gentamicin has been researched along with Hypoxia in 25 studies
Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We utilized a newborn rat model of hypoxia/reoxygenation (H/R) that resembles human necrotizing enterocolitis (NEC) to investigate the effects of omeprazole and/or gentamicin on the formation of free oxygen radicals (FOR) and bowel histopathology." | 7.73 | Effects of omeprazole and gentamicin on the biochemical and histopathological alterations of the hypoxia/ reoxygenation induced intestinal injury in newborn rats. ( Aritürk, E; Aydin, BK; Aydin, O; Bernay, F; Biçakçi, U; Eren, Z; Rizalar, R; Tander, B, 2005) |
| " We used our well-established global hypoxia-asphyxia newborn pig model to evaluate the effect of mild hypothermia after hypoxia-ischemia on gentamicin pharmacokinetics." | 7.70 | Influence of mild hypothermia after hypoxia-ischemia on the pharmacokinetics of gentamicin in newborn pigs. ( Hoem, NO; Lindgren, CG; Melby, K; Porter, H; Satas, S; Thoresen, M; Whitelaw, A, 2000) |
| "In an attempt to assess the erythropoietin (Epo) production site(s) in rat kidney, Epo response to hypoxia and renal histopathological changes were studied in rats administered with graded doses of gentamicin." | 7.69 | Erythropoietin response to acute hypobaric or anaemic hypoxia in gentamicin-administered rats. ( Enoki, Y; Kohzuki, H; Matsumura, K; Ohga, Y; Sakata, S; Shimizu, S, 1994) |
| "The activity of gentamicin is known to be decreased in acidic environments, and both the peritoneum during peritonitis and the interior of abscesses have been shown to be acidic and hypoxic." | 7.69 | Aztreonam vs. gentamicin in experimental peritonitis and intra-abdominal abscess formation. ( Adams, RB; Pruett, TL; Sawyer, RG, 1994) |
| " Toxicity is dose related, but some patients may still develop hearing loss even under safe dosage." | 5.37 | Transient ischemia/hypoxia enhances gentamicin ototoxicity via caspase-dependent cell death pathway. ( Hsu, CJ; Kao, MC; Lai, CH; Lin, CD; Lin, CW; Lin, CY; Tang, CH; Tsai, MH; Wei, IH, 2011) |
| "Toxic renal failure induced by gentamicin, glycerol, or cisplatin, as well as ischemic renal failure in vivo and hypoxia/reoxygenation of tubular epithelial cells in vitro, induces the production of reactive oxygen metabolites (ROM)." | 4.81 | Apoptotic pathways of oxidative damage to renal tubular epithelial cells. ( Basnakian, AG; Kaushal, GP; Shah, SV, 2002) |
| "We utilized a newborn rat model of hypoxia/reoxygenation (H/R) that resembles human necrotizing enterocolitis (NEC) to investigate the effects of omeprazole and/or gentamicin on the formation of free oxygen radicals (FOR) and bowel histopathology." | 3.73 | Effects of omeprazole and gentamicin on the biochemical and histopathological alterations of the hypoxia/ reoxygenation induced intestinal injury in newborn rats. ( Aritürk, E; Aydin, BK; Aydin, O; Bernay, F; Biçakçi, U; Eren, Z; Rizalar, R; Tander, B, 2005) |
| " We used our well-established global hypoxia-asphyxia newborn pig model to evaluate the effect of mild hypothermia after hypoxia-ischemia on gentamicin pharmacokinetics." | 3.70 | Influence of mild hypothermia after hypoxia-ischemia on the pharmacokinetics of gentamicin in newborn pigs. ( Hoem, NO; Lindgren, CG; Melby, K; Porter, H; Satas, S; Thoresen, M; Whitelaw, A, 2000) |
| "In an attempt to assess the erythropoietin (Epo) production site(s) in rat kidney, Epo response to hypoxia and renal histopathological changes were studied in rats administered with graded doses of gentamicin." | 3.69 | Erythropoietin response to acute hypobaric or anaemic hypoxia in gentamicin-administered rats. ( Enoki, Y; Kohzuki, H; Matsumura, K; Ohga, Y; Sakata, S; Shimizu, S, 1994) |
| "The activity of gentamicin is known to be decreased in acidic environments, and both the peritoneum during peritonitis and the interior of abscesses have been shown to be acidic and hypoxic." | 3.69 | Aztreonam vs. gentamicin in experimental peritonitis and intra-abdominal abscess formation. ( Adams, RB; Pruett, TL; Sawyer, RG, 1994) |
| "5 mM), gentamicin (4 mM), and hypoxia; altered inotropic reactivity to these interventions followed similar temporal development as the postendotoxin changes in basal contractile parameters." | 3.67 | Development of myocardial dysfunction in endotoxin shock. ( Adams, HR; Parker, JL, 1985) |
| "Infants that succumb to Sudden Infant Death Syndrome (SIDS) have been identified with inner ear dysfunction (IED) at birth and on autopsy." | 1.43 | Inner ear lesion and the differential roles of hypoxia and hypercarbia in triggering active movements: Potential implication for the Sudden Infant Death Syndrome. ( Allen, T; Chae, Y; Ramirez, JM; Ramirez, S; Rubens, DD; Villagracia, L, 2016) |
| " Toxicity is dose related, but some patients may still develop hearing loss even under safe dosage." | 1.37 | Transient ischemia/hypoxia enhances gentamicin ototoxicity via caspase-dependent cell death pathway. ( Hsu, CJ; Kao, MC; Lai, CH; Lin, CD; Lin, CW; Lin, CY; Tang, CH; Tsai, MH; Wei, IH, 2011) |
| "The effect of anoxia persisted, although less remarkable (P=0." | 1.31 | Netilmicin effect on urinary retinol binding protein (RBP) and N-acetyl-beta-D-glucosaminidase (NAG) in preterm newborns with and without anoxia. ( Cataldi, L; Fanos, V; Mussap, M; Plebani, M; Verlato, G, 2002) |
| "Cardiac effects of endotoxin shock were compared in left atrial preparations isolated from guinea pigs and rats injected with 4 or 8 mg/kg E coli endotoxin." | 1.27 | Contractile function of heart muscle isolated from endotoxin-shocked guinea pigs and rats. ( Parker, JL, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (36.00) | 18.7374 |
| 1990's | 6 (24.00) | 18.2507 |
| 2000's | 7 (28.00) | 29.6817 |
| 2010's | 3 (12.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Allen, T | 2 |
| Garcia Iii, AJ | 1 |
| Tang, J | 1 |
| Ramirez, JM | 2 |
| Rubens, DD | 2 |
| Ramirez, S | 1 |
| Villagracia, L | 1 |
| Chae, Y | 1 |
| Lin, CD | 1 |
| Kao, MC | 1 |
| Tsai, MH | 2 |
| Lai, CH | 1 |
| Wei, IH | 1 |
| Tang, CH | 1 |
| Lin, CW | 1 |
| Hsu, CJ | 1 |
| Lin, CY | 1 |
| Basnakian, AG | 1 |
| Kaushal, GP | 1 |
| Shah, SV | 1 |
| Healy, CM | 1 |
| Palazzi, DL | 1 |
| Edwards, MS | 1 |
| Campbell, JR | 1 |
| Baker, CJ | 1 |
| Yarin, YM | 1 |
| Amarjargal, N | 1 |
| Fuchs, J | 1 |
| Haupt, H | 1 |
| Mazurek, B | 1 |
| Morozova, SV | 1 |
| Gross, J | 1 |
| Biçakçi, U | 1 |
| Tander, B | 1 |
| Aritürk, E | 1 |
| Aydin, BK | 1 |
| Aydin, O | 1 |
| Rizalar, R | 1 |
| Eren, Z | 1 |
| Bernay, F | 1 |
| Guignard, JP | 1 |
| Parker, JL | 2 |
| Weismann, D | 1 |
| Herrig, J | 1 |
| McWeeny, O | 1 |
| Shimizu, S | 1 |
| Enoki, Y | 1 |
| Sakata, S | 1 |
| Kohzuki, H | 1 |
| Ohga, Y | 1 |
| Matsumura, K | 1 |
| Sawyer, RG | 1 |
| Adams, RB | 1 |
| Pruett, TL | 1 |
| Kawashiro, N | 1 |
| Tsuchihashi, N | 1 |
| Koga, K | 1 |
| Ito, Y | 1 |
| Kawano, H | 1 |
| Kalaidjieva, V | 1 |
| Satas, S | 1 |
| Hoem, NO | 1 |
| Melby, K | 1 |
| Porter, H | 1 |
| Lindgren, CG | 1 |
| Whitelaw, A | 1 |
| Thoresen, M | 1 |
| Kalaidjieva, VC | 1 |
| Iliev, ZK | 1 |
| Chen, B | 1 |
| Jia, C | 1 |
| Su, Y | 1 |
| Cataldi, L | 1 |
| Mussap, M | 1 |
| Verlato, G | 1 |
| Plebani, M | 1 |
| Fanos, V | 1 |
| Mirhij, NJ | 1 |
| Roberts, RJ | 1 |
| Myers, MG | 1 |
| Ledingham, IM | 1 |
| Whitehead, ML | 1 |
| Lonsbury-Martin, BL | 1 |
| Martin, GK | 1 |
| Jelkmann, W | 1 |
| Marienhoff, N | 1 |
| Giesselmann, S | 1 |
| Busch, L | 1 |
| Adams, HR | 1 |
| Takada, A | 1 |
| Bledsoe, S | 1 |
| Schacht, J | 1 |
| Abbate, EH | 1 |
| Roncoroni, AJ | 1 |
1 review available for gentamicin and Hypoxia
| Article | Year |
|---|---|
Apoptotic pathways of oxidative damage to renal tubular epithelial cells.
Topics: Animals; Apoptosis; Caspase Inhibitors; Caspases; Cisplatin; Endonucleases; Enzyme Activation; Enzym | 2002 |
24 other studies available for gentamicin and Hypoxia
| Article | Year |
|---|---|
Inner ear insult ablates the arousal response to hypoxia and hypercarbia.
Topics: Analysis of Variance; Animals; Animals, Newborn; Anti-Bacterial Agents; Arousal; Disease Models, Ani | 2013 |
Inner ear lesion and the differential roles of hypoxia and hypercarbia in triggering active movements: Potential implication for the Sudden Infant Death Syndrome.
Topics: Animals; Arousal; Ear, Inner; Female; Gentamicins; Humans; Hypercapnia; Hypoxia; Infant; Male; Mice; | 2016 |
Transient ischemia/hypoxia enhances gentamicin ototoxicity via caspase-dependent cell death pathway.
Topics: Animals; Anti-Bacterial Agents; Apoptosis; Blotting, Western; Caspases; Cell Line; Cochlea; Disease | 2011 |
Features of invasive staphylococcal disease in neonates.
Topics: Age of Onset; Anti-Bacterial Agents; Catheters, Indwelling; Coagulase; Cohort Studies; Drug Resistan | 2004 |
Argon protects hypoxia-, cisplatin- and gentamycin-exposed hair cells in the newborn rat's organ of Corti.
Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Antineoplastic Agents; Argon; Case-Control Studies | 2005 |
Effects of omeprazole and gentamicin on the biochemical and histopathological alterations of the hypoxia/ reoxygenation induced intestinal injury in newborn rats.
Topics: Animals; Animals, Newborn; Anti-Bacterial Agents; Anti-Ulcer Agents; Disease Models, Animal; Enteroc | 2005 |
Drugs and the neonatal kidney.
Topics: Asphyxia Neonatorum; Captopril; Gentamicins; Humans; Hypoxia; Indomethacin; Infant, Newborn; Infant, | 1982 |
Contractile function of heart muscle isolated from endotoxin-shocked guinea pigs and rats.
Topics: Animals; Calcium; Gentamicins; Guinea Pigs; Heart Atria; Hypoxia; Male; Myocardial Contraction; Rats | 1983 |
Tissue distribution of gentamicin in lambs: effect of postnatal age and acute hypoxemia.
Topics: Aging; Animals; Blood Gas Analysis; Gentamicins; Hematocrit; Hypoxia; Regional Blood Flow; Sheep; Ti | 1982 |
Erythropoietin response to acute hypobaric or anaemic hypoxia in gentamicin-administered rats.
Topics: Anemia; Animals; Atmospheric Pressure; Blood Volume; Erythropoietin; Gentamicins; Hypoxia; Kidney Tu | 1994 |
Aztreonam vs. gentamicin in experimental peritonitis and intra-abdominal abscess formation.
Topics: Abdominal Abscess; Animals; Aztreonam; Bacteroides fragilis; Bacteroides Infections; beta-Lactam Res | 1994 |
Idiopathic deafness or hearing loss of unknown etiology following discharge from the NICU.
Topics: Child, Preschool; Deafness; Dyspnea; Evoked Potentials, Auditory, Brain Stem; Extracorporeal Membran | 1994 |
Development of bone marrow erythroblastic islands in hypoxic rats with intact or damaged kidney tubules.
Topics: Animals; Bone Marrow; Creatinine; Erythroblasts; Erythropoietin; Gentamicins; Hypoxia; Kidney Diseas | 1998 |
Influence of mild hypothermia after hypoxia-ischemia on the pharmacokinetics of gentamicin in newborn pigs.
Topics: Animals; Animals, Newborn; Blood Glucose; Creatinine; Female; Fluorescence Polarization Immunoassay; | 2000 |
Plasma erythropoietin level in rats after kidney proximal tubular impairment.
Topics: Anemia; Animals; Disease Models, Animal; Erythropoiesis; Erythropoietin; Gentamicins; Hematologic Te | 2000 |
[Experience in the management of severe inhalation injury].
Topics: Adolescent; Adult; Bronchoalveolar Lavage; Burns, Inhalation; Child; Child, Preschool; Dexamethasone | 1999 |
Netilmicin effect on urinary retinol binding protein (RBP) and N-acetyl-beta-D-glucosaminidase (NAG) in preterm newborns with and without anoxia.
Topics: Acetylglucosaminidase; Female; Gentamicins; Humans; Hypoxia; Infant, Newborn; Infant, Premature; Mal | 2002 |
Effects of hypoxemia upon aminoglycoside serum pharmacokinetics in animals.
Topics: Amikacin; Animals; Animals, Newborn; Gentamicins; Half-Life; Hypoxia; Kanamycin; Male; Rabbits; Rats | 1978 |
Septic shock.
Topics: Acid-Base Equilibrium; Adult; Bacteroides; Blood Coagulation Tests; Digitalis Glycosides; Disseminat | 1975 |
Evidence for two discrete sources of 2f1-f2 distortion-product otoacoustic emission in rabbit. II: Differential physiological vulnerability.
Topics: Acoustic Stimulation; Acoustics; Animals; Audiometry; Auditory Fatigue; Cadaver; Ethacrynic Acid; Ge | 1992 |
Lowered plasma erythropoietin in hypoxic rats with kidney tubule lesions.
Topics: Altitude; Animals; Cell Line; Erythropoietin; Gentamicins; Hydronephrosis; Hypoxia; Kidney Tubular N | 1988 |
Development of myocardial dysfunction in endotoxin shock.
Topics: Animals; Calcium; Gentamicins; Guinea Pigs; Heart; Hypoxia; Male; Muscle Contraction; Myocardial Con | 1985 |
An energy-dependent step in aminoglycoside ototoxicity: prevention of gentamicin ototoxicity during reduced endolymphatic potential.
Topics: Aminoglycosides; Aminooxyacetic Acid; Animals; Cochlear Microphonic Potentials; Ear Diseases; Endoly | 1985 |
Functional changes in a patient with aspiration pneumonitis.
Topics: Aminophylline; Barbiturates; Cephalothin; Coma; Diuretics; Female; Gentamicins; Humans; Hyperventila | 1973 |