Page last updated: 2024-10-27

gentamicin and Inflammation

gentamicin has been researched along with Inflammation in 71 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
"1% indomethacin and gentamicin proved to be effective and well tolerated in preventing inflammation after cataract surgery."9.08[Efficacy and tolerability of a combination of indomethacin and gentamicin for preventing inflammation after cataract surgery]. ( Adenis, JP; Allaire, C; Brasseur, G; Couderc, JL; Dascotte, JC; Hoang-Xuan, T; Renard, G; Rouland, JF; Trinquand, C; Ullern, M, 1996)
"Diclofenac appears to be as effective as betamethasone in controlling postoperative inflammation following strabismus surgery and may offer a safer alternative to the use of topical steroids."9.08Comparison of the efficacy of diclofenac and betamethasone following strabismus surgery. ( Butt, Z; Fleck, B; McIlwaine, G; Wright, M, 1997)
" This study was aimed at evaluating the effect of rutin on oxidative stress, inflammation, apoptosis, and autophagy in gentamicin-induced nephrotoxicity in rats."7.81Rutin attenuates gentamicin-induced renal damage by reducing oxidative stress, inflammation, apoptosis, and autophagy in rats. ( Aktas, E; Benzer, F; Hanedan, B; Kandemir, FM; Kilic, K; Kirbas, A; Ozkaraca, M; Yildirim, BA, 2015)
"Gentamicin may cause acute kidney injury."7.81Rapamycin protects against gentamicin-induced acute kidney injury via autophagy in mini-pig models. ( Bai, XY; Cai, G; Chen, X; Cui, J; Ding, R; Hong, Q; Sun, X, 2015)
"The present study aimed to investigate whether macrophage-stimulating protein (MSP) treatment attenuates renal apoptosis and inflammation in gentamicin (GM)-induced tubule injury and its underlying molecular mechanisms."7.79Macrophage-stimulating protein attenuates gentamicin-induced inflammation and apoptosis in human renal proximal tubular epithelial cells. ( Bae, EH; Choi, JS; Kim, CS; Kim, EY; Kim, KK; Kim, SW; Lee, JU; Lee, KE; Ma, SK, 2013)
"Gentamicin is an important broad-spectrum antibiotic; nevertheless, it exhibits serious nephrotoxic adverse effects."5.62HPLC-ESI/MS profiling, phytoconstituent isolation and evaluation of renal function, oxidative stress and inflammation in gentamicin-induced nephrotoxicity in rats of Ficus spragueana Mildbr. & Burret. ( Aboutabl, ME; Masoud, MA; Nassar, MI; Raslan, MA; Taher, RF, 2021)
"Gentamicin is an aminoglycoside antibiotic commonly administrated to patients with Gram-negative infections."5.56Toll-like receptor-2 mediates systemic inflammation in gentamicin-induced rat nephrotoxicity. ( Janfeshan, S; Karimi, Z; Pakfetrat, Z; Roozbeh, J, 2020)
"MS extract can protect the kidney against toxic effects of gentamicin, and thus, the degree of harmful effects of nephrotoxicity on remote organs including the liver will be decreased."5.51Amelioration of renal and hepatic function, oxidative stress, inflammation and histopathologic damages by Malva sylvestris extract in gentamicin induced renal toxicity. ( Jassemi, SV; Madani, SH; Modarresi, M; Mohamadi Yarijani, Z; Najafi, H; Shackebaei, D, 2019)
"Gentamicin was administered intraperitoneally at a dosage of 100 mg/kg body weight, once daily for 6 days."5.35Diallyl sulfide enhances antioxidants and inhibits inflammation through the activation of Nrf2 against gentamicin-induced nephrotoxicity in Wistar rats. ( Arumugam, M; Kalayarasan, S; Manikandan, R; Prabhu, PN; Sriram, N; Sudhandiran, G, 2009)
"1% indomethacin and gentamicin proved to be effective and well tolerated in preventing inflammation after cataract surgery."5.08[Efficacy and tolerability of a combination of indomethacin and gentamicin for preventing inflammation after cataract surgery]. ( Adenis, JP; Allaire, C; Brasseur, G; Couderc, JL; Dascotte, JC; Hoang-Xuan, T; Renard, G; Rouland, JF; Trinquand, C; Ullern, M, 1996)
"Diclofenac appears to be as effective as betamethasone in controlling postoperative inflammation following strabismus surgery and may offer a safer alternative to the use of topical steroids."5.08Comparison of the efficacy of diclofenac and betamethasone following strabismus surgery. ( Butt, Z; Fleck, B; McIlwaine, G; Wright, M, 1997)
"Renal failure caused by gentamicin is mainly mediated through oxidative damage, inflammation, and apoptosis."4.31Comparison of the effect of vitamin C and selenium nanoparticles on gentamicin-induced renal impairment in male rats: a biochemical, molecular and histological study. ( Akbari, A; Hameed Sultan, A; Kareem, LA; Kurtas, PT; Zheng, S, 2023)
" Moreover, acute pneumonia obtained by BhvKp with intranasal method, was characterized in terms of histopathology of pulmonary lesions, biomarkers of inflammation level, leukocytes cells infiltration extent in mice, and was assessed treatment of them with PSKP16 multiplicity of infection (MOI: 10), either individually or in combination with gentamicin."4.31Characterization of novel bacteriophage PSKP16 and its therapeutic potential against β-lactamase and biofilm producer strain of K2-Hypervirulent Klebsiella pneumoniae pneumonia infection in mice model. ( Bakht, M; Foroughi, F; Javadi, A; Marashi, SMA; Nikkhahi, F; Rahimi, S, 2023)
" Necrosis, apoptosis and inflammation are commonly considered as the leading mechanism in acute kidney injury (AKI) induced by gentamicin (GEN), which is a useful antibiotic for treating the infection of Gram-negative bacterial."4.12Protective effect of inhibiting necroptosis on gentamicin-induced nephrotoxicity. ( Chen, SQ; Feng, XW; Gong, Q; Hu, BF; Li, C; Li, J; Liu, MM; Ma, WX; Meng, XM; Wang, F; Wang, JN; Wang, XF; Wen, JG; Yue, L, 2022)
"In the last 4 years the authors observed a trend that correcting vitamin D deficiency in newly diagnosed cases of Meniere's disease decreased the necessity of the ablative therapy with intratympanic gentamicin."3.88Vitamin D supplementation may improve symptoms in Meniere's disease. ( Büki, B; Jünger, H; Lundberg, YW, 2018)
"Gentamicin may cause acute kidney injury."3.81Rapamycin protects against gentamicin-induced acute kidney injury via autophagy in mini-pig models. ( Bai, XY; Cai, G; Chen, X; Cui, J; Ding, R; Hong, Q; Sun, X, 2015)
" This study was aimed at evaluating the effect of rutin on oxidative stress, inflammation, apoptosis, and autophagy in gentamicin-induced nephrotoxicity in rats."3.81Rutin attenuates gentamicin-induced renal damage by reducing oxidative stress, inflammation, apoptosis, and autophagy in rats. ( Aktas, E; Benzer, F; Hanedan, B; Kandemir, FM; Kilic, K; Kirbas, A; Ozkaraca, M; Yildirim, BA, 2015)
"The present study aimed to investigate whether macrophage-stimulating protein (MSP) treatment attenuates renal apoptosis and inflammation in gentamicin (GM)-induced tubule injury and its underlying molecular mechanisms."3.79Macrophage-stimulating protein attenuates gentamicin-induced inflammation and apoptosis in human renal proximal tubular epithelial cells. ( Bae, EH; Choi, JS; Kim, CS; Kim, EY; Kim, KK; Kim, SW; Lee, JU; Lee, KE; Ma, SK, 2013)
"Gentamicin nephrotoxicity is one of the most common causes of acute kidney injury (AKI)."3.78Hypoxia-inducible factor activation protects the kidney from gentamicin-induced acute injury. ( Ahn, JM; Ahn, SY; Chae, DW; Chin, HJ; Kim, S; Lee, YM; Na, KY; Oh, SW; You, SJ, 2012)
" The aim of this study was to determine effects of inhibiting hydrogen sulphide biosynthesis by DL-propargyl glycine (an irreversible inhibitor of cystathionine gamma-lyase) on inflammation, necrosis and renal function, following treatment with gentamicin in rats."3.78Inhibition of cystathionine gamma-lyase and the biosynthesis of endogenous hydrogen sulphide ameliorates gentamicin-induced nephrotoxicity. ( Dam, VP; Kinobe, RT; Ross, A; Scott, JL, 2012)
"Sutural materials containing antibiotics such as gentamicin and tetracycline were studied on dogs with respect to the action on development of inflammation reactions after operations on the large intestine."3.68[Prevention of postoperative infectious complications with suture materials containing gentamicin]. ( Iskanderov, FI; Iushkov, SF; Klimenkov, AA; Petrova, EA; Petrovichev, NN; Smolianskaia, AZ, 1991)
"Ligenten gel is a combined dosage form containing gentamicin (a broad spectrum antibiotic), lidocaine (an anesthetic) and ethonium (an antiseptic)."2.67[Ligenten--a combination drug with anesthetic and antibacterial action for local use in urology and gynecology]. ( Darenkov, AF; Kotliarova, GA; Lebed', SV; Makarov, OV; Perepanova, TS; Savchenko, TN; Strachunskiĭ, LS; Tsibina, LV; Vasil'ev, MM; Zharov, EV, 1994)
"Gentamicin was shown to be highly active as compared to kanamycin and other antibiotics against the main causative agents of purulent inflammatory infections including multiresistant E."2.64[Effectiveness of gentamicin sulfate in suppurative-inflammatory processes of varying localization]. ( Bogomolova, NS; Kozlov, VA; Rodoman, VE; Saksen, EF; Sorokina, MI, 1977)
"Daidzein activity was associated with an increase in antioxidant biomarkers such as superoxide dismutase (SOD) and glutathione reductase (GSH), whereas lipid peroxidation (LPO) and nitric oxide (NO) production were decreased in a dose-dependent factor."1.72Daidzein normalized gentamicin-induced nephrotoxicity and associated pro-inflammatory cytokines in MDCK and zebrafish: Possible mechanism of nephroprotection. ( Arockiaraj, J; Guru, A; Juliet, A; Mothana, RA; Murugan, R; Noman, OM; Pachaiappan, R; Sudhakaran, G; Velayutham, M, 2022)
"Gentamicin is an important broad-spectrum antibiotic; nevertheless, it exhibits serious nephrotoxic adverse effects."1.62HPLC-ESI/MS profiling, phytoconstituent isolation and evaluation of renal function, oxidative stress and inflammation in gentamicin-induced nephrotoxicity in rats of Ficus spragueana Mildbr. & Burret. ( Aboutabl, ME; Masoud, MA; Nassar, MI; Raslan, MA; Taher, RF, 2021)
"Daphnetin (Daph) is a natural coumarin derivative that is clinically used to treat rheumatoid arthritis and coagulopathy and exhibits antioxidant effects."1.62Daphnetin ameliorated GM-induced renal injury through the suppression of oxidative stress and apoptosis in mice. ( Ci, X; Fan, C; Fan, X; Gao, Y; Gu, W; Ma, N, 2021)
"Gentamicin is an aminoglycoside antibiotic commonly administrated to patients with Gram-negative infections."1.56Toll-like receptor-2 mediates systemic inflammation in gentamicin-induced rat nephrotoxicity. ( Janfeshan, S; Karimi, Z; Pakfetrat, Z; Roozbeh, J, 2020)
"Infective endocarditis is associated with significant morbidity and mortality, despite advances in diagnosis and treatment strategies."1.51No Fever, No Murmur, No Problem? A Concealed Case of Infective Endocarditis. ( Gorman, M; McCann, M; McKeown, B, 2019)
"MS extract can protect the kidney against toxic effects of gentamicin, and thus, the degree of harmful effects of nephrotoxicity on remote organs including the liver will be decreased."1.51Amelioration of renal and hepatic function, oxidative stress, inflammation and histopathologic damages by Malva sylvestris extract in gentamicin induced renal toxicity. ( Jassemi, SV; Madani, SH; Modarresi, M; Mohamadi Yarijani, Z; Najafi, H; Shackebaei, D, 2019)
"Gentamicin treatment decreased fall latency of mice and gentamicin treatment together with alpha-linolenic acid increased fall latency of mice."1.46Protective effect of alpha-linolenic acid on gentamicin-induced ototoxicity in mice. ( Doran, F; Erdoğan, KE; Kaplan, HM; Şingirik, E, 2017)
"Gentamicin was present in lamellar tissue at much higher concentrations than peripheral serum."1.36Development of intraosseous infusion of the distal phalanx to access the foot lamellar circulation in the standing, conscious horse. ( Mills, PC; Nourian, AR; Pollitt, CC, 2010)
"Gentamicin was administered intraperitoneally at a dosage of 100 mg/kg body weight, once daily for 6 days."1.35Diallyl sulfide enhances antioxidants and inhibits inflammation through the activation of Nrf2 against gentamicin-induced nephrotoxicity in Wistar rats. ( Arumugam, M; Kalayarasan, S; Manikandan, R; Prabhu, PN; Sriram, N; Sudhandiran, G, 2009)
"Gentamicin was given intravenously (10 mg/kg) and CSF and blood samples were taken."1.26Determination of cerebrospinal fluid gentamicin in the beagle using an indwelling cerebral ventricular cannula. ( Coppoc, GL; Riviere, JE, 1981)
"No gentamicin was detected in ventricular CSF of four patients at a time when gentamicin was being administered only intravenously."1.26Intraventricular and parenteral gentamicin therapy for ventriculitis in children. ( Blevins, J; Ericsson, CD; Miner, ME; Pickering, LK; Ruiz-Palacios, G, 1978)

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-199017 (23.94)18.7374
1990's10 (14.08)18.2507
2000's5 (7.04)29.6817
2010's25 (35.21)24.3611
2020's14 (19.72)2.80

Authors

AuthorsStudies
Guru, A1
Sudhakaran, G1
Velayutham, M1
Murugan, R1
Pachaiappan, R1
Mothana, RA1
Noman, OM1
Juliet, A1
Arockiaraj, J1
Hu, BF1
Gong, Q1
Chen, SQ1
Yue, L1
Ma, WX1
Wang, F1
Feng, XW1
Wang, JN1
Li, C2
Liu, MM1
Wang, XF1
Meng, XM1
Li, J2
Wen, JG1
Li, Y1
Ding, Q1
Gao, J1
Hou, P1
Xu, J1
Cao, K1
Hu, M1
Cheng, L1
Wang, X1
Yang, X1
Zheng, S1
Hameed Sultan, A1
Kurtas, PT1
Kareem, LA1
Akbari, A1
Xu, XJ1
Zhang, ML1
Hou, YM1
Zhang, K1
Yao, DH1
Li, GY1
Kou, WB1
Wang, HY1
Wang, JH1
Metin, TO2
Bayrak, G2
Yaman, S2
Doganer, A2
Yoldas, A2
Eser, N2
Aykan, DA2
Yilmaz, BC2
Kurt, AH2
Ayaz, L2
Sahin, M2
Cao, B1
Wang, C2
Guo, P1
Zhang, Q1
Sun, H1
Wen, H1
Chen, X2
Wang, Y2
Huang, S1
Xue, W1
Rahimi, S1
Bakht, M1
Javadi, A1
Foroughi, F1
Marashi, SMA1
Nikkhahi, F1
Karimi, Z1
Pakfetrat, Z1
Roozbeh, J1
Janfeshan, S1
Silva de Almeida, TC1
Lanza, K1
da Silva Filha, R1
C Campos, LMC1
Fonseca, EG1
Chagas, MW1
Rocha, NP1
de Sá, MA1
Vieira, MAR1
Caliari, MV1
Kangussu, LM1
Ferreira, AJ1
Simões E Silva, AC1
Sharma, VC1
Kaushik, A1
Dey, YN1
Srivastava, B1
Wanjari, M1
Pawar, S1
Chougule, S1
Sun, Y1
He, Z1
Gong, S1
Yuan, S1
Li, T1
Ning, N1
Xing, L1
Zhang, L1
Chen, F1
Li, Z1
Wang, J1
Luo, D1
Wang, H1
Fan, X1
Gu, W1
Gao, Y1
Ma, N1
Fan, C1
Ci, X1
Taher, RF1
Raslan, MA1
Masoud, MA1
Nassar, MI1
Aboutabl, ME1
Arjinajarn, P1
Chueakula, N1
Pongchaidecha, A1
Jaikumkao, K1
Chatsudthipong, V1
Mahatheeranont, S1
Norkaew, O1
Chattipakorn, N1
Lungkaphin, A1
Olekson, MA1
Rose, LF1
Carlsson, AH1
Fletcher, JL1
Leung, KP1
Chan, RK1
Kaplan, HM1
Şingirik, E1
Erdoğan, KE1
Doran, F1
El Amir, AM1
Tanious, DG1
Mansour, HA1
Valguarnera, E1
Spera, JM1
Czibener, C1
Fulgenzi, FR1
Casabuono, AC1
Altabe, SG1
Pasquevich, KA1
Guaimas, F1
Cassataro, J1
Couto, AS1
Ugalde, JE1
Büki, B1
Jünger, H1
Lundberg, YW1
Ahmed, HI1
Mohamed, EA1
Mohamadi Yarijani, Z1
Najafi, H1
Shackebaei, D1
Madani, SH1
Modarresi, M1
Jassemi, SV1
McCann, M1
Gorman, M1
McKeown, B1
Jiang, M1
Li, H1
Johnson, A1
Karasawa, T1
Zhang, Y1
Meier, WB1
Taghizadeh, F1
Kachelmeier, A1
Steyger, PS1
Lee, KE1
Kim, EY1
Kim, CS1
Choi, JS1
Bae, EH1
Ma, SK1
Kim, KK1
Lee, JU1
Kim, SW1
Pankhurst, T1
Mani, D1
Ray, D1
Jham, S1
Borrows, R1
Coleman, JJ1
Rosser, D1
Ball, S1
Woo, JI1
Oh, S1
Webster, P1
Lee, YJ1
Lim, DJ1
Moon, SK1
Patel, K1
Lamb, B1
Pathak, S1
Peters, J1
El Gamal, AA1
AlSaid, MS1
Raish, M2
Al-Sohaibani, M1
Al-Massarani, SM1
Ahmad, A2
Hefnawy, M1
Al-Yahya, M1
Basoudan, OA1
Rafatullah, S1
Kandemir, FM1
Ozkaraca, M1
Yildirim, BA1
Hanedan, B1
Kirbas, A1
Kilic, K1
Aktas, E1
Benzer, F1
Cui, J1
Bai, XY1
Sun, X1
Cai, G1
Hong, Q1
Ding, R1
Hussain, A1
Curry, B1
Cahalan, L1
Minkin, S1
Gartner, M1
Cahalan, P1
Ansari, MA1
Ahmad, SF1
Mudassar, S1
Mohsin, K1
Shakeel, F1
Korashy, HM1
Bakheet, SA1
Jose, SP1
S, A1
Im, K1
M, R1
Santhosh, S1
S, S1
B, GK1
C, P1
Nourian, AR2
Mills, PC2
Pollitt, CC2
Kalayarasan, S1
Prabhu, PN1
Sriram, N1
Manikandan, R1
Arumugam, M1
Sudhandiran, G1
Venditto, M1
du Montcel, ST1
Robert, J1
Trystam, D1
Dighiero, J1
Hue, D1
Bessette, C1
Deray, G1
Mercadal, L1
Dam, VP1
Scott, JL1
Ross, A1
Kinobe, RT1
Ahn, JM1
You, SJ1
Lee, YM1
Oh, SW1
Ahn, SY1
Kim, S1
Chin, HJ1
Chae, DW1
Na, KY1
Lozano, FS1
García-Criado, FJ1
Fresnadillo, MJ1
García, E1
García, JE1
Gómez-Alonso, A1
Shliapnikov, SA1
Karpov, OI1
Oranskiĭ, IF1
Zaĭtsev, AA1
Burugapalli, K1
Koul, V1
Dinda, AK1
Eljarrat-Binstock, E1
Raiskup, F1
Frucht-Pery, J1
Domb, AJ1
Ustinova, EI1
Khil'ko, ON1
Riviere, JE1
Coppoc, GL1
Anderson, JM1
Niven, H1
Pelagalli, J1
Olanoff, LS1
Jones, RD1
Darenkov, AF1
Perepanova, TS1
Kotliarova, GA1
Strachunskiĭ, LS1
Tsibina, LV1
Zharov, EV1
Lebed', SV1
Makarov, OV1
Savchenko, TN1
Vasil'ev, MM1
Suharwardy, J1
Ling, C1
Bell, JA1
Munton, CG1
Friedland, IR1
Jafari, H1
Ehrett, S1
Rinderknecht, S1
Paris, M1
Coulthard, M1
Saxen, H1
Olsen, K1
McCracken, GH1
Kisina, VI1
Men'shikov, DD1
Vasina, TA1
Volenko, AV1
Zalogueva, GV1
Vasil'ev, VA1
Renard, G1
Adenis, JP1
Rouland, JF1
Dascotte, JC1
Brasseur, G1
Couderc, JL1
Hoang-Xuan, T1
Ullern, M1
Allaire, C1
Trinquand, C1
Wright, M1
Butt, Z1
McIlwaine, G1
Fleck, B1
Bashtan, VP1
Bogomolova, NS1
Rodoman, VE1
Kozlov, VA1
Saksen, EF1
Sorokina, MI1
Pozdniakova, VP1
Petrova, MA1
Marshak, AM1
Makarenkova, RV1
Zamotaev, IP1
Pickering, LK1
Ericsson, CD1
Ruiz-Palacios, G1
Blevins, J1
Miner, ME1
Drapkin, AJ1
Michel, J1
Sacks, T1
Beller, AJ1
Lysikiewicz, A1
Sliwiński, W1
Forster, RK1
Zachary, IG1
Cottingham, AJ1
Norton, EW1
Solheim, E1
Pinholt, EM1
Bang, G1
Sudmann, E1
Iushkov, SF1
Klimenkov, AA1
Iskanderov, FI1
Smolianskaia, AZ1
Petrovichev, NN1
Petrova, EA1
Ladodo, OB1
Yannis, RA1
Rissing, JP1
Buxton, TB1
Shockley, RK1
Graham, RO1
Peyman, GA1
Paparella, MM1
Apfelberg, DB1
Waisbren, BA1
Masters, FW1
Robinson, DW1
Graybill, JR1
Pierson, DN1
Charache, P1
van der Waarde, K1
van de Wiel-Korstanje, M1
Golden, B1
Coppel, SP1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effectiveness of BoneSeal® on Bone Hemostats in Patients Undergoing Cardiothoracic Surgery[NCT03085017]57 participants (Actual)Interventional2017-06-07Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Ease of Use

Qualitative determination of product application and hemostatic qualities graded by the surgeon using a scale from 1-5 with 1 being very easy and 5 being very difficult (NCT03085017)
Timeframe: The time frame for assessing the ease of product application is the short interval a the conclusion of the operation when we are applying the topical hemostatic agent to the sternal bone marrow. In other words at the end of the case, this takes <10 min.

Interventionunits on a scale (Median)
Ostene4
BoneSeal1

End of Surgery Bleeding

Qualitative determination of of the amount of bleeding at the sternum at the end of surgery by the surgeon using a scale from 1-5 with 1 none and 5 being perfuse (NCT03085017)
Timeframe: End of surgery (closure of the chest)

Interventionunits on a scale (Median)
Ostene4
BoneSeal2

Intra-operative Blood Units

Units of blood/blood products transfused during surgery (NCT03085017)
Timeframe: 0-3 hours

InterventionBlood Units (Mean)
Ostene0.50
BoneSeal0.26

Number of Participants Experiencing Re-bleed

Occurrence of re-bleeding during the operation will be noted. Reapplication of product will not occur. (NCT03085017)
Timeframe: 0-3 hours

InterventionParticipants (Count of Participants)
Ostene25
BoneSeal3

Number of Participants Requiring Use of Another Product During Surgery

The surgeon's determination and need for the use of another product (FloSeal) during surgery to stop bleeding or re-bleed at the sternum. (NCT03085017)
Timeframe: During surgery, up to 3 hours

InterventionParticipants (Count of Participants)
Ostene13
BoneSeal1

Number of Participants With Infection

The presence of an infection at the sternum at any time up to 30 days post surgery. (NCT03085017)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Ostene1
BoneSeal0

Number of Participants With Post Operative Complications Related to the Device

Sternal wound infection or other complications related to the device or its use within 30 days post procedure (NCT03085017)
Timeframe: 30 days

InterventionParticipants (Count of Participants)
Ostene2
BoneSeal0

Post-operative Blood Units

Units of blood/blood products transfused within 24 hours post surgery (NCT03085017)
Timeframe: 3-24 hours

InterventionBlood Units (Mean)
Ostene0.50
BoneSeal0.26

Hemoglobin

Postoperative hemoglobin as compared to baseline preoperative readings (NCT03085017)
Timeframe: Pre-operative (baseline) and Post-operative (3-6 hours after baseline)

,
Interventiong/dL (Mean)
Pre-operative HemoglobinPost-operative hemoglobin
BoneSeal12.710.9
Ostene12.79.9

Surgical Site Drainage

Post-operative chest tube output (NCT03085017)
Timeframe: 6, 12, 18 and 24 hours

,
InterventionmL (Mean)
6 Hour12 Hour18 Hour24 Hour
BoneSeal294.3439.3568.3647.1
Ostene309.3463.7598.4683.5

Reviews

1 review available for gentamicin and Inflammation

ArticleYear
Development of an intra-lamellar microdialysis method for laminitis investigations in horses.
    Veterinary journal (London, England : 1997), 2010, Volume: 183, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Area Under Curve; Enzyme-Linked Immunosorbent Assay; Extracellular S

2010

Trials

9 trials available for gentamicin and Inflammation

ArticleYear
[Comparative clinical-economic analysis of antibiotic therapy in pyogenic inflammatory diseases of the lower extremities].
    Vestnik khirurgii imeni I. I. Grekova, 2003, Volume: 162, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cefazolin; Cost-Benefit Analysis; Female;

2003
[Ligenten--a combination drug with anesthetic and antibacterial action for local use in urology and gynecology].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1994, Volume: 39, Issue:8

    Topics: Adult; Anesthetics, Local; Anti-Infective Agents; Anti-Infective Agents, Local; Child; Drug Combinat

1994
A comparative trial between diclofenac-gentamicin and betamethasone-neomycin drops in patients undergoing cataract extraction.
    Eye (London, England), 1994, Volume: 8 ( Pt 5)

    Topics: Aged; Aged, 80 and over; Betamethasone; Cataract Extraction; Diclofenac; Female; Gentamicins; Humans

1994
[The combined preparation ligentin in the treatment of inflammatory disease of the urogenital organs].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1995, Volume: 40, Issue:7

    Topics: Adult; Anesthetics, Local; Anti-Infective Agents; Drug Combinations; Female; Female Urogenital Disea

1995
[Efficacy and tolerability of a combination of indomethacin and gentamicin for preventing inflammation after cataract surgery].
    Journal francais d'ophtalmologie, 1996, Volume: 19, Issue:11

    Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroida

1996
Comparison of the efficacy of diclofenac and betamethasone following strabismus surgery.
    The British journal of ophthalmology, 1997, Volume: 81, Issue:4

    Topics: Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Betamethasone; Child; Child, Prescho

1997
[Clinical effectiveness of the use of liposomes with antibiotics and ecterocide in purulent-inflammatory thoracic and abdominal complications].
    Klinichna khirurhiia, 1997, Issue:1

    Topics: Adolescent; Adult; Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents, Local; Digestive System

1997
[Effectiveness of gentamicin sulfate in suppurative-inflammatory processes of varying localization].
    Antibiotiki, 1977, Volume: 22, Issue:6

    Topics: Biopharmaceutics; Clinical Trials as Topic; Drug Evaluation; Drug Resistance, Microbial; Gentamicins

1977
[Clinical effectiveness of carbenicillin in suppurative inflammatory processes of varying localization].
    Antibiotiki, 1979, Volume: 24, Issue:7

    Topics: Adult; Ampicillin; Carbenicillin; Clinical Trials as Topic; Drug Evaluation; Drug Therapy, Combinati

1979

Other Studies

61 other studies available for gentamicin and Inflammation

ArticleYear
Daidzein normalized gentamicin-induced nephrotoxicity and associated pro-inflammatory cytokines in MDCK and zebrafish: Possible mechanism of nephroprotection.
    Comparative biochemistry and physiology. Toxicology & pharmacology : CBP, 2022, Volume: 258

    Topics: Animals; Antioxidants; Cytokines; Dogs; Gentamicins; Inflammation; Isoflavones; Kidney; Nitric Oxide

2022
Protective effect of inhibiting necroptosis on gentamicin-induced nephrotoxicity.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2022, Volume: 36, Issue:9

    Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Apoptosis; Gentamicins; Inflammation; Necroptos

2022
Novel mechanisms underlying inhibition of inflammation-induced angiogenesis by dexamethasone and gentamicin via PI3K/AKT/NF-κB/VEGF pathways in acute radiation proctitis.
    Scientific reports, 2022, 08-18, Volume: 12, Issue:1

    Topics: Animals; Dexamethasone; Gastritis; Gentamicins; Inflammation; Mice; Mice, Inbred C57BL; Neovasculari

2022
Comparison of the effect of vitamin C and selenium nanoparticles on gentamicin-induced renal impairment in male rats: a biochemical, molecular and histological study.
    Toxicology mechanisms and methods, 2023, Volume: 33, Issue:4

    Topics: Animals; Antioxidants; Ascorbic Acid; Gentamicins; Inflammation; Kidney; Male; Oxidative Stress; Rat

2023
The
    Molecules (Basel, Switzerland), 2022, Oct-21, Volume: 27, Issue:20

    Topics: Acute Kidney Injury; Amomum; Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; bcl-2-Assoc

2022
Expression of ER stress markers (GRP78 and PERK) in experimental nephrotoxicity induced by cisplatin and gentamicin: roles of inflammatory response and oxidative stress.
    Naunyn-Schmiedeberg's archives of pharmacology, 2023, Volume: 396, Issue:4

    Topics: Animals; Cisplatin; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulu

2023
Expression of ER stress markers (GRP78 and PERK) in experimental nephrotoxicity induced by cisplatin and gentamicin: roles of inflammatory response and oxidative stress.
    Naunyn-Schmiedeberg's archives of pharmacology, 2023, Volume: 396, Issue:4

    Topics: Animals; Cisplatin; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulu

2023
Expression of ER stress markers (GRP78 and PERK) in experimental nephrotoxicity induced by cisplatin and gentamicin: roles of inflammatory response and oxidative stress.
    Naunyn-Schmiedeberg's archives of pharmacology, 2023, Volume: 396, Issue:4

    Topics: Animals; Cisplatin; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulu

2023
Expression of ER stress markers (GRP78 and PERK) in experimental nephrotoxicity induced by cisplatin and gentamicin: roles of inflammatory response and oxidative stress.
    Naunyn-Schmiedeberg's archives of pharmacology, 2023, Volume: 396, Issue:4

    Topics: Animals; Cisplatin; Endoplasmic Reticulum; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulu

2023
Photo-crosslinked enhanced double-network hydrogels based on modified gelatin and oxidized sodium alginate for diabetic wound healing.
    International journal of biological macromolecules, 2023, Aug-01, Volume: 245

    Topics: Alginates; Anti-Bacterial Agents; Diabetes Mellitus; Gelatin; Gentamicins; Humans; Hydrogels; Inflam

2023
Characterization of novel bacteriophage PSKP16 and its therapeutic potential against β-lactamase and biofilm producer strain of K2-Hypervirulent Klebsiella pneumoniae pneumonia infection in mice model.
    BMC microbiology, 2023, 08-23, Volume: 23, Issue:1

    Topics: Animals; Bacteriophages; Biofilms; Disease Models, Animal; Gentamicins; Inflammation; Klebsiella pne

2023
Toll-like receptor-2 mediates systemic inflammation in gentamicin-induced rat nephrotoxicity.
    Clinical and experimental pharmacology & physiology, 2020, Volume: 47, Issue:9

    Topics: Animals; Cytokines; Disease Models, Animal; Gentamicins; Inflammation; Inflammation Mediators; Kidne

2020
ACE2 activator diminazene aceturate exerts renoprotective effects in gentamicin-induced acute renal injury in rats.
    Clinical science (London, England : 1979), 2020, 12-11, Volume: 134, Issue:23

    Topics: Acute Kidney Injury; Angiotensin-Converting Enzyme 2; Animals; Biomarkers; Body Weight; Cytokines; D

2020
Nephroprotective potential of Anogeissus latifolia Roxb. (Dhava) against gentamicin-induced nephrotoxicity in rats.
    Journal of ethnopharmacology, 2021, Jun-12, Volume: 273

    Topics: Animals; Biomarkers; Combretaceae; Gene Expression Regulation; Gentamicins; Inflammation; Interleuki

2021
Gentamicin Induced Microbiome Adaptations Associate With Increased BCAA Levels and Enhance Severity of Influenza Infection.
    Frontiers in immunology, 2020, Volume: 11

    Topics: Adaptation, Biological; Amino Acids, Branched-Chain; Animals; CD11b Antigen; CD8-Positive T-Lymphocy

2020
Daphnetin ameliorated GM-induced renal injury through the suppression of oxidative stress and apoptosis in mice.
    International immunopharmacology, 2021, Volume: 96

    Topics: Acute Kidney Injury; Animals; Antioxidants; Apoptosis; Cell Line; Cell Survival; Epithelial Cells; G

2021
HPLC-ESI/MS profiling, phytoconstituent isolation and evaluation of renal function, oxidative stress and inflammation in gentamicin-induced nephrotoxicity in rats of Ficus spragueana Mildbr. & Burret.
    Biomedical chromatography : BMC, 2021, Volume: 35, Issue:9

    Topics: Acute Kidney Injury; Animals; Antioxidants; Chromatography, High Pressure Liquid; Disease Models, An

2021
Anthocyanin-rich Riceberry bran extract attenuates gentamicin-induced hepatotoxicity by reducing oxidative stress, inflammation and apoptosis in rats.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 92

    Topics: Animals; Anthocyanins; Apoptosis; Chemical and Drug Induced Liver Injury; Gentamicins; Inflammation;

2017
Ultrahigh dose gentamicin alters inflammation and angiogenesis in vivo and in vitro.
    Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society, 2017, Volume: 25, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Burns; Cell Proliferation; Disease Models, Animal; Dose-Response Rel

2017
Protective effect of alpha-linolenic acid on gentamicin-induced ototoxicity in mice.
    Somatosensory & motor research, 2017, Volume: 34, Issue:3

    Topics: Accidental Falls; alpha-Linolenic Acid; Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Ap

2017
Concurrent administration effect of antibiotic and anti-inflammatory drugs on the immunotoxicity of bacterial endotoxins.
    International immunopharmacology, 2017, Volume: 52

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Dexamethasone; Drug Therapy, Combination;

2017
RomA, A Periplasmic Protein Involved in the Synthesis of the Lipopolysaccharide, Tunes Down the Inflammatory Response Triggered by Brucella.
    The Journal of infectious diseases, 2018, 03-28, Volume: 217, Issue:8

    Topics: Animals; Bacterial Proteins; Brucella; Brucellosis; Gentamicins; Inflammation; Lipopolysaccharides;

2018
Vitamin D supplementation may improve symptoms in Meniere's disease.
    Medical hypotheses, 2018, Volume: 116

    Topics: Anti-Bacterial Agents; Autoimmunity; Cytokines; Dietary Supplements; Gentamicins; Humans; Inflammati

2018
Candesartan and epigallocatechin-3-gallate ameliorate gentamicin-induced renal damage in rats through p38-MAPK and NF-κB pathways.
    Journal of biochemical and molecular toxicology, 2019, Volume: 33, Issue:3

    Topics: Animals; Benzimidazoles; Biphenyl Compounds; Caspase 3; Catechin; Drug Therapy, Combination; Gene Ex

2019
Amelioration of renal and hepatic function, oxidative stress, inflammation and histopathologic damages by Malva sylvestris extract in gentamicin induced renal toxicity.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2019, Volume: 112

    Topics: Animals; Dose-Response Relationship, Drug; Gentamicins; Inflammation; Kidney; Kidney Diseases; Kidne

2019
No Fever, No Murmur, No Problem? A Concealed Case of Infective Endocarditis.
    The Journal of emergency medicine, 2019, Volume: 57, Issue:2

    Topics: Adult; Amphetamine; Analgesics, Opioid; Anti-Bacterial Agents; C-Reactive Protein; Endocarditis; Eno

2019
Inflammation up-regulates cochlear expression of TRPV1 to potentiate drug-induced hearing loss.
    Science advances, 2019, Volume: 5, Issue:7

    Topics: Aminoglycosides; Animals; Calcium; Cell Survival; Cells, Cultured; Disease Models, Animal; Gene Expr

2019
Macrophage-stimulating protein attenuates gentamicin-induced inflammation and apoptosis in human renal proximal tubular epithelial cells.
    Biochemical and biophysical research communications, 2013, May-10, Volume: 434, Issue:3

    Topics: Apoptosis; Cell Line; Epithelial Cells; Flow Cytometry; Gentamicins; Hepatocyte Growth Factor; Human

2013
Acute kidney injury following unselected emergency admission: role of the inflammatory response, medication and co-morbidity.
    Nephron. Clinical practice, 2014, Volume: 126, Issue:1

    Topics: Academic Medical Centers; Acute Kidney Injury; Adult; Aged; Aged, 80 and over; Amphotericin B; C-Rea

2014
NOD2/RICK-dependent β-defensin 2 regulation is protective for nontypeable Haemophilus influenzae-induced middle ear infection.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Animals; beta-Defensins; Cell Line; Cytoplasm; Ear, Middle; Endocytosis; Gene Expression Regulation;

2014
Vasitis: the need for imaging and clinical acumen.
    BMJ case reports, 2014, Oct-17, Volume: 2014

    Topics: Anti-Bacterial Agents; Ciprofloxacin; Clindamycin; Diagnosis, Differential; Follow-Up Studies; Genit

2014
Beetroot (Beta vulgaris L.) extract ameliorates gentamicin-induced nephrotoxicity associated oxidative stress, inflammation, and apoptosis in rodent model.
    Mediators of inflammation, 2014, Volume: 2014

    Topics: Animals; Apoptosis; Arab World; Beta vulgaris; Catalase; Cytokines; Disease Models, Animal; Female;

2014
Rutin attenuates gentamicin-induced renal damage by reducing oxidative stress, inflammation, apoptosis, and autophagy in rats.
    Renal failure, 2015, Volume: 37, Issue:3

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Apoptosis; Autophagy; Disease Models, Animal; Genta

2015
Rapamycin protects against gentamicin-induced acute kidney injury via autophagy in mini-pig models.
    Scientific reports, 2015, Jun-08, Volume: 5

    Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Apoptosis; Autophagy; Disease Models, Animal; G

2015
Development and in vitro evaluation of infection resistant materials: A novel surface modification process for silicone and Dacron.
    Journal of biomaterials applications, 2016, Volume: 30, Issue:7

    Topics: Acrylates; Animals; Cell Adhesion; Collagen; Escherichia coli; Fibroblasts; Foreign-Body Reaction; G

2016
Sinapic acid mitigates gentamicin-induced nephrotoxicity and associated oxidative/nitrosative stress, apoptosis, and inflammation in rats.
    Life sciences, 2016, Nov-15, Volume: 165

    Topics: Animals; Apoptosis; Coumaric Acids; Cytokines; Gentamicins; Inflammation; Kidney; Male; Nitrosation;

2016
Nephro-protective effect of a novel formulation of unopened coconut inflorescence sap powder on gentamicin induced renal damage by modulating oxidative stress and inflammatory markers.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 85

    Topics: Animals; Anti-Bacterial Agents; Antioxidants; Biomarkers; Cocos; Flowers; Gentamicins; Inflammation;

2017
Diallyl sulfide enhances antioxidants and inhibits inflammation through the activation of Nrf2 against gentamicin-induced nephrotoxicity in Wistar rats.
    European journal of pharmacology, 2009, Mar-15, Volume: 606, Issue:1-3

    Topics: Allyl Compounds; Animals; Anti-Inflammatory Agents; Antioxidants; Ascorbic Acid; Biomarkers; Enzyme

2009
Development of intraosseous infusion of the distal phalanx to access the foot lamellar circulation in the standing, conscious horse.
    Veterinary journal (London, England : 1997), 2010, Volume: 183, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Bone Screws; Consciousness; Foot Diseases; Forelimb; Gentamicins; Ho

2010
Effect of catheter-lock solutions on catheter-related infection and inflammatory syndrome in hemodialysis patients: heparin versus citrate 46% versus heparin/gentamicin.
    Blood purification, 2010, Volume: 29, Issue:3

    Topics: Aged; Anti-Bacterial Agents; C-Reactive Protein; Catheter-Related Infections; Catheterization, Centr

2010
Inhibition of cystathionine gamma-lyase and the biosynthesis of endogenous hydrogen sulphide ameliorates gentamicin-induced nephrotoxicity.
    European journal of pharmacology, 2012, Jun-15, Volume: 685, Issue:1-3

    Topics: Alkynes; Animals; Anti-Bacterial Agents; Cystathionine gamma-Lyase; Female; Gentamicins; Glycine; Hy

2012
Hypoxia-inducible factor activation protects the kidney from gentamicin-induced acute injury.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: Acute Kidney Injury; Amino Acids, Dicarboxylic; Animals; Apoptosis; Caspase 3; Caspase 9; Cells, Cul

2012
Systemic inflammatory response induced by dacron graft and modulation by antimicrobial agents: experimental study.
    The Journal of surgical research, 2002, Volume: 107, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Bacterial Physiological Phenomena; Cefa

2002
Effect of composition of interpenetrating polymer network hydrogels based on poly(acrylic acid) and gelatin on tissue response: a quantitative in vivo study.
    Journal of biomedical materials research. Part A, 2004, Feb-01, Volume: 68, Issue:2

    Topics: Acrylic Resins; Animals; Anti-Bacterial Agents; Biocompatible Materials; Gelatin; Gentamicins; Granu

2004
Hydrogel probe for iontophoresis drug delivery to the eye.
    Journal of biomaterials science. Polymer edition, 2004, Volume: 15, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Dextrans; Drug Carriers; Eye; Eye Diseases; Galactans; Gentamicins;

2004
[Results of intraocular administration of gentamicin in suppurative endophthalmitis].
    Oftalmologicheskii zhurnal, 1983, Volume: 38, Issue:2

    Topics: Adolescent; Adult; Child; Conjunctiva; Corneal Injuries; Eye Injuries; Follow-Up Studies; Gentamicin

1983
Determination of cerebrospinal fluid gentamicin in the beagle using an indwelling cerebral ventricular cannula.
    Chemotherapy, 1981, Volume: 27, Issue:5

    Topics: Animals; Catheterization; Cerebral Ventricles; Dogs; Gentamicins; Inflammation; Kinetics

1981
The role of the fibrous capsule in the function of implanted drug-polymer sustained release systems.
    Journal of biomedical materials research, 1981, Volume: 15, Issue:6

    Topics: Animals; Capsules; Dogs; Drug Implants; Gentamicins; Granulation Tissue; Inflammation; Muscles; Sili

1981
Comparison of endotoxin release by different antimicrobial agents and the effect on inflammation in experimental Escherichia coli meningitis.
    The Journal of infectious diseases, 1993, Volume: 168, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Cefotaxime; Cefpirome; Cephalosporins; Chloramphenicol; Endotoxins;

1993
[Effect of drugs of various groups on the course of experimental local pyo-inflammatory processes].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1995, Volume: 40, Issue:10

    Topics: Adrenergic Agents; Adrenergic beta-Antagonists; Animals; Anti-Bacterial Agents; Anticoagulants; Bact

1995
Intraventricular and parenteral gentamicin therapy for ventriculitis in children.
    American journal of diseases of children (1960), 1978, Volume: 132, Issue:5

    Topics: Cerebral Ventricles; Cerebrospinal Fluid Shunts; Child; Child, Preschool; Drug Resistance, Microbial

1978
Postoperative ventriculitis in infants.
    Acta neurochirurgica, 1975, Volume: 32, Issue:1-2

    Topics: Cerebrospinal Fluid; Cerebrospinal Fluid Shunts; Child, Preschool; Encephalitis; Female; Gentamicins

1975
[Use of garamycin and gentamicin preparations in obstetrics and gynecology].
    Ginekologia polska, 1975, Volume: 46, Issue:8

    Topics: Cephalothin; Drug Therapy, Combination; Female; Genital Diseases, Female; Gentamicins; Humans; Infec

1975
Further observations on the diagnosis, etiology, and treatment of endophthalmitis.
    Transactions of the American Ophthalmological Society, 1975, Volume: 73

    Topics: Anterior Chamber; Cephaloridine; Electroretinography; Eye Diseases; Gentamicins; Humans; Inflammatio

1975
Effect of local hemostatics on bone induction in rats: a comparative study of bone wax, fibrin-collagen paste, and bioerodible polyorthoester with and without gentamicin.
    Journal of biomedical materials research, 1992, Volume: 26, Issue:6

    Topics: Absorption; Animals; Biocompatible Materials; Bone and Bones; Collagen; Drug Combinations; Fibrin; G

1992
[Prevention of postoperative infectious complications with suture materials containing gentamicin].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 1991, Volume: 36, Issue:5

    Topics: Animals; Bacterial Infections; Dogs; Gentamicins; Inflammation; Postoperative Complications; Sutures

1991
[Kinetics of gentamycin in the treatment of newborn infants with infectious-inflammatory diseases].
    Pediatriia, 1989, Issue:10

    Topics: Drug Evaluation; Gentamicins; Humans; Infant, Newborn; Infections; Inflammation

1989
Multistrain comparison of three antimicrobial prophylaxis regimens in experimental postoperative Pseudomonas endophthalmitis.
    American journal of ophthalmology, 1985, Sep-15, Volume: 100, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Cefazolin; Cefepime; Ceftazidime; Cephalosporins; Drug Combinations;

1985
Intravitreal injection of dexamethasone. Treatment of experimentally induced endophthalmitis.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1974, Volume: 92, Issue:2

    Topics: Abscess; Animals; Dexamethasone; Drug Therapy, Combination; Electroretinography; Exudates and Transu

1974
The dizzy patient.
    Postgraduate medicine, 1972, Volume: 52, Issue:2

    Topics: Diazepam; Drainage; Ear; Ear Neoplasms; Ethacrynic Acid; Gentamicins; Hearing Disorders; Humans; Inf

1972
Treatment of chondritis in the burned ear by the local instillation of antibiotics.
    Plastic and reconstructive surgery, 1974, Volume: 53, Issue:2

    Topics: Anti-Bacterial Agents; Burns; Cartilage; Drug Therapy, Combination; Ear, External; Gentamicins; Huma

1974
Tissue antibiotic penetration in streptococcal gangrene.
    The Johns Hopkins medical journal, 1973, Volume: 133, Issue:1

    Topics: Amputation, Surgical; Anti-Bacterial Agents; Cephalothin; Debridement; Gangrene; Gentamicins; Humans

1973
Treatment of ventriculitis with gentamicin in an infant born with spina bifida.
    Scandinavian journal of infectious diseases, 1972, Volume: 4, Issue:2

    Topics: Cerebral Ventricles; Escherichia coli; Female; Gentamicins; Humans; Infant, Newborn; Infant, Newborn

1972
Ocular tissue absorption of gentamicin.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1970, Volume: 84, Issue:6

    Topics: Absorption; Animals; Aqueous Humor; Conjunctiva; Cornea; Eye; Eye Diseases; Gentamicins; Inflammatio

1970