Page last updated: 2024-10-27

gentamicin and Hypocalcemia

gentamicin has been researched along with Hypocalcemia in 13 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Hypocalcemia: Reduction of the blood calcium below normal. Manifestations include hyperactive deep tendon reflexes, Chvostek's sign, muscle and abdominal cramps, and carpopedal spasm. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
" We report the association of hypocalcemia in term and near-term neonates receiving gentamicin therapy for >/=4 days after a change in dosing from every 12 h to every 24 h."7.72Association of hypocalcemia with a change in gentamicin administration in neonates. ( Baum, M; Engle, WD; Jackson, GL; Manning, MD; Sendelbach, DM; Stehel, EK, 2003)
" A 53-year-old man admitted for recurrent infective exacerbations of chronic bronchiectasis already colonized with Pseudomonas aeruginosa was treated intermittently with intravenous gentamicin (320 to 560 mg/d) for a total of 4 months to a total cumulative dose of 9."3.73Aminoglycoside-associated Fanconi syndrome. ( Ghiculescu, RA; Kubler, PA, 2006)
"Seven patients (3 females, 4 males) developed symptomatic hypomagnesemia, hypocalcemia, and hypokalemia following gentamicin therapy."3.68Symptomatic hypomagnesemia associated with gentamicin therapy. ( Kes, P; Reiner, Z, 1990)
"A 57-year-old male developed hypomagnesemia, hypokalemia and hypocalcemia during the course of repeated gentamicin therapy."3.66Symptomatic hypomagnesemia associated with gentamicin therapy. ( Patel, R; Savage, A, 1979)
"Two patients developed severe hypomagnesemia, hypocalcemia, and hypokalemia as a result of renal wasting of magnesium and potassium shortly after being treated with large doses of gentamicin."3.65Hypomagnesemic hypocalcemia secondary to renal magnesium wasting. ( Bar, RS; Mazzaferri, EL; Wilson, HE, 1975)
"Gentamicin treatment also caused increased urinary Ca++ excretion in control rats (from 2."1.27Effect of parathyroid hormone activity on gentamicin nephrotoxicity. ( Elliott, WC; Jones, DB; Patchin, DS, 1987)
"Gentamicin was tested in vitro in blood drawn from cows, dihydrostreptomycin was tested in nonlactating cows and neomycin was tested in postpartum cows."1.26Hypocalcemic effect of aminoglycoside antibiotics in the dairy cow. ( Campbell, DL; Crawford, LM; Harvey, T, 1977)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19909 (69.23)18.7374
1990's1 (7.69)18.2507
2000's3 (23.08)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jackson, GL1
Sendelbach, DM1
Stehel, EK1
Baum, M1
Manning, MD1
Engle, WD1
Ghiculescu, RA1
Kubler, PA1
Huan, J1
Martuseviciene, G1
Olgaard, K1
Lewin, E1
Watson, A1
Coffey, L1
Keogh, B1
McCann, SR1
Drugan, A1
Itskovitz, J1
Fisher, M1
Brandes, JM1
Crawford, LM1
Campbell, DL1
Harvey, T1
Patel, R1
Savage, A1
Kelnar, CJ1
Taor, WS1
Reynolds, DJ1
Smith, DR1
Slavin, BM1
Brook, CG1
Overturf, GD1
Balfour, G1
Keating, MJ1
Sethi, MR1
Bodey, GP1
Samaan, NA1
Bar, RS1
Wilson, HE1
Mazzaferri, EL1
Kes, P1
Reiner, Z1
Elliott, WC1
Patchin, DS1
Jones, DB1

Other Studies

13 other studies available for gentamicin and Hypocalcemia

ArticleYear
Association of hypocalcemia with a change in gentamicin administration in neonates.
    Pediatric nephrology (Berlin, Germany), 2003, Volume: 18, Issue:7

    Topics: Anti-Bacterial Agents; Blood Chemical Analysis; Calcium; Dose-Response Relationship, Drug; Female; G

2003
Aminoglycoside-associated Fanconi syndrome.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 2006, Volume: 48, Issue:6

    Topics: Anti-Bacterial Agents; Bronchiectasis; Chronic Disease; Diagnosis, Differential; Fanconi Syndrome; G

2006
Calcium-sensing receptor and recovery from hypocalcaemia in thyroparathyroidectomized rats.
    European journal of clinical investigation, 2007, Volume: 37, Issue:3

    Topics: Animals; Antidotes; Egtazic Acid; Gentamicins; Hypocalcemia; Male; Parathyroidectomy; Rats; Rats, Wi

2007
Severe hypomagnesaemia and hypocalcaemia following gentamicin therapy.
    Irish medical journal, 1983, Volume: 76, Issue:9

    Topics: Adult; Female; Gentamicins; Humans; Hypocalcemia; Magnesium; Male; Middle Aged

1983
[Hypokalemia, hypocalcemia and hypomagnesemia associated with gentamicin].
    Harefuah, 1980, Volume: 99, Issue:3-4

    Topics: Adult; Female; Gentamicins; Humans; Hypocalcemia; Hypokalemia; Magnesium; Pelvic Inflammatory Diseas

1980
Hypocalcemic effect of aminoglycoside antibiotics in the dairy cow.
    Canadian journal of comparative medicine : Revue canadienne de medecine comparee, 1977, Volume: 41, Issue:3

    Topics: Aminoglycosides; Animals; Calcium; Cattle; Cattle Diseases; Dihydrostreptomycin Sulfate; Female; Gen

1977
Symptomatic hypomagnesemia associated with gentamicin therapy.
    Nephron, 1979, Volume: 23, Issue:1

    Topics: Adult; Aged; Aldosterone; Female; Gentamicins; Humans; Hypocalcemia; Hypokalemia; Magnesium Deficien

1979
Hypomagnesaemic hypocalcaemia with hypokalaemia caused by treatment with high dose gentamicin.
    Archives of disease in childhood, 1978, Volume: 53, Issue:10

    Topics: Child; Drug Administration Schedule; Gentamicins; Humans; Hypocalcemia; Hypokalemia; Magnesium Defic

1978
Osteomyelitis and sepsis: severe complications of fetal monitoring.
    Pediatrics, 1975, Volume: 55, Issue:2

    Topics: Cellulitis; Debridement; Dicloxacillin; Drainage; Electrodes, Implanted; Female; Fetus; Gentamicins;

1975
Hypocalcemia with hypoparathyroidism and renal tubular dysfunction associated with aminoglycoside therapy.
    Cancer, 1977, Volume: 39, Issue:4

    Topics: Adult; Aged; Amikacin; Aminoglycosides; Anti-Bacterial Agents; Antibiotics, Antineoplastic; Doxorubi

1977
Hypomagnesemic hypocalcemia secondary to renal magnesium wasting.
    Annals of internal medicine, 1975, Volume: 82, Issue:5

    Topics: Aged; Female; Gentamicins; Humans; Hypocalcemia; Hypokalemia; Kidney; Magnesium; Magnesium Deficienc

1975
Symptomatic hypomagnesemia associated with gentamicin therapy.
    Magnesium and trace elements, 1990, Volume: 9, Issue:1

    Topics: Aged; Female; Gentamicins; Humans; Hypocalcemia; Hypokalemia; Magnesium; Magnesium Deficiency; Male;

1990
Effect of parathyroid hormone activity on gentamicin nephrotoxicity.
    The Journal of laboratory and clinical medicine, 1987, Volume: 109, Issue:1

    Topics: Animals; Calcium; Gentamicins; Hypocalcemia; Kidney Diseases; Male; Parathyroid Glands; Parathyroid

1987