Page last updated: 2024-10-27

gentamicin and Hypertrophy

gentamicin has been researched along with Hypertrophy in 4 studies

Gentamicins: A complex of closely related aminoglycosides obtained from MICROMONOSPORA purpurea and related species. They are broad-spectrum antibiotics, but may cause ear and kidney damage. They act to inhibit PROTEIN BIOSYNTHESIS.

Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).

Research Excerpts

ExcerptRelevanceReference
"The influence of hyperfiltration-hypertrophy, proteinuria and glucosuria on the renal cortical uptake of gentamicin was studied in several experimental models."7.67Effect of hyperfiltration, proteinuria and diabetes mellitus on the uptake kinetics of gentamicin in the kidney cortex of rats. ( De Broe, ME; Giuliano, RA; Pattyn, VM; Verpooten, GA; Zheng, F, 1988)
" The early reduction in staining for epidermal growth factor and other distal tubular markers in the presence of apoptosis and hyperplasia indicates transient phenotypic simplification and implies that renal epidermal growth factor is unlikely to control PCT regeneration."3.69Hyperplasia, hypertrophy, and phenotypic alterations in the distal nephron after acute proximal tubular injury in the rat. ( Buyssens, N; De Broe, ME; Nouwen, EJ; Verstrepen, WA; Zhu, MQ, 1994)
"The influence of hyperfiltration-hypertrophy, proteinuria and glucosuria on the renal cortical uptake of gentamicin was studied in several experimental models."3.67Effect of hyperfiltration, proteinuria and diabetes mellitus on the uptake kinetics of gentamicin in the kidney cortex of rats. ( De Broe, ME; Giuliano, RA; Pattyn, VM; Verpooten, GA; Zheng, F, 1988)
"Gentamicin was still present in urine 3 mo after birth."1.28Long-term effects of mild oligonephronia induced in utero by gentamicin in the rat. ( Gilbert, T; Lelievre-Pegorier, M; Merlet-Benichou, C, 1991)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Good, PI1
Li, L1
Hurst, HA1
Serrano Herrera, I1
Xu, K1
Rao, M1
Bateman, DA1
Al-Awqati, Q1
D'Agati, VD1
Costantini, F1
Lin, F1
Nouwen, EJ1
Verstrepen, WA1
Buyssens, N1
Zhu, MQ1
De Broe, ME2
Gilbert, T1
Lelievre-Pegorier, M1
Merlet-Benichou, C1
Pattyn, VM1
Verpooten, GA1
Giuliano, RA1
Zheng, F1

Other Studies

4 other studies available for gentamicin and Hypertrophy

ArticleYear
Low nephron endowment increases susceptibility to renal stress and chronic kidney disease.
    JCI insight, 2023, 02-08, Volume: 8, Issue:3

    Topics: Acute Kidney Injury; Animals; Female; Gentamicins; Humans; Hypertrophy; Infant, Premature; Kidney; M

2023
Hyperplasia, hypertrophy, and phenotypic alterations in the distal nephron after acute proximal tubular injury in the rat.
    Laboratory investigation; a journal of technical methods and pathology, 1994, Volume: 70, Issue:4

    Topics: Animals; Apoptosis; Cell Division; Epidermal Growth Factor; Female; Gentamicins; Hyperplasia; Hypert

1994
Long-term effects of mild oligonephronia induced in utero by gentamicin in the rat.
    Pediatric research, 1991, Volume: 30, Issue:5

    Topics: Abnormalities, Drug-Induced; Age Factors; Animals; Female; Gentamicins; Glomerular Filtration Rate;

1991
Effect of hyperfiltration, proteinuria and diabetes mellitus on the uptake kinetics of gentamicin in the kidney cortex of rats.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:2

    Topics: Animals; Diabetes Mellitus, Experimental; Female; Gentamicins; Glomerular Filtration Rate; Hypertrop

1988