gentamicin has been researched along with Injuries, Multiple in 8 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Over a 6-yr period, 360 multiple trauma patients (case patients) submitted to SDD were compared with 360 patients not receiving SDD (controls)." | 1.32 | Long-term (6-year) effect of selective digestive decontamination on antimicrobial resistance in intensive care, multiple-trauma patients. ( Albanese, J; Antonini, F; Leone, M; Martin, C; Nguyen-Michel, A, 2003) |
| " However, the pharmacokinetic parameters are variable in these patients." | 1.31 | Population pharmacokinetics of aminoglycosides in critically ill trauma patients on once-daily regimens. ( Barletta, JF; Erstad, BL; Johnson, SB; Nix, DE; Nix, LC, 2000) |
| " Although adequate maintenance dosing requires individualization based on pharmacokinetic analyses, large aminoglycoside doses can be used safely in patients with blunt trauma if appropriate monitoring is employed." | 1.28 | Aminoglycoside pharmacokinetics: dosage requirements and nephrotoxicity in trauma patients. ( Fink, MP; Murphy, SG; Stein, KL; Townsend, PL, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 5 (62.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Leone, M | 1 |
| Albanese, J | 2 |
| Antonini, F | 1 |
| Nguyen-Michel, A | 1 |
| Martin, C | 2 |
| Lin, SS | 1 |
| Vaccaro, AR | 1 |
| Reisch, S | 1 |
| Devine, M | 1 |
| Cotler, JM | 1 |
| Reich, SM | 1 |
| Liu, G | 1 |
| Du, J | 1 |
| Quinio, B | 1 |
| Bues-Charbit, M | 1 |
| Viviand, X | 1 |
| Tandon, SC | 1 |
| Thomas, PB | 1 |
| Barletta, JF | 1 |
| Johnson, SB | 1 |
| Nix, DE | 1 |
| Nix, LC | 1 |
| Erstad, BL | 1 |
| Ankin, LN | 1 |
| Polishchuk, NE | 1 |
| Ankin, NL | 1 |
| Townsend, PL | 1 |
| Fink, MP | 1 |
| Stein, KL | 1 |
| Murphy, SG | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized,Double-Blind,Placebo-Controled Trial of Selective Digestive Decontamination Using Oral Gentamicin and Oral Polymyxin E for Eradication of Carbapenem-Resistant Klebsiella Pneumoniae Carriage[NCT00753558] | 0 participants | Interventional | 2008-11-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for gentamicin and Injuries, Multiple
| Article | Year |
|---|---|
Low-velocity gunshot wounds to the spine with an associated transperitoneal injury.
Topics: Adolescent; Adult; Antifungal Agents; Cefoxitin; Child; Colon; Discitis; Drug Therapy, Combination; | 1995 |
1 trial available for gentamicin and Injuries, Multiple
| Article | Year |
|---|---|
Selective decontamination of the digestive tract in multiple trauma patients. A prospective double-blind, randomized, placebo-controlled study.
Topics: Amphotericin B; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antifungal Agents; Bronchopneumonia; | 1996 |
6 other studies available for gentamicin and Injuries, Multiple
| Article | Year |
|---|---|
Long-term (6-year) effect of selective digestive decontamination on antimicrobial resistance in intensive care, multiple-trauma patients.
Topics: Administration, Cutaneous; Administration, Oral; Adult; Amphotericin B; Anti-Bacterial Agents; Antib | 2003 |
Irrigation and traction therapy for open fracture with large-sized full-thickness skin-deficit and severely infected wound.
Topics: Adolescent; Adult; Child; Female; Fractures, Open; Gentamicins; Humans; Male; Middle Aged; Multiple | 1995 |
Persistent osteomyelitis of the femur--2 cases of exchange intramedullary nailing with gentamicin beads in the nail.
Topics: Adult; Anti-Bacterial Agents; Arthrodesis; Femoral Fractures; Fracture Fixation, Intramedullary; Fra | 1996 |
Population pharmacokinetics of aminoglycosides in critically ill trauma patients on once-daily regimens.
Topics: Adolescent; Adult; Age Factors; Aged; Anti-Bacterial Agents; Body Weight; Creatinine; Critical Illne | 2000 |
[Osteosynthesis in patients with associated cranio-cerebral trauma].
Topics: Arm Injuries; Brain Concussion; Craniocerebral Trauma; External Fixators; Fracture Fixation; Fractur | 1991 |
Aminoglycoside pharmacokinetics: dosage requirements and nephrotoxicity in trauma patients.
Topics: Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Craniocerebral Trauma; Creatinine; | 1989 |