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gentamicin and Infections, Prosthesis-Related

gentamicin has been researched along with Infections, Prosthesis-Related in 255 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Research Excerpts

ExcerptRelevanceReference
"An 83-year-old man developed acute kidney failure after intra-articular use of gentamicin sponges for a periprosthetic hip infection."7.96Acute kidney failure after intra-articular use of gentamicin sponge. ( Aarnoudse, ALHJ; Gommans, EPAT; Grouls, RJE; van der Linden, CMJ; van Erp-van Boekel, AAW; van Wensen, RJA, 2020)
"Antibiotic-loaded bone cement (ALBC) spacers are the mainstay in 2-stage revision, but antibiotics (vancomycin plus aminoglycosides) may undergo systemic absorption, resulting in acute kidney injury (AKI)."5.41Nephrotoxicity Related to Antibiotic-Loaded Spacers in a 2-Stage Revision for Periprosthetic Joint Infection. ( Benito, J; Corces, A; Higuera, CA; Judd, H; Pannu, TS; Villa, JM, 2023)
"An 83-year-old man developed acute kidney failure after intra-articular use of gentamicin sponges for a periprosthetic hip infection."3.96Acute kidney failure after intra-articular use of gentamicin sponge. ( Aarnoudse, ALHJ; Gommans, EPAT; Grouls, RJE; van der Linden, CMJ; van Erp-van Boekel, AAW; van Wensen, RJA, 2020)
" Systemic antibiotics often do not reach "dead-space" hematomas where bacteria harbor after surgery, whereas local, controlled release gentamicin prophylaxis through PLGA microspheres showed favorable pharmacokinetics data to achieve local bactericidal concentrations for up to 7 days after surgery."3.75Reduction of postoperative spinal implant infection using gentamicin microspheres. ( Becker, E; Gelb, D; Ludwig, SC; Poelstra, KA; Stall, AC, 2009)
" Both of these characteristics were compared with those of commercially available gentamicin-loaded poly(methylmethacrylate) (PMMA) beads, which are commonly used in the local treatment of osteomyelitis."3.75A biodegradable antibiotic delivery system based on poly-(trimethylene carbonate) for the treatment of osteomyelitis. ( Busscher, HJ; Crielaard, BJ; Grijpma, DW; Kluin, OS; Neut, D; van der Mei, HC, 2009)
"To evaluate a new gentamicin-vancomycin- impregnated (2:1) PMMA coating nail as a drug delivery device to treat bone and intramedullary infections, methicillin-resistant Staphylococcus aureus (MRSA) was used to induce femoral osteomyelitis in 20 New Zealand male rabbits."3.74Preliminary investigations on a new gentamicin and vancomycin-coated PMMA nail for the treatment of bone and intramedullary infections: An experimental study in the rabbit. ( Borsari, V; Fini, M; Gaibani, P; Giardino, R; Giavaresi, G; Sambri, V; Soffiatti, R, 2008)
"Vancomycin was added by manually mixing with PMMA bone cement."2.78Release of gentamicin and vancomycin from preformed spacers in infected total hip arthroplasties: measurement of concentrations and inhibitory activity in patients' drainage fluids and serum. ( Benini, A; Bondi, M; Magnan, B; Regis, D; Samaila, E; Sandri, A, 2013)
"The purpose of this study was to assess the systemic safety and potential adverse effects of using a high-dose antibiotic-impregnated cement spacer after resection arthroplasty of an infected total knee replacement."2.71Systemic safety of high-dose antibiotic-loaded cement spacers after resection of an infected total knee arthroplasty. ( Haidukewych, GJ; Hanssen, AD; Jacofsky, DJ; Lee, GC; Osmon, D; Springer, BD, 2004)
"Left psoas abscess associated with endograft infection caused by bacteremia of Listeria monocytogenes."2.61Psoas abscess associated with aortic endograft infection caused by bacteremia of Listeria monocytogenes: A case report and literature review (CARE Complaint). ( Hu, SY; Lin, TC; Ma, JW; Tsai, CA, 2019)
"Endocarditis is a rare manifestation of Yersinia enterocolitica infection."2.39Yersinia enterocolitica endocarditis: case report and literature review. ( Antoniadou, A; Giamarellou, H; Kanatakis, S; Kanavos, K; Papadaki, K; Papaioannou, C, 1995)
" Due to the low local bioavailability of systemic antibiotics and possible off-target effects, localized drug delivery systems are of great importance."1.91Electrophoretic deposition of gentamicin and chitosan into titanium nanotubes to target periprosthetic joint infection. ( Angenendt, K; Chiesa, R; Della Fara, G; Fischer, A; Hamilton, JL; Markovics, A; Radice, S; Sturm, A; Wimmer, MA, 2023)
" The doses and duration of SAP used varied from one single preoperative dosage as standard practice in Bolzano, Italy (98%) to 1-day 4 doses in Norway (83% of the 40,709 TKAs reported to the Norwegian arthroplasty register)."1.91The use of antibiotic-loaded bone cement and systemic antibiotic prophylactic use in 2,971,357 primary total knee arthroplasties from 2010 to 2020: an international register-based observational study among countries in Africa, Europe, North America, and O ( Armaroli, C; Armstrong, R; Ashforth, JA; Brand, C; Bülow, E; Chang, RN; Christen, B; Dale, H; De Steiger, R; Dragomirescu, D; Fenstad, AM; Frampton, C; Furnes, O; Gjertsen, JE; Grimberg, A; Hakulinen, E; Hallan, G; Harries, D; Illgen, R; Leta, TH; Lie, SA; Lindberg-Larsen, M; Lutro, O; Lygre, SHL; Mäkelä, K; Molinari, M; Mullen, K; Nelissen, RGHH; Paxton, EW; Pedersen, AB; Picus, R; Prentice, HA; Rolfson, O; Shapiro, J; Steinbrück, A; Stoica, IC; Van Steenbergen, LN; Vorovenci, AE; W-Dahl, A; Wilkinson, JM; Willis, J; Wooster, K; Wu, Y; Wyatt, M, 2023)
"Gentamicin-loaded UHMWPE was prepared using phase-separated compression moulding, and its drug elution kinetics, antibacterial, mechanical, and wear properties were compared with those of conventional gentamicin-loaded bone cement."1.56Addressing prosthetic joint infections via gentamicin-eluting UHMWPE spacer. ( Atici, AE; Connolly, RL; Gil, D; Hugard, S; Muratoglu, OK; Oral, E; Shuvaev, S; Wannomae, KK, 2020)
"A vancomycin antibody was detected and anemia resolved after vancomycin was discontinued."1.48Drug-induced immune hemolytic anemia associated with anti-vancomycin complicated by a paraben antibody. ( Arndt, PA; Cheng, EY; Gniadek, TJ; Leger, RM; Zantek, ND; Zydowicz, D, 2018)
"Vancomycin levels were obtained, local from drains and systemic from blood samples, on postoperative days 1 to 5."1.46Superficial Vancomycin Coating of Bone Cement in Orthopedic Revision Surgery: A Safe Technique to Enhance Local Antibiotic Concentrations. ( Amerstorfer, F; Fischerauer, S; Glehr, M; Kuehn, KD; Leithner, A; Sadoghi, P; Schwantzer, G, 2017)
"Gentamicin was detectable over a time period of 42 days in the endosteum, up to seven days in the kidney, up to 4 h in the bone and at the end of the experiment on one of eight wires."1.43In vivo quantification of gentamicin released from an implant coating. ( Beck, S; Bormann, N; Fassbender, M; Lucke, M; Montali, A; Nast, S; Schmidmaier, G; Wildemann, B, 2016)
"Gentamicin and V were released from spacers at bactericidal concentrations exerting a strong inhibition against methicillin-resistant Staphylococcus aureus (MRSA) and coagulase-negative staphylococci (CoNS) strains."1.42Antimicrobial activity of gentamicin and vancomycin combination in joint fluids after antibiotic-loaded cement spacer implantation in two-stage revision surgery. ( Benini, A; Bertazzoni Minelli, E; Bondi, M; Magnan, B; Samaila, E, 2015)
"(1) Gentamicin release was sustained over 7 days with the higher-dose formulation release profile similar to release from high-dose antimicrobial-loaded bone cement."1.42Local gentamicin delivery from resorbable viscous hydrogels is therapeutically effective. ( Calara, F; McLaren, A; McLemore, R; Overstreet, D; Vernon, B, 2015)
" PMMA cylinders loaded with daptomycin alone or in combination with gentamicin or PEG600, vancomycin and gentamicin were incubated with S."1.42Activity of bone cement loaded with daptomycin alone or in combination with gentamicin or PEG600 against Staphylococcus epidermidis biofilms. ( Bétrisey, B; Borens, O; Furustrand Tafin, U; Peñalba Arias, P; Trampuz, A; Vogt, S, 2015)
"Gentamicin was eluted from 41 discrete sites over the surfaces of six spacer components and compared with elution from 15 ALBC specimens, five from each of three hand-mixed formulations."1.42Antimicrobial Release From Prefabricated Spacers Is Variable and the Dose Is Low. ( Galli, C; Goltzer, O; McLaren, A; McLemore, R; Overstreet, D, 2015)
"One patient died of septic shock."1.37Management of septic complications following modular endoprosthetic reconstruction of the proximal femur. ( Dominkus, M; Funovics, PT; Hipfl, C; Hofstaetter, JG; Kotz, RI; Puchner, S, 2011)
"Treating septic arthritis of the hip with coexisting advanced degenerative disease is challenging."1.37An articulating antibiotic spacer controls infection and improves pain and function in a degenerative septic hip. ( Beauchamp, CP; Fleck, EE; Rapuri, VR; Spangehl, MJ, 2011)
"Gentamicin sponges were used in four cases of periprosthetic infections."1.37Use of gentamicin collagen sponges for the treatment of periprosthetic breast implant infection. ( Lapid, O, 2011)
"Gentamicin was released rapidly with an initial burst in aqueous solution and followed by a slow release."1.36Gentamycin delivered from a PDLLA coating of metallic implants: In vivo and in vitro characterisation for local prophylaxis of implant-related osteomyelitis. ( Lucke, M; Schmidmaier, G; Stöckle, U; Vester, H; Wildemann, B, 2010)
"Gentamicin release was determined using high-per-formance liquid chromatography mass spectrometry."1.35In vitro testing of chitosan in gentamicin-loaded bone cement: no antimicrobial effect and reduced mechanical performance. ( Brady, A; Buchanan, F; Dunne, N; Hill, J; Newe, C; Tunney, M; Walker, G, 2008)
"The exposure of human osteoblasts and endothelial cells to polyhexanide at concentrations with questionable antibacterial activity resulted in severe cell damage whereas exposure to high dosed gentamicin did not."1.34Effect of polyhexanide and gentamycin on human osteoblasts and endothelial cells. ( Eulert, J; Hendrich, C; Ince, A; Jakob, F; Löhr, JF; Schütze, N, 2007)
"elongata in a patient with Klinefelter's syndrome."1.34Prosthetic valve endocarditis due to Neisseria elongata subsp. elongata in a patient with Klinefelter's syndrome. ( Evans, M; Malnick, H; Shah, JJ; Turner, DPJ; Yazdani, F, 2007)
"When gentamicin was added to unloaded cement (1-4 g), there was a significant reduction in the mechanical performance of the loaded cements compared to unloaded cement."1.34In vitro study of the efficacy of acrylic bone cement loaded with supplementary amounts of gentamicin: effect on mechanical properties, antibiotic release, and biofilm formation. ( Dunne, N; Hill, J; Kirkpatrick, R; McAfee, P; Patrick, S; Todd, K; Tunney, M, 2007)
"Standard treatment of bacterial endocarditis with penicillin and gentamicin was effective in both patients."1.33Infective endocarditis due to Abiotrophia defectiva: a report of two cases. ( Gasparac, I; Lainscak, M; Lejko-Zupanc, T; Mueller-Premru, M; Pirs, M; Strumbelj, I, 2005)
"Gentamicin was bound to vascular prostheses in the amount of 12g per kg of prosthesis."1.33Antibacterial activity of gentamicin-bonded gelatin-sealed polyethylene terephthalate vascular prostheses. ( Belcarz, A; Ginalska, G; Osinska, M; Rzeski, W; Urbanik-Sypniewska, T; Uryniak, A; Wolski, A, 2005)
"Gentamicin was immobilized to four types of matrix: silica gel and porous glass beads activated by either silanization (APTES) or by adhesively bound keratin (with immobilization yield ranging from 36."1.32A covalent method of gentamicin bonding to silica supports. ( Ginalska, G; Osińska, M; Uryniak, A, 2004)
"More gentamicin was released from CMW3 (79 mg) than from Palacos R (70 mg), but the percentage gentamicin released after one week relative to the total amount incorporated was significantly lower for CMW3 (4."1.31Gentamicin release from polymethylmethacrylate bone cements and Staphylococcus aureus biofilm formation. ( Busscher, HJ; Neut, D; Schenk, W; van de Belt, H; van der Mei, HC; van Horn, JR, 2000)
"Gentamicin-loaded beads were retrieved from 20 patients with prosthesis-related infections."1.31Biomaterial-associated infection of gentamicin-loaded PMMA beads in orthopaedic revision surgery. ( Busscher, HJ; Neut, D; Stokroos, I; van de Belt, H; van der Mei, HC; van Horn, JR, 2001)
"One patient had a recurrence of infection and was treated with resection arthroplasty."1.31Impregnation of vancomycin, gentamicin, and cefotaxime in a cement spacer for two-stage cementless reconstruction in infected total hip arthroplasty. ( Chang, JD; Cho, SH; Ha, YC; Kim, SY; Kim, YH; Koo, KH; Park, HB; Song, HR; Yang, JW, 2001)
"aureus)."1.29Palacos gentamicin for the treatment of deep periprosthetic hip infections. ( Brause, BD; Evans, BG; Garvin, KL; Salvati, EA, 1994)

Research

Studies (255)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's36 (14.12)18.2507
2000's77 (30.20)29.6817
2010's107 (41.96)24.3611
2020's35 (13.73)2.80

Authors

AuthorsStudies
Jenny, JY1
Hamon, M1
Klein, S1
Reiter-Schatz, A1
Rondé-Oustau, C1
Boéri, C1
Wisniewski, S1
Gaudias, J1
Huguet, S1
Bernaus, M1
Gómez, L1
Cuchí, E1
Soriano, A2
Font-Vizcarra, L1
Michalicha, A1
Espona-Noguera, A1
Canal, C1
Budzyńska, B1
Pięt, M1
Przywara, S1
Pawelec, J1
Belcarz, A3
Xu, T1
Wu, KL1
Jie, K1
Judd, H1
Benito, J1
Pannu, TS1
Villa, JM1
Higuera, CA1
Corces, A1
Hu, L1
Fu, J1
Zhou, Y1
Chai, W1
Zhang, G1
Hao, L1
Chen, J1
Mukka, S1
Hailer, NP1
Möller, M1
Gordon, M1
Lazarinis, S1
Rogmark, C1
Östlund, O1
Sköldenberg, O1
Wolf, O1
Lunz, A2
Knappe, K2
Omlor, GW2
Schonhoff, M2
Renkawitz, T2
Jaeger, S2
Ashkenazi, I1
Amzallag, N1
Snir, N1
Morgan, S1
Garceau, S1
Kotz, L1
Gold, A1
Warschawski, Y1
Janssen, DMC1
Willems, P1
Geurts, J1
Arts, CJJ1
Matteucci, A1
Bonanni, M1
Massaro, G1
Chiricolo, G1
Stifano, G1
Forleo, GB1
Biondi-Zoccai, G1
Sangiorgi, G1
Della Fara, G1
Markovics, A1
Radice, S1
Hamilton, JL1
Chiesa, R2
Sturm, A1
Angenendt, K1
Fischer, A1
Wimmer, MA1
Hiddema, JS1
Leta, TH1
Fenstad, AM1
Lygre, SHL1
Lie, SA1
Lindberg-Larsen, M1
Pedersen, AB1
W-Dahl, A2
Rolfson, O1
Bülow, E1
Ashforth, JA1
Van Steenbergen, LN1
Nelissen, RGHH1
Harries, D1
De Steiger, R1
Lutro, O1
Hakulinen, E1
Mäkelä, K1
Willis, J1
Wyatt, M1
Frampton, C1
Grimberg, A1
Steinbrück, A1
Wu, Y1
Armaroli, C1
Molinari, M1
Picus, R1
Mullen, K1
Illgen, R1
Stoica, IC1
Vorovenci, AE1
Dragomirescu, D1
Dale, H1
Brand, C1
Christen, B1
Shapiro, J1
Wilkinson, JM1
Armstrong, R1
Wooster, K1
Hallan, G1
Gjertsen, JE1
Chang, RN1
Prentice, HA1
Paxton, EW1
Furnes, O1
Bangert, Y1
Lehner, B1
Corró, S2
Vicente, M3
Rodríguez-Pardo, D3
Pigrau, C2
Lung, M1
Corona, PS5
Auñón, Á1
Esteban, J3
Doadrio, AL2
Boiza-Sánchez, M1
Mediero, A1
Eguibar-Blázquez, D1
Cordero-Ampuero, J2
Conde, A2
Arenas, MÁ2
de-Damborenea, JJ2
Aguilera-Correa, JJ2
Ma, JW1
Hu, SY1
Lin, TC1
Tsai, CA1
Gil, D2
Daffinee, K1
Friedman, R1
Bhushan, B1
Muratoglu, OK2
LaPlante, K1
Oral, E2
Sohail, MR1
Esquer Garrigos, Z1
Elayi, CS1
Xiang, K1
Catanzaro, JN1
Allen, B1
Moore, C1
Seyler, T1
Gall, K1
Atici, AE1
Connolly, RL1
Hugard, S1
Shuvaev, S1
Wannomae, KK1
Gommans, EPAT1
Aarnoudse, ALHJ1
van Wensen, RJA1
van Erp-van Boekel, AAW1
Grouls, RJE1
van der Linden, CMJ1
Ngaage, LM1
Elegbede, A1
Brao, K1
Chopra, K1
Gowda, AU1
Nam, AJ1
Ernst, RK1
Shirtliff, ME1
Harro, J1
Rasko, YM1
Thomas, B1
Benedikt, M1
Alamri, A1
Kapp, F1
Bader, R2
Summer, B1
Thomas, P1
Oppel, E1
Schmitt, DR1
Killen, C1
Murphy, M1
Perry, M1
Romano, J1
Brown, N1
Li, YD1
MaiMaiTiABuDuLa, M1
Cao, GQ1
MaiMaiTiAiLi, M1
Zhou, XH1
Lu, YM1
Zhang, JH1
Xing, Q1
Wu, CJ1
Feng, M1
Zhang, GG1
Tang, BP1
Ferlic, PW1
Nogler, M1
Weinberg, AM2
Kühn, KD2
Liebensteiner, M1
Coraça-Huber, DC1
Wang, L2
Tkhilaishvili, T1
Bernal Andres, B1
Trampuz, A7
Gonzalez Moreno, M1
Carrera, L2
Bidossi, A1
Bottagisio, M1
Logoluso, N2
De Vecchi, E1
Foster, AL1
Boot, W1
Stenger, V1
D'Este, M1
Jaiprakash, A1
Eglin, D1
Zeiter, S1
Richards, RG2
Moriarty, TF2
Nichol, T2
Callaghan, J1
Townsend, R2
Stockley, I2
Hatton, PV1
Le Maitre, C1
Smith, TJ1
Akid, R1
Dagneaux, L1
Limberg, AK1
Osmon, DR2
Leung, N1
Berry, DJ2
Abdel, MP2
Walter, N1
Popp, D1
Freigang, V1
Nerlich, M1
Alt, V1
Rupp, M1
Tootsi, K1
Heesen, V1
Lohrengel, M1
Enz, AE1
Illiger, S1
Mittelmeier, W2
Lohmann, CH1
Ortola, DJ1
Fenga, D1
Marcellino, S1
Rosi, M1
Centofanti, F1
Rosa, MA1
Ramírez Hidalgo, M1
Jover-Sáenz, A1
García-González, M1
Barcenilla-Gaite, F1
Anagnostakos, K3
Meyer, C1
Khan, ZA1
Hollenberg, SM1
Gniadek, TJ1
Arndt, PA1
Leger, RM1
Zydowicz, D1
Cheng, EY1
Zantek, ND1
Staats, K1
Sevelda, F1
Kaider, A1
Böhler, C1
Sigmund, IK1
Puchner, SE1
Windhager, R2
Holinka, J1
Butini, ME1
Cabric, S1
Di Luca, M1
Edelstein, AI2
Okroj, KT2
Rogers, T2
Della Valle, CJ2
Sporer, SM2
Lalanza, M1
Amat, C1
Grubhofer, F1
Imam, MA1
Wieser, K1
Achermann, Y1
Meyer, DC1
Gerber, C1
Ramos-Martínez, A1
Muñoz Serrano, A1
de Alarcón González, A1
Muñoz, P1
Fernández-Cruz, A1
Valerio, M1
Fariñas, MC1
Gutiérrez-Cuadra, M1
Miró, JM1
Ruiz-Morales, J1
Sousa-Regueiro, D1
Montejo, JM1
Gálvez-Acebal, J1
HidalgoTenorio, C1
Domínguez, F1
Zeng, Q1
Zhu, Y1
Yu, B1
Sun, Y1
Ding, X1
Xu, C1
Wu, YW1
Tang, Z1
Xu, FJ1
Atıcı, T1
Şahin, N1
Çavun, S1
Özakin, C1
Kaleli, T1
Vallet-Regí, M1
Wouthuyzen-Bakker, M1
Löwik, CAM1
Knobben, BAS1
Zijlstra, WP1
Ploegmakers, JJW1
Mithoe, G1
Al Moujahid, A1
Kampinga, GA1
Jutte, PC1
Kanji, JN1
Saxinger, L1
Klinder, A1
Zaatreh, S1
Ellenrieder, M1
Redanz, S1
Podbielski, A1
Reichel, T1
Bösebeck, H1
Al Thaher, Y1
Yang, L1
Jones, SA1
Perni, S1
Prokopovich, P1
Abdelaziz, H1
von Förster, G1
Gehrke, T1
Citak, M1
Petis, SM1
Perry, KI1
Mabry, TM1
Hanssen, AD3
Boelch, SP1
Jordan, MC1
Arnholdt, J1
Steinert, AF1
Rudert, M1
Luedemann, M1
Mooney, JA1
Manasherob, R1
Smeriglio, P1
Bhutani, N1
Amanatullah, DF1
Çöbden, A1
Çamurcu, Y1
Bulut Çöbden, S1
Sofu, H1
Üçpunar, H1
Sevencan, A1
Demirel, H1
Kimna, C1
Deger, S1
Tamburaci, S1
Tihminlioglu, F1
Suchý, T1
Šupová, M1
Sauerová, P1
Hubálek Kalbáčová, M1
Klapková, E1
Pokorný, M1
Horný, L1
Závora, J1
Ballay, R1
Denk, F1
Sojka, M1
Vištejnová, L1
Zou, C1
Xu, BY1
Guo, WT1
Mu, WB1
Ji, BC1
Cao, L1
Arts, SH1
Boogaarts, HD1
van Lindert, EJ1
Stefánsdóttir, A1
Johansson, A1
Lidgren, L1
Wagner, P1
Gallo, J3
Bogdanová, K1
Šiller, M1
Švábová, M1
Lošťák, J1
Kolář, M2
Franko, B1
Vaillant, M1
Recule, C1
Vautrin, E1
Brion, JP1
Pavese, P1
Magnan, B5
Bondi, M4
Vecchini, E2
Samaila, E3
Maluta, T2
Dall'Oca, C2
Webb, JC1
Gbejuade, H1
Lovering, A1
Spencer, R1
Okapa, R1
Marczyński, W1
Kolbuszewski, A1
Barro, V1
Mendez, M1
Cáceres, E1
Flores, X2
Geurts, JA2
Janssen, DM2
Kessels, AG1
Walenkamp, GH3
Regis, D1
Sandri, A1
Benini, A4
Ahmad, SS1
Huber, K1
Evangelopoulos, DS1
Kleer, B1
Kohlhof, H2
Schär, M1
Eggli, S1
Kohl, S1
Prasad, N1
Paringe, V1
Kotwal, R1
Ghandour, A1
Morgan Jones, R1
Lovallo, J1
Helming, J1
Jafari, SM1
Owusu-Forfie, A1
Donovan, S1
Minnock, C1
Adib, F1
Bertazzoni Minelli, E3
Schmolders, J1
Hischebeth, GT1
Friedrich, MJ1
Randau, TM1
Wimmer, MD1
Molitor, E1
Gravius, S1
Espinal, L1
Larrosa, N1
Proček, T1
Ryšková, L1
Kučera, T1
Šrot, J1
Šponer, P1
Plíšková, L1
Wiegering, A1
Sinha, B1
Spor, L1
Klinge, U1
Steger, U1
Germer, CT1
Dietz, UA1
Overstreet, D2
McLaren, A2
Calara, F1
Vernon, B1
McLemore, R2
Chen, AF1
Parvizi, J1
Jennings, JA1
Cannon, TA1
Partridge, DG1
Boden, RA1
Fölsch, C2
Federmann, M2
Kuehn, KD4
Kittinger, C3
Kogler, S1
Zarfel, G2
Kerwat, M2
Braun, S1
Fuchs-Winkelmann, S2
Paletta, JR2
Roessler, PP2
Peñalba Arias, P1
Furustrand Tafin, U2
Bétrisey, B2
Vogt, S1
Borens, O1
Barjaktarović, R1
Radoičić, D1
Mitković, M1
Neut, D10
Dijkstra, RJ2
Thompson, JI2
Kavanagh, C1
van der Mei, HC11
Busscher, HJ11
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Clinical Trials (8)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
DAICY Trial - Dual vs. Single-Antibiotic Impregnated Cement in Hemiarthroplasty for Femoral Neck Fracture: A Register-based Cluster-randomized Cross-over Controlled Trial[NCT05164081]Phase 37,000 participants (Anticipated)Interventional2022-01-01Recruiting
Antibiotic Elution Profile and Outcomes in the Treatment of Prosthetic Joint Infections of the Knee[NCT06023238]10 participants (Anticipated)Observational2023-06-05Recruiting
Articulating Versus Static Antibiotic Loaded Spacers for the Treatment of Prosthetic Hip Infection[NCT01373099]80 participants (Actual)Interventional2011-08-31Completed
One Stage Versus Two Stage For Periprosthetic Hip And Knee Infection[NCT02734134]343 participants (Actual)Interventional2016-05-18Active, not recruiting
Application of Antibiotic Loaded Calcium Sulfate as Prophylaxis for Patients With Non Modifiable Risk Factors for Periprosthetic Joint Infections[NCT03976466]Phase 487 participants (Actual)Interventional2019-05-22Completed
Articulating Versus Static Antibiotic Loaded Spacers for the Treatment of Prosthetic Knee Infection[NCT01373112]68 participants (Actual)Interventional2011-12-31Completed
Topical Gentamicin and Vancomycin for Surgical Site Infection Prophylaxis in Patients Undergoing High-Risk Vascular Surgery[NCT04238923]Phase 2/Phase 3356 participants (Anticipated)Interventional2020-05-01Not yet recruiting
Results of the Staged Surgical Approach for Management of Infected Un-united Femoral Shaft Fractures in Adults[NCT04681846]40 participants (Anticipated)Observational2021-03-31Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Length of Stay as an Indicator of the Hospital Economic Burden

The length of stay is an important indicator of efficiency and hospital economic burden. The reduction in number of hospitalization days results in lower risk of infection and less medication side effects and decreased need of hospital supplies. The difference in the average days of hospitalization between both groups indirectly represents the economic cost spent by the hospital. (NCT03976466)
Timeframe: Surgical procedure day to hospital discharge.

InterventionDays (Mean)
Control Group15.25
Calcium Sulfate Study Group4.6

Reviews

18 reviews available for gentamicin and Infections, Prosthesis-Related

ArticleYear
Comprehensive meta-analysis of antibiotic-impregnated bone cement versus plain bone cement in primary total knee arthroplasty for preventing periprosthetic joint infection.
    Chinese journal of traumatology = Zhonghua chuang shang za zhi, 2022, Volume: 25, Issue:6

    Topics: Anti-Bacterial Agents; Arthritis, Infectious; Arthroplasty, Replacement, Knee; Bone Cements; Gentami

2022
Nephrotoxicity Related to Antibiotic-Loaded Spacers in a 2-Stage Revision for Periprosthetic Joint Infection.
    Orthopedics, 2023, Volume: 46, Issue:3

    Topics: Acute Kidney Injury; Anti-Bacterial Agents; Bone Cements; Gentamicins; Humans; Prosthesis-Related In

2023
Psoas abscess associated with aortic endograft infection caused by bacteremia of Listeria monocytogenes: A case report and literature review (CARE Complaint).
    Medicine, 2019, Volume: 98, Issue:45

    Topics: Aged; Ampicillin; Anti-Bacterial Agents; Aortic Aneurysm, Abdominal; Blood Vessel Prosthesis Implant

2019
Antibiotic Elution from Hip and Knee Acrylic Bone Cement Spacers: A Systematic Review.
    BioMed research international, 2017, Volume: 2017

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements; Gentamicins; Humans; Knee Joint

2017
Valvular Heart Disease in Adults: Infective Endocarditis.
    FP essentials, 2017, Volume: 457

    Topics: Anti-Bacterial Agents; Blood Culture; Carbapenems; Cefepime; Cephalosporins; Cross Infection; Echoca

2017
Route of antibiotic prophylaxis for prevention of cerebrospinal fluid-shunt infection.
    The Cochrane database of systematic reviews, 2019, 06-04, Volume: 6

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Cephalosporins; Cerebrospinal Fluid Shunts; Drug Admi

2019
Lactobacillus paracasei endocarditis in a consumer of probiotics.
    Medecine et maladies infectieuses, 2013, Volume: 43, Issue:4

    Topics: Aged; Amoxicillin; Anti-Bacterial Agents; Antimanic Agents; Arthroplasty, Replacement, Hip; Bacterem

2013
Antibiotic-loaded bone cement and periprosthetic joint infection.
    Journal of long-term effects of medical implants, 2014, Volume: 24, Issue:2-3

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement; Bone Cements; Diffusion; Gentamicins; Humans; Join

2014
Influence of implant properties and local delivery systems on the outcome in operative fracture care.
    Injury, 2016, Volume: 47, Issue:3

    Topics: Anti-Bacterial Agents; Bone Cements; Bone Plates; Fracture Fixation, Internal; Fracture Healing; Fra

2016
[Treatment of periprosthetic infections].
    Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2016, Volume: 87, Issue:10

    Topics: Algorithms; Biofilms; Chronic Disease; Combined Modality Therapy; Debridement; Gentamicins; Humans;

2016
The incidence of deep brain stimulator hardware infection: the effect of change in antibiotic prophylaxis regimen and review of the literature.
    British journal of neurosurgery, 2011, Volume: 25, Issue:5

    Topics: Adult; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Cohort Studies; Deep Brain S

2011
'To bead or not to bead?' Treatment of osteomyelitis and prosthetic joint-associated infections with gentamicin bead chains.
    International journal of antimicrobial agents, 2011, Volume: 38, Issue:5

    Topics: Gentamicins; Humans; Methylmethacrylates; Osteomyelitis; Prosthesis-Related Infections; Randomized C

2011
Infected endovascular aneurysm repair graft complicated by vertebral osteomyelitis.
    Journal of vascular surgery, 2012, Volume: 56, Issue:3

    Topics: Aged, 80 and over; Anti-Bacterial Agents; Aortic Aneurysm, Abdominal; Blood Vessel Prosthesis; Blood

2012
Prophylaxis and treatment of implant-related infections by local application of antibiotics.
    Injury, 2006, Volume: 37 Suppl 2

    Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Antibiotic Prophylaxis; Bacterial Infe

2006
[Prevention and therapy of prosthesis infections in the thoracic area].
    Zentralblatt fur Chirurgie, 1995, Volume: 120, Issue:8

    Topics: Animals; Anti-Bacterial Agents; Aorta, Thoracic; Bioprosthesis; Blood Vessel Prosthesis; Fibrin Tiss

1995
Yersinia enterocolitica endocarditis: case report and literature review.
    European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 1995, Volume: 14, Issue:2

    Topics: Ceftriaxone; Drug Therapy, Combination; Endocarditis, Bacterial; Gentamicins; Heart Valve Prosthesis

1995
Listeria endocarditis: current management and patient outcome--world literature review.
    Heart (British Cardiac Society), 1997, Volume: 77, Issue:4

    Topics: Aged; Ampicillin; Anti-Bacterial Agents; Endocarditis, Bacterial; Female; Gentamicins; Humans; Liste

1997
Gentamicin PMMA beads and other local antibiotic carriers in two-stage revision of total knee infection: a review.
    Journal of chemotherapy (Florence, Italy), 2001, Volume: 13 Spec No 1, Issue:1

    Topics: Anti-Bacterial Agents; Drug Carriers; Gentamicins; Humans; Knee Prosthesis; Microspheres; Polymethyl

2001

Trials

13 trials available for gentamicin and Infections, Prosthesis-Related

ArticleYear
Study protocol: The DAICY trial-dual versus single-antibiotic impregnated cement in primary hemiarthroplasty for femoral neck fracture-a register-based cluster-randomized crossover-controlled trial.
    Acta orthopaedica, 2022, 10-05, Volume: 93

    Topics: Anti-Bacterial Agents; Bone Cements; Clindamycin; Cross-Over Studies; Femoral Neck Fractures; Gentam

2022
A prospective comparison of four methods for preventing pacemaker pocket infections.
    Artificial organs, 2021, Volume: 45, Issue:4

    Topics: Aged; Anti-Bacterial Agents; Batroxobin; Female; Gentamicins; Humans; Male; Pacemaker, Artificial; P

2021
A preformed antibiotic-loaded spacer for treatment for septic arthritis of the shoulder.
    Musculoskeletal surgery, 2014, Volume: 98, Issue:1

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthritis, Infectious; Arthritis, Rheumatoid; Arthro

2014
Release of gentamicin and vancomycin from preformed spacers in infected total hip arthroplasties: measurement of concentrations and inhibitory activity in patients' drainage fluids and serum.
    TheScientificWorldJournal, 2013, Volume: 2013

    Topics: Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Body Fluids; Drainage; Drug Implants; D

2013
Measurements of in vivo intra-articular gentamicin levels from antibiotic loaded articulating spacers in revision total knee replacement.
    The Knee, 2009, Volume: 16, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Drug Carriers; Female; Gentamicins; Hu

2009
Preformed gentamicin spacers in two-stage revision hip arthroplasty: functional results and complications.
    International orthopaedics, 2011, Volume: 35, Issue:10

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; B

2011
Release of gentamicin and vancomycin from temporary human hip spacers in two-stage revision of infected arthroplasty.
    The Journal of antimicrobial chemotherapy, 2004, Volume: 53, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements; Drug Therapy, Combination

2004
Systemic safety of high-dose antibiotic-loaded cement spacers after resection of an infected total knee arthroplasty.
    Clinical orthopaedics and related research, 2004, Issue:427

    Topics: Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Bone Cements; Female; Follow-Up Studie

2004
A comparison of gentamicin-impregnated polymethylmethacrylate bead implantation to conventional parenteral antibiotic therapy in infected total hip and knee arthroplasty.
    Clinical orthopaedics and related research, 1993, Issue:295

    Topics: Adult; Aged; Anti-Bacterial Agents; Combined Modality Therapy; Debridement; Female; Gentamicins; Hip

1993
Prophylaxis with systematic antibiotics versus gentamicin bone cement in total hip arthroplasty. A ten-year survey of 1,688 hips.
    Clinical orthopaedics and related research, 1993, Issue:292

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bone Cements; Female; Follow-Up Studies; Gent

1993
A randomized prospective comparison of antibiotic tissue levels in the corpora cavernosa of patients undergoing penile prosthesis implantation using gentamicin plus cefazolin versus an oral fluoroquinolone for prophylaxis.
    The Journal of urology, 1996, Volume: 156, Issue:3

    Topics: Administration, Oral; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Cefazoli

1996
Antibiotic prophylaxis in prosthetic penile surgery: critical assessment of results in 75 consecutive patients.
    International journal of impotence research, 1996, Volume: 8, Issue:2

    Topics: Anti-Bacterial Agents; Evaluation Studies as Topic; Gentamicins; Humans; Male; Penile Prosthesis; Pe

1996
Gentamicin beads in vascular surgery: long-term results of implantation.
    Cardiovascular surgery (London, England), 1999, Volume: 7, Issue:4

    Topics: Aged; Aged, 80 and over; Antibiotic Prophylaxis; Blood Vessel Prosthesis Implantation; Drug Implants

1999

Other Studies

224 other studies available for gentamicin and Infections, Prosthesis-Related

ArticleYear
Cement Loaded With High-Dose Gentamicin and Clindamycin Reduces the Risk of Subsequent Infection After One-Stage Hip or Knee Arthroplasty Exchange for Periprosthetic Infection: A Preliminary Study.
    The Journal of arthroplasty, 2021, Volume: 36, Issue:12

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bone Cements

2021
Role of bacterial colonisation of vancomycin-gentamicin spacers in two-stage arthroplasty revision surgery: the usefulness of spacer sonication.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2022, Volume: 32, Issue:8

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Gentamicins; Humans; Prosthesis-Related Infec

2022
Polycatecholamine and gentamicin as modifiers for antibacterial and blood-biocompatible polyester vascular prostheses.
    Biomaterials advances, 2022, Volume: 133

    Topics: Animals; Anti-Bacterial Agents; Blood Vessel Prosthesis; Coated Materials, Biocompatible; Endothelia

2022
Microbiological profiles and antibiotic resistance of periprosthetic joint infection after hip replacement in patients with fracture or non-fracture: A comparative study.
    Journal of back and musculoskeletal rehabilitation, 2023, Volume: 36, Issue:1

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Cephalosporins; Clindamycin; Drug Resistance,

2023
Mechanical strength of antibiotic-loaded PMMA spacers in two-stage revision surgery.
    BMC musculoskeletal disorders, 2022, Oct-29, Volume: 23, Issue:1

    Topics: Anti-Bacterial Agents; Arthritis, Infectious; Bone Cements; Gentamicins; Humans; Polymethyl Methacry

2022
Does addition of gentamicin for antibiotic prophylaxis in total knee arthroplasty reduce the rate of periprosthetic joint infection?
    Archives of orthopaedic and trauma surgery, 2023, Volume: 143, Issue:8

    Topics: Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Cefazo

2023
Antibiotic release from PMMA spacers and PMMA beads measured with ELISA: Assessment of in vitro samples and drain fluid samples of patients.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2023, Volume: 41, Issue:8

    Topics: Anti-Bacterial Agents; Bone Cements; Drainage; Enzyme-Linked Immunosorbent Assay; Gentamicins; Human

2023
Treatment with gentamicin-impregnated collagen sponges in reducing infection of implantable cardiac devices: 10-year analysis with propensity score matching.
    Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 2023, Volume: 42, Issue:8

    Topics: Adult; Defibrillators, Implantable; Gentamicins; Humans; Pacemaker, Artificial; Propensity Score; Pr

2023
Electrophoretic deposition of gentamicin and chitosan into titanium nanotubes to target periprosthetic joint infection.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2023, Volume: 111, Issue:9

    Topics: Anti-Bacterial Agents; Chitosan; Gentamicins; Humans; Nanotubes; Prosthesis-Related Infections; Tita

2023
Periprosthetic joint infection:A South African perspective.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 2023, 06-05, Volume: 113, Issue:6

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Cross-Sectional Studies; Gentamicins; Humans;

2023
The use of antibiotic-loaded bone cement and systemic antibiotic prophylactic use in 2,971,357 primary total knee arthroplasties from 2010 to 2020: an international register-based observational study among countries in Africa, Europe, North America, and O
    Acta orthopaedica, 2023, 08-09, Volume: 94

    Topics: Africa; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Bone Cements; Cefazolin; Europe; Gen

2023
Enhanced antibiotic release from bone cement spacers utilizing dual antibiotic loading with elevated vancomycin concentrations in two-stage revision for periprosthetic joint infection.
    International orthopaedics, 2023, Volume: 47, Issue:11

    Topics: Anti-Bacterial Agents; Arthritis, Infectious; Bone Cements; Gentamicins; Humans; Polymethyl Methacry

2023
Vancomycin-Gentamicin Prefabricated Spacers in 2-Stage Revision Arthroplasty for Chronic Hip and Knee Periprosthetic Joint Infection: Insights Into Reimplantation Microbiology and Outcomes.
    The Journal of arthroplasty, 2020, Volume: 35, Issue:1

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements; Gentamicins; Humans; Prosthesis

2020
Staphylococcus aureus Prosthetic Joint Infection Is Prevented by a Fluorine- and Phosphorus-Doped Nanostructured Ti-6Al-4V Alloy Loaded With Gentamicin and Vancomycin.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2020, Volume: 38, Issue:3

    Topics: 3T3 Cells; Alloys; Animals; Anti-Bacterial Agents; Cell Differentiation; Cell Proliferation; Drug Ca

2020
Synergistic antibacterial effects of analgesics and antibiotics against Staphylococcus aureus.
    Diagnostic microbiology and infectious disease, 2020, Volume: 96, Issue:4

    Topics: Analgesics; Anti-Bacterial Agents; Drug Synergism; Gentamicins; Humans; Methicillin; Methicillin-Res

2020
Preclinical evaluation of efficacy and pharmacokinetics of gentamicin containing extracellular-matrix envelope.
    Pacing and clinical electrophysiology : PACE, 2020, Volume: 43, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Disease Models, Animal; Extracellular Matrix; Gentamicins; Pacemaker

2020
Modulating antibiotic release from reservoirs in 3D-printed orthopedic devices to treat periprosthetic joint infection.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2020, Volume: 38, Issue:10

    Topics: Anti-Bacterial Agents; Arthritis, Infectious; Drug Implants; Gentamicins; Humans; Printing, Three-Di

2020
Addressing prosthetic joint infections via gentamicin-eluting UHMWPE spacer.
    The bone & joint journal, 2020, Volume: 102-B, Issue:6_Supple_A

    Topics: Anti-Bacterial Agents; Bone Cements; Drug Carriers; Gentamicins; Humans; Knee Prosthesis; Polyethyle

2020
Acute kidney failure after intra-articular use of gentamicin sponge.
    The Netherlands journal of medicine, 2020, Volume: 78, Issue:2

    Topics: Acute Kidney Injury; Aged; Anti-Bacterial Agents; Gentamicins; Hip Prosthesis; Humans; Male; Prosthe

2020
The Efficacy of Breast Implant Irrigant Solutions: A Comparative Analysis Using an In Vitro Model.
    Plastic and reconstructive surgery, 2020, Volume: 146, Issue:2

    Topics: Anti-Infective Agents, Local; Bacitracin; Benzenesulfonates; Biofilms; Breast Implantation; Breast I

2020
The role of antibiotic-loaded bone cement in complicated knee arthroplasty: relevance of gentamicin allergy and benefit from revision surgery - a case control follow-up study and algorithmic approach.
    Journal of orthopaedic surgery and research, 2020, Aug-12, Volume: 15, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Bone Cements; Drug Hypersensitivity; F

2020
The Impact of Antibiotic-Loaded Bone Cement on Antibiotic Resistance in Periprosthetic Knee Infections.
    Clinics in orthopedic surgery, 2020, Volume: 12, Issue:3

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthroplasty, Replacement, Knee; Bone Cements; Drug R

2020
Material modifications enhancing the antibacterial properties of two biodegradable poly(3-hydroxybutyrate) implants.
    Biomedical materials (Bristol, England), 2020, 12-23, Volume: 16, Issue:1

    Topics: Absorbable Implants; Anti-Bacterial Agents; Bacterial Adhesion; Biocompatible Materials; Biofilms; C

2020
Bacteriophage-antibiotic combinations against ciprofloxacin/ceftriaxone-resistant Escherichia coli in vitro and in an experimental Galleria mellonella model.
    International journal of antimicrobial agents, 2020, Volume: 56, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Bacteriophages; Biofilms; Ceftriaxone; Ciprofloxacin; Combined Modal

2020
Current actual success rate of the two-stage exchange arthroplasty strategy in chronic hip and knee periprosthetic joint infection.
    The bone & joint journal, 2020, Volume: 102-B, Issue:12

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replac

2020
In Vitro Evaluation of Gentamicin or Vancomycin Containing Bone Graft Substitute in the Prevention of Orthopedic Implant-Related Infections.
    International journal of molecular sciences, 2020, Dec-04, Volume: 21, Issue:23

    Topics: Animals; Antibiotic Prophylaxis; Bacterial Adhesion; Biofilms; Bone Substitutes; Drug Resistance, Ba

2020
Single-stage revision of MRSA orthopedic device-related infection in sheep with an antibiotic-loaded hydrogel.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2021, Volume: 39, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Biofilms; Bone Cements; Drug Evaluation, Preclinical; Gentamicins; H

2021
The antimicrobial activity and biocompatibility of a controlled gentamicin-releasing single-layer sol-gel coating on hydroxyapatite-coated titanium.
    The bone & joint journal, 2021, Volume: 103-B, Issue:3

    Topics: Animals; Biofilms; Coated Materials, Biocompatible; Durapatite; Gentamicins; Materials Testing; Pros

2021
Acute Kidney Injury When Treating Periprosthetic Joint Infections After Total Knee Arthroplasties with Antibiotic-Loaded Spacers: Incidence, Risks, and Outcomes.
    The Journal of bone and joint surgery. American volume, 2021, 05-05, Volume: 103, Issue:9

    Topics: Acute Kidney Injury; Administration, Oral; Adult; Aged; Aged, 80 and over; Amphotericin B; Anti-Bact

2021
Treatment of severely open tibial fractures, non-unions, and fracture-related infections with a gentamicin-coated tibial nail-clinical outcomes including quality of life analysis and psychological ICD-10-based symptom rating.
    Journal of orthopaedic surgery and research, 2021, Apr-17, Volume: 16, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Bone Nails; Device Removal; Female; Fracture Fixation, Intramedu

2021
The use of antibiotic-loaded bone cement does not increase antibiotic resistance after primary total joint arthroplasty.
    Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2022, Volume: 30, Issue:9

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthritis, Infectious; Arthroplasty, Replacement, Kn

2022
Peri-Prosthetic Knee Infection Management: Spacers Loaded with Two or Three Antibiotic Agents.
    Surgical infections, 2017, Volume: 18, Issue:5

    Topics: Adult; Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Bone Cements; Clindamycin; Fema

2017
Dalbavancin treatment of prosthetic knee infection due to oxacillin-resistant Staphylococcus epidermidis.
    Enfermedades infecciosas y microbiologia clinica (English ed.), 2018, Volume: 36, Issue:2

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Device Removal; Drug Resistance, Multiple, B

2018
Drug-induced immune hemolytic anemia associated with anti-vancomycin complicated by a paraben antibody.
    Transfusion, 2018, Volume: 58, Issue:1

    Topics: Anemia, Hemolytic; Anti-Bacterial Agents; Antibodies; Antibody Specificity; Arthroplasty, Replacemen

2018
The influence of antibiotic-loaded cement spacers on the risk of reinfection after septic two-stage hip revision surgery.
    Infection, 2017, Volume: 45, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements;

2017
In vitro anti-biofilm activity of a biphasic gentamicin-loaded calcium sulfate/hydroxyapatite bone graft substitute.
    Colloids and surfaces. B, Biointerfaces, 2018, Jan-01, Volume: 161

    Topics: Anti-Bacterial Agents; Bacterial Adhesion; Biofilms; Bone Substitutes; Calcium Sulfate; Drug Liberat

2018
Systemic Absorption of Antibiotics From Antibiotic-Loaded Cement Spacers for the Treatment of Periprosthetic Joint Infection.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:3

    Topics: Absorption, Physiological; Aged; Anti-Bacterial Agents; Arthritis, Infectious; Arthroplasty, Replace

2018
Use of modular megaprosthesis in managing chronic end-stage periprosthetic hip and knee infections: Is there an increase in relapse rate?
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2018, Volume: 28, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; A

2018
Staged Revision With Antibiotic Spacers for Shoulder Prosthetic Joint Infections Yields High Infection Control.
    Clinical orthopaedics and related research, 2018, Volume: 476, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Shoulder; Bone Cem

2018
Nephrotoxicity After the Treatment of Periprosthetic Joint Infection With Antibiotic-Loaded Cement Spacers.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:7

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthritis, Infectious; Arthropl

2018
Gentamicin may have no effect on mortality of staphylococcal prosthetic valve endocarditis.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2018, Volume: 24, Issue:7

    Topics: Aged; Anti-Bacterial Agents; Cloxacillin; Endocarditis, Bacterial; Female; Gentamicins; Heart Failur

2018
Antimicrobial and Antifouling Polymeric Agents for Surface Functionalization of Medical Implants.
    Biomacromolecules, 2018, 07-09, Volume: 19, Issue:7

    Topics: Animals; Anti-Infective Agents; Biofilms; Coated Materials, Biocompatible; Escherichia coli; Female;

2018
Antibiotic release and antibacterial efficacy in cement spacers and cement beads impregnated with different techniques: In vitro study.
    Eklem hastaliklari ve cerrahisi = Joint diseases & related surgery, 2018, Volume: 29, Issue:2

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements; Drug Delivery Systems; Gentamic

2018
Antibiotic release from F-doped nanotubular oxide layer on TI6AL4V alloy to decrease bacterial viability.
    Journal of materials science. Materials in medicine, 2018, Jul-20, Volume: 29, Issue:8

    Topics: Alloys; Anti-Bacterial Agents; Arthroplasty; Bacterial Adhesion; Biocompatible Materials; Chromatogr

2018
Use of gentamicin-impregnated beads or sponges in the treatment of early acute periprosthetic joint infection: a propensity score analysis.
    The Journal of antimicrobial chemotherapy, 2018, 12-01, Volume: 73, Issue:12

    Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthritis; Drug Delivery Sy

2018
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2018, 09-17, Volume: 190, Issue:37

    Topics: Aged, 80 and over; Animals; Anti-Bacterial Agents; Brucella; Brucellosis; Canada; Endocarditis; Gent

2018
Antibiotics release from cement spacers used for two-stage treatment of implant-associated infections after total joint arthroplasty.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2019, Volume: 107, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replac

2019
LbL-assembled gentamicin delivery system for PMMA bone cements to prolong antimicrobial activity.
    PloS one, 2018, Volume: 13, Issue:12

    Topics: Anti-Infective Agents; Bone Cements; Cell Line; Cell Survival; Compressive Strength; Drug Delivery S

2018
Minimum 5 years' follow-up after gentamicin- and clindamycin-loaded PMMA cement in total joint arthroplasty.
    Journal of medical microbiology, 2019, Volume: 68, Issue:3

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements; Clinda

2019
Two-Stage Exchange Protocol for Periprosthetic Joint Infection Following Total Knee Arthroplasty in 245 Knees without Prior Treatment for Infection.
    The Journal of bone and joint surgery. American volume, 2019, Feb-06, Volume: 101, Issue:3

    Topics: Adult; Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Bone Resorption; Clinical Proto

2019
Antibiotic elution and compressive strength of gentamicin/vancomycin loaded bone cements are considerably influenced by immersion fluid volume.
    Journal of materials science. Materials in medicine, 2019, Feb-14, Volume: 30, Issue:2

    Topics: Anti-Bacterial Agents; Bone Cements; Compressive Strength; Drug Implants; Drug Liberation; Gentamici

2019
Effect of trabecular metal on the elution of gentamicin from Palacos cement.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2019, Volume: 37, Issue:5

    Topics: Anti-Bacterial Agents; Bone Cements; Gentamicins; Humans; Joint Prosthesis; Polymethyl Methacrylate;

2019
Audiometric threshold shifts after total knee arthroplasty by using gentamicin-loaded\ bone cement
    Turkish journal of medical sciences, 2019, 04-18, Volume: 49, Issue:2

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Audiometry, Pure-To

2019
Chitosan/montmorillonite composite nanospheres for sustained antibiotic delivery at post-implantation bone infection treatment.
    Biomedical materials (Bristol, England), 2019, 05-17, Volume: 14, Issue:4

    Topics: 3T3 Cells; Animals; Anti-Bacterial Agents; Bentonite; Bone and Bones; Bone Transplantation; Chitosan

2019
Evaluation of collagen/hydroxyapatite electrospun layers loaded with vancomycin, gentamicin and their combination: Comparison of release kinetics, antimicrobial activity and cytocompatibility.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2019, Volume: 140

    Topics: Anti-Bacterial Agents; Bone Cements; Cell Line; Collagen; Drug Synergism; Durapatite; Enterococcus f

2019
[Efficacy evaluation of one-stage revision combined with intra-articular injection of antifungal agents in the treatment of chronic periprosthetic fungal infection].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2019, May-01, Volume: 57, Issue:5

    Topics: Aged; Anti-Bacterial Agents; Antifungal Agents; Arthroplasty, Replacement; Chronic Disease; Combined

2019
Bacterial colonization and resistance patterns in 133 patients undergoing a primary hip- or knee replacement in Southern Sweden.
    Acta orthopaedica, 2013, Volume: 84, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthroplasty, Replace

2013
[Microbial and pharmacological characteristics of VancogenX].
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 2013, Volume: 80, Issue:1

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bacteria; Biofilms; Bone Cements; Drug Implan

2013
Characterisation of in vivo release of gentamicin from polymethyl methacrylate cement using a novel method.
    International orthopaedics, 2013, Volume: 37, Issue:10

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Biocompatible Materials; Biomarkers; Bone Cem

2013
Proceedings of scientific instructional conference on local antibiotic therapy on prevention and treatment of infections in orthopaedics and traumatology.
    Polish orthopedics and traumatology, 2013, Jun-13, Volume: 78

    Topics: Administration, Metronomic; Anti-Bacterial Agents; Anti-Infective Agents, Local; Drug Implants; Gent

2013
Industrially prefabricated cement spacers: do vancomycin- and gentamicin-impregnated spacers offer any advantage?
    Clinical orthopaedics and related research, 2014, Volume: 472, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bon

2014
Good results in postoperative and hematogenous deep infections of 89 stable total hip and knee replacements with retention of prosthesis and local antibiotics.
    Acta orthopaedica, 2013, Volume: 84, Issue:6

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replac

2013
The cement prosthesis-like spacer: an intermediate halt on the road to healing.
    TheScientificWorldJournal, 2013, Volume: 2013

    Topics: Arthritis, Infectious; Arthroplasty, Replacement, Knee; Bone Cements; Debridement; Enterococcus; Gen

2013
Two-stage revision for infected total knee arthroplasty: our experience with interval prosthesis.
    European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2014, Volume: 24, Issue:7

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Bone Cements; Femal

2014
Intraoperative intra-articular injection of gentamicin: will it decrease the risk of infection in total shoulder arthroplasty?
    Journal of shoulder and elbow surgery, 2014, Volume: 23, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement; Female; Gentamicin

2014
Antimicrobial activity of gentamicin and vancomycin combination in joint fluids after antibiotic-loaded cement spacer implantation in two-stage revision surgery.
    Journal of chemotherapy (Florence, Italy), 2015, Volume: 27, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Bacteriological Techniques; Bone Cements; Drug Resistance, Multi

2015
Evidence of MRSE on a gentamicin and vancomycin impregnated polymethyl-methacrylate (PMMA) bone cement spacer after two-stage exchange arthroplasty due to periprosthetic joint infection of the knee.
    BMC infectious diseases, 2014, Mar-18, Volume: 14

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Bone Cements; Drug Resistance, Multiple, Bac

2014
Antibiotic susceptibility in gram-positive chronic joint arthroplasty infections: increased aminoglycoside resistance rate in patients with prior aminoglycoside-impregnated cement spacer use.
    The Journal of arthroplasty, 2014, Volume: 29, Issue:8

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replac

2014
[Evaluation of the importance of a ready-made, gentamicin-impregnated spacer in relation to bacteriological findings in patients with periprosthetic joint infections].
    Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne, 2014, Volume: 63, Issue:2

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bacteria; Fe

2014
Gentamicin for prevention of intraoperative mesh contamination: demonstration of high bactericide effect (in vitro) and low systemic bioavailability (in vivo).
    Hernia : the journal of hernias and abdominal wall surgery, 2014, Volume: 18, Issue:5

    Topics: Administration, Topical; Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug Monitoring; Equipment

2014
Local gentamicin delivery from resorbable viscous hydrogels is therapeutically effective.
    Clinical orthopaedics and related research, 2015, Volume: 473, Issue:1

    Topics: Absorbable Implants; Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Blood Urea Nitrog

2015
CORR Insights®: Local gentamicin delivery from resorbable viscous hydrogels is therapeutically effective.
    Clinical orthopaedics and related research, 2015, Volume: 473, Issue:1

    Topics: Absorbable Implants; Animals; Anti-Bacterial Agents; Anti-Infective Agents, Local; Bone Wires; Drug

2015
Case report of a successfully treated gentamicin and ciprofloxacin resistant Serratia marcescens prosthetic joint infection.
    Annals of the Royal College of Surgeons of England, 2014, Volume: 96, Issue:8

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Ciprofloxacin; Gentamicins; Humans; Male; Mid

2014
Coating with a novel gentamicinpalmitate formulation prevents implant-associated osteomyelitis induced by methicillin-susceptible Staphylococcus aureus in a rat model.
    International orthopaedics, 2015, Volume: 39, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Coated Materials, Biocompatible; Disease Mod

2015
Activity of bone cement loaded with daptomycin alone or in combination with gentamicin or PEG600 against Staphylococcus epidermidis biofilms.
    Injury, 2015, Volume: 46, Issue:2

    Topics: Anti-Bacterial Agents; Bacterial Adhesion; Biofilms; Bone and Bones; Bone Cements; Daptomycin; Genta

2015
Antibiotic-loaded cement spacer for treatment of Klebsiella infected total hip and knee arthroplasty.
    Vojnosanitetski pregled, 2014, Volume: 71, Issue:10

    Topics: Algorithms; Anti-Bacterial Agents; Bone Cements; Clindamycin; Drug Combinations; Drug Resistance, Mu

2014
A biodegradable gentamicin-hydroxyapatite-coating for infection prophylaxis in cementless hip prostheses.
    European cells & materials, 2015, Jan-02, Volume: 29

    Topics: Animals; Anti-Bacterial Agents; Bone Cements; Bone Nails; Coated Materials, Biocompatible; Dogs; Dru

2015
Antimicrobial Release From Prefabricated Spacers Is Variable and the Dose Is Low.
    Clinical orthopaedics and related research, 2015, Volume: 473, Issue:7

    Topics: Anti-Bacterial Agents; Bone Cements; Drug Carriers; Gentamicins; Prosthesis Design; Prosthesis-Relat

2015
[Propionibacterium granulosum bare-metal stent infection after drug-eluting balloon].
    Journal des maladies vasculaires, 2015, Volume: 40, Issue:4

    Topics: Aged, 80 and over; Alloys; Amoxicillin; Angioplasty, Balloon, Coronary; Anti-Bacterial Agents; Arter

2015
The cement spacer with multiple indentations: increasing antibiotic elution using a cement spacer 'teabag'.
    The bone & joint journal, 2015, Volume: 97-B, Issue:11

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement; Bone Cements; Chromatography, High Pressure Liquid

2015
The use of calcium carbonate beads containing gentamicin in the second stage septic revision of total knee arthroplasty reduces reinfection rate.
    The Knee, 2016, Volume: 23, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Calcium Carbonate; Drug Carriers; Fema

2016
2-stage revision of 120 deep infected hip and knee prostheses using gentamicin-PMMA beads.
    Acta orthopaedica, 2016, Volume: 87, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthroplasty,

2016
In vivo quantification of gentamicin released from an implant coating.
    Journal of biomaterials applications, 2016, Volume: 31, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Bacterial Infections; Bone Wires; Coated Materials, Biocompatible; D

2016
Systemic antibiotic therapy does not significantly improve outcome in a rat model of implant-associated osteomyelitis induced by Methicillin susceptible Staphylococcus aureus.
    Archives of orthopaedic and trauma surgery, 2016, Volume: 136, Issue:4

    Topics: Animals; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Gentamicins; Injections, Intraperit

2016
Bio-absorbable antibiotic impregnated beads for the treatment of prosthetic vascular graft infections.
    Vascular, 2016, Volume: 24, Issue:6

    Topics: Absorbable Implants; Academic Medical Centers; Aged; Anti-Bacterial Agents; Blood Vessel Prosthesis;

2016
Antibiotic-Loaded Spacer for Two-Stage Revision of Infected Total Knee Arthroplasty.
    The journal of knee surgery, 2017, Volume: 30, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthritis; Arthroplasty, Replacement, Knee; C

2017
Rare case of simultaneous enterococcal endocarditis and prosthetic joint infection.
    BMJ case reports, 2016, May-20, Volume: 2016

    Topics: Echocardiography, Transesophageal; Endocarditis, Bacterial; Enterococcus faecalis; Gentamicins; Gram

2016
In vitro activity of gentamicin as an adjunct to penicillin against biofilm group B Streptococcus.
    The Journal of antimicrobial chemotherapy, 2017, Volume: 72, Issue:2

    Topics: Anti-Bacterial Agents; Biofilms; Colony Count, Microbial; Drug Synergism; Drug Therapy, Combination;

2017
Superficial Vancomycin Coating of Bone Cement in Orthopedic Revision Surgery: A Safe Technique to Enhance Local Antibiotic Concentrations.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:5

    Topics: Administration, Topical; Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthroplasty,

2017
Enhanced Antimicrobial Effects of Decellularized Extracellular Matrix (CorMatrix) with Added Vancomycin and Gentamicin for Device Implant Protection.
    Pacing and clinical electrophysiology : PACE, 2017, Volume: 40, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Cell-Free System; Combined Modality Therapy; Defibrillators, Implant

2017
Bone penetration of intravenous flucloxacillin and gentamicin as antibiotic prophylaxis during total hip and knee arthroplasty.
    The bone & joint journal, 2017, Volume: 99-B, Issue:3

    Topics: Acetabulum; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthropla

2017
Cement spacer loaded with antibiotics for infected implants of the hip joint.
    The Journal of arthroplasty, 2009, Volume: 24, Issue:1

    Topics: Adult; Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements; Dose-Response Rela

2009
In vitro release of antibiotics from commercial PMMA beads and articulating hip spacers.
    The Journal of arthroplasty, 2008, Volume: 23, Issue:8

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bacterial Infections; Bone Cements; Dose-Resp

2008
In vivo pharmacokinetics of a gentamicin-loaded collagen sponge in acute periprosthetic infection: serum values in 19 patients.
    Acta orthopaedica, 2008, Volume: 79, Issue:5

    Topics: Acute Disease; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Arthr

2008
[Propionibacterium acnes endocarditis on an aortic prosthesis in a patient carrying a pacemaker].
    Medecine et maladies infectieuses, 2008, Volume: 38, Issue:12

    Topics: Abscess; Aged; Amoxicillin; Anti-Bacterial Agents; Aortic Valve; Bacteremia; Combined Modality Thera

2008
In vitro testing of chitosan in gentamicin-loaded bone cement: no antimicrobial effect and reduced mechanical performance.
    Acta orthopaedica, 2008, Volume: 79, Issue:6

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement; Bacterial Adhesion; Biofilms; Bone Cements; Chitos

2008
Efficacy of combination of N-acetylcysteine, gentamicin, and amphotericin B for prevention of microbial colonization of ventricular assist devices.
    Infection control and hospital epidemiology, 2009, Volume: 30, Issue:2

    Topics: Acetylcysteine; Amphotericin B; Animals; Anti-Bacterial Agents; Coated Materials, Biocompatible; Dis

2009
Is prolonged systemic antibiotic treatment essential in two-stage revision hip replacement for chronic Gram-positive infection?
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Debridement;

2009
[Conservative treatment of a hip prosthesis infection due to methicillin-resistant Staphylococcus aureus using prolonged antibiotic therapy based on linezolid followed by daptomycin].
    Medecine et maladies infectieuses, 2008, Volume: 38 Spec No 2

    Topics: Acetamides; Aged, 80 and over; Anesthesia; Anti-Bacterial Agents; Bacteremia; Bone Marrow Diseases;

2008
[Treatment of mitral MRSA endocarditis using daptomycin].
    Medecine et maladies infectieuses, 2008, Volume: 38 Spec No 2

    Topics: Aged; Anti-Bacterial Agents; Bacteremia; Combined Modality Therapy; Daptomycin; Device Removal; Drug

2008
Reduction of postoperative spinal implant infection using gentamicin microspheres.
    Spine, 2009, Mar-01, Volume: 34, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Biocompatible Materials; Bone Nails; Delayed-Action Preparations; Dr

2009
Liquid gentamicin in bone cement spacers: in vivo antibiotic release and systemic safety in two-stage revision of infected hip arthroplasty.
    The Journal of trauma, 2009, Volume: 66, Issue:3

    Topics: Aged; Biological Availability; Drug Therapy, Combination; Female; Gentamicins; Hip Prosthesis; Human

2009
Elution of gentamicin and vancomycin from polymethylmethacrylate beads and hip spacers in vivo.
    Acta orthopaedica, 2009, Volume: 80, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements;

2009
Elution of gentamicin and vancomycin from polymethylmethacrylate beads and hip spacers in vivo.
    Acta orthopaedica, 2009, Volume: 80, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements;

2009
Elution of gentamicin and vancomycin from polymethylmethacrylate beads and hip spacers in vivo.
    Acta orthopaedica, 2009, Volume: 80, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements;

2009
Elution of gentamicin and vancomycin from polymethylmethacrylate beads and hip spacers in vivo.
    Acta orthopaedica, 2009, Volume: 80, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements;

2009
The microbiology of the infected knee arthroplasty.
    International orthopaedics, 2010, Volume: 34, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Coagulase; D

2010
The "glove" technique: a modified method for femoral fixation of antibiotic-loaded hip spacers.
    Acta orthopaedica, 2009, Volume: 80, Issue:3

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements; Drug Delivery Systems; Gentamic

2009
Compression strength and porosity of single-antibiotic cement vacuum-mixed with vancomycin.
    The Journal of arthroplasty, 2010, Volume: 25, Issue:6

    Topics: Arthroplasty, Replacement; Bone Cements; Compressive Strength; Gentamicins; Humans; Methylmethacryla

2010
In situ treatment of an infected intrathecal baclofen pump implant with gentamicin-impregnated collagen fleece.
    Journal of neurosurgery, 2010, Volume: 112, Issue:6

    Topics: Anti-Bacterial Agents; Baclofen; Collagen; Debridement; Drug Implants; Gentamicins; Humans; Infusion

2010
Vascular prostheses with covalently bound gentamicin and amikacin reveal superior antibacterial properties than silver-impregnated ones--an in vitro study.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2009, Volume: 38, Issue:6

    Topics: Amikacin; Anti-Bacterial Agents; Bacteria; Biofilms; Blood Vessel Prosthesis; Cell Proliferation; Ce

2009
Knee arthodesis using a modular customized intramedullary nail.
    Orthopaedics & traumatology, surgery & research : OTSR, 2009, Volume: 95, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthrodesis; Bacterial Infections; Drug Impla

2009
Concepts for increasing gentamicin release from handmade bone cement beads.
    Acta orthopaedica, 2009, Volume: 80, Issue:5

    Topics: Biofilms; Bone Cements; Drug Carriers; Drug Compounding; Drug Implants; Gentamicins; Humans; Materia

2009
A biodegradable antibiotic delivery system based on poly-(trimethylene carbonate) for the treatment of osteomyelitis.
    Acta orthopaedica, 2009, Volume: 80, Issue:5

    Topics: Absorbable Implants; Anti-Bacterial Agents; Biofilms; Bone Cements; Dioxanes; Drug Carriers; Gentami

2009
High systemic gentamicin levels and ototoxicity after implantation of gentamicin beads in a 70-year-old man--a case report.
    Acta orthopaedica, 2009, Volume: 80, Issue:6

    Topics: Aged; Anti-Bacterial Agents; Arthritis, Infectious; Arthroplasty, Replacement, Hip; Drug Implants; G

2009
Gentamycin delivered from a PDLLA coating of metallic implants: In vivo and in vitro characterisation for local prophylaxis of implant-related osteomyelitis.
    Injury, 2010, Volume: 41, Issue:10

    Topics: Animals; Anti-Bacterial Agents; Coated Materials, Biocompatible; Delayed-Action Preparations; Drug A

2010
In vitro assessment of antimicrobial properties of rifampin-coated Titan(®) Coloplast penile implants and comparison with Inhibizone(®).
    The journal of sexual medicine, 2010, Volume: 7, Issue:10

    Topics: Anti-Bacterial Agents; Escherichia coli; Escherichia coli Infections; Gentamicins; Humans; Male; Mic

2010
Management of septic complications following modular endoprosthetic reconstruction of the proximal femur.
    International orthopaedics, 2011, Volume: 35, Issue:10

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements; Bone N

2011
Infection rates of rifampin/gentamicin-coated Titan Coloplast penile implants. Comparison with Inhibizone-impregnated AMS penile implants.
    The journal of sexual medicine, 2011, Volume: 8, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Case-Control Studies; Coated Materials, Bioco

2011
Dialysis: Are prophylactic gentamicin catheter locks safe?
    Nature reviews. Nephrology, 2011, Volume: 7, Issue:1

    Topics: Anti-Bacterial Agents; Catheters, Indwelling; Drug Resistance, Bacterial; Gentamicins; Humans; Kidne

2011
Gentamicin release from commercially-available gentamicin-loaded PMMA bone cements in a prosthesis-related interfacial gap model and their antibacterial efficacy.
    BMC musculoskeletal disorders, 2010, Nov-10, Volume: 11

    Topics: Animals; Bone Cements; Gentamicins; Methylmethacrylates; Models, Biological; Polymethyl Methacrylate

2010
Ica-expression and gentamicin susceptibility of Staphylococcus epidermidis biofilm on orthopedic implant biomaterials.
    Journal of biomedical materials research. Part A, 2011, Volume: 96, Issue:2

    Topics: Arthroplasty; Bacterial Proteins; Biocompatible Materials; Biofilms; Gene Expression Regulation, Bac

2011
Late hip arthroplasty infection caused by Listeria monocytogenes in a non-immunocompromised patient.
    Surgical infections, 2011, Volume: 12, Issue:2

    Topics: Aged; Ampicillin; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Gentamicins; Humans; Lister

2011
Antibacterial efficacy of a new gentamicin-coating for cementless prostheses compared to gentamicin-loaded bone cement.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2011, Volume: 29, Issue:11

    Topics: Alloys; Anti-Bacterial Agents; Bone Cements; Coated Materials, Biocompatible; Gentamicins; Hip Prost

2011
An articulating antibiotic spacer controls infection and improves pain and function in a degenerative septic hip.
    Clinical orthopaedics and related research, 2011, Volume: 469, Issue:11

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthritis, Infectious; Arthroplasty, Replacement, Hi

2011
Gait analysis in patients with a preformed articulated knee spacer.
    The Knee, 2012, Volume: 19, Issue:4

    Topics: Anti-Bacterial Agents; Bone Cements; Female; Gait; Gentamicins; Humans; Knee Joint; Knee Prosthesis;

2012
Antimicrobial activity of gentamicin palmitate against high concentrations of Staphylococcus aureus.
    Journal of materials science. Materials in medicine, 2011, Volume: 22, Issue:6

    Topics: Anti-Bacterial Agents; Bone Cements; Coated Materials, Biocompatible; Colony Count, Microbial; Genta

2011
Use of gentamicin collagen sponges for the treatment of periprosthetic breast implant infection.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2011, Volume: 64, Issue:12

    Topics: Adult; Anti-Bacterial Agents; Breast Implants; Ciprofloxacin; Clindamycin; Collagen; Combined Modali

2011
Gentamicin improves the activities of daptomycin and vancomycin against Enterococcus faecalis in vitro and in an experimental foreign-body infection model.
    Antimicrobial agents and chemotherapy, 2011, Volume: 55, Issue:10

    Topics: Animals; Anti-Bacterial Agents; Daptomycin; Drug Therapy, Combination; Enterococcus faecalis; Gentam

2011
The modified static spacers using antibiotic-impregnated cement rod in two-stage revision for infected total knee arthroplasty.
    Clinics in orthopedic surgery, 2011, Volume: 3, Issue:3

    Topics: Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Bone Cements; Bone Nails; Device Remov

2011
Magnetic Drug Targeting as New Therapeutic Option for the Treatment of Biomaterial Infections.
    Journal of biomaterials science. Polymer edition, 2012, Volume: 23, Issue:18

    Topics: Anti-Bacterial Agents; Biocompatible Materials; Dose-Response Relationship, Drug; Drug Carriers; Dru

2012
Re: use of gentamicin collagen sponges for the treatment of periprosthetic breast implant infection.
    Journal of plastic, reconstructive & aesthetic surgery : JPRAS, 2012, Volume: 65, Issue:5

    Topics: Anti-Bacterial Agents; Breast Implants; Female; Gentamicins; Humans; Prosthesis-Related Infections

2012
[Native valve postoperative Klebsiella pneumoniae endocarditis].
    Medecine et maladies infectieuses, 2012, Volume: 42, Issue:2

    Topics: Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Bacteremia; Ceftriaxone; Cross Infecti

2012
Vacuum-mixing significantly changes antibiotic elution characteristics of commercially available antibiotic-impregnated bone cements.
    The Journal of bone and joint surgery. American volume, 2011, Nov-16, Volume: 93, Issue:22

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement; Bone Cements; Drug Delivery Systems; Evidence-Base

2011
New PMMA-based composites for preparing spacer devices in prosthetic infections.
    Journal of materials science. Materials in medicine, 2012, Volume: 23, Issue:5

    Topics: Animals; Anti-Bacterial Agents; Barium Compounds; Biocompatible Materials; Cells, Cultured; Drug Com

2012
Preparation of gentamicin-loaded electrospun coating on titanium implants and a study of their properties in vitro.
    Archives of orthopaedic and trauma surgery, 2012, Volume: 132, Issue:6

    Topics: Analysis of Variance; Anti-Bacterial Agents; Bacterial Adhesion; Coated Materials, Biocompatible; Ge

2012
Does a prefabricated gentamicin-impregnated, load-bearing spacer control periprosthetic hip infection?
    Clinical orthopaedics and related research, 2012, Volume: 470, Issue:10

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Drug Delivery Systems; Female; Gentamicins; Hip Pros

2012
Kytococcus schroeteri prosthetic valve endocarditis.
    BMJ case reports, 2010, Sep-29, Volume: 2010

    Topics: Actinomycetales; Actinomycetales Infections; Anti-Bacterial Agents; Aortic Valve; Drug Therapy, Comb

2010
Electrochemically deposited gentamicin-loaded calcium phosphate coatings for bone tissue integration.
    The International journal of artificial organs, 2012, Volume: 35, Issue:10

    Topics: Alloys; Anti-Bacterial Agents; Bacterial Adhesion; Calcium Phosphates; Coated Materials, Biocompatib

2012
Radiological evaluation of acetabular erosion after antibiotic-impregnated polymethylmethacrylate spacer (Spacer-G).
    The Journal of arthroplasty, 2013, Volume: 28, Issue:6

    Topics: Acetabulum; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Female; Gentamicins; Hip Prosthes

2013
Ceramic gentamicin beads in vascular graft infection--a cautionary note.
    Vascular and endovascular surgery, 2013, Volume: 47, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Aortic Aneurysm, Abdominal; Blood Vessel Prosthesis; Blood Vessel Prost

2013
[Two-stage revision of infected total knee arthroplasty using antibiotic-impregnated articulating cement spacer].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2012, Volume: 26, Issue:10

    Topics: Adult; Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Bone Cements; Female; Gentamici

2012
Cerebrospinal fluid shunt infection due to Gemella haemolysans.
    Journal of neurosurgery. Pediatrics, 2013, Volume: 11, Issue:2

    Topics: Adolescent; Anti-Bacterial Agents; Causality; Ceftazidime; Central Nervous System Infections; Dandy-

2013
Evaluating effectiveness of antibiotic polymethylmethacrylate beads in achieving wound sterilization and graft preservation in patients with early and late vascular graft infections.
    Surgery, 2013, Volume: 153, Issue:5

    Topics: Administration, Topical; Aged; Aged, 80 and over; Amputation, Surgical; Anti-Bacterial Agents; Antis

2013
Successful clinical use of daptomycin-impregnated bone cement in two-stage revision hip surgery for prosthetic joint infection.
    The Annals of pharmacotherapy, 2013, Volume: 47, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Bone Cements; Daptomycin; Drug Resistance, Multiple, Bacterial; Drug Th

2013
Haemophilus influenza infection complicating a total knee arthroplasty.
    Clinical orthopaedics and related research, 2002, Issue:402

    Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Arthroplasty, Replacement, Knee; Ciprofloxacin;

2002
Acute renal failure after local gentamicin treatment in an infected total knee arthroplasty.
    The Journal of arthroplasty, 2002, Volume: 17, Issue:7

    Topics: Acute Kidney Injury; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee

2002
Systemic inflammatory response induced by dacron graft and modulation by antimicrobial agents: experimental study.
    The Journal of surgical research, 2002, Volume: 107, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Antibiotics, Antitubercular; Bacterial Physiological Phenomena; Cefa

2002
Antibiotic bone cement for the treatment of Pseudomonas aeruginosa in joint arthroplasty: comparison of tobramycin and gentamicin-loaded cements.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2003, Feb-15, Volume: 64, Issue:2

    Topics: Anti-Bacterial Agents; Bone Cements; Gentamicins; Humans; In Vitro Techniques; Joint Prosthesis; Mic

2003
Mechanical characteristics of antibiotic-laden bone cement.
    Acta orthopaedica Scandinavica, 2002, Volume: 73, Issue:6

    Topics: Anti-Bacterial Agents; Bone Cements; Drug Interactions; Drug Therapy, Combination; Floxacillin; Gent

2002
Treatment outcome of two-stage revision total hip arthroplasty for infected hip arthroplasty using antibiotic-impregnated cement spacer.
    Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association, 2003, Volume: 8, Issue:1

    Topics: Aged; Aminoglycosides; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements; Dibekaci

2003
Residual gentamicin-release from antibiotic-loaded polymethylmethacrylate beads after 5 years of implantation.
    Biomaterials, 2003, Volume: 24, Issue:10

    Topics: Aged; Anti-Bacterial Agents; Biocompatible Materials; Drug Implants; Drug Resistance, Bacterial; Gen

2003
Electromagnetic augmentation of antibiotic efficacy in infection of orthopaedic implants.
    The Journal of bone and joint surgery. British volume, 2003, Volume: 85, Issue:4

    Topics: Analysis of Variance; Anti-Bacterial Agents; Biofilms; Colony Count, Microbial; Electromagnetic Fiel

2003
Unusual morphology in orthokeratology contact lens-related cornea ulcer.
    Eye & contact lens, 2003, Volume: 29, Issue:3

    Topics: Adolescent; Cefazolin; Contact Lenses; Corneal Ulcer; Drug Therapy, Combination; Eye Infections, Bac

2003
Pseudomonas keratitis associated with continuous wear silicone-hydrogel soft contact lens: a case report.
    Eye & contact lens, 2003, Volume: 29, Issue:4

    Topics: Adult; Cefazolin; Ciprofloxacin; Contact Lenses, Extended-Wear; Corneal Ulcer; Drug Therapy, Combina

2003
The combination of systemic antibiotics and antibiotics impregnated cement in primary total knee arthroplasty in patients of rheumatoid arthritis--evaluation of 60 knees.
    Journal of the Chinese Medical Association : JCMA, 2003, Volume: 66, Issue:9

    Topics: Adult; Aged; Anti-Bacterial Agents; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Bone Cem

2003
Long-term bactericidal properties of a gentamicin-coated antimicrobial external fixation pin sleeve.
    The Journal of bone and joint surgery. American volume, 2003, Volume: 85-A Suppl 4

    Topics: Anti-Bacterial Agents; Bone Nails; Coated Materials, Biocompatible; Delayed-Action Preparations; Ext

2003
A covalent method of gentamicin bonding to silica supports.
    Journal of biomaterials applications, 2004, Volume: 18, Issue:4

    Topics: Adsorption; Animals; Anti-Bacterial Agents; Cell Division; Cell Survival; Coated Materials, Biocompa

2004
[A cannulated articulating spacer--a functional implant for treatment of infected hip joint prostheses].
    Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca, 2004, Volume: 71, Issue:2

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements; Female; Gentamicins; Hip Joint;

2004
Response to: release of gentamicin and vancomycin from temporary human hip spacers in two-stage revision of infected arthroplasty.
    The Journal of antimicrobial chemotherapy, 2004, Volume: 54, Issue:2

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Gentamicins; Hip Prosthesis; Humans; Polymeth

2004
Pulmonary homograft endocarditis after Ross procedure.
    The Annals of thoracic surgery, 2004, Volume: 78, Issue:2

    Topics: Adult; Ampicillin; Aortic Valve; Bioprosthesis; Combined Modality Therapy; Drug Therapy, Combination

2004
[Antibiotic-loaded bone cements: from laboratory studies clinical evaluation].
    Bulletin de l'Academie nationale de medecine, 2004, Volume: 188, Issue:6

    Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthroplasty, Replacement, Hip; Biocompatible Materia

2004
Infective endocarditis due to Abiotrophia defectiva: a report of two cases.
    The Journal of heart valve disease, 2005, Volume: 14, Issue:1

    Topics: Adult; Anti-Bacterial Agents; Aortic Valve; Ceftriaxone; Drug Therapy, Combination; Endocarditis, Ba

2005
Treatment of infected retained implants.
    The Journal of bone and joint surgery. British volume, 2005, Volume: 87, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Ankle Joint; Anti-Bacterial Agents; Bacterial Infections; Cloxacilli

2005
Bacterial survival in the interfacial gap in gentamicin-loaded acrylic bone cements.
    The Journal of bone and joint surgery. British volume, 2005, Volume: 87, Issue:2

    Topics: Anti-Bacterial Agents; Bacteria; Biofilms; Bone Cements; Colony Count, Microbial; Dose-Response Rela

2005
Antibacterial activity of gentamicin-bonded gelatin-sealed polyethylene terephthalate vascular prostheses.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2005, Volume: 29, Issue:4

    Topics: Anti-Bacterial Agents; Blood Vessel Prosthesis; Escherichia coli; Gelatin; Gentamicins; Humans; Micr

2005
Treatment of biofilm infections on implants with low-frequency ultrasound and antibiotics.
    American journal of infection control, 2005, Volume: 33, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Biofilms; Cervical Vertebrae; Disease Models, Animal; Escherichia co

2005
Toxic serum gentamicin levels after the use of gentamicin-loaded sponges in infected total hip arthroplasty.
    Acta orthopaedica, 2005, Volume: 76, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Creatinine; Female; Gentamicins; Humans

2005
Pseudomonas aeruginosa biofilm formation and slime excretion on antibiotic-loaded bone cement.
    Acta orthopaedica, 2005, Volume: 76, Issue:1

    Topics: Anti-Bacterial Agents; Bacterial Adhesion; Biofilms; Bone Cements; Gentamicins; Humans; Prosthesis-R

2005
Pre-formed articulating knee spacer in two-stage revision for the infected total knee arthroplasty.
    International orthopaedics, 2005, Volume: 29, Issue:5

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Bone Cements; Drug

2005
Treatment of prosthetic valve infective endocarditis due to multi-resistant Gram-positive bacteria with linezolid.
    The Journal of infection, 2006, Volume: 52, Issue:4

    Topics: Acetamides; Aged; Anti-Infective Agents; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combina

2006
In vitro testing of gentamicin-vancomycin loaded bone cement to prevent prosthetic joint infection.
    Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia, 2005, Volume: 149, Issue:1

    Topics: Anti-Bacterial Agents; Arthroplasty, Replacement; Biofilms; Bone Cements; Gentamicins; Humans; In Vi

2005
High rate of aminoglycoside resistance among staphylococci causing prosthetic joint infection.
    Clinical orthopaedics and related research, 2005, Volume: 439

    Topics: Anti-Bacterial Agents; Bone Cements; Drug Resistance, Multiple, Bacterial; Gentamicins; Humans; Meth

2005
Permanent articulated antibiotic-impregnated cement spacer in septic shoulder arthroplasty: a case report.
    Journal of orthopaedic trauma, 2005, Volume: 19, Issue:9

    Topics: Aged; Bone Cements; Drug Implants; Female; Gentamicins; Humans; Joint Prosthesis; Prosthesis-Related

2005
Antibacterial and mechanical properties of bone cement impregnated with chitosan nanoparticles.
    Biomaterials, 2006, Volume: 27, Issue:11

    Topics: 3T3 Cells; Animals; Anti-Bacterial Agents; Biocompatible Materials; Biomechanical Phenomena; Bone Ce

2006
Staphylococcus aureus ulcer associated with continuous wear of silicone hydrogel contact lenses.
    Eye & contact lens, 2006, Volume: 32, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Cefazolin; Ciprofloxacin; Contact Lenses, Extended-Wear; Corneal Ulcer

2006
Conservative treatment of an early aortic graft infection due to Acinetobacter baumanii.
    Annals of vascular surgery, 2006, Volume: 20, Issue:3

    Topics: Acinetobacter baumannii; Aged; Anti-Bacterial Agents; Aortic Aneurysm, Abdominal; Blood Vessel Prost

2006
Two-stage revision of infected total knee replacements using articulating cement spacers and short-term antibiotic therapy.
    The Journal of bone and joint surgery. British volume, 2006, Volume: 88, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Bone Cements

2006
Gentamicin-loaded bioresorbable films for prevention of bacterial infections associated with orthopedic implants.
    Journal of biomedical materials research. Part A, 2007, Volume: 83, Issue:1

    Topics: Anti-Bacterial Agents; Bacteria; Bacterial Infections; Biofilms; Colony Count, Microbial; Gentamicin

2007
Effect of polyhexanide and gentamycin on human osteoblasts and endothelial cells.
    Swiss medical weekly, 2007, Mar-10, Volume: 137, Issue:9-10

    Topics: Alkaline Phosphatase; Anti-Bacterial Agents; Anti-Infective Agents, Local; Arthroplasty, Replacement

2007
Late prosthetic valve endocarditis due to Cardiobacterium hominis, an unusual complication.
    Indian journal of medical microbiology, 2007, Volume: 25, Issue:1

    Topics: Anti-Bacterial Agents; Cardiobacterium; Endocarditis, Bacterial; Gentamicins; Gram-Negative Bacteria

2007
Prosthetic valve endocarditis due to Neisseria elongata subsp. elongata in a patient with Klinefelter's syndrome.
    Journal of medical microbiology, 2007, Volume: 56, Issue:Pt 6

    Topics: Aged; Amoxicillin; Ceftriaxone; Diagnosis, Differential; DNA, Bacterial; DNA, Ribosomal; Endocarditi

2007
Implantable cardioverter-defibrillator infection due to Corynebacterium xerosis.
    International journal of cardiology, 2008, Aug-01, Volume: 128, Issue:1

    Topics: Anti-Bacterial Agents; Corynebacterium Infections; Defibrillators, Implantable; Device Removal; Drug

2008
Low relapse with oral antibiotics and two-stage exchange for late arthroplasty infections in 40 patients after 2-9 years.
    Acta orthopaedica, 2007, Volume: 78, Issue:4

    Topics: Administration, Oral; Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip

2007
Preliminary investigations on a new gentamicin and vancomycin-coated PMMA nail for the treatment of bone and intramedullary infections: An experimental study in the rabbit.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2008, Volume: 26, Issue:6

    Topics: Animals; Anti-Bacterial Agents; Biofilms; Bone Nails; Coated Materials, Biocompatible; Combined Moda

2008
In vitro study of the efficacy of acrylic bone cement loaded with supplementary amounts of gentamicin: effect on mechanical properties, antibiotic release, and biofilm formation.
    Acta orthopaedica, 2007, Volume: 78, Issue:6

    Topics: Acrylic Resins; Anti-Bacterial Agents; Bacterial Adhesion; Biofilms; Bone Cements; Gentamicins; Huma

2007
[One-stage revision operations for infection after hip arthroplasty].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2008, Volume: 22, Issue:1

    Topics: Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements; Combined Modality Therapy

2008
Incorporation of large amounts of gentamicin sulphate into acrylic bone cement: effect on handling and mechanical properties, antibiotic release, and biofilm formation.
    Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, 2008, Volume: 222, Issue:3

    Topics: Anti-Bacterial Agents; Biocompatible Materials; Biofilms; Bone Cements; Compressive Strength; Drug D

2008
[Replacement of infected total hip prosthesis in two stages].
    International orthopaedics, 1995, Volume: 19, Issue:3

    Topics: Anti-Bacterial Agents; Bone Cements; Gentamicins; Hip Prosthesis; Humans; Prosthesis-Related Infecti

1995
[Collagen with gentamicin in the treatment of an infected vascular prosthesis (case report)].
    Rozhledy v chirurgii : mesicnik Ceskoslovenske chirurgicke spolecnosti, 1994, Volume: 73, Issue:8

    Topics: Administration, Topical; Adult; Aorta, Abdominal; Blood Vessel Prosthesis; Collagen; Gentamicins; Hu

1994
Palacos gentamicin for the treatment of deep periprosthetic hip infections.
    Clinical orthopaedics and related research, 1994, Issue:298

    Topics: Aged; Bone Cements; Female; Follow-Up Studies; Gentamicins; Hip Prosthesis; Humans; Male; Methylmeth

1994
Revision of infected hip replacement. Two-stage procedure with a temporary gentamicin spacer.
    Acta orthopaedica Scandinavica, 1994, Volume: 65, Issue:1

    Topics: Aged; Bacterial Infections; Bone Cements; Cementation; Combined Modality Therapy; Female; Gentamicin

1994
Gentamicin sulfate attachment and release from anodized Ti-6A1-4V orthopedic materials.
    Journal of biomedical materials research, 1993, Volume: 27, Issue:7

    Topics: Alloys; Biocompatible Materials; Delayed-Action Preparations; Gentamicins; Microbial Sensitivity Tes

1993
Experimental implant-related osteomyelitis treated by antibiotic-calcium hydroxyapatite ceramic composites.
    The Journal of bone and joint surgery. British volume, 1993, Volume: 75, Issue:1

    Topics: Animals; Ceramics; Drug Carriers; Durapatite; Female; Gentamicins; Hydroxyapatites; Injections, Intr

1993
Sequential haematogenous infection of bilateral cementless total hip replacements.
    The Journal of bone and joint surgery. British volume, 1993, Volume: 75, Issue:1

    Topics: Drug Therapy, Combination; Female; Floxacillin; Gentamicins; Hip Prosthesis; Humans; Middle Aged; Pe

1993
Prosthetic hip infection and bacteremia due to Campylobacter jejuni in a patient with AIDS.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1993, Volume: 16, Issue:3

    Topics: AIDS-Related Opportunistic Infections; Bacteremia; Campylobacter Infections; Campylobacter jejuni; C

1993
The role of antibiotic-loaded cement in the treatment of an infection after a hip replacement.
    The Journal of bone and joint surgery. American volume, 1996, Volume: 78, Issue:3

    Topics: Bone Cements; Gentamicins; Hip Prosthesis; Humans; Methylmethacrylate; Methylmethacrylates; Prosthes

1996
Reimplantation of infected hip arthroplasties using bone allografts.
    Clinical orthopaedics and related research, 1997, Issue:335

    Topics: Adult; Aged; Anti-Bacterial Agents; Bone Cements; Bone Transplantation; Female; Gentamicins; Hip Pro

1997
Ciprofloxacin treatment of bacterial endocarditis involving prosthetic material after cardiac surgery.
    Archives of disease in childhood, 1997, Volume: 76, Issue:1

    Topics: Anti-Infective Agents; Blood Vessel Prosthesis; Child; Child, Preschool; Ciprofloxacin; Drug Therapy

1997
Tissue reactions to bacteria-inoculated rat lead samples. I. Effect of local gentamicin release through vicinal sponge or solution-dipping.
    Journal of biomedical materials research, 1997, Volume: 35, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Colony Count, Microbial; Drug Implants; Electrodes, Implanted; Genta

1997
Tissue reactions to bacteria-inoculated rat lead samples. II. Effect of local gentamicin release through surface-modified polyurethane tubing.
    Journal of biomedical materials research, 1997, Volume: 35, Issue:2

    Topics: Animals; Anti-Bacterial Agents; Drug Implants; Electrodes, Implanted; Gentamicins; Male; Muscle, Ske

1997
Management of infected total knee arthroplasty.
    Changgeng yi xue za zhi, 1997, Volume: 20, Issue:1

    Topics: Aged; Aged, 80 and over; Drug Therapy, Combination; Female; Follow-Up Studies; Gentamicins; Humans;

1997
Controlled release of antibiotics from biomedical polyurethanes: morphological and structural features.
    Biomaterials, 1997, Volume: 18, Issue:12

    Topics: Anti-Bacterial Agents; Bacterial Adhesion; Biocompatible Materials; Biofilms; Ciprofloxacin; Drug Im

1997
Successful treatment of Edwardsiella tarda prosthetic valve endocarditis in a patient with AIDS.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1997, Volume: 25, Issue:4

    Topics: Adult; AIDS-Related Opportunistic Infections; Ampicillin; Cefotaxime; Ciprofloxacin; Drug Therapy, C

1997
Conservative treatment of vascular graft infections in the groin.
    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 1997, Volume: 14 Suppl A

    Topics: Aged; Anti-Bacterial Agents; Aorta, Abdominal; Axillary Artery; Blood Vessel Prosthesis; Female; Fem

1997
Antibiotic treatment of streptococcal, enterococcal, and staphylococcal endocarditis. Working Party of the British Society for Antimicrobial Chemotherapy.
    Heart (British Cardiac Society), 1998, Volume: 79, Issue:2

    Topics: Anti-Bacterial Agents; Endocarditis, Bacterial; Gentamicins; Gram-Positive Bacterial Infections; Hea

1998
Treatment of osteomyelitis with antibiotic-soaked porous glass ceramic.
    The Journal of bone and joint surgery. British volume, 1998, Volume: 80, Issue:3

    Topics: Adult; Animals; Anti-Bacterial Agents; Apatites; Arthroplasty, Replacement, Hip; Calcium Compounds;

1998
A cement spacer for two-stage revision of infected implants of the hip joint.
    International orthopaedics, 1998, Volume: 22, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements; Drug I

1998
Antibiotic-loaded porous hydroxyapatite blocks for the treatment of osteomyelitis and postoperative infection. A preliminary report.
    Bulletin (Hospital for Joint Diseases (New York, N.Y.)), 1998, Volume: 57, Issue:3

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Biocompatible Materials; Combined Modality Therapy;

1998
The efficacy of controlled antibiotic release for prevention of polyethyleneterephthalate- (Dacron-) related infection in cardiovascular surgery.
    Clinical materials, 1993, Volume: 13, Issue:1-4

    Topics: Administration, Topical; Animals; Blood Vessel Prosthesis; Drug Delivery Systems; Fibrin Tissue Adhe

1993
Ultrasonic enhancement of antibiotic action on Escherichia coli biofilms: an in vivo model.
    Antimicrobial agents and chemotherapy, 1999, Volume: 43, Issue:5

    Topics: Animals; Biofilms; Escherichia coli; Female; Gentamicins; Prosthesis-Related Infections; Rabbits; Sk

1999
Treatment of infective and potentially infective complications of vascular bypass grafting using gentamicin with collagen sponge.
    Annals of the Royal College of Surgeons of England, 1999, Volume: 81, Issue:3

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Collagen; Female; Gentamicins; Humans; Male; Middle

1999
Investigation of the mechanism of the bioacoustic effect.
    Journal of biomedical materials research, 1999, Volume: 44, Issue:2

    Topics: Anti-Bacterial Agents; Biofilms; Biological Transport, Active; Cell Membrane; Gentamicins; Humans; I

1999
Pulsed ultrasound enhances the killing of Escherichia coli biofilms by aminoglycoside antibiotics in vivo.
    Antimicrobial agents and chemotherapy, 2000, Volume: 44, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Biofilms; Escherichia coli; Escherichia coli Infections; Gentamicins

2000
Method using urokinase and an antibiotic to avoid device removal in central venous catheter-related infections.
    Medical and pediatric oncology, 2000, Volume: 35, Issue:4

    Topics: Adolescent; Anti-Bacterial Agents; Bone Marrow Transplantation; Catheterization, Central Venous; Chi

2000
Gentamicin release from polymethylmethacrylate bone cements and Staphylococcus aureus biofilm formation.
    Acta orthopaedica Scandinavica, 2000, Volume: 71, Issue:6

    Topics: Anti-Bacterial Agents; Biofilms; Bone Cements; Drug Delivery Systems; Gentamicins; In Vitro Techniqu

2000
[Microbiological and immunological monitoring in polyarticular rheumatoid arthritis after total joint replacement].
    Deutsche medizinische Wochenschrift (1946), 2001, Feb-09, Volume: 126, Issue:6

    Topics: Anti-Bacterial Agents; Arthritis, Infectious; Arthritis, Rheumatoid; Arthroplasty, Replacement; Arth

2001
Optimization of the resistance of arterial allografts to infection: comparative study with synthetic prostheses.
    Annals of vascular surgery, 2001, Volume: 15, Issue:2

    Topics: Anti-Bacterial Agents; Aorta, Thoracic; Bacterial Adhesion; Bacterial Infections; Blood Vessel Prost

2001
Biomaterial-associated infection of gentamicin-loaded PMMA beads in orthopaedic revision surgery.
    The Journal of antimicrobial chemotherapy, 2001, Volume: 47, Issue:6

    Topics: Anti-Bacterial Agents; Bacteria; Biocompatible Materials; Cell Culture Techniques; Drug Resistance,

2001
[Experimental study of antiseptic (tauroline, taurolidine) and antibiotic (sulmycin implant) drugs in vascular prosthesis infections in a standardized infection model].
    Zentralblatt fur Chirurgie, 2001, Volume: 126, Issue:5

    Topics: Animals; Anti-Infective Agents, Local; Blood Vessel Prosthesis; Collagen; Femoral Artery; Gentamicin

2001
Impregnation of vancomycin, gentamicin, and cefotaxime in a cement spacer for two-stage cementless reconstruction in infected total hip arthroplasty.
    The Journal of arthroplasty, 2001, Volume: 16, Issue:7

    Topics: Adult; Aged; Anti-Bacterial Agents; Arthroplasty, Replacement, Hip; Bone Cements; Cefotaxime; Drug T

2001
In vitro adherence and accumulation of Staphylococcus epidermidis RP 62 A and Staphylococcus epidermidis M7 on four different bone cements.
    Langenbeck's archives of surgery, 2001, Volume: 386, Issue:5

    Topics: Analysis of Variance; Anti-Bacterial Agents; Bacterial Adhesion; Bacteriological Techniques; Bone Ce

2001
Long-term outcome of the 'Beefburger' procedure in patients unsuitable for two-stage revision following infected total knee replacement.
    The Knee, 2001, Volume: 8, Issue:4

    Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthroplasty, Replacement, Knee; Debridement; Drug D

2001
Use of antibiotic-impregnated bone cement nail to treat septic nonunion after open tibial fracture.
    The Journal of trauma, 2002, Volume: 52, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Bone Nails; Fracture Fixation, Intramedullary; Fractures, Open; Fractu

2002
Prosthetic hip-joint infection associated with a penicillin-tolerant group B streptococcus.
    The Journal of infection, 1992, Volume: 25, Issue:1

    Topics: Aged; Amoxicillin; Drug Therapy, Combination; Drug Tolerance; Gentamicins; Hip Prosthesis; Humans; M

1992
Prevention of graft infection by bonding of gentamycin to Dacron prostheses.
    Journal of vascular surgery, 1992, Volume: 15, Issue:1

    Topics: Analysis of Variance; Animals; Bacillus subtilis; Blood Vessel Prosthesis; Fibrin Tissue Adhesive; G

1992
Cavernous tissue antibiotic levels in penile prosthesis surgery.
    The Journal of urology, 1992, Volume: 147, Issue:5

    Topics: Aztreonam; Bacterial Infections; Gentamicins; Humans; Male; Penile Prosthesis; Penis; Prosthesis-Rel

1992