gentamicin has been researched along with Injuries, Spinal Cord in 19 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In general, volume of distribution is significantly higher in the SCI population compared with the non-SCI population; however, clearance and half-life may be larger or no different." | 2.47 | Pharmacokinetics of aminoglycosides in patients with chronic spinal cord injury. ( Ensom, MH; Young, F, 2011) |
| "Population pharmacokinetic models for gentamicin were developed by using data obtained from 29 spinal cord-injured patients and 11 able-bodied control patients." | 1.29 | Comparison of population pharmacokinetic models for gentamicin in spinal cord-injured and able-bodied patients. ( Brunnemann, SR; Gilman, TM; Segal, JL, 1993) |
| " Pharmacokinetic parameters were derived using compartmental and model-independent analyses." | 1.27 | Gentamicin bioavailability and single-dose pharmacokinetics in spinal cord injury. ( Brunnemann, SR; Gray, DR; Segal, JL, 1988) |
| " The existence of these observed differences in pharmacokinetic parameters, however, emphasizes the need to define individual pharmacokinetic profiles and individualize dosing regimens in spinal man." | 1.27 | Gentamicin disposition kinetics in humans with spinal cord injury. ( Eltorai, IM; Gordon, SK; Gray, DR; Khonsari, F; Patel, J; Segal, JL, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (47.37) | 18.7374 |
| 1990's | 5 (26.32) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 1 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Ruijuan, Z | 1 |
| Li, X | 1 |
| Yingjie, W | 1 |
| Rui, W | 1 |
| Chunqing, L | 1 |
| Peerdeman, SM | 1 |
| de Groot, V | 1 |
| Feller, RE | 1 |
| Young, F | 1 |
| Ensom, MH | 1 |
| García-López, P | 1 |
| Martínez-Cruz, A | 1 |
| Guízar-Sahagún, G | 1 |
| Castañeda-Hernández, G | 1 |
| Shlaes, DM | 2 |
| Currie, CA | 2 |
| Rotter, G | 1 |
| Eanes, M | 1 |
| Floyd, R | 1 |
| Lin, SS | 1 |
| Vaccaro, AR | 1 |
| Reisch, S | 1 |
| Devine, M | 1 |
| Cotler, JM | 1 |
| Reich, SM | 1 |
| Montgomerie, JZ | 1 |
| John, JF | 1 |
| Atkins, LM | 1 |
| Gilmore, DS | 1 |
| Ashley, MA | 1 |
| Gilman, TM | 1 |
| Brunnemann, SR | 2 |
| Segal, JL | 3 |
| Vaidyanathan, S | 1 |
| Watt, JW | 1 |
| Singh, G | 1 |
| Soni, BM | 1 |
| Sett, P | 1 |
| Konya, H | 1 |
| Kuroda, J | 1 |
| Iwao, N | 1 |
| Morita, M | 1 |
| Wilson, TH | 1 |
| Rengachary, SS | 1 |
| Kugler, K | 1 |
| Watanabe, I | 1 |
| Hurley, JC | 1 |
| Louis, WJ | 1 |
| Tosolini, FA | 2 |
| Carlin, JB | 1 |
| Wise, KA | 1 |
| Kabalin, JN | 1 |
| Kessler, R | 1 |
| Gray, DR | 2 |
| Gordon, SK | 1 |
| Eltorai, IM | 1 |
| Khonsari, F | 1 |
| Patel, J | 1 |
| Saad, AF | 1 |
| Farrar, WE | 1 |
2 reviews available for gentamicin and Injuries, Spinal Cord
| Article | Year |
|---|---|
Pharmacokinetics of aminoglycosides in patients with chronic spinal cord injury.
Topics: Aminoglycosides; Anti-Bacterial Agents; Biological Availability; Chronic Disease; Cystatin C; Dose-R | 2011 |
Low-velocity gunshot wounds to the spine with an associated transperitoneal injury.
Topics: Adolescent; Adult; Antifungal Agents; Cefoxitin; Child; Colon; Discitis; Drug Therapy, Combination; | 1995 |
1 trial available for gentamicin and Injuries, Spinal Cord
| Article | Year |
|---|---|
Effects of Catheter Tracking Management on Urinary Tract Function and Infection Rates in Patients With Spinal Cord Injury.
Topics: Anti-Bacterial Agents; Catheters; Ciprofloxacin; Gentamicins; Humans; Levofloxacin; Piperacillin; Qu | 2023 |
16 other studies available for gentamicin and Injuries, Spinal Cord
| Article | Year |
|---|---|
In situ treatment of an infected intrathecal baclofen pump implant with gentamicin-impregnated collagen fleece.
Topics: Anti-Bacterial Agents; Baclofen; Collagen; Debridement; Drug Implants; Gentamicins; Humans; Infusion | 2010 |
Acute spinal cord injury changes the disposition of some, but not all drugs given intravenously.
Topics: Acute Disease; Analgesics, Non-Narcotic; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, N | 2007 |
Endemic gentamicin resistance R factors on a spinal cord injury unit.
Topics: Acinetobacter; Cross Infection; DNA Restriction Enzymes; DNA, Bacterial; Drug Resistance, Microbial; | 1983 |
Epidemiology of gentamicin-resistant, gram-negative bacillary colonization in a spinal cord injury unit.
Topics: Acinetobacter; Anti-Bacterial Agents; Cross Infection; Drug Resistance, Microbial; Enterobacteriacea | 1983 |
Increased frequency of large R-plasmids in Klebsiella pneumoniae colonizing patients with spinal cord injury.
Topics: Conjugation, Genetic; DNA Restriction Enzymes; Drug Resistance, Microbial; Gentamicins; Humans; Kleb | 1993 |
Comparison of population pharmacokinetic models for gentamicin in spinal cord-injured and able-bodied patients.
Topics: Adult; Gentamicins; Humans; Male; Middle Aged; Models, Biological; Population; Spinal Cord Injuries | 1993 |
Dosage of once-daily gentamicin in spinal cord injury patients.
Topics: Adult; Creatinine; Drug Administration Schedule; Drug Monitoring; Gentamicins; Humans; Kidney Functi | 2000 |
[Clinical experience with amikacin for chronic complicated urinary tract infections in myelopathogenic bladder. Clinical effect against gentamicin-resistant bacteria (author's transl)].
Topics: Adult; Aged; Amikacin; Chronic Disease; Drug Evaluation; Drug Resistance, Microbial; Gentamicins; Hu | 1978 |
Penetrating trauma of colon, cava, and cord.
Topics: Abdominal Injuries; Adult; Ampicillin; Chloramphenicol; Colon; Escherichia coli Infections; Gentamic | 1976 |
Intramedullary abscess following transpharyngeal stab injury.
Topics: Abscess; Adult; Autopsy; Brain Stem; Cephalothin; Cervical Vertebrae; Enterobacteriaceae Infections; | 1975 |
Antibiotic-induced release of endotoxin in chronically bacteriuric patients.
Topics: Anti-Bacterial Agents; Bacteriuria; Chronic Disease; Ciprofloxacin; Colony Count, Microbial; Endotox | 1991 |
Epidemiological surveillance of Acinetobacter species.
Topics: Acinetobacter Infections; Carrier State; Cross Infection; Drug Resistance, Microbial; Environmental | 1990 |
Infectious complications of penile prosthesis surgery.
Topics: Adult; Aged; Anti-Bacterial Agents; Cefazolin; Erectile Dysfunction; Gentamicins; Humans; Male; Midd | 1988 |
Gentamicin bioavailability and single-dose pharmacokinetics in spinal cord injury.
Topics: Adult; Biological Availability; Gentamicins; Humans; Injections, Intramuscular; Male; Middle Aged; M | 1988 |
Gentamicin disposition kinetics in humans with spinal cord injury.
Topics: Adult; Gentamicins; Humans; Kinetics; Male; Middle Aged; Paralysis; Paraplegia; Spinal Cord Injuries | 1985 |
Intracisternal and intrathecal injections of gentamicin in enterobacter meningitis.
Topics: Adult; Cisterna Magna; Enterobacteriaceae Infections; Gentamicins; Humans; Injections; Injections, I | 1974 |