Page last updated: 2024-10-27

gentamicin and Infant, Small for Gestational Age

gentamicin has been researched along with Infant, Small for Gestational Age in 7 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Infant, Small for Gestational Age: An infant having a birth weight lower than expected for its gestational age.

Research Excerpts

ExcerptRelevanceReference
"This retrospective cohort study conducted at 330 neonatal intensive care units (2002-2014) included inborn infants exposed to gentamicin with available hearing screen results, and excluded infants with incomplete dosing data and major congenital anomalies."1.48Evaluation of Gentamicin Exposure in the Neonatal Intensive Care Unit and Hearing Function at Discharge. ( Benjamin, DK; Bretzius, OM; Brown, N; Clark, RH; Fitz-Henley, JA; Gonzalez, D; Gray, KD; Hornik, CP; Puia-Dumitrescu, M; Smith, PB; Ssengonzi, R; Wechsler, CS, 2018)
" Steady state peak and trough serum gentamicin concentrations were used to calculate clearance (Cl), elimination constant (Kel), volume of distribution (Vd), and half-life (t1/2 ) in infants (n = 236) who received ≥48 hours therapy."1.40Impact of small-for-gestational age (SGA) status on gentamicin pharmacokinetics in neonates. ( Edwards, D; Lulic-Botica, M; Natarajan, G; Sheer, T; Thomas, RL, 2014)
" The predictive value of a designed dose regimen was evaluated at steady-state, after dosage adjustment using two plasma concentration values: the minimum plasma concentration was below 2 mg/L in 93% of the patients; the plasma concentration observed within 1 h after completion of the infusion was (mean +/- SD) 5."1.27Gentamicin monitoring in neonates. ( Badoual, J; d'Athis, P; de Lauture, D; Olive, G; Pons, G; Rey, E; Richard, MO, 1988)
"In a retrospective study of 72 neonates during treatment with gentamicin, poor correlation was found between dosage based on body weight and gentamicin serum concentrations."1.27A simplified model for adjustment of gentamicin dosage in newborn infants. ( Broberger, U; Herngren, L; Wretlind, B, 1986)
" Dosage was 2-2."1.26Gentamicin dosage in preterm and term neonates. ( Assael, BM; Gianni, V; Marini, A; Peneff, P; Sereni, F, 1977)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Puia-Dumitrescu, M1
Bretzius, OM1
Brown, N1
Fitz-Henley, JA1
Ssengonzi, R1
Wechsler, CS1
Gray, KD1
Benjamin, DK1
Smith, PB1
Clark, RH1
Gonzalez, D1
Hornik, CP1
Aly, H1
Ez El Din, Z1
Soliman, RM1
Bhattacharjee, I1
Abdellatif, MAK1
Kamel, A1
Salah, H1
Lulic-Botica, M1
Sheer, T1
Edwards, D1
Thomas, RL1
Natarajan, G1
Assael, BM1
Gianni, V1
Marini, A1
Peneff, P1
Sereni, F1
Borderon, E1
Thieffry, JC1
Jamet, O1
Poisson, D1
Boisseau, C1
Farid, IA1
Pons, G1
d'Athis, P1
Rey, E1
de Lauture, D1
Richard, MO1
Badoual, J1
Olive, G1
Herngren, L1
Broberger, U1
Wretlind, B1

Other Studies

7 other studies available for gentamicin and Infant, Small for Gestational Age

ArticleYear
Evaluation of Gentamicin Exposure in the Neonatal Intensive Care Unit and Hearing Function at Discharge.
    The Journal of pediatrics, 2018, Volume: 203

    Topics: Anti-Bacterial Agents; Cohort Studies; Dose-Response Relationship, Drug; Female; Gentamicins; Gestat

2018
Renal function in small for gestational age preterm infants.
    Journal of perinatology : official journal of the California Perinatal Association, 2019, Volume: 39, Issue:9

    Topics: Acetylglucosaminidase; Anti-Bacterial Agents; Biomarkers; Creatinine; Female; Gentamicins; Humans; I

2019
Impact of small-for-gestational age (SGA) status on gentamicin pharmacokinetics in neonates.
    Journal of clinical pharmacology, 2014, Volume: 54, Issue:1

    Topics: Anti-Bacterial Agents; Birth Weight; Creatinine; Female; Gentamicins; Gestational Age; Half-Life; Hu

2014
Gentamicin dosage in preterm and term neonates.
    Archives of disease in childhood, 1977, Volume: 52, Issue:11

    Topics: Body Weight; Child, Preschool; Gentamicins; Gestational Age; Humans; Infant; Infant, Newborn; Infant

1977
Observations on the intestinal colonization by Pseudomonas aeruginosa in newborn infants.
    Biology of the neonate, 1990, Volume: 57, Issue:2

    Topics: Cefotaxime; Colistin; Drug Therapy, Combination; Escherichia coli; Feces; Female; Gentamicins; Human

1990
Gentamicin monitoring in neonates.
    Therapeutic drug monitoring, 1988, Volume: 10, Issue:4

    Topics: Age Factors; Gentamicins; Half-Life; Humans; Infant, Newborn; Infant, Premature; Infant, Small for G

1988
A simplified model for adjustment of gentamicin dosage in newborn infants.
    Acta paediatrica Scandinavica, 1986, Volume: 75, Issue:2

    Topics: Bacterial Infections; Gentamicins; Humans; Infant; Infant, Newborn; Infant, Premature, Diseases; Inf

1986