gentamicin has been researched along with Ischemia in 31 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We used our well-established global hypoxia-asphyxia newborn pig model to evaluate the effect of mild hypothermia after hypoxia-ischemia on gentamicin pharmacokinetics." | 7.70 | Influence of mild hypothermia after hypoxia-ischemia on the pharmacokinetics of gentamicin in newborn pigs. ( Hoem, NO; Lindgren, CG; Melby, K; Porter, H; Satas, S; Thoresen, M; Whitelaw, A, 2000) |
| "The main purpose of our study is to investigate the possible protective effects of Fructose 1-6 diphosphate (FDP) and Danshen (Salvia Miltiozzhiza Bunze) on renal cortical Na-K-ATPase activity after renal ischemia and gentamicin nephrotoxicity." | 7.67 | Effects of FDP and Danshen on renal cortical Na-K-ATPase activity in rats after treatment with renal ischemia and gentamicin. ( Lin, SY; Lu, FM, 1989) |
| " Toxicity is dose related, but some patients may still develop hearing loss even under safe dosage." | 5.37 | Transient ischemia/hypoxia enhances gentamicin ototoxicity via caspase-dependent cell death pathway. ( Hsu, CJ; Kao, MC; Lai, CH; Lin, CD; Lin, CW; Lin, CY; Tang, CH; Tsai, MH; Wei, IH, 2011) |
| "The aims of the study were to analyze the penetration of gentamicin in foot ulcers in patients with different severities of peripheral arterial disease (PAD) and to determine significant parameters affecting lower limb tissue concentrations." | 3.77 | Factors affecting gentamicin penetration in lower extremity ischemic tissues with ulcers. ( Azzopardi, LM; Cassar, K; Fiorentino, L; LaFerla, G; Zammit, MC, 2011) |
| "Having shown rapid trafficking of aminoglycosides to the Golgi complex in cell culture, we focused on the injurious interaction that occurs when gentamicin administration is preceded by renal ischemia." | 3.71 | Nucleotide depletion increases trafficking of gentamicin to the Golgi complex in LLC-PK1 cells. ( Bacallao, RL; Dunn, KW; Leiser, JD; Molitoris, BA; Sandoval, RM, 2002) |
| " We used our well-established global hypoxia-asphyxia newborn pig model to evaluate the effect of mild hypothermia after hypoxia-ischemia on gentamicin pharmacokinetics." | 3.70 | Influence of mild hypothermia after hypoxia-ischemia on the pharmacokinetics of gentamicin in newborn pigs. ( Hoem, NO; Lindgren, CG; Melby, K; Porter, H; Satas, S; Thoresen, M; Whitelaw, A, 2000) |
| "The main purpose of our study is to investigate the possible protective effects of Fructose 1-6 diphosphate (FDP) and Danshen (Salvia Miltiozzhiza Bunze) on renal cortical Na-K-ATPase activity after renal ischemia and gentamicin nephrotoxicity." | 3.67 | Effects of FDP and Danshen on renal cortical Na-K-ATPase activity in rats after treatment with renal ischemia and gentamicin. ( Lin, SY; Lu, FM, 1989) |
| "The authors present five cases of severe retinal ischemia associated with gentamicin injection." | 3.67 | Retinal toxicity secondary to intraocular gentamicin injection. ( Allen, AW; Chenoweth, RG; Cohen, HB; Crawford, JB; Klein, R; May, DR; McDonald, HR; Schatz, H; Snider, JD, 1986) |
| "The purpose of this study was to examine the pharmacokinetics of gentamicin renal uptake in dogs and assess the role of chronic renal ischemia." | 3.66 | Renal handling of gentamicin by normal and ischemic canine kidneys. ( Adelman, MH; Harrison, NJ; Schentag, JJ; Wels, PB, 1982) |
| "Deep-space surgical site infections carry significant morbidity and mortality." | 1.72 | Gentamicin-Containing Collagen Implant May Reduce Surgical Site Infections After Open Infrainguinal Arterial Revascularization. ( Garbowski, MW; Hockley, JA; Jacques, A; Jansen, SJ; Kwok, CHR; Stopher, L; Zhao, AH, 2022) |
| " Toxicity is dose related, but some patients may still develop hearing loss even under safe dosage." | 1.37 | Transient ischemia/hypoxia enhances gentamicin ototoxicity via caspase-dependent cell death pathway. ( Hsu, CJ; Kao, MC; Lai, CH; Lin, CD; Lin, CW; Lin, CY; Tang, CH; Tsai, MH; Wei, IH, 2011) |
| "In 2 patients with severe Meniere's disease (MD), there was histologic evidence of occlusion of the vein of the vestibular aqueduct (VVA)." | 1.31 | Vascular occlusion in the endolymphatic sac in Meniere's disease. ( Friberg, U; Rask-Andersen, H, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (38.71) | 18.7374 |
| 1990's | 7 (22.58) | 18.2507 |
| 2000's | 4 (12.90) | 29.6817 |
| 2010's | 7 (22.58) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, AH | 1 |
| Kwok, CHR | 1 |
| Jacques, A | 1 |
| Stopher, L | 1 |
| Hockley, JA | 1 |
| Garbowski, MW | 1 |
| Jansen, SJ | 1 |
| Behera, UC | 1 |
| Singh, A | 1 |
| Jain, L | 1 |
| Desai, A | 1 |
| Cianciolo Cosentino, C | 1 |
| Skrypnyk, NI | 1 |
| Brilli, LL | 1 |
| Chiba, T | 1 |
| Novitskaya, T | 1 |
| Woods, C | 1 |
| West, J | 1 |
| Korotchenko, VN | 1 |
| McDermott, L | 1 |
| Day, BW | 1 |
| Davidson, AJ | 1 |
| Harris, RC | 1 |
| de Caestecker, MP | 1 |
| Hukriede, NA | 1 |
| Wang, E | 1 |
| Sandoval, RM | 3 |
| Campos, SB | 1 |
| Molitoris, BA | 5 |
| Lin, CD | 1 |
| Kao, MC | 1 |
| Tsai, MH | 2 |
| Lai, CH | 1 |
| Wei, IH | 1 |
| Tang, CH | 1 |
| Lin, CW | 1 |
| Hsu, CJ | 1 |
| Lin, CY | 1 |
| Zammit, MC | 1 |
| Fiorentino, L | 1 |
| Cassar, K | 1 |
| Azzopardi, LM | 1 |
| LaFerla, G | 1 |
| Hall, AM | 1 |
| Rhodes, GJ | 1 |
| Corridon, PR | 1 |
| Silachev, DN | 1 |
| Isaev, NK | 1 |
| Pevzner, IB | 1 |
| Zorova, LD | 1 |
| Stelmashook, EV | 1 |
| Novikova, SV | 1 |
| Plotnikov, EY | 1 |
| Skulachev, VP | 1 |
| Zorov, DB | 1 |
| Bacallao, RL | 1 |
| Dunn, KW | 1 |
| Leiser, JD | 1 |
| Agarwal, P | 1 |
| Agrawal, PK | 1 |
| Sharma, D | 1 |
| Baghel, KD | 1 |
| Zager, RA | 1 |
| Sharma, HM | 1 |
| Sufian, S | 1 |
| Katz, SM | 1 |
| Adelman, MH | 2 |
| Harrison, NJ | 1 |
| Wels, PB | 1 |
| Schentag, JJ | 2 |
| Bühler-Singer, S | 1 |
| Hiller, D | 1 |
| Boateng, B | 1 |
| Albrecht, HP | 1 |
| Seidel, C | 1 |
| Hornstein, OP | 1 |
| Grizzard, WS | 1 |
| Calhoun, JH | 1 |
| Klemm, K | 1 |
| Anger, DM | 1 |
| Mader, JT | 1 |
| Cavini-Ferreira, PC | 1 |
| Meyer, C | 1 |
| Dahl, R | 1 |
| Geerdes, A | 1 |
| Wakui, H | 1 |
| Komatsuda, A | 1 |
| Miura, AB | 1 |
| Satas, S | 1 |
| Hoem, NO | 1 |
| Melby, K | 1 |
| Porter, H | 1 |
| Lindgren, CG | 1 |
| Whitelaw, A | 1 |
| Thoresen, M | 1 |
| Friberg, U | 1 |
| Rask-Andersen, H | 1 |
| Chiu, PJ | 1 |
| Long, JF | 1 |
| Spiegel, DM | 1 |
| Shanley, PF | 1 |
| Lu, FM | 1 |
| Lin, SY | 1 |
| Erturk, E | 1 |
| Bretan, P | 1 |
| Pestana, J | 1 |
| Steinmuller, D | 1 |
| Stowe, NT | 1 |
| Novick, AC | 1 |
| Plonka, AJ | 1 |
| Messinger, S | 1 |
| Francis, KL | 1 |
| Williams, JS | 1 |
| Schatz, H | 2 |
| McDonald, HR | 2 |
| Allen, AW | 1 |
| Chenoweth, RG | 1 |
| Cohen, HB | 1 |
| Crawford, JB | 1 |
| Klein, R | 1 |
| May, DR | 1 |
| Snider, JD | 1 |
| Stein, JH | 1 |
| Fried, TA | 1 |
| Cohen, SR | 1 |
| Cornell, CN | 1 |
| Collins, MH | 1 |
| Sell, JE | 1 |
| Blanc, WA | 1 |
| Altman, RP | 1 |
| Barbizet, J | 1 |
| Degos, JD | 1 |
| Hurth, M | 1 |
| Duval, J | 1 |
| Aillerie, MA | 1 |
2 reviews available for gentamicin and Ischemia
| Article | Year |
|---|---|
Heat-shock proteins in animal models for acute renal failure.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Cisplatin; Constriction; | 1995 |
Experimental models of nephrotoxic acute renal failure.
Topics: Acute Kidney Injury; Animals; Capillary Permeability; Cisplatin; Disease Models, Animal; Dogs; Genta | 1985 |
29 other studies available for gentamicin and Ischemia
| Article | Year |
|---|---|
Gentamicin-Containing Collagen Implant May Reduce Surgical Site Infections After Open Infrainguinal Arterial Revascularization.
Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arterial Occlusive Diseases; Diabetes Complications; | 2022 |
Serial Swept-Source Optical Coherence Tomography Features of Gentamicin Macular Toxicity: A Glimpse Into the Injury Cascade.
Topics: Adult; Anti-Bacterial Agents; Gentamicins; Humans; Injections, Intraocular; Ischemia; Macula Lutea; | 2018 |
Histone deacetylase inhibitor enhances recovery after AKI.
Topics: Acute Kidney Injury; Animals; Disease Models, Animal; Fibrosis; Gentamicins; Histone Deacetylase 1; | 2013 |
Rapid diagnosis and quantification of acute kidney injury using fluorescent ratio-metric determination of glomerular filtration rate in the rat.
Topics: Acute Kidney Injury; Algorithms; Animals; Data Interpretation, Statistical; Female; Fluorescein-5-is | 2010 |
Transient ischemia/hypoxia enhances gentamicin ototoxicity via caspase-dependent cell death pathway.
Topics: Animals; Anti-Bacterial Agents; Apoptosis; Blotting, Western; Caspases; Cell Line; Cochlea; Disease | 2011 |
Factors affecting gentamicin penetration in lower extremity ischemic tissues with ulcers.
Topics: Adult; Aged; Aged, 80 and over; Ankle Brachial Index; Anti-Bacterial Agents; Debridement; Diabetes M | 2011 |
In vivo multiphoton imaging of mitochondrial structure and function during acute kidney injury.
Topics: Acute Kidney Injury; Animals; Gentamicins; Glutathione; Ischemia; Kidney; Kidney Tubules, Distal; Ki | 2013 |
The mitochondria-targeted antioxidants and remote kidney preconditioning ameliorate brain damage through kidney-to-brain cross-talk.
Topics: Animals; Antioxidants; Brain; Epithelial Cells; Erythropoietin; Gentamicins; Immunoassay; Infarction | 2012 |
Nucleotide depletion increases trafficking of gentamicin to the Golgi complex in LLC-PK1 cells.
Topics: Animals; Anti-Bacterial Agents; Gentamicins; Golgi Apparatus; Ischemia; Kidney Tubules, Proximal; LL | 2002 |
Intravenous infusion for the treatment of diabetic and ischaemic non-healing pedal ulcers.
Topics: Adult; Case-Control Studies; Debridement; Diabetic Foot; Female; Foot; Foot Ulcer; Gentamicins; Hepa | 2005 |
Gentamicin increases renal susceptibility to an acute ischemic insult.
Topics: Acute Kidney Injury; Animals; Blood Urea Nitrogen; Creatinine; Disease Susceptibility; Electrolytes; | 1983 |
Urinary myelin figures in gentamicin. Treated vs. ischemic kidneys.
Topics: Acute Kidney Injury; Animals; Constriction; Disease Models, Animal; Dogs; Gentamicins; Ischemia; Kid | 1983 |
Renal handling of gentamicin by normal and ischemic canine kidneys.
Topics: Absorption; Animals; Constriction; Disease Models, Animal; Dogs; Gentamicins; Ischemia; Kidney; Kidn | 1982 |
[Disordered cutaneous microcirculation in diabetic neuropathic foot ulcer. Is modification by retrograde transvenous perfusion therapy possible?].
Topics: Adult; Aged; Blood Flow Velocity; Chemotherapy, Cancer, Regional Perfusion; Dexamethasone; Diabetic | 1995 |
Aminoglycoside toxicity in the treatment of endophthalmitis.
Topics: Amikacin; Endophthalmitis; Gentamicins; Humans; Ischemia; Ophthalmic Solutions; Retinal Diseases; Re | 1995 |
Use of antibiotic-PMMA beads in the ischemic foot.
Topics: Anti-Bacterial Agents; Drug Implants; Female; Foot; Foot Diseases; Gentamicins; Humans; Infections; | 1994 |
[Pioneer experience with buflomedil in the form of retrograde venous pulse therapy for treatment of ischemia and severe extremity infections].
Topics: Bacterial Infections; Chemotherapy, Cancer, Regional Perfusion; Dexamethasone; Drug Therapy, Combina | 1993 |
Mechanism of ischemia-enhanced aminoglycoside binding and uptake by proximal tubule cells.
Topics: Aminoglycosides; Animals; Cell Membrane; Gentamicins; Immunohistochemistry; Ischemia; Kidney Tubules | 1993 |
Influence of mild hypothermia after hypoxia-ischemia on the pharmacokinetics of gentamicin in newborn pigs.
Topics: Animals; Animals, Newborn; Blood Glucose; Creatinine; Female; Fluorescence Polarization Immunoassay; | 2000 |
Vascular occlusion in the endolymphatic sac in Meniere's disease.
Topics: Adult; Aged; Anti-Bacterial Agents; Audiometry; Biopsy; Calcinosis; Case-Control Studies; Combined M | 2002 |
Urinary excretion and tissue accumulation of gentamicin and paraaminohippurate in postischemic rat kidneys.
Topics: Aminohippuric Acids; Animals; Gentamicins; Ischemia; Kidney; Male; p-Aminohippuric Acid; Rats | 1979 |
Mild ischemia predisposes the S3 segment to gentamicin toxicity.
Topics: Acute Kidney Injury; Animals; Gentamicins; Ischemia; Kidney; Kidney Function Tests; Kidney Tubules, | 1990 |
Effects of FDP and Danshen on renal cortical Na-K-ATPase activity in rats after treatment with renal ischemia and gentamicin.
Topics: Animals; Drug Combinations; Drugs, Chinese Herbal; Fructose-Bisphosphatase; Gentamicins; Ischemia; K | 1989 |
The relative effects of aztreonam versus gentamicin on nephrotoxicity induced by warm ischemia in the presence and absence of cyclosporine.
Topics: Animals; Aztreonam; Cyclosporins; Gentamicins; Ischemia; Kidney; Male; Rats; Rats, Inbred Strains; R | 1989 |
Effects of enteral and intravenous antimicrobial treatment on survival following intestinal ischemia in rats.
Topics: Animals; Anti-Bacterial Agents; Bacteria, Anaerobic; Drug Therapy, Combination; Gentamicins; Gram-Ne | 1989 |
Acute ischemic retinopathy due to gentamicin injection.
Topics: Acute Disease; Gentamicins; Humans; Ischemia; Medication Errors; Necrosis; Retinal Diseases | 1986 |
Retinal toxicity secondary to intraocular gentamicin injection.
Topics: Adult; Aged; Aged, 80 and over; Eye; Fluorescein Angiography; Gentamicins; Humans; Injections; Ische | 1986 |
Healing of ischemic colonic anastomoses in the rat: role of antibiotic preparation.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Clindamycin; Colon; Erythromycin; Gentamicins; | 1985 |
[Brachial diplegia due to ischemia of the anterior horns during septicemia caused by Salmonella typhimurium].
Topics: Aged; Ampicillin; Anterior Horn Cells; Brain Diseases; Cerebral Ventricles; Electromyography; Female | 1974 |