniature Pigs.
Topics: Acetylcysteine; Animals; Autophagy; Gene Expression Regulation; Gentamicins; Kidney; Kidney Diseases | 2019 |
Amelioration of renal and hepatic function, oxidative stress, inflammation and histopathologic damages by Malva sylvestris extract in gentamicin induced renal toxicity.
Topics: Animals; Dose-Response Relationship, Drug; Gentamicins; Inflammation; Kidney; Kidney Diseases; Kidne | 2019 |
HPLC Analysis and In Vivo Renoprotective Evaluation of Hydroalcoholic Extract of Cucumis melo Seeds in Gentamicin-Induced Renal Damage.
Topics: Analysis of Variance; Animals; Antioxidants; Body Weight; Chromatography, High Pressure Liquid; Crea | 2019 |
Nephroprotective effects of red beetroot-based beverages against gentamicin-induced renal stress.
Topics: Animals; Beta vulgaris; Creatinine; Fruit and Vegetable Juices; Gentamicins; Glutathione; Humans; Ki | 2019 |
Renoprotective effects of the direct renin inhibitor aliskiren on gentamicin-induced nephrotoxicity in rats.
Topics: Amides; Animals; Apoptosis; bcl-2-Associated X Protein; Cell Adhesion Molecules; Cytokines; Extracel | 2014 |
Gentamicin caused renal injury deeply related to methylglyoxal and N(ɛ)-(carboxyethyl)lysine (CEL).
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Gentamicins; Glutathione; Immunohistochemistry; Kidney | 2013 |
Histone deacetylase inhibitor, sodium butyrate, attenuates gentamicin-induced nephrotoxicity by increasing prohibitin protein expression in rats.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Blotting, Western; Butyrates; Dose-Response Relationsh | 2013 |
Activation of renal haeme oxygenase-1 alleviates gentamicin-induced acute nephrotoxicity in rats.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Caspase 3; Creatinine; Gentamicins; Heme Oxygenase-1; | 2013 |
Antioxidant status in rat kidneys after coexposure to uranium and gentamicin.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Drug Therapy, Combination; Gene Expression Regulation, | 2014 |
A biochemical and histopathologic study showing protection and treatment of gentamicin-induced nephrotoxicity in rabbits using vitamin C.
Topics: Animals; Antioxidants; Ascorbic Acid; Blood Urea Nitrogen; Creatinine; Gentamicins; Kidney; Kidney D | 2012 |
Effects of pentoxifylline on gentamicin-induced nephrotoxicity.
Topics: Animals; Anti-Bacterial Agents; Drug Evaluation, Preclinical; Female; Free Radical Scavengers; Genta | 2013 |
Attenuation of gentamycin-induced nephrotoxicity in rats by dietary inclusion of ginger (Zingiber officinale) and turmeric (Curcuma longa) rhizomes.
Topics: Animal Feed; Animals; Anti-Bacterial Agents; Antioxidants; Blood Urea Nitrogen; Curcuma; Diet; Dose- | 2012 |
Protective effect of selected calcium channel blockers and prednisolone, a phospholipase-A2 inhibitor, against gentamicin and carbon tetrachloride-induced nephrotoxicity.
Topics: Animals; Antioxidants; Biomarkers; Calcium Channel Blockers; Carbon Tetrachloride; Cytoprotection; D | 2014 |
Protective effects of Zhibai Dihuang Wan on renal tubular cells affected with gentamicin-induced apoptosis.
Topics: Animals; Apoptosis; Cell Line; Cell Proliferation; Drugs, Chinese Herbal; Gene Expression Regulation | 2014 |
Serum paraoxonase 1 status and its association with atherogenic indexes in gentamicin-induced nephrotoxicity in rats treated with coenzyme Q10.
Topics: Animals; Aryldialkylphosphatase; Cholesterol; Cholesterol, LDL; Cholesterol, VLDL; Gentamicins; Kidn | 2014 |
Urinary biomarkers in assessing the nephrotoxic potential of gentamicin in solitary kidney patients after 7 days of therapy.
Topics: Acetylglucosaminidase; Adult; Alpha-Globulins; Anti-Bacterial Agents; Biomarkers; Female; Gentamicin | 2014 |
Subacute administration of crude khat (Catha edulis F.) extract induces mild to moderate nephrotoxicity in rats.
Topics: Animals; Antioxidants; Catalase; Catha; Creatinine; Drug Synergism; Female; Gentamicins; Kidney; Kid | 2014 |
Comparison between male and female Sprague-Dawley rats in the response of urinary biomarkers to injury induced by gentamicin.
Topics: Animals; beta 2-Microglobulin; Biomarkers; Dose-Response Relationship, Drug; Female; Gentamicins; Ki | 2014 |
Gentamicin and renal function: lessons from 15 years' experience of a pharmacokinetic service for extended interval dosing of gentamicin.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Creatinine; Databases, Factual; D | 2015 |
Local gentamicin delivery from resorbable viscous hydrogels is therapeutically effective.
Topics: Absorbable Implants; Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Blood Urea Nitrog | 2015 |
A comparison between the nephrotoxic profile of gentamicin and gentamicin nanoparticles in mice.
Topics: Animals; Anti-Bacterial Agents; Creatinine; Gentamicins; Kidney Diseases; Kidney Tubules, Proximal; | 2015 |
β-sitosterol protects against carbon tetrachloride hepatotoxicity but not gentamicin nephrotoxicity in rats via the induction of mitochondrial glutathione redox cycling.
Topics: Animals; Antioxidants; Biological Availability; Carbon Tetrachloride; Chemical and Drug Induced Live | 2014 |
Beetroot (Beta vulgaris L.) extract ameliorates gentamicin-induced nephrotoxicity associated oxidative stress, inflammation, and apoptosis in rodent model.
Topics: Animals; Apoptosis; Arab World; Beta vulgaris; Catalase; Cytokines; Disease Models, Animal; Female; | 2014 |
Rutin attenuates gentamicin-induced renal damage by reducing oxidative stress, inflammation, apoptosis, and autophagy in rats.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Autophagy; Disease Models, Animal; Genta | 2015 |
Chitosan Prevents Gentamicin-Induced Nephrotoxicity via a Carbonyl Stress-Dependent Pathway.
Topics: Animals; Blood Urea Nitrogen; Chitosan; Gentamicins; Humans; Kidney; Kidney Diseases; Metabolic Netw | 2015 |
Protective effect of allicin against gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Antioxidants; Disulfides; Gene Expression Regulation; Gentamicins; Kidney; Kidney Diseases; | 2015 |
Gentamicin-induced ototoxicity and nephrotoxicity vary with circadian time of treatment and entail separate mechanisms.
Topics: Acetylglucosaminidase; Animals; Anti-Bacterial Agents; Auditory Threshold; Biomarkers; Brain Stem; C | 2015 |
Agmatine improves renal function in gentamicin-induced nephrotoxicity in rats.
Topics: Agmatine; Animals; Antioxidants; Creatinine; Gentamicins; Kidney; Kidney Diseases; Kidney Function T | 2016 |
Morphological and morphometric study of protective effect of green tea in gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Catalase; Female; Gentamicins; Kidney; Kidney Diseases | 2016 |
Protective effect of the methanolic leaf extract of Eclipta alba (L.) Hassk. (Asteraceae) against gentamicin-induced nephrotoxicity in Sprague Dawley rats.
Topics: Animals; Anti-Bacterial Agents; Blood Urea Nitrogen; Catalase; Creatinine; Eclipta; Female; Gentamic | 2016 |
Alleviation of renal mitochondrial dysfunction and apoptosis underlies the protective effect of sitagliptin in gentamicin-induced nephrotoxicity.
Topics: Adenosine Triphosphate; Animals; Antioxidants; Apoptosis; Apoptosis Regulatory Proteins; Biomarkers; | 2016 |
Evaluation of novel biomarkers of nephrotoxicity in Cynomolgus monkeys treated with gentamicin.
Topics: Acetylglucosaminidase; Alanine Transaminase; Alpha-Globulins; Animals; Anti-Bacterial Agents; Aspart | 2016 |
Ellagic acid confers protection against gentamicin-induced oxidative damage, mitochondrial dysfunction and apoptosis-related nephrotoxicity.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Apoptosis; Caspase 3; Creatinine; Cytochromes c; Ellag | 2016 |
Organic Cation Transporter 2 Overexpression May Confer an Increased Risk of Gentamicin-Induced Nephrotoxicity.
Topics: Animals; Cell Line; Diet, High-Fat; Female; Gentamicins; HEK293 Cells; Humans; Kidney; Kidney Diseas | 2016 |
Protective Effects of Hydroalcoholic Extract of Ferulago Angulata Against Gentamicin-induced Nephrotoxicity in Rats.
Topics: Animals; Apiaceae; Catalase; Creatinine; Gentamicins; Glutathione; Kidney; Kidney Diseases; Male; Ma | 2016 |
Establishment of Simple and Routine Methods in Early Diagnosis of Gentamicin-Induced Kidney Injury Based on a Rat Model.
Topics: Animals; Biomarkers; Body Weight; Diagnostic Tests, Routine; Disease Models, Animal; Drinking Water; | 2016 |
Renoprotective effect of erythropoietin in zebrafish after administration of gentamicin: an immunohistochemical study for β-catenin and c-kit expression.
Topics: Animals; beta Catenin; Cell Proliferation; Cytoprotection; Disease Models, Animal; Epoetin Alfa; Gen | 2017 |
Antioxidant and anti-inflammatory effects of Nasturtium officinale involved in attenuation of gentamicin-induced nephrotoxicity.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Dose-Response Relationship, Drug; Gentamicins; Kidn | 2017 |
Pimpinella anisum L. ethanolic extract ameliorates the gentamicin- induced nephrotoxicity in rats.
Topics: Animals; Antioxidants; Biomarkers; Disease Models, Animal; Ethanol; Gentamicins; Kidney; Kidney Dise | 2017 |
Riceberry bran extract prevents renal dysfunction and impaired renal organic anion transporter 3 (Oat3) function by modulating the PKC/Nrf2 pathway in gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Antioxidants; Gentamicins; Glutathione; Kidney; Kidney Diseases; Kidney Function Tests; Mal | 2016 |
Nephro-protective effect of a novel formulation of unopened coconut inflorescence sap powder on gentamicin induced renal damage by modulating oxidative stress and inflammatory markers.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Biomarkers; Cocos; Flowers; Gentamicins; Inflammation; | 2017 |
Protective effects of hydroxytyrosol on gentamicin induced nephrotoxicity in mice.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Creatinine; Gentamicins; Kidney; Kidney Diseases; Lipid | 2017 |
Nephroprotective and Anti-Inflammatory Effects of Pistacia atlantica Leaf Hydroethanolic Extract Against Gentamicin-Induced Nephrotoxicity in Rats.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Gentamicins; Kidney; Kidney Diseases; Kidn | 2017 |
Studies on the protective effect of dietary fish oil on gentamicin-induced nephrotoxicity and oxidative damage in rat kidney.
Topics: Animals; Antioxidants; Biological Transport, Active; Blood Glucose; Blood Urea Nitrogen; Carbohydrat | 2008 |
Spirulina platensis protects against gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Antioxidants; Creatine; Gentamicins; Glutathione; Glutathione Peroxidase; Kidney; Kidney Di | 2008 |
Aqueous-ethanolic extract of morel mushroom mycelium Morchella esculenta, protects cisplatin and gentamicin induced nephrotoxicity in mice.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Antioxidants; Ascomycota; Blood Urea Nitrogen | 2008 |
Modification of Diet in Renal Disease and modified Cockcroft-Gault formulas in predicting aminoglycoside elimination.
Topics: Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Body Surface Area; Data Interpretat | 2008 |
Protective effect of quercetin against gentamicin-induced nephrotoxicity in rats.
Topics: Analysis of Variance; Animals; Antioxidants; Blood Urea Nitrogen; Catalase; Creatinine; Drug Interac | 2009 |
Urinary lipocalin-type prostaglandin D synthase: a potential marker for early gentamicin-induced renal damage?
Topics: Acetylglucosaminidase; Algorithms; Anti-Bacterial Agents; beta 2-Microglobulin; Biomarkers; Creatini | 2009 |
Enzymuria determination in children treated with aminoglycosides drugs.
Topics: Acetylglucosaminidase; Albuminuria; Alkaline Phosphatase; Amikacin; Anti-Bacterial Agents; Biomarker | 2008 |
Protective effects of nigella sativa against gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Anti-Bacterial Agents; Free Radical Scavengers; Gentamicins; Kidney; Kidney Diseases; Male; | 2010 |
Peroxisome proliferator-activated receptor alpha plays a crucial role in L-carnitine anti-apoptosis effect in renal tubular cells.
Topics: Animals; Apoptosis; Carnitine; Cells, Cultured; Epoprostenol; Gentamicins; Kidney Diseases; Kidney T | 2009 |
Gender differences in aminoglycoside induced nephrotoxicity: a prospective, hospital-based study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Biomarkers; Creatinine; | 2009 |
Differences in immunolocalization of Kim-1, RPA-1, and RPA-2 in kidneys of gentamicin-, cisplatin-, and valproic acid-treated rats: potential role of iNOS and nitrotyrosine.
Topics: Animals; Antigens; Cell Adhesion Molecules; Cisplatin; Gentamicins; Immunohistochemistry; Kidney; Ki | 2009 |
Protective effect of oleanolic acid on gentamicin induced nephrotoxicity in rats.
Topics: Administration, Oral; Albumins; Animals; Creatinine; Gentamicins; Glomerular Filtration Rate; Kidney | 2010 |
Index of suspicion.
Topics: Abscess; Adolescent; Anti-Bacterial Agents; Brucellosis; Cefuroxime; Child; Doxycycline; Female; Gen | 2009 |
Assessment of novel avian renal disease markers for the detection of experimental nephrotoxicosis in pigeons (Columba livia).
Topics: Acetylglucosaminidase; Animals; Anti-Bacterial Agents; Biomarkers; Bird Diseases; Columbidae; Creati | 2009 |
Pentoxifylline ameliorates glomerular basement membrane ultrastructural changes caused by gentamicin administration in rats.
Topics: Animals; Anti-Bacterial Agents; Apoptosis; Basement Membrane; Gentamicins; Kidney Diseases; Kidney G | 2009 |
Modified diet in renal disease method overestimates renal function in selected elderly patients.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analysis of Variance; Bias; Body Weight; Cr | 2009 |
Rosiglitazone, peroxisome proliferator receptor-gamma agonist, ameliorates gentamicin-induced nephrotoxicity in rats.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Gentamicins; Kidney; Kidney Diseases; Kidney Tubule | 2010 |
Age-related differences in susceptibility to cisplatin-induced renal toxicity.
Topics: Age Factors; Aging; Animals; Biomarkers; Child; Cisplatin; Disease Susceptibility; Gentamicins; Huma | 2010 |
The modifier protein of glyceraldehyde-3-phosphate dehydrogenase reduces free radical-mediated renal damage in a rat model of acute kidney injury.
Topics: Acute Disease; Animals; Chlorocebus aethiops; Creatinine; Disease Models, Animal; Epithelial Cells; | 2010 |
Nephroprotective effect of Withania somnifera: a dose-dependent study.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Disease Models, Animal; Gentamicins; Kidney; Kidney Di | 2009 |
Renoprotective effects of paricalcitol on gentamicin-induced kidney injury in rats.
Topics: Animals; Aquaporin 1; Bone Density Conservation Agents; Carrier Proteins; Cell Adhesion Molecules; C | 2010 |
Attenuation of gentamicin-induced nephrotoxicity: trimetazidine versus N-acetyl cysteine.
Topics: Acetylcysteine; Acetylglucosaminidase; Animals; Biomarkers; Creatinine; Free Radical Scavengers; gam | 2010 |
Green tea ameliorates renal oxidative damage induced by gentamicin in rats.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Camellia sinensis; Creatinine; Drug Evaluation, Preclini | 2010 |
Metformin prevents experimental gentamicin-induced nephropathy by a mitochondria-dependent pathway.
Topics: Acetylglucosaminidase; Animals; Antioxidants; Apoptosis; Cytochrome c Group; Cytochromes c; Electron | 2010 |
Infective endocarditis: long-term reversibility of kidney function impairment. A 1-y post-discharge follow-up study.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Creatinine; Endocarditis; Female; Follow-Up Studies; | 2010 |
The nephroprotective effects of pioglitazone and glibenclamide against gentamicin-induced nephrotoxicity in rats: a comparative study.
Topics: Animals; Antioxidants; Creatinine; Disease Models, Animal; Gentamicins; Glyburide; Kidney Diseases; | 2010 |
Urinary biomarkers trefoil factor 3 and albumin enable early detection of kidney tubular injury.
Topics: Albuminuria; Animals; Biomarkers, Pharmacological; Carbapenems; Cisplatin; Gentamicins; Histocytoche | 2010 |
A panel of urinary biomarkers to monitor reversibility of renal injury and a serum marker with improved potential to assess renal function.
Topics: Animals; Biomarkers, Pharmacological; Blood Urea Nitrogen; Carbapenems; Creatinine; Cystatin C; Drug | 2010 |
Protective effect of Withania somnifera root powder on lipid peroxidation and antioxidant status in gentamicin-induced nephrotoxic rats.
Topics: Animals; Antioxidants; Catalase; Gentamicins; Kidney; Kidney Diseases; Lipid Peroxidation; Liver; Ma | 2010 |
[Effect of Liuwei Dihuang pill on expression of NF-kappaB in kidney lesion induced by gentamicin in rats].
Topics: Animals; Blotting, Western; Disease Models, Animal; Drugs, Chinese Herbal; Gentamicins; Kidney; Kidn | 2010 |
Toxicoepigenetic alteration of the kidney injury molecule 1 gene in gentamicin-exposed rat kidney.
Topics: Acetylation; Animals; Anti-Bacterial Agents; Cell Adhesion Molecules; Chromatin; Gene Expression; Ge | 2010 |
Sida rhomboidea.Roxb leaf extract ameliorates gentamicin induced nephrotoxicity and renal dysfunction in rats.
Topics: Animals; Antioxidants; Dose-Response Relationship, Drug; Female; Gentamicins; Kidney; Kidney Disease | 2010 |
Sesame oil accelerates kidney healing following gentamicin-induced kidney injury in rats.
Topics: Animals; Blood Urea Nitrogen; Cell Proliferation; Creatinine; Gentamicins; Hydroxyl Radical; Kidney; | 2010 |
Evaluation of a urinary kidney biomarker panel in rat models of acute and subchronic nephrotoxicity.
Topics: Acute Disease; Animals; Biomarkers; Chronic Disease; Disease Models, Animal; Gentamicins; Kidney Dis | 2010 |
Effect of nephrotoxic treatment with gentamicin on rats chronically exposed to uranium.
Topics: Animals; Anti-Bacterial Agents; Biomarkers; Cell Adhesion Molecules; Creatinine; Diuresis; Drug Inte | 2011 |
Effect of crocus sativus on gentamicin induced nephrotoxicity.
Topics: Animals; Anti-Bacterial Agents; Crocus; Gentamicins; Kidney Diseases; Male; Malondialdehyde; Plant E | 2010 |
Nitric oxide (NO) is associated with gentamicin (GENTA) nephrotoxicity and the renal function recovery after suspension of GENTA treatment in rats.
Topics: Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Gentamicins; Kidney; Kidney Diseas | 2011 |
Reno-protective role of flunarizine (mitochondrial permeability transition pore inactivator) against gentamicin induced nephrotoxicity in rats.
Topics: Animals; Body Weight; Cyclosporine; Flunarizine; Gentamicins; Kidney Diseases; Male; Mitochondrial M | 2011 |
Protective role of Pleurotus porrigens (Angel's wings) against gentamicin-induced nephrotoxicty in mice.
Topics: Animals; Biomarkers; Blood Urea Nitrogen; Creatinine; Disease Models, Animal; Gentamicins; Injection | 2010 |
Angiotensin II receptor blocker, losartan, ameliorates gentamicin-induced oxidative stress and nephrotoxicity in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Bacterial Agents; Antioxidants; Gentamicins; | 2011 |
Therapeutic effect of ethanolic extract of Hygrophila spinosa T. Anders on gentamicin-induced nephrotoxicity in rats.
Topics: Acanthaceae; Animals; Catalase; Creatinine; Ethanol; Gentamicins; Glutathione; Kidney; Kidney Diseas | 2010 |
Biological qualification of biomarkers of chemical-induced renal toxicity in two strains of male rat.
Topics: Acetylglucosaminidase; Animals; Biomarkers; Blood Urea Nitrogen; Cisplatin; Clusterin; Creatinine; G | 2011 |
Renoprotective effect of grape seed extract against oxidative stress induced by gentamicin and hypercholesterolemia in rats.
Topics: Animals; Atherosclerosis; Gentamicins; Grape Seed Extract; Hypercholesterolemia; Kidney Diseases; Ma | 2011 |
Caffeic acid phenethyl ester modulates gentamicin-induced oxidative nephrotoxicity in kidney of rats.
Topics: Animals; Anti-Bacterial Agents; Caffeic Acids; Creatinine; Female; Gentamicins; Kidney; Kidney Disea | 2012 |
Protective effect of hydrogen-rich water against gentamicin-induced nephrotoxicity in rats using blood oxygenation level-dependent MR imaging.
Topics: Analysis of Variance; Animals; Blood Urea Nitrogen; Creatinine; Gentamicins; Hydrogen; Kidney Diseas | 2011 |
Protective effects of Allium paradoxum against gentamicin-induced nephrotoxicity in mice.
Topics: Allium; Animals; Disease Models, Animal; Gentamicins; Humans; Kidney Diseases; Male; Mice; Plant Ext | 2012 |
Prevention of hepatorenal toxicity with Sonchus asper in gentamicin treated rats.
Topics: Animals; Anti-Bacterial Agents; Gentamicins; Humans; Kidney; Kidney Diseases; Liver; Liver Diseases; | 2011 |
Evaluation of protective and curative role of α-lipoic acid and selenium in gentamicin-induced nephrotoxicity in rabbits.
Topics: Animals; Antioxidants; Blood Urea Nitrogen; Creatinine; Drug Evaluation, Preclinical; Drug Therapy, | 2012 |
Protective effect of Moringa oleifera leaves against gentamicin-induced nephrotoxicity in rabbits.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Gentamicins; Kidney; Kidney Diseases; Kidney Function | 2013 |
Inhibitory effect of olive leaf extract on gentamicin-induced nephrotoxicity in rats.
Topics: Analysis of Variance; Animals; Antioxidants; Catalase; Creatinine; Gentamicins; Glutathione; Glutath | 2012 |
Increased urinary podocytes following indomethacin suggests drug-induced glomerular injury.
Topics: Anti-Bacterial Agents; Cardiovascular Agents; Drug Therapy, Combination; Ductus Arteriosus, Patent; | 2012 |
Melatonin attenuates gentamicin-induced nephrotoxicity and oxidative stress in rats.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Apoptosis; Blood Urea Nitrogen; Creatinine; Gentamicin | 2012 |
Inhibition of cystathionine gamma-lyase and the biosynthesis of endogenous hydrogen sulphide ameliorates gentamicin-induced nephrotoxicity.
Topics: Alkynes; Animals; Anti-Bacterial Agents; Cystathionine gamma-Lyase; Female; Gentamicins; Glycine; Hy | 2012 |
Gentamicin ototoxicity: a 23-year selected case series of 103 patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Australia; Delayed Diagnosis; Dos | 2012 |
[Therapeutic effect of acetylcysteine on rats with gentamicin-induced nephropathy].
Topics: Acetylcysteine; Alkaline Phosphatase; Animals; Anti-Bacterial Agents; Creatinine; Female; Gentamicin | 2012 |
Nephro-protective effect of vitamin C and Nigella sativa oil on gentamicin associated nephrotoxicity in rabbits.
Topics: Animals; Antioxidants; Ascorbic Acid; Biomarkers; Blood Urea Nitrogen; Creatinine; Cytoprotection; D | 2012 |
Renoprotective effects of the crude extract and solvent fractions of the leaves of Euclea divinorum Hierns against gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Antioxidants; Catalase; Ebenaceae; Female; Gentamicins; Glutathione; Kidney Diseases; Lipid | 2013 |
The effect of calcium load and the calcium channel blocker verapamil on gentamicin nephrotoxicity in rats.
Topics: Animals; Anti-Bacterial Agents; Calcium; Calcium Channel Blockers; Creatinine; Dose-Response Relatio | 2002 |
L-carnitine ameliorates gentamicin-induced renal injury in rats.
Topics: Animals; Carnitine; Dose-Response Relationship, Drug; Drug Administration Schedule; Gentamicins; Inj | 2002 |
Effects of gentamicin, lipopolysaccharide, and contrast media on immortalized proximal tubular cells.
Topics: Animals; Anti-Bacterial Agents; Apoptosis; Calcium; Contrast Media; Disease Models, Animal; Gentamic | 2002 |
Aminoglycoside-induced reversible tubular dysfunction.
Topics: Aged; Alkalosis; Anti-Bacterial Agents; Drug Administration Schedule; Female; Gentamicins; Humans; H | 2003 |
Protective effect of trans-resveratrol on gentamicin-induced nephrotoxicity.
Topics: Acetylglucosaminidase; Alkaline Phosphatase; Animals; Anti-Bacterial Agents; Antioxidants; Electroly | 2002 |
Once-daily dosing of aminoglycosides: how much monitoring is truly required?
Topics: Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Monitori | 2003 |
Quantitative renal scintigraphy in domestic pigeons (Columba livia domestica) exposed to toxic doses of gentamicin.
Topics: Animals; Anti-Bacterial Agents; Bird Diseases; Gentamicins; Kidney; Kidney Diseases; Radionuclide Im | 2003 |
Increasing antibiotic resistance among urinary tract isolates.
Topics: Adolescent; Anti-Bacterial Agents; Cefuroxime; Child; Ciprofloxacin; Drug Resistance, Bacterial; Esc | 2003 |
Assessing residents' prescribing behavior in renal impairment.
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Anti-Bacterial Agents | 2003 |
Diallyl disulfide ameliorates gentamicin-induced oxidative stress and nephropathy in rats.
Topics: Allyl Compounds; Animals; Anti-Bacterial Agents; Antioxidants; Biomarkers; Blood Urea Nitrogen; Disu | 2003 |
Aged garlic extract attenuates gentamicin induced renal damage and oxidative stress in rats.
Topics: Animals; Anti-Bacterial Agents; Blotting, Western; Body Weight; Catalase; Free Radical Scavengers; G | 2003 |
The effect of manganese chloride on gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Catalase; Chlorides; Creatinine; Gentamicins; Glutathione; Glutathione Peroxidase; Kidney; | 2003 |
S-allylmercaptocysteine scavenges hydroxyl radical and singlet oxygen in vitro and attenuates gentamicin-induced oxidative and nitrosative stress and renal damage in vivo.
Topics: Aldehydes; Animals; Biomarkers; Body Weight; Carboxylic Acids; Cysteine; Dinitrophenols; Energy Inta | 2004 |
Diuretic and nephroprotective effect of Jawarish Zarooni Sada--a polyherbal unani formulation.
Topics: Animals; Creatinine; Diuretics; Female; Gentamicins; India; Kidney; Kidney Diseases; Kidney Function | 2004 |
The effect of Nigella sativa oil on gentamicin nephrotoxicity in rats.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Gentamicins; | 2004 |
Renoprotective effect of Hemidesmus indicus, a herbal drug used in gentamicin-induced renal toxicity.
Topics: Animals; Gentamicins; Hemidesmus; Kidney Diseases; Mice; Phytotherapy; Plant Preparations; Quality C | 2004 |
Altered NMDA receptor expression in renal toxicity: Protection with a receptor antagonist.
Topics: Animals; Anti-Bacterial Agents; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amin | 2004 |
Influence of spironolactone treatment on gentamicin-induced nephrotoxicity in rats.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Body Weight; Creatinine; Drug Synergism; Genta | 2004 |
Urinary guanidinoacetic acid excretion as an indicator of gentamicin nephrotoxicity in rats.
Topics: Animals; Anti-Bacterial Agents; Biomarkers; Early Diagnosis; Gentamicins; Glycine; Kidney Diseases; | 2004 |
Effect of Rheum emodi (Revand Hindi) on renal functions in rats.
Topics: Animals; Antioxidants; Cadmium Chloride; Female; Gentamicins; Kidney Diseases; Kidney Tubules, Proxi | 2005 |
Effects of co-supplementation of vitamins E and C on gentamicin-induced nephrotoxicity in rat.
Topics: Acetylglucosamine; Acetylglucosaminidase; Alkaline Phosphatase; Animals; Anti-Bacterial Agents; Anti | 2005 |
Improved compliance with a gentamicin prescribing policy after introduction of a monitoring form.
Topics: Anti-Bacterial Agents; Drug Monitoring; Drug Prescriptions; Drug Utilization; Drug Utilization Revie | 2005 |
Short-term exposure of renal proximal tubules to gentamicin increases long-term multidrug resistance protein 2 (Abcc2) transport function and reduces nephrotoxicant sensitivity.
Topics: Animals; Cyclic GMP; Drug Resistance; Enzyme Inhibitors; Fundulidae; Gentamicins; Immunohistochemist | 2005 |
Parachlorophenylalanine exacerbates oxidative stress induced by gentamicin in rats.
Topics: Animals; Blood Urea Nitrogen; Brain; Brain Chemistry; Catalase; Creatinine; Drug Synergism; Fencloni | 2005 |
Development of a technique for serial bilateral renal biopsy in steers.
Topics: Anesthesia, Local; Animals; Biopsy, Needle; Cattle; Cattle Diseases; Drug Residues; Gentamicins; Inj | 2006 |
Biomarker discovery by imaging mass spectrometry: transthyretin is a biomarker for gentamicin-induced nephrotoxicity in rat.
Topics: Amino Acid Sequence; Animals; Biomarkers; Blotting, Western; Gentamicins; Kidney; Kidney Diseases; M | 2006 |
Curcumin attenuates gentamicin-induced renal oxidative damage in rats.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Antioxidants; Curcumin; Disease Models, Animal | 2006 |
Selective nuclear factor kappa-B inhibitors, pyrolidium dithiocarbamate and sulfasalazine, prevent the nephrotoxicity induced by gentamicin.
Topics: Animals; Gentamicins; I-kappa B Proteins; Immunohistochemistry; Kidney Diseases; Male; NF-kappa B; N | 2006 |
Grape seed extract prevents gentamicin-induced nephrotoxicity and genotoxicity in bone marrow cells of mice.
Topics: Animals; Antioxidants; Bone Marrow Cells; Creatinine; Drug Antagonism; Gentamicins; Glutathione; Glu | 2006 |
Protective effect of ebselen, a selenoorganic drug, against gentamicin-induced renal damage in rats.
Topics: Animals; Azoles; Creatinine; Gentamicins; Glutathione; Glutathione Peroxidase; Isoindoles; Kidney; K | 2006 |
Comparative effects of selective and non-selective nitric oxide synthase inhibition in gentamicin-induced rat nephrotoxicity.
Topics: Acetylglucosaminidase; Animals; Creatinine; Disease Models, Animal; Enzyme Inhibitors; Gentamicins; | 2007 |
Gentamicin-induced nephrotoxicity in rats ameliorated and healing effects of resveratrol.
Topics: Animals; Anti-Bacterial Agents; Antioxidants; Catalase; Creatinine; Gentamicins; Glutathione; Glutat | 2007 |
Effect of carnosine on gentamicin-induced nephrotoxicity.
Topics: Animals; Carnosine; Enzymes; Gentamicins; Kidney Diseases; Kidney Function Tests; Kidney Glomerulus; | 2007 |
Dietary protein level alters gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Anti-Bacterial Agents; Caseins; Circadian Rhythm; Corticosterone; Dietary Proteins; Eating; | 2007 |
"Subclinical" gentamicin nephrotoxicity: a potential risk factor for exaggerated endotoxin-driven TNF-alpha production.
Topics: Animals; Anti-Bacterial Agents; Chemokine CCL2; Endotoxins; Gentamicins; Glyceraldehyde-3-Phosphate | 2007 |
Cisplatin, gentamicin, and p-aminophenol induce markers of endoplasmic reticulum stress in the rat kidneys.
Topics: Aminophenols; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Apoptosis; Basic-Leucine Zipper | 2007 |
A 'Yang-Invigorating' Chinese herbal formula protects against gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Antioxidants; Drugs, Chinese Herbal; Gentamicins; Glutathione; Glutathione Transferase; Kid | 2008 |
Comparison of kidney injury molecule-1 and other nephrotoxicity biomarkers in urine and kidney following acute exposure to gentamicin, mercury, and chromium.
Topics: Acetylglucosamine; Animals; Biomarkers; Cell Adhesion Molecules; Chemical and Drug Induced Liver Inj | 2008 |
Would you appeal a $3.2 million verdict in your favor? Case on point: Kunz v. Little Co. of Mary Hosp., 869 N.E. 328 -IL (2007).
Topics: Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Continuity of Patient Care; Cross Infe | 2007 |
Long-term treatment with a Yang-invigorating Chinese herbal formula produces generalized tissue protection against oxidative damage in rats.
Topics: Animals; Carbon Tetrachloride; Carnosine; Chemical and Drug Induced Liver Injury; Cholecalciferol; C | 2008 |
Time dependent effects of gentamicin on the enzymes of carbohydrate metabolism, brush border membrane and oxidative stress in rat kidney tissues.
Topics: Alkaline Phosphatase; Animals; Anti-Bacterial Agents; Carbohydrate Metabolism; Catalase; gamma-Gluta | 2008 |
Validation of putative genomic biomarkers of nephrotoxicity in rats.
Topics: Animals; Anti-Bacterial Agents; Antineoplastic Agents; Bacitracin; Cisplatin; Gene Expression; Gene | 2008 |
Schisandrin B Enhances Renal Mitochondrial Antioxidant Status, Functional and Structural Integrity, and Protects against Gentamicin-Induced Nephrotoxicity in Rats.
Topics: Adenosine Triphosphate; Animals; Antibiotics, Antineoplastic; Antioxidants; Ascorbic Acid; Cycloocta | 2008 |
Glomerular basement membrane alterations induced by gentamicin administration in rats.
Topics: Animals; Anti-Bacterial Agents; Creatinine; Gentamicins; Glomerular Basement Membrane; Injections, I | 2008 |
Gentamicin-induced nephrotoxicity: a cell biology approach.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Animals; Cell Fractionation; gamma-Glutamyltransferase; | 1980 |
Gentamicin and sisomicin - induced renal tubular damage.
Topics: Acetylglucosaminidase; Aminopeptidases; CD13 Antigens; Female; Gentamicins; Humans; Kidney Diseases; | 1982 |
Predictive value of urinary N-acetyl-beta-D-glucosaminidase (NAG), alanine-aminopeptidase (AAP) and beta-2-microglobulin (beta 2M) in evaluating nephrotoxicity of gentamicin.
Topics: Acetylglucosaminidase; Aged; Aminopeptidases; beta 2-Microglobulin; Beta-Globulins; CD13 Antigens; E | 1981 |
[Drug induced nephropathy and enzymes of renal origin in the urine].
Topics: Acetylglucosaminidase; Adolescent; Adult; alpha-Galactosidase; Aminopeptidases; Anti-Bacterial Agent | 1982 |
Interactions between mezlocillin and sisomicin in vitro and in patients with normal and various degrees of impaired renal function.
Topics: Adolescent; Adult; Aged; Drug Interactions; Female; Gentamicins; Humans; In Vitro Techniques; Kidney | 1983 |
[Clinico-biochemical study of experimental renal injuries in rats. 3. Relations between serum half-life of phenolsulfonphthalein and renal injuries].
Topics: Animals; Bile; Blood Proteins; Female; Gentamicins; Half-Life; Kidney; Kidney Diseases; Kidney Funct | 1983 |
Renal cortex ion composition and Na-K-ATPase activity in gentamicin nephrotoxicity.
Topics: Animals; Creatinine; Dogs; Electrolytes; Gentamicins; Ions; Kidney Cortex; Kidney Diseases; Male; Mi | 1982 |
Protocol for the study of drug interferences in laboratory tests: cefotaxime interference in 24 clinical tests.
Topics: Blood Chemical Analysis; Cefotaxime; False Positive Reactions; Female; Gentamicins; Heart Diseases; | 1983 |
Absorption of oral aminoglycosides following bone marrow transplantation.
Topics: Adolescent; Adult; Aminoglycosides; Bone Marrow Transplantation; Child; Combined Modality Therapy; F | 1984 |
Aminoglycoside-related nephrotoxicity in the premature newborn.
Topics: Acetylglucosaminidase; Amikacin; beta 2-Microglobulin; Chloramphenicol; Creatinine; Gentamicins; Hum | 1984 |
Renal and auditory toxicity of high-dose, prolonged therapy with gentamicin and tobramycin in pseudomonas endocarditis.
Topics: Adult; Auditory Threshold; Creatinine; Endocarditis, Bacterial; Female; Gentamicins; Hearing Loss; H | 1984 |
Gentamicin nephrotoxicity in cadmium, lead and mercury pretreated rats.
Topics: Amino Acids; Animals; beta-Galactosidase; Cadmium Poisoning; Drug Interactions; Female; Gentamicins; | 1983 |
[Nephrotoxicity of gentamicin and mercury in experiments on rats (author's transl)].
Topics: Acetylglucosaminidase; Animals; Clinical Enzyme Tests; Gentamicins; Kidney Diseases; Male; Mercuric | 1981 |
Nephrotoxic and ototoxic effects of hydroxygentamicin in cats.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Blood Urea Nitrogen; Cats; Creatinine; Female; Gent | 1984 |
Comparative nephrotoxicity of hydroxygentamicin and other aminoglycosides in rats.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Blood Urea Nitrogen; Body Weight; Creatin | 1984 |
Aminoglycoside-induced functional and biochemical defects in the renal cortex.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Biological Transport, Active; Cell Membrane; Gentam | 1984 |
Effect of physiological manipulations on the chemotherapy of experimentally induced renal infection.
Topics: Ampicillin; Animals; Anti-Infective Agents, Urinary; Carbenicillin; Diuresis; Drug Combinations; Fem | 1983 |
Patient selection for serum gentamicin levels.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Female; Gentamicins; Humans; Kidney Diseases; Male; M | 1983 |
Specificity of renal tubular damage criteria for aminoglycoside nephrotoxicity in critically ill patients.
Topics: Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Critical Care; Female; Gentamicins; Glomerular | 1983 |
Renal and hepatic function in rats treated with cyclosporin A in combination with gentamicin or cephalosporin antibiotics.
Topics: Acetylglucosaminidase; Acute Kidney Injury; Animals; Blood Proteins; Cephalosporins; Chemical and Dr | 1983 |
Clinical experience with a method for adjusting gentamicin dose from measured drug clearance.
Topics: Adult; Aged; Bacterial Infections; Creatinine; Female; Gentamicins; Humans; Kidney Diseases; Male; M | 1983 |
Morphological and functional aspects of experimental gentamicin nephrotoxicity in young beagles and foals.
Topics: Animals; Dogs; Gentamicins; Horses; Kidney; Kidney Diseases | 1983 |
Comparison of methods for estimating gentamicin clearance and retrospective analysis of changes in clearance with emphasis on patients with normal renal function.
Topics: Adult; Aged; Female; Gentamicins; Half-Life; Humans; Kidney Diseases; Kinetics; Male; Methods; Middl | 1984 |
Gentamicin, netilmicin, dibekacin, and amikacin nephrotoxicity and its relationship to tubular reabsorption in rabbits.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Blood Proteins; Dibekacin; Gentamicins; K | 1984 |
The association of aminoglycoside plasma levels with mortality in patients with gram-negative bacteremia.
Topics: Adult; Aged; Amikacin; Body Temperature; Gentamicins; Gram-Negative Bacteria; Humans; Kanamycin; Kid | 1984 |
Nephrotoxic effects of aminoglycoside treatment on renal protein reabsorption and accumulation.
Topics: Absorption; Aminoglycosides; Animals; Anti-Bacterial Agents; Gentamicins; Kanamycin; Kidney; Kidney | 1984 |
Drugs and the neonatal kidney.
Topics: Asphyxia Neonatorum; Captopril; Gentamicins; Humans; Hypoxia; Indomethacin; Infant, Newborn; Infant, | 1982 |
Indomethacin and gentamycin treatment in experimental kidney infection.
Topics: Animals; Antibodies, Bacterial; Drug Therapy, Combination; Escherichia coli Infections; Female; Gent | 1982 |
Renal function during cefuroxime treatment in patients with pre-existing renal impairment.
Topics: Cefuroxime; Cephaloridine; Cephalosporins; Edetic Acid; Furosemide; Gentamicins; Glomerular Filtrati | 1980 |
Failure of lysine to prevent experimental gentamicin nephrotoxicity.
Topics: Animals; Dogs; Gentamicins; Kidney Diseases; Lysine; Male; Rabbits; Rats | 1982 |
[Study on the dose-regimen of gentamicin].
Topics: Drug Administration Schedule; Gentamicins; Humans; Infusions, Parenteral; Injections, Intramuscular; | 1982 |
The enhancement of cyclosporin A-induced nephrotoxicity by gentamicin.
Topics: Acetylglucosaminidase; Animals; Creatinine; Cyclosporins; Dose-Response Relationship, Drug; Drug Syn | 1983 |
Influence of age on amikacin pharmacokinetics in patients without renal disease. Comparison with gentamicin and tobramycin.
Topics: Adult; Age Factors; Aged; Amikacin; Anti-Bacterial Agents; Creatinine; Female; Gentamicins; Humans; | 1983 |
[Nephrotoxicity of gentamicin in mice].
Topics: Animals; Female; Gentamicins; Injections, Intraperitoneal; Injections, Subcutaneous; Kidney Diseases | 1982 |
Netilmicin therapy of serious renal and urinary tract infections in patients with normal and impaired renal function.
Topics: Adult; Aged; Creatinine; Female; Gentamicins; Humans; Kidney Diseases; Male; Middle Aged; Netilmicin | 1980 |
[Hypomagnesemic coma during therapy of septicaemia in a patient with acute lymphoblastic leukemia. (author's transl)].
Topics: Child; Coma; Furosemide; Gentamicins; Humans; Kidney Diseases; Leukemia, Lymphoid; Magnesium; Magnes | 1981 |
Early toxic events in kidney of rat and man following administration of gentamicin at low doses.
Topics: Animals; Gentamicins; Humans; Kidney Diseases; Kidney Tubules; Rats; Species Specificity; Time Facto | 1982 |
Clinical application of aminoglycosides.
Topics: Aminoglycosides; Anti-Bacterial Agents; Gentamicins; Humans; Kidney Diseases; Labyrinth Diseases; La | 1982 |
Intrarenal abscess. Report of 14 cases.
Topics: Abscess; Adolescent; Adult; Ampicillin; Escherichia coli Infections; Female; Gentamicins; Humans; Ki | 1980 |
Gentamicin treatment in severe surgical infections--serum levels, interactions, toxicity and efficacy.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Candidiasis; Drug Therapy, Combination; En | 1981 |
Successful percutaneous management of renal abscess.
Topics: Abscess; Adult; Aged; Ampicillin; Drainage; Escherichia coli Infections; Female; Gentamicins; Humans | 1982 |
Gentamicin v. Tobramycin.
Topics: Animals; Anti-Bacterial Agents; Gentamicins; Humans; Kidney Diseases; Tobramycin | 1982 |
Effect of basis amino acids and aminoglycosides on 3H-gentamicin uptake in cortical slices of rat and human kidney.
Topics: Amino Acids; Aminoglycosides; Animals; Biological Transport, Active; Gentamicins; Humans; In Vitro T | 1982 |
Aminoglycosides induce a phospholipidosis in the renal cortex of the rat: an early manifestation of nephrotoxicity.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Gentamicins; Kidney Cortex; Kidney Diseases; Lipido | 1982 |
Nephrotoxicity of aminoglycoside antibiotics in laboratory animals and its predictive value: effects of gentamicin in the rat.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Female; Gentamicins; Kidney Diseases; Male; Rats; R | 1982 |
Gentamicin toxic nephropathy in horses with disseminated bacterial infection.
Topics: Animals; Arthritis, Infectious; Bacterial Infections; Enteritis; Female; Gentamicins; Horse Diseases | 1982 |
Renal handling of gentamicin by normal and ischemic canine kidneys.
Topics: Absorption; Animals; Constriction; Disease Models, Animal; Dogs; Gentamicins; Ischemia; Kidney; Kidn | 1982 |
Clinical and pharmacokinetic characteristics of aminoglycoside nephrotoxicity in 201 critically ill patients.
Topics: Aminoglycosides; Anti-Bacterial Agents; Critical Care; Gentamicins; Humans; Kidney Diseases; Kidney | 1982 |
Comparative nephrotoxicity of two aminoglycosides: gentamicin and tobramycin.
Topics: Adult; Anti-Bacterial Agents; Creatinine; Drug Evaluation; Female; Gentamicins; Humans; Kidney; Kidn | 1982 |
Evaluation of gentamicin prescribing after drug-use review.
Topics: Creatinine; Drug Prescriptions; Drug Utilization; Gentamicins; Humans; Kidney Diseases | 1982 |
Renal function of neonates during gentamicin treatment.
Topics: Bacterial Infections; Female; Gentamicins; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infan | 1982 |
The toxic effects of combined administration of cyclosporin A and gentamicin.
Topics: Acetylglucosaminidase; Animals; Aspartate Aminotransferases; Blood Proteins; Bone Marrow; Chemical a | 1982 |
Renal damage in gentamicin-treated lanner falcons.
Topics: Animals; Bird Diseases; Birds; Feces; Gentamicins; Kidney Diseases | 1982 |
Renal effects of an aminoglycoside antibiotic in the rat.
Topics: Acid Phosphatase; Alkaline Phosphatase; Animals; Gentamicins; Glutamate Dehydrogenase; Kidney Diseas | 1982 |
Influence of age and lean body mass on the relation of creatinine clearance and drug half-life.
Topics: Adolescent; Aging; Amikacin; Body Weight; Child; Child, Preschool; Creatinine; Female; Gentamicins; | 1982 |
[Magnesium-losing nephropathy due to gentamicin].
Topics: Female; Gentamicins; Humans; Kidney Diseases; Magnesium; Middle Aged; Water-Electrolyte Imbalance | 1982 |
Hearing loss in end-stage renal disease - effect of dialysis.
Topics: Furosemide; Gentamicins; Hearing Disorders; Humans; Kanamycin; Kidney Diseases; Male; Renal Dialysis | 1980 |
Analog computer monitoring and evaluation of a dosing nomogram for gentamicin based on the C'min-method, part II.
Topics: Adolescent; Adult; Aged; Computers; Female; Gentamicins; Humans; Kidney Diseases; Male; Middle Aged; | 1980 |
Gentamicin-induced nephrotoxicity in mice: protection by loop diuretics.
Topics: Acetylglucosaminidase; Bumetanide; Diuretics; Furosemide; Gentamicins; Kidney; Kidney Diseases; Kidn | 1981 |
Gentamicin and ticarcillin in subjects with end-stage renal disease. Comparison of two assay methods and evaluation of inactivation rate.
Topics: Adult; Biological Assay; Drug Interactions; Female; Gentamicins; Humans; Kidney Diseases; Male; Midd | 1981 |
Selected aspects of aminoglycoside antibiotic nephrotoxicosis.
Topics: Aminoglycosides; Animals; Animals, Domestic; Anti-Bacterial Agents; Dog Diseases; Dogs; Gentamicins; | 1981 |
Urinary ligandin and glutathione-S-transferase in gentamicin-induced nephrotoxicity in the rat.
Topics: Animals; Creatinine; Disease Models, Animal; Female; Gentamicins; Glutathione Transferase; Kidney Di | 1981 |
Frusemide enhancement of netilmicin nephrotoxicity in dogs.
Topics: Animals; Blood Urea Nitrogen; Creatinine; Dogs; Furosemide; Gentamicins; Glucuronidase; Hexosaminida | 1981 |
Use of urinary enzyme activities in the early detection of aminoglycoside nephrotoxicity: a study in children and adults receiving gentamicin or netilmicin.
Topics: Adult; Child; Creatinine; Double-Blind Method; Enzymes; Female; Gentamicins; Humans; Kidney Diseases | 1981 |
[Urinary N-acetyl-beta-glucosaminidase as index of renal toxicity (author's transl)].
Topics: Acetylglucosaminidase; Animals; Aspirin; Gentamicins; Hexosaminidases; Kidney Diseases; Male; Mice | 1981 |
Update on drug therapy: IX. Gentamicin and tobramycin nephrotoxicity.
Topics: Anti-Bacterial Agents; Double-Blind Method; Gentamicins; Humans; Kidney Diseases; Prospective Studie | 1981 |
Gentamicin nephrotoxicity in the dog: sequential light and electron microscopy.
Topics: Animals; Blood Urea Nitrogen; Dogs; Gentamicins; Histocytochemistry; Kidney; Kidney Diseases; Male | 1980 |
The safety of cefuroxime and gentamicin in patients with reduced renal function.
Topics: Acute Kidney Injury; Adult; Aged; Bacteriuria; Cefuroxime; Cephalosporins; Drug Therapy, Combination | 1980 |
Effect of timing of cefuroxime dosage on its protection of rats against gentamicin nephrotoxicity.
Topics: Animals; Cefuroxime; Cephalosporins; Gentamicins; Kidney; Kidney Diseases; Male; Rats; Time Factors | 1980 |
Lysozymuria and gentamicin nephrotoxicity.
Topics: Adult; Aged; Gentamicins; Humans; Kidney Diseases; Middle Aged; Muramidase | 1980 |
A rational approach to nephrotoxic drugs in the elderly.
Topics: Aged; Analgesics; Contrast Media; Drug-Related Side Effects and Adverse Reactions; Gentamicins; Gold | 1980 |
Urinary enzyme assays as a quantitative evaluation of drug induced nephrotoxicity.
Topics: Acid Phosphatase; Animals; Blood Urea Nitrogen; Creatinine; Dogs; Enzymes; Gentamicins; Kidney Disea | 1980 |
Toxicity of gentamicin and tobramycin.
Topics: Anti-Bacterial Agents; Gentamicins; Hearing Disorders; Humans; Kidney Diseases; Tobramycin | 1980 |
Gentamicin vs. tobramycin.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Costs and Cost Analysis; Dogs; Gentamicins; Humans; Kidney | 1980 |
Pathophysiologic evidence of gentamicin nephrotoxicity in neonatal puppies.
Topics: Animals; Animals, Newborn; Dogs; Gentamicins; Kidney Cortex; Kidney Diseases | 1980 |
Renal function in Fischer 344 rats with chronic renal impairment after administration of enflurane and gentamicin.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Body Weight; Chronic Disease; Creatinine; Enflura | 1980 |
Effect of osmotic diuresis on gentamicin-induced nephrotoxicity in rats.
Topics: Acetylglucosaminidase; Animals; Diuresis; Diuretics, Osmotic; Dose-Response Relationship, Drug; Gent | 1980 |
Aminoglycoside nephrotoxicity.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Biological Transport; Cephalosporins; Diffusion; Dr | 1980 |
Effects of gentamicin on iron and copper contents of kidney tissue.
Topics: Animals; Copper; Gentamicins; Guinea Pigs; Iron; Kidney; Kidney Diseases | 1995 |
Study on the role of urine gamma-glutamyl transpeptidase activity during investigation of nephrotoxicity.
Topics: Animals; Anti-Bacterial Agents; Blood Glucose; gamma-Glutamyltransferase; Gentamicins; Glycosuria; K | 1994 |
Influence of intraperitoneal gentamicin on peritoneal transport in IPD patients.
Topics: Adult; Aged; Anti-Bacterial Agents; Chronic Disease; Creatinine; Dialysis Solutions; Female; Gentami | 1995 |
Molecular basis of the inhibition of gentamicin nephrotoxicity by daptomycin; an infrared spectroscopic investigation.
Topics: Amino Acid Sequence; Daptomycin; Drug Interactions; Gentamicins; Humans; Kidney Diseases; Liposomes; | 1995 |
Pharmacokinetics, nephrotoxicosis, and in vitro antibacterial activity associated with single versus multiple (three times) daily gentamicin treatments in horses.
Topics: Animals; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gentamicins; Horses | 1995 |
Co-oxydextran as a protectant against gentamicin-induced renal lysosomal phospholipidosis and focal tubular necrosis. Perspectives and limitations.
Topics: Animals; Anions; Cell Division; Dextrans; Female; Gentamicins; Kidney Diseases; Kidney Tubular Necro | 1993 |
Effect of fish oil treatment on gentamicin nephrotoxicity in rats.
Topics: Acetylglucosaminidase; Animals; Creatinine; Dose-Response Relationship, Drug; Fish Oils; Gentamicins | 1994 |
Gentamicin-induced kidney damage and lipid peroxidation in rats.
Topics: Animals; Fatty Acids; Gentamicins; In Vitro Techniques; Kidney; Kidney Diseases; Lipid Peroxidation; | 1995 |
Protection against gentamicin nephrotoxicity by daptomycin in nephrectomized rats.
Topics: Animals; Creatinine; Daptomycin; Female; Gentamicins; Kidney Cortex; Kidney Diseases; Kidney Tubules | 1995 |
The effect of thyroxine or carbimazole treatment on gentamicin nephrotoxicity in rats.
Topics: Animals; Body Weight; Carbimazole; Creatinine; Female; Gentamicins; Kidney Diseases; Rats; Rats, Spr | 1995 |
The effect of verapamil on the nephrotoxic potential of gentamicin as measured by urinary enzyme excretion in healthy volunteers.
Topics: Adolescent; Adult; CD13 Antigens; Delayed-Action Preparations; Drug Administration Schedule; Gentami | 1995 |
Dietary vitamin E supplementation ameliorates renal injury in chronic puromycin aminonucleoside nephropathy.
Topics: Animals; Blood Pressure; Chronic Disease; Diet; Dose-Response Relationship, Drug; Gentamicins; Kidne | 1995 |
Allopurinol fails to protect against gentamicin-induced renal damage in normotensive and spontaneously hypertensive rats.
Topics: Allopurinol; Animals; Gentamicins; Hypertension, Renal; Kidney Diseases; Male; Oxygen; Rats; Rats, I | 1994 |
Methimazole protection of rats against gentamicin-induced nephrotoxicity.
Topics: Animals; Blood Urea Nitrogen; Gentamicins; In Vitro Techniques; Kidney Cortex; Kidney Diseases; Male | 1994 |
Protective effects of cyclodextrin sulphates against gentamicin-induced nephrotoxicity in the rat.
Topics: Animals; Cyclodextrins; Gentamicins; Kidney Diseases; Kidney Tubules, Proximal; Male; Nephrons; Rats | 1993 |
Plasma lipid profile in rats with gentamicin-induced nephrotoxicity.
Topics: Alkaline Phosphatase; Animals; Body Weight; Cholesterol; Creatinine; Female; Gentamicins; Injections | 1993 |
Effects of dietary protein conditioning on gentamicin-induced nephrotoxicosis in healthy male dogs.
Topics: Acetylglucosaminidase; Animals; Creatinine; Dietary Proteins; Dogs; gamma-Glutamyltransferase; Genta | 1994 |
Effects of iotrolan, iopamidol, and iopromide in rats with and without experimental nephropathy.
Topics: Acetylglucosaminidase; Animals; Contrast Media; Doxorubicin; gamma-Glutamyltransferase; Gentamicins; | 1994 |
Oxygen free radicals are not the main factor in experimental gentamicin nephrotoxicity.
Topics: Animals; Free Radicals; Gentamicins; Glutathione; Kidney; Kidney Diseases; Lipid Peroxidation; Male; | 1994 |
Gentamicin vestibulotoxicity.
Topics: Adult; Aged; Aged, 80 and over; Female; Gentamicins; Humans; Infusions, Intravenous; Injections, Int | 1994 |
Attenuation by daptomycin of gentamicin-induced experimental nephrotoxicity.
Topics: Animals; Creatinine; Daptomycin; DNA; Female; Gentamicins; Immunohistochemistry; Kidney; Kidney Cort | 1994 |
[Study on gamma-GTP activity in urine and renal tissue of drug-induced nephrotoxicity in rats].
Topics: Animals; Cephaloridine; Cisplatin; gamma-Glutamyltransferase; Gentamicins; Kidney; Kidney Diseases; | 1993 |
Effect of nephrotoxic drugs on the development of radiation nephropathy after bone marrow transplantation.
Topics: Amphotericin B; Animals; Bone Marrow Transplantation; Busulfan; Cyclosporine; Gentamicins; Kidney; K | 1994 |
Mechanisms for protective effects of free radical scavengers on gentamicin-mediated nephropathy in rats.
Topics: Acetylglucosaminidase; Animals; Cyclic GMP; Endothelins; Free Radical Scavengers; Gentamicins; Kidne | 1994 |
Influence of circadian-stage-dependent dosing schedule on nephrotoxicity and pharmacokinetics of isepamicin in rats.
Topics: Animals; Anti-Bacterial Agents; Circadian Rhythm; Gentamicins; Injections, Subcutaneous; Kidney Dise | 1993 |
Comparative modulating effects of captopril, diltiazem, dietary calcium and pyridoxal-5'-phosphate on gentamicin-induced nephrotoxicity in the rat.
Topics: Animals; Body Weight; Calcium, Dietary; Captopril; Diltiazem; Female; Gentamicins; Glutathione; Inje | 1993 |
Serum angiotensin-converting enzyme activity in rats with gentamicin-induced nephrotoxicity.
Topics: Animals; Captopril; Creatinine; Female; Gentamicins; Kidney Diseases; Peptidyl-Dipeptidase A; Rats; | 1993 |
Lack of in vivo evidence of a cytochrome P450 metabolite participating in aminoglycoside nephrotoxicity.
Topics: Animals; Antipyrine; Cytochrome P-450 Enzyme System; Gentamicins; Kidney Diseases; Liver; Male; Prot | 1993 |
Inhibition of gentamicin-induced nephrotoxicity by lithium in rat.
Topics: Animals; Gentamicins; Kidney; Kidney Diseases; Kidney Tubules; Lipidoses; Lithium; Lysosomes; Male; | 1993 |
Pharmacologic limits of the protective effect of polyaspartic acid on experimental gentamicin nephrotoxicity.
Topics: Animals; Creatinine; Gentamicins; Injections, Subcutaneous; Kidney; Kidney Cortex; Kidney Diseases; | 1993 |
Effect of Sairei-to on gentamicin nephrotoxicity in rats.
Topics: Acetylglucosaminidase; Animals; Creatinine; Drugs, Chinese Herbal; Gentamicins; Kidney Cortex; Kidne | 1993 |
Guanidinoacetic acid (GAA) synthesis in rat tubular suspension as a system for evaluating gentamicin (GM) nephrotoxicity.
Topics: Animals; Anti-Bacterial Agents; Diuretics; Dose-Response Relationship, Drug; Furosemide; Gentamicins | 1995 |
Effect of NG-nitro-L-arginine methyl ester on nephrotoxicity induced by gentamicin in rats.
Topics: Animals; Arginine; Blood Pressure; Creatinine; Enzyme Inhibitors; Gentamicins; Kidney; Kidney Diseas | 1995 |
[Studies on the mechanisms of renal damages induced by nephrotoxic compounds].
Topics: Animals; Antioxidants; Cephaloridine; Cisplatin; Gentamicins; Glycerol; Humans; Kidney; Kidney Disea | 1995 |
Effects of dietary n-3 fatty acid supplementation versus thromboxane synthetase inhibition on gentamicin-induced nephrotoxicosis in healthy male dogs.
Topics: Animals; Body Weight; Creatinine; Diet; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Eating | 1996 |
Limitations in the 'area under the curve' method for predicting daily doses of gentamicin.
Topics: Anti-Bacterial Agents; Computer Simulation; Gentamicins; Infusions, Parenteral; Kidney Diseases | 1996 |
Studies of renal injury. I. Gentamicin toxicity and expression of basolateral transporters.
Topics: Animals; Carrier Proteins; Cell Membrane; Gentamicins; Glucose Transporter Type 1; Isoenzymes; Kidne | 1996 |
Gentamicin nephrotoxicity in the rat: influence of age and diabetes mellitus.
Topics: Aging; Animals; Anti-Bacterial Agents; Body Weight; Copper; Diabetes Mellitus, Experimental; Gentami | 1996 |
Effects of fasting on temporal variations in nephrotoxicity of gentamicin in rats.
Topics: Animals; Anti-Bacterial Agents; Body Weight; Drinking; Eating; Fasting; Female; Gentamicins; Immunoh | 1996 |
Temporal variation in nephrotoxicity of low doses of isepamicin in rats.
Topics: Animals; Anti-Bacterial Agents; Body Weight; Circadian Rhythm; Gentamicins; Immunohistochemistry; In | 1996 |
Aminoglycoside prescription, therapeutic monitoring and nephrotoxicity at a university hospital in Saudi Arabia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Child; Child, Preschool | 1996 |
Effect of superoxide dismutase treatment on gentamicin nephrotoxicity in rats.
Topics: Animals; Anti-Bacterial Agents; Gentamicins; Glutathione; Kidney; Kidney Diseases; Kidney Function T | 1996 |
Attenuation of gentamicin-induced nephrotoxicity in rats by fleroxacin.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Blood Urea Nitrogen; Creatinine; Female; Fler | 1997 |
Time-restricted feeding schedules modify temporal variation of gentamicin experimental nephrotoxicity.
Topics: Analysis of Variance; Animals; Anti-Bacterial Agents; Circadian Rhythm; Drug Evaluation, Preclinical | 1997 |
Renal catabolism of advanced glycation end products: the fate of pentosidine.
Topics: Animals; Anti-Bacterial Agents; Arginine; Chromatography, High Pressure Liquid; Gentamicins; Glycati | 1998 |
In vitro demonstration of a mitogenic activity in renal tissue extracts during regenerative hyperplasia.
Topics: Animals; Antibodies; Cell Division; Cell Line; DNA; Female; Gentamicins; Hyperplasia; Insulin-Like G | 1998 |
Protective effect of ceftriaxone against the nephrotoxicity of isepamicin administered once daily in rats.
Topics: Animals; Anti-Bacterial Agents; Ceftriaxone; Cephalosporins; Creatinine; Gentamicins; Hexosaminidase | 1998 |
Perinephric abscess (presenting as abdominal pain) due to Listeria monocytogenes.
Topics: Abdominal Pain; Abscess; Ampicillin; Child, Preschool; Gentamicins; Humans; Kidney Diseases; Listeri | 1998 |
Enzymes in urine as markers of nephrotoxicity of cytostatic agents and aminoglycoside antibiotics.
Topics: Anti-Bacterial Agents; Antineoplastic Agents; Bacterial Infections; Chromatography, Ion Exchange; Ci | 1998 |
Chronopharmacokinetics and calcium in the prevention of gentamicin-induced nephrotoxicity in rabbits.
Topics: Animals; Calcium Channel Blockers; Calcium Chloride; Drug Interactions; Gentamicins; Injections, Int | 1998 |
Expression of the heat shock protein 47 in gentamicin-treated rat kidneys.
Topics: Actins; Animals; Anti-Bacterial Agents; Collagen; Disease Progression; Gentamicins; Heat-Shock Prote | 1998 |
Risk factors for toxicity in elderly patients given aminoglycosides once daily.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Chi-Square Distribution; Creatinine; Female; Gentami | 1998 |
Development of bone marrow erythroblastic islands in hypoxic rats with intact or damaged kidney tubules.
Topics: Animals; Bone Marrow; Creatinine; Erythroblasts; Erythropoietin; Gentamicins; Hypoxia; Kidney Diseas | 1998 |
Protective effects of vitamin e and probucol against gentamicin-induced nephrotoxicity in rats.
Topics: Acetylglucosaminidase; Animals; Anticholesteremic Agents; Creatinine; Drug Synergism; gamma-Glutamyl | 1999 |
Toxicity of single daily dose gentamicin in stem cell transplantation.
Topics: Adult; Cisplatin; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gentamicin | 1999 |
Renal dysfunction associated with the perioperative use of diclofenac.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Contrast Media; Creatinine; | 1999 |
Central role for interferon-gamma receptor in the regulation of renal MHC expression.
Topics: Adjuvants, Immunologic; Animals; Antigens, Neoplasm; Gene Expression; Gentamicins; Histocompatibilit | 2000 |
Temporal modulation of nephrotoxicity, feeding, and drinking in gentamicin-treated rats.
Topics: Animals; Anti-Bacterial Agents; Creatinine; Diet; Drinking Behavior; Eating; Enzymes; Feeding Behavi | 2000 |
Nephrotoxicity by dicloxacillin and gentamicin in 163 patients with intertrochanteric hip fractures.
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Creatinine; Dicloxaci | 2000 |
Ginkgo biloba extract ameliorates gentamicin-induced nephrotoxicity in rats.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Antioxidants; Disease Models, Animal; Gentamic | 2000 |
A multicenter evaluation of gentamicin therapy in the neonatal intensive care unit.
Topics: Anti-Bacterial Agents; Gentamicins; Humans; Infant, Newborn; Intensive Care Units, Neonatal; Kidney | 2001 |
Individualized pharmacokinetic monitoring results in less aminoglycoside-associated nephrotoxicity and fewer associated costs.
Topics: Anti-Bacterial Agents; Case-Control Studies; Creatinine; Economics, Pharmaceutical; Female; Gentamic | 2001 |
Renal phenotype of low kallikrein rats.
Topics: Angiotensin Receptor Antagonists; Animals; Anti-Bacterial Agents; Blood Volume; Body Weight; Gentami | 2001 |
Effect of dimethyl sulfoxide on gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Anti-Bacterial Agents; Creatinine; Dimethyl Sulfoxide; Dose-Response Relationship, Drug; Dr | 2001 |
Effect of high dietary cholesterol on gentamicin-induced nephrotoxicity in rabbits.
Topics: Alkaline Phosphatase; Animals; Anti-Bacterial Agents; Cholesterol, Dietary; Creatinine; Drug Synergi | 2001 |
Effect of trapidil, an antiplatelet and vasodilator agent on gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Creatinine; Dose-Response Relationship, Drug; Female; Gentamicins; Kidney; Kidney Diseases; | 2001 |
The effect of fosfomycin on glycopeptide antibiotic-induced nephrotoxicity in rats.
Topics: Acetylglucosaminidase; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Drug Therap | 2001 |
[The role of bFGF in renal tubular injury and the interstitial lesion].
Topics: Animals; Cell Division; Epithelial Cells; Female; Fibroblast Growth Factor 2; Fibroblasts; Gentamici | 2000 |
Gentamicin dosing recommendations.
Topics: Bacterial Infections; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Gentam | 2000 |
Risk factors for nephrotoxicity in elderly patients receiving once-daily aminoglycosides.
Topics: Adult; Aged; Aged, 80 and over; Amikacin; Anti-Bacterial Agents; Bacterial Infections; Creatinine; D | 2002 |
Therapeutic implications of gentamicin accumulation in severly diseased kidneys.
Topics: Animals; Dehydration; Dogs; Gentamicins; Glomerulonephritis; Humans; Hydrogen-Ion Concentration; Kid | 1976 |
Comparison of the intrarenal disposition of tobramycin and gentamicin: therapeutic and toxicologic answers.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Dogs; Gentamicins; Humans; Hydrogen-Ion Concentrati | 1978 |
Urinary myelin figures in gentamicin nephrotoxicity.
Topics: Cell Membrane; Fabry Disease; Gentamicins; Humans; Kidney Diseases; Urine | 1979 |
Experimental aminoglycoside nephrotoxicity.
Topics: alpha-L-Fucosidase; Aminoglycosides; Animals; Blood Urea Nitrogen; Gentamicins; Hexosaminidases; Inc | 1975 |
[Study of the cochleo-vestibular tolerance of several antibiotics of the aminoglycoside group].
Topics: Aminoglycosides; Cochlea; Drug Tolerance; Gentamicins; Hearing Disorders; Humans; Kidney; Kidney Dis | 1978 |
Vestibular toxicity of gentamicin in the presence of renal disease.
Topics: Gentamicins; Humans; Kidney Cortex; Kidney Diseases; Labyrinth Diseases; Renal Dialysis; Vestibule, | 1978 |
Transplantation of infected kidneys: clinical and experimental results.
Topics: Animals; Dogs; Dose-Response Relationship, Drug; Escherichia coli Infections; Female; Gentamicins; H | 1979 |
Tetracycline-induced aplastic anemia.
Topics: Anemia, Aplastic; Cephalothin; Gentamicins; Humans; Kidney Diseases; Male; Middle Aged; Proteus Infe | 1979 |
[Nephrotoxic effects of gentamicin in patients with damaged kidneys (author's transl)].
Topics: Adult; Aged; Bacterial Infections; Female; Gentamicins; Humans; Kidney Diseases; Male; Middle Aged | 1979 |
The pathology of nephrotoxicity of gentamicin in snakes. A model for reptilian gout.
Topics: Animals; Animals, Zoo; Gentamicins; Gout; Kidney Diseases; Kidney Tubules, Proximal; Liver; Snakes | 1979 |
Comparative nephrotoxicities of gentamicin, netilmicin and tobramycin in the rat.
Topics: Animals; Anti-Bacterial Agents; Blood Urea Nitrogen; Body Weight; Creatinine; Gentamicins; Kidney; K | 1979 |
Comparative nephrotoxicity of SCH 21420 and amikacin in rats.
Topics: Amikacin; Animals; Creatinine; Enzymes; Gentamicins; Kanamycin; Kidney Diseases; Male; Proteinuria; | 1979 |
Antibacterial activities, nephrotoxicity, and ototoxicity of a new aminoglycoside, Win 42122-2.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Ataxia; Bacteria; Cats; Gentamicins; Guin | 1979 |
[Experimental study on the renal compatibility of the aminoglycosides gentamicin B and O-2-amino-2-deoxy-6-C-methyl-alpha-D-glucopyranosyl-(1 greater than 4)-garamine (G-418)].
Topics: Animals; Enzymes; Female; Gentamicins; Kidney Diseases; Proteinuria; Rats | 1979 |
Investigations on the potential nephrotoxicity of cefazedone and gentamicin and of their combination, in comparison with the combination of cefazolin and cephalothin with gentamicin.
Topics: Adolescent; Adult; Alanine; Aminopeptidases; Cefazolin; Cephalosporins; Cephalothin; Creatinine; Dru | 1979 |
[Netilmicin and tobramycin: comparative evaluation of pharmacokinetics, nephrotoxicity, and therapeutic efficacy in animal studies (author's transl)].
Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Female; Gentamicins; Kidney Diseases; Kinetics | 1979 |
Renal handling of gentamicin and other antibiotics by the isolated perfused rat kidney: mechanism of nephrotoxicity.
Topics: Amiloride; Animals; Cephaloridine; Drug Interactions; Gentamicins; In Vitro Techniques; Kidney; Kidn | 1977 |
The pharmacology of newer aminoglycosides, with a consideration of the application to clinical situations.
Topics: Aminoglycosides; Animals; Anti-Bacterial Agents; Dogs; Gentamicins; Humans; Kidney Diseases; Tobramy | 1977 |
[Renal toxicity of the association: gentamicin/furosemide. One case (author's transl)].
Topics: Adult; Drug Therapy, Combination; Furosemide; Gentamicins; Hepatitis B; Humans; Kidney Diseases; Liv | 1978 |
Dosage schedule of gentamicin for chronic renal insufficiency in children.
Topics: Adolescent; Bacterial Infections; Child; Creatinine; Drug Administration Schedule; Gentamicins; Half | 1978 |
Netilmicin treatment of serious infections in patients with renal insufficiency.
Topics: Aged; Bacterial Infections; Gentamicins; Humans; Kidney; Kidney Diseases; Middle Aged; Sisomicin | 1978 |
Clinical evaluation of aminoglycoside toxicity: tobramycin versus gentamicin, a preliminary report.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Child; Gentamicins; Half-Life; Hearing Disorders; Hu | 1978 |
Gentamicin and tobramycin in patients with various infections--concentrations in serum and urinary excretion.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Female; Gentamicins; Humans; Kidney Diseas | 1978 |
Gentamicin and tobramycin in patients with various infections--nephrotoxicity.
Topics: Aged; Anti-Bacterial Agents; Bacterial Infections; Creatinine; Gentamicins; Humans; Kidney Diseases; | 1978 |
Nephrotoxicity of gentamicin and tobramycin given once daily or continuously in dogs.
Topics: Animals; Anti-Bacterial Agents; Creatinine; Dogs; Drug Administration Schedule; Female; Gentamicins; | 1978 |
Clinico-pharmacological studies of sisomicin in ill children.
Topics: Adolescent; Child; Child, Preschool; Enterobacteriaceae Infections; Gentamicins; Humans; Infant; Inf | 1978 |
Pharmacology and efficacy of netilmicin.
Topics: Adult; Aged; Enterobacteriaceae Infections; Female; Gentamicins; Hearing Disorders; Humans; Kidney D | 1978 |
A model for the prospective identification of the prenephrotoxic state during gentamicin therapy.
Topics: Adult; Aged; Gentamicins; Humans; Kidney Diseases; Kinetics; Middle Aged; Models, Biological | 1978 |
Aminoglycoside and cephalosporin toxicity.
Topics: Anti-Bacterial Agents; Cephalosporins; Drug Therapy, Combination; Gentamicins; Humans; Kidney Diseas | 1978 |
Functional nephrotoxicity of gentamicin in the rat.
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Blood Urea Nitrogen; Carbohydrate Metabolism; Enzymes; | 1978 |
Prediction of gentamicin serum levels using a one-compartment open linear pharmacokinetic model.
Topics: Adult; Aged; Evaluation Studies as Topic; Female; Gentamicins; Half-Life; Hematocrit; Humans; Kidney | 1978 |
Gentamicin-cephalothin drug reaction.
Topics: Adult; Cephalothin; Creatinine; Drug Interactions; Gentamicins; Humans; Kidney Diseases; Male | 1978 |
Pharmacokinetics of netilmicin in patients with renal impairment and in patients on dialysis.
Topics: Adult; Aged; Female; Gentamicins; Half-Life; Humans; Kidney Diseases; Male; Middle Aged; Netilmicin; | 1978 |
Aminoglycosides in patients with impaired renal function.
Topics: Aminoglycosides; Gentamicins; Graft Rejection; Humans; Kidney Diseases | 1978 |
Netilmicin therapy of serious Gram-negative bacillary infections.
Topics: Adult; Aged; Drug Resistance, Microbial; Enterobacteriaceae Infections; Gentamicins; Humans; Kidney | 1978 |
Myeloid bodies in the renal tubules of humans: relationship to gentamicin therapy.
Topics: Adolescent; Adult; Aged; Biopsy; Child; Female; Gentamicins; Humans; Kidney Diseases; Kidney Tubules | 1978 |
Drug-induced lysosomal changes and nephrotoxicity in rats.
Topics: Animals; Anti-Bacterial Agents; Cephacetrile; Cephaloridine; Cephalothin; Female; Gentamicins; Kidne | 1978 |
Enflurane nephrotoxicity and pre-existing renal dysfunction.
Topics: Anesthesia, Inhalation; Animals; Blood Urea Nitrogen; Cell Nucleus; Creatinine; Enflurane; Fluorides | 1978 |
Renal accumulation of amikacin, tobramycin and gentamycin in the rat.
Topics: Amikacin; Animals; Anti-Bacterial Agents; Dose-Response Relationship, Drug; Female; Gentamicins; Kan | 1978 |
Gentamicin nephrotoxicity.
Topics: Gentamicins; Humans; Kidney Diseases | 1978 |
Bacterial renal infection in rats produced by direct injection of bacteria into renal tissue--an experimental model.
Topics: Animals; Disease Models, Animal; Escherichia coli Infections; Female; Gentamicins; Kidney; Kidney Di | 1975 |
Predictability of blood levels of gentamicin in man.
Topics: Adolescent; Adult; Aged; Bacillus subtilis; Cephalothin; Creatinine; Dose-Response Relationship, Dru | 1975 |
Tobramycin in the treatment of severe and complicated urinary tract infections.
Topics: Adult; Aged; Anti-Bacterial Agents; Bacteria; Drug Resistance, Microbial; Female; Gentamicins; Human | 1976 |
Septic arthritis in rheumatoid disease.
Topics: Gentamicins; Humans; Kidney Diseases; Staphylococcal Infections | 1977 |
Hypocalcemia with hypoparathyroidism and renal tubular dysfunction associated with aminoglycoside therapy.
Topics: Adult; Aged; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Doxorubi | 1977 |
Gram-negative sepsis: part II. Management.
Topics: Acidosis; Adult; Amikacin; Child; Chloramphenicol; Clindamycin; Disseminated Intravascular Coagulati | 1977 |
Gentamicin concentrations in blood, urine, and renal tissue of patients with end-stage renal disease.
Topics: Adult; Aged; Female; Gentamicins; Humans; Kidney; Kidney Cortex; Kidney Diseases; Kidney Medulla; Ma | 1977 |
Nephrotoxicity in combined cephalothin and gentamicin therapy.
Topics: Adolescent; Adult; Aged; Cephalothin; Creatinine; Female; Gentamicins; Humans; Kidney; Kidney Diseas | 1977 |
Comparison of the nephrotoxicity of netilmicin and gentamicin in rats.
Topics: Animals; Female; Gentamicins; Kidney; Kidney Diseases; Organ Size; p-Aminohippuric Acid; Rats; Sisom | 1977 |
Nephrotoxicity of cephalosporin-gentamicin combinations in rats.
Topics: Animals; Cephalosporins; Drug Combinations; Enzymes; Gentamicins; Kidney; Kidney Diseases; Kidney Fu | 1976 |
Radioimmunoassay as an improved method for measurement of serum levels of gentamicin.
Topics: Animals; Anti-Bacterial Agents; Antibodies; Biological Assay; Creatinine; Cross Reactions; Gentamici | 1976 |
Gentamicin-induced nephropathy.
Topics: Adolescent; Age Factors; Creatinine; Gentamicins; Humans; Injections, Intramuscular; Kidney Diseases | 1976 |
[Nephrotoxicity of combined therapy with cephalothin and gentamicin].
Topics: Adult; Aged; Cephalothin; Drug Therapy, Combination; Female; Gentamicins; Humans; Infections; Kidney | 1976 |
Methoxyflurane nephropathy.
Topics: Age Factors; Animals; Child; Dose-Response Relationship, Drug; Fluorides; Gentamicins; Humans; Kidne | 1976 |
[Ototoxicity of the aminoglycoside antibiotics (author's transl)].
Topics: Acid Phosphatase; Alkaline Phosphatase; Amikacin; Animals; Anti-Bacterial Agents; Child; Ear, Inner; | 1976 |
Editorial: Gentamicin, cephalothin and poly-antibiotic therapy.
Topics: Cephalothin; Drug Synergism; Drug Therapy, Combination; Gentamicins; Humans; Kidney Diseases | 1975 |
Letter: Gentamicin and cephalothin nephrotoxicity.
Topics: Cephalothin; Drug Therapy, Combination; Gentamicins; Humans; Kidney; Kidney Diseases | 1975 |
Proceedings: Evidence of gentamicin nephrotoxicity in patients with renal allografts.
Topics: Animals; Gentamicins; Graft Rejection; Humans; Kidney Diseases; Kidney Transplantation; Male; Rats; | 1975 |
Evidence of gentamicin nephrotoxicity in patients with renal allografts.
Topics: Acetylglucosaminidase; Alkaline Phosphatase; Anti-Infective Agents; Biopsy; Creatinine; Galactosidas | 1975 |
Acquiescent renal infection.
Topics: Animals; Escherichia coli Infections; Female; Gentamicins; Immunity; Kidney; Kidney Concentrating Ab | 1975 |
[Kidney lesions following treatment with cephalothin and gentamicin].
Topics: Aged; Cephalothin; Gentamicins; Humans; Kidney Diseases; Middle Aged | 1975 |
The diagnostic value of enzymuria, cell excretion, and proteinuria in experimental renal diseases.
Topics: Animals; Clinical Enzyme Tests; Enzymes; Female; Gentamicins; Humans; Kidney Diseases; Kidney Tubula | 1975 |
Enzymuria in gentamicin-induced kidney damage.
Topics: Animals; Enzymes; Gentamicins; Kidney Diseases; Male; Rats; Time Factors | 1975 |
Gentamicin nephrotoxicity: failure of three cephalosporins to potentiate injury in rats.
Topics: Animals; Cephalosporins; Drug Synergism; Drug Therapy, Combination; Female; Gentamicins; Kidney; Kid | 1975 |
[Experimental study in rats on the renal compatibility of cephalothin and cephalothin-aminoglycoside combinations (author's transl)].
Topics: Aminoglycosides; Animals; Aspartate Aminotransferases; Cephalothin; Drug Combinations; Female; Genta | 1975 |
Pharmacokinetic analysis of gentamicin dosage regimens recommended for renal impairment.
Topics: Adult; Creatinine; Drug Administration Schedule; Female; Gentamicins; Half-Life; Humans; Infusions, | 1975 |
Gentamycin in the treatment of urinary tract infection in patients with normal and impaired renal functions.
Topics: Bacteriuria; Female; Gentamicins; Humans; Kidney Diseases; Male | 1975 |
Clinical pharmacology of antibiotic therapy.
Topics: Aminoglycosides; Amoxicillin; Ampicillin; Anti-Bacterial Agents; Carbenicillin; Cephalexin; Cephalor | 1976 |
[The dangers of antibiotic therapy in gram-negative pathogens (author's transl)].
Topics: Acute Kidney Injury; Adult; Anuria; Bacterial Infections; Deafness; Drug Therapy, Combination; Femal | 1976 |
Protective effect of cephalothin against gentamincin-induced nephrotoxicity in rats.
Topics: Animals; Cephalothin; Drug Synergism; Gentamicins; Kidney; Kidney Diseases; Male; Rats; Rats, Inbred | 1976 |
Association of renal injury with combined cephalothin-gentamicin therapy among patients severely ill with malignant disease.
Topics: Bacterial Infections; Cephalothin; Drug Synergism; Drug Therapy, Combination; Gentamicins; Humans; K | 1976 |
Renal damage caused by gentamicin: a study of the effects on renal morphology and urinary enzyme excretion.
Topics: Acetylglucosaminidase; Alkaline Phosphatase; Animals; Galactosidases; Gentamicins; Kidney; Kidney Di | 1976 |
Effect of sodium intake on gentamicin nephrotoxicity in the rat.
Topics: Animals; Gentamicins; Kidney Cortex; Kidney Diseases; Kidney Tubules, Proximal; Male; Rats; Sodium | 1976 |
Pipemidic acid: its activities against various experimental infections.
Topics: Ampicillin; Animals; Anti-Infective Agents; Bacterial Infections; Carbenicillin; Cephalexin; Female; | 1976 |
The use of sodium dodecyl sulfate-polyacrylamide gel electrophoresis to detect renal damage in Sprague-Dawley rats treated with gentamicin sulfate.
Topics: Acetylglucosaminidase; Animals; Blood Urea Nitrogen; Creatinine; Dose-Response Relationship, Drug; E | 1992 |
Aminoglycoside antibiotics alter the electrogenic transport properties of cultured human proximal tubule cells.
Topics: Adult; Anti-Bacterial Agents; Biological Transport, Active; Cells, Cultured; Child, Preschool; Colfo | 1992 |
Comparison of methods for prediction of nephrotoxicity during development.
Topics: Aging; Amikacin; Animals; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Ge | 1992 |
Enzymuria in neonates receiving continuous intravenous infusion of gentamicin.
Topics: Acetylglucosaminidase; Aminopeptidases; CD13 Antigens; Female; Gentamicins; Humans; Infant, Newborn; | 1992 |
Verapamil increases the nephrotoxic potential of gentamicin in rats.
Topics: Animals; Blood Urea Nitrogen; Body Weight; Creatinine; Drug Interactions; Gentamicins; Injections, I | 1992 |
Gentamicin nephrotoxicity in rat: some biochemical correlates.
Topics: Amine Oxidase (Copper-Containing); Animals; Body Weight; Creatinine; Dose-Response Relationship, Dru | 1992 |
Epidermal growth factor accelerates renal tissue repair in a model of gentamicin nephrotoxicity in rats.
Topics: Animals; Cell Division; DNA; Epidermal Growth Factor; Female; Gentamicins; Kidney; Kidney Cortex; Ki | 1992 |
Duration of the protective effect of polyaspartic acid on experimental gentamicin nephrotoxicity.
Topics: Animals; Creatinine; Drug Administration Schedule; Gentamicins; Kidney Diseases; Male; Nephrons; Pep | 1992 |
[Assessment of 99mTc-DMSA renography and uptake compared with creatinine clearance in rats with drug-induced nephrotoxicity--I. Gentamicin-induced nephrotoxicity].
Topics: Animals; Creatinine; Gentamicins; Kidney; Kidney Diseases; Kidney Function Tests; Organotechnetium C | 1991 |
Some pharmacokinetic and pharmacodynamic interactions between digoxin and gentamicin.
Topics: Animals; Calcium; Chinchilla; Digoxin; Drug Interactions; Gentamicins; Iodine Radioisotopes; Kidney | 1991 |
Effects of dextran sulphate on renal dysfunctions induced by gentamicin as determined by the kidney perfusion technique in rats.
Topics: Animals; Blood Glucose; Dextran Sulfate; Gentamicins; Glomerular Filtration Rate; In Vitro Technique | 1991 |
Effect of diet on gentamicin-induced nephrotoxicosis in horses.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Creatinine; Edible Grain; gamma-Gl | 1991 |
Inhibition of aminoglycoside-induced nephrotoxicity in rats by polyanionic peptides.
Topics: Animals; Anions; Female; Gentamicins; Hydrogen-Ion Concentration; Kidney Diseases; Peptides; Polyglu | 1990 |
The sojourn time and its use in pharmacology.
Topics: Aztreonam; Blood Pressure; Gentamicins; Half-Life; Humans; Kidney Diseases; Models, Biological; Nore | 1991 |
Gentamicin nephropathy and contrast media. A comparison between diatrizoate and iohexol in rats.
Topics: Acetylglucosaminidase; Albuminuria; Animals; Diatrizoate; gamma-Glutamyltransferase; Gentamicins; Gl | 1990 |
Polyaspartic acid protects against gentamicin-induced toxicity: mechanism of action.
Topics: Acetylglucosaminidase; Aminopeptidases; Animals; CD13 Antigens; Cells, Cultured; Gentamicins; Kidney | 1990 |
[Nephrotoxicity of aminoglycosides. I: Preventive intraperitoneal calcium administration].
Topics: Animals; Calcium; Creatinine; Gentamicins; Injections, Intraperitoneal; Kidney Diseases; Male; Rats; | 1991 |
[Nephrotoxicity of aminoglycosides. II. Preventive studies with oral administration of verapamil].
Topics: Administration, Oral; Animals; Gentamicins; Kidney Diseases; Male; Rats; Rats, Inbred Strains; Verap | 1991 |
[Nephrotoxicity of aminoglycosides. III. Preventive studies with subcutaneous administration of converting enzyme inhibitor, captopril].
Topics: Animals; Captopril; Gentamicins; Injections, Subcutaneous; Kidney Diseases; Male; Rats; Rats, Inbred | 1991 |
Aminoglycoside toxicity following antibiotic prophylaxis in cardiac surgery.
Topics: Aged; Anti-Bacterial Agents; Bacterial Infections; Cardiac Surgical Procedures; Creatine; Gentamicin | 1990 |
Influence of exogenous protease inhibitor (Bowmann-Birk inhibitor) in gentamicin-induced nephrotoxicity in rats.
Topics: Animals; Female; Gentamicins; Glomerular Filtration Rate; Kidney Diseases; Necrosis; Proteinuria; Ra | 1990 |
[The effects of free radicals in experimental gentamicin nephrotoxicity].
Topics: Animals; Blood Urea Nitrogen; Free Radicals; Gentamicins; Kidney; Kidney Diseases; Lipid Peroxides; | 1990 |
Monitoring of aminoglycosides.
Topics: Anti-Bacterial Agents; Gentamicins; Humans; Kidney Diseases | 1990 |
Cell culture in nephrotoxicity testing.
Topics: Animals; Cells, Cultured; Cytological Techniques; Gentamicins; Kidney; Kidney Diseases; Models, Biol | 1990 |
Extrahepatic cholestasis as a distinct factor predisposing to gentamicin nephrotoxicity.
Topics: Cholestasis, Extrahepatic; Gentamicins; Humans; Kidney; Kidney Diseases; Risk Factors | 1990 |
Extracellular DNA in blood and urine as a potential marker for cytotoxicity and nephrotoxicity in the mouse.
Topics: Animals; Biomarkers; Cell Survival; DNA; Extracellular Space; Female; Gentamicins; Kidney Diseases; | 1990 |
Prolonged endotoxemia enhances the renal injuries induced by gentamicin in rats.
Topics: Animals; Body Weight; Drug Synergism; Endotoxins; Female; Gentamicins; Hematocrit; Kidney; Kidney Co | 1990 |
A Bartter's-like syndrome from capreomycin, and a similar gentamicin tubulopathy.
Topics: Adult; Alkalosis; Bartter Syndrome; Capreomycin; Electrolytes; Gentamicins; Humans; Hyperaldosteroni | 1986 |
Nitrendipine protects against aminoglycoside nephrotoxicity in the rat.
Topics: Acetylglucosaminidase; Aminoglycosides; Animals; Anti-Bacterial Agents; Gentamicins; Kidney Cortex; | 1987 |
Comparative assessment of poly-L-aspartic and poly-L-glutamic acids as protectants against aminoglycoside-induced nephrotoxicity.
Topics: Animals; Anti-Bacterial Agents; Gentamicins; Kidney Diseases; Lysosomes; Peptides; Phospholipids; Po | 1989 |
Bilateral renal cortical abscesses in a young woman with type 1 diabetes.
Topics: Abscess; Adult; Cephradine; Ciprofloxacin; Cloxacillin; Diabetes Mellitus, Type 1; Drug Therapy, Com | 1989 |
Modulation of gentamicin nephrotoxicity by chronic inhibition of angiotensin-I-converting enzyme in rat.
Topics: Acetylglucosamine; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium; Creatinine; Cyclic AM | 1989 |
Inability of nitrendipine to protect against gentamicin nephrotoxicity in the rat.
Topics: Animals; Gentamicins; Kidney Cortex; Kidney Diseases; Male; Nitrendipine; Phospholipids; Rats; Rats, | 1989 |
Effect of age and renal function on gentamicin pharmacokinetic parameters.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aging; Creatinine; Female; Gentamicins; Humans; Kidney D | 1989 |
Effect of glucarolactam on low-dose nephrotoxicities of dibekacin and gentamicin in Fischer rats.
Topics: Animals; Body Weight; Creatinine; Dibekacin; Gentamicins; Glucaric Acid; Kanamycin; Kidney; Kidney D | 1989 |
Comparative nephrotoxicity of ribostamycin and gentamicin in rats evaluated by urinalysis.
Topics: Animals; Anti-Bacterial Agents; Enzymes; Gentamicins; Kidney; Kidney Cortex; Kidney Diseases; Kidney | 1989 |
Gentamicin pharmacokinetics, nephrotoxicity, and prediction of mortality in febrile neutropenic patients.
Topics: Agranulocytosis; Creatinine; Female; Fever; Gentamicins; Half-Life; Humans; Kidney Diseases; Male; M | 1989 |
Enhanced gentamicin nephrotoxicity after experimental biliary obstruction in rats.
Topics: Animals; Cholestasis; Gentamicins; Kidney; Kidney Diseases; Kidney Tubular Necrosis, Acute; Liver Fu | 1989 |
Beta-2-microglobulin excretion in neonates treated with gentamicin.
Topics: beta 2-Microglobulin; Biomarkers; Gentamicins; Humans; Infant, Newborn; Kidney Diseases; Metabolic C | 1989 |
[Experimental study of nephrotoxicity: effects, on the newborn rat kidney, of aminoglycoside administration during gestation].
Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Dibekacin; Female; Gentamicins; Kidney; Kidney Dis | 1989 |
Clinical assessment of a published model to predict aminoglycoside-induced nephrotoxicity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Creatinine; Female; Gentamicins; Half-Life; Humans; Kidn | 1989 |
Clinical considerations and costs associated with formulary conversion from tobramycin to gentamicin.
Topics: Bacteria; Costs and Cost Analysis; Drug Resistance, Microbial; Formularies, Hospital as Topic; Genta | 1989 |
Aminoglycoside nephrotoxicity in obstructive jaundice: possible contribution by concomitantly administered corticosteroids.
Topics: Adrenal Cortex Hormones; Animals; Cholestasis; Drug Interactions; Gentamicins; Humans; Kidney Diseas | 1989 |
Population pharmacokinetic study of gentamicin and a Bayesian approach in patients with renal impairment.
Topics: Adult; Aged; Aged, 80 and over; Bayes Theorem; Creatinine; Female; Gentamicins; Humans; Kidney Disea | 1989 |
Prospective audit of aminoglycoside usage in a general hospital with assessments of clinical processes and adverse clinical outcomes.
Topics: Aminoglycosides; Bacterial Infections; Creatinine; Gentamicins; Gram-Negative Bacteria; Hospitals, G | 1989 |
Conservative management of renal carbuncles in children.
Topics: Adolescent; Ampicillin; Carbuncle; Cephalosporins; Child; Drug Therapy, Combination; Enterobacter; E | 1989 |
Role of sodium in the protective effect of ticarcillin on gentamicin nephrotoxicity in rats.
Topics: Animals; Creatinine; Gentamicins; Kidney Diseases; Male; Penicillins; Rats; Rats, Inbred Strains; So | 1989 |
Variability in pharmacokinetic values for gentamicin, tobramycin, and netilmicin in patients with renal insufficiency.
Topics: Adult; Aged; Aged, 80 and over; Bacterial Infections; Gentamicins; Gram-Negative Bacteria; Humans; K | 1989 |
Serial pharmacokinetic dosing of aminoglycosides: a community hospital experience.
Topics: Anti-Bacterial Agents; Gentamicins; Hospitals, Community; Humans; Kidney Diseases; Tobramycin | 1989 |
Urinary gamma-glutamyl transpeptidase activity in dogs with gentamicin-induced nephrotoxicity.
Topics: Animals; Creatinine; Dog Diseases; Dogs; Female; gamma-Glutamyltransferase; Gentamicins; Kidney Dise | 1985 |
Gentamicin nephrotoxicity in extrahepatic cholestasis: modulation by dietary calcium.
Topics: Animals; Calcium; Cholestasis, Extrahepatic; Gentamicins; Kidney Diseases; Male; Rats; Rats, Inbred | 1989 |
[Habekacin: a new aminoglycoside. Study of nephrotoxicity in rats in comparison with gentamicin, netilmicin and amikacin].
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Dibekacin; Female; Gentamicins; Kanamycin | 1988 |
The dissociation between aminoglycoside serum concentrations and nephrotoxicity.
Topics: Acetylglucosaminidase; Aging; Animals; Animals, Newborn; beta 2-Microglobulin; Creatinine; Gentamici | 1988 |
The use of renal tubule fragments isolated from the rat to investigate aspects of gentamicin nephrotoxicity.
Topics: Animals; Gentamicins; Gluconeogenesis; Glucose; In Vitro Techniques; Kidney Diseases; Kidney Tubules | 1986 |
A picture is worth a thousand words.
Topics: Gentamicins; Humans; Hypotension; Kidney Diseases; Liver Diseases; Male; Middle Aged; Physical Exami | 1986 |
Failure of inhibition of lipid peroxidation by vitamin E to protect against gentamicin nephrotoxicity in the rat.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Catalase; Fatty Acids; Gentamicins; Glutathione; Kidne | 1987 |
Protective effect of urinary alkalinization on gentamicin nephrotoxicity in rats.
Topics: Animals; Bicarbonates; Carbon Dioxide; Gentamicins; Kidney Diseases; Male; Random Allocation; Rats; | 1988 |
Experimental gentamicin nephrotoxicity: effect of streptozotocin-induced diabetes.
Topics: Animals; Diabetes Mellitus, Experimental; Diuresis; Gentamicins; Isosorbide; Kidney; Kidney Cortex; | 1985 |
The protective effect of nitrendipine on gentamicin acute renal failure in rats.
Topics: Acute Kidney Injury; Animals; Female; Gentamicins; Hemodynamics; Kidney; Kidney Diseases; Kidney Fun | 1985 |
Effect of renal mass reduction on kidney tissue concentration of gentamycin following a single dose.
Topics: Animals; Creatinine; Gentamicins; Kidney; Kidney Diseases; Male; Nephrectomy; Organ Size; Rats; Rats | 1988 |
Comparison of serum and renal gentamicin concentrations with fractional urinary excretion tests as indicators of nephrotoxicity.
Topics: Animals; Female; Gentamicins; Kidney; Kidney Diseases; Sheep; Sheep Diseases | 1988 |
[Renal disease associated with heroin abuse].
Topics: Adult; Endocarditis, Bacterial; Female; Gentamicins; Glomerulonephritis; Heroin; Humans; Hypertensio | 1988 |
Hypertension and nephrotoxic lesions in rats 1 year after prenatal exposure to gentamicin.
Topics: Animals; Female; Gentamicins; Hypertension; Kidney; Kidney Diseases; Male; Microscopy, Electron; Pre | 1988 |
[Urinary excretion of N-acetyl-beta-D-glucosaminidase (NAG) and its isoenzyme B as a marker of the nephrotoxicity of gentamicin: re-test from an animal model].
Topics: Acetylglucosaminidase; Animals; Female; Gentamicins; Hexosaminidases; Isoenzymes; Kidney; Kidney Dis | 1988 |
Urinary excretion of N-acetyl-glucosaminidase and beta-2-microglobulin as early markers of gentamicin nephrotoxicity in neonates.
Topics: Acetylglucosaminidase; beta 2-Microglobulin; Creatinine; Female; Gentamicins; Hexosaminidases; Human | 1987 |
Gentamicin pharmacokinetics and nephrotoxicity in naturally acquired and experimentally induced disease in dogs.
Topics: Animals; Blood Urea Nitrogen; Creatinine; Dog Diseases; Dogs; Gentamicins; Half-Life; Kidney; Kidney | 1988 |
The effect of dietary protein restriction on high dose gentamicin nephrotoxicity in rats.
Topics: Acetylglucosaminidase; Animals; Body Weight; Creatinine; Dietary Proteins; Gentamicins; Kidney; Kidn | 1988 |
Validation of the use of Bayesian analysis in the optimization of gentamicin therapy from the commencement of dosing.
Topics: Aged; Bayes Theorem; Female; Gentamicins; Humans; Injections, Intravenous; Kidney Diseases; Male; Ma | 1988 |
Gentamicin nephrotoxic effects in the neonate.
Topics: Creatinine; Gentamicins; Humans; Infant, Newborn; Kidney Diseases | 1988 |
Protective effect of piperacillin against nephrotoxicity of cephaloridine and gentamicin in animals.
Topics: Animals; Cephaloridine; Cephalothin; Fosfomycin; Gentamicins; Kidney Cortex; Kidney Diseases; Kidney | 1988 |
Gentamicin dosing strategies for dogs with subclinical renal dysfunction.
Topics: Animals; Dogs; Gentamicins; Kidney Diseases; Nephrectomy | 1987 |
Impact of aminoglycoside serum assays on clinical decisions and renal toxicity.
Topics: Amikacin; Aminoglycosides; Anti-Bacterial Agents; Costs and Cost Analysis; Creatinine; Decision Maki | 1986 |
The influence of single or repeated phlebotomy on the physiological condition of normal and diseased rats.
Topics: Anemia; Animals; Blood Cell Count; Blood Pressure; Bloodletting; Carbon Tetrachloride; Chemical and | 1987 |
Calcium channel blockade in experimental aminoglycoside nephrotoxicity.
Topics: Animals; Calcium; Calcium Channel Blockers; Creatinine; Gentamicins; Kidney; Kidney Diseases; Male; | 1987 |
Dose response studies of gentamicin nephrotoxicity in rats with experimental renal dysfunction. III. Effects of dosage adjustment method.
Topics: Animals; Blood Urea Nitrogen; Creatinine; Dose-Response Relationship, Drug; Gentamicins; Kidney Dise | 1987 |
Gentamicin disposition in young and elderly patients with various degrees of renal function.
Topics: Adult; Aged; Aged, 80 and over; Aging; Creatinine; Gentamicins; Half-Life; Humans; Kidney Diseases; | 1987 |
Experimental cyclosporine nephrotoxicity: risk of concomitant chemotherapy.
Topics: Amphotericin B; Animals; Anti-Infective Agents; Cyclosporins; Drug Interactions; Gentamicins; Ketoco | 1986 |
[Isoenzymes of N-acetyl-beta-D-glucosaminidase (NAG): new method of evaluating the nephrotoxicity of aminosides. Our experience with dibekacin in geriatrics].
Topics: Acetylglucosaminidase; Acute Kidney Injury; Aged; Dibekacin; Female; Gentamicins; Hexosaminidases; H | 1986 |
Exaggerated response to gentamicin-induced nephrotoxicity in Sprague-Dawley rats: identification of a highly sensitive outlier population.
Topics: Animals; Blood Urea Nitrogen; Creatinine; Gentamicins; Kidney Diseases; Kidney Tubules; Kinetics; Ma | 1986 |
[Pharmacokinetics and toxicity of gentamycin in the newborn infant].
Topics: Gentamicins; Half-Life; Hearing Disorders; Humans; Infant, Newborn; Infant, Premature; Kidney Diseas | 1986 |
The role of cell calcium overload in nephrotoxic renal tubular cell injury.
Topics: Animals; Calcium; Gentamicins; Kidney Cortex; Kidney Diseases; Kidney Tubules; Mercuric Chloride; Mi | 1986 |
Effect of parathyroid hormone activity on gentamicin nephrotoxicity.
Topics: Animals; Calcium; Gentamicins; Hypocalcemia; Kidney Diseases; Male; Parathyroid Glands; Parathyroid | 1987 |
Nephrotoxicity of vancomycin-gentamicin therapy in pediatric patients.
Topics: Adolescent; Child; Child, Preschool; Drug Therapy, Combination; Female; Gentamicins; Humans; Infant; | 1987 |
Aminoglycoside monitoring in neonates--a re-appraisal.
Topics: Amikacin; Aminoglycosides; Gentamicins; Humans; Infant, Newborn; Kidney Diseases; Labyrinth Diseases | 1985 |
The predictive value of urinary N-acetyl-beta-D-glucosaminidase in evaluating aminoglycoside nephrotoxicity.
Topics: Acetylglucosaminidase; Adult; Aged; Amikacin; Aminoglycosides; Female; Gentamicins; Hexosaminidases; | 1985 |
Cost effectiveness of gentamicin and tobramycin.
Topics: Cost-Benefit Analysis; Gentamicins; Humans; Kidney Diseases; Renal Dialysis; Tobramycin | 1985 |
[Gentamicin nephropathy in rats and a simple method for its prevention].
Topics: Animals; Creatinine; Drinking; Female; Gentamicins; Isotonic Solutions; Kidney Diseases; Male; Rats; | 1986 |
Aminoglycoside nephrotoxicity and renal function status.
Topics: Aminoglycosides; Anti-Bacterial Agents; Gentamicins; Humans; Kidney Diseases; Tobramycin | 1986 |
Comparative study on renal accumulation of aminoglycoside antibiotics.
Topics: Amikacin; Aminoglycosides; Animals; Anti-Bacterial Agents; Gentamicins; Half-Life; Kidney; Kidney Di | 1985 |
Vancomycin/aminoglycoside nephrotoxicity.
Topics: Adolescent; Aminoglycosides; Anti-Bacterial Agents; Child; Child, Preschool; Drug Therapy, Combinati | 1985 |
Effect of amiloride on experimental gentamicin nephrotoxicity.
Topics: Amiloride; Animals; Diet; Drug Interactions; Gentamicins; Inulin; Kidney; Kidney Cortex; Kidney Dise | 1985 |
Decreased fractional renal excretion of gentamicin in subtotal nephrectomized dogs.
Topics: Absorption; Animals; Dogs; Female; Gentamicins; Kidney; Kidney Diseases; Metabolic Clearance Rate; N | 1985 |
Relationship between rat renal accumulation of gentamicin, tobramycin, and netilmicin and their nephrotoxicities.
Topics: Animals; Gentamicins; Kidney; Kidney Diseases; Kinetics; Male; Netilmicin; Rats; Rats, Inbred Strain | 1985 |
Dose-response studies of gentamicin nephrotoxicity in rats with experimental renal dysfunction. I. Subtotal surgical nephrectomy.
Topics: Absorption; Analysis of Variance; Animals; Gentamicins; Glomerular Filtration Rate; Injections, Subc | 1985 |
[Mycoplasma as the causative agent of kidney infections].
Topics: Adolescent; Adult; Aged; Bacteriuria; Female; Gentamicins; Humans; Kidney Diseases; Male; Middle Age | 1985 |
[Clinical studies of intravenous drip infusion of micronomicin. 1. Pharmacokinetics (Part 2). Intravenous Micronomicin Research Group].
Topics: Adult; Aged; Aminoglycosides; Anti-Bacterial Agents; Female; Gentamicins; Humans; Infusions, Parente | 1985 |
Gentamicin nephropathy in a neonate.
Topics: Gentamicins; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infant, Premature; Kidney Diseases; | 1985 |
Comparative effects of gentamicin and tobramycin on excretion of N-acetyl-beta-D-glucosaminidase.
Topics: Acetylglucosaminidase; Adult; Aged; Creatinine; Gentamicins; Hexosaminidases; Humans; Kidney Disease | 1985 |
[Ototoxicity and nephrotoxicity of gentamicin and tobramycin].
Topics: Creatinine; Female; Gentamicins; Hearing Disorders; Humans; Kidney Diseases; Male; Tobramycin | 1985 |
Clinical and laboratory evidence for inactivation of gentamicin by carbenicillin.
Topics: Adult; Animals; Bacillus subtilis; Child; Chromatography, Thin Layer; Culture Media; Gentamicins; Hu | 1971 |
Antibiotic levels on continuous intravenous infusion.
Topics: Anti-Bacterial Agents; Gentamicins; Half-Life; Humans; Infusions, Parenteral; Kidney; Kidney Disease | 1971 |
Tobramycin therapy in renal failure.
Topics: Adult; Aminoglycosides; Anti-Bacterial Agents; Female; Gentamicins; Humans; Kidney Diseases; Male; M | 1974 |
[Use of getamicin in reconstructive surgery].
Topics: Abscess; Adult; Bacterial Infections; Child; Cholangitis; Empyema; Escherichia coli; Gentamicins; Hu | 1974 |
Enhancement of gentamicin nephrotoxicity by glycerol.
Topics: Animals; Drug Synergism; Gentamicins; Glycerol; Kidney Diseases; Kidney Function Tests; Male; Rats; | 1974 |
[Elimination of antibiotics and sulfonamides from the human organism during renal insufficiency and the therapeutic consequences].
Topics: Ampicillin; Anti-Bacterial Agents; Cephaloridine; Cephalothin; Chloramphenicol; Creatinine; Dicloxac | 1969 |
Untoward effects of antimicrobial agents on major organ systems.
Topics: Agranulocytosis; Amphotericin B; Anemia, Aplastic; Anemia, Hemolytic; Anti-Bacterial Agents; Ataxia; | 1974 |
Letter: Severe combined nephrotoxicity of BL-P1654 and gentamicin.
Topics: Adult; Blood Bactericidal Activity; Carbenicillin; Drug Therapy, Combination; Endocarditis, Bacteria | 1974 |
[Tubulointerstitial nephropathies due to antibiotics].
Topics: Acute Kidney Injury; Anti-Bacterial Agents; Cephalexin; Cephaloridine; Cephalothin; Drug Hypersensit | 1973 |
[Use of analog computer for the study of gentamicin pharmacokinetics in persons with normal or reduced kidney function].
Topics: Computers, Analog; Gentamicins; Humans; Kidney; Kidney Diseases; Kinetics | 1974 |
Individualization of drug dosage in patients with renal disease.
Topics: Creatinine; Gentamicins; Half-Life; Humans; Kidney Diseases; Pharmaceutical Preparations; Statistics | 1974 |
[Treatment of gonorrhea in women using a single gentamicin administration].
Topics: Adolescent; Adult; Child; Cochlea; Drug Evaluation; Drug Tolerance; Female; Gentamicins; Gonorrhea; | 1974 |
Dose regimen of kanamycin and gentamicin.
Topics: Adolescent; Adult; Age Factors; Aged; Arteriosclerosis; Creatinine; Drug Administration Schedule; Fe | 1974 |
[Renal tolerance of gentamicin].
Topics: Animals; Cats; Dogs; Drug Tolerance; Gentamicins; Humans; Kidney Diseases; Necrosis; Rats; Uremia | 1974 |
[Animal experiment investigations on the nephrotoxicity of the cephalothin-gentamicin combination].
Topics: Animals; Cephalothin; Diuresis; Drug Therapy, Combination; Gentamicins; Kidney; Kidney Diseases; Kid | 1974 |
The use of gentamicin intravenously.
Topics: Adolescent; Adult; Aged; Child; Creatinine; Depression, Chemical; Female; Gentamicins; Hearing Disor | 1973 |
Nephropathy associated with methicillin administration.
Topics: Acidosis; Aged; Biopsy; Chlorides; Eosinophilia; Female; Gentamicins; Humans; Immunoglobulins; Kanam | 1974 |
Retrospective study of the ototoxicity of gentamicin.
Topics: Adult; Age Factors; Aged; Creatinine; Dose-Response Relationship, Drug; Electrooculography; Gentamic | 1973 |
Prospective study of the ototoxicity of gentamicin.
Topics: Adult; Age Factors; Aged; Creatinine; Electrooculography; Gentamicins; Hearing Disorders; Humans; Ki | 1973 |
The ototoxicity of gentamicin.
Topics: Age Factors; Aged; Body Temperature; Cochlea; Creatinine; Electrooculography; Female; Gentamicins; H | 1973 |
[Nephrology in 1972].
Topics: Bone Resorption; Calcium; Dextrans; Female; Fluorescent Antibody Technique; Gentamicins; Glomerulone | 1972 |
Gentamicin, tubocurarine, lignocaine and neuromuscular blockade. A case report.
Topics: Aortic Valve; Drug Interactions; Gentamicins; Heart Valve Prosthesis; Humans; Kidney Diseases; Lidoc | 1972 |
Clinical pharmacology of gentamicin in the newborn infant.
Topics: Bacterial Infections; Brain; Gentamicins; Gestational Age; Humans; Infant, Newborn; Infant, Newborn, | 1972 |
[Gentamicin and kidney diseases].
Topics: Bacterial Infections; Gentamicins; Glomerular Filtration Rate; Half-Life; Humans; Kidney; Kidney Dis | 1973 |
[Therapy of severe purulent menigitides].
Topics: Ampicillin; Chlormethiazole; Diazepam; Furosemide; Gentamicins; Humans; Injections, Intravenous; Kid | 1973 |
An animal model for combined methoxyflurane and gentamicin nephrotoxicity.
Topics: Anesthesia; Animals; Blood Urea Nitrogen; Drug Synergism; Fluorides; Gentamicins; Kidney; Kidney Dis | 1973 |
Combined nephrotoxicity of gentamicin and methoxyflurane anaesthesia in man. A case report.
Topics: Anesthesia, Inhalation; Blood Urea Nitrogen; Body Weight; Creatinine; Drug Synergism; Fluorides; Gen | 1973 |
[Side-effects of gentamicin. Report of a case treated for an unusually long period].
Topics: Female; Gentamicins; Humans; Infant; Kidney Diseases; Kidney Failure, Chronic; Time Factors; Urinary | 1973 |
Toxic nephropathies.
Topics: Aspirin; Gentamicins; Humans; Kidney Diseases; Methoxyflurane; Phenacetin | 1973 |
Cephalothin, gentamicin, colistin hazards.
Topics: Cephalothin; Colistin; Drug Synergism; Gentamicins; Humans; Kidney; Kidney Diseases | 1973 |
Unusual renal infections.
Topics: Abscess; Adult; Aged; Cephalosporins; Cephalothin; Drainage; Female; Gentamicins; Humans; Kidney Dis | 1973 |
Letter: Nephrotoxic drugs.
Topics: Animals; Cephaloridine; Cephalothin; Drug Interactions; Gentamicins; Kidney Diseases; Kidney Tubules | 1973 |
[Gentamicin nephropathy].
Topics: Adolescent; Aged; Biopsy; Creatinine; Female; Gentamicins; Humans; Kidney; Kidney Diseases; Kidney F | 1973 |
[Editorial: Gentamicin nephropathy].
Topics: Gentamicins; Humans; Kidney Diseases; Kidney Function Tests | 1973 |
[Letter: Gentamycin-nephropathy].
Topics: Aged; Creatinine; Female; Gentamicins; Humans; Kidney Diseases; Kidney Function Tests; Male; Middle | 1973 |
Diagnosis and treatment of pyelonephritis.
Topics: Ampicillin; Bacterial Infections; Cephalexin; Erythromycin; Female; Gentamicins; Humans; Kidney Dise | 1973 |
Tobramycin and gentamicin concentrations in the serum of normal and anephric patients.
Topics: Aminoglycosides; Anti-Bacterial Agents; Gentamicins; Half-Life; Humans; Kidney; Kidney Diseases; Nep | 1973 |
[The nephrotoxicity of gentamicin, cephalothin and of their combinations in animal experiments].
Topics: Animals; Cephalothin; Creatinine; Drug Combinations; Gentamicins; Kidney; Kidney Diseases; Kidney Gl | 1973 |
Letter: Renal damage caused by gentamicin.
Topics: Animals; Galactosidases; Gentamicins; Hexosaminidases; Humans; Kidney Diseases; Kidney Tubules; Rats | 1974 |
Drug dosage in patients with renal disease.
Topics: Anti-Bacterial Agents; Creatinine; Dosage Forms; Dose-Response Relationship, Drug; Gentamicins; Half | 1974 |
[Clinical experience with the broadspectrum antibiotic gentamycin (1969-1970)].
Topics: Adult; Bronchitis; Bronchopneumonia; Brucellosis; Gentamicins; Humans; Injections, Intramuscular; Ki | 1972 |
[Kinetic specification of some antibiotics in cases with kidney insufficiency].
Topics: Ampicillin; Anti-Bacterial Agents; Carbenicillin; Cephalosporins; Chloramphenicol; Erythromycin; Gen | 1972 |
[Experimental studies on nephrotoxicity of gentamicin].
Topics: Animals; Gentamicins; Kidney; Kidney Diseases; Microscopy, Electron; Mitochondria; Rats; Regeneratio | 1972 |
[Influence of the renal function on the pharmacokinetics of various drugs].
Topics: Anti-Bacterial Agents; Anuria; Colistin; Gentamicins; Glomerular Filtration Rate; Half-Life; Humans; | 1972 |
Serum creatinine and drug half-lives in renal failure.
Topics: Creatinine; Gentamicins; Half-Life; Humans; Kanamycin; Kidney Diseases; Pharmaceutical Preparations | 1972 |
[Arguments against the nephrotoxicity of cephalothin and gentamicin].
Topics: Adolescent; Adult; Aged; Anemia; Cephalothin; Drug Combinations; Female; Gentamicins; Humans; Kidney | 1972 |
[Antibiotic therapy in disturbed kidney function].
Topics: Ampicillin; Anti-Bacterial Agents; Cephaloridine; Cephalothin; Creatinine; Erythromycin; Gentamicins | 1971 |
Ototoxicity of gentamicin in man: a survey and controlled analysis of clinical experience in the United States.
Topics: Adult; Age Factors; Body Weight; Ear, Inner; Gentamicins; Hearing Disorders; Humans; Kidney Diseases | 1971 |
[Study of the nephrotoxicity of gentamicin in humans].
Topics: Adult; Aged; Female; Gentamicins; Humans; Kidney; Kidney Diseases; Kidney Function Tests; Male; Midd | 1971 |
Gentamicin sulphate.
Topics: Animals; Burns; Ear, Inner; Gentamicins; Hearing Disorders; Humans; Kidney Diseases; Pseudomonas Inf | 1968 |
Clinical research experience with gentamicin. Incidence of adverse reactions.
Topics: Deafness; Gentamicins; Hearing Disorders; Humans; Kanamycin; Kidney Diseases; Male; Middle Aged; Neo | 1970 |
Aspects of the chronic toxicity of gentamicin sulfate in cats.
Topics: Animals; Ataxia; Biological Assay; Cats; Gentamicins; Injections, Intra-Arterial; Injections, Subcut | 1971 |
[Use of 8-mercaptoadenine for the prevention of nephrotoxic effects of some antibiotics].
Topics: Acid Phosphatase; Animals; Fats; Gentamicins; Guinea Pigs; Kanamycin; Kidney; Kidney Diseases; Mice; | 1969 |
[Pharmacokinetic studies of gentamycin in children].
Topics: Adolescent; Aminohippuric Acids; Child; Child, Preschool; Female; Gentamicins; Humans; Infant; Infan | 1970 |
Distribution and dosage of antibacterial agents in patients with normal and impaired renal function.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Diffusion; Gentamicins; Humans; Kidney; Kidne | 1970 |