gentamicin and Infection, Postoperative Wound studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Research Excerpts

Excerpt	Relevance	Reference
"In a 3-year study, 103 children with acute non-perforated appendicitis who underwent appendicectomy were randomized for either a single preoperative dose of gentamicin and metronidazole or three doses of gentamicin and metronidazole given before and after the operation."	10.17	Antibiotic prophylaxis in acute non-perforated appendicitis in children: single dose of metronidazole and gentamicin. ( Saing, H; Tam, PK; Tsang, TM, 1992)
"The primary objective of this study was to compare triple therapy with ertapenem treatments in pediatric patients with perforated appendicitis, especially in terms of postoperative infectious complications."	9.19	Ertapenem versus standard triple antibiotic therapy for the treatment of perforated appendicitis in pediatric patients: a prospective randomized trial. ( Bayraktar, B; Celebi, S; Dalgic, N; Dokucu, AI; Kafadar, I; Kara, O; Karadag, CA; Pelit, S; Sancar, M, 2014)
"This article describes and discusses a prospective randomized study with gentamicin sulfate in the surgical treatment of hidradenitis suppurativa."	9.13	Surgical treatment of hidradenitis suppurativa with gentamicin sulfate: a prospective randomized study. ( Ankersmit, MF; Buimer, MG; Klinkenbijl, JH; Wobbes, T, 2008)
"Gentacoll (Schering-Plough A/S, DK-3520 Farum, Denmark) implant is a biologically absorbable collagen with gentamicin, which enables local use of gentamicin in an abscess cavity."	9.08	Primary suture of anorectal abscess. A randomized study comparing treatment with clindamycin vs. clindamycin and Gentacoll. ( Boné, J; Jaeger, G; Klaerke, M; Kraglund, K; Mortensen, J; Svane, S, 1995)
"A controlled, randomized trial with blind assessment of end points is described comparing ceftriaxone (1 g) given at induction of anesthesia with gentamicin (2 mg/kg) and metronidazole (500 mg) (GM), three times, every eight hours starting at induction, in preventing wound, chest, and urinary tract infections following bowel operations."	9.07	Ceftriaxone is more effective than gentamicin/metronidazole prophylaxis in reducing wound and urinary tract infections after bowel operations. Results of a controlled, randomized, blind clinical trial. ( Morris, WT, 1993)
"This prospective, randomized, double-blind study compares the efficacy, safety and cost-effectiveness of ampicillin, gentamicin and clindamycin (AGC) or cefotaxime and clindamycin (CC) for the treatment of children with complicated appendicitis."	9.07	A randomized clinical trial of ampicillin, gentamicin and clindamycin versus cefotaxime and clindamycin in children with ruptured appendicitis. ( Golladay, ES; Kaplan, S; King, DR; Mason, EO; Mollitt, DL; Pokorny, W; Schropp, KP; Wise, WE, 1991)
"Among patients with endomyometritis after cesarean section, a double-blind comparison of clindamycin-gentamicin versus cefamandole-placebo therapy was performed."	9.05	A double-blind, randomized comparison of clindamycin-gentamicin versus cefamandole for treatment of post-cesarean section endomyometritis. ( Blanco, JD; Castaneda, YS; Gibbs, RS; St Clair, PJ, 1982)
"The aim of this study was to investigate whether gentamicin-collagen (GC) sponges can lower the incidence of seroma and surgical site infections following breast cancer surgery."	7.88	Can Gentamicin-collagen Sponges Prevent Seroma Formation Following Mastectomy? ( de Wilt, JHW; Polat, F; Strobbe, LJA; Ten Wolde, B; van den Wildenberg, FJH, 2018)
"Patients with gangrenous or perforated appendicitis were treated with cefoxitin or a combination of clindamycin and gentamicin for a minimum of five post-operative days."	7.67	Antimicrobial management of surgically treated gangrenous or perforated appendicitis: comparison of cefoxitin and clindamycin-gentamicin. ( Levine, BA; Sirinek, KR, 1987)
"An animal model was used to evaluate and compare silver methacrylate with gentamicin methacrylate in experimental Staphylococcus osteomyelitis."	7.66	Silver antibacterial bone cement. Comparison with gentamicin in experimental osteomyelitis. ( Dueland, R; Rahn, BA; Spadaro, JA, 1982)
"Gentamicin (GM) was intramuscularly administrated to 25 patients with complicated urinary tract infections in doses of 20-120 mg a day for 4-16 days."	7.65	[Clinical experience with gentamicin in complicated urinary tract infections (author's transl)]. ( Aoyama, T; Furuya, S; Maruta, H; Mitobe, K; Tanda, H, 1976)
"Pilonidal sinus is common."	6.71	Efficacy and tolerance of a new gentamicin collagen fleece (Septocoll) after surgical treatment of a pilonidal sinus. ( Brückner, B; Grüssner, U; Holzer, B; Houf, M; Kiffner, E; Rosen, HR; Schildberg, FW; Vogel, P, 2003)
"Outcome measures were surgical site infection, wound healing, and recurrence."	6.53	Local administration of gentamicin collagen sponge in surgical excision of sacrococcygeal pilonidal sinus disease: a systematic review and meta-analysis of the literature. ( Davids, PH; Furnée, EJ; Nguyen, AL; Pronk, A; Pronk, AA; Smakman, N, 2016)
"In a 3-year study, 103 children with acute non-perforated appendicitis who underwent appendicectomy were randomized for either a single preoperative dose of gentamicin and metronidazole or three doses of gentamicin and metronidazole given before and after the operation."	6.17	Antibiotic prophylaxis in acute non-perforated appendicitis in children: single dose of metronidazole and gentamicin. ( Saing, H; Tam, PK; Tsang, TM, 1992)
"The primary objective of this study was to compare triple therapy with ertapenem treatments in pediatric patients with perforated appendicitis, especially in terms of postoperative infectious complications."	5.19	Ertapenem versus standard triple antibiotic therapy for the treatment of perforated appendicitis in pediatric patients: a prospective randomized trial. ( Bayraktar, B; Celebi, S; Dalgic, N; Dokucu, AI; Kafadar, I; Kara, O; Karadag, CA; Pelit, S; Sancar, M, 2014)
"Two hundred patients with gastric, bladder, or colorectal cancer were randomized to receive preoperative PA, group A received penicillin G sodium and gentamicin and group B received clindamycin and amikacin intravenously."	5.17	Comparing a combination of penicillin G and gentamicin to a combination of clindamycin and amikacin as prophylactic antibiotic regimens in prevention of clean contaminated wound infections in cancer surgery. ( El-Mahallawy, HA; El-Sayed Safa, MM; Hassan, SS; Khafagy, MM; Khalifa, HI, 2013)
"From the findings in this study, administration of preoperative gentamicin has a role in the prevention of wound infection after day case surgery for inguinal hernias in susceptible children."	5.13	The role of preoperative antibiotics in the prevention of wound infection after day case surgery for inguinal hernia in children in Ile Ife, Nigeria. ( Adejuyigbe, O; Ademuyiwa, OA; Bakare, TI; Sowande, OA; Usang, UE, 2008)
"This article describes and discusses a prospective randomized study with gentamicin sulfate in the surgical treatment of hidradenitis suppurativa."	5.13	Surgical treatment of hidradenitis suppurativa with gentamicin sulfate: a prospective randomized study. ( Ankersmit, MF; Buimer, MG; Klinkenbijl, JH; Wobbes, T, 2008)
"Gentacoll (Schering-Plough A/S, DK-3520 Farum, Denmark) implant is a biologically absorbable collagen with gentamicin, which enables local use of gentamicin in an abscess cavity."	5.08	Primary suture of anorectal abscess. A randomized study comparing treatment with clindamycin vs. clindamycin and Gentacoll. ( Boné, J; Jaeger, G; Klaerke, M; Kraglund, K; Mortensen, J; Svane, S, 1995)
" ISP was administered in combination with one of the second generation cephems among cefotiam (CTM), cefmetazole (CMZ), or cefuroxime (CXM) for 26 cases of wound infection and 7 cases of peritonitis."	5.08	[Combination use of second generation cephem and isepamicin for the treatment of post-surgical infection of the lower digestive tract]. ( Abe, M; Imaoka, Y; Kamiyama, Y; Kunii, Y; Masamune, R; Momono, S; Oouchi, K; Toyoda, T; Toyoshima, T; Watanabe, I, 1997)
"A controlled, randomized trial with blind assessment of end points is described comparing ceftriaxone (1 g) given at induction of anesthesia with gentamicin (2 mg/kg) and metronidazole (500 mg) (GM), three times, every eight hours starting at induction, in preventing wound, chest, and urinary tract infections following bowel operations."	5.07	Ceftriaxone is more effective than gentamicin/metronidazole prophylaxis in reducing wound and urinary tract infections after bowel operations. Results of a controlled, randomized, blind clinical trial. ( Morris, WT, 1993)
"5 g, every 6 hours) were compared with combined gentamicin (80 mg, every 8 hours) and metronidazole (500 mg every 6 hours) therapy in 246 patients hospitalized for penetrating abdominal injuries."	5.07	Piperacillin monotherapy compared with metronidazole and gentamicin combination in penetrating abdominal trauma. ( Ganesan, N; Lou, MA; Sims, EH; Thadepalli, H; Williams, SW, 1993)
"This prospective, randomized, double-blind study compares the efficacy, safety and cost-effectiveness of ampicillin, gentamicin and clindamycin (AGC) or cefotaxime and clindamycin (CC) for the treatment of children with complicated appendicitis."	5.07	A randomized clinical trial of ampicillin, gentamicin and clindamycin versus cefotaxime and clindamycin in children with ruptured appendicitis. ( Golladay, ES; Kaplan, S; King, DR; Mason, EO; Mollitt, DL; Pokorny, W; Schropp, KP; Wise, WE, 1991)
"Fifty-eight surgical patients suffering from severe bacterial infections caused by mezlocillin-sensitive, carbenicillin and/or gentamicin-resistant bacteria were treated with mezlocillin in 1980."	5.05	Mezlocillin in serious surgical infections caused by carbenicillin-resistant bacteria. ( Lewandowski, A; Orlowski, T; Weuta, H, 1982)
"Single doses of clindamycin hydrochloride and gentamicin sulfate given preoperatively, combined with intraoperative topical application of povidone-iodine were given to patients with perforated or gangrenous appendicitis."	5.05	Combined preoperative antibiotic therapy and intraoperative topical povidone-iodine. Reduction of wound sepsis following emergency appendectomy. ( Holl-Allen, RT; Sherlock, DJ; Ward, A, 1984)
"Among patients with endomyometritis after cesarean section, a double-blind comparison of clindamycin-gentamicin versus cefamandole-placebo therapy was performed."	5.05	A double-blind, randomized comparison of clindamycin-gentamicin versus cefamandole for treatment of post-cesarean section endomyometritis. ( Blanco, JD; Castaneda, YS; Gibbs, RS; St Clair, PJ, 1982)
"60 consecutive children operated for perforated appendicitis were treated randomly with either penicillin and streptomycin or with clindamycin and gentamycin."	5.05	Perforated appendix and antibiotics. ( Kekomäki, M; Louhimo, I, 1981)
"Thirteen publications were identified using the PubMed online database and search terms 'gentamicin-containing collagen implant' plus 'orthopaedic surgery', 'osteomyelitis', 'osteitis', 'amputation', 'surgical site infection' and 'wound infection'."	4.88	Local application of gentamicin-containing collagen implant in the prophylaxis and treatment of surgical site infection in orthopaedic surgery. ( Knaepler, H, 2012)
"The aim of this study was to investigate whether gentamicin-collagen (GC) sponges can lower the incidence of seroma and surgical site infections following breast cancer surgery."	3.88	Can Gentamicin-collagen Sponges Prevent Seroma Formation Following Mastectomy? ( de Wilt, JHW; Polat, F; Strobbe, LJA; Ten Wolde, B; van den Wildenberg, FJH, 2018)
"The aim of this study was to compare the efficacy of a gentamicin antibiotic intraoperative irrigation regimen (regimen A) with a povidone-iodine intraoperative irrigation regimen (regimen B) and to evaluate the ability of adjunctive local vancomycin powder (regimen C) to reduce the surgical site infection (SSI) rate following idiopathic scoliosis correction."	3.83	An intraoperative irrigation regimen to reduce the surgical site infection rate following adolescent idiopathic scoliosis surgery. ( Dare, CJ; Davies, EM; Evans, NR; van Herwijnen, B, 2016)
" Systemic antibiotics often do not reach "dead-space" hematomas where bacteria harbor after surgery, whereas local, controlled release gentamicin prophylaxis through PLGA microspheres showed favorable pharmacokinetics data to achieve local bactericidal concentrations for up to 7 days after surgery."	3.75	Reduction of postoperative spinal implant infection using gentamicin microspheres. ( Becker, E; Gelb, D; Ludwig, SC; Poelstra, KA; Stall, AC, 2009)
"To compare the infection rate after posterior spinal fusion with unit rod instrumentation with or without gentamicin-impregnated allograft bone in children with cerebral palsy (CP)."	3.74	Antibiotic-loaded allograft decreases the rate of acute deep wound infection after spinal fusion in cerebral palsy. ( Borkhuu, B; Borowski, A; Dabney, KW; Littleton, AG; Miller, F; Shah, SA, 2008)
" In the present study, piperacillin was compared with a combination of clindamycin and gentamicin for the treatment of 83 women with pelvic infection (42 with endometritis, 29 with posthysterectomy cuff infections, 11 with acute salpingitis, and one with a wound infection)."	3.67	Piperacillin versus clindamycin plus gentamicin for pelvic infections. ( Connor, KD; Gibbs, RS; Gilstrap, LC; Maier, RC; St Clair, PJ, 1984)
"In 10 cases of posttraumatic osteitis or osteomyelitis gentamicin-PMMA minichains have been used for treatment after radical local debridement."	3.67	[Medium term results of treatment of post-traumatic osteitis and osteomyelitis with gentamycin-PMMA minichains]. ( Quell, M; Vécsei, V, 1986)
"Patients with gangrenous or perforated appendicitis were treated with cefoxitin or a combination of clindamycin and gentamicin for a minimum of five post-operative days."	3.67	Antimicrobial management of surgically treated gangrenous or perforated appendicitis: comparison of cefoxitin and clindamycin-gentamicin. ( Levine, BA; Sirinek, KR, 1987)
"A compound of collagen and gentamicin was used in a controlled examination on 67 patients for the treatment of posttraumatic as well as postoperative osteomyelitis and, when applying cement-free endoprostheses, for hemostasis and local prevention of infection in the bed for implantation."	3.67	[Treatment of chronic osteomyelitis with a collagen-antibiotic compound--preliminary report]. ( Ascherl, R; Blümel, G; Erhardt, W; Lechner, F; Machka, K; Plaumann, L; Rupp, G; Sorg, KH; Stemberger, A, 1986)
"76 children were treated with clindamycin at a dosage of 40 mg/kg/day for postsurgical wound infections, sepsis, phlegmon, peritonitis, osteomyelitis, pneumonia, mediastinitis, pyoderma and urinary tract infections."	3.66	[Acute infections in pediatric surgery. Clinical experience with clindamycin (author's transl)]. ( Meier, H; Willital, GH, 1980)
"An animal model was used to evaluate and compare silver methacrylate with gentamicin methacrylate in experimental Staphylococcus osteomyelitis."	3.66	Silver antibacterial bone cement. Comparison with gentamicin in experimental osteomyelitis. ( Dueland, R; Rahn, BA; Spadaro, JA, 1982)
"In the present study, we used netilmicin for the postoperative complications and obtained the following results."	3.66	[Clinical effects of netilmicin]. ( Akagi, Y; Fukuda, H; Ito, A; Kawahara, T; Kimura, M; Nakano, Y; Okumura, T; Oshima, K; Shino, K; Tomita, K; Ueda, N; Yamaguchi, A, 1982)
" Children treated with ampicillin, gentamicin, and clindamycin had markedly fewer wound infections and abscesses and were able to tolerate a diet and go home sooner than those receiving ampicillin and/or gentamicin."	3.66	Rational use of antibiotics for perforated appendicitis in childhood. ( Buck, JR; David, IB; Filler, RM, 1982)
"Since the introduction of gentamicin (given both as a soaked sponge and as an injection below Tenon's capsule at the end of surgery) no case of early infection either with or without intraocular signs after operation for retinal detachment has occurred in a series of 206 cases comprising 243 operations."	3.65	Infection following retinal detachment surgery. ( Chignell, AH; Lean, JS, 1977)
"Gentamicin (GM) was intramuscularly administrated to 25 patients with complicated urinary tract infections in doses of 20-120 mg a day for 4-16 days."	3.65	[Clinical experience with gentamicin in complicated urinary tract infections (author's transl)]. ( Aoyama, T; Furuya, S; Maruta, H; Mitobe, K; Tanda, H, 1976)
"Patients who had noninstrumented open spine surgery were randomized into 2 groups."	3.30	Prevention of Surgical Site Infection Following Open Spine Surgery: The Efficacy of Intraoperative Wound Irrigation with Normal Saline Containing Gentamicin Versus Dilute Povidone-Iodine. ( Campbell, FC; Inojie, MO; Ndubuisi, CA; Ohaegbulam, SC; Okwunodulu, O, 2023)
"In congenital hydrocephalus patients submitted to VP shunt insertion, injection of prophylactic vancomycin and gentamicin in and around the shunt hardware significantly reduced the incidence of postoperative shunt infection."	2.82	Efficacy of postoperative antibiotic injection in and around ventriculoperitoneal shunt in reduction of shunt infection: A randomized controlled trial. ( Mohamed, MA; Moussa, WM, 2016)
"The mean diameter of scar at the 5th to 8th week review appointments was almost similar between the group with dressing (3."	2.80	Randomized Controlled Trial comparing Dressing and No Dressing of Surgical Wound after Cleft Lip Repair. ( Gbolahan, OO; Ogunmuyiwa, SA; Osinaike, BB, 2015)
"In patients without anastomotic leakage, the risk of organ space SSI was significantly reduced in patients who received GCI: 2."	2.79	Surgical site infections following short-term radiotherapy and total mesorectal excision: results of a randomized study examining the role of gentamicin collagen implant in rectal cancer surgery. ( Bednarczyk, M; Byszek, A; Chwalinski, M; Oledzki, J; Olesiński, T; Pietrzak, L; Rutkowski, A; Saramak, P; Szpakowski, M; Zając, L, 2014)
" This study aimed to determine the comparative efficacy of a single dose of gentamicin in combination with metronidazole versus multiple doses for prevention of post-caesarean infection."	2.78	Single dose of gentamicin in combination with metronidazole versus multiple doses for prevention of post-caesarean infection at Bugando Medical Centre in Mwanza, Tanzania: a randomized, equivalence, controlled trial. ( Kidenya, BR; Konje, ET; Lyimo, FM; Massinde, AN; Mshana, SE, 2013)
" This study aims to determine the comparative efficacy of a single dose of gentamicin in combination with metronidazole versus multiple doses for prevention of post caesarean infection."	2.77	Efficacy of single dose of gentamicin in combination with metronidazole versus multiple doses for prevention of post-caesarean infection: study protocol for a randomized controlled trial. ( Kidenya, BR; Konje, E; Lyimo, FM; Massinde, AN; Mshana, SE, 2012)
"112 patients with primary rectal cancer were enrolled in this study."	2.77	Local antibiotic therapy in rectal cancer surgery. ( Dziki, A; Kołacińska, A; Morawiec, Z; Pawlak, M, 2012)
"Pilonidal sinus is common."	2.71	Efficacy and tolerance of a new gentamicin collagen fleece (Septocoll) after surgical treatment of a pilonidal sinus. ( Brückner, B; Grüssner, U; Holzer, B; Houf, M; Kiffner, E; Rosen, HR; Schildberg, FW; Vogel, P, 2003)
" A pharmacodynamic analysis was conducted using data from a previous prospective, randomized, double-blind clinical study which compared two dosage regimens of gentamicin plus metronidazole for prophylaxis in connection with elective colorectal surgery."	2.70	Antibiotic pharmacodynamics in surgical prophylaxis: an association between intraoperative antibiotic concentrations and efficacy. ( Ariano, RE; Harding, GK; Silverman, RE; Zelenitsky, SA, 2002)
"Surgical wound infections were significantly reduced by the collagen-gentamicin implant."	2.69	Effectiveness of collagen-gentamicin implant for treatment of "dirty" abdominal wounds. ( Delgado, FJ; Guerrero, TS; Guzmán Valdivia Gomez, G; Lluck, MC, 1999)
" Thus, daily dosing of gentamicin was found to be safe, effective, and cost efficient in the treatment of open fractures when combined with a cephalosporin and aggressive operative debridement and stabilization."	2.69	Once daily, high dose versus divided, low dose gentamicin for open fractures. ( Bjornson, SH; Cockrin, J; Kirk, PG; Levy, MS; Ruhnke, CJ; Sorger, JI; Tang, P, 1999)
"We compared postoperative wound infection rates in 221 colorectal surgery patients randomized to receive systemic gentamicin/metronidazole with (Group I, n = 107) or without (Group II, n = 114) the gentamicin-collagen sponge."	2.68	Prevention of wound infection in elective colorectal surgery by local application of a gentamicin-containing collagen sponge. ( Nijhuis, PH; Rutten, HJ, 1997)
"Metronidazole-gentamicin was given as 500 mg of metronidazole plus 120 mg of gentamicin in a minibag."	2.68	A double-blind, randomized study of three antimicrobial regimens in the prevention of infections after elective colorectal surgery. ( Chow, A; Danforth, D; Frighetto, L; Jewesson, P; Nickoloff, D; Pezim, M; Schwartz, L; Sleigh, K; Smith, J; Stiver, G; Stoller, J; Wai, A, 1997)
"Gentamicin-PMMA chains have been demonstrated to exert a favorable effect on local wound healing and the postoperative outcome of patients with abdominoperineal rectum excision."	2.67	Local gentamicin application for perineal wound healing following abdominoperineal rectum excision. ( Czerwenka, E; Marczell, AP; Rosen, HR; Spoula, H; Stierer, MO; Wasl, H, 1991)
"In 3 patients (one patient in each treatment group) a postoperative wound infection was documented."	2.66	A comparative study of cefotaxime sodium versus a combination of cefapirin and gentamicin in the prophylactic treatment of patients undergoing cholecystectomy. ( Akbary, MA; Chen, JS; Hou, MF; Ker, CG; Lee, KT; Sheen, PC, 1989)
"Cefazolin was significantly less effective than cefamandole at both the sternal (1."	2.66	Efficacy of cefazolin, cefamandole, and gentamicin as prophylactic agents in cardiac surgery. Results of a prospective, randomized, double-blind trial in 1030 patients. ( Alford, WC; Burrus, GR; Glassford, DM; Kaiser, AB; Kernodle, DS; Lea, JW; Petracek, MR; Roach, AC; Stoney, WS; Thomas, CS, 1987)
" There is no general agreement as to which antibiotic or combination of antibiotics to use or what the schedule of dosage administration should be."	2.65	Antimicrobial prophylaxis for contaminated head and neck surgery. ( Johnson, JT; Myers, EN; Schramm, VL; Sigler, BA; Thearle, PB, 1984)
"The gentamicin was given at the time of anaesthetic premedication, the operations were performed by either of two surgeons, and the patients were followed up by an independent investigator."	2.64	Prophylactic use of gentamicin in colonic and rectal surgery. ( Burton, RC; Cuthbertson, AM; Hughes, ES, 1975)
"Nevertheless, gram-negative infections appeared more likely to be susceptible to tobramycin than to gentamicin."	2.64	Treatment of surgical infections with tobramcin. ( Currie, CA; Geheber, CE; Kolb, LD; Stone, HH, 1975)
"Outcome measures were surgical site infection, wound healing, and recurrence."	2.53	Local administration of gentamicin collagen sponge in surgical excision of sacrococcygeal pilonidal sinus disease: a systematic review and meta-analysis of the literature. ( Davids, PH; Furnée, EJ; Nguyen, AL; Pronk, A; Pronk, AA; Smakman, N, 2016)
"Gentamicin was administered using sponges (n = 3), beads (n = 4), and by local injection (n = 1)."	2.52	Local Application of Gentamicin in the Prophylaxis of Perineal Wound Infection After Abdominoperineal Resection: A Systematic Review. ( Bemelman, WA; Burger, JW; Buskens, CJ; Musters, GD; Tanis, PJ, 2015)
"The development of surgical site infection (SSI) following vascular surgery is an important issue for healthcare providers as it has serious implications for both patient morbidity and mortality."	2.48	Local application of gentamicin-containing collagen implant in the prophylaxis and treatment of surgical site infection following vascular surgery. ( Hussain, ST, 2012)
"Deep-space surgical site infections carry significant morbidity and mortality."	1.72	Gentamicin-Containing Collagen Implant May Reduce Surgical Site Infections After Open Infrainguinal Arterial Revascularization. ( Garbowski, MW; Hockley, JA; Jacques, A; Jansen, SJ; Kwok, CHR; Stopher, L; Zhao, AH, 2022)
"The frequency of surgical site infection (SSI) following orthopaedic implant placement in horses has been reported but not compared with respect to specific antibiotic protocols administered."	1.72	Evaluation of factors associated with surgical site infection in equine proximal interphalangeal joint arthrodesis: 54 cases (2010-2019). ( Daniels, A; Griffenhagen, GM; Hendrickson, DA; Pezzanite, LM, 2022)
" Sterilization being an essential pre-requisite for the dosage form was carried out using ethylene oxide."	1.56	In vitro and in vivo evaluation of gentamicin sulphate-loaded PLGA nanoparticle-based film for the treatment of surgical site infection. ( Dhal, C; Mishra, R, 2020)
"Open fractures are at significant risk of developing a fracture-related infection, despite the routine administration of perioperative antibiotic prophylaxis."	1.56	Local Application of a Gentamicin-Loaded Hydrogel Early After Injury Is Superior to Perioperative Systemic Prophylaxis in a Rabbit Open Fracture Model. ( Arens, D; D'Este, M; Deimling, C; Eglin, D; Metsemakers, WJ; Morgenstern, M; Moriarty, TF; Puetzler, J; Richards, RG; Vallejo Diaz, A; Zeiter, S, 2020)
"Cumulative incidence of surgical site infection was 2."	1.51	Adequacy of antibiotic prophylaxis protocol in appendectomies in children. ( Durán-Poveda, M; García-Cruces, J; Gil-Yonte, P; Rodríguez-Caravaca, G; Rodríguez-Villar, D; Román-Montero, JS, 2019)
"Deep surgical site infections occurred in 3 fresh fractures and two in revision surgeries."	1.46	Clinical experiences in the use of a gentamicin-coated titanium nail in tibia fractures. ( Kerstan, M; Raschke, M; Schmidmaier, G; Schwabe, P; Südkamp, N, 2017)
"No gentamicin use was observed during the final 40 weeks of the post-intervention period."	1.46	Discontinuation of peri-operative gentamicin use for indwelling urinary catheter manipulation in orthopaedic surgery. ( Bond, SE; Boutlis, CS; Jansen, SG; Miyakis, S, 2017)
"Antibiotic administration during the treatment of open fractures has been shown to reduce infection rates and is considered a critical step in the management of these injuries."	1.43	Antibiotic related acute kidney injury in patients treated for open fractures. ( Banks, K; Hahn, J; Inaba, K; Marecek, GS; Pannell, WC, 2016)
"In liver transplant (LT) recipients, surgical site infection (SSI) represents an important cause of morbidity and mortality."	1.43	Impact of a Multimodal Approach in Prevention of Surgical Site Infection in Hepatic Transplant Recipients. ( Abelleira, M; Castelli, J; Etlin, A; Gerona, S; González, LS; Grecco, G; Harguindeguy, M; Iglesias, C; Leites, A; López, M; Medina, JC; Menéndez, J; Prieto, J; Rando, K; Scalone, P; Valverde, M, 2016)
"Cefazolin alone was less effective in preventing infection compared with the other antibiotic regimens (p = 0."	1.39	Differences in sacral neuromodulation device infection rates based on preoperative antibiotic selection. ( Atiemo, HO; Cameron, AP; Clemens, JQ; Haraway, AM; He, C; Stroup, C, 2013)
"Postoperative surgical site infection (SSI) can be considered a frequent complication of hand-assisted laparoscopic donor nephrectomy (HALDN)."	1.39	Effect of gentamicin-containing collagen sponges on surgical site infection after hand-assisted laparoscopic donor nephrectomy. ( Alberts, VP; Bemelman, FJ; Idu, MM; Minnee, RC; van Donselaar-van der Pant, KA, 2013)
"Nosocomial infections are a matter of concern in surgical wards."	1.37	Emergence of vancomycin-resistant Staphylococcus aureus identified in the Tlemcen university hospital (North-West Algeria). ( Abdelali, S; Abdelouahid, DE; Azzaoui, H; Rahmoun, M; Rebiahi, SA, 2011)
"We report a case of mediastinitis successfully treated with autovaccine therapy, once conventional surgical and medical therapies had failed."	1.34	Efficacy of autovaccination therapy on post-coronary artery bypass grafting methicillin-resistant Staphylococcus aureus mediastinitis. ( Brancaccio, G; De Vito, D; Rizzo, C; Rizzo, G, 2007)
" The effect of intraoperative blood loss on gentamicin concentrations and its pharmacokinetic properties was determined."	1.32	Effects of blood loss and fluid volume replacement on serum and tissue gentamicin concentrations during colorectal surgery. ( Kostopanagiotou, G; Markantonis, SL; Panidis, D; Smirniotis, V; Voros, D, 2004)
"The mean age of patients with a surgical site infection ranged from 12 to 15."	1.31	A retrospective review of three antibiotic prophylaxis regimens for pediatric cardiac surgical patients. ( Bove, EL; Chenoweth, CE; Kulik, TJ; Maher, KO; Mosca, RS; VanDerElzen, K, 2002)
"434 patients underwent acoustic neuroma surgery in the Otorhinolaryngology Division, A."	1.31	Short-term antibiotic prophylaxis for the prevention of wound infection and secondary meningitis in acoustic neuroma surgery: a ten-year experience in a regional hospital. ( Arosio, M; Farina, C; Lorenzi, N; Mazzoni, A; Minola, E; Zappone, C, 2000)
"The outcome indicator was the surgical site infection rate."	1.31	Reducing infections among women undergoing cesarean section in Colombia by means of continuous quality improvement methods. ( Angel, E; Fuentes, JM; Gaitan, H; Goethe, B; Goldmann, DA; Hellerstein, S; Huskins, WC; Lozano, FW; Parra, S; Ross-Degnan, D; Ruiz, AI; Weinberg, M, 2001)
"Sixteen patients were identified in whom once daily gentamicin dosing was used as part of an antibiotic prophylaxis regimen in patients with types II and III open tibial shaft fractures."	1.31	Once daily high-dose gentamicin to prevent infection in open fractures of the tibial shaft: a preliminary investigation. ( King, C; May, CG; Pearsall, AW; Russell, GV, 2001)
" Specific physiologic criteria of sepsis may be used to identify critically ill patients who will most likely benefit from aggressive initial aminoglycoside dosing when these drugs are used to treat gram-negative infections."	1.30	Aminoglycoside levels in critically ill surgical patients: the implications of physiologic criteria of sepsis. ( Asensio, JA; Belzberg, H; Berne, TV; Cornwell, EE; Demetriades, D; Henriques, G; Kern, JW, 1997)
"Chronic suppuration is a reverting problem in surgical practice."	1.30	Experience acquired by applying gentamicin-sponge. ( Faludi, S; Jakab, F; Kádár, E; Kószegi, G, 1997)
"Only two relapse were seen, which had to be re-opened."	1.30	[Is primary would closure in septic pediatric surgery contraindicated?]. ( Beiler, HA; Benz, G; Daum, R; Schäfer, K, 1997)
"The postoperative complications were suppuration of the wall (n = 4), intestinal fistula (n = 3), evisceration, and residual abscess."	1.29	[Typhoid perforations: experiences in a surgical setting in Cameroon. Apropos of 49 cases]. ( Ibile, A; Malonga, E; Masso-Misse, P; Yao, JG, 1994)
"Surgical wound infections were found in the group receiving ampicillin and sulbactam in 20% of cases, and in the control group in 13."	1.29	[Prophylactic use of ampicillin and sulbactam in colonic surgery]. ( Andziak, P; Bednarska, I; Mendelska, K, 1994)
"Gentamicin-PMMA chains are an effective drug delivery system for local antibiotic therapy in bone and soft-tissue infections."	1.29	Antibiotic bead chains. ( Klemm, KW, 1993)
"The most serious complications in the treatment of open fractures and after procedures on bone tissue are infections."	1.28	[Cephalosporin antibiotics from the firm Glaxo in treatment of patients with complications after trauma]. ( Kateusz, J; Misterka, S, 1992)
"Fourteen patients with localised groin wound graft infection after vascular reconstruction were included in this study to evaluate the clinical effect and the pharmacokinetic profile of gentamycin containing collagen for local antibiotic treatment."	1.28	Clinical and pharmacokinetic evaluation of gentamycin containing collagen in groin wound infections after vascular reconstruction. ( Jørgensen, LG; Lorentzen, JE; Sørensen, TS, 1991)
"The success rate without recurrence of osteomyelitis or soft tissue infection was 95% in this study at an average of 16 months after surgery."	1.28	Local antibiotic treatment of soft tissue and bone infections of the foot. ( Jacobs, AM; Stabile, DE, 1990)
"Follow-up of 74 patients with bacterial arthritis and osteomyelitis are conducted in order to prove the effect of the application of Gentamycin-PMMA-chains (20 infections after implants of hip joint arthroplastic, 11 nonspecific coxitis, 10 gonitis and 33 osteomyelitis)."	1.28	[Personal experiences with the application of septopal chains in the treatment of bacterial arthritis and osteomyelitis]. ( Schuckmann, P; Schuckmann, W, 1989)
"We reviewed 50 gastric cancer operations during the period from September 1984 to August 1985."	1.28	[Postoperative wound infections in surgery of stomach cancer. A bacteriologic analysis]. ( Röthig, W; Widow, VW; Wilhelm, R, 1989)
"In continuation of our clinical observations on perioperative prophylaxis by application of Halospor and Gentamicin the dosage of Halospor has been reduced to 2 grams once only."	1.27	[Once again: the perioperative antibiotic prophylaxis in cesarean section]. ( Bellée, H; Fiedler, FB; Link, M, 1988)
"Amikacin has been traditionally reserved for culture-proved infections due to gram-negative organisms resistant to gentamicin or other aminoglycosides."	1.27	Three-year experience with amikacin sulfate as an exclusive surgical aminoglycoside in a large acute-care hospital. ( Lee, JT, 1985)
"A retrospective and a prospective group of 38 and 20 patients respectively were studied with regard to bacterial strains, clinical effect, toxic side effects and serum concentration of gentamicin in severe surgical infections."	1.26	Gentamicin treatment in severe surgical infections--serum levels, interactions, toxicity and efficacy. ( Athlin, L; Domellöf, L; Holm, S, 1981)
"Intra-abdominal infection developed in 7 of 21 (33%) who had a persistent leukocytosis, but no intra-abdominal infections developed after operation in 30 patients who had normal WBC counts at the end of antibiotic treatment (p less than 0."	1.26	Implications of leukocytosis and fever at conclusion of antibiotic therapy for intra-abdominal sepsis. ( Dellinger, EP; Lennard, ES; Minshew, BH; Wertz, MJ, 1982)
"Netilmicin was administered either with or without antibiotics."	1.26	[A clinical study of netilmicin in patients of surgical field (author's transl)]. ( Asano, T; Hayashi, R; Nishijima, H; Ochiai, T; Ohtsuka, M; Sakamoto, K; Sato, H; Suzuki, T; Watanabe, K, 1982)
"Infectious complications of hydrocephalus shunts are serious problems."	1.26	[External ventricular drainage: a possible method of treating cerebrospinal shunt infections and ventriculitis (author's transl)]. ( Grubbauer, HM; Oberbauer, RW, 1981)
"150 gentamicin-PMMA-beads were implanted (+ 160 mg gentamicin i."	1.26	Treatment of a patient with impaired renal function with gentamicin-PMMA-beads. ( Vree, TB; Walenkamp, GH, 1981)
"A study of 113 patients with septic shock admitted to an intensive therapy unit (I."	1.26	Prospective study of the treatment of septic shock. ( Ledingham, IM; McArdle, CS, 1978)
"Netilmicin may prove to be a useful agent, particularly for infections due to multiresistant Klebsiella or Serratia, or when prolonged aminoglycoside therapy is required."	1.26	Therapeutic experience with netilmicin. ( Bruce, AW; Chadwick, P; Cooke, TD; Hardy, GJ, 1978)
"Gentamicin and Keflin were eluted from the cylinders in sufficient quantities to completely eliminate or markedly reduce the number of bacteria recovered from infected areas."	1.26	Antibiotics in acrylic bone cement. In vivo studies. ( Welch, AB, 1978)
"Twenty-three cases of mediastinitis after cardiac surgery in children were treated by us between 1973 and 1976."	1.26	Treatment of mediastinitis in children after cardiac surgery. A study of 20 cases. ( Barois, A; Bourda, JL; Chapuis, C; Combes, A; Goulon, M; Grosbuis, S; Simon, N, 1978)
"Gentamicin (GM) was intramuscularly administered to 24 patients with various infections (including 1 for prophylaxis of a postoperative infection) in the dose of 40 mg X 2/day for 4-26 days."	1.26	[Clinical use of gentamicin in the field of surgery (author's transl)]. ( Ishii, T; Kishi, D; Nakai, S; Sugihara, H; Yokoyama, T, 1976)
"The attack rate of nosocomial infections declined from approximately 12 to approximately 3 per cent and wound infections occurred in only seven of 811 patients."	1.25	Antibiotics as an aid in the prevention of infections after peripheral arterial surgery. ( Perdue, GD, 1975)
" If it is used a high dosage is necessary because the bone levels which we investigated were very low."	1.25	[Gentamicin in orthopedic surgery]. ( Krämer, J; Maassen, H; Rosin, H, 1975)

Research

Studies (676)

Authors

Clinical Trials (30)

Trial Overview

Trial Outcomes

Number of Infections in Each Study Arm

Timeframe	Studies, this research(%)	All Research%
pre-1990	347 (51.33)	18.7374
1990's	98 (14.50)	18.2507
2000's	67 (9.91)	29.6817
2010's	134 (19.82)	24.3611
2020's	30 (4.44)	2.80

Authors	Studies
Ali Md Frcs C-Th, I	1
Mourad Md Frcs C-Th, F	1
Zhao, AH	1
Kwok, CHR	1
Jacques, A	1
Stopher, L	1
Hockley, JA	1
Garbowski, MW	1
Jansen, SJ	1
Baddour, LM	1
Garrigos, ZE	1
Vos, RJ	1
van Putte, BP	1
de Mol, BAJM	1
Hoogewerf, M	1
Mandigers, TJ	1
Kloppenburg, GTL	1
Servito, M	1
Khani-Hanjani, A	1
Smith, KM	1
Tsuyuki, RT	1
Mullen, JC	1
Lee, KY	1
Lee, J	1
Park, YY	1
Oh, ST	1
Daniels, A	1
Pezzanite, LM	1
Griffenhagen, GM	1
Hendrickson, DA	1
Xu, T	1
Wu, KL	1
Jie, K	1
Wojcik, M	1
Kazimierczak, P	1
Belcarz, A	1
Wilczynska, A	1
Vivcharenko, V	1
Pajchel, L	1
Adaszek, L	1
Przekora, A	1
Shaffer, A	1
Naik, A	1
MacInnis, B	1
Chen, M	2
Ivankovic, S	1
Paisan, G	1
Garst, JR	1
Hassaneen, W	1
Arnold, PM	1
Ashkenazi, I	1
Amzallag, N	1
Snir, N	1
Morgan, S	1
Garceau, S	1
Kotz, L	1
Gold, A	1
Warschawski, Y	1
Inojie, MO	1
Okwunodulu, O	1
Ndubuisi, CA	1
Campbell, FC	1
Ohaegbulam, SC	1
Wang, X	1
Fu, L	1
Guo, S	1
Fang, X	1
Pinto, D	1
Manjunatha, K	1
Savur, AD	1
Ahmed, NR	1
Mallya, S	1
Ramya, V	1
Naresh-Babu, J	1
Arun-Kumar, V	1
Thomassen, MB	1
Hanberg, P	1
Stilling, M	1
Petersen, KK	1
Søballe, K	1
Krag, LB	1
Højskov, CS	1
Bue, M	1
Wübbeke, LF	2
Telgenkamp, B	1
van Boxtel, T	1
Bolt, LJJ	1
Houthoofd, S	1
Vriens, PWHE	1
Bouwman, LH	1
Mees, BME	2
Daemen, JWHC	2
Dhal, C	2
Mishra, R	2
Vallejo Diaz, A	1
Deimling, C	1
Morgenstern, M	1
D'Este, M	1
Puetzler, J	1
Zeiter, S	1
Arens, D	1
Metsemakers, WJ	2
Richards, RG	1
Eglin, D	1
Moriarty, TF	1
Zaidi, S	1
Jaipersad, A	1
Pherwani, A	1
Rajagopalan, S	1
Finger, T	1
Schaumann, A	1
Pennacchietti, V	1
Bührer, C	1
Thomale, UW	1
Schulz, M	1
Emile, SH	1
Elfallal, AH	1
Abdel-Razik, MA	1
El-Said, M	1
Elshobaky, A	1
Akay, S	1
Akay, H	1
Man, J	1
Choy, B	1
Li, YD	1
MaiMaiTiABuDuLa, M	1
Cao, GQ	1
MaiMaiTiAiLi, M	1
Zhou, XH	1
Lu, YM	1
Zhang, JH	1
Xing, Q	1
Wu, CJ	1
Feng, M	1
Zhang, GG	1
Tang, BP	1
Chiarello, MM	1
Brisinda, G	1
De Meo, D	1
Cannari, FM	1
Petriello, L	1
Persiani, P	1
Villani, C	1
Magro, PL	1
Sousa Uva, M	1
Alshoubaki, O	1
Al Darabaa, Z	1
Odat, O	1
Qubbaj, A	1
Alhyari, R	1
Alshare, S	1
Ghanma, I	1
Illiano, E	1
Trama, F	1
Crocetto, F	1
Califano, G	1
Aveta, A	1
Motta, G	1
Pastore, AL	1
Brancorsini, S	1
Fabi, C	1
Costantini, E	1
Andreas, M	1
Muckenhuber, M	1
Hutschala, D	1
Kocher, A	1
Thalhammer, F	1
Vogt, P	1
Fleck, T	1
Laufer, G	1
Zawadzki, PJ	1
Perkowski, K	1
Kotlarski, M	1
Pietruczuk-Padzik, A	1
Chomicz, L	1
Schmidmaier, G	4
Kerstan, M	1
Schwabe, P	1
Südkamp, N	1
Raschke, M	1
Suh, I	1
Long, SA	1
Coe, J	1
Koehler, J	1
Fry, D	1
Welton, ML	1
Manning, S	1
Ugahary, LC	1
Lindstedt, EW	1
Wubbels, RJ	1
van Dissel, JT	1
Jansen, JTG	1
Gan, I	1
van Goor, AT	1
Bennebroek, CA	1
van der Werf, DJ	1
Ossewaarde-van Norel, A	1
Mayland Nielsen, CC	1
Tilanus, M	1
van den Biesen, PR	1
Schellekens, PA	1
La Heij, E	1
Faridpooya, K	1
van Overdam, K	1
Veckeneer, M	1
van Meurs, JC	1
Kenna, DM	1
Irojah, BB	1
Mudge, K	1
Eveler, K	1
Sihra, N	1
Aboelsoud, M	1
Oliyide, A	1
Counsell, A	1
Gall, Z	1
Cooper, C	1
Horner, C	1
Barlow, G	1
Stryja, J	1
Sandy-Hodgetts, K	1
Guise, T	1
Humphreys, H	1
Ten Wolde, B	1
van den Wildenberg, FJH	1
Polat, F	1
de Wilt, JHW	1
Strobbe, LJA	1
Fatula, LK	1
Nelson, A	1
Abbad, H	1
Ewing, JA	1
Hancock, BH	1
Cobb, WS	1
Carbonell, AM	1
Warren, JA	1
Folse, J	1
Hill, CE	1
Graves, ML	1
Russell, GV	2
Hydrick, J	1
Jones, LC	1
Replogle, WH	1
Bergin, PF	1
Spitler, CA	1
Hoogerboord, CM	1
Cwinn, M	1
Minor, SF	1
Makker, K	1
Lamba, AK	1
Faraz, F	1
Tandon, S	1
Sheikh Ab Hamid, S	1
Aggarwal, K	1
Chowdhri, K	1
Durán-Poveda, M	1
Gil-Yonte, P	1
Rodríguez-Villar, D	1
García-Cruces, J	1
Rodríguez-Caravaca, G	1
Román-Montero, JS	1
Raven, TF	1
Moghaddam, A	2
Ermisch, C	1
Westhauser, F	1
Heller, R	1
Bruckner, T	2
Weichman, KE	1
Levine, SM	1
Wilson, SC	1
Choi, M	1
Karp, NS	1
Chang, WK	1
Srinivasa, S	1
MacCormick, AD	1
Hill, AG	1
El-Mahallawy, HA	1
Hassan, SS	1
Khalifa, HI	1
El-Sayed Safa, MM	1
Khafagy, MM	1
Freeman, DE	1
Garnier, M	1
Blayau, C	1
Fulgencio, JP	1
Baujat, B	1
Arlet, G	1
Bonnet, F	1
Quesnel, C	1
Ng, T	1
Unadkat, J	1
Bilonick, RA	1
Wollstein, R	1
Magnan, B	1
Bondi, M	1
Vecchini, E	1
Samaila, E	1
Maluta, T	1
Dall'Oca, C	1
Haraway, AM	1
Clemens, JQ	1
He, C	1
Stroup, C	1
Atiemo, HO	1
Cameron, AP	1
Rahman, A	1
Hossain, MA	1
Paul, SK	1
Sultana, S	1
Haque, N	1
Kabir, MR	1
Hoque, SM	1
Lyimo, FM	2
Massinde, AN	2
Kidenya, BR	2
Konje, ET	1
Mshana, SE	2
Okapa, R	1
Marczyński, W	1
Kolbuszewski, A	1
Martin, E	1
Paniker, J	1
White, RW	1
West, R	1
Howard, P	1
Sandoe, J	1
Madsboell, TK	1
Vestergaard, RF	1
Andelius, TC	1
Hauge, EM	1
Hasenkam, JM	1
Alberts, VP	1
Minnee, RC	1
Bemelman, FJ	1
van Donselaar-van der Pant, KA	1
Idu, MM	1
Penn-Barwell, JG	1
Murray, CK	1
Wenke, JC	1
Dalgic, N	1
Karadag, CA	1
Bayraktar, B	1
Sancar, M	1
Kara, O	1
Pelit, S	1
Celebi, S	1
Kafadar, I	1
Dokucu, AI	1
Ross, AD	1
Boscainos, PJ	1
Malhas, A	1
Wigderowitz, C	1
Yang, CH	1
Chew, KY	1
Solomkin, JS	1
Lin, PY	1
Chiang, YC	1
Kuo, YR	1
Wang, EH	1
Rubio, DA	1
Jettoo, P	1
Jeavons, R	1
Siddiqui, B	1
O'Brien, S	1
Terry, J	1
Neethirajan, S	1
Bailey, O	1
Torkington, MS	1
Anthony, I	1
Wells, J	1
Blyth, M	1
Jones, B	1
Benito-González, F	1
Benito, J	1
Sánchez, LA	1
Estevez Alonso, S	1
Muñoz Herrera, A	1
Batuecas-Caletrio, A	1
Formanek, MB	1
Herwaldt, LA	1
Perencevich, EN	1
Schweizer, ML	1
Benedetto, U	1
Raja, SG	5
Rutkowski, A	1
Zając, L	1
Pietrzak, L	1
Bednarczyk, M	1
Byszek, A	1
Oledzki, J	1
Olesiński, T	1
Szpakowski, M	1
Saramak, P	1
Chwalinski, M	1
Mishra, PK	1
Ashoub, A	1
Salhiyyah, K	2
Aktuerk, D	1
Ohri, S	1
Luckraz, H	1
Biondo, S	1
Pochhammer, J	1
Zacheja, S	1
Schäffer, M	1
Costa Almeida, CE	1
Reis, L	1
Carvalho, L	1
Costa Almeida, CM	1
Chen, AF	1
Parvizi, J	1
Kępa, K	1
Krzych, Ł	1
Krejca, M	1
Kowalewski, M	1
Pawliszak, W	1
Zaborowska, K	1
Navarese, EP	1
Szwed, KA	1
Kowalkowska, ME	1
Kowalewski, J	1
Borkowska, A	1
Anisimowicz, L	1
Westberg, M	1
Frihagen, F	1
Brun, OC	1
Figved, W	1
Grøgaard, B	1
Valland, H	1
Wangen, H	1
Snorrason, F	1
Lazar, HL	1
Buijs, EF	1
Theunisse, HJ	1
Mulder, JJ	1
van den Hoogen, FJ	1
Offeciers, EF	1
Zarowski, AJ	1
Mylanus, EA	1
Dineen, SP	1
Pham, TH	1
Murray, BW	1
Parker, BJ	1
Hartless, K	1
Anthony, T	1
Huerta, S	1
Musters, GD	1
Burger, JW	1
Buskens, CJ	1
Bemelman, WA	1
Tanis, PJ	1
Oller, I	1
Ruiz-Tovar, J	4
Cansado, P	1
Zubiaga, L	2
Calpena, R	3
Aeng, ES	1
Shalansky, KF	1
Lau, TT	1
Zalunardo, N	1
Li, G	1
Bowie, WR	1
Duncan, CP	1
Gbolahan, OO	1
Ogunmuyiwa, SA	1
Osinaike, BB	1
Llavero, C	3
Gamallo, C	1
Santos, J	2
Arroyo, A	2
Lopez, A	1
Candela, F	2
Beckman, JM	1
Amankwah, EK	1
Tetreault, LL	1
Perlman, SA	1
Tuite, GF	1
Reul, M	1
Nijs, S	1
Bosco, JA	1
Catanzano, AJ	1
Stachel, AG	1
Phillips, MS	1
Zietzschmann, S	1
Nguyen, AL	1
Pronk, AA	1
Furnée, EJ	1
Pronk, A	1
Davids, PH	1
Smakman, N	1
Lawing, CR	1
Lin, FC	1
Dahners, LE	2
Tucker, A	1
Henderson, L	1
Moffatt, R	1
Abela, R	1
Troughton, J	1
McMullan, R	1
Wilson, A	1
Lv, YF	1
Wang, J	1

Trial	Phase	Enrollment	Study Type	Start Date	Status
Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial[NCT05421741]	Phase 4	484 participants (Anticipated)	Interventional	2023-05-15	Recruiting
Topical Gentamicin and Vancomycin for Surgical Site Infection Prophylaxis in Patients Undergoing High-Risk Vascular Surgery[NCT04238923]	Phase 2/Phase 3	356 participants (Anticipated)	Interventional	2020-05-01	Not yet recruiting
Antibiotic Elution Profile and Outcomes in the Treatment of Prosthetic Joint Infections of the Knee[NCT06023238]		10 participants (Anticipated)	Observational	2023-06-05	Recruiting
Local Gentamicin Application to Reduce Postoperative Infection Rate in Hemiarthroplasty After Fracture of the Proximal Femur: a Randomized Controlled Trial[NCT01287780]	Phase 3	800 participants (Actual)	Interventional	2011-01-31	Completed
Developing Evidence of Effectiveness for Adjuvant Interventions Designed to Minimize Surgical Site Infections[NCT01153191]		120 participants (Anticipated)	Interventional	2010-08-31	Enrolling by invitation
PROTOP: Study of the Efficacy of Topical Antibiotherapy in the Prophylaxis of Incisional Surgical Localization Infection in Colorectal Surgery[NCT03574090]	Phase 4	268 participants (Actual)	Interventional	2020-10-20	Completed
Effect of Gentamicin Versus Clindamycin Versus Normal Saline Lavage of the Axillary Surgical Bed After Lymph Node Dissection on Drainage Discharge Volume[NCT02314806]	Phase 3	51 participants (Actual)	Interventional	2013-01-31	Completed
Paediatric Surgery Across Sub-Saharan Africa: A Multi-Centre Prospective Cohort Study[NCT03185637]		1,407 participants (Actual)	Observational [Patient Registry]	2016-10-01	Completed
Is Topical Antibiotic Prophylaxis Effective in Lichtenstein Hernia Repair: a Comparison Study[NCT01273818]	Phase 4	276 participants (Actual)	Interventional	2011-01-31	Completed
One Stage Versus Two Stage For Periprosthetic Hip And Knee Infection[NCT02734134]		343 participants (Actual)	Interventional	2016-05-18	Active, not recruiting
Local Application of Collagen-Gentamicin in Addition to Fixation of the Sternum With Extra Sternal Wires for Prevention of Sternal Wound Infection in Cardiac Surgery[NCT00484055]		1,358 participants (Actual)	Interventional	2007-01-31	Completed
A Randomized, Controlled, Phase 3 Study of Gentamicin-Collagen Sponge in Cardiac Surgical Subjects at Higher Risk for Sternal Wound Infection[NCT00600483]	Phase 3	1,502 participants (Actual)	Interventional	2007-12-31	Completed
A Randomized, Controlled, Phase 3 Study of Gentamicin-Collagen Sponge in General Surgical Subjects at Higher Risk for Surgical Wound Infection[NCT00600925]	Phase 3	602 participants (Actual)	Interventional	2008-01-31	Completed
Application of Antibiotic Loaded Calcium Sulfate as Prophylaxis for Patients With Non Modifiable Risk Factors for Periprosthetic Joint Infections[NCT03976466]	Phase 4	87 participants (Actual)	Interventional	2019-05-22	Completed
Effect of Peritoneal Lavage With Clindamycin-gentamicin Solution on Infection in Elective Surgery[NCT01378832]	Phase 3	102 participants (Actual)	Interventional	2010-01-31	Completed
A Novel Wound Retractor Combining Continuous Irrigation and Barrier Protection Reduces Incisional Contamination and Surgical Site Infection in Colorectal Surgery[NCT03816995]		702 participants (Anticipated)	Interventional	2019-02-12	Recruiting
A Phase 1, Open-Label, Single-Dose Study to Evaluate the Pharmacokinetics of a Single 3 Gram Dose of Cefazolin in Adult Subjects Weighing >= 120 kg Scheduled for Surgery[NCT05205486]	Phase 1	12 participants (Actual)	Interventional	2022-04-05	Completed
A Randomized, Controlled, Phase 4 Study of Sternal Plating (Rapid Sternal Closure System, KLS Martin L.P.) in Cardiac Surgical Subjects at Higher Risk for Sternal Wound Complications.[NCT00638014]	Phase 4	51 participants (Actual)	Interventional	2008-03-31	Completed
Prospective, Randomized, Double-blind Comparison of 5 % Against 1.25 % Povidone-iodine Solution as Preoperative Antisepsis for Strabismus Surgery in Young Children[NCT00461656]	Phase 4	70 participants (Actual)	Interventional	2009-09-30	Completed
Aspiration or Surgical Drainage of Perianal Abscess. A Randomized Controlled Clinical Study[NCT02585141]		111 participants (Actual)	Interventional	2015-10-31	Completed
Prospective, Randomized Study of the Utilization of Antibiotics and Drains in Spinal Surgery[NCT01608854]		539 participants (Actual)	Observational	2008-11-30	Completed
Randomized Control Trial of Vancomycin Powder Following Posterior Instrumented Spinal Surgery for Trauma[NCT01977989]	Phase 4	140 participants (Anticipated)	Interventional	2013-10-31	Enrolling by invitation
Contribution of Fast Molecular Bacterial Identification by Real-time PCR in Managing of Postoperative Acute Endophthalmitis[NCT02850653]		150 participants (Anticipated)	Interventional	2007-11-30	Recruiting
Use of Collatamp G Antibiotic Impregnated Sponges in the Treatment of Peri-prosthetic Total Joint Infections[NCT01667874]	Phase 3	17 participants (Actual)	Interventional	2013-01-31	Terminated (stopped due to Difficulty in recruiting patients for the study)
ERAS Lazio Network Clinical Registry[NCT03353311]		1,000 participants (Actual)	Observational [Patient Registry]	2014-09-01	Completed
Collagen-Gentamicin Implant in the Treatment of Contaminated Surgical Abdominal Wounds - A Randomized Controlled Trial[NCT00977405]	Phase 2	70 participants (Anticipated)	Interventional	2009-09-30	Terminated
Scaling Out and Scaling Up the Systems Analysis and Improvement Approach to Optimize the Hypertension Diagnosis and Care Cascade for HIV-infected Individuals[NCT05002322]		18 participants (Anticipated)	Interventional	2023-02-14	Recruiting
Secondary Intention Wound Healing, in Patients Subjected to Surgical Resection of Pilonidal Cyst, Using Alginate Dressings With Silver and High-G Cellulose, Compared to the Use of Simple Gauze Dressings: Examination of the Quality of Life[NCT03757572]		65 participants (Actual)	Interventional	2018-12-25	Terminated (stopped due to Early termination due to COVID-19 pandemic. Suspension of elective case operations. Decreased recruitment rate. Inability to reach the estimated sample size.)
The Effect of Negative Pressure Wound Therapy on Wound Healing in Major Amputations[NCT04618406]		160 participants (Anticipated)	Interventional	2021-11-01	Recruiting
Comparative Effectiveness and Cost-Benefit Analysis of Vancomycin Powder in High Risk Spine Surgery Patients[NCT01566422]		0 participants (Actual)	Interventional	2012-06-30	Withdrawn (stopped due to unable to enroll any participants)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Patients were examined on postoperative 30 days for the presence of surgical site infection. (NCT01273818)
Timeframe: within the 30 days after surgery

ASEPSIS Score

Intervention	infections (Number)
Topical Gentamicin	1
Cefazolin IV	3
Topical and iv	0

ASEPSIS Score through 90 days postoperative - To compare antibiotic regimens for their effectiveness in preventing or treating wound sepsis, well-defined criteria for outcome are needed. A method of assessing wound healing has been devised that defines carefully the characteristics to be considered and how they are to be awarded points. Objective criteria are also included in the assessment. Points are given for the need for Additional treatment, the presence of Serous discharge, Erythema, Purulent exudate, and Separation of the deep tissues, the Isolation of bacteria, and the duration of inpatient Stay (ASEPSIS). The higher the points the worse outcome. Maximum Points would be 60. Minimum points would be 0 (NCT00600483)
Timeframe: 90 days post cardiac surgery

Number of Participants With Surgical Wound Infections From Surgery Through Post-operative Day 90

Intervention	score on a scale (Mean)
Gentamicin Group	1.9
Control Group	2.0

Efficacy will be evaluated by a comparison between the 2 study groups of the incidence of surgical wound infections that occur within the period from surgery through postop day 90. (NCT00600483)
Timeframe: 90 days post cardiac surgery

Proportion of Patients With Deep Surgical Wound Infections Based on Centers for Disease Control Criteria Adjudicated by an Independent Blinded Committee.

Proportion of Patients With Superficial Surgical Wound Infections Based on Centers for Disease Control Criteria Adjudicated by an Independent Blinded Committee.

Rehospitalization for Sternal Wound Infection

Intervention	Participants (Count of Participants)
Gentamicin Group	63
Control Group	65

Intervention	Participants (Count of Participants)
Gentamicin Group	14
Control Group	19

Intervention	Participants (Count of Participants)
Gentamicin Group	49
Control Group	46

Rehospitalization for Sternal Wound Infection - within 90 days postoperatively. (NCT00600483)
Timeframe: 90 days post cardiac surgery

Surgically Treated Surgical Wound Infection Postoperative Day 90

Intervention	Participants (Count of Participants)
Gentamicin Group	23
Control Group	24

Proportion of patients with surgically treated surgical wound infection adjudicated by an independent blinded committee. (NCT00600483)
Timeframe: 90 days post cardiac surgery

Number of Participants Positive for Each Pathogen Culture

Intervention	Participants (Count of Participants)
Gentamicin Group	25
Control Group	37

Analysis associated with Microbial Pathogens in Adjudicated 90 Day SWI Subjects ME within Per Protocol Population. Any Microbial Pathogens Detected in SWI (ME) (NCT00600483)
Timeframe: 90 days post cardiac surgery

Number of Participants Who Had Superficial Incisional Surgical Wound Infection

Intervention	participants (Number)
	Acinetobacter calcoaceticus	Coagulase-neg staphylococci	Enterobacter cloacae	Enterococcus faecalis	Escherichia coli	Group B species streptococcus	Klebsiella pneumoniae	Klebsiella spp	Methicillin-resistant SA	Methicillin-sensitive SA	Other Specify 1	Proteus mirabilis	Providencia stuartii	Pseudomonas aeruginosa	Serratia marcescens	Staphylococcus aureus	Staphylococcus capitis	Staphylococcus epidermidis	Staphylococcus hominis	Staphylococcus lugdunensis	Staphylococcus xylosus	Streptococcus agalactiae
Control Group	0	2	1	1	3	0	2	2	1	2	3	5	0	3	4	6	0	7	1	1	1	0
Gentamicin Group	1	0	2	1	3	1	0	1	2	6	3	4	1	3	2	5	1	2	0	0	0	1

Number of Participants who had superficial incisional surgical wound infection, based on CDC criteria adjudicated by an independent blinded committee (NCT00600925)
Timeframe: assessed at Postop Day 1, 2, 3, 7, 30 & 60

Number of Participants Who Were Rehospitalized for Surgical Wound Infection Within 60 Days Post-operatively

Intervention	Participants (Count of Participants)
Gentamicin Group	61
Control	41

The effect of the gentamicin-collagen sponge on rehospitalization for surgical wound infection. (NCT00600925)
Timeframe: Through 60 days after surgery

Number of Participants With Surgical Wound Infections From Surgery Through Post-operative Day 60

Intervention	Participants (Count of Participants)
Gentamicin Group	21
Control	13

Primarily, efficacy will be evaluated by a comparison between the 2 study groups of the incidence of surgical wound infections (involving the laparotomy incision) that occur within the period from surgery through postop day 60. (NCT00600925)
Timeframe: assessed at Postop Day 1, 2, 3, 7, 30 & 60

The Effect of the Gentamicin-collagen Sponge on Length of Hospital Stay Postoperatively.

The Effect of the Gentamicin-collagen Sponge on the ASEPSIS Score

Intervention	Participants (Count of Participants)
Gentamicin Group	90
Control	63

Intervention	days (Mean)
Gentamicin Group	7.5
Control	7.3

Mean (SD) ASEPSIS Score Through 60 Days Postoperatively - brief assessment of surgical wound on post-operative Days 3, 4, 5, 6, and 7 (or discharge if earlier) and then questionnaire/phone call on post-operative Days 30 and 60. Score from each time point is added up and the mean score is reported. Used to compare antibiotic regimens for their effectiveness in preventing or treating wound sepsis, well-defined criteria for outcome are needed. A method of assessing wound healing has been devised that defines carefully the characteristics to be considered and how they are to be awarded points. Objective criteria are also included in the assessment. Points are given for the need for Additional treatment, the presence of Serous discharge, Erythema, Purulent exudate, and Separation of the deep tissues, the Isolation of bacteria, and the duration of inpatient Stay (ASEPSIS). The higher the points the worse outcome. Maximum Points would be 60. Minimum points would be 0 (NCT00600925)
Timeframe: Days 3, 4, 5, 6, and 7 (or discharge if earlier) and then questionnaire/phone call on post-operative Days 30 and 60.

The Effect of the Gentamicin-collagen Sponge on the Proportion of Patients With Deep Incisional Surgical Wound Infection

Intervention	score on a scale (Mean)
Gentamicin Group	6.1
Control	5.2

The proportion of subjects who had deep incisional SWI, based on Centers for Disease Control and Prevention (CDC) criteria adjudicated by an independent blinded committee (NCT00600925)
Timeframe: assessed at Postop Day 1, 2, 3, 7, 30 & 60

Length of Stay as an Indicator of the Hospital Economic Burden

Intervention	Participants (Count of Participants)
Gentamicin Group	25
Control	18

The length of stay is an important indicator of efficiency and hospital economic burden. The reduction in number of hospitalization days results in lower risk of infection and less medication side effects and decreased need of hospital supplies. The difference in the average days of hospitalization between both groups indirectly represents the economic cost spent by the hospital. (NCT03976466)
Timeframe: Surgical procedure day to hospital discharge.

Number of Participants With Sternal Wound Infection or Sternal Instability/Non-union

Intervention	Days (Mean)
Control Group	15.25
Calcium Sulfate Study Group	4.6

The Data and Safety Monitoring Board reviewed source documents for all cases with possible sternal wound infection and sternal instability or non-union and made a determination as to the presence of these complications. (NCT00638014)
Timeframe: Up to 180 days

Percentage Change of Preoperative Incentive Spirometry (IS) Volume Achieved

Intervention	Participants (Number)
Conventional Wires Only	1
Talon	1

Maximum incentive spirometry volume was measured at baseline (prior to surgery) and daily from postoperative day 1 through postoperative day 7 (or discharge if earlier) using a Coach 2 incentive spirometer with one way valve (Coach 2 model # 22-4000, Smiths Medical, Keene, NH). (NCT00638014)
Timeframe: Baseline, Maximum value during postoperatively days 1 thru 7

Article	Year
Comprehensive meta-analysis of antibiotic-impregnated bone cement versus plain bone cement in primary total knee arthroplasty for preventing periprosthetic joint infection. Chinese journal of traumatology = Zhonghua chuang shang za zhi, 2022, Volume: 25, Issue:6 Topics: Anti-Bacterial Agents; Arthritis, Infectious; Arthroplasty, Replacement, Knee; Bone Cements; Gentami	2022
Perioperative prophylaxis for surgical site infections in pediatric spinal surgery: a systematic review and network meta-analysis. Journal of neurosurgery. Pediatrics, 2023, 01-01, Volume: 31, Issue:1 Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Child; Gentamicins; Humans; Network Meta-	2023
A meta-analysis examined the effect of topical nursing application of antimicrobial as a prophylaxis for the stoppage of surgical wound infection in colorectal surgery. International wound journal, 2023, Volume: 20, Issue:6 Topics: Anti-Bacterial Agents; Anti-Infective Agents; Collagen; Colorectal Surgery; Gentamicins; Humans; Oin	2023
Gentamicin-Coated Tibia Nail in Fractures and Nonunion to Reduce Fracture-Related Infections: A Systematic Review. Molecules (Basel, Switzerland), 2020, Nov-23, Volume: 25, Issue:22 Topics: Animals; Bone Nails; Coated Materials, Biocompatible; Gentamicins; Humans; Osteomyelitis; Postoperat	2020
Does routine topical antimicrobial administration prevent sternal wound infection after cardiac surgery? Interactive cardiovascular and thoracic surgery, 2021, 04-08, Volume: 32, Issue:3 Topics: Administration, Topical; Anti-Infective Agents; Cardiac Surgical Procedures; Gentamicins; Humans; Me	2021
Gentamicin-collagen implants to reduce surgical site infection: systematic review and meta-analysis of randomized trials. Annals of surgery, 2013, Volume: 258, Issue:1 Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Collagen; Drug Implants; Gentamicins; Humans; Randomi	2013
[Rational approach of antibioprophylaxis: systematic review in ENT cancer surgery]. Annales francaises d'anesthesie et de reanimation, 2013, Volume: 32, Issue:5 Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Antibiotic Prophylaxis; Clinda	2013
Gentamicin/collagen sponge use may reduce the risk of surgical site infections for patients undergoing cardiac operations: a meta-analysis. Surgical infections, 2014, Volume: 15, Issue:3 Topics: Anti-Bacterial Agents; Biostatistics; Collagen; Gentamicins; Humans; Randomized Controlled Trials as	2014
Role of topical application of gentamicin containing collagen implants in cardiac surgery. Journal of cardiothoracic surgery, 2014, Jul-08, Volume: 9 Topics: Administration, Topical; Anti-Bacterial Agents; Cardiac Surgical Procedures; Collagen; Gentamicins;	2014
Antibiotic-loaded bone cement and periprosthetic joint infection. Journal of long-term effects of medical implants, 2014, Volume: 24, Issue:2-3 Topics: Anti-Bacterial Agents; Arthroplasty, Replacement; Bone Cements; Diffusion; Gentamicins; Humans; Join	2014
Gentamicin-collagen sponge reduces the risk of sternal wound infections after heart surgery: Meta-analysis. The Journal of thoracic and cardiovascular surgery, 2015, Volume: 149, Issue:6 Topics: Anti-Bacterial Agents; Cardiac Surgical Procedures; Chi-Square Distribution; Drug Carriers; Gentamic	2015
Local Application of Gentamicin in the Prophylaxis of Perineal Wound Infection After Abdominoperineal Resection: A Systematic Review. World journal of surgery, 2015, Volume: 39, Issue:11 Topics: Abdomen; Anti-Bacterial Agents; Antibiotic Prophylaxis; Gentamicins; Humans; Perineum; Rectal Neopla	2015
The use of gentamicin-coated nails in complex open tibia fracture and revision cases: A retrospective analysis of a single centre case series and review of the literature. Injury, 2015, Volume: 46, Issue:12 Topics: Adult; Aged; Anti-Bacterial Agents; Belgium; Bone Nails; Female; Fracture Fixation, Intramedullary;	2015
Local administration of gentamicin collagen sponge in surgical excision of sacrococcygeal pilonidal sinus disease: a systematic review and meta-analysis of the literature. Techniques in coloproctology, 2016, Volume: 20, Issue:2 Topics: Administration, Topical; Anti-Bacterial Agents; Collagen; Follow-Up Studies; Gentamicins; Humans; Pi	2016
Meta-analysis of local gentamicin for prophylaxis of surgical site infections in colorectal surgery. International journal of colorectal disease, 2016, Volume: 31, Issue:2 Topics: Administration, Topical; Anti-Bacterial Agents; Colonic Diseases; Colorectal Neoplasms; Gentamicins;	2016
Gentamicin-Collagen Sponges for the Prevention of Surgical Site Infections: A Meta-Analysis of Randomized Controlled Trials. Surgical infections, 2016, Volume: 17, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Collagen; Gentamicins; Humans; Middle Aged; Randomized Controlled Tr	2016
[Treatment of periprosthetic infections]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 2016, Volume: 87, Issue:10 Topics: Algorithms; Biofilms; Chronic Disease; Combined Modality Therapy; Debridement; Gentamicins; Humans;	2016
Local application of gentamicin collagen implants in the prophylaxis of surgical site infections following gastrointestinal surgery: a review of clinical experience. Techniques in coloproctology, 2010, Volume: 14, Issue:4 Topics: Absorbable Implants; Antibiotic Prophylaxis; Collagen; Gastrointestinal Tract; Gentamicins; Humans;	2010
Use of gentamicin-collagen sponges in closure of sternal wounds in cardiothoracic surgery to reduce wound infections. Interactive cardiovascular and thoracic surgery, 2012, Volume: 14, Issue:4 Topics: Anti-Bacterial Agents; Benchmarking; Cardiac Surgical Procedures; Collagen; Drug Implants; Drug Resi	2012
Effectiveness of a gentamicin impregnated collagen sponge on reducing sternal wound infections following cardiac surgery: a meta-analysis of randomised controlled trials. Annals of the Royal College of Surgeons of England, 2012, Volume: 94, Issue:4 Topics: Anti-Bacterial Agents; Cardiac Surgical Procedures; Collagen; Gentamicins; Humans; Randomized Contro	2012
Local application of gentamicin-containing collagen implant in the prophylaxis and treatment of surgical site infection following vascular surgery. International journal of surgery (London, England), 2012, Volume: 10 Suppl 1 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacteria; Cohort Stud	2012
Local application of gentamicin-containing collagen implant in the prophylaxis of surgical site infection following gastrointestinal surgery. International journal of surgery (London, England), 2012, Volume: 10 Suppl 1 Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Cohort Studies; Collagen Type I; Digestive System Sur	2012
Local application of gentamicin-containing collagen implant in the prophylaxis and treatment of surgical site infection in orthopaedic surgery. International journal of surgery (London, England), 2012, Volume: 10 Suppl 1 Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Clinical Trials as Topic; Cohort Studies; Collagen Ty	2012
Gentamicin collagen sponges for the prevention of sternal wound infection: a meta-analysis of randomized controlled trials. The Journal of thoracic and cardiovascular surgery, 2012, Volume: 144, Issue:5 Topics: Anti-Bacterial Agents; Cardiac Surgical Procedures; Chi-Square Distribution; Collagen; Evidence-Base	2012
Prevention of surgical wound infection: prophylactic antibiotics in colorectal surgery. Journal of wound care, 2005, Volume: 14, Issue:5 Topics: Administration, Topical; Antibiotic Prophylaxis; Colorectal Surgery; Drug Therapy, Combination; Fema	2005
Successful management of orbital cellulitis and temporary visual loss after blepharoplasty. Plastic and reconstructive surgery, 2006, Volume: 118, Issue:3 Topics: Abscess; Adult; Anti-Bacterial Agents; Blepharoplasty; Blindness; Brimonidine Tartrate; Cavernous Si	2006
Assessing cost effectiveness of antimicrobial treatment: monotherapy compared with combination therapy. The European journal of surgery. Supplement. : = Acta chirurgica. Supplement, 1994, Issue:573 Topics: Anti-Bacterial Agents; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Gentamicins; Hu	1994
[Use of mini-septopal in trauma surgery of the hand. Experimental and clinical studies]. Polimery w medycynie, 1996, Volume: 26, Issue:1-2 Topics: Animals; Antibiotic Prophylaxis; Drug Implants; Drug Resistance, Microbial; Gentamicins; Hand Injuri	1996
Local treatment of bone and soft tissue infections with the collagen-gentamicin sponge. The European journal of surgery. Supplement. : = Acta chirurgica. Supplement, 1997, Issue:578 Topics: Animals; Anti-Bacterial Agents; Collagen; Controlled Clinical Trials as Topic; Disease Models, Anima	1997
Applications of local antibiotic therapy. The European journal of surgery. Supplement. : = Acta chirurgica. Supplement, 1997, Issue:578 Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Collagen; Controlled Clinical Trials as Topic; Delaye	1997
Antimicrobial prophylaxis in colorectal surgery: a systematic review of randomized controlled trials. The British journal of surgery, 1998, Volume: 85, Issue:9 Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Choice Behavior; Colon; Drug Therapy, Com	1998
[Use of the antibiotics in prevention of postoperative infections (review of the literature)]. Khirurgiia, 1978, Issue:8 Topics: Anti-Bacterial Agents; Bacterial Infections; Cardiac Surgical Procedures; Cephalosporins; Erythromyc	1978
Prophylactic antibiotics for total hip arthroplasty--the significance of Staphylococcus epidermidis. The Journal of antimicrobial chemotherapy, 1979, Volume: 5, Issue:5 Topics: Animals; Anti-Bacterial Agents; Cephalosporins; Drug Synergism; Gentamicins; Hip Prosthesis; Humans;	1979
Antibiotic prophylaxis in acute non-perforated appendicitis in children: single dose of metronidazole and gentamicin. Journal of the Royal College of Surgeons of Edinburgh, 1992, Volume: 37, Issue:2 Topics: Acute Disease; Adolescent; Appendicitis; Child; Child, Preschool; Female; Gentamicins; Humans; Male;	1992
Pseudomonas aeruginosa infections. CRC critical reviews in clinical laboratory sciences, 1972, Volume: 3, Issue:3 Topics: Animals; Antibodies, Bacterial; Antineoplastic Agents; Arthritis, Infectious; Bone Diseases; Burns;	1972

Article	Year
Application of local gentamicin in the treatment of deep sternal wound infection: a randomized controlled trial. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2022, 05-02, Volume: 61, Issue:5 Topics: Anti-Bacterial Agents; Cardiac Surgical Procedures; Gentamicins; Humans; Retrospective Studies; Ster	2022
Topical Vancomycin and Risk of Sternal Wound Infections: A Double-Blind Randomized Controlled Trial. The Annals of thoracic surgery, 2022, Volume: 114, Issue:5 Topics: Anti-Bacterial Agents; Coagulase; Gentamicins; Humans; Sternum; Surgical Wound Infection; Vancomycin	2022
Prevention of Surgical Site Infection Following Open Spine Surgery: The Efficacy of Intraoperative Wound Irrigation with Normal Saline Containing Gentamicin Versus Dilute Povidone-Iodine. World neurosurgery, 2023, Volume: 173 Topics: Anti-Infective Agents, Local; Gentamicins; Humans; Povidone-Iodine; Prospective Studies; Saline Solu	2023
Gentamicin Containing Collagen Implants and Groin Wound Infections in Vascular Surgery: A Prospective Randomised Controlled Multicentre Trial. European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery, 2020, Volume: 59, Issue:4 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Aortic Aneurysm, Abdominal;	2020
A randomized controlled trial on irrigation of open appendectomy wound with gentamicin- saline solution versus saline solution for prevention of surgical site infection. International journal of surgery (London, England), 2020, Volume: 81 Topics: Acute Disease; Adolescent; Adult; Appendectomy; Appendicitis; Double-Blind Method; Female; Gentamici	2020
A prospective comparison of four methods for preventing pacemaker pocket infections. Artificial organs, 2021, Volume: 45, Issue:4 Topics: Aged; Anti-Bacterial Agents; Batroxobin; Female; Gentamicins; Humans; Male; Pacemaker, Artificial; P	2021
A prospective multicentre randomized placebo-controlled superiority trial in patients with suspected bacterial endophthalmitis after cataract surgery on the adjuvant use of intravitreal dexamethasone to intravitreal antibiotics. Acta ophthalmologica, 2018, Volume: 96, Issue:4 Topics: Aged; Anti-Bacterial Agents; Cataract Extraction; Dexamethasone; Endophthalmitis; Eye Infections, Ba	2018
Comparing a combination of penicillin G and gentamicin to a combination of clindamycin and amikacin as prophylactic antibiotic regimens in prevention of clean contaminated wound infections in cancer surgery. Journal of the Egyptian National Cancer Institute, 2013, Volume: 25, Issue:1 Topics: Adult; Amikacin; Anti-Bacterial Agents; Antibiotic Prophylaxis; Clindamycin; Colorectal Neoplasms; D	2013
A preformed antibiotic-loaded spacer for treatment for septic arthritis of the shoulder. Musculoskeletal surgery, 2014, Volume: 98, Issue:1 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Arthritis, Infectious; Arthritis, Rheumatoid; Arthro	2014
Single dose of gentamicin in combination with metronidazole versus multiple doses for prevention of post-caesarean infection at Bugando Medical Centre in Mwanza, Tanzania: a randomized, equivalence, controlled trial. BMC pregnancy and childbirth, 2013, May-31, Volume: 13 Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Antibiotic Prophylaxis; Cesarean Section; Drug	2013
Ertapenem versus standard triple antibiotic therapy for the treatment of perforated appendicitis in pediatric patients: a prospective randomized trial. European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 2014, Volume: 24, Issue:5 Topics: Adolescent; Ampicillin; Anti-Bacterial Agents; Appendectomy; Appendicitis; beta-Lactams; Child; Chil	2014
Surgical site infections following short-term radiotherapy and total mesorectal excision: results of a randomized study examining the role of gentamicin collagen implant in rectal cancer surgery. Techniques in coloproctology, 2014, Volume: 18, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Anastomotic Leak; Anti-Bacterial Agents; Collagen; Combined Modality	2014
Subcutaneous application of gentamicin collagen implants as prophylaxis of surgical site infections in laparoscopic colorectal surgery: a randomized, double-blinded, three-arm trial. Langenbeck's archives of surgery, 2015, Volume: 400, Issue:1 Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Collagen; Colon; Digestive System Surgical Proc	2015
Collagen implant with gentamicin sulphate reduces surgical site infection in vascular surgery: a prospective cohort study. International journal of surgery (London, England), 2014, Volume: 12, Issue:10 Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Collagen; Drug Implants; Female; Gentamicins; H	2014
Effectiveness of gentamicin-containing collagen sponges for prevention of surgical site infection after hip arthroplasty: a multicenter randomized trial. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2015, Jun-15, Volume: 60, Issue:12 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Arthroplasty, Replacement, H	2015
Feasibility of subcutaneous gentamicin and pressurized irrigation as adjuvant strategies to reduce surgical site infection in colorectal surgery: results of a pilot study. The American surgeon, 2015, Volume: 81, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Anti-Bacterial Agents; Body Mass Index; Colore	2015
Effect of Lavage with Gentamicin vs. Clindamycin vs. Physiologic Saline on Drainage Discharge of the Axillary Surgical Bed after Lymph Node Dissection. Surgical infections, 2015, Volume: 16, Issue:6 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Clindamycin; Drainage; Exudates and Transudat	2015
Randomized Controlled Trial comparing Dressing and No Dressing of Surgical Wound after Cleft Lip Repair. The journal of contemporary dental practice, 2015, 07-01, Volume: 16, Issue:7 Topics: Anti-Bacterial Agents; Bandages; Cicatrix; Cleft Lip; Esthetics; Female; Follow-Up Studies; Gentamic	2015
Effect of Peritoneal Lavage with Clindamycin-Gentamicin Solution during Elective Colorectal Cancer Surgery on the Oncologic Outcome. Surgical infections, 2016, Volume: 17, Issue:1 Topics: Adult; Aged; Anti-Bacterial Agents; Clindamycin; Colorectal Neoplasms; Female; Gentamicins; Humans;	2016
Effect of Peritoneal Lavage with Clindamycin-Gentamicin Solution on Post-Operative Pain and Analytic Acute-Phase Reactants after Laparoscopic Sleeve Gastrectomy. Surgical infections, 2016, Volume: 17, Issue:3 Topics: Acute-Phase Proteins; Adult; Anti-Bacterial Agents; Ascitic Fluid; Biomarkers; Clindamycin; Female;	2016
Efficacy of postoperative antibiotic injection in and around ventriculoperitoneal shunt in reduction of shunt infection: A randomized controlled trial. Clinical neurology and neurosurgery, 2016, Volume: 143 Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Catheters, Indwelling; Female; Follow-Up Studies; Gen	2016
Prevention of surgical site sternal infections in cardiac surgery: a two-centre prospective randomized controlled study. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2017, Volume: 51, Issue:1 Topics: Administration, Topical; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Proce	2017
A randomized, blinded, multicenter trial of a gentamicin vancomycin gel (DFA-02) in patients undergoing abdominal surgery. American journal of surgery, 2017, Volume: 213, Issue:6 Topics: Abdominal Wound Closure Techniques; Adult; Aged; Anti-Bacterial Agents; Digestive System Surgical Pr	2017
The role of preoperative antibiotics in the prevention of wound infection after day case surgery for inguinal hernia in children in Ile Ife, Nigeria. Pediatric surgery international, 2008, Volume: 24, Issue:10 Topics: Adolescent; Ambulatory Surgical Procedures; Anti-Bacterial Agents; Antibiotic Prophylaxis; Child; Ch	2008
Comparison of ceftriaxone versus triple drug regimen in the prevention of cesarean section infectious morbidities. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2008, Volume: 21, Issue:9 Topics: Adult; Ampicillin; Anti-Bacterial Agents; Antibiotic Prophylaxis; Ceftriaxone; Cesarean Section; Clo	2008
[Prospective study comparing the incidence of wound infection following appendectomy for acute appendicitis in children: conventional treatment versus using reabsorbable antibacterial suture or gentamicin-impregnated collagen fleeces]. Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica, 2008, Volume: 21, Issue:4 Topics: Adolescent; Anti-Bacterial Agents; Appendectomy; Appendicitis; Bandages; Child; Child, Preschool; Co	2008
Local antibiotics are equivalent to intravenous antibiotics in the prevention of superficial wound infection in inguinal hernioplasty. Asian journal of surgery, 2009, Volume: 32, Issue:1 Topics: Administration, Topical; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Female; Gentamicins; H	2009
Collagen-gentamicin implant for prevention of sternal wound infection; long-term follow-up of effectiveness. Interactive cardiovascular and thoracic surgery, 2009, Volume: 9, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Chemistry, Pharmaceut	2009
Effect of an implantable gentamicin-collagen sponge on sternal wound infections following cardiac surgery: a randomized trial. JAMA, 2010, Aug-18, Volume: 304, Issue:7 Topics: Aged; Anti-Bacterial Agents; Cardiac Surgical Procedures; Female; Gentamicins; Humans; Male; Middle	2010
Gentamicin-collagen sponge for infection prophylaxis in colorectal surgery. The New England journal of medicine, 2010, Sep-09, Volume: 363, Issue:11 Topics: Absorbable Implants; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Colectomy; Collagen; Color	2010
Gentamicin-collagen sponge for infection prophylaxis in colorectal surgery. The New England journal of medicine, 2010, Sep-09, Volume: 363, Issue:11 Topics: Absorbable Implants; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Colectomy; Collagen; Color	2010
Gentamicin-collagen sponge for infection prophylaxis in colorectal surgery. The New England journal of medicine, 2010, Sep-09, Volume: 363, Issue:11 Topics: Absorbable Implants; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Colectomy; Collagen; Color	2010
Gentamicin-collagen sponge for infection prophylaxis in colorectal surgery. The New England journal of medicine, 2010, Sep-09, Volume: 363, Issue:11 Topics: Absorbable Implants; Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Colectomy; Collagen; Color	2010
Gentamicin-collagen sponge reduces sternal wound complications after heart surgery: a controlled, prospectively randomized, double-blind study. The Journal of thoracic and cardiovascular surgery, 2012, Volume: 143, Issue:1 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cardiac Surgical Procedures; Collagen; Double	2012
Effect of peritoneal lavage with clindamycin-gentamicin solution on infections after elective colorectal cancer surgery. Journal of the American College of Surgeons, 2012, Volume: 214, Issue:2 Topics: Abdominal Abscess; Aged; Anti-Bacterial Agents; Clindamycin; Colonic Neoplasms; Digestive System Sur	2012
Effect of peritoneal lavage with clindamycin-gentamicin solution on infections after elective colorectal cancer surgery. Journal of the American College of Surgeons, 2012, Volume: 214, Issue:2 Topics: Abdominal Abscess; Aged; Anti-Bacterial Agents; Clindamycin; Colonic Neoplasms; Digestive System Sur	2012
Effect of peritoneal lavage with clindamycin-gentamicin solution on infections after elective colorectal cancer surgery. Journal of the American College of Surgeons, 2012, Volume: 214, Issue:2 Topics: Abdominal Abscess; Aged; Anti-Bacterial Agents; Clindamycin; Colonic Neoplasms; Digestive System Sur	2012
Effect of peritoneal lavage with clindamycin-gentamicin solution on infections after elective colorectal cancer surgery. Journal of the American College of Surgeons, 2012, Volume: 214, Issue:2 Topics: Abdominal Abscess; Aged; Anti-Bacterial Agents; Clindamycin; Colonic Neoplasms; Digestive System Sur	2012
Efficacy of single dose of gentamicin in combination with metronidazole versus multiple doses for prevention of post-caesarean infection: study protocol for a randomized controlled trial. Trials, 2012, Jun-21, Volume: 13 Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Cesarean Section; Drug Administration Schedule; Drug	2012
Effect of local gentamicin-collagen on perineal wound complications and cancer recurrence after abdominoperineal resection: a multicentre randomized controlled trial. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2013, Volume: 15, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Collagen; Drug Combinations; Female; Follow-U	2013
Comparison of two antimicrobial regimens on the prevalence of incisional infections after colic surgery. The Veterinary record, 2013, Mar-16, Volume: 172, Issue:11 Topics: Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Colic; Drug Administration Schedule; Female;	2013
Local antibiotic therapy in rectal cancer surgery. Polski przeglad chirurgiczny, 2012, Volume: 84, Issue:12 Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anastomosis, Surgical; Anti-Bacterial Agent	2012
Antibiotic pharmacodynamics in surgical prophylaxis: an association between intraoperative antibiotic concentrations and efficacy. Antimicrobial agents and chemotherapy, 2002, Volume: 46, Issue:9 Topics: Algorithms; Anti-Bacterial Agents; Antibiotic Prophylaxis; Area Under Curve; Colon; Double-Blind Met	2002
Antibiotic prophylaxis in surgery of the intervertebral disc. A comparison between gentamicin and cefuroxime. The Journal of bone and joint surgery. British volume, 2002, Volume: 84, Issue:7 Topics: Adult; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cefuroxime; Cephalosporins; Double-Blind Metho	2002
Efficacy and tolerance of a new gentamicin collagen fleece (Septocoll) after surgical treatment of a pilonidal sinus. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2003, Volume: 5, Issue:3 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Collagen; Female; Follow-Up Studies; Gentamicins; Hu	2003
Choice of antibiotics for infection prophylaxis in emergency cesarean sections in low-income countries: a cost-benefit study in Mozambique. Acta obstetricia et gynecologica Scandinavica, 2003, Volume: 82, Issue:7 Topics: Adult; Antibiotic Prophylaxis; Cesarean Section; Cost-Benefit Analysis; Drug Administration Schedule	2003
Prophylaxis of sternal wound infections with gentamicin-collagen implant: randomized controlled study in cardiac surgery. The Journal of hospital infection, 2005, Volume: 59, Issue:2 Topics: Analysis of Variance; Antibiotic Prophylaxis; Coronary Artery Bypass; Drug Implants; Female; Gentami	2005
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery, 2005, Volume: 79, Issue:1 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Pr	2005
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery, 2005, Volume: 79, Issue:1 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Pr	2005
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery, 2005, Volume: 79, Issue:1 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Pr	2005
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery, 2005, Volume: 79, Issue:1 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Pr	2005
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery, 2005, Volume: 79, Issue:1 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Pr	2005
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery, 2005, Volume: 79, Issue:1 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Pr	2005
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery, 2005, Volume: 79, Issue:1 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Pr	2005
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery, 2005, Volume: 79, Issue:1 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Pr	2005
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery, 2005, Volume: 79, Issue:1 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Pr	2005
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery, 2005, Volume: 79, Issue:1 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Pr	2005
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery, 2005, Volume: 79, Issue:1 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Pr	2005
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery, 2005, Volume: 79, Issue:1 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Pr	2005
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery, 2005, Volume: 79, Issue:1 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Pr	2005
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery, 2005, Volume: 79, Issue:1 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Pr	2005
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery, 2005, Volume: 79, Issue:1 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Pr	2005
Local gentamicin reduces sternal wound infections after cardiac surgery: a randomized controlled trial. The Annals of thoracic surgery, 2005, Volume: 79, Issue:1 Topics: Administration, Topical; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Pr	2005
Subcutaneous gentamycin implant to reduce wound infections after loop-ileostomy closure: a randomized, double-blind, placebo-controlled trial. Diseases of the colon and rectum, 2005, Volume: 48, Issue:11 Topics: Aged; Anti-Bacterial Agents; Antibiotic Prophylaxis; Double-Blind Method; Drug Implants; Female; Gen	2005
Cost effectiveness of local collagen-gentamicin as prophylaxis for sternal wound infections in different risk groups. Scandinavian cardiovascular journal : SCJ, 2006, Volume: 40, Issue:2 Topics: Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Procedures;	2006
Incidence, microbiological findings, and clinical presentation of sternal wound infections after cardiac surgery with and without local gentamicin prophylaxis. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2007, Volume: 26, Issue:2 Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Bacterial Infections; Cardiac Surgical Procedures; Ge	2007
Randomized clinical trial of surgical technique and local antibiotics for ingrowing toenail. The British journal of surgery, 2007, Volume: 94, Issue:3 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents, Local; Child; Drug Therapy, C	2007
Local collagen-gentamicin for prevention of sternal wound infections: the LOGIP trial. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2007, Volume: 115, Issue:9 Topics: Absorbable Implants; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Antibiotic Prophylaxis;	2007
Prevention of sternal wound infections with locally administered gentamicin. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica, 2007, Volume: 115, Issue:9 Topics: Absorbable Implants; Anti-Bacterial Agents; Antibiotic Prophylaxis; Cardiac Surgical Procedures; Col	2007
Surgical treatment of hidradenitis suppurativa with gentamicin sulfate: a prospective randomized study. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2008, Volume: 34, Issue:2 Topics: Administration, Topical; Adolescent; Adult; Anti-Bacterial Agents; Female; Follow-Up Studies; Gentam	2008
Failure of antimicrobial prophylaxis with cefoxitin, or metronidazole and gentamicin in colorectal surgery. Is mannitol to blame? The Journal of hospital infection, 1981, Volume: 2, Issue:2 Topics: Anti-Bacterial Agents; Cefoxitin; Colitis; Colon; Escherichia coli; Female; Gentamicins; Humans; Int	1981
Metronidazole need not be combined with an aminoglycoside when used for prophylaxis in elective colorectal surgery. The Journal of hospital infection, 1983, Volume: 4, Issue:1 Topics: Abscess; Aged; Colon; Drug Therapy, Combination; Female; Gentamicins; Humans; Male; Metronidazole; M	1983
Mezlocillin in serious surgical infections caused by carbenicillin-resistant bacteria. Infection, 1982, Volume: 10 Suppl 3 Topics: Adult; Aged; Bacteria; Bacterial Infections; Carbenicillin; Female; Gentamicins; Humans; Male; Mezlo	1982
Clinical comparison of cefotaxime versus the combination of gentamicin plus clindamycin in the treatment of peritonitis and similar polymicrobial soft-tissue surgical sepsis. Clinical therapeutics, 1981, Volume: 4 Suppl A Topics: Adolescent; Adult; Aged; Cefotaxime; Clindamycin; Clinical Trials as Topic; Costs and Cost Analysis;	1981
Clinical comparison of cefotaxime versus the combination of gentamicin plus clindamycin in the treatment of polymicrobial soft-tissue surgical sepsis. Clinical therapeutics, 1982, Volume: 5 Suppl A Topics: Adolescent; Adult; Aged; Cefotaxime; Clindamycin; Clinical Trials as Topic; Drug Therapy, Combinatio	1982
Third-generation cephalosporins for polymicrobial surgical sepsis. Archives of surgery (Chicago, Ill. : 1960), 1983, Volume: 118, Issue:2 Topics: Abscess; Adolescent; Adult; Aged; Bacteria; Bacterial Infections; Cefoperazone; Cefotaxime; Cephalos	1983
Antibiotic prophylaxis in large bowel surgery: results of a controlled clinical trial. Surgery, 1983, Volume: 93, Issue:1 Pt 2 Topics: Aged; Anti-Bacterial Agents; Clindamycin; Clinical Trials as Topic; Drug Therapy, Combination; Feces	1983
Antibiotic prophylaxis in acute appendicitis. Surgery, gynecology & obstetrics, 1983, Volume: 156, Issue:2 Topics: Acute Disease; Administration, Oral; Adolescent; Appendectomy; Appendicitis; Clinical Trials as Topi	1983
A comparison of intravenous cefoxitin and a combination of gentamicin and metronidazole as prophylaxis in colorectal surgery. Diseases of the colon and rectum, 1983, Volume: 26, Issue:10 Topics: Aged; Cefoxitin; Clinical Trials as Topic; Colon; Drug Therapy, Combination; Female; Gentamicins; Hu	1983
A comparative study of netilmicin-cefoxitin and gentamicin-cefoxitin in surgical patients with serious systemic infection. Clinical therapeutics, 1983, Volume: 5, Issue:5 Topics: Adolescent; Adult; Aged; Bacterial Infections; Bacteroides Infections; Cefoxitin; Clinical Trials as	1983
Antimicrobial prophylaxis for contaminated head and neck surgery. The Laryngoscope, 1984, Volume: 94, Issue:1 Topics: Anti-Bacterial Agents; Cefazolin; Clindamycin; Clinical Trials as Topic; Drug Therapy, Combination;	1984
A comparative study of cefamandole versus gentamicin plus clindamycin in the treatment of documented or suspected bacterial peritonitis. Surgery, gynecology & obstetrics, 1984, Volume: 158, Issue:1 Topics: Adolescent; Adult; Aged; Bacterial Infections; Cefamandole; Clindamycin; Clinical Trials as Topic; C	1984
Antibiotic prophylaxis in neurosurgery. A randomized controlled trial. Journal of neurosurgery, 1984, Volume: 60, Issue:4 Topics: Adult; Anti-Bacterial Agents; Clinical Trials as Topic; Gentamicins; Humans; Middle Aged; Random All	1984
Combined preoperative antibiotic therapy and intraoperative topical povidone-iodine. Reduction of wound sepsis following emergency appendectomy. Archives of surgery (Chicago, Ill. : 1960), 1984, Volume: 119, Issue:8 Topics: Administration, Topical; Adolescent; Adult; Appendectomy; Appendicitis; Clindamycin; Clinical Trials	1984
[Clinical studies on effect of netilmicin in surgery]. The Japanese journal of antibiotics, 1983, Volume: 36, Issue:5 Topics: Adolescent; Adult; Aged; Child; Clinical Trials as Topic; Enterococcus faecalis; Female; Gentamicins	1983
Audit of sepsis in operations for inflammatory bowel disease. Diseases of the colon and rectum, 1984, Volume: 27, Issue:9 Topics: Abscess; Adult; Colitis, Ulcerative; Crohn Disease; Female; Gentamicins; Humans; Male; Metronidazole	1984
Comparative study of netilmicin/tinidazole versus netilmicin/clindamycin in the treatment of severe abdominal infections. Scandinavian journal of infectious diseases, 1984, Volume: 16, Issue:3 Topics: Adolescent; Adult; Aged; Bacteria; Clindamycin; Drug Therapy, Combination; Female; Gentamicins; Huma	1984
[Experience with intravenous metronidazole administration in the preoperative care of surgery of the large intestine]. Zentralblatt fur Chirurgie, 1983, Volume: 108, Issue:20 Topics: Colon; Drug Therapy, Combination; Gentamicins; Humans; Infusions, Parenteral; Metronidazole; Premedi	1983
[Antibiotic prophylaxis in colorectal surgery: results of a randomized clinical study]. Helvetica chirurgica acta, 1982, Volume: 49, Issue:3-4 Topics: Anti-Bacterial Agents; Clindamycin; Clinical Trials as Topic; Colon; Drug Combinations; Gentamicins;	1982
Bacterial flora in relation to cataract extraction. V. Effects of topical antibiotics on the preoperative conjunctival flora. Acta ophthalmologica, 1980, Volume: 58, Issue:4 Topics: Adult; Aged; Anti-Bacterial Agents; Bacitracin; Bacteria; Bacterial Infections; Cataract Extraction;	1980
Antibiotic prophylaxis against wound infection in emergency abdominal surgery. Journal of the Royal College of Surgeons of Edinburgh, 1981, Volume: 26, Issue:4 Topics: Abdomen; Aged; Clindamycin; Clinical Trials as Topic; Emergencies; Female; Gentamicins; Humans; Midd	1981
Single-dose intraoperative antibiotic prophylaxis in emergency abdominal surgery. Archives of surgery (Chicago, Ill. : 1960), 1982, Volume: 117, Issue:2 Topics: Abdomen; Aged; Anti-Bacterial Agents; Clindamycin; Clinical Trials as Topic; Drug Therapy, Combinati	1982
Clinical trials of the efficacy and duration of antibacterial cover for elective resection in inflammatory bowel disease. The British journal of surgery, 1982, Volume: 69, Issue:4 Topics: Adult; Bacterial Infections; Clinical Trials as Topic; Colitis, Ulcerative; Crohn Disease; Double-Bl	1982
A double-blind, randomized comparison of clindamycin-gentamicin versus cefamandole for treatment of post-cesarean section endomyometritis. American journal of obstetrics and gynecology, 1982, Oct-01, Volume: 144, Issue:3 Topics: Adult; Cefamandole; Cephalosporins; Cesarean Section; Clindamycin; Double-Blind Method; Drug Resista	1982
Comparison of metronidazole with clindamycin-gentamycin combination in the prevention of infectious complications after elective colonic surgery. Annales chirurgiae et gynaecologiae, 1982, Volume: 71, Issue:6 Topics: Adolescent; Adult; Aged; Clindamycin; Colonic Diseases; Drug Therapy, Combination; Female; Gentamici	1982
Clinical comparison of antibiotic combinations in the treatment of peritonitis and related mixed aerobic-anaerobic surgical sepsis. World journal of surgery, 1980, Volume: 4, Issue:4 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacterial Infections; Cefamandole; Child; Child, Pre	1980
The role of systemic antibiotics in operations upon the colon. Surgery, gynecology & obstetrics, 1981, Volume: 153, Issue:4 Topics: Anti-Bacterial Agents; Cefamandole; Clindamycin; Colon; Drug Therapy, Combination; Erythromycin; Gen	1981
Perforated appendix and antibiotics. Zeitschrift fur Kinderchirurgie : organ der Deutschen, der Schweizerischen und der Osterreichischen Gesellschaft fur Kinderchirurgie = Surgery in infancy and childhood, 1981, Volume: 32, Issue:4 Topics: Anti-Bacterial Agents; Appendicitis; Child; Clindamycin; Drug Therapy, Combination; Gentamicins; Hum	1981
Prophylactic antibiotics in Caesarean section: effect of a short preoperative course of benzyl penicillin or clindamycin plus gentamicin on postoperative infectious morbidity. Annals of clinical research, 1980, Volume: 12, Issue:2 Topics: Cesarean Section; Clindamycin; Drug Therapy, Combination; Endometritis; Female; Gentamicins; Humans;	1980
Value of oral antibiotic prophylaxis in colorectal surgery. The British journal of surgery, 1995, Volume: 82, Issue:8 Topics: Administration, Oral; Aged; Ciprofloxacin; Colon; Drug Therapy, Combination; Female; Gentamicins; Hu	1995
Primary suture of anorectal abscess. A randomized study comparing treatment with clindamycin vs. clindamycin and Gentacoll. Diseases of the colon and rectum, 1995, Volume: 38, Issue:4 Topics: Abscess; Acute Disease; Adult; Aged; Aged, 80 and over; Anus Diseases; Clindamycin; Collagen; Combin	1995
Optimal timing of wound drain removal following total joint arthroplasty. The Journal of arthroplasty, 1995, Volume: 10, Issue:2 Topics: Aged; Drainage; Female; Floxacillin; Gentamicins; Hematoma; Hip Prosthesis; Humans; Knee Prosthesis;	1995
Comparison of prophylactic ampicillin/sulbactam with gentamicin and metronidazole in elective colorectal surgery: a randomized clinical study. The Journal of hospital infection, 1994, Volume: 27, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Ampicillin; Colon; Colorectal Neoplasms; Colostomy; Drug Therapy, Co	1994
[A randomized prospective study of antibiotic prophylaxis compared to lavage of the surgical wound in nonperforating appendicitis]. Medicina clinica, 1994, Jul-09, Volume: 103, Issue:6 Topics: Acute Disease; Adolescent; Adult; Appendectomy; Appendicitis; Chi-Square Distribution; Child; Female	1994
[Antibiotic prophylaxis in a priori cesarean sections without a high risk of infection. Experiences of a Tunisian maternity department]. Journal de gynecologie, obstetrique et biologie de la reproduction, 1994, Volume: 23, Issue:4 Topics: Adult; Anti-Bacterial Agents; Cephapirin; Cesarean Section; Drug Costs; Escherichia coli Infections;	1994
Antibiotic prophylaxis in cardiac operations. The Annals of thoracic surgery, 1993, Volume: 56, Issue:4 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cardiac Surgical Procedures; Ceftriaxone; Cost-Benefit A	1993
Ceftizoxime versus vancomycin and gentamicin in neurosurgical prophylaxis: a randomized, prospective, blinded clinical study. Neurosurgery, 1993, Volume: 33, Issue:5 Topics: Ceftizoxime; Central Nervous System Diseases; Double-Blind Method; Drug Therapy, Combination; Gentam	1993
Ceftriaxone is more effective than gentamicin/metronidazole prophylaxis in reducing wound and urinary tract infections after bowel operations. Results of a controlled, randomized, blind clinical trial. Diseases of the colon and rectum, 1993, Volume: 36, Issue:9 Topics: Aged; Aged, 80 and over; Bacteria; Ceftriaxone; Drug Therapy, Combination; Female; Gentamicins; Huma	1993
Ceftizoxime versus vancomycin and gentamicin in neurosurgical prophylaxis: a randomized, prospective, blinded clinical study. Neurosurgery, 1993, Volume: 33, Issue:3 Topics: Adolescent; Adult; Aged; Brain Diseases; Ceftizoxime; Craniotomy; Double-Blind Method; Drug Therapy,	1993
Comment; ceftizoxime versus vancomycin and gentamicin in neurosurgical prophylaxis. Neurosurgery, 1993, Volume: 33, Issue:3 Topics: Adult; Brain Diseases; Ceftizoxime; Double-Blind Method; Drug Therapy, Combination; Gentamicins; Hum	1993
Comparative study of a collagen corneal shield and a subconjunctival injection at the end of cataract surgery. Journal of cataract and refractive surgery, 1993, Volume: 19, Issue:1 Topics: Aged; Biological Dressings; Cataract Extraction; Collagen; Conjunctiva; Dexamethasone; Drug Delivery	1993
Piperacillin monotherapy compared with metronidazole and gentamicin combination in penetrating abdominal trauma. The Journal of trauma, 1993, Volume: 34, Issue:2 Topics: Abdominal Injuries; Adolescent; Adult; Aged; Drug Administration Schedule; Drug Therapy, Combination	1993
Subcuticular skin closure as a standard approach to emergency appendectomy in children: prospective clinical trial. World journal of surgery, 1996, Volume: 20, Issue:1 Topics: Adolescent; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antitrichomonal Agents; Appendectomy; Chi	1996
[Prevention of surgical wound infections after appendectomy: intravenous versus rectal metronidazole]. Revista medica de Chile, 1995, Volume: 123, Issue:8 Topics: Administration, Rectal; Adolescent; Adult; Aged; Appendectomy; Female; Gentamicins; Humans; Injectio	1995
Perioperative antimicrobial prophylaxis in neurosurgery: clinical trial of systemic flomoxef administration and saline containing gentamicin for irrigation. Neurologia medico-chirurgica, 1996, Volume: 36, Issue:6 Topics: Adult; Aged; Anti-Bacterial Agents; Brain; Cephalosporins; Dose-Response Relationship, Drug; Drug Th	1996
[Modification of laparotomy wound healing in colon surgery by local antibiotic administration]. Zentralblatt fur Chirurgie, 1996, Volume: 121 Suppl Topics: Antibiotic Prophylaxis; Colonic Diseases; Drug Implants; Drug Therapy, Combination; Gentamicins; Hum	1996
Postoperative contamination after using vancomycin and gentamicin during phacoemulsification. Archives of ophthalmology (Chicago, Ill. : 1960), 1997, Volume: 115, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Anterior Chamber; Anti-Bacterial Agents; Aqueous Humor; Bacteria; Co	1997
Comparison of three prophylactic antibiotic regimens in clean-contaminated head and neck surgery. Head & neck, 1997, Volume: 19, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Antibiot	1997
Prevention of wound infection in elective colorectal surgery by local application of a gentamicin-containing collagen sponge. The European journal of surgery. Supplement. : = Acta chirurgica. Supplement, 1997, Issue:578 Topics: Administration, Oral; Adult; Aged; Analysis of Variance; Anti-Bacterial Agents; Collagen; Colorectal	1997
[Combination use of second generation cephem and isepamicin for the treatment of post-surgical infection of the lower digestive tract]. The Japanese journal of antibiotics, 1997, Volume: 50, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefmetazole; Cefotiam; Cefuroxime; Cephalospo	1997
A double-blind, randomized study of three antimicrobial regimens in the prevention of infections after elective colorectal surgery. Diagnostic microbiology and infectious disease, 1997, Volume: 29, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cefoxitin; Ceftizoxime; Cephalosporins; Cepha	1997
Antibiotic prophylaxis in cardiac surgery. The Journal of cardiovascular surgery, 1997, Volume: 38, Issue:6 Topics: Aged; Amoxicillin; Antibiotic Prophylaxis; Cardiac Surgical Procedures; Cefuroxime; Cephalosporins;	1997
[Results of prophylactic and curative antibiotic therapy in biliary surgery]. Przeglad lekarski, 1997, Volume: 54, Issue:7-8 Topics: Anti-Bacterial Agents; Antibiotic Prophylaxis; Clindamycin; Female; Gallstones; Gentamicins; Humans;	1997
Effectiveness of collagen-gentamicin implant for treatment of "dirty" abdominal wounds. World journal of surgery, 1999, Volume: 23, Issue:2 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Local;	1999
Once daily, high dose versus divided, low dose gentamicin for open fractures. Clinical orthopaedics and related research, 1999, Issue:366 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cefazolin; Cephalosporins; Debridement; Drug Adminis	1999
Collagen tampons as aminoglycoside carriers to reduce postoperative infection rate in prosthetic repair of groin hernias. The European journal of surgery = Acta chirurgica, 2001, Volume: 167, Issue:2 Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Collagen; Drug Carriers; Femal	2001
[Antibiotic prophylaxis in oncologic pharyngolaryngeal surgery: ceftriaxone versus clindamycin and gentamycin]. Acta otorrinolaringologica espanola, 2001, Volume: 52, Issue:2 Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Ceftriaxone; Cephalosporins; Clindamycin; Dru	2001
Improvement of perineal wound healing by local administration of gentamicin-impregnated collagen fleeces after abdominoperineal excision of rectal cancer. American journal of surgery, 2001, Volume: 182, Issue:5 Topics: Absorbable Implants; Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents;	2001
[Indication for and technic of gentamycin-PMMA-spheres insertion in bone and soft tissue defects]. Aktuelle Probleme in Chirurgie und Orthopadie, 1979, Issue:12 Topics: Abscess; Adolescent; Adult; Aged; Chronic Disease; Clinical Trials as Topic; Female; Gentamicins; Hu	1979
[Gentamycin-PMMA-spheres in bone and soft tissue infections - results from the occupational co-operative accident hospital Frankfurt/Main]. Aktuelle Probleme in Chirurgie und Orthopadie, 1979, Issue:12 Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Drug Evaluation; Female; Fracture Fixation, Inter	1979
[Gentamycin-PMMA in joint prosthesis. Indication and technic in the use of Refobacin-Palacos in joint prosthesis]. Aktuelle Probleme in Chirurgie und Orthopadie, 1979, Issue:12 Topics: Ankle Joint; Bone Cements; Clinical Trials as Topic; Evaluation Studies as Topic; Gentamicins; Hip J	1979
[Results of prophylactic use of Refobacin-Palacos in implantation of endoprostheses of the hip joint in Hannover]. Aktuelle Probleme in Chirurgie und Orthopadie, 1979, Issue:12 Topics: Adult; Aged; Bone Cements; Clinical Trials as Topic; Evaluation Studies as Topic; Female; Gentamicin	1979
[Prospective study on the effect of gentamycin-Palacos in 200 total hip prostheses]. Aktuelle Probleme in Chirurgie und Orthopadie, 1979, Issue:12 Topics: Bone Cements; Clinical Trials as Topic; Follow-Up Studies; Gentamicins; Germany, West; Hip Joint; Hu	1979
Prophylactic systemic antibiotics in colorectal surgery. Lancet (London, England), 1977, Jul-02, Volume: 2, Issue:8027 Topics: Abscess; Adult; Aged; Bacteroides fragilis; Clinical Trials as Topic; Colitis; Colon; Colonic Neopla	1977
Septic complications in colo-rectal surgery after 24 hours versus 60 hours of preoperative antibiotic bowel preparation. I. Prospective, randomized, double-blind clinical study. Acta chirurgica Scandinavica, 1978, Volume: 144, Issue:7-8 Topics: Adult; Aged; Anti-Bacterial Agents; Clinical Trials as Topic; Colectomy; Colon; Colostomy; Double-Bl	1978
Septic complications in colo-rectal surgery after 24 hours versus 60 hours of preoperative antibiotic bowel preparation. II. Significance of bacterial concentrations in the bowel for contamination of the operation field and subsequent wound infection. Acta chirurgica Scandinavica, 1978, Volume: 144, Issue:7-8 Topics: Adult; Aged; Anti-Bacterial Agents; Ascitic Fluid; Bacteria; Clinical Trials as Topic; Colectomy; Co	1978
Sisomicin in surgical infections. Laboratory and clinical studies. Arzneimittel-Forschung, 1979, Volume: 29, Issue:1 Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Female; Gentamicins; Humans; Kinetics; Male; Midd	1979
Parenteral antibiotics in elective colon surgery? A prospective, controlled clinical study. Surgery, 1979, Volume: 86, Issue:1 Topics: Aged; Anti-Bacterial Agents; Clindamycin; Clinical Trials as Topic; Colectomy; Double-Blind Method;	1979
Bacteriologic effects of prophylactic antibiotics in cesarean section. American journal of obstetrics and gynecology, 1976, Sep-15, Volume: 126, Issue:2 Topics: Ampicillin; Bacteria; Cesarean Section; Clindamycin; Clinical Trials as Topic; Drug Therapy, Combina	1976
Antibiotics in biliary disease: the relative importance of antibiotic concentrations in the bile and serum. Gut, 1976, Volume: 17, Issue:7 Topics: Anti-Bacterial Agents; Bile; Biliary Tract Diseases; Clinical Trials as Topic; Gentamicins; Humans;	1976
A controlled trial of parenteral prophylactic gentamicin therapy in biliary surgery. The British journal of surgery, 1975, Volume: 62, Issue:4 Topics: Aged; Bile; Biliary Tract Surgical Procedures; Cholelithiasis; Drainage; Female; Gentamicins; Humans	1975
Intraocular gentamicin as intraoperative prophylaxis in South India eye camps. The British journal of ophthalmology, 1977, Volume: 61, Issue:4 Topics: Bacterial Infections; Cataract Extraction; Chloramphenicol; Eye Diseases; Gentamicins; Humans; India	1977
Prophylactic use of gentamicin in colonic and rectal surgery. The Medical journal of Australia, 1975, Oct-11, Volume: 2, Issue:15 Topics: Abscess; Clinical Trials as Topic; Colon; Feces; Female; Gentamicins; Humans; Intestinal Fistula; Ma	1975
Antibiotic treatment of biliary sepsis. The Surgical clinics of North America, 1975, Volume: 55, Issue:6 Topics: Ampicillin; Anti-Bacterial Agents; Bile; Biliary Tract Diseases; Cholangitis; Cholecystectomy; Clini	1975
Treatment of surgical infections with tobramcin. The American surgeon, 1975, Volume: 41, Issue:5 Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteria; Burns; Child; Child, Preschool; Drug Evalu	1975
Antibiotic prophylaxis in acute non-perforated appendicitis in children: single dose of metronidazole and gentamicin. Journal of the Royal College of Surgeons of Edinburgh, 1992, Volume: 37, Issue:2 Topics: Acute Disease; Adolescent; Appendicitis; Child; Child, Preschool; Female; Gentamicins; Humans; Male;	1992
[Treatment of pilonidal sinus with excision and primary suture using a local, resorbable antibiotic carrier. Results of a prospective randomized study]. Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen, 1992, Volume: 63, Issue:9 Topics: Abscess; Administration, Topical; Combined Modality Therapy; Follow-Up Studies; Gentamicins; Humans;	1992
[Prevention of post-operative infection by using antibiotics of 217 cases of cesarean section]. Zhonghua fu chan ke za zhi, 1992, Volume: 27, Issue:2 Topics: Ampicillin; Cesarean Section; Female; Gentamicins; Humans; Penicillins; Pregnancy; Premedication; Pr	1992
Risk factors in postoperative neurosurgical infection. A prospective study. Acta neurochirurgica, 1992, Volume: 119, Issue:1-4 Topics: Administration, Oral; Bacterial Infections; Cefotaxime; Central Nervous System Diseases; Cephalexin;	1992
Comparative study of single dose and five days dose of gentamicin as prophylaxis in appendicectomy. JPMA. The Journal of the Pakistan Medical Association, 1992, Volume: 42, Issue:6 Topics: Adult; Appendectomy; Child; Drug Administration Schedule; Female; Gentamicins; Humans; Male; Middle	1992
Role of prophylactic antibiotics in surgery for advanced head and neck cancer. The Journal of laryngology and otology, 1992, Volume: 106, Issue:7 Topics: Adult; Aged; Ampicillin; Anti-Bacterial Agents; Cephalexin; Combined Modality Therapy; Drug Therapy,	1992
Amoxicillin-clavulanate prophylaxis against wound infections after clean-contaminated surgery. A controlled, randomized, prospective study. The European journal of surgery = Acta chirurgica, 1991, Volume: 157, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Clavulan	1991
[Bacteriocidal effect of preoperative use of gentamicin in comparison with PVP-iodine solution]. Fortschritte der Ophthalmologie : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft, 1991, Volume: 88, Issue:6 Topics: Cataract Extraction; Conjunctiva; Endophthalmitis; Gentamicins; Humans; Ophthalmic Solutions; Povido	1991
A randomized clinical trial of ampicillin, gentamicin and clindamycin versus cefotaxime and clindamycin in children with ruptured appendicitis. Surgery, gynecology & obstetrics, 1991, Volume: 172, Issue:5 Topics: Adolescent; Ampicillin; Appendicitis; Cefotaxime; Child; Child, Preschool; Clindamycin; Combined Mod	1991
Local gentamicin application for perineal wound healing following abdominoperineal rectum excision. American journal of surgery, 1991, Volume: 162, Issue:5 Topics: Administration, Rectal; Adult; Aged; Aged, 80 and over; Anus Neoplasms; Colorectal Surgery; Female;	1991
Multicenter study of aztreonam in the prophylaxis of colorectal, gynecologic and urologic surgery. Chemotherapy, 1989, Volume: 35 Suppl 1 Topics: Abdomen; Adult; Aged; Aged, 80 and over; Aztreonam; Cefotaxime; Colorectal Surgery; Female; Gentamic	1989
[Effectiveness of perioperative preventive use of antibiotics with ampicillin/gentamycin or cefotiam in abdominal cesarean section]. Zentralblatt fur Gynakologie, 1989, Volume: 111, Issue:10 Topics: Ampicillin; Cefotiam; Cesarean Section; Clinical Trials as Topic; Drug Therapy, Combination; Female;	1989
Presumptive antibiotics for penetrating abdominal wounds. Surgery, gynecology & obstetrics, 1989, Volume: 169, Issue:2 Topics: Abdominal Injuries; Adult; Anti-Bacterial Agents; Clindamycin; Clinical Trials as Topic; Drug Admini	1989
Comparative multicenter study on efficacy and safety of aztreonam and gentamicin in prophylaxis of high-risk colorectal surgery. Journal of chemotherapy (Florence, Italy), 1989, Volume: 1 Suppl 2 Topics: Adult; Aged; Aged, 80 and over; Aztreonam; Colon; Female; Gentamicins; Gram-Negative Bacteria; Gram-	1989
A randomized trial to compare amoxycillin/clavulanate with metronidazole plus gentamicin in prophylaxis in elective colorectal surgery. The Journal of antimicrobial chemotherapy, 1989, Volume: 24 Suppl B Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; Amoxicillin-Potassium Clavulanate Combinati	1989
A comparative study of cefotaxime sodium versus a combination of cefapirin and gentamicin in the prophylactic treatment of patients undergoing cholecystectomy. Methods and findings in experimental and clinical pharmacology, 1989, Volume: 11, Issue:11 Topics: Adult; Aged; Cefotaxime; Cephalosporins; Cephapirin; Cholecystectomy; Creatinine; Drug Therapy, Comb	1989
Clinical trials are usually beneficial to patients and hospitals. The New Zealand medical journal, 1989, Sep-13, Volume: 102, Issue:875 Topics: Anti-Bacterial Agents; Cefoxitin; Ceftriaxone; Clinical Trials as Topic; Gentamicins; Hospitalizatio	1989
A single prophylactic antibiotic for emergency appendicectomy? Chemotherapy, 1989, Volume: 35, Issue:5 Topics: Adolescent; Adult; Ampicillin; Appendectomy; Bacteria, Aerobic; Ceftriaxone; Drug Therapy, Combinati	1989
Cefotetan compared with gentamicin and tinidazole in acute abdominal surgery. The Journal of hospital infection, 1986, Volume: 7, Issue:1 Topics: Abdomen, Acute; Bacteria, Aerobic; Bacteria, Anaerobic; Bacteriuria; Cefotetan; Cephamycins; Enteroc	1986
Randomized clinical trial of intra-operative antimicrobial prophylaxis of infection after neurosurgical procedures. The Journal of hospital infection, 1986, Volume: 8, Issue:3 Topics: Anti-Bacterial Agents; Bacterial Infections; Cerebrospinal Fluid Shunts; Clinical Trials as Topic; D	1986
Failure of topically applied antibiotics, added to systemic prophylaxis, to reduce perineal wound infection in abdominoperineal excision of the rectum. Acta chirurgica Scandinavica, 1988, Volume: 154, Issue:10 Topics: Administration, Rectal; Adult; Aged; Clinical Trials as Topic; Female; Gentamicins; Humans; Immunity	1988
Comparison of short-term antibiotic cover with a third-generation cephalosporin against conventional five-day therapy using metronidazole with an aminoglycoside in emergency and complicated colorectal surgery. Diseases of the colon and rectum, 1988, Volume: 31, Issue:1 Topics: Cefotetan; Cephamycins; Colonic Diseases; Drug Administration Schedule; Drug Therapy, Combination; E	1988
Prophylactic antibiotics in elective colorectal surgery. The British journal of surgery, 1988, Volume: 75, Issue:8 Topics: Administration, Oral; Anti-Bacterial Agents; Colon; Colonic Neoplasms; Erythromycin; Female; Gentami	1988
One-stage versus two-stage amputation for wet gangrene of the lower extremity: a randomized study. Journal of vascular surgery, 1988, Volume: 8, Issue:4 Topics: Aged; Amputation, Surgical; Clindamycin; Foot Diseases; Gangrene; Gentamicins; Humans; Middle Aged;	1988
A comparison of mezlocillin versus clindamycin/gentamicin for the treatment of postcesarean endomyometritis. American journal of obstetrics and gynecology, 1988, Volume: 158, Issue:2 Topics: Cesarean Section; Clindamycin; Clinical Trials as Topic; Drug Therapy, Combination; Endometritis; Fe	1988
[Preventive preoperative antibiotic therapy in elective colon surgery. A controlled prospective randomized study]. Schweizerische medizinische Wochenschrift, 1987, Apr-11, Volume: 117, Issue:15 Topics: Aged; Anti-Bacterial Agents; Cefoxitin; Clindamycin; Clinical Trials as Topic; Colectomy; Colonic Di	1987
Comparison of cefotetan and gentamicin/ampicillin in high-risk biliary tract surgery. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl Topics: Ampicillin; Biliary Tract Diseases; Cefotetan; Clinical Trials as Topic; Drug Therapy, Combination;	1987
Wound sepsis after colorectal surgery: the effect of cefotetan lavage. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl Topics: Bacteria, Aerobic; Bacteria, Anaerobic; Cefotetan; Clinical Trials as Topic; Colonic Diseases; Drug	1987
Perioperative infection prophylaxis in colon surgery. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy, 1987, Volume: 6, Issue:2 Suppl Topics: Cefotiam; Ceftriaxone; Clinical Trials as Topic; Colonic Diseases; Drug Therapy, Combination; Female	1987
Antibiotic prophylaxis in aortic and peripheral arterial surgery in the presence of infected extremity lesions. Results of a prospective evaluation. Drugs, 1988, Volume: 35 Suppl 2 Topics: Adult; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Cefotaxime; Cloxacillin; Drug Therapy,	1988
Cefoxitin versus clindamycin and gentamicin in the treatment of postcesarean section infections. Obstetrics and gynecology, 1986, Volume: 67, Issue:3 Topics: Adult; Bacterial Infections; Cefoxitin; Cesarean Section; Clindamycin; Clinical Trials as Topic; Dru	1986
A prospective comparison of gentamicin and metronidazole and moxalactam in the prevention of septic complications associated with elective operations of the colon and rectum. Surgery, gynecology & obstetrics, 1986, Volume: 162, Issue:6 Topics: Adult; Aged; Clinical Trials as Topic; Colon; Double-Blind Method; Drug Therapy, Combination; Female	1986
Perioperative antibiotic prophylaxis for prevention of postoperative neurosurgical infections. A randomized clinical trial. Journal of neurosurgery, 1987, Volume: 66, Issue:5 Topics: Adult; Anti-Bacterial Agents; Cefazolin; Clinical Trials as Topic; Female; Gentamicins; Humans; Intr	1987
Efficacy of cefazolin, cefamandole, and gentamicin as prophylactic agents in cardiac surgery. Results of a prospective, randomized, double-blind trial in 1030 patients. Annals of surgery, 1987, Volume: 206, Issue:6 Topics: Cardiac Surgical Procedures; Cefamandole; Cefazolin; Costs and Cost Analysis; Double-Blind Method; D	1987
Single dose prophylaxis in elective cholecystectomy. A prospective, double-blind randomized study. American journal of surgery, 1986, Volume: 152, Issue:5 Topics: Adult; Aged; Cholecystectomy; Double-Blind Method; Female; Gentamicins; Humans; Male; Middle Aged; P	1986
Combined topical povidone-iodine and systemic antibiotics in postappendicectomy wound sepsis. The British journal of surgery, 1986, Volume: 73, Issue:12 Topics: Administration, Topical; Adolescent; Adult; Aged; Anti-Bacterial Agents; Appendectomy; Drug Therapy,	1986
An assessment of the need for gram-negative bacterial coverage in antibiotic prophylaxis for oncological head and neck surgery. The Journal of infectious diseases, 1987, Volume: 155, Issue:2 Topics: Clindamycin; Double-Blind Method; Drug Therapy, Combination; Gentamicins; Gram-Negative Bacteria; He	1987
[Prospective randomized study: cefuroxime and netilmicin versus ceftriaxone as prophylaxis in vascular surgery]. Wiener medizinische Wochenschrift. Supplement, 1985, Volume: 87 Topics: Aged; Cefotaxime; Ceftriaxone; Cefuroxime; Cephalosporins; Clinical Trials as Topic; Female; Gentami	1985
Ampicillin vs. ampicillin-gentamicin prophylaxis in high-risk primary cesarean section. The Journal of reproductive medicine, 1986, Volume: 31, Issue:1 Topics: Ampicillin; Cesarean Section; Drug Therapy, Combination; Female; Gentamicins; Humans; Obstetric Labo	1986
Letter: Antibiotic-bone-cement mixtures in prevention of infection following total joint replacement. Lancet (London, England), 1974, Oct-12, Volume: 2, Issue:7885 Topics: Bone Cements; Clinical Trials as Topic; Fusidic Acid; Gentamicins; Hip; Humans; Joint Prosthesis; Po	1974
Short term routine antibiotic prophylaxis in surgery. The British journal of surgery, 1974, Volume: 61, Issue:9 Topics: Aminoglycosides; Anti-Bacterial Agents; Bacteroides; Clinical Trials as Topic; Creatinine; Drug Ther	1974
Letter: Cephaloridine and gentamicin in prophylaxis of surgical wound infection. British medical journal, 1974, Jun-08, Volume: 2, Issue:5918 Topics: Cephaloridine; Gentamicins; Humans; Surgical Wound Infection	1974
Antibiotic prophylaxis in cataract surgery. American journal of ophthalmology, 1972, Volume: 74, Issue:4 Topics: Bacterial Infections; Bacteriological Techniques; Cataract Extraction; Chloramphenicol; Clinical Tri	1972
[Clinical evaluation of antibacterial chemotherapy in surgery]. Casopis lekaru ceskych, 1972, Nov-03, Volume: 111, Issue:45 Topics: Anti-Bacterial Agents; Clinical Trials as Topic; Gentamicins; Humans; Postoperative Complications; S	1972
Combined carbenicillin and gentamicin for prophylaxis of post-operative infection following major abdominal surgery. Postgraduate medical journal, 1969, Volume: 45, Issue:530 Topics: Abdomen; Adult; Aged; Drug Synergism; Gentamicins; Humans; Infection Control; Middle Aged; Penicilli	1969

gentamicin and Infection, Postoperative Wound